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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs139961185
log Bayes Factor = 5.63342
Chromosome 11   position 116,807,343  (GRCh37) Explore rs139961185 on Ensembl!
Variant rs139961185 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.998 0.002 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.989 0.011 0.000
Chapter X Diseases of the respiratory system
0.984 0.016 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.977 0.023 0.000
Chapter IX Diseases of the circulatory system
0.976 0.024 0.000
J40-J47 Chronic lower respiratory diseases
0.947 0.053 0.000
Chapter V Mental and behavioural disorders
0.947 0.053 0.000
Chapter II Neoplasms
0.942 0.058 0.000
N81 Female genital prolapse
0.940 0.060 0.000
Chapter VII Diseases of the eye and adnexa
0.925 0.075 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.923 0.077 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.920 0.080 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.895 0.105 0.000
N81.1 Cystocele
0.889 0.111 0.000
N84 Polyp of female genital tract
0.889 0.111 0.000
J44 Other chronic obstructive pulmonary disease
0.880 0.120 0.000
N93 Other abnormal uterine and vaginal bleeding
0.869 0.131 0.000
I20-I25 Ischaemic heart diseases
0.864 0.136 0.000
N40-N51 Diseases of male genital organs
0.863 0.137 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.861 0.139 0.000
R50-R69 General symptoms and signs
0.860 0.140 0.000
N10-N16 Renal tubulo-interstitial diseases
0.850 0.150 0.000
N17-N19 Renal failure
0.849 0.150 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.848 0.152 0.000
E70-E90 Metabolic disorders
0.843 0.157 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.842 0.158 0.000
I30-I52 Other forms of heart disease
0.841 0.159 0.000
I73 Other peripheral vascular diseases
0.837 0.163 0.000
R51 Headache
0.835 0.165 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.833 0.167 0.000
J09-J18 Influenza and pneumonia
0.829 0.170 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.828 0.172 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.828 0.172 0.000
N84.0 Polyp of corpus uteri
0.815 0.185 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.814 0.185 0.000
J43 Emphysema
0.814 0.186 0.000
D10-D36 Benign neoplasms
0.810 0.190 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.807 0.193 0.000
I71 Aortic aneurysm and dissection
0.806 0.194 0.000
N60-N64 Disorders of breast
0.806 0.194 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.804 0.196 0.000
F41 Other anxiety disorders
0.799 0.201 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.799 0.201 0.000
H43-H45 Disorders of vitreous body and globe
0.789 0.211 0.000
H30-H36 Disorders of choroid and retina
0.788 0.212 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.788 0.212 0.000
N81.5 Vaginal enterocele
0.784 0.216 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.780 0.220 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.775 0.225 0.000
R47-R49 Symptoms and signs involving speech and voice
0.771 0.229 0.000
Chapter VIII Diseases of the ear and mastoid process
0.770 0.230 0.000
N43 Hydrocele and spermatocele
0.768 0.232 0.000
I60-I69 Cerebrovascular diseases
0.767 0.233 0.000
J90-J94 Other diseases of pleura
0.767 0.233 0.000
T81 Complications of procedures, not elsewhere classified
0.764 0.236 0.000
J95-J99 Other diseases of the respiratory system
0.763 0.237 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.761 0.239 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.758 0.242 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.757 0.243 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.752 0.248 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.749 0.251 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.749 0.251 0.000
I73.9 Peripheral vascular disease, unspecified
0.746 0.254 0.000
R79 Other abnormal findings of blood chemistry
0.746 0.254 0.000
H25-H28 Disorders of lens
0.745 0.255 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.744 0.256 0.000
I05-I09 Chronic rheumatic heart diseases
0.744 0.256 0.000
C50-C50 Malignant neoplasm of breast
0.742 0.257 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.742 0.258 0.000
Chapter VI Diseases of the nervous system
0.742 0.258 0.000
N19 Unspecified renal failure
0.732 0.268 0.000
J00-J06 Acute upper respiratory infections
0.731 0.268 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.731 0.269 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.729 0.271 0.000
N89 Other noninflammatory disorders of vagina
0.729 0.271 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.727 0.273 0.000
J47 Bronchiectasis
0.726 0.274 0.000
F30-F39 Mood [affective] disorders
0.724 0.276 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.723 0.277 0.000
R94 Abnormal results of function studies
0.720 0.280 0.000
Chapter XXI Factors influencing health status and contact with health services
0.720 0.280 0.000
J43.9 Emphysema, unspecified
0.719 0.281 0.000
J18 Pneumonia, organism unspecified
0.719 0.281 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N13 Obstructive and reflux uropathy
0.717 0.283 0.000
N99-N99 Other disorders of the genitourinary system
0.716 0.284 0.000
N00-N08 Glomerular diseases
0.716 0.284 0.000
Chapter XX External causes of morbidity and mortality
0.714 0.286 0.000
I25 Chronic ischaemic heart disease
0.713 0.287 0.000
I46 Cardiac arrest
0.711 0.289 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.709 0.290 0.000
E10-E14 Diabetes mellitus
0.709 0.291 0.000
N98 Complications associated with artificial fertilisation
0.709 0.291 0.000
N97 Female infertility
0.709 0.291 0.000
N91 Absent, scanty and rare menstruation
0.709 0.291 0.000
N88 Other noninflammatory disorders of cervix uteri
0.709 0.291 0.000
N87 Dysplasia of cervix uteri
0.709 0.291 0.000
N82 Fistulae involving female genital tract
0.709 0.291 0.000
N96 Habitual aborter
0.709 0.291 0.000
N86 Erosion and ectropion of cervix uteri
0.709 0.291 0.000
C15-C26 Malignant neoplasms of digestive organs
0.706 0.294 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.705 0.295 0.000
J60-J70 Lung diseases due to external agents
0.705 0.295 0.000
F41.9 Anxiety disorder, unspecified
0.705 0.295 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.702 0.298 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.700 0.300 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.700 0.300 0.000
I00-I02 Acute rheumatic fever
0.700 0.300 0.000
N43.3 Hydrocele, unspecified
0.700 0.300 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.699 0.301 0.000
N30-N39 Other diseases of urinary system
0.699 0.301 0.000
N20-N23 Urolithiasis
0.698 0.302 0.000
J30-J39 Other diseases of upper respiratory tract
0.697 0.303 0.000
E00-E07 Disorders of thyroid gland
0.693 0.307 0.000
I20 Angina pectoris
0.693 0.307 0.000
F41.2 Mixed anxiety and depressive disorder
0.692 0.307 0.000
N81.2 Incomplete uterovaginal prolapse
0.692 0.307 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.692 0.308 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.691 0.308 0.000
D00-D09 In situ neoplasms
0.689 0.311 0.000
N80 Endometriosis
0.689 0.311 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.689 0.311 0.000
M50-M54 Other dorsopathies
0.688 0.312 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.687 0.313 0.000
J45 Asthma
0.687 0.313 0.000
N25-N29 Other disorders of kidney and ureter
0.687 0.313 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.686 0.314 0.000
N95 Menopausal and other perimenopausal disorders
0.686 0.314 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.684 0.316 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.683 0.317 0.000
J41 Simple and mucopurulent chronic bronchitis
0.679 0.321 0.000
J46 Status asthmaticus
0.679 0.321 0.000
J42 Unspecified chronic bronchitis
0.679 0.321 0.000
J40 Bronchitis, not specified as acute or chronic
0.679 0.321 0.000
F99-F99 Unspecified mental disorder
0.679 0.321 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.679 0.321 0.000
F80-F89 Disorders of psychological development
0.679 0.321 0.000
F70-F79 Mental retardation
0.679 0.321 0.000
F60-F69 Disorders of adult personality and behaviour
0.679 0.321 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.679 0.321 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.679 0.321 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.679 0.321 0.000
I73.0 Raynaud's syndrome
0.678 0.322 0.000
I21 Acute myocardial infarction
0.677 0.323 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.677 0.323 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.676 0.324 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.676 0.324 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.675 0.325 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.675 0.325 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.675 0.325 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.675 0.325 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.675 0.325 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.675 0.325 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.675 0.325 0.000
N92 Excessive, frequent and irregular menstruation
0.675 0.325 0.000
N81.9 Female genital prolapse, unspecified
0.674 0.326 0.000
N81.8 Other female genital prolapse
0.674 0.326 0.000
N81.3 Complete uterovaginal prolapse
0.674 0.326 0.000
N81.0 Female urethrocele
0.674 0.326 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.673 0.327 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.670 0.330 0.000
E86 Volume depletion
0.666 0.334 0.000
D22 Melanocytic naevi
0.665 0.335 0.000
C44 Other malignant neoplasms of skin
0.664 0.336 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.664 0.336 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.663 0.336 0.000
N48 Other disorders of penis
0.663 0.337 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.663 0.337 0.000
H55-H59 Other disorders of eye and adnexa
0.663 0.337 0.000
H53-H54 Visual disturbances and blindness
0.663 0.337 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.663 0.337 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.663 0.337 0.000
H10-H13 Disorders of conjunctiva
0.663 0.337 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.662 0.338 0.000
I78 Diseases of capillaries
0.662 0.338 0.000
I77 Other disorders of arteries and arterioles
0.662 0.338 0.000
I74 Arterial embolism and thrombosis
0.662 0.338 0.000
I72 Other aneurysm
0.662 0.338 0.000
I70 Atherosclerosis
0.662 0.338 0.000
S20-S29 Injuries to the thorax
0.661 0.339 0.000
S70-S79 Injuries to the hip and thigh
0.661 0.339 0.000
D23 Other benign neoplasms of skin
0.660 0.340 0.000
E50-E64 Other nutritional deficiencies
0.660 0.340 0.000
E40-E46 Malnutrition
0.660 0.340 0.000
E20-E35 Disorders of other endocrine glands
0.660 0.340 0.000
H25 Senile cataract
0.660 0.340 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.659 0.341 0.000
S60-S69 Injuries to the wrist and hand
0.655 0.345 0.000
M05-M14 Inflammatory polyarthropathies
0.654 0.346 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.653 0.347 0.000
R53 Malaise and fatigue
0.653 0.347 0.000
N17 Acute renal failure
0.651 0.349 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.651 0.349 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.649 0.351 0.000
S80-S89 Injuries to the knee and lower leg
0.649 0.351 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.648 0.351 0.000
N81.6 Rectocele
0.648 0.352 0.000
C51-C58 Malignant neoplasms of female genital organs
0.646 0.353 0.000
N84.1 Polyp of cervix uteri
0.646 0.354 0.000
J20-J22 Other acute lower respiratory infections
0.645 0.354 0.000
H43 Disorders of vitreous body
0.645 0.354 0.000
C64-C68 Malignant neoplasms of urinary tract
0.644 0.355 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.645 0.355 0.000
R63 Symptoms and signs concerning food and fluid intake
0.644 0.356 0.000
N90.7 Vulvar cyst
0.643 0.356 0.000
H35 Other retinal disorders
0.643 0.357 0.000
M20-M25 Other joint disorders
0.643 0.357 0.000
S40-S49 Injuries to the shoulder and upper arm
0.643 0.357 0.000
R20 Disturbances of skin sensation
0.643 0.357 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.642 0.358 0.000
T79-T79 Certain early complications of trauma
0.642 0.358 0.000
T66-T78 Other and unspecified effects of external causes
0.642 0.358 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.642 0.358 0.000
T33-T35 Frostbite
0.642 0.358 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.642 0.358 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.642 0.358 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.642 0.358 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.642 0.358 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.642 0.358 0.000
T00-T07 Injuries involving multiple body regions
0.642 0.358 0.000
S90-S99 Injuries to the ankle and foot
0.642 0.358 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.642 0.358 0.000
S10-S19 Injuries to the neck
0.642 0.358 0.000
N60 Benign mammary dysplasia
0.642 0.358 0.000
I51 Complications and ill-defined descriptions of heart disease
0.639 0.360 0.000
F17.1 Harmful use
0.638 0.362 0.000
H44 Disorders of globe
0.638 0.362 0.000
N84.9 Polyp of female genital tract, unspecified
0.637 0.362 0.000
N84.8 Polyp of other parts of female genital tract
0.637 0.362 0.000
N84.3 Polyp of vulva
0.637 0.362 0.000
N84.2 Polyp of vagina
0.637 0.362 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.637 0.363 0.000
D17 Benign lipomatous neoplasm
0.637 0.363 0.000
R29.6 Tendency to fall, not elsewhere classified
0.635 0.365 0.000
M65-M68 Disorders of synovium and tendon
0.635 0.365 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.635 0.365 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.632 0.368 0.000
I50 Heart failure
0.632 0.368 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.631 0.369 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.630 0.370 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.629 0.371 0.000
N81.4 Uterovaginal prolapse, unspecified
0.629 0.371 0.000
R94.5 Abnormal results of liver function studies
0.628 0.372 0.000
Chapter XI Diseases of the digestive system
0.625 0.375 0.000
N41 Inflammatory diseases of prostate
0.624 0.376 0.000
D36 Benign neoplasm of other and unspecified sites
0.624 0.376 0.000
I35 Nonrheumatic aortic valve disorders
0.623 0.377 0.000
R47 Speech disturbances, not elsewhere classified
0.623 0.377 0.000
N13.3 Other and unspecified hydronephrosis
0.621 0.379 0.000
J18.9 Pneumonia, unspecified
0.620 0.380 0.000
I24 Other acute ischaemic heart diseases
0.619 0.381 0.000
I23 Certain current complications following acute myocardial infarction
0.619 0.381 0.000
I22 Subsequent myocardial infarction
0.619 0.381 0.000
O00-O08 Pregnancy with abortive outcome
0.619 0.381 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.618 0.381 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.618 0.381 0.000
N45 Orchitis and epididymitis
0.618 0.381 0.000
N42 Other disorders of prostate
0.618 0.381 0.000
N46 Male infertility
0.618 0.381 0.000
N44 Torsion of testis
0.618 0.381 0.000
R26 Abnormalities of gait and mobility
0.618 0.382 0.000
H33 Retinal detachments and breaks
0.617 0.382 0.000
I46.0 Cardiac arrest with successful resuscitation
0.617 0.382 0.000
I44 Atrioventricular and left bundle-branch block
0.617 0.383 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.617 0.383 0.000
E16 Other disorders of pancreatic internal secretion
0.617 0.383 0.000
F48 Other neurotic disorders
0.617 0.383 0.000
F45 Somatoform disorders
0.617 0.383 0.000
F44 Dissociative [conversion] disorders
0.617 0.383 0.000
F43 Reaction to severe stress, and adjustment disorders
0.617 0.383 0.000
F42 Obsessive-compulsive disorder
0.617 0.383 0.000
F40 Phobic anxiety disorders
0.617 0.383 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.617 0.383 0.000
R68 Other general symptoms and signs
0.616 0.384 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.616 0.384 0.000
R62 Lack of expected normal physiological development
0.616 0.384 0.000
R61 Hyperhidrosis
0.616 0.384 0.000
R60 Oedema, not elsewhere classified
0.616 0.384 0.000
R57 Shock, not elsewhere classified
0.616 0.384 0.000
R52 Pain, not elsewhere classified
0.616 0.384 0.000
R64 Cachexia
0.616 0.384 0.000
R58 Haemorrhage, not elsewhere classified
0.616 0.384 0.000
R54 Senility
0.616 0.384 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.616 0.384 0.000
R55 Syncope and collapse
0.616 0.384 0.000
H40-H42 Glaucoma
0.615 0.385 0.000
I34 Nonrheumatic mitral valve disorders
0.614 0.386 0.000
J93 Pneumothorax
0.613 0.387 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.612 0.388 0.000
D50-D53 Nutritional anaemias
0.610 0.390 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.610 0.390 0.000
N15 Other renal tubulo-interstitial diseases
0.610 0.390 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.610 0.390 0.000
N11 Chronic tubulo-interstitial nephritis
0.610 0.390 0.000
N10 Acute tubulo-interstitial nephritis
0.610 0.390 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.608 0.392 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.608 0.392 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.608 0.392 0.000
M80-M85 Disorders of bone density and structure
0.608 0.392 0.000
H90-H95 Other disorders of ear
0.605 0.394 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.605 0.395 0.000
E88 Other metabolic disorders
0.605 0.395 0.000
E85 Amyloidosis
0.605 0.395 0.000
E84 Cystic fibrosis
0.605 0.395 0.000
E83 Disorders of mineral metabolism
0.605 0.395 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.605 0.395 0.000
E79 Disorders of purine and pyrimidine metabolism
0.605 0.395 0.000
E77 Disorders of glycoprotein metabolism
0.605 0.395 0.000
E76 Disorders of glycosaminoglycan metabolism
0.605 0.395 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.605 0.395 0.000
E74 Other disorders of carbohydrate metabolism
0.605 0.395 0.000
E73 Lactose intolerance
0.605 0.395 0.000
E72 Other disorders of amino-acid metabolism
0.605 0.395 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.605 0.395 0.000
E70 Disorders of aromatic amino-acid metabolism
0.605 0.395 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.605 0.395 0.000
J98 Other respiratory disorders
0.604 0.396 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.604 0.396 0.000
R77 Other abnormalities of plasma proteins
0.604 0.396 0.000
R76 Other abnormal immunological findings in serum
0.604 0.396 0.000
R74 Abnormal serum enzyme levels
0.604 0.396 0.000
R73 Elevated blood glucose level
0.604 0.396 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.604 0.396 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.604 0.396 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.604 0.396 0.000
R71 Abnormality of red blood cells
0.604 0.396 0.000
I52 Other heart disorders in diseases classified elsewhere
0.603 0.397 0.000
I49 Other cardiac arrhythmias
0.603 0.397 0.000
I48 Atrial fibrillation and flutter
0.603 0.397 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.603 0.397 0.000
I42 Cardiomyopathy
0.603 0.397 0.000
I41 Myocarditis in diseases classified elsewhere
0.603 0.397 0.000
I40 Acute myocarditis
0.603 0.397 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.603 0.397 0.000
I37 Pulmonary valve disorders
0.603 0.397 0.000
I36 Nonrheumatic tricuspid valve disorders
0.603 0.397 0.000
I33 Acute and subacute endocarditis
0.603 0.397 0.000
I32 Pericarditis in diseases classified elsewhere
0.603 0.397 0.000
I31 Other diseases of pericardium
0.603 0.397 0.000
I30 Acute pericarditis
0.603 0.397 0.000
I38 Endocarditis, valve unspecified
0.603 0.397 0.000
E78.0 Pure hypercholesterolaemia
0.603 0.397 0.000
M40-M43 Deforming dorsopathies
0.602 0.397 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.602 0.398 0.000
M54 Dorsalgia
0.601 0.399 0.000
J84 Other interstitial pulmonary diseases
0.601 0.399 0.000
F17.2 Dependence syndrome
0.601 0.399 0.000
I73.8 Other specified peripheral vascular diseases
0.600 0.399 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.600 0.399 0.000
R21 Rash and other nonspecific skin eruption
0.600 0.400 0.000
I95 Hypotension
0.600 0.400 0.000
C50 Malignant neoplasm of breast
0.600 0.400 0.000
N63 Unspecified lump in breast
0.599 0.400 0.000
C34 Malignant neoplasm of bronchus and lung
0.599 0.401 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.599 0.401 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.597 0.403 0.000
T87 Complications peculiar to reattachment and amputation
0.597 0.403 0.000
T86 Failure and rejection of transplanted organs and tissues
0.597 0.403 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.597 0.403 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.597 0.403 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.597 0.403 0.000
E78.5 Hyperlipidaemia, unspecified
0.595 0.405 0.000
J17 Pneumonia in diseases classified elsewhere
0.595 0.405 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.595 0.405 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.595 0.405 0.000
J12 Viral pneumonia, not elsewhere classified
0.595 0.405 0.000
J11 Influenza, virus not identified
0.595 0.405 0.000
J10 Influenza due to identified influenza virus
0.595 0.405 0.000
J14 Pneumonia due to Haemophilus influenzae
0.595 0.405 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.595 0.405 0.000
J09 Influenza due to certain identified influenza virus
0.595 0.405 0.000
N62 Hypertrophy of breast
0.594 0.405 0.000
R27 Other lack of coordination
0.594 0.406 0.000
R25 Abnormal involuntary movements
0.594 0.406 0.000
R23 Other skin changes
0.593 0.406 0.000
N39 Other disorders of urinary system
0.590 0.410 0.000
S00-S09 Injuries to the head
0.590 0.410 0.000
S50-S59 Injuries to the elbow and forearm
0.590 0.410 0.000
N85.2 Hypertrophy of uterus
0.590 0.410 0.000
H36 Retinal disorders in diseases classified elsewhere
0.589 0.411 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.589 0.411 0.000
C60-C63 Malignant neoplasms of male genital organs
0.586 0.414 0.000
E10 Insulin-dependent diabetes mellitus
0.585 0.415 0.000
N93.0 Postcoital and contact bleeding
0.585 0.415 0.000
N18 Chronic renal failure
0.584 0.415 0.000
O85-O92 Complications predominantly related to the puerperium
0.584 0.416 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.584 0.416 0.000
J43.8 Other emphysema
0.584 0.416 0.000
J43.2 Centrilobular emphysema
0.584 0.416 0.000
J43.1 Panlobular emphysema
0.584 0.416 0.000
J43.0 MacLeod's syndrome
0.584 0.416 0.000
N40 Hyperplasia of prostate
0.584 0.416 0.000
I47 Paroxysmal tachycardia
0.583 0.417 0.000
Z96 Presence of other functional implants
0.581 0.419 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.581 0.419 0.000
D32 Benign neoplasm of meninges
0.581 0.419 0.000
D31 Benign neoplasm of eye and adnexa
0.581 0.419 0.000
D30 Benign neoplasm of urinary organs
0.581 0.419 0.000
D29 Benign neoplasm of male genital organs
0.581 0.419 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.581 0.419 0.000
D26 Other benign neoplasms of uterus
0.581 0.419 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.581 0.419 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.581 0.419 0.000
D19 Benign neoplasm of mesothelial tissue
0.581 0.419 0.000
D16 Benign neoplasm of bone and articular cartilage
0.581 0.419 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.581 0.419 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.581 0.419 0.000
D11 Benign neoplasm of major salivary glands
0.581 0.419 0.000
D10 Benign neoplasm of mouth and pharynx
0.581 0.419 0.000
D34 Benign neoplasm of thyroid gland
0.581 0.419 0.000
D27 Benign neoplasm of ovary
0.581 0.419 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.579 0.421 0.000
M91-M94 Chondropathies
0.579 0.421 0.000
M86-M90 Other osteopathies
0.579 0.421 0.000
M60-M63 Disorders of muscles
0.579 0.421 0.000
M00-M03 Infectious arthropathies
0.579 0.421 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.578 0.422 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.578 0.422 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.578 0.422 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.578 0.422 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.578 0.422 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.578 0.422 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.578 0.422 0.000
I71.0 Dissection of aorta [any part]
0.578 0.422 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.578 0.422 0.000
N64 Other disorders of breast
0.578 0.422 0.000
N61 Inflammatory disorders of breast
0.578 0.422 0.000
D60-D64 Aplastic and other anaemias
0.578 0.422 0.000
I08 Multiple valve diseases
0.577 0.423 0.000
I45 Other conduction disorders
0.577 0.423 0.000
R50 Fever of unknown origin
0.577 0.423 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.576 0.424 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.576 0.424 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.576 0.424 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.576 0.424 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.576 0.424 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.576 0.424 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.576 0.424 0.000
F11 Mental and behavioural disorders due to use of opioids
0.576 0.424 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.573 0.427 0.000
F41.8 Other specified anxiety disorders
0.573 0.427 0.000
F41.3 Other mixed anxiety disorders
0.573 0.427 0.000
F41.1 Generalised anxiety disorder
0.573 0.427 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.573 0.427 0.000
D25 Leiomyoma of uterus
0.573 0.427 0.000
R56 Convulsions, not elsewhere classified
0.572 0.428 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.572 0.428 0.000
D24 Benign neoplasm of breast
0.570 0.429 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.570 0.430 0.000
D18 Haemangioma and lymphangioma, any site
0.568 0.432 0.000
E87.2 Acidosis
0.567 0.433 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.566 0.434 0.000
F32 Depressive episode
0.565 0.435 0.000
H34 Retinal vascular occlusions
0.565 0.435 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.565 0.435 0.000
H31 Other disorders of choroid
0.565 0.435 0.000
H30 Chorioretinal inflammation
0.565 0.435 0.000
I67 Other cerebrovascular diseases
0.565 0.435 0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.565 0.435 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.565 0.435 0.000
N90.6 Hypertrophy of vulva
0.565 0.435 0.000
N90.5 Atrophy of vulva
0.565 0.435 0.000
N90.4 Leukoplakia of vulva
0.565 0.435 0.000
N90.3 Dysplasia of vulva, unspecified
0.565 0.435 0.000
N90.2 Severe vulvar dysplasia, not elsewhere classified
0.565 0.435 0.000
N90.1 Moderate vulvar dysplasia
0.565 0.435 0.000
N90.0 Mild vulvar dysplasia
0.565 0.435 0.000
Chapter I Certain infectious and parasitic diseases
0.565 0.435 0.000
O80-O84 Delivery
0.565 0.435 0.000
R59 Enlarged lymph nodes
0.564 0.435 0.000
Z95.1 Presence of aortocoronary bypass graft
0.564 0.436 0.000
R05 Cough
0.563 0.437 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.563 0.437 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.562 0.438 0.000
M45-M49 Spondylopathies
0.561 0.439 0.000
Z87 Personal history of other diseases and conditions
0.560 0.440 0.000
C43 Malignant melanoma of skin
0.559 0.441 0.000
H25.1 Senile nuclear cataract
0.557 0.443 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.556 0.444 0.000
I63 Cerebral infarction
0.556 0.444 0.000
D80-D89 Certain disorders involving the immune mechanism
0.556 0.444 0.000
D55-D59 Haemolytic anaemias
0.556 0.444 0.000
J18.1 Lobar pneumonia, unspecified
0.555 0.444 0.000
R30-R39 Symptoms and signs involving the urinary system
0.555 0.445 0.000
I69 Sequelae of cerebrovascular disease
0.555 0.445 0.000
C44.6 Skin of upper limb, including shoulder
0.553 0.446 0.000
E07 Other disorders of thyroid
0.553 0.447 0.000
R49 Voice disturbances
0.552 0.447 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.552 0.447 0.000
N85.0 Endometrial glandular hyperplasia
0.552 0.448 0.000
H80-H83 Diseases of inner ear
0.552 0.448 0.000
H65-H75 Diseases of middle ear and mastoid
0.552 0.448 0.000
H60-H62 Diseases of external ear
0.552 0.448 0.000
L40-L45 Papulosquamous disorders
0.551 0.449 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.551 0.449 0.000
N43.4 Spermatocele
0.550 0.449 0.000
N43.2 Other hydrocele
0.550 0.449 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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