TreeWAS – Variant ID: rs13218732

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.012	0.988	0.000
E21.0 Primary hyperparathyroidism	0.011	0.989	0.000
E21.3 Hyperparathyroidism, unspecified	0.011	0.989	0.000
E20-E35 Disorders of other endocrine glands	0.010	0.989	0.000
R94.5 Abnormal results of liver function studies	0.010	0.990	0.000
E27 Other disorders of adrenal gland	0.010	0.990	0.000
E23 Hypofunction and other disorders of pituitary gland	0.010	0.990	0.000
E23.0 Hypopituitarism	0.009	0.991	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.008	0.991	0.000
E21.4 Other specified disorders of parathyroid gland	0.008	0.991	0.000
E21.2 Other hyperparathyroidism	0.008	0.991	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.008	0.991	0.000
E20 Hypoparathyroidism	0.008	0.991	0.000
E27.1 Primary adrenocortical insufficiency	0.008	0.992	0.000
E27.2 Addisonian crisis	0.008	0.992	0.000
E24 Cushing's syndrome	0.008	0.992	0.000
E26 Hyperaldosteronism	0.008	0.992	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.008	0.992	0.000
E34 Other endocrine disorders	0.008	0.992	0.000
E32 Diseases of thymus	0.008	0.992	0.000
E31 Polyglandular dysfunction	0.008	0.992	0.000
E30 Disorders of puberty, not elsewhere classified	0.008	0.992	0.000
E25 Adrenogenital disorders	0.008	0.992	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.008	0.992	0.000
E28 Ovarian dysfunction	0.007	0.992	0.000
E22 Hyperfunction of pituitary gland	0.007	0.993	0.000
E27.9 Disorder of adrenal gland, unspecified	0.007	0.993	0.000
E27.8 Other specified disorders of adrenal gland	0.007	0.993	0.000
E27.5 Adrenomedullary hyperfunction	0.007	0.993	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.007	0.993	0.000
E27.0 Other adrenocortical overactivity	0.007	0.993	0.000
E23.2 Diabetes insipidus	0.007	0.993	0.000
E23.7 Disorder of pituitary gland, unspecified	0.007	0.993	0.000
E23.6 Other disorders of pituitary gland	0.007	0.993	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.007	0.993	0.000
E23.1 Drug-induced hypopituitarism	0.007	0.993	0.000
E29 Testicular dysfunction	0.007	0.993	0.000
E20.9 Hypoparathyroidism, unspecified	0.007	0.993	0.000
E24.9 Cushing's syndrome, unspecified	0.006	0.993	0.000
E20.8 Other hypoparathyroidism	0.006	0.994	0.000
E20.1 Pseudohypoparathyroidism	0.006	0.994	0.000
E20.0 Idiopathic hypoparathyroidism	0.006	0.994	0.000
E26.0 Primary hyperaldosteronism	0.006	0.994	0.000
E24.8 Other Cushing's syndrome	0.006	0.994	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.006	0.994	0.000
E24.3 Ectopic ACTH syndrome	0.006	0.994	0.000
E24.2 Drug-induced Cushing's syndrome	0.006	0.994	0.000
E24.1 Nelson's syndrome	0.006	0.994	0.000
E24.0 Pituitary-dependent Cushing's disease	0.006	0.994	0.000
E26.9 Hyperaldosteronism, unspecified	0.006	0.994	0.000
E26.8 Other hyperaldosteronism	0.006	0.994	0.000
E26.1 Secondary hyperaldosteronism	0.006	0.994	0.000
E25.9 Adrenogenital disorder, unspecified	0.006	0.994	0.000
E25.8 Other adrenogenital disorders	0.006	0.994	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.006	0.994	0.000
E30.9 Disorder of puberty, unspecified	0.006	0.994	0.000
E30.8 Other disorders of puberty	0.006	0.994	0.000
E30.1 Precocious puberty	0.006	0.994	0.000
E30.0 Delayed puberty	0.006	0.994	0.000
E31.9 Polyglandular dysfunction, unspecified	0.006	0.994	0.000
E31.8 Other polyglandular dysfunction	0.006	0.994	0.000
E31.1 Polyglandular hyperfunction	0.006	0.994	0.000
E31.0 Autoimmune polyglandular failure	0.006	0.994	0.000
E32.9 Disease of thymus, unspecified	0.006	0.994	0.000
E32.8 Other diseases of thymus	0.006	0.994	0.000
E32.1 Abscess of thymus	0.006	0.994	0.000
E32.0 Persistent hyperplasia of thymus	0.006	0.994	0.000
E34.9 Endocrine disorder, unspecified	0.006	0.994	0.000
E34.8 Other specified endocrine disorders	0.006	0.994	0.000
E34.5 Androgen resistance syndrome	0.006	0.994	0.000
E34.4 Constitutional tall stature	0.006	0.994	0.000
E34.3 Short stature, not elsewhere classified	0.006	0.994	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.006	0.994	0.000
E34.1 Other hypersecretion of intestinal hormones	0.006	0.994	0.000
E34.0 Carcinoid syndrome	0.006	0.994	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.006	0.994	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.006	0.994	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.006	0.994	0.000
E28.9 Ovarian dysfunction, unspecified	0.006	0.994	0.000
E28.8 Other ovarian dysfunction	0.006	0.994	0.000
E28.3 Primary ovarian failure	0.006	0.994	0.000
E28.1 Androgen excess	0.006	0.994	0.000
E28.0 Oestrogen excess	0.006	0.994	0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.000	0.994	0.006
E22.0 Acromegaly and pituitary gigantism	0.005	0.994	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.005	0.994	0.000
E22.8 Other hyperfunction of pituitary gland	0.005	0.994	0.000
E22.1 Hyperprolactinaemia	0.005	0.994	0.000
E28.2 Polycystic ovarian syndrome	0.005	0.994	0.000
E29.9 Testicular dysfunction, unspecified	0.005	0.995	0.000
E29.8 Other testicular dysfunction	0.005	0.995	0.000
E29.0 Testicular hyperfunction	0.005	0.995	0.000
E16.2 Hypoglycaemia, unspecified	0.005	0.995	0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.000	0.995	0.005
E16 Other disorders of pancreatic internal secretion	0.005	0.995	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.005	0.995	0.000
E83.5 Disorders of calcium metabolism	0.005	0.995	0.000
E29.1 Testicular hypofunction	0.004	0.995	0.000
N39.4 Other specified urinary incontinence	0.000	0.995	0.005
E16.0 Drug-induced hypoglycaemia without coma	0.004	0.996	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.004	0.996	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.000	0.996	0.004
T78.4 Allergy, unspecified	0.004	0.996	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.004	0.996	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.004	0.996	0.000
E16.4 Abnormal secretion of gastrin	0.004	0.996	0.000
E16.3 Increased secretion of glucagon	0.004	0.996	0.000
E16.1 Other hypoglycaemia	0.004	0.996	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.004	0.996	0.000
Z50.2 Alcohol rehabilitation	0.000	0.996	0.004
Z50 Care involving use of rehabilitation procedures	0.000	0.996	0.004
T78.2 Anaphylactic shock, unspecified	0.004	0.996	0.000
T78 Adverse effects, not elsewhere classified	0.004	0.996	0.000
E83 Disorders of mineral metabolism	0.004	0.996	0.000
T78.3 Angioneurotic oedema	0.003	0.997	0.000
E15 Nondiabetic hypoglycaemic coma	0.003	0.997	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.003	0.997	0.000
K35.9 Acute appendicitis, unspecified	0.003	0.997	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.000	0.997	0.003
R94 Abnormal results of function studies	0.003	0.997	0.000
E40-E46 Malnutrition	0.003	0.997	0.000
E83.4 Disorders of magnesium metabolism	0.003	0.997	0.000
Z50.6 Orthoptic training	0.000	0.997	0.003
Z50.4 Psychotherapy, not elsewhere classified	0.000	0.997	0.003
Z50.3 Drug rehabilitation	0.000	0.997	0.003
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.003	0.997	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.003	0.997	0.000
E00-E07 Disorders of thyroid gland	0.003	0.997	0.000
T78.9 Adverse effect, unspecified	0.003	0.997	0.000
T78.8 Other adverse effects, not elsewhere classified	0.003	0.997	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.003	0.997	0.000
Z50.0 Cardiac rehabilitation	0.000	0.997	0.003
E70-E90 Metabolic disorders	0.003	0.997	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.003	0.997	0.000
D35.1 Parathyroid gland	0.003	0.997	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.003	0.997	0.000
E83.8 Other disorders of mineral metabolism	0.003	0.997	0.000
E83.2 Disorders of zinc metabolism	0.003	0.997	0.000
E83.0 Disorders of copper metabolism	0.003	0.997	0.000
E83.3 Disorders of phosphorus metabolism	0.003	0.997	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.003	0.997	0.000
E65-E68 Obesity and other hyperalimentation	0.003	0.997	0.000
E89.2 Postprocedural hypoparathyroidism	0.003	0.997	0.000
Z50.5 Speech therapy	0.000	0.997	0.002
N94.1 Dyspareunia	0.003	0.997	0.000
E89.0 Postprocedural hypothyroidism	0.003	0.997	0.000
R94.8 Abnormal results of function studies of other organs and systems	0.002	0.997	0.000
R94.7 Abnormal results of other endocrine function studies	0.002	0.997	0.000
R94.6 Abnormal results of thyroid function studies	0.002	0.997	0.000
R94.2 Abnormal results of pulmonary function studies	0.002	0.997	0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.002	0.997	0.000
R94.0 Abnormal results of function studies of central nervous system	0.002	0.997	0.000
E85 Amyloidosis	0.002	0.997	0.000
R73.9 Hyperglycaemia, unspecified	0.002	0.998	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.002	0.998	0.000
E46 Unspecified protein-energy malnutrition	0.002	0.998	0.000
E45 Retarded development following protein-energy malnutrition	0.002	0.998	0.000
E43 Unspecified severe protein-energy malnutrition	0.002	0.998	0.000
E42 Marasmic kwashiorkor	0.002	0.998	0.000
E41 Nutritional marasmus	0.002	0.998	0.000
E40 Kwashiorkor	0.002	0.998	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.002	0.998	0.000
E06 Thyroiditis	0.002	0.998	0.000
E73 Lactose intolerance	0.002	0.998	0.000
R94.4 Abnormal results of kidney function studies	0.002	0.998	0.000
E78.0 Pure hypercholesterolaemia	0.000	0.998	0.002
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.998	0.000
E00 Congenital iodine-deficiency syndrome	0.002	0.998	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.002	0.998	0.000
D35.2 Pituitary gland	0.002	0.998	0.000
E89.3 Postprocedural hypopituitarism	0.002	0.998	0.000
E04 Other non-toxic goitre	0.002	0.998	0.000
E65 Localised adiposity	0.002	0.998	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.002	0.998	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.002	0.998	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.002	0.998	0.000
E89.5 Postprocedural testicular hypofunction	0.002	0.998	0.000
E89.4 Postprocedural ovarian failure	0.002	0.998	0.000
E89.1 Postprocedural hypoinsulinaemia	0.002	0.998	0.000
E84 Cystic fibrosis	0.002	0.998	0.000
E79 Disorders of purine and pyrimidine metabolism	0.002	0.998	0.000
E77 Disorders of glycoprotein metabolism	0.002	0.998	0.000
E76 Disorders of glycosaminoglycan metabolism	0.002	0.998	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.002	0.998	0.000
E74 Other disorders of carbohydrate metabolism	0.002	0.998	0.000
E72 Other disorders of amino-acid metabolism	0.002	0.998	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.002	0.998	0.000
E70 Disorders of aromatic amino-acid metabolism	0.002	0.998	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.002	0.998	0.000
Y84.2 Radiological procedure and radiotherapy	0.002	0.998	0.000
E83.1 Disorders of iron metabolism	0.002	0.998	0.000
E04.1 Non-toxic single thyroid nodule	0.002	0.998	0.000
Z50.1 Other physical therapy	0.000	0.998	0.002
E05.8 Other thyrotoxicosis	0.002	0.998	0.000
E05.5 Thyroid crisis or storm	0.002	0.998	0.000
E05.4 Thyrotoxicosis factitia	0.002	0.998	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.002	0.998	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.002	0.998	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.002	0.998	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.002	0.998	0.000
E67 Other hyperalimentation	0.002	0.998	0.000
E68 Sequelae of hyperalimentation	0.002	0.998	0.000
E50-E64 Other nutritional deficiencies	0.002	0.998	0.000
D35.0 Adrenal gland	0.002	0.998	0.000
Z72.0 Tobacco use	0.000	0.998	0.002
E07 Other disorders of thyroid	0.002	0.998	0.000
E85.9 Amyloidosis, unspecified	0.002	0.998	0.000
Z50.8 Care involving use of rehabilitation procedures	0.000	0.998	0.002
E85.4 Organ-limited amyloidosis	0.002	0.998	0.000
Z01.5 Diagnostic skin and sensitisation tests	0.002	0.998	0.000
E88 Other metabolic disorders	0.002	0.998	0.000
E80.4 Gilbert's syndrome	0.002	0.998	0.000
O80.9 Single spontaneous delivery, unspecified	0.002	0.998	0.000
E73.9 Lactose intolerance, unspecified	0.002	0.998	0.000
Y84.8 Other medical procedures	0.002	0.998	0.000
E85.8 Other amyloidosis	0.002	0.998	0.000
E85.3 Secondary systemic amyloidosis	0.002	0.998	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.002	0.998	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.002	0.998	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.002	0.998	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.002	0.998	0.000
O80.0 Spontaneous vertex delivery	0.000	0.998	0.002
E06.3 Autoimmune thyroiditis	0.002	0.998	0.000
E44.1 Mild protein-energy malnutrition	0.002	0.998	0.000
E44.0 Moderate protein-energy malnutrition	0.002	0.998	0.000
Z46.6 Fitting and adjustment of urinary device	0.000	0.998	0.002
E73.8 Other lactose intolerance	0.002	0.998	0.000
E73.1 Secondary lactase deficiency	0.002	0.998	0.000
E73.0 Congenital lactase deficiency	0.002	0.998	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.002	0.998	0.000
E80.6 Other disorders of bilirubin metabolism	0.002	0.998	0.000
E80.5 Crigler-Najjar syndrome	0.002	0.998	0.000
E80.3 Defects of catalase and peroxydase	0.002	0.998	0.000
E80.2 Other porphyria	0.002	0.998	0.000
E80.1 Porphyria cutanea tarda	0.002	0.998	0.000
E80.0 Hereditary erythropoietic porphyria	0.002	0.998	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.002	0.998	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.002	0.998	0.000
E06.9 Thyroiditis, unspecified	0.002	0.998	0.000
E06.5 Other chronic thyroiditis	0.002	0.998	0.000
E06.4 Drug-induced thyroiditis	0.002	0.998	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.002	0.998	0.000
E06.1 Subacute thyroiditis	0.002	0.998	0.000
E06.0 Acute thyroiditis	0.002	0.998	0.000
M23.3 Other meniscus derangements	0.002	0.998	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.002	0.998	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.002	0.998	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.002	0.998	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.002	0.998	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.998	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.002	0.998	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.002	0.998	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.002	0.998	0.000
E04.8 Other specified non-toxic goitre	0.002	0.998	0.000
E04.0 Non-toxic diffuse goitre	0.002	0.998	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.002	0.998	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.002	0.998	0.000
E70.3 Albinism	0.002	0.998	0.000
E70.2 Disorders of tyrosine metabolism	0.002	0.998	0.000
E70.1 Other hyperphenylalaninaemias	0.002	0.998	0.000
E70.0 Classical phenylketonuria	0.002	0.998	0.000
E71.3 Disorders of fatty-acid metabolism	0.002	0.998	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.002	0.998	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.002	0.998	0.000
E71.0 Maple-syrup-urine disease	0.002	0.998	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.002	0.998	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.002	0.998	0.000
E72.5 Disorders of glycine metabolism	0.002	0.998	0.000
E72.4 Disorders of ornithine metabolism	0.002	0.998	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.002	0.998	0.000
E72.2 Disorders of urea cycle metabolism	0.002	0.998	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.002	0.998	0.000
E72.0 Disorders of amino-acid transport	0.002	0.998	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.002	0.998	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.002	0.998	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.002	0.998	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.002	0.998	0.000
E74.2 Disorders of galactose metabolism	0.002	0.998	0.000
E74.1 Disorders of fructose metabolism	0.002	0.998	0.000
E74.0 Glycogen storage disease	0.002	0.998	0.000
E75.6 Lipid storage disorder, unspecified	0.002	0.998	0.000
E75.5 Other lipid storage disorders	0.002	0.998	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.002	0.998	0.000
E75.3 Sphingolipidosis, unspecified	0.002	0.998	0.000
E75.2 Other sphingolipidosis	0.002	0.998	0.000
E75.1 Other gangliosidosis	0.002	0.998	0.000
E75.0 GM2 gangliosidosis	0.002	0.998	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.002	0.998	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.002	0.998	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.002	0.998	0.000
E76.2 Other mucopolysaccharidoses	0.002	0.998	0.000
E76.1 Mucopolysaccharidosis, type II	0.002	0.998	0.000
E76.0 Mucopolysaccharidosis, type I	0.002	0.998	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.002	0.998	0.000
E77.8 Other disorders of glycoprotein metabolism	0.002	0.998	0.000
E77.1 Defects in glycoprotein degradation	0.002	0.998	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.002	0.998	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.002	0.998	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.002	0.998	0.000
E79.1 Lesch-Nyhan syndrome	0.002	0.998	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.002	0.998	0.000
E84.9 Cystic fibrosis, unspecified	0.002	0.998	0.000
E84.8 Cystic fibrosis with other manifestations	0.002	0.998	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.002	0.998	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.002	0.998	0.000
G93.8 Other specified disorders of brain	0.002	0.998	0.000
H90.2 Conductive hearing loss, unspecified	0.002	0.998	0.000
A41 Other septicaemia	0.000	0.998	0.002
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
E04.9 Non-toxic goitre, unspecified	0.002	0.998	0.000
A41.8 Other specified septicaemia	0.000	0.998	0.002
D35.9 Endocrine gland, unspecified	0.002	0.998	0.000
D35.8 Pluriglandular involvement	0.002	0.998	0.000
D35.7 Other specified endocrine glands	0.002	0.998	0.000
D35.6 Aortic body and other paraganglia	0.002	0.998	0.000
D35.5 Carotid body	0.002	0.998	0.000
D35.4 Pineal gland	0.002	0.998	0.000
D35.3 Craniopharyngeal duct	0.002	0.998	0.000
E67.8 Other specified hyperalimentation	0.002	0.998	0.000
E67.3 Hypervitaminosis D	0.002	0.998	0.000
E67.2 Megavitamin-B6 syndrome	0.002	0.998	0.000
E67.1 Hypercarotenaemia	0.002	0.998	0.000
E67.0 Hypervitaminosis A	0.002	0.998	0.000
Z01.8 Other specified special examinations	0.002	0.998	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.002	0.998	0.000
E63 Other nutritional deficiencies	0.002	0.998	0.000
E56 Other vitamin deficiencies	0.002	0.998	0.000
E51 Thiamine deficiency	0.002	0.998	0.000
E50 Vitamin A deficiency	0.002	0.998	0.000
E60 Dietary zinc deficiency	0.002	0.998	0.000
E59 Dietary selenium deficiency	0.002	0.998	0.000
E58 Dietary calcium deficiency	0.002	0.998	0.000
E54 Ascorbic acid deficiency	0.002	0.998	0.000
E52 Niacin deficiency [pellagra]	0.002	0.998	0.000
E07.8 Other specified disorders of thyroid	0.002	0.998	0.000
E07.1 Dyshormogenetic goitre	0.002	0.998	0.000
E07.0 Hypersecretion of calcitonin	0.002	0.998	0.000
G93.4 Encephalopathy, unspecified	0.002	0.998	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.002	0.998	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.002	0.998	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
H90 Conductive and sensorineural hearing loss	0.002	0.998	0.000
E88.9 Metabolic disorder, unspecified	0.002	0.998	0.000
E88.8 Other specified metabolic disorders	0.002	0.998	0.000
E88.3 Tumour lysis syndrome	0.002	0.998	0.000
E88.2 Lipomatosis, not elsewhere classified	0.002	0.998	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.002	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
K22.4 Dyskinesia of oesophagus	0.002	0.998	0.000
I50.9 Heart failure, unspecified	0.000	0.998	0.002
E61 Deficiency of other nutrient elements	0.002	0.998	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.000	0.998	0.002
H90.5 Sensorineural hearing loss, unspecified	0.002	0.998	0.000
K76.8 Other specified diseases of liver	0.000	0.998	0.002
Y84.4 Aspiration of fluid	0.002	0.998	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
F10.2 Dependence syndrome	0.000	0.998	0.002
Y84.1 Kidney dialysis	0.002	0.998	0.000
R73 Elevated blood glucose level	0.002	0.998	0.000
M23.37 Other meniscus derangements-Capsular lig	0.002	0.998	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.002	0.998	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.002	0.998	0.000
S61.1 Open wound of finger(s) with damage to nail	0.000	0.998	0.002
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
A41.4 Septicaemia due to anaerobes	0.000	0.998	0.002
A41.3 Septicaemia due to Haemophilus influenzae	0.000	0.998	0.002
A41.2 Septicaemia due to unspecified staphylococcus	0.000	0.998	0.002
Z85.4 Personal history of malignant neoplasm of genital organs	0.002	0.998	0.000
E66 Obesity	0.002	0.998	0.000
E07.9 Disorder of thyroid, unspecified	0.001	0.998	0.000
K35 Acute appendicitis	0.002	0.998	0.000
O46.9 Antepartum haemorrhage, unspecified	0.002	0.998	0.000
E03 Other hypothyroidism	0.002	0.998	0.000
O80 Single spontaneous delivery	0.001	0.998	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.001	0.998	0.000
E50.9 Vitamin A deficiency, unspecified	0.001	0.998	0.000
E50.8 Other manifestations of vitamin A deficiency	0.001	0.998	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.001	0.998	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.001	0.998	0.000
E50.5 Vitamin A deficiency with night blindness	0.001	0.998	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.001	0.998	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.001	0.998	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.001	0.998	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.001	0.998	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.001	0.998	0.000
E51.9 Thiamine deficiency, unspecified	0.001	0.998	0.000
E51.8 Other manifestations of thiamine deficiency	0.001	0.998	0.000
E51.2 Wernicke's encephalopathy	0.001	0.998	0.000
E51.1 Beriberi	0.001	0.998	0.000
E56.9 Vitamin deficiency, unspecified	0.001	0.998	0.000
E56.8 Deficiency of other vitamins	0.001	0.998	0.000
E56.1 Deficiency of vitamin K	0.001	0.998	0.000
E56.0 Deficiency of vitamin E	0.001	0.998	0.000
E63.9 Nutritional deficiency, unspecified	0.001	0.998	0.000
E63.8 Other specified nutritional deficiencies	0.001	0.998	0.000
E63.1 Imbalance of constituents of food intake	0.001	0.998	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.001	0.998	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.001	0.998	0.000
E64.8 Sequelae of other nutritional deficiencies	0.001	0.998	0.000
E64.3 Sequelae of rickets	0.001	0.998	0.000
E64.2 Sequelae of vitamin C deficiency	0.001	0.998	0.000
E64.1 Sequelae of vitamin A deficiency	0.001	0.998	0.000
E64.0 Sequelae of protein-energy malnutrition	0.001	0.998	0.000
E55 Vitamin D deficiency	0.001	0.998	0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.000	0.998	0.002
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.998	0.002
H90.0 Conductive hearing loss, bilateral	0.001	0.998	0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.002	0.998	0.000
R70.0 Elevated erythrocyte sedimentation rate	0.002	0.998	0.000
R94.3 Abnormal results of cardiovascular function studies	0.001	0.998	0.001
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
Y84.9 Medical procedure, unspecified	0.001	0.998	0.000
Y84.7 Blood-sampling	0.001	0.998	0.000
Y84.5 Insertion of gastric or duodenal sound	0.001	0.998	0.000
Y84.3 Shock therapy	0.001	0.998	0.000
T66-T78 Other and unspecified effects of external causes	0.002	0.998	0.000
E66.0 Obesity due to excess calories	0.001	0.998	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.001	0.998	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.001	0.998	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.001	0.998	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.001	0.998	0.000
O32.4 Maternal care for high head at term	0.002	0.998	0.000
E53 Deficiency of other B group vitamins	0.001	0.998	0.000
E03.8 Other specified hypothyroidism	0.001	0.998	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.001	0.998	0.000
H90.3 Sensorineural hearing loss, bilateral	0.001	0.998	0.000
K35.3 Acute appendicitis with localized peritonitis	0.001	0.998	0.000
O32.0 Maternal care for unstable lie	0.002	0.998	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.002	0.998	0.000
N39.3 Stress incontinence	0.000	0.998	0.002
S61.9 Open wound of wrist and hand, part unspecified	0.000	0.998	0.002
E61.9 Deficiency of nutrient element, unspecified	0.001	0.998	0.000
E61.8 Deficiency of other specified nutrient elements	0.001	0.998	0.000
E61.7 Deficiency of multiple nutrient elements	0.001	0.998	0.000
E61.6 Vanadium deficiency	0.001	0.998	0.000
E61.5 Molybdenum deficiency	0.001	0.998	0.000
E61.4 Chromium deficiency	0.001	0.998	0.000
E61.3 Manganese deficiency	0.001	0.998	0.000
E61.2 Magnesium deficiency	0.001	0.998	0.000
E61.0 Copper deficiency	0.001	0.998	0.000
O80.8 Other single spontaneous delivery	0.001	0.998	0.000
R73.0 Abnormal glucose tolerance test	0.001	0.998	0.000
Y84.6 Urinary catheterisation	0.001	0.998	0.000
K20 Oesophagitis	0.002	0.998	0.000
A41.9 Septicaemia, unspecified	0.000	0.998	0.002
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.001	0.998	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
Z86.1 Personal history of infectious and parasitic diseases	0.002	0.998	0.000
G93 Other disorders of brain	0.002	0.998	0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.002	0.998	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.001	0.998	0.000
I84.1 Internal haemorrhoids with other complications	0.002	0.998	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.001	0.998	0.000
Y42.9 Other and unspecified hormone antagonists	0.001	0.998	0.000
Y42.4 Oral contraceptives	0.001	0.998	0.000
Y42.2 Antithyroid drugs	0.001	0.998	0.000
Y42.1 Thyroid hormones and substitutes	0.001	0.998	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.001	0.998	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.001	0.999	0.000
E66.1 Drug-induced obesity	0.001	0.999	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.001	0.999	0.000
Z01.9 Special examination, unspecified	0.001	0.999	0.000
E03.5 Myxoedema coma	0.001	0.999	0.000
E03.4 Atrophy of thyroid (acquired)	0.001	0.999	0.000
E03.3 Postinfectious hypothyroidism	0.001	0.999	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.001	0.999	0.000
E03.1 Congenital hypothyroidism without goitre	0.001	0.999	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.001	0.999	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.001	0.999	0.000
O80.1 Spontaneous breech delivery	0.001	0.999	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.001	0.999	0.000
A41.1 Septicaemia due to other specified staphylococcus	0.000	0.999	0.001
C85.1 B-cell lymphoma, unspecified	0.000	0.999	0.001
E04.2 Non-toxic multinodular goitre	0.001	0.999	0.000
F10.0 Acute intoxication	0.000	0.999	0.001
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.001	0.999	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.001	0.999	0.000
E55.0 Rickets, active	0.001	0.999	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.001	0.999	0.000
L98.7 Excessive and redundant skin and subcutaneous tissue	0.000	0.999	0.001
L98.6 Other infiltrative disorders of skin and subcutaneous tissue	0.000	0.999	0.001
L98.5 Mucinosis of skin	0.000	0.999	0.001
L98.3 Eosinophilic cellulitis [Wells]	0.000	0.999	0.001
L98.2 Febrile neutrophilic dermatosis [Sweet]	0.000	0.999	0.001
L98.1 Factitial dermatitis	0.000	0.999	0.001
O03.9 Complete or unspecified, without complication	0.001	0.999	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.001	0.999	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.001	0.999	0.000
E53.9 Vitamin B deficiency, unspecified	0.001	0.999	0.000
E53.1 Pyridoxine deficiency	0.001	0.999	0.000
E53.0 Riboflavin deficiency	0.001	0.999	0.000
N94.6 Dysmenorrhoea, unspecified	0.001	0.999	0.000
O32.2 Maternal care for transverse and oblique lie	0.001	0.999	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.001	0.999	0.000
T75 Effects of other external causes	0.001	0.999	0.000
T74 Maltreatment syndromes	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations