TreeWAS – Variant ID: rs13178541

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
M81.99 Osteoporosis, unspecified (Site unspecified)	0.178	0.822
M81.9 Osteoporosis, unspecified	0.172	0.828
M81.98 Osteoporosis, unspecified (Other)	0.142	0.858
M81 Osteoporosis without pathological fracture	0.141	0.859
M81.90 Osteoporosis, unspecified (Multiple sites)	0.138	0.862
M81.91 Osteoporosis, unspecified (Shoulder region)	0.137	0.862
M81.93 Osteoporosis, unspecified (Forearm)	0.137	0.863
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.131	0.869
M81.92 Osteoporosis, unspecified (Upper arm)	0.130	0.870
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.130	0.870
M81.94 Osteoporosis, unspecified (Hand)	0.128	0.871
M81.96 Osteoporosis, unspecified (Lower leg)	0.120	0.880
M81.8 Other osteoporosis	0.116	0.884
M80-M85 Disorders of bone density and structure	0.114	0.886
M81.3 Postsurgical malabsorption osteoporosis	0.108	0.892
M81.2 Osteoporosis of disuse	0.105	0.895
M84 Disorders of continuity of bone	0.104	0.896
M81.1 Postoophorectomy osteoporosis	0.103	0.897
M81.6 Localised osteoporosis [Lequesne]	0.102	0.898
M81.5 Idiopathic osteoporosis	0.102	0.898
M81.0 Postmenopausal osteoporosis	0.099	0.900
M84.0 Malunion of fracture	0.094	0.906
M81.80 Other osteoporosis (Multiple sites)	0.092	0.908
M84.4 Pathological fracture, not elsewhere classified	0.091	0.909
M81.89 Other osteoporosis (Site unspecified)	0.090	0.910
M82 Osteoporosis in diseases classified elsewhere	0.084	0.916
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.083	0.916
M83 Adult osteomalacia	0.083	0.917
M81.88 Other osteoporosis (Other)	0.083	0.917
M81.87 Other osteoporosis (Ankle and foot)	0.083	0.917
M81.86 Other osteoporosis (Lower leg)	0.083	0.917
M81.85 Other osteoporosis (Pelvic region and thigh)	0.083	0.917
M81.84 Other osteoporosis (Hand)	0.083	0.917
M81.83 Other osteoporosis (Forearm)	0.083	0.917
M81.82 Other osteoporosis (Upper arm)	0.083	0.917
M81.81 Other osteoporosis (Shoulder region)	0.083	0.917
M85 Other disorders of bone density and structure	0.080	0.920
M84.2 Delayed union of fracture	0.080	0.920
M81.4 Drug-induced osteoporosis	0.078	0.921
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.078	0.922
M81.20 Osteoporosis of disuse (Multiple sites)	0.078	0.922
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.077	0.923
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.077	0.923
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.077	0.923
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.077	0.923
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.077	0.923
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.077	0.923
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.077	0.923
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.077	0.923
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.077	0.923
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.076	0.924
M84.8 Other disorders of continuity of bone	0.075	0.924
M81.29 Osteoporosis of disuse (Site unspecified)	0.075	0.925
M81.28 Osteoporosis of disuse (Other)	0.075	0.925
M81.27 Osteoporosis of disuse (Ankle and foot)	0.075	0.925
M81.26 Osteoporosis of disuse (Lower leg)	0.075	0.925
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.075	0.925
M81.24 Osteoporosis of disuse (Hand)	0.075	0.925
M81.23 Osteoporosis of disuse (Forearm)	0.075	0.925
M81.22 Osteoporosis of disuse (Upper arm)	0.075	0.925
M81.21 Osteoporosis of disuse (Shoulder region)	0.075	0.925
M84.02 Malunion of fracture (Upper arm)	0.075	0.925
M84.48 Pathological fracture, not elsewhere classified (Other)	0.075	0.925
M84.3 Stress fracture, not elsewhere classified	0.075	0.925
M84.9 Disorder of continuity of bone, unspecified	0.075	0.925
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.074	0.926
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.074	0.926
M81.18 Postoophorectomy osteoporosis (Other)	0.074	0.926
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.074	0.926
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.074	0.926
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.074	0.926
M81.14 Postoophorectomy osteoporosis (Hand)	0.074	0.926
M81.13 Postoophorectomy osteoporosis (Forearm)	0.074	0.926
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.074	0.926
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.074	0.926
M62 Other disorders of muscle	0.073	0.927
M84.04 Malunion of fracture (Hand)	0.073	0.927
M81.59 Idiopathic osteoporosis (Site unspecified)	0.073	0.927
M81.58 Idiopathic osteoporosis (Other)	0.073	0.927
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.073	0.927
M81.56 Idiopathic osteoporosis (Lower leg)	0.073	0.927
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.073	0.927
M81.54 Idiopathic osteoporosis (Hand)	0.073	0.927
M81.53 Idiopathic osteoporosis (Forearm)	0.073	0.927
M81.52 Idiopathic osteoporosis (Upper arm)	0.073	0.927
M81.51 Idiopathic osteoporosis (Shoulder region)	0.073	0.927
M81.50 Idiopathic osteoporosis (Multiple sites)	0.073	0.927
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.073	0.927
M81.68 Localized osteoporosis [Lequesne] (Other)	0.073	0.927
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.073	0.927
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.073	0.927
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.073	0.927
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.073	0.927
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.073	0.927
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.073	0.927
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.073	0.927
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.073	0.927
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.073	0.927
M60-M63 Disorders of muscles	0.072	0.928
M84.07 Malunion of fracture (Ankle and foot)	0.072	0.928
M84.05 Malunion of fracture (Pelvic region and thigh)	0.072	0.928
M84.03 Malunion of fracture (Forearm)	0.072	0.928
M81.08 Postmenopausal osteoporosis (Other)	0.071	0.928
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.071	0.928
M81.06 Postmenopausal osteoporosis (Lower leg)	0.071	0.928
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.071	0.928
M81.04 Postmenopausal osteoporosis (Hand)	0.071	0.928
M81.03 Postmenopausal osteoporosis (Forearm)	0.071	0.928
M81.02 Postmenopausal osteoporosis (Upper arm)	0.071	0.928
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.071	0.928
M62.8 Other specified disorders of muscle	0.072	0.928
M84.08 Malunion of fracture (Other)	0.071	0.929
M84.06 Malunion of fracture (Lower leg)	0.071	0.929
M05-M14 Inflammatory polyarthropathies	0.070	0.930
M84.01 Malunion of fracture (Shoulder region)	0.068	0.932
M84.09 Malunion of fracture (Site unspecified)	0.068	0.932
M84.00 Malunion of fracture (Multiple sites)	0.068	0.932
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.067	0.933
M06 Other rheumatoid arthritis	0.067	0.933
M45-M49 Spondylopathies	0.067	0.933
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.067	0.933
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.066	0.933
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.066	0.934
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.066	0.934
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.066	0.934
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.066	0.934
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.066	0.934
M80 Osteoporosis with pathological fracture	0.065	0.935
M00-M03 Infectious arthropathies	0.064	0.936
M45 Ankylosing spondylitis	0.064	0.936
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.064	0.936
M83.9 Adult osteomalacia, unspecified	0.064	0.936
M07 Psoriatic and enteropathic arthropathies	0.064	0.936
M06.9 Rheumatoid arthritis, unspecified	0.063	0.937
M82.1 Osteoporosis in endocrine disorders	0.063	0.937
M06.3 Rheumatoid nodule	0.063	0.937
M84.26 Delayed union of fracture (Lower leg)	0.062	0.938
M45.X9 Ankylosing spondylitis (Site unspecified)	0.062	0.938
M62.80 Other specified disorders of muscle (Multiple sites)	0.062	0.938
M62.89 Other specified disorders of muscle (Site unspecified)	0.062	0.938
M83.1 Senile osteomalacia	0.061	0.939
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.061	0.939
M85.8 Other specified disorders of bone density and structure	0.061	0.939
M82.8 Osteoporosis in other diseases classified elsewhere	0.060	0.939
M82.0 Osteoporosis in multiple myelomatosis	0.060	0.939
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.060	0.939
M84.21 Delayed union of fracture (Shoulder region)	0.060	0.939
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.060	0.940
M83.5 Other drug-induced osteomalacia in adults	0.060	0.940
M83.4 Aluminum bone disease	0.060	0.940
M83.2 Adult osteomalacia due to malabsorption	0.060	0.940
M83.0 Puerperal osteomalacia	0.060	0.940
M62.88 Other specified disorders of muscle (Other)	0.059	0.940
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.059	0.940
M85.6 Other cyst of bone	0.059	0.941
M00 Pyogenic arthritis	0.059	0.941
M05 Seropositive rheumatoid arthritis	0.059	0.941
M62.0 Diastasis of muscle	0.058	0.942
M07.3 Other psoriatic arthropathies	0.058	0.942
M83.3 Adult osteomalacia due to malnutrition	0.058	0.942
M83.8 Other adult osteomalacia	0.057	0.942
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.057	0.942
M85.4 Solitary bone cyst	0.057	0.942
M62.82 Other specified disorders of muscle (Upper arm)	0.057	0.942
M85.5 Aneurysmal bone cyst	0.057	0.943
M85.3 Osteitis condensans	0.057	0.943
M85.1 Skeletal fluorosis	0.057	0.943
M91-M94 Chondropathies	0.057	0.943
M84.29 Delayed union of fracture (Site unspecified)	0.057	0.943
M84.28 Delayed union of fracture (Other)	0.057	0.943
M84.24 Delayed union of fracture (Hand)	0.057	0.943
M84.23 Delayed union of fracture (Forearm)	0.057	0.943
M84.20 Delayed union of fracture (Multiple sites)	0.057	0.943
M85.0 Fibrous dysplasia (monostotic)	0.057	0.943
M81.48 Drug-induced osteoporosis (Other)	0.056	0.943
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.056	0.943
M81.46 Drug-induced osteoporosis (Lower leg)	0.056	0.943
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.056	0.943
M81.44 Drug-induced osteoporosis (Hand)	0.056	0.943
M81.43 Drug-induced osteoporosis (Forearm)	0.056	0.943
M81.42 Drug-induced osteoporosis (Upper arm)	0.056	0.943
M81.41 Drug-induced osteoporosis (Shoulder region)	0.056	0.943
M06.4 Inflammatory polyarthropathy	0.057	0.943
M62.9 Disorder of muscle, unspecified	0.056	0.944
M84.83 Other disorders of continuity of bone (Forearm)	0.055	0.944
M84.22 Delayed union of fracture (Upper arm)	0.055	0.945
M84.27 Delayed union of fracture (Ankle and foot)	0.055	0.945
M85.2 Hyperostosis of skull	0.055	0.945
M62.6 Muscle strain	0.055	0.945
M06.34 Rheumatoid nodule (Hand)	0.055	0.945
M84.89 Other disorders of continuity of bone (Site unspecified)	0.054	0.946
M84.88 Other disorders of continuity of bone (Other)	0.054	0.946
M84.86 Other disorders of continuity of bone (Lower leg)	0.054	0.946
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.054	0.946
M84.84 Other disorders of continuity of bone (Hand)	0.054	0.946
M84.82 Other disorders of continuity of bone (Upper arm)	0.054	0.946
M84.81 Other disorders of continuity of bone (Shoulder region)	0.054	0.946
M84.80 Other disorders of continuity of bone (Multiple sites)	0.054	0.946
M10 Gout	0.054	0.946
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.054	0.946
M00.9 Pyogenic arthritis, unspecified	0.054	0.946
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.054	0.946
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.054	0.946
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.054	0.946
M84.38 Stress fracture, not elsewhere classified (Other)	0.054	0.946
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.054	0.946
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.054	0.946
M84.34 Stress fracture, not elsewhere classified (Hand)	0.054	0.946
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.054	0.946
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.054	0.946
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.054	0.946
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.054	0.946
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.054	0.946
M84.98 Disorder of continuity of bone, unspecified (Other)	0.054	0.946
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.054	0.946
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.054	0.946
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.054	0.946
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.054	0.946
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.054	0.946
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.054	0.946
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.054	0.946
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.054	0.946
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.053	0.947
M62.83 Other specified disorders of muscle (Forearm)	0.053	0.947
M07.39 Other psoriatic arthropathies (Site unspecified)	0.053	0.947
M62.81 Other specified disorders of muscle (Shoulder region)	0.053	0.947
M62.86 Other specified disorders of muscle (Lower leg)	0.053	0.947
M62.2 Ischaemic infarction of muscle	0.053	0.947
M45.X2 Ankylosing spondylitis (Cervical region)	0.053	0.947
M62.3 Immobility syndrome (paraplegic)	0.053	0.947
M47 Spondylosis	0.053	0.947
M63 Disorders of muscle in diseases classified elsewhere	0.052	0.948
M61 Calcification and ossification of muscle	0.052	0.948
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.052	0.948
M62.4 Contracture of muscle	0.052	0.948
M85.9 Disorder of bone density and structure, unspecified	0.052	0.948
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.052	0.948
M06.30 Rheumatoid nodule (Multiple sites)	0.052	0.948
M65-M68 Disorders of synovium and tendon	0.052	0.948
M06.37 Rheumatoid nodule (Ankle and foot)	0.051	0.948
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.051	0.948
M60 Myositis	0.051	0.949
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.051	0.949
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.051	0.949
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.051	0.949
M93 Other osteochondropathies	0.051	0.949
M47.1 Other spondylosis with myelopathy	0.051	0.949
M09 Juvenile arthritis in diseases classified elsewhere	0.050	0.949
M62.87 Other specified disorders of muscle (Ankle and foot)	0.050	0.950
M06.1 Adult-onset Still's disease	0.050	0.950
M48 Other spondylopathies	0.050	0.950
M07.30 Other psoriatic arthropathies (Multiple sites)	0.050	0.950
M08 Juvenile arthritis	0.050	0.950
M80.5 Idiopathic osteoporosis with pathological fracture	0.050	0.950
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.050	0.950
M83.99 Adult osteomalacia, unspecified (Site unspecified)	0.050	0.950
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.050	0.950
M81.49 Drug-induced osteoporosis (Site unspecified)	0.049	0.950
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.049	0.951
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.049	0.951
M05.9 Seropositive rheumatoid arthritis, unspecified	0.049	0.951
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.049	0.951
M06.2 Rheumatoid bursitis	0.048	0.951
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.048	0.952
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.048	0.952
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.048	0.952
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.048	0.952
M45.X6 Ankylosing spondylitis (Lumbar region)	0.048	0.952
M12 Other specific arthropathies	0.048	0.952
M07.6 Other enteropathic arthropathies	0.048	0.952
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.048	0.952
M62.84 Other specified disorders of muscle (Hand)	0.048	0.952
M49 Spondylopathies in diseases classified elsewhere	0.048	0.952
M62.08 Diastasis of muscle (Other)	0.048	0.952
M47.12 Other spondylosis with myelopathy (Cervical region)	0.048	0.952
M62.1 Other rupture of muscle (nontraumatic)	0.047	0.952
M85.83 Other specified disorders of bone density and structure (Forearm)	0.047	0.953
M80.4 Drug-induced osteoporosis with pathological fracture	0.047	0.953
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.047	0.953
M80.2 Osteoporosis of disuse with pathological fracture	0.047	0.953
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.047	0.953
M10.9 Gout, unspecified	0.047	0.953
M93.9 Osteochondropathy, unspecified	0.047	0.953
M07.38 Other psoriatic arthropathies (Other)	0.047	0.953
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.046	0.953
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.046	0.953
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.046	0.953
M67 Other disorders of synovium and tendon	0.046	0.954
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.046	0.954
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.046	0.954
M45.X4 Ankylosing spondylitis (Thoracic region)	0.046	0.954
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.046	0.954
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.046	0.954
M02 Reactive arthropathies	0.046	0.954
M85.68 Other cyst of bone (Other)	0.046	0.954
M99 Biomechanical lesions, not elsewhere classified	0.046	0.954
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.046	0.954
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.046	0.954
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.046	0.954
M06.36 Rheumatoid nodule (Lower leg)	0.046	0.954
M83.98 Adult osteomalacia, unspecified (Other)	0.046	0.954
M83.97 Adult osteomalacia, unspecified (Ankle and foot)	0.046	0.954
M83.96 Adult osteomalacia, unspecified (Lower leg)	0.046	0.954
M83.95 Adult osteomalacia, unspecified (Pelvic region and thigh)	0.046	0.954
M83.94 Adult osteomalacia, unspecified (Hand)	0.046	0.954
M83.93 Adult osteomalacia, unspecified (Forearm)	0.046	0.954
M83.92 Adult osteomalacia, unspecified (Upper arm)	0.046	0.954
M83.91 Adult osteomalacia, unspecified (Shoulder region)	0.046	0.954
M83.90 Adult osteomalacia, unspecified (Multiple sites)	0.046	0.954
M07.5 Arthropathy in ulcerative colitis	0.046	0.954
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.046	0.954
M07.2 Psoriatic spondylitis	0.046	0.954
M07.1 Arthritis mutilans	0.046	0.954
M07.0 Distal interphalangeal psoriatic arthropathy	0.046	0.954
M85.66 Other cyst of bone (Lower leg)	0.046	0.954
M85.64 Other cyst of bone (Hand)	0.046	0.954
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.045	0.955
M11 Other crystal arthropathies	0.045	0.955
M83.12 Senile osteomalacia (Upper arm)	0.045	0.955
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.045	0.955
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.045	0.955
M82.18 Osteoporosis in endocrine disorders (Other)	0.045	0.955
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.045	0.955
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.045	0.955
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.045	0.955
M82.14 Osteoporosis in endocrine disorders (Hand)	0.045	0.955
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.045	0.955
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.045	0.955
M06.39 Rheumatoid nodule (Site unspecified)	0.045	0.955
M06.38 Rheumatoid nodule (Other)	0.045	0.955
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.045	0.955
M06.31 Rheumatoid nodule (Shoulder region)	0.045	0.955
M00.0 Staphylococcal arthritis and polyarthritis	0.045	0.955
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.045	0.955
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.045	0.955
M14 Arthropathies in other diseases classified elsewhere	0.045	0.955
M62.66 Muscle strain (Lower leg)	0.045	0.955
M06.32 Rheumatoid nodule (Upper arm)	0.044	0.955
M05.2 Rheumatoid vasculitis	0.044	0.955
M81.40 Drug-induced osteoporosis (Multiple sites)	0.044	0.956
M83.19 Senile osteomalacia (Site unspecified)	0.044	0.956
M83.18 Senile osteomalacia (Other)	0.044	0.956
M83.17 Senile osteomalacia (Ankle and foot)	0.044	0.956
M83.16 Senile osteomalacia (Lower leg)	0.044	0.956
M83.15 Senile osteomalacia (Pelvic region and thigh)	0.044	0.956
M83.14 Senile osteomalacia (Hand)	0.044	0.956
M83.13 Senile osteomalacia (Forearm)	0.044	0.956
M83.11 Senile osteomalacia (Shoulder region)	0.044	0.956
M83.10 Senile osteomalacia (Multiple sites)	0.044	0.956
M85.84 Other specified disorders of bone density and structure (Hand)	0.044	0.956
M05.1 Rheumatoid lung disease	0.044	0.956
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.043	0.956
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.043	0.956
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.043	0.956
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.043	0.956
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.043	0.956
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.043	0.956
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.043	0.956
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.043	0.956
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)	0.043	0.956
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)	0.043	0.956
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)	0.043	0.956
M82.88 Osteoporosis in other diseases classified elsewhere (Other)	0.043	0.956
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)	0.043	0.956
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)	0.043	0.956
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)	0.043	0.956
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)	0.043	0.956
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)	0.043	0.956
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)	0.043	0.956
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)	0.043	0.956
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)	0.043	0.956
M62.96 Disorder of muscle, unspecified (Lower leg)	0.043	0.957
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.043	0.957
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.043	0.957
M83.09 Puerperal osteomalacia (Site unspecified)	0.043	0.957
M83.08 Puerperal osteomalacia (Other)	0.043	0.957
M83.07 Puerperal osteomalacia (Ankle and foot)	0.043	0.957
M83.06 Puerperal osteomalacia (Lower leg)	0.043	0.957
M83.05 Puerperal osteomalacia (Pelvic region and thigh)	0.043	0.957
M83.04 Puerperal osteomalacia (Hand)	0.043	0.957
M83.03 Puerperal osteomalacia (Forearm)	0.043	0.957
M83.02 Puerperal osteomalacia (Upper arm)	0.043	0.957
M83.01 Puerperal osteomalacia (Shoulder region)	0.043	0.957
M83.00 Puerperal osteomalacia (Multiple sites)	0.043	0.957
M83.29 Adult osteomalacia due to malabsorption (Site unspecified)	0.043	0.957
M83.28 Adult osteomalacia due to malabsorption (Other)	0.043	0.957
M83.27 Adult osteomalacia due to malabsorption (Ankle and foot)	0.043	0.957
M83.26 Adult osteomalacia due to malabsorption (Lower leg)	0.043	0.957
M83.25 Adult osteomalacia due to malabsorption (Pelvic region and thigh)	0.043	0.957
M83.24 Adult osteomalacia due to malabsorption (Hand)	0.043	0.957
M83.23 Adult osteomalacia due to malabsorption (Forearm)	0.043	0.957
M83.22 Adult osteomalacia due to malabsorption (Upper arm)	0.043	0.957
M83.21 Adult osteomalacia due to malabsorption (Shoulder region)	0.043	0.957
M83.20 Adult osteomalacia due to malabsorption (Multiple sites)	0.043	0.957
M83.49 Aluminium bone disease (Site unspecified)	0.043	0.957
M83.48 Aluminium bone disease (Other)	0.043	0.957
M83.47 Aluminium bone disease (Ankle and foot)	0.043	0.957
M83.46 Aluminium bone disease (Lower leg)	0.043	0.957
M83.45 Aluminium bone disease (Pelvic region and thigh)	0.043	0.957
M83.44 Aluminium bone disease (Hand)	0.043	0.957
M83.43 Aluminium bone disease (Forearm)	0.043	0.957
M83.42 Aluminium bone disease (Upper arm)	0.043	0.957
M83.41 Aluminium bone disease (Shoulder region)	0.043	0.957
M83.40 Aluminium bone disease (Multiple sites)	0.043	0.957
M83.59 Other drug-induced osteomalacia in adults (Site unspecified)	0.043	0.957
M83.58 Other drug-induced osteomalacia in adults (Other)	0.043	0.957
M83.57 Other drug-induced osteomalacia in adults (Ankle and foot)	0.043	0.957
M83.56 Other drug-induced osteomalacia in adults (Lower leg)	0.043	0.957
M83.55 Other drug-induced osteomalacia in adults (Pelvic region and thigh)	0.043	0.957
M83.54 Other drug-induced osteomalacia in adults (Hand)	0.043	0.957
M83.53 Other drug-induced osteomalacia in adults (Forearm)	0.043	0.957
M83.52 Other drug-induced osteomalacia in adults (Upper arm)	0.043	0.957
M83.51 Other drug-induced osteomalacia in adults (Shoulder region)	0.043	0.957
M83.50 Other drug-induced osteomalacia in adults (Multiple sites)	0.043	0.957
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.043	0.957
M85.47 Solitary bone cyst (Ankle and foot)	0.043	0.957
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.043	0.957
M96.0 Pseudarthrosis after fusion or arthrodesis	0.043	0.957
M48.5 Collapsed vertebra, not elsewhere classified	0.043	0.957
M06.46 Inflammatory polyarthropathy (Lower leg)	0.043	0.957
M67.8 Other specified disorders of synovium and tendon	0.043	0.957
M85.69 Other cyst of bone (Site unspecified)	0.042	0.957
M85.63 Other cyst of bone (Forearm)	0.042	0.957
M85.62 Other cyst of bone (Upper arm)	0.042	0.957
M85.61 Other cyst of bone (Shoulder region)	0.042	0.957
M85.60 Other cyst of bone (Multiple sites)	0.042	0.957
M80.0 Postmenopausal osteoporosis with pathological fracture	0.042	0.957
M05.0 Felty's syndrome	0.042	0.957
M06.33 Rheumatoid nodule (Forearm)	0.042	0.958
M92 Other juvenile osteochondrosis	0.042	0.958
M00.2 Other streptococcal arthritis and polyarthritis	0.042	0.958
M00.1 Pneumococcal arthritis and polyarthritis	0.042	0.958
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.042	0.958
M62.09 Diastasis of muscle (Site unspecified)	0.042	0.958
M62.07 Diastasis of muscle (Ankle and foot)	0.042	0.958
M62.06 Diastasis of muscle (Lower leg)	0.042	0.958
M62.05 Diastasis of muscle (Pelvic region and thigh)	0.042	0.958
M62.04 Diastasis of muscle (Hand)	0.042	0.958
M62.03 Diastasis of muscle (Forearm)	0.042	0.958
M62.02 Diastasis of muscle (Upper arm)	0.042	0.958
M62.01 Diastasis of muscle (Shoulder region)	0.042	0.958
M62.00 Diastasis of muscle (Multiple sites)	0.042	0.958
M07.33 Other psoriatic arthropathies (Forearm)	0.042	0.958
M07.32 Other psoriatic arthropathies (Upper arm)	0.042	0.958
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.042	0.958
M83.39 Adult osteomalacia due to malnutrition (Site unspecified)	0.042	0.958
M83.38 Adult osteomalacia due to malnutrition (Other)	0.042	0.958
M83.37 Adult osteomalacia due to malnutrition (Ankle and foot)	0.042	0.958
M83.36 Adult osteomalacia due to malnutrition (Lower leg)	0.042	0.958
M83.35 Adult osteomalacia due to malnutrition (Pelvic region and thigh)	0.042	0.958
M83.34 Adult osteomalacia due to malnutrition (Hand)	0.042	0.958
M83.33 Adult osteomalacia due to malnutrition (Forearm)	0.042	0.958
M83.32 Adult osteomalacia due to malnutrition (Upper arm)	0.042	0.958
M83.31 Adult osteomalacia due to malnutrition (Shoulder region)	0.042	0.958
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.042	0.958
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.042	0.958
M91 Juvenile osteochondrosis of hip and pelvis	0.042	0.958
M40-M43 Deforming dorsopathies	0.042	0.958
M83.89 Other adult osteomalacia (Site unspecified)	0.041	0.958
M83.88 Other adult osteomalacia (Other)	0.041	0.958
M83.87 Other adult osteomalacia (Ankle and foot)	0.041	0.958
M83.86 Other adult osteomalacia (Lower leg)	0.041	0.958
M83.85 Other adult osteomalacia (Pelvic region and thigh)	0.041	0.958
M83.84 Other adult osteomalacia (Hand)	0.041	0.958
M83.83 Other adult osteomalacia (Forearm)	0.041	0.958
M83.82 Other adult osteomalacia (Upper arm)	0.041	0.958
M83.81 Other adult osteomalacia (Shoulder region)	0.041	0.958
M85.49 Solitary bone cyst (Site unspecified)	0.041	0.958
M85.48 Solitary bone cyst (Other)	0.041	0.958
M85.44 Solitary bone cyst (Hand)	0.041	0.958
M85.43 Solitary bone cyst (Forearm)	0.041	0.958
M85.42 Solitary bone cyst (Upper arm)	0.041	0.958
M85.41 Solitary bone cyst (Shoulder region)	0.041	0.958
M85.40 Solitary bone cyst (Multiple sites)	0.041	0.958
M06.98 Rheumatoid arthritis, unspecified (Other)	0.041	0.958
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.041	0.958
M85.19 Skeletal fluorosis (Site unspecified)	0.041	0.959
M85.18 Skeletal fluorosis (Other)	0.041	0.959
M85.17 Skeletal fluorosis (Ankle and foot)	0.041	0.959
M85.16 Skeletal fluorosis (Lower leg)	0.041	0.959
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.041	0.959
M85.14 Skeletal fluorosis (Hand)	0.041	0.959
M85.13 Skeletal fluorosis (Forearm)	0.041	0.959
M85.12 Skeletal fluorosis (Upper arm)	0.041	0.959
M85.11 Skeletal fluorosis (Shoulder region)	0.041	0.959
M85.10 Skeletal fluorosis (Multiple sites)	0.041	0.959
M85.39 Osteitis condensans (Site unspecified)	0.041	0.959
M85.38 Osteitis condensans (Other)	0.041	0.959
M85.37 Osteitis condensans (Ankle and foot)	0.041	0.959
M85.36 Osteitis condensans (Lower leg)	0.041	0.959
M85.35 Osteitis condensans (Pelvic region and thigh)	0.041	0.959
M85.34 Osteitis condensans (Hand)	0.041	0.959
M85.33 Osteitis condensans (Forearm)	0.041	0.959
M85.32 Osteitis condensans (Upper arm)	0.041	0.959
M85.31 Osteitis condensans (Shoulder region)	0.041	0.959
M85.30 Osteitis condensans (Multiple sites)	0.041	0.959
M85.59 Aneurysmal bone cyst (Site unspecified)	0.041	0.959
M85.58 Aneurysmal bone cyst (Other)	0.041	0.959
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.041	0.959
M85.56 Aneurysmal bone cyst (Lower leg)	0.041	0.959

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations