TreeWAS – Variant ID: rs138642423

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter XV Pregnancy, childbirth and the puerperium	1.000	0.000	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.998	0.002	0.000
O60-O75 Complications of labour and delivery	0.996	0.004	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.993	0.007	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.980	0.020	0.000
# Top node	0.977	0.023	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.971	0.029	0.000
S80-S89 Injuries to the knee and lower leg	0.969	0.031	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.966	0.034	0.000
O26.8 Other specified pregnancy-related conditions	0.957	0.043	0.000
O32.1 Maternal care for breech presentation	0.943	0.057	0.000
O36 Maternal care for other known or suspected foetal problems	0.942	0.058	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.939	0.061	0.000
O63 Long labour	0.938	0.062	0.000
S82 Fracture of lower leg, including ankle	0.929	0.071	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.921	0.079	0.000
S20-S29 Injuries to the thorax	0.909	0.091	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.898	0.102	0.000
S82.8 Fractures of other parts of lower leg	0.893	0.107	0.000
Chapter XX External causes of morbidity and mortality	0.891	0.109	0.000
O20 Haemorrhage in early pregnancy	0.886	0.114	0.000
O63.1 Prolonged second stage (of labour)	0.877	0.123	0.000
O36.8 Maternal care for other specified foetal problems	0.875	0.125	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.872	0.128	0.000
O80-O84 Delivery	0.861	0.139	0.000
O70 Perineal laceration during delivery	0.858	0.142	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.855	0.145	0.000
O47 False labour	0.854	0.146	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.853	0.147	0.000
S80 Superficial injury of lower leg	0.848	0.152	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.846	0.154	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.843	0.157	0.000
S81 Open wound of lower leg	0.843	0.157	0.000
M80-M85 Disorders of bone density and structure	0.839	0.161	0.000
S60-S69 Injuries to the wrist and hand	0.830	0.170	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.826	0.174	0.000
Chapter VI Diseases of the nervous system	0.824	0.176	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.821	0.179	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.820	0.180	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.817	0.183	0.000
O20.0 Threatened abortion	0.802	0.198	0.000
O28 Abnormal findings on antenatal screening of mother	0.797	0.203	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.792	0.208	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.790	0.210	0.000
O36.9 Maternal care for foetal problem, unspecified	0.784	0.216	0.000
O66 Other obstructed labour	0.783	0.217	0.000
M45-M49 Spondylopathies	0.774	0.226	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.773	0.227	0.000
T79-T79 Certain early complications of trauma	0.770	0.229	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.770	0.230	0.000
M86-M90 Other osteopathies	0.766	0.234	0.000
O73 Retained placenta and membranes, without haemorrhage	0.766	0.234	0.000
S00-S09 Injuries to the head	0.764	0.236	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.764	0.236	0.000
S80.9 Superficial injury of lower leg, unspecified	0.762	0.238	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.762	0.238	0.000
Chapter XXII Codes for special purposes	0.759	0.241	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.757	0.243	0.000
S20 Superficial injury of thorax	0.756	0.244	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.755	0.245	0.000
S81.0 Open wound of knee	0.755	0.245	0.000
O48 Prolonged pregnancy	0.754	0.246	0.000
M81 Osteoporosis without pathological fracture	0.751	0.249	0.000
S50-S59 Injuries to the elbow and forearm	0.749	0.251	0.000
O24 Diabetes mellitus in pregnancy	0.748	0.252	0.000
Y43 Primarily systemic agents	0.746	0.254	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.740	0.259	0.002
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.741	0.259	0.000
V20-V29 Motorcycle rider injured in transport accident	0.740	0.260	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.737	0.263	0.000
O70.1 Second degree perineal laceration during delivery	0.733	0.267	0.000
O72 Postpartum haemorrhage	0.732	0.268	0.000
O82 Single delivery by Caesarean section	0.730	0.270	0.000
S82.81 Fractures of other parts of lower leg (open)	0.729	0.271	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.729	0.271	0.000
O63.9 Long labour, unspecified	0.727	0.273	0.000
Q60-Q64 Congenital malformations of the urinary system	0.727	0.273	0.000
S10-S19 Injuries to the neck	0.726	0.273	0.000
Chapter I Certain infectious and parasitic diseases	0.726	0.274	0.000
M15-M19 Arthrosis	0.725	0.275	0.000
S82.2 Fracture of shaft of tibia	0.724	0.276	0.000
S27 Injury of other and unspecified intrathoracic organs	0.724	0.276	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.721	0.278	0.001
S82.0 Fracture of patella	0.721	0.279	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.718	0.282	0.000
O85-O92 Complications predominantly related to the puerperium	0.717	0.283	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.716	0.284	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.716	0.284	0.000
O45 Premature separation of placenta [abruptio placentae]	0.715	0.285	0.000
O44 Placenta praevia	0.715	0.285	0.000
O43 Placental disorders	0.715	0.285	0.000
O41 Other disorders of amniotic fluid and membranes	0.715	0.285	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.715	0.285	0.000
O33 Maternal care for known or suspected disproportion	0.715	0.285	0.000
O31 Complications specific to multiple gestation	0.715	0.285	0.000
O40 Polyhydramnios	0.715	0.285	0.000
O74 Complications of anaesthesia during labour and delivery	0.714	0.286	0.000
O71 Other obstetric trauma	0.714	0.286	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.714	0.286	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.714	0.286	0.000
O62 Abnormalities of forces of labour	0.714	0.286	0.000
O61 Failed induction of labour	0.714	0.286	0.000
O60 Preterm delivery	0.714	0.286	0.000
O29 Complications of anaesthesia during pregnancy	0.712	0.288	0.000
O23 Infections of genito-urinary tract in pregnancy	0.712	0.288	0.000
O22 Venous complications in pregnancy	0.712	0.288	0.000
O21 Excessive vomiting in pregnancy	0.712	0.288	0.000
O25 Malnutrition in pregnancy	0.712	0.288	0.000
O63.0 Prolonged first stage (of labour)	0.711	0.289	0.000
S61 Open wound of wrist and hand	0.710	0.290	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.706	0.294	0.000
W00-W19 Falls	0.705	0.295	0.000
S40-S49 Injuries to the shoulder and upper arm	0.704	0.296	0.000
S70-S79 Injuries to the hip and thigh	0.703	0.297	0.000
T33-T35 Frostbite	0.703	0.297	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.703	0.297	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.703	0.297	0.000
T00-T07 Injuries involving multiple body regions	0.703	0.297	0.000
D70 Agranulocytosis	0.703	0.297	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.702	0.298	0.000
Chapter II Neoplasms	0.702	0.298	0.000
S82.6 Fracture of lateral malleolus	0.701	0.299	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.700	0.300	0.000
M91-M94 Chondropathies	0.699	0.301	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.696	0.304	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.696	0.304	0.000
O26.5 Maternal hypotension syndrome	0.696	0.304	0.000
O26.4 Herpes gestationis	0.696	0.304	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.696	0.304	0.000
O26.2 Pregnancy care of habitual aborter	0.696	0.304	0.000
O26.1 Low weight gain in pregnancy	0.696	0.304	0.000
O26.0 Excessive weight gain in pregnancy	0.696	0.304	0.000
Y43.3 Other antineoplastic drugs	0.695	0.305	0.000
S89 Other and unspecified injuries of lower leg	0.695	0.305	0.000
S88 Traumatic amputation of lower leg	0.695	0.305	0.000
S87 Crushing injury of lower leg	0.695	0.305	0.000
S86 Injury of muscle and tendon at lower leg level	0.695	0.305	0.000
S85 Injury of blood vessels at lower leg level	0.695	0.305	0.000
S84 Injury of nerves at lower leg level	0.695	0.305	0.000
S90-S99 Injuries to the ankle and foot	0.694	0.306	0.000
M47 Spondylosis	0.693	0.307	0.000
T66-T78 Other and unspecified effects of external causes	0.693	0.307	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.692	0.307	0.000
O32.8 Maternal care for other malpresentation of foetus	0.692	0.307	0.000
O32.6 Maternal care for compound presentation	0.692	0.307	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.692	0.307	0.000
O32.4 Maternal care for high head at term	0.692	0.307	0.000
O32.3 Maternal care for face, brow and chin presentation	0.692	0.307	0.000
O32.2 Maternal care for transverse and oblique lie	0.692	0.307	0.000
O32.0 Maternal care for unstable lie	0.692	0.307	0.000
M81.9 Osteoporosis, unspecified	0.688	0.312	0.000
M40-M43 Deforming dorsopathies	0.686	0.314	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.685	0.315	0.000
Chapter VIII Diseases of the ear and mastoid process	0.685	0.315	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.685	0.315	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.685	0.315	0.000
M50-M54 Other dorsopathies	0.684	0.316	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.684	0.316	0.000
X20-X29 Contact with venomous animals and plants	0.682	0.318	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.681	0.319	0.000
T93 Sequelae of injuries of lower limb	0.680	0.320	0.000
V80-V89 Other land transport accidents	0.679	0.321	0.000
S82.1 Fracture of upper end of tibia	0.678	0.322	0.000
O30 Multiple gestation	0.677	0.323	0.000
O26.9 Pregnancy-related condition, unspecified	0.677	0.323	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.676	0.324	0.000
O36.6 Maternal care for excessive foetal growth	0.676	0.324	0.000
O36.5 Maternal care for poor foetal growth	0.676	0.324	0.000
O36.4 Maternal care for intra-uterine death	0.676	0.324	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.676	0.324	0.000
O36.2 Maternal care for hydrops foetalis	0.676	0.324	0.000
O36.1 Maternal care for other isoimmunisation	0.676	0.324	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.676	0.324	0.000
O80 Single spontaneous delivery	0.675	0.325	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.673	0.327	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.673	0.327	0.000
M05-M14 Inflammatory polyarthropathies	0.671	0.329	0.000
O42 Premature rupture of membranes	0.668	0.332	0.000
O70.0 First degree perineal laceration during delivery	0.667	0.333	0.000
S82.9 Fracture of lower leg, part unspecified	0.666	0.334	0.000
S82.7 Multiple fractures of lower leg	0.666	0.334	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.666	0.334	0.000
S82.5 Fracture of medial malleolus	0.662	0.338	0.000
M84 Disorders of continuity of bone	0.661	0.339	0.000
M60-M63 Disorders of muscles	0.661	0.339	0.000
M00-M03 Infectious arthropathies	0.661	0.339	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.658	0.342	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.658	0.342	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.657	0.343	0.000
M17 Gonarthrosis [arthrosis of knee]	0.656	0.344	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.656	0.344	0.000
S29 Other and unspecified injuries of thorax	0.652	0.348	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.652	0.348	0.000
S26 Injury of heart	0.652	0.348	0.000
S25 Injury of blood vessels of thorax	0.652	0.348	0.000
S24 Injury of nerves and spinal cord at thorax level	0.652	0.348	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.652	0.348	0.000
S21 Open wound of thorax	0.652	0.348	0.000
S22.4 Multiple fractures of ribs	0.651	0.348	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.651	0.349	0.000
O00-O08 Pregnancy with abortive outcome	0.647	0.353	0.000
O16 Unspecified maternal hypertension	0.647	0.353	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.646	0.354	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.644	0.356	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.644	0.356	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.644	0.356	0.000
O34.6 Maternal care for abnormality of vagina	0.644	0.356	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.644	0.356	0.000
O34.4 Maternal care for other abnormalities of cervix	0.644	0.356	0.000
O34.3 Maternal care for cervical incompetence	0.644	0.356	0.000
O34.1 Maternal care for tumour of corpus uteri	0.644	0.356	0.000
O34.0 Maternal care for congenital malformation of uterus	0.644	0.356	0.000
S82.4 Fracture of fibula alone	0.642	0.357	0.000
S82.86 Maisonneuve's fracture	0.640	0.360	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.640	0.360	0.000
Y40 Systemic antibiotics	0.639	0.361	0.000
S67 Crushing injury of wrist and hand	0.639	0.361	0.000
W20-W49 Exposure to inanimate mechanical forces	0.639	0.361	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.639	0.361	0.000
Y35-Y36 Legal intervention and operations of war	0.639	0.361	0.000
Y10-Y34 Event of undetermined intent	0.639	0.361	0.000
Y00-Y09 Assault	0.639	0.361	0.000
X85-X99 Assault	0.639	0.361	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.639	0.361	0.000
X50-X57 Overexertion, travel and privation	0.639	0.361	0.000
X30-X39 Exposure to forces of nature	0.639	0.361	0.000
X10-X19 Contact with heat and hot substances	0.639	0.361	0.000
X00-X09 Exposure to smoke, fire and flames	0.639	0.361	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.639	0.361	0.000
W75-W84 Other accidental threats to breathing	0.639	0.361	0.000
W65-W74 Accidental drowning and submersion	0.639	0.361	0.000
W50-W64 Exposure to animate mechanical forces	0.639	0.361	0.000
V98-V99 Other and unspecified transport accidents	0.639	0.361	0.000
V95-V97 Air and space transport accidents	0.639	0.361	0.000
V90-V94 Water transport accidents	0.639	0.361	0.000
V70-V79 Bus occupant injured in transport accident	0.639	0.361	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.639	0.361	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.639	0.361	0.000
V40-V49 Car occupant injured in transport accident	0.639	0.361	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.639	0.361	0.000
V01-V09 Pedestrian injured in transport accident	0.639	0.361	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.639	0.361	0.000
M17.9 Gonarthrosis, unspecified	0.637	0.363	0.000
M47.9 Spondylosis, unspecified	0.637	0.363	0.000
M65-M68 Disorders of synovium and tendon	0.637	0.363	0.000
T91 Sequelae of injuries of neck and trunk	0.636	0.364	0.000
O20.8 Other haemorrhage in early pregnancy	0.635	0.365	0.000
A30-A49 Other bacterial diseases	0.635	0.365	0.000
C51-C58 Malignant neoplasms of female genital organs	0.635	0.365	0.000
S60 Superficial injury of wrist and hand	0.635	0.365	0.000
Q63 Other congenital malformations of kidney	0.634	0.365	0.000
V10-V19 Pedal cyclist injured in transport accident	0.634	0.366	0.000
Q50-Q56 Congenital malformations of genital organs	0.633	0.367	0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.631	0.369	0.000
D80-D89 Certain disorders involving the immune mechanism	0.631	0.369	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.631	0.369	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.629	0.371	0.000
S22.3 Fracture of rib	0.628	0.371	0.000
O82.1 Delivery by emergency Caesarean section	0.628	0.372	0.000
G30-G32 Other degenerative diseases of the nervous system	0.628	0.372	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.627	0.373	0.000
M80 Osteoporosis with pathological fracture	0.627	0.373	0.000
D55-D59 Haemolytic anaemias	0.625	0.375	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.624	0.376	0.000
D73 Diseases of spleen	0.623	0.377	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.620	0.380	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.619	0.381	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.618	0.382	0.000
M46 Other inflammatory spondylopathies	0.617	0.383	0.000
O84 Multiple delivery	0.617	0.383	0.000
O83 Other assisted single delivery	0.617	0.383	0.000
O81 Single delivery by forceps and vacuum extractor	0.617	0.383	0.000
X60-X84 Intentional self-harm	0.616	0.384	0.000
Y44 Agents primarily affecting blood constituents	0.616	0.384	0.000
S81.9 Open wound of lower leg, part unspecified	0.616	0.384	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.616	0.384	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.615	0.384	0.000
O70.9 Perineal laceration during delivery, unspecified	0.615	0.385	0.000
O70.3 Fourth degree perineal laceration during delivery	0.615	0.385	0.000
O70.2 Third degree perineal laceration during delivery	0.615	0.385	0.000
O47.0 False labour before 37 completed weeks of gestation	0.614	0.386	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.614	0.386	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.613	0.387	0.000
Q80-Q89 Other congenital malformations	0.613	0.387	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.613	0.387	0.000
Q35-Q37 Cleft lip and cleft palate	0.613	0.387	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.613	0.387	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.613	0.387	0.000
Q00-Q07 Congenital malformations of the nervous system	0.613	0.387	0.000
T31 Burns classified according to extent of body surface involved	0.608	0.391	0.000
S80.8 Other superficial injuries of lower leg	0.608	0.392	0.000
S80.7 Multiple superficial injuries of lower leg	0.608	0.392	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.608	0.392	0.000
S80.0 Contusion of knee	0.608	0.392	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.608	0.392	0.000
S02 Fracture of skull and facial bones	0.607	0.392	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.606	0.393	0.000
G50 Disorders of trigeminal nerve	0.605	0.394	0.001
S61.1 Open wound of finger(s) with damage to nail	0.606	0.394	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.605	0.394	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.605	0.395	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.605	0.395	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.605	0.395	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.605	0.395	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.605	0.395	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.605	0.395	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.605	0.395	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.605	0.395	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.605	0.395	0.000
T36 Poisoning by systemic antibiotics	0.605	0.395	0.000
S81.7 Multiple open wounds of lower leg	0.604	0.396	0.000
O47.9 False labour, unspecified	0.602	0.398	0.000
D75 Other diseases of blood and blood-forming organs	0.602	0.398	0.000
S05 Injury of eye and orbit	0.602	0.398	0.000
M85 Other disorders of bone density and structure	0.601	0.398	0.000
M83 Adult osteomalacia	0.601	0.398	0.000
M82 Osteoporosis in diseases classified elsewhere	0.601	0.398	0.000
O73.0 Retained placenta, without haemorrhage	0.601	0.399	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.600	0.399	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.598	0.402	0.000
M70-M79 Other soft tissue disorders	0.598	0.402	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.596	0.404	0.000
S69 Other and unspecified injuries of wrist and hand	0.595	0.405	0.000
S65 Injury of blood vessels at wrist and hand level	0.595	0.405	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.595	0.405	0.000
G90-G99 Other disorders of the nervous system	0.593	0.407	0.000
S61.0 Open wound of finger(s) without damage to nail	0.591	0.409	0.000
G70-G73 Diseases of myoneural junction and muscle	0.591	0.409	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.591	0.409	0.000
S27.0 Traumatic pneumothorax	0.591	0.409	0.000
S22.2 Fracture of sternum	0.589	0.411	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.589	0.411	0.000
T98 Sequelae of other and unspecified effects of external causes	0.588	0.411	0.000
T95 Sequelae of burns, corrosions and frostbite	0.588	0.411	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.588	0.411	0.000
T92 Sequelae of injuries of upper limb	0.588	0.411	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.588	0.411	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.588	0.411	0.000
M88 Paget's disease of bone [osteitis deformans]	0.588	0.412	0.000
G35 Multiple sclerosis	0.586	0.414	0.000
Y59 Other and unspecified vaccines and biological substances	0.585	0.414	0.000
Y58 Bacterial vaccines	0.585	0.414	0.000
Y57 Other and unspecified drugs and medicaments	0.585	0.414	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.585	0.414	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.585	0.414	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.585	0.414	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.585	0.414	0.000
Y52 Agents primarily affecting the cardiovascular system	0.585	0.414	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.585	0.414	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.585	0.414	0.000
Y48 Anaesthetics and therapeutic gases	0.585	0.414	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.585	0.414	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.585	0.414	0.000
M90 Osteopathies in diseases classified elsewhere	0.585	0.415	0.000
T90 Sequelae of injuries of head	0.584	0.416	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.583	0.417	0.000
S81.8 Open wound of other parts of lower leg	0.583	0.417	0.000
S22.0 Fracture of thoracic vertebra	0.579	0.420	0.000
M87 Osteonecrosis	0.579	0.420	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.579	0.421	0.000
M89 Other disorders of bone	0.579	0.421	0.000
M06 Other rheumatoid arthritis	0.577	0.423	0.000
S82.20 Fracture of shaft of tibia (closed)	0.577	0.423	0.000
T43.2 Other and unspecified antidepressants	0.576	0.423	0.000
D69 Purpura and other haemorrhagic conditions	0.576	0.424	0.000
M47.2 Other spondylosis with radiculopathy	0.576	0.424	0.000
C56 Malignant neoplasm of ovary	0.575	0.425	0.000
S51 Open wound of forearm	0.575	0.425	0.000
S82.3 Fracture of lower end of tibia	0.573	0.427	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.573	0.427	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.572	0.428	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.571	0.428	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.571	0.428	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.571	0.428	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.571	0.428	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.571	0.428	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.571	0.428	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.571	0.428	0.000
S82.00 Fracture of patella (closed)	0.571	0.429	0.000
M50 Cervical disk disorders	0.571	0.429	0.000
D60-D64 Aplastic and other anaemias	0.571	0.429	0.000
S01 Open wound of head	0.571	0.429	0.000
T14 Injury of unspecified body region	0.569	0.430	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.568	0.432	0.000
D74 Methaemoglobinaemia	0.568	0.432	0.000
D72 Other disorders of white blood cells	0.568	0.432	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.568	0.432	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.568	0.432	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.567	0.432	0.000
D45 Polycythaemia vera	0.567	0.433	0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.567	0.433	0.000
S22.9 Fracture of bony thorax, part unspecified	0.567	0.433	0.000
S22.8 Fracture of other parts of bony thorax	0.567	0.433	0.000
S22.5 Flail chest	0.567	0.433	0.000
S22.1 Multiple fractures of thoracic spine	0.567	0.433	0.000
B95-B98 Bacterial, viral and other infectious agents	0.565	0.435	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.565	0.435	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.564	0.436	0.000
S64 Injury of nerves at wrist and hand level	0.564	0.436	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.563	0.436	0.000
D50-D53 Nutritional anaemias	0.563	0.437	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.563	0.437	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.562	0.438	0.000
O66.9 Obstructed labour, unspecified	0.562	0.438	0.000
O66.8 Other specified obstructed labour	0.562	0.438	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.562	0.438	0.000
O66.4 Failed trial of labour, unspecified	0.562	0.438	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.562	0.438	0.000
O66.2 Obstructed labour due to unusually large foetus	0.562	0.438	0.000
O66.1 Obstructed labour due to locked twins	0.562	0.438	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.562	0.438	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.560	0.440	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.558	0.442	0.000
O80.9 Single spontaneous delivery, unspecified	0.557	0.442	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.556	0.444	0.000
M49 Spondylopathies in diseases classified elsewhere	0.555	0.445	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.555	0.445	0.000
S00 Superficial injury of head	0.555	0.445	0.000
O15 Eclampsia	0.555	0.445	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.555	0.445	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.555	0.445	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.555	0.445	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.555	0.445	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.554	0.446	0.000
C34 Malignant neoplasm of bronchus and lung	0.554	0.446	0.000
V23.4 Driver injured in traffic accident	0.554	0.446	0.000
D68 Other coagulation defects	0.553	0.447	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.552	0.448	0.000
S22.40 Multiple fractures of ribs (closed)	0.552	0.448	0.000
O75.9 Complication of labour and delivery, unspecified	0.552	0.448	0.000
O75.8 Other specified complications of labour and delivery	0.552	0.448	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.552	0.448	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.552	0.448	0.000
O75.4 Other complications of obstetric surgery and procedures	0.552	0.448	0.000
O75.3 Other infection during labour	0.552	0.448	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.552	0.448	0.000
O75.1 Shock during or following labour and delivery	0.552	0.448	0.000
O75.0 Maternal distress during labour and delivery	0.552	0.448	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.551	0.449	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.550	0.450	0.000
M86 Osteomyelitis	0.549	0.450	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.549	0.451	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.549	0.451	0.000
S08 Traumatic amputation of part of head	0.548	0.452	0.000
S07 Crushing injury of head	0.548	0.452	0.000
S04 Injury of cranial nerves	0.548	0.452	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.548	0.452	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.548	0.452	0.000
T32 Corrosions classified according to extent of body surface involved	0.548	0.452	0.000
T30 Burn and corrosion, body region unspecified	0.548	0.452	0.000
T29 Burns and corrosions of multiple body regions	0.548	0.452	0.000
S50 Superficial injury of forearm	0.546	0.454	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.546	0.454	0.000
M41 Scoliosis	0.546	0.454	0.000
S12 Fracture of neck	0.545	0.455	0.000
Chapter V Mental and behavioural disorders	0.544	0.455	0.000
W06 Fall involving bed	0.544	0.456	0.000
C64-C68 Malignant neoplasms of urinary tract	0.544	0.456	0.000
W08 Fall involving other furniture	0.544	0.456	0.000
S40 Superficial injury of shoulder and upper arm	0.543	0.457	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.543	0.457	0.000
O97 Death from sequelae of direct obstetric causes	0.543	0.457	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.543	0.457	0.000
O95 Obstetric death of unspecified cause	0.543	0.457	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.543	0.457	0.000
S20.7 Multiple superficial injuries of thorax	0.542	0.458	0.000
S20.4 Other superficial injuries of back wall of thorax	0.542	0.458	0.000
S20.3 Other superficial injuries of front wall of thorax	0.542	0.458	0.000
S20.2 Contusion of thorax	0.542	0.458	0.000
S20.1 Other and unspecified superficial injuries of breast	0.542	0.458	0.000
S20.0 Contusion of breast	0.542	0.458	0.000
Q28 Other congenital malformations of circulatory system	0.541	0.459	0.000
M19 Other arthrosis	0.541	0.459	0.000
M94 Other disorders of cartilage	0.540	0.460	0.000
M17.3 Other posttraumatic gonarthrosis	0.540	0.460	0.000
O82.0 Delivery by elective Caesarean section	0.539	0.461	0.000
D46 Myelodysplastic syndromes	0.539	0.461	0.000
M81.8 Other osteoporosis	0.538	0.461	0.000
M81.6 Localised osteoporosis [Lequesne]	0.538	0.461	0.000
M81.5 Idiopathic osteoporosis	0.538	0.461	0.000
M81.4 Drug-induced osteoporosis	0.538	0.461	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.538	0.461	0.000
M81.2 Osteoporosis of disuse	0.538	0.461	0.000
M81.1 Postoophorectomy osteoporosis	0.538	0.461	0.000
M81.0 Postmenopausal osteoporosis	0.538	0.461	0.000
H65-H75 Diseases of middle ear and mastoid	0.537	0.462	0.000
G20-G26 Extrapyramidal and movement disorders	0.537	0.463	0.000
S82.60 Fracture of lateral malleolus (closed)	0.537	0.463	0.000
S59 Other and unspecified injuries of forearm	0.537	0.463	0.000
S58 Traumatic amputation of forearm	0.537	0.463	0.000
S57 Crushing injury of forearm	0.537	0.463	0.000
S56 Injury of muscle and tendon at forearm level	0.537	0.463	0.000
S55 Injury of blood vessels at forearm level	0.537	0.463	0.000
S54 Injury of nerves at forearm level	0.537	0.463	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.537	0.463	0.000
M18 Arthrosis of first carpometacarpal joint	0.537	0.463	0.000
S52 Fracture of forearm	0.537	0.463	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.536	0.464	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.536	0.464	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.536	0.464	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations