TreeWAS – Variant ID: rs1370053

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	0.000	0.994	0.006
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.994	0.006
I25.1 Atherosclerotic heart disease	0.000	0.994	0.006
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.995	0.005
I20-I25 Ischaemic heart diseases	0.000	0.995	0.005
I25.3 Aneurysm of heart	0.000	0.995	0.005
I25.5 Ischaemic cardiomyopathy	0.000	0.995	0.005
I25.2 Old myocardial infarction	0.000	0.995	0.005
I25.6 Silent myocardial ischaemia	0.000	0.995	0.004
I25.4 Coronary artery aneurysm	0.000	0.995	0.004
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.995	0.004
I21 Acute myocardial infarction	0.000	0.996	0.004
I20 Angina pectoris	0.000	0.996	0.004
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.996	0.004
I23 Certain current complications following acute myocardial infarction	0.000	0.996	0.004
I22 Subsequent myocardial infarction	0.000	0.996	0.004
I24 Other acute ischaemic heart diseases	0.000	0.996	0.004
Chapter IX Diseases of the circulatory system	0.000	0.996	0.004
I20.9 Angina pectoris, unspecified	0.000	0.996	0.004
I20.8 Other forms of angina pectoris	0.000	0.996	0.003
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.996	0.003
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.997	0.003
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.997	0.003
I21.4 Acute subendocardial myocardial infarction	0.000	0.997	0.003
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.997	0.003
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.997	0.003
I20.1 Angina pectoris with documented spasm	0.000	0.997	0.003
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.997	0.003
I20.0 Unstable angina	0.000	0.997	0.003
I21.9 Acute myocardial infarction, unspecified	0.000	0.997	0.003
I22.8 Subsequent myocardial infarction of other sites	0.000	0.997	0.003
I30-I52 Other forms of heart disease	0.000	0.997	0.003
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.997	0.003
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.997	0.003
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.997	0.003
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.997	0.003
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.997	0.003
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.997	0.003
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.997	0.003
I23.8 Other current complications following acute myocardial infarction	0.000	0.997	0.003
I05-I09 Chronic rheumatic heart diseases	0.000	0.997	0.003
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.997	0.003
I73 Other peripheral vascular diseases	0.000	0.997	0.003
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.997	0.003
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.997	0.003
I60-I69 Cerebrovascular diseases	0.000	0.997	0.003
I24.1 Dressler's syndrome	0.000	0.997	0.003
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.997	0.003
I74 Arterial embolism and thrombosis	0.000	0.997	0.003
I72 Other aneurysm	0.000	0.997	0.003
I00-I02 Acute rheumatic fever	0.000	0.997	0.003
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.997	0.003
I71 Aortic aneurysm and dissection	0.000	0.997	0.003
I24.8 Other forms of acute ischaemic heart disease	0.000	0.997	0.003
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.997	0.003
I78 Diseases of capillaries	0.000	0.997	0.003
I70 Atherosclerosis	0.000	0.997	0.003
I26 Pulmonary embolism	0.000	0.997	0.003
I50 Heart failure	0.000	0.997	0.003
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.997	0.003
I77 Other disorders of arteries and arterioles	0.000	0.997	0.003
I73.9 Peripheral vascular disease, unspecified	0.000	0.997	0.003
I27 Other pulmonary heart diseases	0.000	0.997	0.003
I33 Acute and subacute endocarditis	0.000	0.997	0.003
I50.1 Left ventricular failure	0.000	0.997	0.003
I28 Other diseases of pulmonary vessels	0.000	0.997	0.002
I46 Cardiac arrest	0.000	0.997	0.002
I63 Cerebral infarction	0.000	0.997	0.002
I38 Endocarditis, valve unspecified	0.000	0.997	0.002
I45 Other conduction disorders	0.000	0.997	0.002
I10-I15 Hypertensive diseases	0.000	0.997	0.003
I05 Rheumatic mitral valve diseases	0.000	0.997	0.002
I36 Nonrheumatic tricuspid valve disorders	0.000	0.997	0.002
I06 Rheumatic aortic valve diseases	0.000	0.997	0.002
I44 Atrioventricular and left bundle-branch block	0.000	0.997	0.002
I52 Other heart disorders in diseases classified elsewhere	0.000	0.997	0.002
I48 Atrial fibrillation and flutter	0.000	0.997	0.002
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.997	0.002
I41 Myocarditis in diseases classified elsewhere	0.000	0.997	0.002
I40 Acute myocarditis	0.000	0.997	0.002
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.997	0.002
I32 Pericarditis in diseases classified elsewhere	0.000	0.997	0.002
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.000	0.997	0.002
I07 Rheumatic tricuspid valve diseases	0.000	0.997	0.002
I37 Pulmonary valve disorders	0.000	0.997	0.002
I08 Multiple valve diseases	0.000	0.998	0.002
I35 Nonrheumatic aortic valve disorders	0.000	0.998	0.002
I30 Acute pericarditis	0.000	0.998	0.002
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.998	0.002
I09 Other rheumatic heart diseases	0.000	0.998	0.002
I62 Other nontraumatic intracranial haemorrhage	0.000	0.998	0.002
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.998	0.002
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.998	0.002
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.998	0.002
I72.9 Aneurysm of unspecified site	0.000	0.998	0.002
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.998	0.002
I73.8 Other specified peripheral vascular diseases	0.000	0.998	0.002
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.998	0.002
I49 Other cardiac arrhythmias	0.000	0.998	0.002
I34 Nonrheumatic mitral valve disorders	0.000	0.998	0.002
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.998	0.002
I72.3 Aneurysm of iliac artery	0.000	0.998	0.002
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.998	0.002
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.998	0.002
I42 Cardiomyopathy	0.000	0.998	0.002
I31 Other diseases of pericardium	0.000	0.998	0.002
I74.5 Embolism and thrombosis of iliac artery	0.000	0.998	0.002
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.998	0.002
I33.0 Acute and subacute infective endocarditis	0.000	0.998	0.002
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.998	0.002
I73.0 Raynaud's syndrome	0.000	0.998	0.002
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.998	0.002
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.998	0.002
I02 Rheumatic chorea	0.000	0.998	0.002
I01 Rheumatic fever with heart involvement	0.000	0.998	0.002
I00 Rheumatic fever without mention of heart involvement	0.000	0.998	0.002
I51 Complications and ill-defined descriptions of heart disease	0.000	0.998	0.002
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.998	0.002
I60 Subarachnoid haemorrhage	0.000	0.998	0.002
I50.9 Heart failure, unspecified	0.000	0.998	0.002
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.998	0.002
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.998	0.002
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.998	0.002
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.998	0.002
I72.2 Aneurysm of renal artery	0.000	0.998	0.002
I72.1 Aneurysm of artery of upper extremity	0.000	0.998	0.002
I72.0 Aneurysm of carotid artery	0.000	0.998	0.002
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.998	0.002
I74.8 Embolism and thrombosis of other arteries	0.000	0.998	0.002
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.998	0.002
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.998	0.002
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.998	0.002
I78.8 Other diseases of capillaries	0.000	0.998	0.002
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.998	0.002
I47 Paroxysmal tachycardia	0.000	0.998	0.002
I99 Other and unspecified disorders of circulatory system	0.000	0.998	0.002
I63.9 Cerebral infarction, unspecified	0.000	0.998	0.002
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.998	0.002
I72.8 Aneurysm of other specified arteries	0.000	0.998	0.002
I72.4 Aneurysm of artery of lower extremity	0.000	0.998	0.002
I46.9 Cardiac arrest, unspecified	0.000	0.998	0.002
I71.0 Dissection of aorta [any part]	0.000	0.998	0.002
I27.0 Primary pulmonary hypertension	0.000	0.998	0.002
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.998	0.002
I69 Sequelae of cerebrovascular disease	0.000	0.998	0.002
I27.9 Pulmonary heart disease, unspecified	0.000	0.998	0.002
I70.9 Generalised and unspecified atherosclerosis	0.000	0.998	0.002
I70.8 Atherosclerosis of other arteries	0.000	0.998	0.002
I70.1 Atherosclerosis of renal artery	0.000	0.998	0.002
I70.0 Atherosclerosis of aorta	0.000	0.998	0.002
I78.9 Disease of capillaries, unspecified	0.000	0.998	0.002
I67 Other cerebrovascular diseases	0.000	0.998	0.002
I95 Hypotension	0.000	0.998	0.002
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.998	0.002
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.998	0.002
I61 Intracerebral haemorrhage	0.000	0.998	0.002
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.998	0.002
I77.1 Stricture of artery	0.000	0.998	0.002
I27.2 Other secondary pulmonary hypertension	0.000	0.998	0.002
I28.8 Other specified diseases of pulmonary vessels	0.000	0.998	0.002
I77.5 Necrosis of artery	0.000	0.998	0.002
I77.4 Coeliac artery compression syndrome	0.000	0.998	0.002
I77.3 Arterial fibromuscular dysplasia	0.000	0.998	0.002
I77.2 Rupture of artery	0.000	0.998	0.002
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.998	0.002
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.998	0.002
I79.1 Aortitis in diseases classified elsewhere	0.000	0.998	0.002
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.998	0.002
I27.8 Other specified pulmonary heart diseases	0.000	0.998	0.002
I27.1 Kyphoscoliotic heart disease	0.000	0.998	0.002
I45.1 Other and unspecified right bundle-branch block	0.000	0.998	0.002
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.998	0.002
I77.8 Other specified disorders of arteries and arterioles	0.000	0.998	0.002
I77.0 Arteriovenous fistula, acquired	0.000	0.998	0.002
I77.6 Arteritis, unspecified	0.000	0.998	0.002
I11 Hypertensive heart disease	0.000	0.998	0.002
I33.9 Acute endocarditis, unspecified	0.000	0.998	0.002
I78.1 Naevus, nonneoplastic	0.000	0.998	0.002
I12 Hypertensive renal disease	0.000	0.998	0.002
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.998	0.002
I28.1 Aneurysm of pulmonary artery	0.000	0.998	0.002
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.998	0.002
I45.3 Trifascicular block	0.000	0.998	0.002
I63.8 Other cerebral infarction	0.000	0.998	0.002
I46.1 Sudden cardiac death, so described	0.000	0.998	0.002
I05.2 Mitral stenosis with insufficiency	0.000	0.998	0.002
I05.1 Rheumatic mitral insufficiency	0.000	0.998	0.002
I06.1 Rheumatic aortic insufficiency	0.000	0.998	0.002
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.998	0.002
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.998	0.002
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.998	0.002
I44.4 Left anterior fascicular block	0.000	0.998	0.002
I44.1 Atrioventricular block, second degree	0.000	0.998	0.002
I46.0 Cardiac arrest with successful resuscitation	0.000	0.998	0.002
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.998	0.002
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.998	0.002
I45.4 Nonspecific intraventricular block	0.000	0.998	0.002
I45.0 Right fascicular block	0.000	0.998	0.002
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.998	0.002
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.998	0.002
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.998	0.002
I13 Hypertensive heart and renal disease	0.000	0.998	0.002
I05.8 Other mitral valve diseases	0.000	0.998	0.002
I08.8 Other multiple valve diseases	0.000	0.998	0.002
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.998	0.002
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.998	0.002
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.998	0.002
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.998	0.002
I45.8 Other specified conduction disorders	0.000	0.998	0.002
I45.5 Other specified heart block	0.000	0.998	0.002
I45.2 Bifascicular block	0.000	0.998	0.002
I15 Secondary hypertension	0.000	0.998	0.002
I05.0 Mitral stenosis	0.000	0.998	0.002
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.998	0.002
I06.8 Other rheumatic aortic valve diseases	0.000	0.998	0.002
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.998	0.002
I06.0 Rheumatic aortic stenosis	0.000	0.998	0.002
I07.1 Tricuspid insufficiency	0.000	0.998	0.002
I45.9 Conduction disorder, unspecified	0.000	0.998	0.002
I45.6 Preexcitation syndrome	0.000	0.998	0.002
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.998	0.002
I86 Varicose veins of other sites	0.000	0.998	0.002
I05.9 Mitral valve disease, unspecified	0.000	0.998	0.002
I31.0 Chronic adhesive pericarditis	0.000	0.998	0.002
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.998	0.002
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.998	0.002
I35.1 Aortic (valve) insufficiency	0.000	0.998	0.002
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.998	0.002
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.998	0.002
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.998	0.002
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.998	0.002
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.998	0.002
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.998	0.002
I40.8 Other acute myocarditis	0.000	0.998	0.002
I40.1 Isolated myocarditis	0.000	0.998	0.002
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.998	0.002
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.998	0.002
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.998	0.002
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.998	0.002
I44.5 Left posterior fascicular block	0.000	0.998	0.002
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.998	0.002
I48.4 Atypical atrial flutter	0.000	0.998	0.002
I48.3 Typical atrial flutter	0.000	0.998	0.002
I48.2 Chronic atrial fibrillation	0.000	0.998	0.002
I48.1 Persistent atrial fibrillation	0.000	0.998	0.002
I48.0 Paroxysmal atrial fibrillation	0.000	0.998	0.002
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.998	0.002
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.998	0.002
I65.2 Occlusion and stenosis of carotid artery	0.000	0.998	0.002
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.998	0.002
I07.9 Tricuspid valve disease, unspecified	0.000	0.998	0.002
I07.8 Other tricuspid valve diseases	0.000	0.998	0.002
I07.2 Tricuspid stenosis with insufficiency	0.000	0.998	0.002
I07.0 Tricuspid stenosis	0.000	0.998	0.002
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.998	0.002
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.998	0.002
I37.9 Pulmonary valve disorder, unspecified	0.000	0.998	0.002
I37.8 Other pulmonary valve disorders	0.000	0.998	0.002
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.998	0.002
I37.0 Pulmonary valve stenosis	0.000	0.998	0.002
I40.9 Acute myocarditis, unspecified	0.000	0.998	0.002
I40.0 Infective myocarditis	0.000	0.998	0.002
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.998	0.002
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.998	0.002
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
I44.6 Other and unspecified fascicular block	0.000	0.998	0.002
I44.3 Other and unspecified atrioventricular block	0.000	0.998	0.002
I44.2 Atrioventricular block, complete	0.000	0.998	0.002
I44.0 Atrioventricular block, first degree	0.000	0.998	0.002
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.998	0.002
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.998	0.002
I08.9 Multiple valve disease, unspecified	0.000	0.998	0.002
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.998	0.002
I08.0 Disorders of both mitral and aortic valves	0.000	0.998	0.002
I09.9 Rheumatic heart disease, unspecified	0.000	0.998	0.002
I09.8 Other specified rheumatic heart diseases	0.000	0.998	0.002
I09.2 Chronic rheumatic pericarditis	0.000	0.998	0.002
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.998	0.002
I09.0 Rheumatic myocarditis	0.000	0.998	0.002
I30.8 Other forms of acute pericarditis	0.000	0.998	0.002
I30.1 Infective pericarditis	0.000	0.998	0.002
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.998	0.002
I37.1 Pulmonary valve insufficiency	0.000	0.998	0.002
I42.0 Dilated cardiomyopathy	0.000	0.998	0.002
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.998	0.002
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
I98.0 Cardiovascular syphilis	0.000	0.998	0.002
I87 Other disorders of veins	0.000	0.998	0.002
I82 Other venous embolism and thrombosis	0.000	0.998	0.002
I30.9 Acute pericarditis, unspecified	0.000	0.998	0.002
I34.0 Mitral (valve) insufficiency	0.000	0.998	0.002
I35.9 Aortic valve disorder, unspecified	0.000	0.998	0.002
I35.8 Other aortic valve disorders	0.000	0.998	0.002
I49.8 Other specified cardiac arrhythmias	0.000	0.998	0.002
I49.0 Ventricular fibrillation and flutter	0.000	0.998	0.002
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.998	0.002
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.998	0.002
I62.1 Nontraumatic extradural haemorrhage	0.000	0.998	0.002
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.998	0.002
I88 Nonspecific lymphadenitis	0.000	0.998	0.002
I85 Oesophageal varices	0.000	0.998	0.002
I81 Portal vein thrombosis	0.000	0.998	0.002
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.998	0.002
I31.8 Other specified diseases of pericardium	0.000	0.998	0.002
I31.2 Haemopericardium, not elsewhere classified	0.000	0.998	0.002
I31.1 Chronic constrictive pericarditis	0.000	0.998	0.002
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.998	0.002
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.998	0.002
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.998	0.002
I42.5 Other restrictive cardiomyopathy	0.000	0.998	0.002
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.998	0.002
I44.7 Left bundle-branch block, unspecified	0.000	0.998	0.002
I49.9 Cardiac arrhythmia, unspecified	0.000	0.998	0.002
I49.3 Ventricular premature depolarisation	0.000	0.998	0.002
I49.2 Junctional premature depolarisation	0.000	0.998	0.002
I50.0 Congestive heart failure	0.000	0.998	0.002
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.998	0.002
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.998	0.002
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.998	0.002
I65.1 Occlusion and stenosis of basilar artery	0.000	0.998	0.002
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.998	0.002
I35.0 Aortic (valve) stenosis	0.000	0.998	0.002
I42.8 Other cardiomyopathies	0.000	0.998	0.002
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.998	0.002
I42.6 Alcoholic cardiomyopathy	0.000	0.998	0.002
I42.4 Endocardial fibroelastosis	0.000	0.998	0.002
I49.1 Atrial premature depolarisation	0.000	0.998	0.002
I51.8 Other ill-defined heart diseases	0.000	0.998	0.002
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.998	0.002
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.998	0.002
I97.0 Postcardiotomy syndrome	0.000	0.998	0.002
D25.9 Leiomyoma of uterus, unspecified	0.002	0.998	0.000
I42.2 Other hypertrophic cardiomyopathy	0.000	0.998	0.002
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.998	0.002
I49.4 Other and unspecified premature depolarisation	0.000	0.998	0.002
I51.5 Myocardial degeneration	0.000	0.998	0.002
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.998	0.002
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.998	0.002
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.998	0.002
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
I68.0 Cerebral amyloid angiopathy	0.000	0.998	0.002
I97.1 Other functional disturbances following cardiac surgery	0.000	0.998	0.002
D25 Leiomyoma of uterus	0.002	0.998	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.998	0.002
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.998	0.002
I01.8 Other acute rheumatic heart disease	0.000	0.998	0.002
I01.2 Acute rheumatic myocarditis	0.000	0.998	0.002
I01.1 Acute rheumatic endocarditis	0.000	0.998	0.002
I01.0 Acute rheumatic pericarditis	0.000	0.998	0.002
I02.9 Rheumatic chorea without heart involvement	0.000	0.998	0.002
I02.0 Rheumatic chorea with heart involvement	0.000	0.998	0.002
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.998	0.002
I47.2 Ventricular tachycardia	0.000	0.998	0.002
I49.5 Sick sinus syndrome	0.000	0.998	0.002
I51.9 Heart disease, unspecified	0.000	0.998	0.002
I51.6 Cardiovascular disease, unspecified	0.000	0.998	0.002
I51.4 Myocarditis, unspecified	0.000	0.998	0.002
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.998	0.002
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.998	0.002
I51.0 Cardiac septal defect, acquired	0.000	0.998	0.002
I60.8 Other subarachnoid haemorrhage	0.000	0.998	0.002
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.998	0.002
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.998	0.002
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.998	0.002
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.998	0.002
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.998	0.002
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.998	0.002
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.998	0.002
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.998	0.002
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.998	0.002
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.998	0.002
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.998	0.002
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.998	0.002
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.998	0.002
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.998	0.002
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.998	0.002
I83 Varicose veins of lower extremities	0.000	0.998	0.002
I31.9 Disease of pericardium, unspecified	0.000	0.998	0.002
I34.1 Mitral (valve) prolapse	0.000	0.998	0.002
I42.9 Cardiomyopathy, unspecified	0.000	0.998	0.002
I47.0 Reentry ventricular arrhythmia	0.000	0.998	0.002
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.998	0.002
D10-D36 Benign neoplasms	0.002	0.998	0.000
I12.9 Hypertensive renal disease without renal failure	0.000	0.998	0.002
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.998	0.002
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.998	0.002
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.998	0.002
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.998	0.002
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.998	0.002
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.998	0.002
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.998	0.002
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.998	0.002
I31.3 Pericardial effusion (noninflammatory)	0.000	0.998	0.002
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.998	0.002
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.998	0.002
I67.5 Moyamoya disease	0.000	0.998	0.002
I67.4 Hypertensive encephalopathy	0.000	0.998	0.002
I67.3 Progressive vascular leukoencephalopathy	0.000	0.998	0.002
I67.1 Cerebral aneurysm, nonruptured	0.000	0.998	0.002
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.998	0.002
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.998	0.002
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.998	0.002
D17 Benign lipomatous neoplasm	0.002	0.998	0.000
I80 Phlebitis and thrombophlebitis	0.000	0.998	0.002
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.998	0.002
I61.8 Other intracerebral haemorrhage	0.000	0.998	0.002
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.998	0.002
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.998	0.002
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.998	0.002
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.998	0.002
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.998	0.002
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.998	0.002
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.998	0.002
I67.8 Other specified cerebrovascular diseases	0.000	0.998	0.002
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.998	0.002
I95.8 Other hypotension	0.000	0.998	0.002
I95.1 Orthostatic hypotension	0.000	0.998	0.002
I95.0 Idiopathic hypotension	0.000	0.998	0.002
I67.2 Cerebral atherosclerosis	0.000	0.998	0.002
I69.3 Sequelae of cerebral infarction	0.000	0.998	0.002
I95.2 Hypotension due to drugs	0.000	0.998	0.002
D22 Melanocytic naevi	0.002	0.998	0.000
I51.7 Cardiomegaly	0.000	0.998	0.002
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.998	0.002
L03.1 Cellulitis of other parts of limb	0.000	0.998	0.002
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.998	0.002
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.998	0.002
I67.9 Cerebrovascular disease, unspecified	0.000	0.998	0.002
I95.9 Hypotension, unspecified	0.000	0.998	0.002
C61 Malignant neoplasm of prostate	0.000	0.998	0.002
D23 Other benign neoplasms of skin	0.002	0.998	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.998	0.002
L72.1 Trichilemmal cyst	0.000	0.998	0.002
I47.1 Supraventricular tachycardia	0.000	0.998	0.001
I86.4 Gastric varices	0.000	0.998	0.002
D25.1 Intramural leiomyoma of uterus	0.002	0.998	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.998	0.002
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.998	0.002
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.998	0.002
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.998	0.002
I86.1 Scrotal varices	0.000	0.998	0.002
I15.9 Seconday hypertension, unspecified	0.000	0.998	0.002
I15.8 Other secondary hypertension	0.000	0.998	0.002
I15.2 Hypertension secondary to endocrine disorders	0.000	0.998	0.002
I15.0 Renovascular hypertension	0.000	0.998	0.002
I86.3 Vulval varices	0.000	0.998	0.002
I86.0 Sublingual varices	0.000	0.998	0.002
D24 Benign neoplasm of breast	0.002	0.998	0.000
I84 Haemorrhoids	0.000	0.998	0.002
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.002	0.998	0.000
I15.1 Hypertension secondary to other renal disorders	0.000	0.998	0.002
I82.8 Embolism and thrombosis of other specified veins	0.000	0.998	0.002
I86.8 Varicose veins of other specified sites	0.000	0.998	0.002
I86.2 Pelvic varices	0.000	0.998	0.002
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.998	0.002
I89.1 Lymphangitis	0.000	0.998	0.002
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.002	0.998	0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.002	0.998	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.998	0.001
I82.3 Embolism and thrombosis of renal vein	0.000	0.998	0.001
I82.2 Embolism and thrombosis of vena cava	0.000	0.998	0.001
I82.1 Thrombophlebitis migrans	0.000	0.998	0.001
I82.0 Budd-Chiari syndrome	0.000	0.998	0.001
I85.9 Oesophageal varices without bleeding	0.000	0.998	0.001
I87.9 Disorder of vein, unspecified	0.000	0.998	0.001
I87.0 Postphlebitic syndrome	0.000	0.998	0.001
I88.8 Other nonspecific lymphadenitis	0.000	0.998	0.001
I88.1 Chronic lymphadenitis, except mesenteric	0.000	0.998	0.001
I88.0 Nonspecific mesenteric lymphadenitis	0.000	0.998	0.001
D36 Benign neoplasm of other and unspecified sites	0.002	0.998	0.000
I85.0 Oesophageal varices with bleeding	0.000	0.998	0.001
I87.8 Other specified disorders of veins	0.000	0.998	0.001
I87.1 Compression of vein	0.000	0.998	0.001
I88.9 Nonspecific lymphadenitis, unspecified	0.000	0.998	0.001
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.000	0.998	0.001
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.998	0.001
D21 Other benign neoplasms of connective and other soft tissue	0.002	0.998	0.000
D27 Benign neoplasm of ovary	0.002	0.998	0.000
D25.2 Subserosal leiomyoma of uterus	0.002	0.998	0.000
L40.9 Psoriasis, unspecified	0.000	0.998	0.002
D33 Benign neoplasm of brain and other parts of central nervous system	0.002	0.998	0.000
D26 Other benign neoplasms of uterus	0.002	0.998	0.000
D16 Benign neoplasm of bone and articular cartilage	0.002	0.998	0.000
D11 Benign neoplasm of major salivary glands	0.002	0.998	0.000
L72 Follicular cysts of skin and subcutaneous tissue	0.000	0.998	0.002
D22.3 Melanocytic naevi of other and unspecified parts of face	0.002	0.998	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.998	0.001
D31 Benign neoplasm of eye and adnexa	0.001	0.998	0.000
D30 Benign neoplasm of urinary organs	0.001	0.998	0.000
D29 Benign neoplasm of male genital organs	0.001	0.998	0.000
D28 Benign neoplasm of other and unspecified female genital organs	0.001	0.998	0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.001	0.998	0.000
D17.9 Benign lipomatous neoplasm, unspecified	0.001	0.998	0.000
D17.7 Benign lipomatous neoplasm of other sites	0.001	0.998	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.001	0.998	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.998	0.001
I89.0 Lymphoedema, not elsewhere classified	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations