TreeWAS – Variant ID: rs1325765

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.006	0.994
M20-M25 Other joint disorders	0.006	0.994
M15-M19 Arthrosis	0.006	0.994
M45-M49 Spondylopathies	0.005	0.995
M05-M14 Inflammatory polyarthropathies	0.005	0.995
M25 Other joint disorders, not elsewhere classified	0.005	0.995
M20 Acquired deformities of fingers and toes	0.005	0.995
M17 Gonarthrosis [arthrosis of knee]	0.005	0.995
M65-M68 Disorders of synovium and tendon	0.005	0.995
M50-M54 Other dorsopathies	0.005	0.995
M23 Internal derangement of knee	0.005	0.995
M40-M43 Deforming dorsopathies	0.005	0.995
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.005	0.995
M91-M94 Chondropathies	0.005	0.995
M60-M63 Disorders of muscles	0.005	0.995
M70-M79 Other soft tissue disorders	0.005	0.995
M00-M03 Infectious arthropathies	0.005	0.995
M16 Coxarthrosis [arthrosis of hip]	0.005	0.995
M80-M85 Disorders of bone density and structure	0.005	0.995
M86-M90 Other osteopathies	0.005	0.995
M24 Other specific joint derangements	0.004	0.995
M31 Other necrotising vasculopathies	0.004	0.995
M13 Other arthritis	0.004	0.995
# Top node	0.005	0.995
M34 Systemic sclerosis	0.004	0.995
M18 Arthrosis of first carpometacarpal joint	0.004	0.995
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.004	0.995
M33 Dermatopolymyositis	0.004	0.995
M32 Systemic lupus erythematosus	0.004	0.995
M30 Polyarteritis nodosa and related conditions	0.004	0.995
M47 Spondylosis	0.004	0.995
M17.1 Other primary gonarthrosis	0.004	0.995
M22 Disorders of patella	0.004	0.995
M19 Other arthrosis	0.004	0.995
M35 Other systemic involvement of connective tissue	0.004	0.995
Chapter VII Diseases of the eye and adnexa	0.004	0.995
M15 Polyarthrosis	0.004	0.996
M21 Other acquired deformities of limbs	0.004	0.996
Chapter II Neoplasms	0.004	0.996
M25.5 Pain in joint	0.004	0.996
Chapter XXI Factors influencing health status and contact with health services	0.004	0.996
M20.1 Hallux valgus (acquired)	0.004	0.996
M10 Gout	0.004	0.996
M48 Other spondylopathies	0.004	0.996
M25.7 Osteophyte	0.004	0.996
M46 Other inflammatory spondylopathies	0.004	0.996
M45 Ankylosing spondylitis	0.004	0.996
M05 Seropositive rheumatoid arthritis	0.004	0.996
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.004	0.996
M11 Other crystal arthropathies	0.004	0.996
H25-H28 Disorders of lens	0.004	0.996
M14 Arthropathies in other diseases classified elsewhere	0.004	0.996
M12 Other specific arthropathies	0.004	0.996
M09 Juvenile arthritis in diseases classified elsewhere	0.004	0.996
M08 Juvenile arthritis	0.004	0.996
M49 Spondylopathies in diseases classified elsewhere	0.004	0.996
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.004	0.996
M07 Psoriatic and enteropathic arthropathies	0.004	0.996
M06 Other rheumatoid arthritis	0.004	0.996
M51 Other intervertebral disk disorders	0.004	0.996
M17.0 Primary gonarthrosis, bilateral	0.004	0.996
M25.4 Effusion of joint	0.004	0.996
M65 Synovitis and tenosynovitis	0.004	0.996
M13.9 Arthritis, unspecified	0.004	0.996
Z40-Z54 Persons encountering health services for specific procedures and health care	0.004	0.996
M25.8 Other specified joint disorders	0.004	0.996
M20.4 Other hammer toe(s) (acquired)	0.004	0.996
M25.6 Stiffness of joint, not elsewhere classified	0.004	0.996
M20.5 Other deformities of toe(s) (acquired)	0.004	0.996
M25.9 Joint disorder, unspecified	0.004	0.996
M23.2 Derangement of meniscus due to old tear or injury	0.004	0.996
M25.0 Haemarthrosis	0.004	0.996
M20.6 Acquired deformity of toe(s), unspecified	0.004	0.996
M25.2 Flail joint	0.004	0.996
M25.1 Fistula of joint	0.004	0.996
M20.0 Deformity of finger(s)	0.004	0.996
M20.3 Other deformity of hallux (acquired)	0.004	0.996
M23.3 Other meniscus derangements	0.004	0.996
M67 Other disorders of synovium and tendon	0.004	0.996
M17.5 Other secondary gonarthrosis	0.004	0.996
M17.3 Other posttraumatic gonarthrosis	0.004	0.996
M23.8 Other internal derangements of knee	0.004	0.996
M50 Cervical disk disorders	0.004	0.996
M17.4 Other secondary gonarthrosis, bilateral	0.004	0.996
M17.2 Posttraumatic gonarthrosis, bilateral	0.004	0.996
M53 Other dorsopathies, not elsewhere classified	0.004	0.996
Chapter VI Diseases of the nervous system	0.004	0.996
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.004	0.996
M16.9 Coxarthrosis, unspecified	0.004	0.996
M23.5 Chronic instability of knee	0.004	0.996
M23.4 Loose body in knee	0.004	0.996
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.004	0.996
M20.2 Hallux rigidus	0.004	0.996
M23.9 Internal derangement of knee, unspecified	0.004	0.996
M23.6 Other spontaneous disruption of ligament(s) of knee	0.004	0.996
M23.1 Discoid meniscus (congenital)	0.004	0.996
M23.0 Cystic meniscus	0.004	0.996
M41 Scoliosis	0.004	0.996
M54 Dorsalgia	0.004	0.996
M66 Spontaneous rupture of synovium and tendon	0.004	0.996
M25.3 Other instability of joint	0.004	0.996
M47.8 Other spondylosis	0.004	0.996
M43 Other deforming dorsopathies	0.004	0.996
M42 Spinal osteochondrosis	0.004	0.996
M40 Kyphosis and lordosis	0.004	0.996
M62 Other disorders of muscle	0.004	0.996
M77 Other enthesopathies	0.004	0.996
M94 Other disorders of cartilage	0.004	0.996
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.004	0.996
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.004	0.996
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.004	0.996
M16.0 Primary coxarthrosis, bilateral	0.004	0.996
M60 Myositis	0.004	0.996
M79 Other soft tissue disorders, not elsewhere classified	0.004	0.996
M70 Soft tissue disorders related to use, overuse and pressure	0.004	0.996
M93 Other osteochondropathies	0.004	0.996
M99 Biomechanical lesions, not elsewhere classified	0.004	0.996
M47.9 Spondylosis, unspecified	0.004	0.996
M00 Pyogenic arthritis	0.004	0.996
M63 Disorders of muscle in diseases classified elsewhere	0.004	0.996
M61 Calcification and ossification of muscle	0.004	0.996
M76 Enthesopathies of lower limb, excluding foot	0.004	0.996
M92 Other juvenile osteochondrosis	0.004	0.996
M91 Juvenile osteochondrosis of hip and pelvis	0.004	0.996
M17.9 Gonarthrosis, unspecified	0.004	0.996
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.004	0.996
M02 Reactive arthropathies	0.004	0.996
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.004	0.996
M75 Shoulder lesions	0.004	0.996
M73 Soft tissue disorders in diseases classified elsewhere	0.004	0.996
C43-C44 Melanoma and other malignant neoplasms of skin	0.004	0.996
Chapter XX External causes of morbidity and mortality	0.004	0.996
Chapter XV Pregnancy, childbirth and the puerperium	0.004	0.996
Z92 Personal history of medical treatment	0.004	0.996
H26 Other cataract	0.004	0.996
M80 Osteoporosis with pathological fracture	0.003	0.996
M16.7 Other secondary coxarthrosis	0.003	0.996
M16.3 Other dysplastic coxarthrosis	0.003	0.996
M71 Other bursopathies	0.003	0.996
M85 Other disorders of bone density and structure	0.003	0.996
M16.6 Other secondary coxarthrosis, bilateral	0.003	0.996
M16.5 Other posttraumatic coxarthrosis	0.003	0.996
M16.4 Posttraumatic coxarthrosis, bilateral	0.003	0.996
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.003	0.996
M16.1 Other primary coxarthrosis	0.003	0.996
M87 Osteonecrosis	0.003	0.996
H53-H54 Visual disturbances and blindness	0.004	0.996
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.003	0.996
M24.1 Other articular cartilage disorders	0.003	0.996
M84 Disorders of continuity of bone	0.003	0.996
M83 Adult osteomalacia	0.003	0.996
M90 Osteopathies in diseases classified elsewhere	0.003	0.996
M88 Paget's disease of bone [osteitis deformans]	0.003	0.996
M72 Fibroblastic disorders	0.003	0.996
M24.8 Other specific joint derangements, not elsewhere classified	0.003	0.996
M24.2 Disorder of ligament	0.003	0.996
M24.0 Loose body in joint	0.003	0.996
M31.6 Other giant cell arteritis	0.003	0.996
Z96 Presence of other functional implants	0.004	0.996
M19.0 Primary arthrosis of other joints	0.003	0.996
M24.6 Ankylosis of joint	0.003	0.996
M24.5 Contracture of joint	0.003	0.996
M31.3 Wegener's granulomatosis	0.003	0.996
D10-D36 Benign neoplasms	0.004	0.996
C51-C58 Malignant neoplasms of female genital organs	0.003	0.996
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.003	0.996
M13.0 Polyarthritis, unspecified	0.003	0.996
M24.9 Joint derangement, unspecified	0.003	0.996
M24.7 Protrusio acetabuli	0.003	0.996
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.003	0.996
M31.9 Necrotising vasculopathy, unspecified	0.003	0.996
M31.8 Other specified necrotising vasculopathies	0.003	0.996
M31.7 Microscopic polyangiitis	0.003	0.996
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.003	0.996
M31.4 Aortic arch syndrome [Takayasu]	0.003	0.996
M31.2 Lethal midline granuloma	0.003	0.996
M31.1 Thrombotic microangiopathy	0.003	0.996
M31.0 Hypersensitivity angiitis	0.003	0.996
M82 Osteoporosis in diseases classified elsewhere	0.003	0.996
M13.8 Other specified arthritis	0.003	0.996
M13.1 Monoarthritis, not elsewhere classified	0.003	0.996
M18.1 Other primary arthrosis of first carpometacarpal joint	0.003	0.996
M47.2 Other spondylosis with radiculopathy	0.003	0.996
M89 Other disorders of bone	0.003	0.996
Z90 Acquired absence of organs, not elsewhere classified	0.004	0.996
M25.55 Pain in joint (Pelvic region and thigh)	0.003	0.996
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.003	0.996
M22.4 Chondromalacia patellae	0.003	0.996
M34.9 Systemic sclerosis, unspecified	0.003	0.996
M34.8 Other forms of systemic sclerosis	0.003	0.996
M34.2 Systemic sclerosis induced by drugs and chemicals	0.003	0.996
M34.1 CR(E)ST syndrome	0.003	0.996
M34.0 Progressive systemic sclerosis	0.003	0.996
M35.0 Sicca syndrome [Sjogren]	0.003	0.996
M47.1 Other spondylosis with myelopathy	0.003	0.996
H55-H59 Other disorders of eye and adnexa	0.003	0.996
H10-H13 Disorders of conjunctiva	0.003	0.996
Chapter XVI Certain conditions originating in the perinatal period	0.003	0.996
Chapter VIII Diseases of the ear and mastoid process	0.003	0.996
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.003	0.996
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.003	0.996
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.003	0.996
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.003	0.996
M19.9 Arthrosis, unspecified	0.003	0.996
M22.2 Patellofemoral disorders	0.003	0.996
M30.8 Other conditions related to polyarteritis nodosa	0.003	0.996
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.003	0.996
M30.2 Juvenile polyarteritis	0.003	0.996
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.003	0.996
M30.0 Polyarteritis nodosa	0.003	0.996
M32.9 Systemic lupus erythematosus, unspecified	0.003	0.996
M32.8 Other forms of systemic lupus erythematosus	0.003	0.996
M32.1 Systemic lupus erythematosus with organ or system involvement	0.003	0.996
M32.0 Drug-induced systemic lupus erythematosus	0.003	0.996
M33.9 Dermatopolymyositis, unspecified	0.003	0.996
M33.2 Polymyositis	0.003	0.996
M33.1 Other dermatomyositis	0.003	0.996
M33.0 Juvenile dermatomyositis	0.003	0.996
M47.0 Anterior spinal and vertebral artery compression syndromes	0.003	0.996
H25 Senile cataract	0.003	0.996
M86 Osteomyelitis	0.003	0.996
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.003	0.996
H30-H36 Disorders of choroid and retina	0.003	0.996
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.003	0.996
M22.3 Other derangements of patella	0.003	0.996
M24.4 Recurrent dislocation and subluxation of joint	0.003	0.996
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.003	0.996
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.003	0.996
M36.3 Arthropathy in other blood disorders	0.003	0.996
M36.2 Haemophilic arthropathy	0.003	0.996
M36.1 Arthropathy in neoplastic disease	0.003	0.996
M36.0 Dermato(poly)myositis in neoplastic disease	0.003	0.996
T36-T50 Poisoning by drugs, medicaments and biological substances	0.003	0.996
M22.1 Recurrent subluxation of patella	0.003	0.996
M22.9 Disorder of patella, unspecified	0.003	0.996
M22.0 Recurrent dislocation of patella	0.003	0.996
M35.8 Other specified systemic involvement of connective tissue	0.003	0.996
M35.7 Hypermobility syndrome	0.003	0.996
M35.4 Diffuse (eosinophilic) fasciitis	0.003	0.996
M35.2 Behcet's disease	0.003	0.996
M35.1 Other overlap syndromes	0.003	0.996
M81 Osteoporosis without pathological fracture	0.003	0.996
Z51 Other medical care	0.003	0.996
Z85 Personal history of malignant neoplasm	0.003	0.996
D37-D48 Neoplasms of uncertain or unknown behaviour	0.003	0.996
C50-C50 Malignant neoplasm of breast	0.003	0.996
H46-H48 Disorders of optic nerve and visual pathways	0.003	0.996
Chapter XXII Codes for special purposes	0.003	0.996
M10.9 Gout, unspecified	0.003	0.996
M19.8 Other specified arthrosis	0.003	0.996
M19.2 Other secondary arthrosis	0.003	0.996
M35.9 Systemic involvement of connective tissue, unspecified	0.003	0.996
M35.6 Relapsing panniculitis [Weber-Christian]	0.003	0.996
M35.5 Multifocal fibrosclerosis	0.003	0.996
M25.56 Pain in joint (Lower leg)	0.003	0.996
M25.51 Pain in joint (Shoulder region)	0.003	0.996
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.003	0.996
H40-H42 Glaucoma	0.003	0.996
M13.99 Arthritis, unspecified (Site unspecified)	0.003	0.997
Z91 Personal history of risk-factors, not elsewhere classified	0.003	0.997
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.003	0.997
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.003	0.997
H43-H45 Disorders of vitreous body and globe	0.003	0.997
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.003	0.997
M15.9 Polyarthrosis, unspecified	0.003	0.997
M15.0 Primary generalised (osteo)arthrosis	0.003	0.997
M15.8 Other polyarthrosis	0.003	0.997
M15.4 Erosive (osteo)arthrosis	0.003	0.997
M15.3 Secondary multiple arthrosis	0.003	0.997
M15.2 Bouchard's nodes (with arthropathy)	0.003	0.997
M15.1 Heberden's nodes (with arthropathy)	0.003	0.997
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.003	0.997
C15-C26 Malignant neoplasms of digestive organs	0.003	0.997
S60-S69 Injuries to the wrist and hand	0.003	0.997
H26.9 Cataract, unspecified	0.003	0.997
M19.1 Posttraumatic arthrosis of other joints	0.003	0.997
M21.3 Wrist or foot drop (acquired)	0.003	0.997
M21.2 Flexion deformity	0.003	0.997
M21.0 Valgus deformity, not elsewhere classified	0.003	0.997
M51.2 Other specified intervertebral disk displacement	0.003	0.997
M25.53 Pain in joint (Forearm)	0.003	0.997
M25.50 Pain in joint (Multiple sites)	0.003	0.997
M21.9 Acquired deformity of limb, unspecified	0.003	0.997
M21.8 Other specified acquired deformities of limbs	0.003	0.997
M21.7 Unequal limb length (acquired)	0.003	0.997
M21.4 Flat foot [pes planus] (acquired)	0.003	0.997
M22.8 Other disorders of patella	0.003	0.997
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.003	0.997
C64-C68 Malignant neoplasms of urinary tract	0.003	0.997
C40-C41 Malignant neoplasms of bone and articular cartilage	0.003	0.997
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.003	0.997
M25.59 Pain in joint (Site unspecified)	0.003	0.997
M25.54 Pain in joint (Hand)	0.003	0.997
M25.58 Pain in joint (Other)	0.003	0.997
M25.52 Pain in joint (Upper arm)	0.003	0.997
M35.3 Polymyalgia rheumatica	0.003	0.997
M48.0 Spinal stenosis	0.003	0.997
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.003	0.997
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.003	0.997
Z46 Fitting and adjustment of other devices	0.003	0.997
G40-G47 Episodic and paroxysmal disorders	0.003	0.997
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.003	0.997
S20-S29 Injuries to the thorax	0.003	0.997
M25.77 Osteophyte (Ankle and foot)	0.003	0.997
M21.1 Varus deformity, not elsewhere classified	0.003	0.997
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.003	0.997
M25.57 Pain in joint (Ankle and foot)	0.003	0.997
M25.76 Osteophyte (Lower leg)	0.003	0.997
M10.4 Other secondary gout	0.003	0.997
M10.3 Gout due to impairment of renal function	0.003	0.997
M10.2 Drug-induced gout	0.003	0.997
M10.1 Lead-induced gout	0.003	0.997
M10.0 Idiopathic gout	0.003	0.997
M21.6 Other acquired deformities of ankle and foot	0.003	0.997
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.003	0.997
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.003	0.997
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.003	0.997
S40-S49 Injuries to the shoulder and upper arm	0.003	0.997
M46.9 Inflammatory spondylopathy, unspecified	0.003	0.997
M48.5 Collapsed vertebra, not elsewhere classified	0.003	0.997
D00-D09 In situ neoplasms	0.003	0.997
S90-S99 Injuries to the ankle and foot	0.003	0.997
M48.9 Spondylopathy, unspecified	0.003	0.997
M48.8 Other specified spondylopathies	0.003	0.997
M48.4 Fatigue fracture of vertebra	0.003	0.997
M48.3 Traumatic spondylopathy	0.003	0.997
M48.2 Kissing spine	0.003	0.997
M48.1 Ankylosing hyperostosis [Forestier]	0.003	0.997
Z93 Artificial opening status	0.003	0.997
T66-T78 Other and unspecified effects of external causes	0.003	0.997
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.003	0.997
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.003	0.997
Chapter XII Diseases of the skin and subcutaneous tissue	0.003	0.997
Chapter V Mental and behavioural disorders	0.003	0.997
Chapter I Certain infectious and parasitic diseases	0.003	0.997
M25.78 Osteophyte (Other)	0.003	0.997
M25.75 Osteophyte (Pelvic region and thigh)	0.003	0.997
M25.74 Osteophyte (Hand)	0.003	0.997
M25.71 Osteophyte (Shoulder region)	0.003	0.997
M05.9 Seropositive rheumatoid arthritis, unspecified	0.003	0.997
M65.9 Synovitis and tenosynovitis, unspecified	0.003	0.997
Z96.6 Presence of orthopaedic joint implants	0.003	0.997
Z97 Presence of other devices	0.003	0.997
M25.79 Osteophyte (Site unspecified)	0.003	0.997
M25.73 Osteophyte (Forearm)	0.003	0.997
M25.72 Osteophyte (Upper arm)	0.003	0.997
M25.70 Osteophyte (Multiple sites)	0.003	0.997
M45.X9 Ankylosing spondylitis (Site unspecified)	0.003	0.997
M46.8 Other specified inflammatory spondylopathies	0.003	0.997
M46.5 Other infective spondylopathies	0.003	0.997
M46.4 Discitis, unspecified	0.003	0.997
M46.3 Infection of intervertebral disk (pyogenic)	0.003	0.997
M46.2 Osteomyelitis of vertebra	0.003	0.997
M46.1 Sacro-iliitis, not elsewhere classified	0.003	0.997
M46.0 Spinal enthesopathy	0.003	0.997
C44 Other malignant neoplasms of skin	0.003	0.997
Z48 Other surgical follow-up care	0.003	0.997
S10-S19 Injuries to the neck	0.003	0.997
M13.90 Arthritis, unspecified (Multiple sites)	0.003	0.997
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.003	0.997
M11.2 Other chondrocalcinosis	0.003	0.997
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.003	0.997
M45.X6 Ankylosing spondylitis (Lumbar region)	0.003	0.997
M45.X2 Ankylosing spondylitis (Cervical region)	0.003	0.997
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.003	0.997
Z45 Adjustment and management of implanted device	0.003	0.997
Z89 Acquired absence of limb	0.003	0.997
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.003	0.997
T00-T07 Injuries involving multiple body regions	0.003	0.997
S80-S89 Injuries to the knee and lower leg	0.003	0.997
M13.96 Arthritis, unspecified (Lower leg)	0.003	0.997
M25.46 Effusion of joint (Lower leg)	0.003	0.997
M05.8 Other seropositive rheumatoid arthritis	0.003	0.997
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.003	0.997
M05.2 Rheumatoid vasculitis	0.003	0.997
M05.1 Rheumatoid lung disease	0.003	0.997
M05.0 Felty's syndrome	0.003	0.997
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.003	0.997
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.003	0.997
M45.X4 Ankylosing spondylitis (Thoracic region)	0.003	0.997
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.003	0.997
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.003	0.997
M65.3 Trigger finger	0.003	0.997
H27 Other disorders of lens	0.003	0.997
D60-D64 Aplastic and other anaemias	0.003	0.997
T33-T35 Frostbite	0.003	0.997
T26-T28 Burns and corrosions confined to eye and internal organs	0.003	0.997
M13.97 Arthritis, unspecified (Ankle and foot)	0.003	0.997
M13.94 Arthritis, unspecified (Hand)	0.003	0.997
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.003	0.997
M08.0 Juvenile rheumatoid arthritis	0.003	0.997
M11.9 Crystal arthropathy, unspecified	0.003	0.997
M11.8 Other specified crystal arthropathies	0.003	0.997
M11.1 Familial chondrocalcinosis	0.003	0.997
M11.0 Hydroxyapatite deposition disease	0.003	0.997
M12.8 Other specific arthropathies, not elsewhere classified	0.003	0.997
M12.5 Traumatic arthropathy	0.003	0.997
M12.4 Intermittent hydrarthrosis	0.003	0.997
M12.3 Palindromic rheumatism	0.003	0.997
M12.2 Villonodular synovitis (pigmented)	0.003	0.997
M12.1 Kaschin-Beck disease	0.003	0.997
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.003	0.997
M14.8 Arthropathies in other specified diseases classified elsewhere	0.003	0.997
M14.6 Neuropathic arthropathy	0.003	0.997
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.003	0.997
M14.4 Arthropathy in amyloidosis	0.003	0.997
M14.3 Lipoid dermatoarthritis	0.003	0.997
M14.2 Diabetic arthropathy	0.003	0.997
M14.1 Crystal arthropathy in other metabolic disorders	0.003	0.997
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.003	0.997
M49.8 Spondylopathy in other diseases classified elsewhere	0.003	0.997
M49.5 Collapsed vertebra in diseases classified elsewhere	0.003	0.997
M49.4 Neuropathic spondylopathy	0.003	0.997
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.003	0.997
M49.2 Enterobacterial spondylitis	0.003	0.997
M49.1 Brucella spondylitis	0.003	0.997
M49.0 Tuberculosis of spine	0.003	0.997
Z92.2 Personal history of long-term (current) use of other medicaments	0.003	0.997
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.003	0.997
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.003	0.997
Z95 Presence of cardiac and vascular implants and grafts	0.003	0.997
Z87 Personal history of other diseases and conditions	0.003	0.997
Z84 Family history of other conditions	0.003	0.997
Z81 Family history of mental and behavioural disorders	0.003	0.997
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.003	0.997
T15-T19 Effects of foreign body entering through natural orifice	0.003	0.997
S50-S59 Injuries to the elbow and forearm	0.003	0.997
M06.0 Seronegative rheumatoid arthritis	0.003	0.997
M08.9 Juvenile arthritis, unspecified	0.003	0.997
M08.8 Other juvenile arthritis	0.003	0.997
M08.4 Pauciarticular juvenile arthritis	0.003	0.997
M08.3 Juvenile polyarthritis (seronegative)	0.003	0.997
M08.2 Juvenile arthritis with systemic onset	0.003	0.997
M08.1 Juvenile ankylosing spondylitis	0.003	0.997
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.003	0.997
M09.2 Juvenile arthritis in ulcerative colitis	0.003	0.997
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.003	0.997
M09.0 Juvenile arthritis in psoriasis	0.003	0.997
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.003	0.997
Z41 Procedures for purposes other than remedying health state	0.003	0.997
Z40 Prophylactic surgery	0.003	0.997
Z94 Transplanted organ and tissue status	0.003	0.997
T79-T79 Certain early complications of trauma	0.003	0.997
T20-T25 Burns and corrosions of external body surface, specified by site	0.003	0.997
M13.98 Arthritis, unspecified (Other)	0.003	0.997
M13.91 Arthritis, unspecified (Shoulder region)	0.003	0.997
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.003	0.997
M25.47 Effusion of joint (Ankle and foot)	0.003	0.997
M06.8 Other specified rheumatoid arthritis	0.003	0.997
M06.4 Inflammatory polyarthropathy	0.003	0.997
M06.3 Rheumatoid nodule	0.003	0.997
M06.2 Rheumatoid bursitis	0.003	0.997
M06.1 Adult-onset Still's disease	0.003	0.997
M07.6 Other enteropathic arthropathies	0.003	0.997
M07.5 Arthropathy in ulcerative colitis	0.003	0.997
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.003	0.997
M07.2 Psoriatic spondylitis	0.003	0.997
M07.1 Arthritis mutilans	0.003	0.997
M07.0 Distal interphalangeal psoriatic arthropathy	0.003	0.997
M51.9 Intervertebral disk disorder, unspecified	0.003	0.997
M51.8 Other specified intervertebral disk disorders	0.003	0.997
M51.4 Schmorl's nodes	0.003	0.997
Z85.3 Personal history of malignant neoplasm of breast	0.003	0.997
Z42 Follow-up care involving plastic surgery	0.003	0.997
Z83 Family history of other specific disorders	0.003	0.997
S70-S79 Injuries to the hip and thigh	0.003	0.997
M13.93 Arthritis, unspecified (Forearm)	0.003	0.997
M25.49 Effusion of joint (Site unspecified)	0.003	0.997
M25.48 Effusion of joint (Other)	0.003	0.997
M25.45 Effusion of joint (Pelvic region and thigh)	0.003	0.997
M25.44 Effusion of joint (Hand)	0.003	0.997
M25.43 Effusion of joint (Forearm)	0.003	0.997
M25.42 Effusion of joint (Upper arm)	0.003	0.997
M25.41 Effusion of joint (Shoulder region)	0.003	0.997
M25.40 Effusion of joint (Multiple sites)	0.003	0.997
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.003	0.997
M65.8 Other synovitis and tenosynovitis	0.003	0.997
M65.4 Radial styloid tenosynovitis [de Quervain]	0.003	0.997
M65.2 Calcific tendinitis	0.003	0.997
M65.1 Other infective (teno)synovitis	0.003	0.997
M65.0 Abscess of tendon sheath	0.003	0.997
Z52 Donors of organs and tissues	0.003	0.997
Z49 Care involving dialysis	0.003	0.997
Z47 Other orthopaedic follow-up care	0.003	0.997
Z00-Z13 Persons encountering health services for examination and investigation	0.003	0.997
M13.92 Arthritis, unspecified (Upper arm)	0.003	0.997
Z54 Convalescence	0.003	0.997
Z44 Fitting and adjustment of external prosthetic device	0.003	0.997
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.003	0.997
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.003	0.997
M25.88 Other specified joint disorders (Other)	0.003	0.997
M25.87 Other specified joint disorders (Ankle and foot)	0.003	0.997
M25.86 Other specified joint disorders (Lower leg)	0.003	0.997
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.003	0.997
M25.84 Other specified joint disorders (Hand)	0.003	0.997
M25.83 Other specified joint disorders (Forearm)	0.003	0.997
M25.81 Other specified joint disorders (Shoulder region)	0.003	0.997
M07.3 Other psoriatic arthropathies	0.003	0.997
M54.5 Low back pain	0.003	0.997

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations