TreeWAS – Variant ID: rs1387389

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T84.1 Mechanical complication of internal fixation device of bones of limb	0.053	0.947	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.049	0.951	0.000
M20.5 Other deformities of toe(s) (acquired)	0.048	0.952	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.045	0.955	0.000
D23.3 Skin of other and unspecified parts of face	0.043	0.957	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.040	0.960	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.038	0.962	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.036	0.964	0.000
M20.0 Deformity of finger(s)	0.034	0.966	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.033	0.967	0.000
M20 Acquired deformities of fingers and toes	0.033	0.967	0.000
M20.1 Hallux valgus (acquired)	0.031	0.969	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.026	0.974	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.023	0.977	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.020	0.980	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.018	0.982	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.017	0.983	0.000
F31 Bipolar affective disorder	0.000	0.984	0.016
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.984	0.016
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.984	0.016
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.985	0.015
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.986	0.014
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.986	0.014
H40.2 Primary angle-closure glaucoma	0.014	0.986	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.986	0.013
F31.8 Other bipolar affective disorders	0.000	0.987	0.013
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.988	0.012
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.988	0.012
M20.4 Other hammer toe(s) (acquired)	0.011	0.989	0.000
N48.8 Other specified disorders of penis	0.000	0.990	0.010
M20.3 Other deformity of hallux (acquired)	0.009	0.990	0.000
G62.9 Polyneuropathy, unspecified	0.009	0.991	0.000
H33.2 Serous retinal detachment	0.000	0.992	0.008
R94.3 Abnormal results of cardiovascular function studies	0.006	0.994	0.000
R23.3 Spontaneous ecchymoses	0.000	0.995	0.005
N75.1 Abscess of Bartholin's gland	0.005	0.995	0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.004	0.996	0.000
Z37.2 Twins, both liveborn	0.004	0.996	0.000
J86.9 Pyothorax without fistula	0.000	0.996	0.004
F31.9 Bipolar affective disorder, unspecified	0.000	0.996	0.004
M43.02 Spondylolysis (Cervical region)	0.000	0.996	0.004
I86.8 Varicose veins of other specified sites	0.004	0.996	0.000
R23 Other skin changes	0.000	0.996	0.004
R23.2 Flushing	0.000	0.996	0.004
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.000	0.996	0.004
R23.8 Other and unspecified skin changes	0.000	0.997	0.003
R23.4 Changes in skin texture	0.000	0.997	0.003
T90.4 Sequelae of injury of eye and orbit	0.003	0.997	0.000
N72 Inflammatory disease of cervix uteri	0.003	0.997	0.000
F23.9 Acute and transient psychotic disorder, unspecified	0.003	0.997	0.000
M25.74 Osteophyte (Hand)	0.000	0.997	0.003
K76.9 Liver disease, unspecified	0.003	0.997	0.000
C45.0 Mesothelioma of pleura	0.000	0.997	0.003
F23.3 Other acute predominantly delusional psychotic disorders	0.003	0.997	0.000
F23 Acute and transient psychotic disorders	0.003	0.997	0.000
N75 Diseases of Bartholin's gland	0.003	0.997	0.000
R23.0 Cyanosis	0.000	0.997	0.003
F25.9 Schizoaffective disorder, unspecified	0.003	0.997	0.000
C45.7 Mesothelioma of other sites	0.000	0.997	0.003
Z97.5 Presence of (intra-uterine) contraceptive device	0.003	0.997	0.000
N43.3 Hydrocele, unspecified	0.003	0.997	0.000
R23.1 Pallor	0.000	0.997	0.003
F25 Schizoaffective disorders	0.003	0.997	0.000
F52.2 Failure of genital response	0.000	0.997	0.003
C80.0 Malignant neoplasm, primary site unknown, so stated	0.003	0.997	0.000
F25.0 Schizoaffective disorder, manic type	0.003	0.997	0.000
C45 Mesothelioma	0.000	0.997	0.003
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.003	0.997	0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.003	0.997	0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.003	0.997	0.000
S42.10 Fracture of scapula (closed)	0.000	0.997	0.003
F25.1 Schizoaffective disorder, depressive type	0.002	0.997	0.000
N48.0 Leukoplakia of penis	0.000	0.997	0.003
F23.8 Other acute and transient psychotic disorders	0.002	0.997	0.000
F23.2 Acute schizophrenia-like psychotic disorder	0.002	0.997	0.000
N75.9 Disease of Bartholin's gland, unspecified	0.002	0.997	0.000
N75.8 Other diseases of Bartholin's gland	0.002	0.997	0.000
G62 Other polyneuropathies	0.002	0.997	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.002	0.998	0.000
N75.0 Cyst of Bartholin's gland	0.002	0.998	0.000
C45.9 Mesothelioma, unspecified	0.000	0.998	0.002
F25.2 Schizoaffective disorder, mixed type	0.002	0.998	0.000
I34.0 Mitral (valve) insufficiency	0.000	0.998	0.002
S93.1 Dislocation of toe(s)	0.002	0.998	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.002	0.998	0.000
N48 Other disorders of penis	0.000	0.998	0.002
F25.8 Other schizoaffective disorders	0.002	0.998	0.000
C45.2 Mesothelioma of pericardium	0.000	0.998	0.002
C45.1 Mesothelioma of peritoneum	0.000	0.998	0.002
N48.4 Impotence of organic origin	0.000	0.998	0.002
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.998	0.002
G30.9 Alzheimer's disease, unspecified	0.002	0.998	0.000
G62.0 Drug-induced polyneuropathy	0.002	0.998	0.000
T90.8 Sequelae of other specified injuries of head	0.002	0.998	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.002	0.998	0.000
S82.81 Fractures of other parts of lower leg (open)	0.000	0.998	0.002
I78.1 Naevus, nonneoplastic	0.002	0.998	0.000
A41.1 Septicaemia due to other specified staphylococcus	0.000	0.998	0.002
K55.2 Angiodysplasia of colon	0.002	0.998	0.000
M43.0 Spondylolysis	0.000	0.998	0.002
N50.0 Atrophy of testis	0.002	0.998	0.000
T90 Sequelae of injuries of head	0.002	0.998	0.000
M43.06 Spondylolysis (Lumbar region)	0.000	0.998	0.002
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.998	0.002
G62.2 Polyneuropathy due to other toxic agents	0.002	0.998	0.000
T94.1 Sequelae of injuries, not specified by body region	0.002	0.998	0.000
N71.1 Chronic inflammatory disease of uterus	0.002	0.998	0.000
N86 Erosion and ectropion of cervix uteri	0.000	0.998	0.002
T90.1 Sequelae of open wound of head	0.002	0.998	0.000
Z36.9 Antenatal screening, unspecified	0.002	0.998	0.000
N41.1 Chronic prostatitis	0.000	0.998	0.002
Z30.1 Insertion of (intra-uterine) contraceptive device	0.002	0.998	0.000
N71 Inflammatory disease of uterus, except cervix	0.002	0.998	0.000
N48.9 Disorder of penis, unspecified	0.000	0.998	0.002
G62.1 Alcoholic polyneuropathy	0.002	0.998	0.000
N70.1 Chronic salpingitis and oophoritis	0.002	0.998	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.000	0.998	0.002
N70-N77 Inflammatory diseases of female pelvic organs	0.002	0.998	0.000
N71.9 Inflammatory disease of uterus, unspecified	0.002	0.998	0.000
H53.0 Amblyopia ex anopsia	0.002	0.998	0.000
X41.9 Unspecified place	0.002	0.998	0.000
L81.9 Disorder of pigmentation, unspecified	0.002	0.998	0.000
T90.0 Sequelae of superficial injury of head	0.002	0.998	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.002	0.998	0.000
N48.3 Priapism	0.000	0.998	0.002
S01.7 Multiple open wounds of head	0.000	0.998	0.002
Z71.9 Counselling, unspecified	0.002	0.998	0.000
H35.3 Degeneration of macula and posterior pole	0.000	0.998	0.002
N02.9 Unspecified	0.002	0.998	0.000
M51.9 Intervertebral disk disorder, unspecified	0.002	0.998	0.000
M43.08 Spondylolysis (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M43.07 Spondylolysis (Lumbosacral region)	0.000	0.998	0.002
M43.05 Spondylolysis (Thoracolumbar region)	0.000	0.998	0.002
M43.04 Spondylolysis (Thoracic region)	0.000	0.998	0.002
M43.03 Spondylolysis (Cervicothoracic region)	0.000	0.998	0.002
M43.01 Spondylolysis (Occipito-atlanto-axial region)	0.000	0.998	0.002
M43.00 Spondylolysis (Multiple sites in spine)	0.000	0.998	0.002
E22.0 Acromegaly and pituitary gigantism	0.000	0.998	0.002
T90.3 Sequelae of injury of cranial nerves	0.002	0.998	0.000
J86 Pyothorax	0.000	0.998	0.002
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.002	0.998	0.000
G62.8 Other specified polyneuropathies	0.000	0.998	0.001
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.002	0.998	0.000
O81.4 Vacuum extractor delivery	0.000	0.998	0.002
Z32.1 Pregnancy confirmed	0.002	0.998	0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.002	0.998	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.002	0.998	0.000
N48.5 Ulcer of penis	0.000	0.998	0.002
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.002	0.998	0.000
N70 Salpingitis and oophoritis	0.002	0.998	0.000
F28 Other nonorganic psychotic disorders	0.001	0.998	0.000
F24 Induced delusional disorder	0.001	0.998	0.000
F21 Schizotypal disorder	0.001	0.998	0.000
S05.9 Injury of eye and orbit, part unspecified	0.000	0.998	0.002
T94 Sequelae of injuries involving multiple and unspecified body regions	0.002	0.998	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.002
C48.0 Retroperitoneum	0.000	0.998	0.002
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.002	0.998	0.000
Z39.1 Care and examination of lactating mother	0.000	0.998	0.002
F20.5 Residual schizophrenia	0.001	0.998	0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.000	0.998	0.002
T93.2 Sequelae of other fractures of lower limb	0.002	0.998	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.000	0.998	0.002
D12.8 Rectum	0.000	0.998	0.002
M79.18 Myalgia (Other)	0.000	0.999	0.001
I42.0 Dilated cardiomyopathy	0.000	0.999	0.001
M21.3 Wrist or foot drop (acquired)	0.001	0.999	0.000
N74.8 Female pelvic inflammatory disorders in other diseases classified elsewhere	0.001	0.999	0.000
N74.4 Female chlamydial pelvic inflammatory disease	0.001	0.999	0.000
N74.3 Female gonococcal pelvic inflammatory disease	0.001	0.999	0.000
N74.2 Female syphilitic pelvic inflammatory disease	0.001	0.999	0.000
N74.1 Female tuberculous pelvic inflammatory disease	0.001	0.999	0.000
N74.0 Tuberculous infection of cervix uteri	0.001	0.999	0.000
F20 Schizophrenia	0.001	0.999	0.000
M43.09 Spondylolysis (Site unspecified)	0.000	0.999	0.001
I11.9 Hypertensive heart disease without (congestive) heart failure	0.001	0.999	0.000
Q05.9 Spina bifida, unspecified	0.001	0.999	0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.001	0.999	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.000	0.999	0.001
B25.9 Cytomegaloviral disease, unspecified	0.001	0.999	0.000
C48.2 Peritoneum, unspecified	0.000	0.999	0.001
F20.8 Other schizophrenia	0.001	0.999	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.001	0.999	0.000
W57.0 Home	0.000	0.999	0.001
N15.9 Renal tubulo-interstitial disease, unspecified	0.000	0.999	0.001
R94.0 Abnormal results of function studies of central nervous system	0.001	0.999	0.000
T94.0 Sequelae of injuries involving multiple body regions	0.001	0.999	0.000
C48.1 Specified parts of peritoneum	0.000	0.999	0.001
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.000	0.999	0.001
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.000	0.999	0.001
F52.7 Excessive sexual drive	0.000	0.999	0.001
F52.6 Nonorganic dyspareunia	0.000	0.999	0.001
F52.5 Nonorganic vaginismus	0.000	0.999	0.001
F52.4 Premature ejaculation	0.000	0.999	0.001
F52.3 Orgasmic dysfunction	0.000	0.999	0.001
F52.1 Sexual aversion and lack of sexual enjoyment	0.000	0.999	0.001
N71.0 Acute inflammatory disease of uterus	0.001	0.999	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.000	0.999	0.001
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.999	0.001
T90.9 Sequelae of unspecified injury of head	0.001	0.999	0.000
N43 Hydrocele and spermatocele	0.001	0.999	0.000
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.000	0.999	0.001
G30.8 Other Alzheimer's disease	0.001	0.999	0.000
T93 Sequelae of injuries of lower limb	0.001	0.999	0.000
F52.0 Lack or loss of sexual desire	0.000	0.999	0.001
R94.2 Abnormal results of pulmonary function studies	0.001	0.999	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.001	0.999	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.001	0.999	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.001	0.999	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.001	0.999	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.001	0.999	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.001	0.999	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.001	0.999	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.001	0.999	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.001	0.999	0.000
F20.6 Simple schizophrenia	0.001	0.999	0.000
F20.4 Postschizophrenic depression	0.001	0.999	0.000
F20.3 Undifferentiated schizophrenia	0.001	0.999	0.000
F20.2 Catatonic schizophrenia	0.001	0.999	0.000
F20.1 Hebephrenic schizophrenia	0.001	0.999	0.000
M20.2 Hallux rigidus	0.001	0.999	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.001	0.999	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.001	0.999	0.000
A87.9 Viral meningitis, unspecified	0.001	0.999	0.000
C21.1 Anal canal	0.001	0.999	0.000
G40.8 Other epilepsy	0.000	0.999	0.001
I46.9 Cardiac arrest, unspecified	0.000	0.999	0.001
N70.0 Acute salpingitis and oophoritis	0.001	0.999	0.000
N77.8 Vulvovaginal ulceration and inflammation in other diseases classified elsewhere	0.001	0.999	0.000
N77.0 Ulceration of vulva in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
R94 Abnormal results of function studies	0.001	0.999	0.000
M21.27 Flexion deformity (Ankle and foot)	0.001	0.999	0.000
N43.4 Spermatocele	0.001	0.999	0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.001	0.999	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.001	0.999	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.000	0.999	0.001
M21.24 Flexion deformity (Hand)	0.001	0.999	0.000
M70.32 Other bursitis of elbow-Upper arm	0.001	0.999	0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.000	0.999	0.001
G04.1 Tropical spastic paraplegia	0.000	0.999	0.001
G04.0 Acute disseminated encephalitis	0.000	0.999	0.001
N48.1 Balanoposthitis	0.000	0.999	0.001
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.001	0.999	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.000	0.999	0.001
H65.2 Chronic serous otitis media	0.001	0.999	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.999	0.001
M90.7 Fracture of bone in neoplastic disease	0.001	0.999	0.000
O47.9 False labour, unspecified	0.000	0.999	0.001
R93.6 Abnormal findings on diagnostic imaging of limbs	0.001	0.999	0.000
S42.1 Fracture of scapula	0.000	0.999	0.001
Y57.8 Other drugs and medicaments	0.001	0.999	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.001	0.999	0.000
M79.19 Myalgia (Site unspecified)	0.000	0.999	0.001
N43.1 Infected hydrocele	0.001	0.999	0.000
N43.0 Encysted hydrocele	0.001	0.999	0.000
K62.4 Stenosis of anus and rectum	0.000	0.999	0.001
T90.5 Sequelae of intracranial injury	0.001	0.999	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.001	0.999	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.001	0.999	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.001	0.999	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.001	0.999	0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.001	0.999	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.000	0.999	0.001
T80.2 Infections following infusion, transfusion and therapeutic injection	0.000	0.999	0.001
G09 Sequelae of inflammatory diseases of central nervous system	0.000	0.999	0.001
H71 Cholesteatoma of middle ear	0.001	0.999	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.001	0.999	0.000
N43.2 Other hydrocele	0.001	0.999	0.000
Q60.3 Renal hypoplasia, unilateral	0.001	0.999	0.000
S42.11 Fracture of scapula (open)	0.000	0.999	0.001
E22.1 Hyperprolactinaemia	0.000	0.999	0.001
G45.4 Transient global amnesia	0.000	0.999	0.001
J86.0 Pyothorax with fistula	0.000	0.999	0.001
N02.2 Diffuse membranous glomerulonephritis	0.001	0.999	0.000
N76.3 Subacute and chronic vulvitis	0.001	0.999	0.000
Q60.0 Renal agenesis, unilateral	0.001	0.999	0.000
W05.0 Home	0.000	0.999	0.001
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.000	0.999	0.001
C46 Kaposi's sarcoma	0.000	0.999	0.001
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.001	0.999	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.001	0.999	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.001	0.999	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.001	0.999	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.001	0.999	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.000	0.999	0.001
J31.2 Chronic pharyngitis	0.000	0.999	0.001
L50.0 Allergic urticaria	0.000	0.999	0.001
M51.4 Schmorl's nodes	0.001	0.999	0.000
Q07.0 Arnold-Chiari syndrome	0.001	0.999	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.001	0.999	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.001	0.999	0.000
R93 Abnormal findings on diagnostic imaging of other body structures	0.001	0.999	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.000	0.999	0.001
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.001	0.999	0.000
G40.9 Epilepsy, unspecified	0.000	0.999	0.001
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.999	0.001
T93.0 Sequelae of open wound of lower limb	0.001	0.999	0.000
F29 Unspecified nonorganic psychosis	0.001	0.999	0.000
G30 Alzheimer's disease	0.001	0.999	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.001	0.999	0.000
M21.26 Flexion deformity (Lower leg)	0.001	0.999	0.000
S62.50 Fracture of thumb (closed)	0.001	0.999	0.000
B17.1 Acute hepatitis C	0.001	0.999	0.000
L71.9 Rosacea, unspecified	0.001	0.999	0.000
M21.2 Flexion deformity	0.001	0.999	0.000
M95.0 Acquired deformity of nose	0.001	0.999	0.000
S36.1 Injury of liver or gallbladder	0.001	0.999	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.001	0.999	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.001	0.999	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.001	0.999	0.000
C46.9 Kaposi's sarcoma, unspecified	0.000	0.999	0.001
C46.8 Kaposi's sarcoma of multiple organs	0.000	0.999	0.001
C46.7 Kaposi's sarcoma of other sites	0.000	0.999	0.001
C46.3 Kaposi's sarcoma of lymph nodes	0.000	0.999	0.001
C46.2 Kaposi's sarcoma of palate	0.000	0.999	0.001
C46.1 Kaposi's sarcoma of soft tissue	0.000	0.999	0.001
C46.0 Kaposi's sarcoma of skin	0.000	0.999	0.001
C47.9 Peripheral nerves and autonomic nervous system, unspecified	0.000	0.999	0.001
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system	0.000	0.999	0.001
C47.6 Peripheral nerves of trunk, unspecified	0.000	0.999	0.001
C47.5 Peripheral nerves of pelvis	0.000	0.999	0.001
C47.4 Peripheral nerves of abdomen	0.000	0.999	0.001
C47.3 Peripheral nerves of thorax	0.000	0.999	0.001
C47.2 Peripheral nerves of lower limb, including hip	0.000	0.999	0.001
C47.1 Peripheral nerves of upper limb, including shoulder	0.000	0.999	0.001
C47.0 Peripheral nerves of head, face and neck	0.000	0.999	0.001
F43.2 Adjustment disorders	0.001	0.999	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.000	0.999	0.001
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.000	0.999	0.001
T78.0 Anaphylactic shock due to adverse food reaction	0.001	0.999	0.000
H65 Nonsuppurative otitis media	0.001	0.999	0.000
T80.6 Other serum reactions	0.000	0.999	0.001
T80.5 Anaphylactic shock due to serum	0.000	0.999	0.001
T80.4 Rh incompatibility reaction	0.000	0.999	0.001
T80.3 ABO incompatibility reaction	0.000	0.999	0.001
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.000	0.999	0.001
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.001	0.999	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.001	0.999	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.001	0.999	0.000
Z93.5 Cystostomy status	0.001	0.999	0.000
F22 Persistent delusional disorders	0.001	0.999	0.000
M21.29 Flexion deformity (Site unspecified)	0.001	0.999	0.000
M21.28 Flexion deformity (Other)	0.001	0.999	0.000
M21.23 Flexion deformity (Forearm)	0.001	0.999	0.000
M21.22 Flexion deformity (Upper arm)	0.001	0.999	0.000
M21.21 Flexion deformity (Shoulder region)	0.001	0.999	0.000
M21.20 Flexion deformity (Multiple sites)	0.001	0.999	0.000
M70.46 Prepatellar bursitis-Lower Leg	0.001	0.999	0.000
M94.89 Other specified disorders of cartilage (Site unspecified)	0.001	0.999	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.001	0.999	0.000
S36.11 Injury of liver or gallbladder (with open wound into cavity)	0.001	0.999	0.000
G41.9 Status epilepticus, unspecified	0.000	0.999	0.001
R94.7 Abnormal results of other endocrine function studies	0.001	0.999	0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.000	0.999	0.001
T92.8 Sequelae of other specified injuries of upper limb	0.001	0.999	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.001	0.999	0.000
X41.2 School, other institution and public administrative area	0.001	0.999	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.001	0.999	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.001	0.999	0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.001	0.999	0.000
D44.3 Pituitary gland	0.000	0.999	0.001
D72.8 Other specified disorders of white blood cells	0.001	0.999	0.000
H65.1 Other acute nonsuppurative otitis media	0.001	0.999	0.000
N48.6 Balanitis xerotica obliterans	0.000	0.999	0.001
N48.2 Other inflammatory disorders of penis	0.000	0.999	0.001
R94.4 Abnormal results of kidney function studies	0.001	0.999	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.000	0.999	0.001
Y52.3 Coronary vasodilators, not elsewhere classified	0.001	0.999	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.001	0.999	0.000
R80 Isolated proteinuria	0.001	0.999	0.000
S05 Injury of eye and orbit	0.000	0.999	0.001
F22.8 Other persistent delusional disorders	0.001	0.999	0.000
N02.0 Minor glomerular abnormality	0.001	0.999	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.001	0.999	0.000
W57.8 Other specified place	0.000	0.999	0.001
X41.0 Home	0.001	0.999	0.000
X41.8 Other specified place	0.001	0.999	0.000
X41.7 Farm	0.001	0.999	0.000
X41.6 Industrial and construction area	0.001	0.999	0.000
X41.5 Trade and service area	0.001	0.999	0.000
X41.4 Street and highway	0.001	0.999	0.000
X41.3 Sports and athletics area	0.001	0.999	0.000
X41.1 Residential institution	0.001	0.999	0.000
Q05 Spina bifida	0.001	0.999	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.001	0.999	0.000
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.001	0.999	0.000
H33.1 Retinoschisis and retinal cysts	0.000	0.999	0.001
I84.2 Internal haemorrhoids without complication	0.001	0.999	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.999	0.001
Q60.6 Potter's syndrome	0.001	0.999	0.000
Q60.5 Renal hypoplasia, unspecified	0.001	0.999	0.000
Q60.4 Renal hypoplasia, bilateral	0.001	0.999	0.000
Q60.2 Renal agenesis, unspecified	0.001	0.999	0.000
Q60.1 Renal agenesis, bilateral	0.001	0.999	0.000
R94.6 Abnormal results of thyroid function studies	0.001	0.999	0.000
S05.7 Avulsion of eye	0.000	0.999	0.001
S05.6 Penetrating wound of eyeball without foreign body	0.000	0.999	0.001
S05.4 Penetrating wound of orbit with or without foreign body	0.000	0.999	0.001
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.999	0.001
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
X41.08 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, antiparkinsonism and psychotropic drugs, not elsewhere classified , Home ,While engaged in other specified activities	0.001	0.999	0.000
G30.1 Alzheimer's disease with late onset	0.001	0.999	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.999	0.001
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
I98.0 Cardiovascular syphilis	0.000	0.999	0.001
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.001	0.999	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.001	0.999	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.001	0.999	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.001	0.999	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.001	0.999	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.001	0.999	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.001	0.999	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.001	0.999	0.000
Q07.8 Other specified congenital malformations of nervous system	0.001	0.999	0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.001	0.999	0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.000	0.999	0.001
E22 Hyperfunction of pituitary gland	0.000	0.999	0.001
M79.84 Other specified soft tissue disorders (Hand)	0.001	0.999	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.999	0.001
E22.8 Other hyperfunction of pituitary gland	0.000	0.999	0.001
K25.4 Chronic or unspecified with haemorrhage	0.001	0.999	0.000
L50.1 Idiopathic urticaria	0.000	0.999	0.001
M17.3 Other posttraumatic gonarthrosis	0.001	0.999	0.000
S05.8 Other injuries of eye and orbit	0.000	0.999	0.001
T42.1 Iminostilbenes	0.001	0.999	0.000
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.001	0.999	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.000	0.999	0.001
N02 Recurrent and persistent haematuria	0.001	0.999	0.000
Q07 Other congenital malformations of nervous system	0.001	0.999	0.000
T95 Sequelae of burns, corrosions and frostbite	0.001	0.999	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.001	0.999	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.001	0.999	0.000
A16.2 Tuberculosis of lung, without mention of bacteriological or histological confirmation	0.001	0.999	0.000
C16.2 Body of stomach	0.001	0.999	0.000
F22.9 Persistent delusional disorder, unspecified	0.001	0.999	0.000
F34.1 Dysthymia	0.000	0.999	0.001
G06.0 Intracranial abscess and granuloma	0.000	0.999	0.001
M51.3 Other specified intervertebral disk degeneration	0.001	0.999	0.000
N02.7 Diffuse crescentic glomerulonephritis	0.001	0.999	0.000
N02.6 Dense deposit disease	0.001	0.999	0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis	0.001	0.999	0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis	0.001	0.999	0.000
N02.1 Focal and segmental glomerular lesions	0.001	0.999	0.000
Q07.9 Congenital malformation of nervous system, unspecified	0.001	0.999	0.000
T95.9 Sequelae of unspecified burn, corrosion and frostbite	0.001	0.999	0.000
T95.8 Sequelae of other specified burn, corrosion and frostbite	0.001	0.999	0.000
T95.4 Sequelae of burn and corrosion classifiable only according to extent of body surface involved	0.001	0.999	0.000
T95.3 Sequelae of burn, corrosion and frostbite of lower limb	0.001	0.999	0.000
T95.0 Sequelae of burn, corrosion and frostbite of head and neck	0.001	0.999	0.000
A87.0 Enteroviral meningitis	0.001	0.999	0.000
H65.4 Other chronic nonsuppurative otitis media	0.001	0.999	0.000
H65.0 Acute serous otitis media	0.001	0.999	0.000
I78.9 Disease of capillaries, unspecified	0.001	0.999	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.001	0.999	0.000
N02.3 Diffuse mesangial proliferative glomerulonephritis	0.001	0.999	0.000
O81.3 Other and unspecified forceps delivery	0.000	0.999	0.001
Q61.4 Renal dysplasia	0.001	0.999	0.000
R94.8 Abnormal results of function studies of other organs and systems	0.001	0.999	0.000
B15.9 Hepatitis A without hepatic coma	0.001	0.999	0.000
H53.1 Subjective visual disturbances	0.001	0.999	0.000
L50.8 Other urticaria	0.000	0.999	0.001
N41.9 Inflammatory disease of prostate, unspecified	0.000	0.999	0.001
O22.4 Haemorrhoids in pregnancy	0.000	0.999	0.001
Q05.4 Unspecified spina bifida with hydrocephalus	0.001	0.999	0.000
Y43.1 Antineoplastic antimetabolites	0.000	0.999	0.001
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified	0.001	0.999	0.000
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region	0.001	0.999	0.000
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.001	0.999	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.001	0.999	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.001	0.999	0.000
O81.5 Delivery by combination of forceps and vacuum extractor	0.000	0.999	0.001
O81.2 Mid-cavity forceps with rotation	0.000	0.999	0.001
O81.1 Mid-cavity forceps delivery	0.000	0.999	0.001
Q03.0 Malformations of aqueduct of Sylvius	0.001	0.999	0.000
Q61.2 Polycystic kidney, adult type	0.001	0.999	0.000
T93.1 Sequelae of fracture of femur	0.001	0.999	0.000
M51 Other intervertebral disk disorders	0.001	0.999	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.001	0.999	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.001	0.999	0.000
W57.99 Bitten or stung by nonvenomous insect and other nonvenomous arthropods: Unspecified place: During unspecified activity	0.000	0.999	0.001
A16.9 Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation	0.001	0.999	0.000
A87.8 Other viral meningitis	0.001	0.999	0.000
A87.2 Lymphocytic choriomeningitis	0.001	0.999	0.000
A87.1 Adenoviral meningitis	0.001	0.999	0.000
F20.0 Paranoid schizophrenia	0.001	0.999	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.999	0.001
F34.8 Other persistent mood [affective] disorders	0.000	0.999	0.001
F34.0 Cyclothymia	0.000	0.999	0.001
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.000	0.999	0.001
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.999	0.001
M22.0 Recurrent dislocation of patella	0.001	0.999	0.000
O81.0 Low forceps delivery	0.000	0.999	0.001
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.001	0.999	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.001	0.999	0.000
W57.9 Unspecified place	0.000	0.999	0.001
W57.7 Farm	0.000	0.999	0.001
W57.6 Industrial and construction area	0.000	0.999	0.001
W57.5 Trade and service area	0.000	0.999	0.001
W57.4 Street and highway	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations