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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs140436982
log Bayes Factor = 4.22646
Chromosome 14   position 24,504,121  (GRCh37) Explore rs140436982 on Ensembl!
Variant rs140436982 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
S80-S89 Injuries to the knee and lower leg
0.997 0.003 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.993 0.007 0.000
Chapter I Certain infectious and parasitic diseases
0.991 0.009 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.986 0.014 0.000
S81 Open wound of lower leg
0.976 0.024 0.000
Chapter VI Diseases of the nervous system
0.975 0.025 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.975 0.025 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.970 0.030 0.000
Y43 Primarily systemic agents
0.951 0.049 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.944 0.056 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.942 0.058 0.000
M40-M43 Deforming dorsopathies
0.936 0.064 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.931 0.069 0.000
D69 Purpura and other haemorrhagic conditions
0.930 0.070 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.928 0.072 0.000
W00-W19 Falls
0.926 0.074 0.000
M80-M85 Disorders of bone density and structure
0.925 0.075 0.000
M45-M49 Spondylopathies
0.924 0.076 0.000
A30-A49 Other bacterial diseases
0.923 0.077 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.914 0.086 0.000
S81.0 Open wound of knee
0.913 0.087 0.000
G90-G99 Other disorders of the nervous system
0.912 0.088 0.000
M48 Other spondylopathies
0.904 0.096 0.000
Y43.3 Other antineoplastic drugs
0.904 0.096 0.000
R42 Dizziness and giddiness
0.902 0.098 0.000
D69.6 Thrombocytopenia, unspecified
0.901 0.099 0.000
M43 Other deforming dorsopathies
0.900 0.100 0.000
S82 Fracture of lower leg, including ankle
0.898 0.102 0.000
B95-B98 Bacterial, viral and other infectious agents
0.896 0.104 0.000
T51 Toxic effect of alcohol
0.894 0.106 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.891 0.109 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.885 0.115 0.000
M48.0 Spinal stenosis
0.880 0.120 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.880 0.120 0.000
M48.06 Spinal stenosis (Lumbar region)
0.877 0.123 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.875 0.125 0.000
M43.1 Spondylolisthesis
0.873 0.127 0.000
T51.0 Ethanol
0.873 0.127 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.873 0.127 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.873 0.127 0.000
A41 Other septicaemia
0.870 0.130 0.000
R40 Somnolence, stupor and coma
0.866 0.134 0.000
R41.0 Disorientation, unspecified
0.864 0.136 0.000
D60-D64 Aplastic and other anaemias
0.862 0.138 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.859 0.141 0.000
D68 Other coagulation defects
0.857 0.143 0.000
S81.8 Open wound of other parts of lower leg
0.856 0.144 0.000
T66-T78 Other and unspecified effects of external causes
0.846 0.154 0.000
Y40 Systemic antibiotics
0.843 0.157 0.000
D80-D89 Certain disorders involving the immune mechanism
0.842 0.158 0.000
S86 Injury of muscle and tendon at lower leg level
0.841 0.159 0.000
G30-G32 Other degenerative diseases of the nervous system
0.839 0.161 0.000
B99-B99 Other infectious diseases
0.832 0.168 0.000
S82.8 Fractures of other parts of lower leg
0.831 0.169 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.828 0.172 0.000
Chapter XXII Codes for special purposes
0.821 0.179 0.000
Y48 Anaesthetics and therapeutic gases
0.820 0.180 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.818 0.182 0.000
W19 Unspecified fall
0.817 0.183 0.000
Y57 Other and unspecified drugs and medicaments
0.814 0.186 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.813 0.187 0.000
T18 Foreign body in alimentary tract
0.811 0.189 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.808 0.192 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.807 0.193 0.000
W10 Fall on and from stairs and steps
0.807 0.193 0.000
S82.0 Fracture of patella
0.807 0.193 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.805 0.195 0.000
A00-A09 Intestinal infectious diseases
0.805 0.195 0.000
M91-M94 Chondropathies
0.805 0.195 0.000
T93 Sequelae of injuries of lower limb
0.804 0.196 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.803 0.197 0.000
M84 Disorders of continuity of bone
0.799 0.201 0.000
S81.7 Multiple open wounds of lower leg
0.799 0.201 0.000
Y43.1 Antineoplastic antimetabolites
0.797 0.202 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.796 0.204 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.795 0.205 0.000
M80 Osteoporosis with pathological fracture
0.790 0.210 0.000
X20-X29 Contact with venomous animals and plants
0.789 0.211 0.000
R40.0 Somnolence
0.788 0.212 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.782 0.217 0.000
W19.2 School, other institution and public administrative area
0.782 0.218 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.782 0.218 0.000
A41.8 Other specified septicaemia
0.782 0.218 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.781 0.218 0.000
S10-S19 Injuries to the neck
0.779 0.221 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.778 0.222 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.775 0.225 0.000
G70-G73 Diseases of myoneural junction and muscle
0.774 0.226 0.000
R47-R49 Symptoms and signs involving speech and voice
0.772 0.228 0.000
M85 Other disorders of bone density and structure
0.770 0.230 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.765 0.235 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.763 0.237 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.758 0.242 0.000
R29.6 Tendency to fall, not elsewhere classified
0.757 0.243 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.757 0.243 0.000
D50-D53 Nutritional anaemias
0.756 0.244 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.755 0.244 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.755 0.245 0.000
D68.8 Other specified coagulation defects
0.753 0.247 0.000
S80 Superficial injury of lower leg
0.752 0.248 0.000
X60-X84 Intentional self-harm
0.752 0.248 0.000
T92 Sequelae of injuries of upper limb
0.748 0.251 0.000
Y00-Y09 Assault
0.748 0.252 0.000
X10-X19 Contact with heat and hot substances
0.748 0.252 0.000
G90 Disorders of autonomic nervous system
0.745 0.255 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.745 0.255 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.743 0.257 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.742 0.258 0.000
S82.00 Fracture of patella (closed)
0.741 0.259 0.000
S89 Other and unspecified injuries of lower leg
0.741 0.259 0.000
B35-B49 Mycoses
0.741 0.259 0.000
S90-S99 Injuries to the ankle and foot
0.739 0.261 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.739 0.261 0.000
G91 Hydrocephalus
0.738 0.262 0.000
G03 Meningitis due to other and unspecified causes
0.737 0.263 0.000
Y89 Sequelae of other external causes
0.736 0.263 0.000
Q60-Q64 Congenital malformations of the urinary system
0.735 0.265 0.000
V20-V29 Motorcycle rider injured in transport accident
0.735 0.265 0.000
M65-M68 Disorders of synovium and tendon
0.735 0.265 0.000
W06 Fall involving bed
0.734 0.266 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.734 0.266 0.000
D86 Sarcoidosis
0.733 0.267 0.000
T91 Sequelae of injuries of neck and trunk
0.731 0.269 0.000
D62 Acute posthaemorrhagic anaemia
0.731 0.269 0.000
T18.1 Foreign body in oesophagus
0.730 0.270 0.000
S81.9 Open wound of lower leg, part unspecified
0.730 0.270 0.000
Y40.0 Penicillins
0.730 0.270 0.000
G30 Alzheimer's disease
0.729 0.271 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.729 0.271 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.729 0.271 0.000
M41 Scoliosis
0.727 0.273 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.727 0.273 0.000
Chapter XXI Factors influencing health status and contact with health services
0.726 0.274 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.726 0.274 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.723 0.277 0.000
R40.2 Coma, unspecified
0.722 0.278 0.000
T78 Adverse effects, not elsewhere classified
0.722 0.278 0.000
W10.8 Other specified place
0.722 0.278 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.722 0.278 0.000
D61 Other aplastic anaemias
0.720 0.280 0.000
V80-V89 Other land transport accidents
0.720 0.280 0.000
S83.2 Tear of meniscus, current
0.720 0.280 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.719 0.281 0.000
B99 Other and unspecified infectious diseases
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
A80-A89 Viral infections of the central nervous system
0.717 0.283 0.000
B15-B19 Viral hepatitis
0.716 0.283 0.000
D69.0 Allergic purpura
0.716 0.284 0.000
M48.04 Spinal stenosis (Thoracic region)
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.716 0.284 0.000
X50-X57 Overexertion, travel and privation
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
W50-W64 Exposure to animate mechanical forces
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V40-V49 Car occupant injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
S88 Traumatic amputation of lower leg
0.715 0.285 0.000
S87 Crushing injury of lower leg
0.715 0.285 0.000
S85 Injury of blood vessels at lower leg level
0.715 0.285 0.000
S84 Injury of nerves at lower leg level
0.715 0.285 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.714 0.286 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.714 0.286 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.714 0.286 0.000
Y42.7 Androgens and anabolic congeners
0.713 0.287 0.000
D55-D59 Haemolytic anaemias
0.712 0.288 0.000
A40 Streptococcal septicaemia
0.712 0.288 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.712 0.288 0.000
T63 Toxic effect of contact with venomous animals
0.711 0.289 0.000
G95 Other diseases of spinal cord
0.711 0.289 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.710 0.290 0.000
B65-B83 Helminthiases
0.710 0.290 0.000
B50-B64 Protozoal diseases
0.710 0.290 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.710 0.290 0.000
A75-A79 Rickettsioses
0.710 0.290 0.000
A70-A74 Other diseases caused by chlamydiae
0.710 0.290 0.000
A65-A69 Other spirochaetal diseases
0.710 0.290 0.000
A20-A28 Certain zoonotic bacterial diseases
0.710 0.290 0.000
A15-A19 Tuberculosis
0.710 0.290 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.710 0.290 0.000
S40-S49 Injuries to the shoulder and upper arm
0.709 0.291 0.000
Z73 Problems related to life-management difficulty
0.708 0.292 0.000
Y59 Other and unspecified vaccines and biological substances
0.707 0.293 0.000
Y58 Bacterial vaccines
0.707 0.293 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.707 0.293 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.707 0.293 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.707 0.293 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.707 0.293 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.707 0.293 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.707 0.293 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.707 0.293 0.000
D68.6 Other Thrombophilia
0.704 0.296 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.704 0.296 0.000
R44.1 Visual hallucinations
0.702 0.298 0.000
Z73.9 Problem related to life-management difficulty, unspecified
0.702 0.298 0.000
W20-W49 Exposure to inanimate mechanical forces
0.702 0.298 0.000
T90 Sequelae of injuries of head
0.701 0.299 0.000
A49 Bacterial infection of unspecified site
0.701 0.299 0.000
Y48.4 Anaesthetic, unspecified
0.701 0.299 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.700 0.299 0.000
G93 Other disorders of brain
0.700 0.300 0.000
V10-V19 Pedal cyclist injured in transport accident
0.700 0.300 0.000
M00-M03 Infectious arthropathies
0.699 0.301 0.000
M46 Other inflammatory spondylopathies
0.699 0.301 0.000
R49 Voice disturbances
0.696 0.304 0.000
D67 Hereditary factor IX deficiency
0.696 0.304 0.000
D66 Hereditary factor VIII deficiency
0.696 0.304 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.696 0.304 0.000
Y43.4 Immunosuppressive agents
0.695 0.305 0.000
Y52 Agents primarily affecting the cardiovascular system
0.695 0.305 0.000
G54 Nerve root and plexus disorders
0.695 0.305 0.000
Z75 Problems related to medical facilities and other health care
0.693 0.307 0.000
S82.2 Fracture of shaft of tibia
0.692 0.308 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.692 0.308 0.000
Y57.9 Drug or medicament, unspecified
0.692 0.308 0.000
G20-G26 Extrapyramidal and movement disorders
0.692 0.308 0.000
M49 Spondylopathies in diseases classified elsewhere
0.691 0.308 0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level
0.691 0.309 0.000
T94.1 Sequelae of injuries, not specified by body region
0.689 0.311 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.687 0.312 0.000
T98 Sequelae of other and unspecified effects of external causes
0.686 0.314 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.685 0.315 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.685 0.315 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.685 0.315 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.682 0.318 0.000
Y43.9 Primarily systemic agent, unspecified
0.682 0.318 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.682 0.318 0.000
Y43.6 Enzymes, not elsewhere classified
0.682 0.318 0.000
Y43.5 Acidifying and alkalising agents
0.682 0.318 0.000
Y43.2 Antineoplastic natural products
0.682 0.318 0.000
Y43.0 Antiallergic and antiemetic drugs
0.682 0.318 0.000
R26 Abnormalities of gait and mobility
0.680 0.320 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.679 0.320 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.679 0.321 0.000
D68.0 Von Willebrand's disease
0.678 0.322 0.000
G96 Other disorders of central nervous system
0.677 0.322 0.000
M81 Osteoporosis without pathological fracture
0.677 0.323 0.000
T95 Sequelae of burns, corrosions and frostbite
0.677 0.323 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.677 0.323 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.677 0.323 0.000
D64 Other anaemias
0.675 0.325 0.000
T65 Toxic effect of other and unspecified substances
0.675 0.325 0.000
T62 Toxic effect of other noxious substances eaten as food
0.675 0.325 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.675 0.325 0.000
T60 Toxic effect of pesticides
0.675 0.325 0.000
T59 Toxic effect of other gases, fumes and vapours
0.675 0.325 0.000
T57 Toxic effect of other inorganic substances
0.675 0.325 0.000
T56 Toxic effect of metals
0.675 0.325 0.000
T54 Toxic effect of corrosive substances
0.675 0.325 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.675 0.325 0.000
T52 Toxic effect of organic solvents
0.675 0.325 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.675 0.325 0.000
T58 Toxic effect of carbon monoxide
0.675 0.325 0.000
T55 Toxic effect of soaps and detergents
0.675 0.325 0.000
M43.19 Spondylolisthesis (Site unspecified)
0.673 0.327 0.000
M42 Spinal osteochondrosis
0.671 0.329 0.000
M40 Kyphosis and lordosis
0.671 0.329 0.000
R46 Symptoms and signs involving appearance and behaviour
0.669 0.330 0.000
Q43 Other congenital malformations of intestine
0.669 0.331 0.000
Y88 Sequelae of surgical and medical care as external cause
0.669 0.331 0.000
R45 Symptoms and signs involving emotional state
0.669 0.331 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.668 0.331 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.668 0.332 0.000
R43 Disturbances of smell and taste
0.668 0.332 0.000
D69.9 Haemorrhagic condition, unspecified
0.667 0.333 0.000
D69.8 Other specified haemorrhagic conditions
0.667 0.333 0.000
D69.5 Secondary thrombocytopenia
0.667 0.333 0.000
D69.4 Other primary thrombocytopenia
0.667 0.333 0.000
D69.2 Other nonthrombocytopenic purpura
0.667 0.333 0.000
D69.1 Qualitative platelet defects
0.667 0.333 0.000
T79-T79 Certain early complications of trauma
0.665 0.334 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.665 0.335 0.000
Y86 Sequelae of other accidents
0.664 0.336 0.000
W18 Other fall on same level
0.664 0.336 0.000
W17 Other fall from one level to another
0.664 0.336 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.664 0.336 0.000
W15 Fall from cliff
0.664 0.336 0.000
W14 Fall from tree
0.664 0.336 0.000
W12 Fall on and from scaffolding
0.664 0.336 0.000
W11 Fall on and from ladder
0.664 0.336 0.000
W09 Fall involving playground equipment
0.664 0.336 0.000
W08 Fall involving other furniture
0.664 0.336 0.000
W05 Fall involving wheelchair
0.664 0.336 0.000
W04 Fall while being carried or supported by other persons
0.664 0.336 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.664 0.336 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.664 0.336 0.000
W00 Fall on same level involving ice and snow
0.664 0.336 0.000
M83 Adult osteomalacia
0.663 0.337 0.000
M82 Osteoporosis in diseases classified elsewhere
0.663 0.337 0.000
S86.8 Injury of other muscles and tendons at lower leg level
0.662 0.338 0.000
A48 Other bacterial diseases, not elsewhere classified
0.662 0.338 0.000
A44 Bartonellosis
0.662 0.338 0.000
A43 Nocardiosis
0.662 0.338 0.000
A42 Actinomycosis
0.662 0.338 0.000
A39 Meningococcal infection
0.662 0.338 0.000
A37 Whooping cough
0.662 0.338 0.000
A36 Diphtheria
0.662 0.338 0.000
A32 Listeriosis
0.662 0.338 0.000
A31 Infection due to other mycobacteria
0.662 0.338 0.000
A30 Leprosy [Hansen's disease]
0.662 0.338 0.000
A38 Scarlet fever
0.662 0.338 0.000
A35 Other tetanus
0.662 0.338 0.000
A34 Obstetrical tetanus
0.662 0.338 0.000
A33 Tetanus neonatorum
0.662 0.338 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.659 0.341 0.000
M43.0 Spondylolysis
0.659 0.341 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.657 0.343 0.000
G50 Disorders of trigeminal nerve
0.657 0.343 0.000
B25-B34 Other viral diseases
0.657 0.343 0.000
M84.4 Pathological fracture, not elsewhere classified
0.657 0.343 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.656 0.344 0.000
M94 Other disorders of cartilage
0.655 0.345 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.655 0.345 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.655 0.345 0.000
Q35-Q37 Cleft lip and cleft palate
0.655 0.345 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.655 0.345 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.655 0.345 0.000
T87 Complications peculiar to reattachment and amputation
0.655 0.345 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.654 0.346 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.654 0.346 0.000
G92 Toxic encephalopathy
0.654 0.346 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.654 0.346 0.000
S50-S59 Injuries to the elbow and forearm
0.653 0.347 0.000
T78.4 Allergy, unspecified
0.653 0.347 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.652 0.348 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.651 0.349 0.000
G51 Facial nerve disorders
0.651 0.349 0.000
G30.9 Alzheimer's disease, unspecified
0.650 0.350 0.000
M20-M25 Other joint disorders
0.650 0.350 0.000
A41.9 Septicaemia, unspecified
0.650 0.350 0.000
T86 Failure and rejection of transplanted organs and tissues
0.649 0.350 0.000
M48.9 Spondylopathy, unspecified
0.648 0.351 0.000
M48.8 Other specified spondylopathies
0.648 0.351 0.000
M48.4 Fatigue fracture of vertebra
0.648 0.351 0.000
M48.3 Traumatic spondylopathy
0.648 0.351 0.000
M48.2 Kissing spine
0.648 0.351 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.648 0.351 0.000
T17 Foreign body in respiratory tract
0.648 0.352 0.000
Q28 Other congenital malformations of circulatory system
0.648 0.352 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.647 0.353 0.000
S32 Fracture of lumbar spine and pelvis
0.646 0.354 0.000
A02 Other Salmonella infections
0.646 0.354 0.000
M85.0 Fibrous dysplasia (monostotic)
0.645 0.355 0.000
T18.5 Foreign body in anus and rectum
0.645 0.355 0.000
M43.9 Deforming dorsopathy, unspecified
0.645 0.355 0.000
M43.8 Other specified deforming dorsopathies
0.645 0.355 0.000
M43.6 Torticollis
0.645 0.355 0.000
M43.5 Other recurrent vertebral subluxation
0.645 0.355 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.645 0.355 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.645 0.355 0.000
M43.2 Other fusion of spine
0.645 0.355 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.644 0.356 0.000
S82.9 Fracture of lower leg, part unspecified
0.644 0.356 0.000
S82.7 Multiple fractures of lower leg
0.644 0.356 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.643 0.357 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.642 0.358 0.000
B02 Zoster [herpes zoster]
0.641 0.359 0.000
T51.8 Other alcohols
0.641 0.359 0.000
T51.3 Fusel oil
0.641 0.359 0.000
T51.2 2-Propanol
0.641 0.359 0.000
T51.1 Methanol
0.641 0.359 0.000
T19 Foreign body in genito-urinary tract
0.639 0.361 0.000
T15 Foreign body on external eye
0.639 0.361 0.000
T16 Foreign body in ear
0.639 0.361 0.000
Y89.9 Sequelae of unspecified external cause
0.639 0.361 0.000
X23 Contact with hornets, wasps and bees
0.638 0.361 0.000
Y40.3 Macrolides
0.637 0.362 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.637 0.363 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.636 0.364 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.636 0.364 0.000
G03.9 Meningitis, unspecified
0.636 0.364 0.000
T68 Hypothermia
0.635 0.365 0.000
R41.1 Anterograde amnesia
0.635 0.365 0.000
Y44 Agents primarily affecting blood constituents
0.634 0.366 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.633 0.367 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.632 0.367 0.000
R41.2 Retrograde amnesia
0.632 0.368 0.000
S82.4 Fracture of fibula alone
0.632 0.368 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.631 0.369 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.631 0.369 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.631 0.369 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.631 0.369 0.000
M86-M90 Other osteopathies
0.631 0.369 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.631 0.369 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.631 0.369 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.631 0.369 0.000
G00 Bacterial meningitis, not elsewhere classified
0.631 0.369 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.631 0.369 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.631 0.369 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.631 0.369 0.000
G60 Hereditary and idiopathic neuropathy
0.630 0.369 0.000
M67 Other disorders of synovium and tendon
0.629 0.371 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.628 0.372 0.000
S82.81 Fractures of other parts of lower leg (open)
0.627 0.373 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.626 0.374 0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)
0.626 0.374 0.000
M43.15 Spondylolisthesis (Thoracolumbar region)
0.626 0.374 0.000
M43.14 Spondylolisthesis (Thoracic region)
0.626 0.374 0.000
M43.13 Spondylolisthesis (Cervicothoracic region)
0.626 0.374 0.000
M43.12 Spondylolisthesis (Cervical region)
0.626 0.374 0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)
0.626 0.374 0.000
M43.10 Spondylolisthesis (Multiple sites in spine)
0.626 0.374 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.625 0.375 0.000
G97.0 Cerebrospinal fluid leak from spinal puncture
0.625 0.375 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.625 0.375 0.000
S36 Injury of intra-abdominal organs
0.624 0.376 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.624 0.376 0.000
A41.4 Septicaemia due to anaerobes
0.624 0.376 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.624 0.376 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.624 0.376 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.623 0.377 0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.623 0.377 0.000
R27 Other lack of coordination
0.623 0.377 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.623 0.377 0.000
Q00-Q07 Congenital malformations of the nervous system
0.622 0.378 0.000
G58 Other mononeuropathies
0.622 0.378 0.000
R40.1 Stupor
0.621 0.379 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.621 0.379 0.000
O00-O08 Pregnancy with abortive outcome
0.620 0.380 0.000
D61.9 Aplastic anaemia, unspecified
0.619 0.381 0.000
Q61 Cystic kidney disease
0.619 0.381 0.000
M93 Other osteochondropathies
0.618 0.381 0.000
Z75.5 Holiday relief care
0.618 0.382 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.618 0.382 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.618 0.382 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.617 0.383 0.000
Q80-Q89 Other congenital malformations
0.616 0.384 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.616 0.384 0.000
Q21 Congenital malformations of cardiac septa
0.616 0.384 0.000
S83.7 Injury to multiple structures of knee
0.616 0.384 0.000
S83.6 Sprain and strain of other and unspecified parts of knee
0.616 0.384 0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee
0.616 0.384 0.000
S83.3 Tear of articular cartilage of knee, current
0.616 0.384 0.000
S83.1 Dislocation of knee
0.616 0.384 0.000
S83.0 Dislocation of patella
0.616 0.384 0.000
D68.5 Primary Thrombophilia
0.616 0.384 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.616 0.384 0.000
Q50-Q56 Congenital malformations of genital organs
0.615 0.384 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.615 0.384 0.000
D68.4 Acquired coagulation factor deficiency
0.614 0.386 0.000
D68.1 Hereditary factor XI deficiency
0.614 0.386 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.614 0.386 0.000
U88 Agent resistant to multiple antibiotics
0.614 0.386 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.614 0.386 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.614 0.386 0.000
Y40.8 Other systemic antibiotics
0.613 0.387 0.000
R49.0 Dysphonia
0.613 0.387 0.000
D86.0 Sarcoidosis of lung
0.613 0.387 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.612 0.388 0.000
G62 Other polyneuropathies
0.609 0.391 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.609 0.391 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.608 0.392 0.000
W13 Fall from, out of or through building or structure
0.608 0.392 0.000
B00 Herpesviral [herpes simplex] infections
0.608 0.392 0.000
T93.2 Sequelae of other fractures of lower limb
0.608 0.392 0.000
G54.4 Lumbosacral root disorders, not elsewhere classified
0.607 0.392 0.000
T75 Effects of other external causes
0.607 0.393 0.000
T74 Maltreatment syndromes
0.607 0.393 0.000
T73 Effects of other deprivation
0.607 0.393 0.000
T70 Effects of air pressure and water pressure
0.607 0.393 0.000
T69 Other effects of reduced temperature
0.607 0.393 0.000
T67 Effects of heat and light
0.607 0.393 0.000
T71 Asphyxiation
0.607 0.393 0.000
T66 Unspecified effects of radiation
0.607 0.393 0.000
S00-S09 Injuries to the head
0.607 0.393 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.606 0.394 0.000
D50 Iron deficiency anaemia
0.606 0.394 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.606 0.394 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.604 0.395 0.000
Y40.7 Antifungal antibiotics, systemically used
0.604 0.396 0.000
Y40.6 Rifamycins
0.604 0.396 0.000
Y40.5 Aminoglycosides
0.604 0.396 0.000
Y40.4 Tetracyclines
0.604 0.396 0.000
Y40.2 Chloramphenicol group
0.604 0.396 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.604 0.396 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.604 0.396 0.000
A49.8 Other bacterial infections of unspecified site
0.604 0.396 0.000
D84 Other immunodeficiencies
0.604 0.396 0.000
D83 Common variable immunodeficiency
0.604 0.396 0.000
D82 Immunodeficiency associated with other major defects
0.604 0.396 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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