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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs139052640
log Bayes Factor = 3.08938
Chromosome 1   position 212,728,370  (GRCh37) Explore rs139052640 on Ensembl!
Variant rs139052640 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.999 0.001 0.000
Chapter II Neoplasms
0.992 0.008 0.000
R30-R39 Symptoms and signs involving the urinary system
0.987 0.013 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.987 0.013 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.979 0.021 0.000
Chapter X Diseases of the respiratory system
0.968 0.032 0.000
D10-D36 Benign neoplasms
0.968 0.032 0.000
R39 Other symptoms and signs involving the urinary system
0.958 0.042 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.953 0.047 0.000
J20-J22 Other acute lower respiratory infections
0.947 0.053 0.000
Chapter VIII Diseases of the ear and mastoid process
0.940 0.060 0.000
J22 Unspecified acute lower respiratory infection
0.933 0.067 0.000
M50-M54 Other dorsopathies
0.925 0.075 0.000
R33 Retention of urine
0.924 0.076 0.000
Chapter IX Diseases of the circulatory system
0.923 0.077 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.922 0.078 0.000
R39.1 Other difficulties with micturition
0.913 0.087 0.000
R32 Unspecified urinary incontinence
0.911 0.089 0.000
D25 Leiomyoma of uterus
0.910 0.090 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.905 0.095 0.000
I30-I52 Other forms of heart disease
0.895 0.105 0.000
H65-H75 Diseases of middle ear and mastoid
0.877 0.123 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.874 0.126 0.000
M70-M79 Other soft tissue disorders
0.874 0.126 0.000
Chapter XIV Diseases of the genitourinary system
0.871 0.129 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.865 0.135 0.000
R35 Polyuria
0.859 0.141 0.000
N30-N39 Other diseases of urinary system
0.859 0.141 0.000
Chapter V Mental and behavioural disorders
0.856 0.144 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.855 0.145 0.000
I50 Heart failure
0.855 0.145 0.000
M54 Dorsalgia
0.855 0.145 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.851 0.149 0.000
D23 Other benign neoplasms of skin
0.849 0.150 0.000
R31 Unspecified haematuria
0.839 0.161 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.835 0.165 0.000
S60-S69 Injuries to the wrist and hand
0.821 0.179 0.000
D24 Benign neoplasm of breast
0.815 0.185 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.811 0.188 0.000
M20-M25 Other joint disorders
0.810 0.190 0.000
D25.0 Submucous leiomyoma of uterus
0.810 0.190 0.000
N32 Other disorders of bladder
0.808 0.192 0.000
N39 Other disorders of urinary system
0.808 0.192 0.000
J30-J39 Other diseases of upper respiratory tract
0.806 0.194 0.000
C43 Malignant melanoma of skin
0.805 0.195 0.000
D27 Benign neoplasm of ovary
0.800 0.199 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.800 0.200 0.000
D25.9 Leiomyoma of uterus, unspecified
0.797 0.203 0.000
R50-R69 General symptoms and signs
0.777 0.223 0.000
I50.1 Left ventricular failure
0.775 0.225 0.000
H90-H95 Other disorders of ear
0.774 0.225 0.000
N39.4 Other specified urinary incontinence
0.771 0.229 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.766 0.234 0.000
S50-S59 Injuries to the elbow and forearm
0.761 0.239 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.759 0.241 0.000
C34 Malignant neoplasm of bronchus and lung
0.757 0.243 0.000
D22 Melanocytic naevi
0.756 0.244 0.000
H66 Suppurative and unspecified otitis media
0.753 0.247 0.000
H72 Perforation of tympanic membrane
0.752 0.248 0.000
I35 Nonrheumatic aortic valve disorders
0.751 0.249 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.749 0.251 0.000
C51-C58 Malignant neoplasms of female genital organs
0.747 0.253 0.000
M05-M14 Inflammatory polyarthropathies
0.745 0.254 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.745 0.255 0.000
C44 Other malignant neoplasms of skin
0.745 0.255 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.744 0.256 0.000
S80-S89 Injuries to the knee and lower leg
0.744 0.256 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.741 0.259 0.000
O80-O84 Delivery
0.740 0.260 0.000
I50.9 Heart failure, unspecified
0.736 0.263 0.000
O47 False labour
0.736 0.264 0.000
N40-N51 Diseases of male genital organs
0.735 0.265 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.735 0.265 0.000
O60-O75 Complications of labour and delivery
0.735 0.265 0.000
I05-I09 Chronic rheumatic heart diseases
0.732 0.268 0.000
M50 Cervical disk disorders
0.732 0.268 0.000
I60-I69 Cerebrovascular diseases
0.731 0.269 0.000
M51 Other intervertebral disk disorders
0.731 0.269 0.000
D11 Benign neoplasm of major salivary glands
0.730 0.270 0.000
M75 Shoulder lesions
0.729 0.271 0.000
S61 Open wound of wrist and hand
0.725 0.275 0.000
I47 Paroxysmal tachycardia
0.724 0.276 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.722 0.278 0.000
J60-J70 Lung diseases due to external agents
0.721 0.279 0.000
C64-C68 Malignant neoplasms of urinary tract
0.717 0.283 0.000
I31 Other diseases of pericardium
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.716 0.284 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.716 0.284 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.716 0.284 0.000
I44 Atrioventricular and left bundle-branch block
0.714 0.286 0.000
S00-S09 Injuries to the head
0.713 0.287 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.713 0.287 0.000
M80-M85 Disorders of bone density and structure
0.712 0.288 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.711 0.289 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.711 0.289 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.711 0.289 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.711 0.289 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.711 0.289 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.711 0.289 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.710 0.290 0.000
R36 Urethral discharge
0.708 0.292 0.000
R34 Anuria and oliguria
0.708 0.292 0.000
R59 Enlarged lymph nodes
0.708 0.292 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.708 0.292 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.708 0.292 0.000
M54.9 Dorsalgia, unspecified
0.707 0.293 0.000
N32.8 Other specified disorders of bladder
0.705 0.295 0.000
D17 Benign lipomatous neoplasm
0.704 0.295 0.000
M20 Acquired deformities of fingers and toes
0.704 0.296 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.702 0.298 0.000
M91-M94 Chondropathies
0.702 0.298 0.000
M86-M90 Other osteopathies
0.702 0.298 0.000
M60-M63 Disorders of muscles
0.702 0.298 0.000
M00-M03 Infectious arthropathies
0.702 0.298 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.696 0.304 0.000
C79 Secondary malignant neoplasm of other sites
0.695 0.305 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.694 0.306 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.694 0.306 0.000
D36 Benign neoplasm of other and unspecified sites
0.694 0.306 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.694 0.306 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.694 0.306 0.000
D32 Benign neoplasm of meninges
0.694 0.306 0.000
D31 Benign neoplasm of eye and adnexa
0.694 0.306 0.000
D30 Benign neoplasm of urinary organs
0.694 0.306 0.000
D29 Benign neoplasm of male genital organs
0.694 0.306 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.694 0.306 0.000
D26 Other benign neoplasms of uterus
0.694 0.306 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.694 0.306 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.694 0.306 0.000
D19 Benign neoplasm of mesothelial tissue
0.694 0.306 0.000
D16 Benign neoplasm of bone and articular cartilage
0.694 0.306 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.694 0.306 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.694 0.306 0.000
D10 Benign neoplasm of mouth and pharynx
0.694 0.306 0.000
D34 Benign neoplasm of thyroid gland
0.694 0.306 0.000
M45-M49 Spondylopathies
0.693 0.307 0.000
M54.5 Low back pain
0.692 0.308 0.000
D18 Haemangioma and lymphangioma, any site
0.690 0.309 0.000
D23.5 Skin of trunk
0.688 0.312 0.000
J00-J06 Acute upper respiratory infections
0.687 0.313 0.000
R39.2 Extrarenal uraemia
0.687 0.313 0.000
R39.0 Extravasation of urine
0.687 0.313 0.000
M54.2 Cervicalgia
0.686 0.314 0.000
F99-F99 Unspecified mental disorder
0.685 0.315 0.000
J95-J99 Other diseases of the respiratory system
0.685 0.315 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.684 0.316 0.000
D25.2 Subserosal leiomyoma of uterus
0.684 0.316 0.000
O85-O92 Complications predominantly related to the puerperium
0.683 0.317 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.683 0.317 0.000
M77 Other enthesopathies
0.681 0.318 0.000
M40-M43 Deforming dorsopathies
0.681 0.319 0.000
N32.3 Diverticulum of bladder
0.681 0.319 0.000
Chapter I Certain infectious and parasitic diseases
0.680 0.320 0.000
J81 Pulmonary oedema
0.680 0.320 0.000
J21 Acute bronchiolitis
0.679 0.321 0.000
J20 Acute bronchitis
0.679 0.321 0.000
N36 Other disorders of urethra
0.679 0.321 0.000
I50.0 Congestive heart failure
0.679 0.321 0.000
M54.3 Sciatica
0.679 0.321 0.000
H65 Nonsuppurative otitis media
0.677 0.323 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.677 0.323 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.676 0.323 0.000
M65-M68 Disorders of synovium and tendon
0.675 0.325 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.674 0.326 0.000
O48 Prolonged pregnancy
0.674 0.326 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.674 0.326 0.000
H60-H62 Diseases of external ear
0.674 0.326 0.000
D00-D09 In situ neoplasms
0.674 0.326 0.000
S20-S29 Injuries to the thorax
0.672 0.328 0.000
M15-M19 Arthrosis
0.670 0.330 0.000
R47-R49 Symptoms and signs involving speech and voice
0.670 0.330 0.000
M79.6 Pain in limb
0.670 0.330 0.000
S40-S49 Injuries to the shoulder and upper arm
0.669 0.331 0.000
C44.3 Skin of other and unspecified parts of face
0.669 0.331 0.000
R30 Pain associated with micturition
0.666 0.334 0.000
M53 Other dorsopathies, not elsewhere classified
0.663 0.336 0.000
H66.9 Otitis media, unspecified
0.663 0.337 0.000
D23.7 Skin of lower limb, including hip
0.662 0.338 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.662 0.338 0.000
I00-I02 Acute rheumatic fever
0.662 0.338 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.661 0.339 0.000
T79-T79 Certain early complications of trauma
0.661 0.339 0.000
T66-T78 Other and unspecified effects of external causes
0.661 0.339 0.000
T33-T35 Frostbite
0.661 0.339 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.661 0.339 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.661 0.339 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.661 0.339 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.661 0.339 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.661 0.339 0.000
T00-T07 Injuries involving multiple body regions
0.661 0.339 0.000
S90-S99 Injuries to the ankle and foot
0.661 0.339 0.000
S10-S19 Injuries to the neck
0.661 0.339 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.661 0.339 0.000
D22.5 Melanocytic naevi of trunk
0.661 0.339 0.000
D23.3 Skin of other and unspecified parts of face
0.661 0.339 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.660 0.340 0.000
L60-L75 Disorders of skin appendages
0.659 0.341 0.000
H71 Cholesteatoma of middle ear
0.658 0.342 0.000
F17.2 Dependence syndrome
0.657 0.343 0.000
J36 Peritonsillar abscess
0.657 0.343 0.000
C34.9 Bronchus or lung, unspecified
0.657 0.343 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.657 0.343 0.000
H90 Conductive and sensorineural hearing loss
0.655 0.345 0.000
R79 Other abnormal findings of blood chemistry
0.654 0.346 0.000
M24 Other specific joint derangements
0.653 0.346 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.652 0.347 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.651 0.348 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.651 0.349 0.000
O36 Maternal care for other known or suspected foetal problems
0.649 0.351 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.649 0.351 0.000
H80-H83 Diseases of inner ear
0.648 0.352 0.000
J09-J18 Influenza and pneumonia
0.646 0.354 0.000
S52 Fracture of forearm
0.646 0.354 0.000
I49 Other cardiac arrhythmias
0.645 0.355 0.000
N32.0 Bladder-neck obstruction
0.644 0.356 0.000
D23.1 Skin of eyelid, including canthus
0.644 0.356 0.000
N99-N99 Other disorders of the genitourinary system
0.644 0.356 0.000
I20-I25 Ischaemic heart diseases
0.643 0.357 0.000
I52 Other heart disorders in diseases classified elsewhere
0.641 0.358 0.000
I48 Atrial fibrillation and flutter
0.641 0.358 0.000
I46 Cardiac arrest
0.641 0.358 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.641 0.358 0.000
I41 Myocarditis in diseases classified elsewhere
0.641 0.358 0.000
I40 Acute myocarditis
0.641 0.358 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.641 0.358 0.000
I37 Pulmonary valve disorders
0.641 0.358 0.000
I36 Nonrheumatic tricuspid valve disorders
0.641 0.358 0.000
I33 Acute and subacute endocarditis
0.641 0.358 0.000
I32 Pericarditis in diseases classified elsewhere
0.641 0.358 0.000
I30 Acute pericarditis
0.641 0.358 0.000
I38 Endocarditis, valve unspecified
0.641 0.358 0.000
S70-S79 Injuries to the hip and thigh
0.640 0.359 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.638 0.361 0.000
C77.3 Axillary and upper limb lymph nodes
0.638 0.362 0.000
S64 Injury of nerves at wrist and hand level
0.638 0.362 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.636 0.364 0.000
O32.1 Maternal care for breech presentation
0.636 0.364 0.000
R53 Malaise and fatigue
0.635 0.365 0.000
R59.0 Localised enlarged lymph nodes
0.632 0.368 0.000
L20-L30 Dermatitis and eczema
0.631 0.369 0.000
D25.1 Intramural leiomyoma of uterus
0.630 0.369 0.000
O42 Premature rupture of membranes
0.630 0.370 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.629 0.371 0.000
H74 Other disorders of middle ear and mastoid
0.629 0.371 0.000
H73 Other disorders of tympanic membrane
0.629 0.371 0.000
H70 Mastoiditis and related conditions
0.629 0.371 0.000
H69 Other disorders of Eustachian tube
0.629 0.371 0.000
H68 Eustachian salpingitis and obstruction
0.629 0.371 0.000
H67 Otitis media in diseases classified elsewhere
0.629 0.371 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.629 0.371 0.000
R73 Elevated blood glucose level
0.628 0.372 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.626 0.373 0.000
O45 Premature separation of placenta [abruptio placentae]
0.626 0.373 0.000
O44 Placenta praevia
0.626 0.373 0.000
O43 Placental disorders
0.626 0.373 0.000
O41 Other disorders of amniotic fluid and membranes
0.626 0.373 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.626 0.373 0.000
O33 Maternal care for known or suspected disproportion
0.626 0.373 0.000
O31 Complications specific to multiple gestation
0.626 0.373 0.000
O30 Multiple gestation
0.626 0.373 0.000
O40 Polyhydramnios
0.626 0.373 0.000
M76 Enthesopathies of lower limb, excluding foot
0.626 0.374 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.626 0.374 0.000
M71 Other bursopathies
0.626 0.374 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.626 0.374 0.000
O00-O08 Pregnancy with abortive outcome
0.623 0.377 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.623 0.377 0.000
I42 Cardiomyopathy
0.622 0.378 0.000
C15-C26 Malignant neoplasms of digestive organs
0.621 0.379 0.000
C80 Malignant neoplasm without specification of site
0.620 0.379 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.620 0.379 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.620 0.380 0.000
I44.0 Atrioventricular block, first degree
0.619 0.381 0.000
J90-J94 Other diseases of pleura
0.619 0.381 0.000
J34 Other disorders of nose and nasal sinuses
0.619 0.381 0.000
H72.0 Central perforation of tympanic membrane
0.618 0.381 0.000
R60 Oedema, not elsewhere classified
0.618 0.382 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.617 0.383 0.000
N37 Urethral disorders in diseases classified elsewhere
0.616 0.384 0.000
N34 Urethritis and urethral syndrome
0.616 0.384 0.000
N33 Bladder disorders in diseases classified elsewhere
0.616 0.384 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.614 0.386 0.000
F80-F89 Disorders of psychological development
0.614 0.386 0.000
F70-F79 Mental retardation
0.614 0.386 0.000
F60-F69 Disorders of adult personality and behaviour
0.614 0.386 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.614 0.386 0.000
N39.0 Urinary tract infection, site not specified
0.614 0.386 0.000
N00-N08 Glomerular diseases
0.613 0.387 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.613 0.387 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.613 0.387 0.000
C32 Malignant neoplasm of larynx
0.613 0.387 0.000
C31 Malignant neoplasm of accessory sinuses
0.613 0.387 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.613 0.387 0.000
C37 Malignant neoplasm of thymus
0.613 0.387 0.000
C33 Malignant neoplasm of trachea
0.613 0.387 0.000
M54.8 Other dorsalgia
0.613 0.387 0.000
M54.6 Pain in thoracic spine
0.613 0.387 0.000
M54.4 Lumbago with sciatica
0.613 0.387 0.000
M54.1 Radiculopathy
0.613 0.387 0.000
M54.0 Panniculitis affecting regions of neck and back
0.613 0.387 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.613 0.387 0.000
O47.9 False labour, unspecified
0.613 0.387 0.000
L50-L54 Urticaria and erythema
0.610 0.389 0.000
L10-L14 Bullous disorders
0.610 0.389 0.000
N32.9 Bladder disorder, unspecified
0.609 0.391 0.000
D23.9 Skin, unspecified
0.609 0.391 0.000
D23.6 Skin of upper limb, including shoulder
0.609 0.391 0.000
D23.4 Skin of scalp and neck
0.609 0.391 0.000
D23.2 Skin of ear and external auricular canal
0.609 0.391 0.000
D23.0 Skin of lip
0.609 0.391 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.609 0.391 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.608 0.392 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.606 0.394 0.000
S01 Open wound of head
0.606 0.394 0.000
C34.3 Lower lobe, bronchus or lung
0.605 0.395 0.000
I47.1 Supraventricular tachycardia
0.605 0.395 0.000
R54 Senility
0.604 0.396 0.000
M20.0 Deformity of finger(s)
0.601 0.399 0.000
N60-N64 Disorders of breast
0.601 0.399 0.000
L40-L45 Papulosquamous disorders
0.601 0.399 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.596 0.403 0.000
S62 Fracture at wrist and hand level
0.596 0.404 0.000
I08 Multiple valve diseases
0.596 0.404 0.000
S61.0 Open wound of finger(s) without damage to nail
0.596 0.404 0.000
S82 Fracture of lower leg, including ankle
0.595 0.404 0.000
N25-N29 Other disorders of kidney and ureter
0.594 0.406 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.593 0.407 0.000
J39 Other diseases of upper respiratory tract
0.592 0.408 0.000
C77.9 Lymph node, unspecified
0.592 0.408 0.000
M51.2 Other specified intervertebral disk displacement
0.591 0.409 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.590 0.410 0.000
I35.0 Aortic (valve) stenosis
0.590 0.410 0.000
I31.3 Pericardial effusion (noninflammatory)
0.589 0.410 0.000
L82 Seborrhoeic keratosis
0.589 0.411 0.000
D45 Polycythaemia vera
0.589 0.411 0.000
M75.1 Rotator cuff syndrome
0.589 0.411 0.000
S69 Other and unspecified injuries of wrist and hand
0.588 0.412 0.000
S68 Traumatic amputation of wrist and hand
0.588 0.412 0.000
S67 Crushing injury of wrist and hand
0.588 0.412 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.588 0.412 0.000
S65 Injury of blood vessels at wrist and hand level
0.588 0.412 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.588 0.412 0.000
S60 Superficial injury of wrist and hand
0.588 0.412 0.000
L85 Other epidermal thickening
0.588 0.412 0.000
M05 Seropositive rheumatoid arthritis
0.587 0.413 0.000
O80 Single spontaneous delivery
0.586 0.413 0.000
M35 Other systemic involvement of connective tissue
0.585 0.415 0.000
C43.5 Malignant melanoma of trunk
0.584 0.416 0.000
I63 Cerebral infarction
0.582 0.418 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.582 0.418 0.000
R77 Other abnormalities of plasma proteins
0.582 0.418 0.000
R76 Other abnormal immunological findings in serum
0.582 0.418 0.000
R74 Abnormal serum enzyme levels
0.582 0.418 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.582 0.418 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.582 0.418 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.582 0.418 0.000
R71 Abnormality of red blood cells
0.582 0.418 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.581 0.419 0.000
M34 Systemic sclerosis
0.581 0.419 0.000
M33 Dermatopolymyositis
0.581 0.419 0.000
M32 Systemic lupus erythematosus
0.581 0.419 0.000
M31 Other necrotising vasculopathies
0.581 0.419 0.000
M30 Polyarteritis nodosa and related conditions
0.581 0.419 0.000
M22 Disorders of patella
0.581 0.419 0.000
M21 Other acquired deformities of limbs
0.581 0.419 0.000
M20.4 Other hammer toe(s) (acquired)
0.581 0.419 0.000
M54.57 Low back pain (Lumbosacral region)
0.581 0.419 0.000
I34 Nonrheumatic mitral valve disorders
0.580 0.420 0.000
S61.1 Open wound of finger(s) with damage to nail
0.580 0.420 0.000
N32.4 Rupture of bladder, nontraumatic
0.580 0.420 0.000
N32.2 Vesical fistula, not elsewhere classified
0.580 0.420 0.000
N32.1 Vesicointestinal fistula
0.580 0.420 0.000
I61 Intracerebral haemorrhage
0.579 0.421 0.000
N39.8 Other specified disorders of urinary system
0.579 0.421 0.000
N39.2 Orthostatic proteinuria, unspecified
0.579 0.421 0.000
N39.1 Persistent proteinuria, unspecified
0.579 0.421 0.000
J37 Chronic laryngitis and laryngotracheitis
0.578 0.422 0.000
J35 Chronic diseases of tonsils and adenoids
0.578 0.422 0.000
J30 Vasomotor and allergic rhinitis
0.578 0.422 0.000
R59.1 Generalised enlarged lymph nodes
0.577 0.423 0.000
C43.9 Malignant melanoma of skin, unspecified
0.577 0.423 0.000
C43.8 Overlapping malignant melanoma of skin
0.577 0.423 0.000
C43.4 Malignant melanoma of scalp and neck
0.577 0.423 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.577 0.423 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.577 0.423 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.577 0.423 0.000
C43.0 Malignant melanoma of lip
0.577 0.423 0.000
L91 Hypertrophic disorders of skin
0.576 0.424 0.000
J84 Other interstitial pulmonary diseases
0.574 0.426 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.574 0.426 0.000
J80 Adult respiratory distress syndrome
0.574 0.426 0.000
M79.66 Pain in limb (Lower leg)
0.572 0.428 0.000
M19 Other arthrosis
0.572 0.428 0.000
I60 Subarachnoid haemorrhage
0.571 0.429 0.000
N30 Cystitis
0.571 0.429 0.000
H90.2 Conductive hearing loss, unspecified
0.570 0.430 0.000
N45 Orchitis and epididymitis
0.570 0.430 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.569 0.431 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.569 0.431 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.567 0.433 0.000
N39.9 Disorder of urinary system, unspecified
0.567 0.433 0.000
C54 Malignant neoplasm of corpus uteri
0.567 0.433 0.000
R56 Convulsions, not elsewhere classified
0.566 0.434 0.000
M54.22 Cervicalgia (Cervical region)
0.565 0.435 0.000
O63 Long labour
0.565 0.435 0.000
M84 Disorders of continuity of bone
0.564 0.435 0.000
N42 Other disorders of prostate
0.564 0.436 0.000
M50.3 Other cervical disk degeneration
0.563 0.437 0.000
C50-C50 Malignant neoplasm of breast
0.563 0.437 0.000
S52.5 Fracture of lower end of radius
0.563 0.437 0.000
M72 Fibroblastic disorders
0.562 0.437 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.562 0.437 0.000
F99 Mental disorder, not otherwise specified
0.562 0.438 0.000
M50.0 Cervical disk disorder with myelopathy
0.562 0.438 0.000
N10-N16 Renal tubulo-interstitial diseases
0.562 0.438 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.561 0.439 0.000
D11.0 Parotid gland
0.559 0.440 0.000
N39.3 Stress incontinence
0.559 0.441 0.000
S32 Fracture of lumbar spine and pelvis
0.559 0.441 0.000
M10 Gout
0.559 0.441 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.558 0.442 0.000
R68 Other general symptoms and signs
0.557 0.443 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.557 0.443 0.000
R62 Lack of expected normal physiological development
0.557 0.443 0.000
R61 Hyperhidrosis
0.557 0.443 0.000
R57 Shock, not elsewhere classified
0.557 0.443 0.000
R52 Pain, not elsewhere classified
0.557 0.443 0.000
R64 Cachexia
0.557 0.443 0.000
R58 Haemorrhage, not elsewhere classified
0.557 0.443 0.000
L89 Decubitus ulcer
0.557 0.443 0.000
H91 Other hearing loss
0.557 0.443 0.000
M79.60 Pain in limb (Multiple sites)
0.556 0.443 0.000
C77.1 Intrathoracic lymph nodes
0.556 0.444 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.555 0.445 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.555 0.445 0.000
H93 Other disorders of ear, not elsewhere classified
0.555 0.445 0.000
H92 Otalgia and effusion of ear
0.555 0.445 0.000
N17-N19 Renal failure
0.555 0.445 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.555 0.445 0.000
M75.0 Adhesive capsulitis of shoulder
0.555 0.445 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.554 0.445 0.000
J32 Chronic sinusitis
0.554 0.446 0.000
O72 Postpartum haemorrhage
0.554 0.446 0.000
M13 Other arthritis
0.553 0.446 0.000
C44.1 Skin of eyelid, including canthus
0.553 0.447 0.000
I44.1 Atrioventricular block, second degree
0.553 0.447 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.553 0.447 0.000
M54.39 Sciatica (Site unspecified)
0.552 0.448 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.552 0.448 0.000
I35.1 Aortic (valve) insufficiency
0.552 0.448 0.000
C44.5 Skin of trunk
0.551 0.449 0.000
N36.8 Other specified disorders of urethra
0.551 0.449 0.000
S61.8 Open wound of other parts of wrist and hand
0.550 0.450 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.549 0.450 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.549 0.450 0.000
D46 Myelodysplastic syndromes
0.549 0.450 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.549 0.450 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.549 0.450 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.549 0.450 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.549 0.450 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.549 0.450 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.549 0.450 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.549 0.450 0.000
M23 Internal derangement of knee
0.549 0.451 0.000
F30-F39 Mood [affective] disorders
0.547 0.453 0.000
C77.0 Lymph nodes of head, face and neck
0.547 0.453 0.000
S59 Other and unspecified injuries of forearm
0.546 0.454 0.000
S58 Traumatic amputation of forearm
0.546 0.454 0.000
S57 Crushing injury of forearm
0.546 0.454 0.000
S56 Injury of muscle and tendon at forearm level
0.546 0.454 0.000
S55 Injury of blood vessels at forearm level
0.546 0.454 0.000
S54 Injury of nerves at forearm level
0.546 0.454 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.546 0.454 0.000
S51 Open wound of forearm
0.546 0.454 0.000
S50 Superficial injury of forearm
0.546 0.454 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.544 0.456 0.000
O97 Death from sequelae of direct obstetric causes
0.544 0.456 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.544 0.456 0.000
O95 Obstetric death of unspecified cause
0.544 0.456 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.544 0.456 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.544 0.456 0.000
M77.1 Lateral epicondylitis
0.544 0.456 0.000
J69 Pneumonitis due to solids and liquids
0.544 0.456 0.000
C34.1 Upper lobe, bronchus or lung
0.544 0.456 0.000
N41 Inflammatory diseases of prostate
0.543 0.457 0.000
C34.8 Overlapping lesion of bronchus and lung
0.543 0.457 0.000
C34.2 Middle lobe, bronchus or lung
0.543 0.457 0.000
C34.0 Main bronchus
0.543 0.457 0.000
D22.9 Melanocytic naevi, unspecified
0.542 0.458 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.542 0.458 0.000
D22.4 Melanocytic naevi of scalp and neck
0.542 0.458 0.000
D22.2 Melanocytic naevi of ear and external auricular canal
0.542 0.458 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.542 0.458 0.000
D22.0 Melanocytic naevi of lip
0.542 0.458 0.000
I51 Complications and ill-defined descriptions of heart disease
0.542 0.458 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.541 0.459 0.000
M24.1 Other articular cartilage disorders
0.541 0.459 0.000
C56 Malignant neoplasm of ovary
0.540 0.460 0.000
H66.4 Suppurative otitis media, unspecified
0.540 0.460 0.000
H66.3 Other chronic suppurative otitis media
0.540 0.460 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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