TreeWAS – Variant ID: rs138869894

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	0.761	0.239	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.736	0.264	0.000
Chapter XXI Factors influencing health status and contact with health services	0.732	0.268	0.000
Chapter XIV Diseases of the genitourinary system	0.731	0.269	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.729	0.271	0.000
M05-M14 Inflammatory polyarthropathies	0.721	0.279	0.000
N80-N98 Noninflammatory disorders of female genital tract	0.720	0.280	0.000
Chapter VI Diseases of the nervous system	0.719	0.281	0.000
Z00-Z13 Persons encountering health services for examination and investigation	0.710	0.290	0.000
M13 Other arthritis	0.700	0.300	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.690	0.310	0.000
Chapter II Neoplasms	0.689	0.311	0.000
M13.9 Arthritis, unspecified	0.686	0.314	0.000
Z12 Special screening examination for neoplasms	0.676	0.323	0.000
M13.99 Arthritis, unspecified (Site unspecified)	0.675	0.325	0.000
Z13 Special screening examination for other diseases and disorders	0.665	0.335	0.000
Chapter I Certain infectious and parasitic diseases	0.665	0.335	0.000
L03 Cellulitis	0.665	0.335	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.661	0.339	0.000
Z12.1 Special screening examination for neoplasm of intestinal tract	0.653	0.347	0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.651	0.349	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.650	0.350	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.644	0.356	0.000
D10-D36 Benign neoplasms	0.644	0.356	0.000
N92 Excessive, frequent and irregular menstruation	0.643	0.357	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.641	0.359	0.000
M80-M85 Disorders of bone density and structure	0.632	0.368	0.000
Z80 Family history of malignant neoplasm	0.631	0.369	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.628	0.372	0.000
L03.1 Cellulitis of other parts of limb	0.619	0.381	0.000
N81 Female genital prolapse	0.619	0.381	0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.616	0.384	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.613	0.387	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.610	0.390	0.000
Chapter X Diseases of the respiratory system	0.608	0.392	0.000
M10 Gout	0.598	0.402	0.000
N95 Menopausal and other perimenopausal disorders	0.597	0.403	0.000
G20-G26 Extrapyramidal and movement disorders	0.595	0.404	0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.595	0.405	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.588	0.412	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.586	0.414	0.000
Z83 Family history of other specific disorders	0.586	0.414	0.000
Z13.6 Special screening examination for cardiovascular disorders	0.583	0.416	0.000
Z80.0 Family history of malignant neoplasm of digestive organs	0.577	0.423	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.576	0.424	0.000
M65-M68 Disorders of synovium and tendon	0.575	0.425	0.000
M86-M90 Other osteopathies	0.574	0.426	0.000
N92.0 Excessive and frequent menstruation with regular cycle	0.572	0.428	0.000
J40-J47 Chronic lower respiratory diseases	0.572	0.428	0.000
Z98 Other postsurgical states	0.571	0.428	0.000
N94.1 Dyspareunia	0.571	0.429	0.000
B95-B98 Bacterial, viral and other infectious agents	0.571	0.429	0.000
Z02 Examination and encounter for administrative purposes	0.568	0.431	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.567	0.433	0.000
Chapter VIII Diseases of the ear and mastoid process	0.566	0.434	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.560	0.440	0.000
M81 Osteoporosis without pathological fracture	0.558	0.442	0.000
N00-N08 Glomerular diseases	0.557	0.443	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.557	0.443	0.000
L40-L45 Papulosquamous disorders	0.556	0.444	0.000
L03.3 Cellulitis of trunk	0.556	0.444	0.000
N90 Other noninflammatory disorders of vulva and perineum	0.556	0.444	0.000
N20-N23 Urolithiasis	0.555	0.445	0.000
Z90 Acquired absence of organs, not elsewhere classified	0.555	0.445	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.555	0.445	0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.554	0.446	0.000
D12.5 Sigmoid colon	0.551	0.449	0.000
S60-S69 Injuries to the wrist and hand	0.551	0.449	0.000
Z96 Presence of other functional implants	0.549	0.451	0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.548	0.452	0.000
N60-N64 Disorders of breast	0.548	0.452	0.000
J44 Other chronic obstructive pulmonary disease	0.546	0.454	0.000
Chapter XXII Codes for special purposes	0.545	0.454	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.545	0.454	0.000
M40-M43 Deforming dorsopathies	0.545	0.455	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.544	0.456	0.000
D25 Leiomyoma of uterus	0.543	0.457	0.000
G57 Mononeuropathies of lower limb	0.543	0.457	0.000
A30-A49 Other bacterial diseases	0.540	0.460	0.000
D17 Benign lipomatous neoplasm	0.539	0.461	0.000
Z13.1 Special screening examination for diabetes mellitus	0.539	0.461	0.000
M06 Other rheumatoid arthritis	0.539	0.461	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.538	0.462	0.000
G51 Facial nerve disorders	0.537	0.463	0.000
L03.9 Cellulitis, unspecified	0.536	0.464	0.000
N95.0 Postmenopausal bleeding	0.534	0.466	0.000
N81.2 Incomplete uterovaginal prolapse	0.533	0.466	0.000
D45 Polycythaemia vera	0.533	0.467	0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.533	0.467	0.000
N83.0 Follicular cyst of ovary	0.532	0.468	0.000
Z83.7 Family history of diseases of the digestive system	0.532	0.468	0.000
C15-C26 Malignant neoplasms of digestive organs	0.532	0.468	0.000
L50-L54 Urticaria and erythema	0.531	0.469	0.000
N89 Other noninflammatory disorders of vagina	0.530	0.470	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.529	0.471	0.000
L05 Pilonidal cyst	0.529	0.471	0.000
N92.1 Excessive and frequent menstruation with irregular cycle	0.528	0.472	0.000
N10-N16 Renal tubulo-interstitial diseases	0.528	0.472	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.527	0.472	0.000
M91-M94 Chondropathies	0.527	0.472	0.000
M60-M63 Disorders of muscles	0.527	0.472	0.000
M00-M03 Infectious arthropathies	0.527	0.472	0.000
N88 Other noninflammatory disorders of cervix uteri	0.526	0.474	0.000
Z87 Personal history of other diseases and conditions	0.525	0.475	0.000
N99-N99 Other disorders of the genitourinary system	0.524	0.475	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.524	0.476	0.000
L20-L30 Dermatitis and eczema	0.523	0.477	0.000
L10-L14 Bullous disorders	0.523	0.477	0.000
D12.0 Caecum	0.523	0.477	0.000
Z80.3 Family history of malignant neoplasm of breast	0.522	0.478	0.000
G50 Disorders of trigeminal nerve	0.521	0.479	0.000
N87 Dysplasia of cervix uteri	0.521	0.479	0.000
L60-L75 Disorders of skin appendages	0.519	0.481	0.000
Z04 Examination and observation for other reasons	0.518	0.482	0.000
Z90.4 Acquired absence of other parts of digestive tract	0.517	0.483	0.000
M14 Arthropathies in other diseases classified elsewhere	0.517	0.483	0.000
M12 Other specific arthropathies	0.517	0.483	0.000
M11 Other crystal arthropathies	0.517	0.483	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.517	0.483	0.000
M08 Juvenile arthritis	0.517	0.483	0.000
M07 Psoriatic and enteropathic arthropathies	0.517	0.483	0.000
M05 Seropositive rheumatoid arthritis	0.517	0.483	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.517	0.483	0.000
N81.5 Vaginal enterocele	0.517	0.483	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.517	0.483	0.000
N98 Complications associated with artificial fertilisation	0.516	0.483	0.000
N91 Absent, scanty and rare menstruation	0.516	0.483	0.000
N82 Fistulae involving female genital tract	0.516	0.483	0.000
N96 Habitual aborter	0.516	0.483	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.516	0.484	0.000
N25-N29 Other disorders of kidney and ureter	0.516	0.484	0.000
G70-G73 Diseases of myoneural junction and muscle	0.516	0.484	0.000
G30-G32 Other degenerative diseases of the nervous system	0.516	0.484	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.516	0.484	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.516	0.484	0.000
D12.7 Rectosigmoid junction	0.514	0.486	0.000
N81.6 Rectocele	0.513	0.487	0.000
N85 Other noninflammatory disorders of uterus, except cervix	0.513	0.487	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.513	0.487	0.000
M10.9 Gout, unspecified	0.510	0.490	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.509	0.491	0.000
Z10 Routine general health check-up of defined subpopulation	0.509	0.491	0.000
N80 Endometriosis	0.508	0.492	0.000
G20 Parkinson's disease	0.507	0.493	0.000
Z13.9 Special screening examination, unspecified	0.506	0.494	0.000
G40-G47 Episodic and paroxysmal disorders	0.505	0.495	0.000
M81.9 Osteoporosis, unspecified	0.505	0.495	0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.505	0.495	0.000
M45-M49 Spondylopathies	0.505	0.495	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.505	0.495	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.504	0.496	0.000
M13.8 Other specified arthritis	0.502	0.498	0.000
M13.1 Monoarthritis, not elsewhere classified	0.502	0.498	0.000
M13.0 Polyarthritis, unspecified	0.502	0.498	0.000
N72 Inflammatory disease of cervix uteri	0.502	0.498	0.000
S00-S09 Injuries to the head	0.502	0.498	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.502	0.498	0.000
M13.94 Arthritis, unspecified (Hand)	0.502	0.498	0.000
G90-G99 Other disorders of the nervous system	0.501	0.498	0.000
N84 Polyp of female genital tract	0.500	0.500	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.498	0.501	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.498	0.502	0.000
M50-M54 Other dorsopathies	0.498	0.502	0.000
N73 Other female pelvic inflammatory diseases	0.497	0.503	0.000
S70-S79 Injuries to the hip and thigh	0.497	0.503	0.000
D25.9 Leiomyoma of uterus, unspecified	0.495	0.505	0.000
L04 Acute lymphadenitis	0.494	0.505	0.000
L01 Impetigo	0.494	0.505	0.000
L00 Staphylococcal scalded skin syndrome	0.494	0.505	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.494	0.506	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.494	0.506	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.494	0.506	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.494	0.506	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.494	0.506	0.000
Z98.0 Intestinal bypass and anastomosis status	0.493	0.507	0.000
D12.2 Ascending colon	0.493	0.507	0.000
M13.98 Arthritis, unspecified (Other)	0.492	0.508	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.492	0.508	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.492	0.508	0.000
M13.93 Arthritis, unspecified (Forearm)	0.492	0.508	0.000
M13.92 Arthritis, unspecified (Upper arm)	0.492	0.508	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.492	0.508	0.000
O60-O75 Complications of labour and delivery	0.490	0.510	0.000
M13.96 Arthritis, unspecified (Lower leg)	0.490	0.510	0.000
L08 Other local infections of skin and subcutaneous tissue	0.489	0.511	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.487	0.513	0.000
N70 Salpingitis and oophoritis	0.487	0.513	0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.486	0.514	0.000
Z12.9 Special screening examination for neoplasm, unspecified	0.485	0.515	0.000
Z12.8 Special screening examination for neoplasm of other sites	0.485	0.515	0.000
Z12.6 Special screening examination for neoplasm of bladder	0.485	0.515	0.000
Z12.5 Special screening examination for neoplasm of prostate	0.485	0.515	0.000
Z12.4 Special screening examination for neoplasm of cervix	0.485	0.515	0.000
Z12.3 Special screening examination for neoplasm of breast	0.485	0.515	0.000
Z12.2 Special screening examination for neoplasm of respiratory organs	0.485	0.515	0.000
Z12.0 Special screening examination for neoplasm of stomach	0.485	0.515	0.000
N97 Female infertility	0.485	0.515	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.483	0.517	0.000
Chapter XI Diseases of the digestive system	0.483	0.517	0.000
C60-C63 Malignant neoplasms of male genital organs	0.483	0.517	0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.482	0.518	0.000
N92.6 Irregular menstruation, unspecified	0.481	0.519	0.000
G61 Inflammatory polyneuropathy	0.480	0.519	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.480	0.519	0.000
N81.3 Complete uterovaginal prolapse	0.479	0.521	0.000
N83.1 Corpus luteum cyst	0.478	0.522	0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.478	0.522	0.000
C64-C68 Malignant neoplasms of urinary tract	0.477	0.523	0.000
Z13.8 Special screening examination for other specified diseases and disorders	0.477	0.523	0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities	0.477	0.523	0.000
Z13.5 Special screening examination for eye and ear disorders	0.477	0.523	0.000
Z13.4 Special screening examination for certain developmental disorders in childhood	0.477	0.523	0.000
Z13.3 Special screening examination for mental and behavioural disorders	0.477	0.523	0.000
Z13.2 Special screening examination for nutritional disorders	0.477	0.523	0.000
B99-B99 Other infectious diseases	0.477	0.523	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.477	0.523	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.477	0.523	0.000
B65-B83 Helminthiases	0.477	0.523	0.000
B50-B64 Protozoal diseases	0.477	0.523	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.477	0.523	0.000
B15-B19 Viral hepatitis	0.477	0.523	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.477	0.523	0.000
A80-A89 Viral infections of the central nervous system	0.477	0.523	0.000
A75-A79 Rickettsioses	0.477	0.523	0.000
A70-A74 Other diseases caused by chlamydiae	0.477	0.523	0.000
A65-A69 Other spirochaetal diseases	0.477	0.523	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.477	0.523	0.000
A20-A28 Certain zoonotic bacterial diseases	0.477	0.523	0.000
A15-A19 Tuberculosis	0.477	0.523	0.000
L03.8 Cellulitis of other sites	0.476	0.523	0.000
L03.2 Cellulitis of face	0.476	0.523	0.000
L03.0 Cellulitis of finger and toe	0.476	0.523	0.000
S80-S89 Injuries to the knee and lower leg	0.476	0.524	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.476	0.524	0.000
Z30 Contraceptive management	0.475	0.525	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.474	0.526	0.000
T79-T79 Certain early complications of trauma	0.474	0.526	0.000
T66-T78 Other and unspecified effects of external causes	0.474	0.526	0.000
T33-T35 Frostbite	0.474	0.526	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.474	0.526	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.474	0.526	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.474	0.526	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.474	0.526	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.474	0.526	0.000
T00-T07 Injuries involving multiple body regions	0.474	0.526	0.000
S90-S99 Injuries to the ankle and foot	0.474	0.526	0.000
S20-S29 Injuries to the thorax	0.474	0.526	0.000
S10-S19 Injuries to the neck	0.474	0.526	0.000
G57.6 Lesion of plantar nerve	0.473	0.527	0.000
Z96.6 Presence of orthopaedic joint implants	0.472	0.528	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.471	0.529	0.000
Z96.8 Presence of other specified functional implants	0.468	0.532	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.468	0.532	0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.467	0.533	0.000
Z02.8 Other examinations for administrative purposes	0.467	0.533	0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle	0.467	0.533	0.000
N94.5 Secondary dysmenorrhoea	0.467	0.533	0.000
N94.4 Primary dysmenorrhoea	0.467	0.533	0.000
N94.3 Premenstrual tension syndrome	0.467	0.533	0.000
N94.2 Vaginismus	0.467	0.533	0.000
N94.0 Mittelschmerz	0.467	0.533	0.000
O42 Premature rupture of membranes	0.467	0.533	0.000
Z93 Artificial opening status	0.466	0.534	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.466	0.534	0.000
Z97 Presence of other devices	0.466	0.534	0.000
Z94 Transplanted organ and tissue status	0.466	0.534	0.000
Z89 Acquired absence of limb	0.466	0.534	0.000
Z84 Family history of other conditions	0.466	0.534	0.000
Z81 Family history of mental and behavioural disorders	0.466	0.534	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.463	0.537	0.000
O85-O92 Complications predominantly related to the puerperium	0.462	0.538	0.000
G51.0 Bell's palsy	0.462	0.538	0.000
S50-S59 Injuries to the elbow and forearm	0.462	0.538	0.000
Z80.4 Family history of malignant neoplasm of genital organs	0.462	0.538	0.000
D36 Benign neoplasm of other and unspecified sites	0.462	0.538	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.462	0.538	0.000
D32 Benign neoplasm of meninges	0.462	0.538	0.000
D31 Benign neoplasm of eye and adnexa	0.462	0.538	0.000
D30 Benign neoplasm of urinary organs	0.462	0.538	0.000
D29 Benign neoplasm of male genital organs	0.462	0.538	0.000
D28 Benign neoplasm of other and unspecified female genital organs	0.462	0.538	0.000
D26 Other benign neoplasms of uterus	0.462	0.538	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.462	0.538	0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.462	0.538	0.000
D19 Benign neoplasm of mesothelial tissue	0.462	0.538	0.000
D16 Benign neoplasm of bone and articular cartilage	0.462	0.538	0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.462	0.538	0.000
D14 Benign neoplasm of middle ear and respiratory system	0.462	0.538	0.000
D11 Benign neoplasm of major salivary glands	0.462	0.538	0.000
D10 Benign neoplasm of mouth and pharynx	0.462	0.538	0.000
D34 Benign neoplasm of thyroid gland	0.462	0.538	0.000
N92.5 Other specified irregular menstruation	0.461	0.539	0.000
N92.4 Excessive bleeding in the premenopausal period	0.461	0.539	0.000
N92.2 Excessive menstruation at puberty	0.461	0.539	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.459	0.541	0.000
G58 Other mononeuropathies	0.459	0.541	0.000
G54 Nerve root and plexus disorders	0.459	0.541	0.000
G53 Cranial nerve disorders in diseases classified elsewhere	0.459	0.541	0.000
G52 Disorders of other cranial nerves	0.459	0.541	0.000
M67 Other disorders of synovium and tendon	0.459	0.541	0.000
M87 Osteonecrosis	0.457	0.542	0.000
M20-M25 Other joint disorders	0.457	0.543	0.000
Z98.1 Arthrodesis status	0.456	0.544	0.000
J47 Bronchiectasis	0.456	0.544	0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.456	0.544	0.000
D00-D09 In situ neoplasms	0.454	0.546	0.000
J95-J99 Other diseases of the respiratory system	0.454	0.546	0.000
B35-B49 Mycoses	0.454	0.546	0.000
M85 Other disorders of bone density and structure	0.453	0.546	0.000
M84 Disorders of continuity of bone	0.453	0.546	0.000
M83 Adult osteomalacia	0.453	0.546	0.000
M82 Osteoporosis in diseases classified elsewhere	0.453	0.546	0.000
M80 Osteoporosis with pathological fracture	0.453	0.546	0.000
Z80.9 Family history of malignant neoplasm, unspecified	0.452	0.547	0.000
Z80.8 Family history of malignant neoplasm of other organs or systems	0.452	0.547	0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.452	0.547	0.000
Z80.6 Family history of leukaemia	0.452	0.547	0.000
Z80.5 Family history of malignant neoplasm of urinary tract	0.452	0.547	0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.452	0.547	0.000
A41 Other septicaemia	0.451	0.549	0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.450	0.549	0.000
N76 Other inflammation of vagina and vulva	0.450	0.549	0.000
N75 Diseases of Bartholin's gland	0.450	0.549	0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.450	0.549	0.000
N71 Inflammatory disease of uterus, except cervix	0.450	0.549	0.000
B02 Zoster [herpes zoster]	0.450	0.550	0.000
S40-S49 Injuries to the shoulder and upper arm	0.449	0.550	0.000
Z33 Pregnant state, incidental	0.449	0.551	0.000
Chapter XX External causes of morbidity and mortality	0.449	0.551	0.000
G56 Mononeuropathies of upper limb	0.449	0.551	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.449	0.551	0.000
N94.6 Dysmenorrhoea, unspecified	0.449	0.551	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.448	0.552	0.000
M10.99 Gout, unspecified (Site unspecified)	0.448	0.552	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.447	0.553	0.000
Z34 Supervision of normal pregnancy	0.447	0.553	0.000
Z35 Supervision of high-risk pregnancy	0.447	0.553	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.446	0.554	0.000
A00-A09 Intestinal infectious diseases	0.446	0.554	0.000
N17-N19 Renal failure	0.446	0.554	0.000
Z83.5 Family history of eye and ear disorders	0.445	0.555	0.000
B25-B34 Other viral diseases	0.445	0.555	0.000
N61 Inflammatory disorders of breast	0.444	0.556	0.000
N81.9 Female genital prolapse, unspecified	0.443	0.556	0.000
N81.8 Other female genital prolapse	0.443	0.556	0.000
N81.0 Female urethrocele	0.443	0.556	0.000
D24 Benign neoplasm of breast	0.443	0.557	0.000
C51-C58 Malignant neoplasms of female genital organs	0.443	0.557	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.442	0.558	0.000
D12.4 Descending colon	0.442	0.558	0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.441	0.558	0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.441	0.558	0.000
N83.7 Haematoma of broad ligament	0.441	0.558	0.000
N83.6 Haematosalpinx	0.441	0.558	0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube	0.441	0.558	0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube	0.441	0.558	0.000
N83.3 Acquired atrophy of ovary and Fallopian tube	0.441	0.558	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.441	0.559	0.000
L43 Lichen planus	0.440	0.559	0.000
G35 Multiple sclerosis	0.440	0.560	0.000
D12.9 Anus and anal canal	0.440	0.560	0.000
D12.1 Appendix	0.440	0.560	0.000
E00-E07 Disorders of thyroid gland	0.439	0.561	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.438	0.562	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.438	0.562	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.437	0.563	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.437	0.563	0.000
D46 Myelodysplastic syndromes	0.437	0.563	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.437	0.563	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.437	0.563	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.437	0.563	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.437	0.563	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.437	0.563	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.437	0.563	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.437	0.563	0.000
N90.5 Atrophy of vulva	0.436	0.564	0.000
G50.0 Trigeminal neuralgia	0.436	0.564	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.436	0.564	0.000
J60-J70 Lung diseases due to external agents	0.436	0.564	0.000
C91 Lymphoid leukaemia	0.435	0.565	0.000
N86 Erosion and ectropion of cervix uteri	0.435	0.565	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.432	0.568	0.000
O36 Maternal care for other known or suspected foetal problems	0.432	0.568	0.000
N03 Chronic nephritic syndrome	0.431	0.569	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.431	0.569	0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.430	0.570	0.000
C73 Malignant neoplasm of thyroid gland	0.430	0.570	0.000
M70-M79 Other soft tissue disorders	0.429	0.571	0.000
M10.4 Other secondary gout	0.429	0.571	0.000
M10.3 Gout due to impairment of renal function	0.429	0.571	0.000
M10.2 Drug-induced gout	0.429	0.571	0.000
M10.1 Lead-induced gout	0.429	0.571	0.000
M10.0 Idiopathic gout	0.429	0.571	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.428	0.571	0.000
N95.9 Menopausal and perimenopausal disorder, unspecified	0.428	0.572	0.000
N95.8 Other specified menopausal and perimenopausal disorders	0.428	0.572	0.000
N95.3 States associated with artificial menopause	0.428	0.572	0.000
N95.1 Menopausal and female climacteric states	0.428	0.572	0.000
N85.9 Noninflammatory disorder of uterus, unspecified	0.428	0.572	0.000
G25 Other extrapyramidal and movement disorders	0.427	0.573	0.000
G24 Dystonia	0.427	0.573	0.000
G23 Other degenerative diseases of basal ganglia	0.427	0.573	0.000
G21 Secondary Parkinsonism	0.427	0.573	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.427	0.573	0.000
G22 Parkinsonism in diseases classified elsewhere	0.427	0.573	0.000
C25 Malignant neoplasm of pancreas	0.427	0.573	0.000
Z39 Postpartum care and examination	0.427	0.573	0.000
Z38 Liveborn infants according to place of birth	0.427	0.573	0.000
Z36 Antenatal screening	0.427	0.573	0.000
Z32 Pregnancy examination and test	0.427	0.573	0.000
Z31 Procreative management	0.427	0.573	0.000
O47 False labour	0.427	0.573	0.000
S32 Fracture of lumbar spine and pelvis	0.426	0.574	0.000
J43 Emphysema	0.424	0.576	0.000
N23 Unspecified renal colic	0.422	0.578	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.422	0.578	0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.422	0.578	0.000
L95 Vasculitis limited to skin, not elsewhere classified	0.422	0.578	0.000
L94 Other localised connective tissue disorders	0.422	0.578	0.000
L93 Lupus erythematosus	0.422	0.578	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.422	0.578	0.000
L89 Decubitus ulcer	0.422	0.578	0.000
L87 Transepidermal elimination disorders	0.422	0.578	0.000
L85 Other epidermal thickening	0.422	0.578	0.000
L81 Other disorders of pigmentation	0.422	0.578	0.000
L88 Pyoderma gangrenosum	0.422	0.578	0.000
L86 Keratoderma in diseases classified elsewhere	0.422	0.578	0.000
L84 Corns and callosities	0.422	0.578	0.000
L83 Acanthosis nigricans	0.422	0.578	0.000
L80 Vitiligo	0.422	0.578	0.000
H65-H75 Diseases of middle ear and mastoid	0.421	0.579	0.000
N85.2 Hypertrophy of uterus	0.421	0.579	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.420	0.579	0.000
C95 Leukaemia of unspecified cell type	0.420	0.579	0.000
C94 Other leukaemias of specified cell type	0.420	0.579	0.000
C93 Monocytic leukaemia	0.420	0.579	0.000
C92 Myeloid leukaemia	0.420	0.579	0.000
C88 Malignant immunoproliferative diseases	0.420	0.579	0.000
C86 Other specified types of T/NK-cell lymphoma	0.420	0.579	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.420	0.579	0.000
C81 Hodgkin's disease	0.420	0.579	0.000
Z83.6 Family history of diseases of the respiratory system	0.420	0.580	0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.420	0.580	0.000
Z83.3 Family history of diabetes mellitus	0.420	0.580	0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.420	0.580	0.000
Z83.1 Family history of other infectious and parasitic diseases	0.420	0.580	0.000
Z83.0 Family history of human immunodeficiency virus [HIV]	0.420	0.580	0.000
J00-J06 Acute upper respiratory infections	0.419	0.581	0.000
N83.2 Other and unspecified ovarian cysts	0.419	0.581	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.419	0.581	0.000
D12.6 Colon, unspecified	0.418	0.581	0.000
J20-J22 Other acute lower respiratory infections	0.418	0.582	0.000
Z87.4 Personal history of diseases of the genito-urinary system	0.418	0.582	0.000
G43 Migraine	0.417	0.583	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.415	0.584	0.000
Z57 Occupational exposure to risk-factors	0.415	0.585	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.415	0.585	0.000
S64 Injury of nerves at wrist and hand level	0.414	0.585	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.414	0.586	0.000
L05.9 Pilonidal cyst without abscess	0.413	0.586	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.413	0.587	0.000
G60 Hereditary and idiopathic neuropathy	0.413	0.587	0.000
G64 Other disorders of peripheral nervous system	0.413	0.587	0.000
Chapter V Mental and behavioural disorders	0.413	0.587	0.001
M65 Synovitis and tenosynovitis	0.413	0.587	0.000
Z90.1 Acquired absence of breast(s)	0.413	0.587	0.000
D22 Melanocytic naevi	0.412	0.588	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.412	0.588	0.000
M66 Spontaneous rupture of synovium and tendon	0.412	0.588	0.000
G61.0 Guillain-Barre syndrome	0.412	0.588	0.000
D18 Haemangioma and lymphangioma, any site	0.412	0.588	0.000
M90 Osteopathies in diseases classified elsewhere	0.411	0.589	0.000
M89 Other disorders of bone	0.411	0.589	0.000
M88 Paget's disease of bone [osteitis deformans]	0.411	0.589	0.000
M86 Osteomyelitis	0.411	0.589	0.000
H90-H95 Other disorders of ear	0.411	0.589	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.411	0.589	0.000
S00 Superficial injury of head	0.411	0.589	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.411	0.589	0.000
J41 Simple and mucopurulent chronic bronchitis	0.410	0.590	0.000
J46 Status asthmaticus	0.410	0.590	0.000
J42 Unspecified chronic bronchitis	0.410	0.590	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.410	0.590	0.000
O00-O08 Pregnancy with abortive outcome	0.410	0.590	0.000
Z98.8 Other specified postsurgical states	0.410	0.590	0.000
Z98.2 Presence of cerebrospinal fluid drainage device	0.410	0.590	0.000
D23 Other benign neoplasms of skin	0.410	0.590	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.409	0.591	0.000
J40 Bronchitis, not specified as acute or chronic	0.409	0.591	0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.409	0.591	0.000
D12.3 Transverse colon	0.408	0.591	0.000
M06.9 Rheumatoid arthritis, unspecified	0.408	0.592	0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.408	0.592	0.000
Z02.9 Examination for administrative purposes, unspecified	0.408	0.592	0.000
Z02.7 Issue of medical certificate	0.408	0.592	0.000
Z02.6 Examination for insurance purposes	0.408	0.592	0.000
Z02.5 Examination for participation in sport	0.408	0.592	0.000
Z02.4 Examination for driving licence	0.408	0.592	0.000
Z02.3 Examination for recruitment to armed forces	0.408	0.592	0.000
Z02.2 Examination for admission to residential institution	0.408	0.592	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations