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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1419635
log Bayes Factor = 42.2963
Chromosome 6   position 29,355,918  (GRCh37) Explore rs1419635 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.004 0.996
E10-E14 Diabetes mellitus
0.000 0.025 0.975
E10.1 With ketoacidosis
0.000 0.029 0.971
E10.2 With renal complications
0.000 0.038 0.962
E13 Other specified diabetes mellitus
0.000 0.049 0.951
E13.9 Without complications
0.000 0.066 0.934
E10.4 With neurological complications
0.000 0.078 0.922
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.163 0.837
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.168 0.832
E16 Other disorders of pancreatic internal secretion
0.000 0.171 0.829
E16.2 Hypoglycaemia, unspecified
0.000 0.176 0.824
E10.6 With other specified complications
0.000 0.180 0.820
E10.0 With coma
0.000 0.213 0.787
E10.5 With peripheral circulatory complications
0.000 0.227 0.773
E20-E35 Disorders of other endocrine glands
0.000 0.269 0.731
E10.7 With multiple complications
0.000 0.283 0.717
E16.1 Other hypoglycaemia
0.000 0.284 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.301 0.699
E14 Unspecified diabetes mellitus
0.000 0.307 0.693
E23 Hypofunction and other disorders of pituitary gland
0.000 0.307 0.693
E13.8 With unspecified complications
0.000 0.318 0.682
E13.7 With multiple complications
0.000 0.318 0.682
E13.6 With other specified complications
0.000 0.318 0.682
E13.5 With peripheral circulatory complications
0.000 0.318 0.682
E13.4 With neurological complications
0.000 0.318 0.682
E13.3 With ophthalmic complications
0.000 0.318 0.682
E13.2 With renal complications
0.000 0.318 0.682
E13.1 With ketoacidosis
0.000 0.318 0.682
E13.0 With coma
0.000 0.318 0.682
E10.8 With unspecified complications
0.000 0.335 0.665
E23.0 Hypopituitarism
0.000 0.347 0.653
E50-E64 Other nutritional deficiencies
0.000 0.385 0.615
E24 Cushing's syndrome
0.000 0.399 0.601
E15 Nondiabetic hypoglycaemic coma
0.000 0.403 0.597
E23.2 Diabetes insipidus
0.000 0.404 0.596
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.405 0.595
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.405 0.595
E16.4 Abnormal secretion of gastrin
0.000 0.405 0.595
E16.3 Increased secretion of glucagon
0.000 0.405 0.595
E00-E07 Disorders of thyroid gland
0.000 0.407 0.593
E20 Hypoparathyroidism
0.000 0.412 0.588
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.425 0.575
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.425 0.575
E22 Hyperfunction of pituitary gland
0.000 0.427 0.573
E11 Non-insulin-dependent diabetes mellitus
0.000 0.432 0.568
E29 Testicular dysfunction
0.000 0.440 0.560
E40-E46 Malnutrition
0.000 0.444 0.556
E05.9 Thyrotoxicosis, unspecified
0.000 0.450 0.550
E14.2 Withrenal complications
0.000 0.472 0.528
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.476 0.524
E32 Diseases of thymus
0.000 0.476 0.524
E30 Disorders of puberty, not elsewhere classified
0.000 0.476 0.524
E25 Adrenogenital disorders
0.000 0.476 0.524
E14.4 With neurological complications
0.000 0.477 0.523
E14.8 With unspecified complications
0.000 0.490 0.509
E23.7 Disorder of pituitary gland, unspecified
0.000 0.491 0.509
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.497 0.503
E11.2 With renal complications
0.000 0.498 0.502
E12.9 Without complications
0.000 0.499 0.501
E12.8 With unspecified complications
0.000 0.499 0.501
E12.7 With multiple complications
0.000 0.499 0.501
E12.6 With other specified complications
0.000 0.499 0.501
E12.5 With peripheral circulatory complications
0.000 0.499 0.501
E12.4 With neurological complications
0.000 0.499 0.501
E12.3 With ophthalmic complications
0.000 0.499 0.501
E12.2 With renal complications
0.000 0.499 0.501
E12.1 With ketoacidosis
0.000 0.499 0.501
E12.0 With coma
0.000 0.499 0.501
E28 Ovarian dysfunction
0.000 0.499 0.501
E05.8 Other thyrotoxicosis
0.000 0.500 0.500
E14.1 With ketoacidosis
0.000 0.500 0.500
E14.7 With multiple complications
0.000 0.503 0.497
E14.6 With other specified complications
0.000 0.503 0.497
E14.5 With peripheral circulatory complications
0.000 0.503 0.497
E14.0 With coma
0.000 0.503 0.497
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.503 0.497
E23.1 Drug-induced hypopituitarism
0.000 0.503 0.497
E24.9 Cushing's syndrome, unspecified
0.000 0.505 0.495
E55 Vitamin D deficiency
0.000 0.505 0.495
E20.9 Hypoparathyroidism, unspecified
0.000 0.515 0.485
E11.6 With other specified complications
0.000 0.515 0.485
E27 Other disorders of adrenal gland
0.000 0.521 0.479
E14.3 With ophthalmic complications
0.000 0.525 0.475
E51 Thiamine deficiency
0.000 0.526 0.474
E31 Polyglandular dysfunction
0.000 0.527 0.472
E22.0 Acromegaly and pituitary gigantism
0.000 0.535 0.465
E11.0 With coma
0.000 0.540 0.460
E56 Other vitamin deficiencies
0.000 0.548 0.452
E24.2 Drug-induced Cushing's syndrome
0.000 0.549 0.451
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.556 0.444
E53 Deficiency of other B group vitamins
0.000 0.557 0.443
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.559 0.441
E63 Other nutritional deficiencies
0.000 0.559 0.441
E50 Vitamin A deficiency
0.000 0.559 0.441
E60 Dietary zinc deficiency
0.000 0.559 0.441
E59 Dietary selenium deficiency
0.000 0.559 0.441
E54 Ascorbic acid deficiency
0.000 0.559 0.441
E52 Niacin deficiency [pellagra]
0.000 0.559 0.441
E34 Other endocrine disorders
0.000 0.559 0.441
E29.1 Testicular hypofunction
0.000 0.562 0.438
E24.8 Other Cushing's syndrome
0.000 0.569 0.431
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.569 0.431
E24.3 Ectopic ACTH syndrome
0.000 0.569 0.431
E24.1 Nelson's syndrome
0.000 0.569 0.431
E24.0 Pituitary-dependent Cushing's disease
0.000 0.569 0.431
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.575 0.425
E00 Congenital iodine-deficiency syndrome
0.000 0.575 0.425
E11.1 With ketoacidosis
0.000 0.575 0.425
E26 Hyperaldosteronism
0.000 0.576 0.424
E14.9 Without complications
0.000 0.576 0.424
E20.8 Other hypoparathyroidism
0.000 0.578 0.422
E20.1 Pseudohypoparathyroidism
0.000 0.578 0.422
E20.0 Idiopathic hypoparathyroidism
0.000 0.578 0.422
E22.1 Hyperprolactinaemia
0.000 0.587 0.413
E05.5 Thyroid crisis or storm
0.000 0.588 0.412
E05.4 Thyrotoxicosis factitia
0.000 0.588 0.412
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.588 0.412
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.589 0.411
E22.8 Other hyperfunction of pituitary gland
0.000 0.589 0.411
E55.9 Vitamin D deficiency, unspecified
0.000 0.590 0.409
E11.7 With multiple complications
0.000 0.593 0.407
E27.1 Primary adrenocortical insufficiency
0.000 0.593 0.407
E29.9 Testicular dysfunction, unspecified
0.000 0.598 0.402
E29.8 Other testicular dysfunction
0.000 0.598 0.402
E29.0 Testicular hyperfunction
0.000 0.598 0.402
E11.8 With unspecified complications
0.000 0.598 0.401
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.599 0.401
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.601 0.399
E45 Retarded development following protein-energy malnutrition
0.000 0.601 0.399
E43 Unspecified severe protein-energy malnutrition
0.000 0.601 0.399
E42 Marasmic kwashiorkor
0.000 0.601 0.399
E41 Nutritional marasmus
0.000 0.601 0.399
E40 Kwashiorkor
0.000 0.601 0.399
E23.6 Other disorders of pituitary gland
0.000 0.603 0.397
E53.9 Vitamin B deficiency, unspecified
0.000 0.607 0.393
E07 Other disorders of thyroid
0.000 0.607 0.393
E61 Deficiency of other nutrient elements
0.000 0.615 0.385
E28.3 Primary ovarian failure
0.000 0.616 0.384
E58 Dietary calcium deficiency
0.000 0.616 0.384
E25.9 Adrenogenital disorder, unspecified
0.000 0.624 0.376
E25.8 Other adrenogenital disorders
0.000 0.624 0.376
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.624 0.376
E30.9 Disorder of puberty, unspecified
0.000 0.624 0.376
E30.8 Other disorders of puberty
0.000 0.624 0.376
E30.1 Precocious puberty
0.000 0.624 0.376
E30.0 Delayed puberty
0.000 0.624 0.376
E32.9 Disease of thymus, unspecified
0.000 0.624 0.376
E32.8 Other diseases of thymus
0.000 0.624 0.376
E32.1 Abscess of thymus
0.000 0.624 0.376
E32.0 Persistent hyperplasia of thymus
0.000 0.624 0.376
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.624 0.376
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.624 0.376
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.624 0.376
E11.5 With peripheral circulatory complications
0.000 0.624 0.376
E51.2 Wernicke's encephalopathy
0.000 0.628 0.372
E28.9 Ovarian dysfunction, unspecified
0.000 0.641 0.359
E28.8 Other ovarian dysfunction
0.000 0.641 0.359
E28.1 Androgen excess
0.000 0.641 0.359
E28.0 Oestrogen excess
0.000 0.641 0.359
E55.0 Rickets, active
0.000 0.645 0.355
E46 Unspecified protein-energy malnutrition
0.000 0.645 0.354
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.653 0.346
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.654 0.346
E27.5 Adrenomedullary hyperfunction
0.000 0.657 0.343
E27.0 Other adrenocortical overactivity
0.000 0.657 0.343
E51.9 Thiamine deficiency, unspecified
0.000 0.660 0.340
E51.8 Other manifestations of thiamine deficiency
0.000 0.660 0.340
E51.1 Beriberi
0.000 0.660 0.340
E27.8 Other specified disorders of adrenal gland
0.000 0.660 0.340
E31.9 Polyglandular dysfunction, unspecified
0.000 0.661 0.339
E31.8 Other polyglandular dysfunction
0.000 0.661 0.339
E31.1 Polyglandular hyperfunction
0.000 0.661 0.339
E56.1 Deficiency of vitamin K
0.000 0.664 0.335
E11.4 With neurological complications
0.000 0.667 0.333
K90 Intestinal malabsorption
0.000 0.669 0.331
E34.8 Other specified endocrine disorders
0.000 0.672 0.328
E06 Thyroiditis
0.000 0.674 0.326
E56.9 Vitamin deficiency, unspecified
0.000 0.676 0.324
E56.8 Deficiency of other vitamins
0.000 0.676 0.324
E56.0 Deficiency of vitamin E
0.000 0.676 0.324
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.677 0.323
E53.1 Pyridoxine deficiency
0.000 0.682 0.317
E53.0 Riboflavin deficiency
0.000 0.682 0.317
E50.9 Vitamin A deficiency, unspecified
0.000 0.683 0.316
E50.8 Other manifestations of vitamin A deficiency
0.000 0.683 0.316
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.683 0.316
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.683 0.316
E50.5 Vitamin A deficiency with night blindness
0.000 0.683 0.316
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.683 0.316
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.683 0.316
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.683 0.316
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.683 0.316
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.683 0.316
E63.9 Nutritional deficiency, unspecified
0.000 0.683 0.316
E63.8 Other specified nutritional deficiencies
0.000 0.683 0.316
E63.1 Imbalance of constituents of food intake
0.000 0.683 0.316
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.683 0.316
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.683 0.316
E64.8 Sequelae of other nutritional deficiencies
0.000 0.683 0.316
E64.3 Sequelae of rickets
0.000 0.683 0.316
E64.2 Sequelae of vitamin C deficiency
0.000 0.683 0.316
E64.1 Sequelae of vitamin A deficiency
0.000 0.683 0.316
E64.0 Sequelae of protein-energy malnutrition
0.000 0.683 0.316
E34.5 Androgen resistance syndrome
0.000 0.684 0.316
E34.4 Constitutional tall stature
0.000 0.684 0.316
E34.3 Short stature, not elsewhere classified
0.000 0.684 0.316
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.684 0.316
E34.1 Other hypersecretion of intestinal hormones
0.000 0.684 0.316
E27.9 Disorder of adrenal gland, unspecified
0.000 0.685 0.315
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.691 0.309
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.695 0.305
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.695 0.305
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.695 0.305
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.695 0.305
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.695 0.305
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.695 0.305
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.695 0.305
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.695 0.305
E26.9 Hyperaldosteronism, unspecified
0.000 0.696 0.304
E26.8 Other hyperaldosteronism
0.000 0.696 0.304
E26.1 Secondary hyperaldosteronism
0.000 0.696 0.304
E28.2 Polycystic ovarian syndrome
0.000 0.699 0.301
E34.9 Endocrine disorder, unspecified
0.000 0.702 0.298
E07.8 Other specified disorders of thyroid
0.000 0.702 0.298
E83 Disorders of mineral metabolism
0.293 0.707 0.000
E31.0 Autoimmune polyglandular failure
0.000 0.713 0.287
E44.1 Mild protein-energy malnutrition
0.000 0.714 0.286
E44.0 Moderate protein-energy malnutrition
0.000 0.714 0.286
E07.1 Dyshormogenetic goitre
0.000 0.718 0.282
E07.0 Hypersecretion of calcitonin
0.000 0.718 0.282
E61.9 Deficiency of nutrient element, unspecified
0.000 0.724 0.276
E61.8 Deficiency of other specified nutrient elements
0.000 0.724 0.276
E61.7 Deficiency of multiple nutrient elements
0.000 0.724 0.276
E61.6 Vanadium deficiency
0.000 0.724 0.276
E61.5 Molybdenum deficiency
0.000 0.724 0.276
E61.4 Chromium deficiency
0.000 0.724 0.276
E61.3 Manganese deficiency
0.000 0.724 0.276
E61.0 Copper deficiency
0.000 0.724 0.276
E03 Other hypothyroidism
0.000 0.724 0.276
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.729 0.271
E65-E68 Obesity and other hyperalimentation
0.000 0.730 0.270
E06.9 Thyroiditis, unspecified
0.000 0.735 0.265
E61.1 Iron deficiency
0.000 0.748 0.252
E61.2 Magnesium deficiency
0.000 0.750 0.249
E34.0 Carcinoid syndrome
0.000 0.760 0.240
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.762 0.238
E83.3 Disorders of phosphorus metabolism
0.238 0.762 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.762 0.237
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.762 0.237
K90.1 Tropical sprue
0.000 0.762 0.237
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.763 0.236
E27.2 Addisonian crisis
0.000 0.765 0.234
E06.4 Drug-induced thyroiditis
0.000 0.766 0.234
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.766 0.234
E06.1 Subacute thyroiditis
0.000 0.766 0.234
E06.0 Acute thyroiditis
0.000 0.766 0.234
E07.9 Disorder of thyroid, unspecified
0.000 0.776 0.224
E21.4 Other specified disorders of parathyroid gland
0.000 0.778 0.222
E21.2 Other hyperparathyroidism
0.000 0.778 0.222
K90.8 Other intestinal malabsorption
0.000 0.779 0.221
E03.8 Other specified hypothyroidism
0.000 0.780 0.220
E83.9 Disorder of mineral metabolism, unspecified
0.210 0.790 0.000
E83.8 Other disorders of mineral metabolism
0.210 0.790 0.000
E83.2 Disorders of zinc metabolism
0.210 0.790 0.000
E83.0 Disorders of copper metabolism
0.210 0.790 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.790 0.210
E21.3 Hyperparathyroidism, unspecified
0.000 0.794 0.206
E26.0 Primary hyperaldosteronism
0.001 0.796 0.204
E83.4 Disorders of magnesium metabolism
0.202 0.797 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.801 0.199
E03.5 Myxoedema coma
0.000 0.802 0.198
E03.4 Atrophy of thyroid (acquired)
0.000 0.802 0.198
E03.3 Postinfectious hypothyroidism
0.000 0.802 0.198
E03.1 Congenital hypothyroidism without goitre
0.000 0.802 0.198
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.802 0.198
E67 Other hyperalimentation
0.000 0.806 0.194
E68 Sequelae of hyperalimentation
0.000 0.806 0.194
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.813 0.187
E06.5 Other chronic thyroiditis
0.000 0.817 0.183
E11.3 With ophthalmic complications
0.000 0.845 0.155
E65 Localised adiposity
0.000 0.858 0.142
E06.3 Autoimmune thyroiditis
0.000 0.859 0.140
E67.8 Other specified hyperalimentation
0.000 0.861 0.139
E67.3 Hypervitaminosis D
0.000 0.861 0.139
E67.2 Megavitamin-B6 syndrome
0.000 0.861 0.139
E67.1 Hypercarotenaemia
0.000 0.861 0.139
E67.0 Hypervitaminosis A
0.000 0.861 0.139
E53.8 Deficiency of other specified B group vitamins
0.000 0.871 0.129
E04 Other non-toxic goitre
0.000 0.890 0.110
E04.9 Non-toxic goitre, unspecified
0.000 0.908 0.092
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.092 0.908 0.000
E83.5 Disorders of calcium metabolism
0.090 0.910 0.000
E04.8 Other specified non-toxic goitre
0.000 0.921 0.079
E11.9 Without complications
0.000 0.924 0.076
E21.0 Primary hyperparathyroidism
0.000 0.939 0.061
E04.0 Non-toxic diffuse goitre
0.001 0.952 0.047
I83 Varicose veins of lower extremities
0.042 0.958 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.033 0.967 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.032 0.968 0.000
E66 Obesity
0.000 0.972 0.027
K51 Ulcerative colitis
0.026 0.974 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.026 0.974 0.000
K51.4 Pseudopolyposis of colon
0.025 0.975 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.025 0.975 0.000
K51.2 Ulcerative (chronic) proctitis
0.024 0.976 0.000
K51.9 Ulcerative colitis, unspecified
0.023 0.977 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.022 0.978 0.000
K51.5 Mucosal proctocolitis
0.021 0.979 0.000
A08.4 Viral intestinal infection, unspecified
0.000 0.980 0.020
V18.0 Driver injured in nontraffic accident
0.020 0.980 0.000
E66.1 Drug-induced obesity
0.000 0.980 0.020
K90-K93 Other diseases of the digestive system
0.000 0.981 0.019
K51.1 Ulcerative (chronic) ileocolitis
0.019 0.981 0.000
E66.0 Obesity due to excess calories
0.000 0.983 0.016
K51.8 Other ulcerative colitis
0.016 0.984 0.000
E04.1 Non-toxic single thyroid nodule
0.001 0.984 0.015
F45.8 Other somatoform disorders
0.000 0.985 0.015
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.985 0.014
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.986 0.014
M79.09 Rheumatism, unspecified (Site unspecified)
0.000 0.988 0.012
V18 Pedal cyclist injured in noncollision transport accident
0.011 0.989 0.000
N18.4 Chronic kidney disease, stage 4
0.000 0.989 0.011
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.990 0.010
K93.1 Megacolon in Chagas' disease
0.000 0.990 0.010
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.990 0.010
E70-E90 Metabolic disorders
0.004 0.990 0.007
J38.7 Other diseases of larynx
0.010 0.990 0.000
H54.0 Blindness, both eyes
0.000 0.991 0.009
E04.2 Non-toxic multinodular goitre
0.001 0.991 0.008
F45 Somatoform disorders
0.000 0.991 0.009
J38.4 Oedema of larynx
0.009 0.991 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.009 0.991 0.000
V18.5 Passenger injured in traffic accident
0.009 0.991 0.000
V18.9 Unspecified pedal cyclist injured in traffic accident
0.008 0.992 0.000
V18.4 Driver injured in traffic accident
0.008 0.992 0.000
V18.1 Passenger injured in nontraffic accident
0.008 0.992 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.008 0.992 0.000
H54 Blindness and low vision
0.000 0.992 0.008
H54.9 Unspecified visual impairment (binocular)
0.000 0.992 0.008
V18.2 Unspecified pedal cyclist injured in nontraffic accident
0.008 0.992 0.000
E73 Lactose intolerance
0.002 0.992 0.006
J38.3 Other diseases of vocal cords
0.008 0.992 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.000 0.992 0.008
E79 Disorders of purine and pyrimidine metabolism
0.003 0.992 0.005
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.003 0.992 0.005
E74 Other disorders of carbohydrate metabolism
0.002 0.992 0.006
N18.5 Chronic kidney disease, stage 5
0.000 0.992 0.008
E77 Disorders of glycoprotein metabolism
0.003 0.992 0.005
E76 Disorders of glycosaminoglycan metabolism
0.003 0.992 0.005
E72 Other disorders of amino-acid metabolism
0.003 0.992 0.005
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.003 0.992 0.005
E70 Disorders of aromatic amino-acid metabolism
0.003 0.992 0.005
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.003 0.992 0.005
V18.3 Person injured while boarding or alighting
0.008 0.992 0.000
E84 Cystic fibrosis
0.003 0.992 0.005
F45.9 Somatoform disorder, unspecified
0.000 0.993 0.007
M79.0 Rheumatism, unspecified
0.000 0.993 0.007
E66.8 Other obesity
0.000 0.993 0.007
C43.5 Malignant melanoma of trunk
0.000 0.993 0.007
H54.6 Unqualified visual loss, one eye
0.000 0.993 0.007
D47.4 Osteomyelofibrosis
0.000 0.993 0.007
F45.0 Somatisation disorder
0.000 0.993 0.007
S42.10 Fracture of scapula (closed)
0.000 0.993 0.007
M79.08 Rheumatism, unspecified (Other)
0.000 0.993 0.007
N08.3 Glomerular disorders in diabetes mellitus
0.000 0.993 0.007
D47.2 Monoclonal gammopathy
0.000 0.993 0.007
E85 Amyloidosis
0.002 0.993 0.005
S62.30 Fracture of other metacarpal bone (closed)
0.000 0.993 0.007
J35.8 Other chronic diseases of tonsils and adenoids
0.007 0.993 0.000
K50-K52 Noninfective enteritis and colitis
0.007 0.993 0.000
A08 Viral and other specified intestinal infections
0.000 0.993 0.007
F45.2 Hypochondriacal disorder
0.000 0.993 0.007
N18 Chronic renal failure
0.000 0.993 0.007
J38.2 Nodules of vocal cords
0.007 0.993 0.000
H54.5 Low vision, one eye
0.000 0.993 0.007
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.993 0.007
F45.1 Undifferentiated somatoform disorder
0.000 0.993 0.007
F45.3 Somatoform autonomic dysfunction
0.000 0.993 0.007
J38.5 Laryngeal spasm
0.007 0.993 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.000 0.993 0.007
F45.4 Persistent somatoform pain disorder
0.000 0.993 0.006
H54.7 Unspecified visual loss
0.000 0.994 0.006
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity
0.006 0.994 0.000
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity
0.006 0.994 0.000
E73.9 Lactose intolerance, unspecified
0.001 0.994 0.005
N18.0 End-stage renal disease
0.000 0.994 0.006
H54.3 Unqualified visual loss, both eyes
0.000 0.994 0.006
E73.8 Other lactose intolerance
0.002 0.994 0.004
E73.1 Secondary lactase deficiency
0.002 0.994 0.004
E73.0 Congenital lactase deficiency
0.002 0.994 0.004
K50 Crohn's disease [regional enteritis]
0.006 0.994 0.000
E75.5 Other lipid storage disorders
0.002 0.994 0.004
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.002 0.994 0.004
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.994 0.005
E75.6 Lipid storage disorder, unspecified
0.002 0.994 0.004
E75.4 Neuronal ceroid lipofuscinosis
0.002 0.994 0.004
E75.3 Sphingolipidosis, unspecified
0.002 0.994 0.004
E75.2 Other sphingolipidosis
0.002 0.994 0.004
E75.1 Other gangliosidosis
0.002 0.994 0.004
E75.0 GM2 gangliosidosis
0.002 0.994 0.004
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.002 0.994 0.004
E79.8 Other disorders of purine and pyrimidine metabolism
0.002 0.994 0.004
E79.1 Lesch-Nyhan syndrome
0.002 0.994 0.004
E74.9 Disorder of carbohydrate metabolism, unspecified
0.002 0.994 0.004
E74.8 Other specified disorders of carbohydrate metabolism
0.002 0.994 0.004
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.002 0.994 0.004
E74.2 Disorders of galactose metabolism
0.002 0.994 0.004
E74.1 Disorders of fructose metabolism
0.002 0.994 0.004
E74.0 Glycogen storage disease
0.002 0.994 0.004
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.002 0.994 0.004
E70.8 Other disorders of aromatic amino-acid metabolism
0.002 0.994 0.004
E70.3 Albinism
0.002 0.994 0.004
E70.2 Disorders of tyrosine metabolism
0.002 0.994 0.004
E70.1 Other hyperphenylalaninaemias
0.002 0.994 0.004
E70.0 Classical phenylketonuria
0.002 0.994 0.004
E71.3 Disorders of fatty-acid metabolism
0.002 0.994 0.004
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.002 0.994 0.004
E71.1 Other disorders of branched-chain amino-acid metabolism
0.002 0.994 0.004
E71.0 Maple-syrup-urine disease
0.002 0.994 0.004
E72.9 Disorder of amino-acid metabolism, unspecified
0.002 0.994 0.004
E72.8 Other specified disorders of amino-acid metabolism
0.002 0.994 0.004
E72.5 Disorders of glycine metabolism
0.002 0.994 0.004
E72.4 Disorders of ornithine metabolism
0.002 0.994 0.004
E72.3 Disorders of lysine and hydroxylysine metabolism
0.002 0.994 0.004
E72.2 Disorders of urea cycle metabolism
0.002 0.994 0.004
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.002 0.994 0.004
E72.0 Disorders of amino-acid transport
0.002 0.994 0.004
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.002 0.994 0.004
E76.8 Other disorders of glucosaminoglycan metabolism
0.002 0.994 0.004
E76.3 Mucopolysaccharidosis, unspecified
0.002 0.994 0.004
E76.2 Other mucopolysaccharidoses
0.002 0.994 0.004
E76.1 Mucopolysaccharidosis, type II
0.002 0.994 0.004
E76.0 Mucopolysaccharidosis, type I
0.002 0.994 0.004
E77.9 Disorder of glycoprotein metabolism, unspecified
0.002 0.994 0.004
E77.8 Other disorders of glycoprotein metabolism
0.002 0.994 0.004
E77.1 Defects in glycoprotein degradation
0.002 0.994 0.004
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.002 0.994 0.004
M79.01 Rheumatism, unspecified (Shoulder region)
0.000 0.994 0.006
V10-V19 Pedal cyclist injured in transport accident
0.006 0.994 0.000
H54.2 Low vision, both eyes
0.000 0.994 0.006
E88 Other metabolic disorders
0.002 0.994 0.003
E84.8 Cystic fibrosis with other manifestations
0.002 0.994 0.004
E84.1 Cystic fibrosis with intestinal manifestations
0.002 0.994 0.004
E84.0 Cystic fibrosis with pulmonary manifestations
0.002 0.994 0.004
J38.1 Polyp of vocal cord and larynx
0.006 0.994 0.000
F41.1 Generalised anxiety disorder
0.000 0.994 0.006
M79.00 Rheumatism, unspecified (Multiple sites)
0.000 0.994 0.006
K04.5 Chronic apical periodontitis
0.006 0.994 0.000
M79.07 Rheumatism, unspecified (Ankle and foot)
0.000 0.994 0.005
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.000 0.994 0.005
M79.04 Rheumatism, unspecified (Hand)
0.000 0.994 0.005
M79.03 Rheumatism, unspecified (Forearm)
0.000 0.994 0.005
M79.02 Rheumatism, unspecified (Upper arm)
0.000 0.994 0.005
E84.9 Cystic fibrosis, unspecified
0.002 0.995 0.003
A08.3 Other viral enteritis
0.000 0.995 0.005
J38.6 Stenosis of larynx
0.005 0.995 0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.995 0.005
E80 Disorders of porphyrin and bilirubin metabolism
0.003 0.995 0.002
E85.8 Other amyloidosis
0.002 0.995 0.004
E85.2 Heredofamilial amyloidosis, unspecified
0.002 0.995 0.004
E85.1 Neuropathic heredofamilial amyloidosis
0.002 0.995 0.004
E85.0 Nonneuropathic heredofamilial amyloidosis
0.002 0.995 0.004
L43.9 Lichen planus, unspecified
0.000 0.995 0.005
H54.1 Blindness, one eye, low vision, other eye
0.000 0.995 0.005
A08.5 Other specified intestinal infections
0.000 0.995 0.005
A08.2 Adenoviral enteritis
0.000 0.995 0.005
A08.0 Rotaviral enteritis
0.000 0.995 0.005
H54.4 Blindness, one eye
0.000 0.995 0.005
E85.4 Organ-limited amyloidosis
0.001 0.995 0.004
E85.3 Secondary systemic amyloidosis
0.001 0.995 0.004
K50.9 Crohn's disease, unspecified
0.005 0.995 0.000
N18.1 Chronic kidney disease, stage 1
0.000 0.995 0.005
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.995 0.005
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.000 0.995 0.005
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.000 0.995 0.005
K50.0 Crohn's disease of small intestine
0.005 0.995 0.000
N18.9 Chronic renal failure, unspecified
0.000 0.995 0.005
V19 Pedal cyclist injured in other and unspecified transport accidents
0.005 0.995 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.000 0.995 0.005
E85.9 Amyloidosis, unspecified
0.002 0.995 0.003
N08.5 Glomerular disorders in systemic connective tissue disorders
0.000 0.995 0.005
V10 Pedal cyclist injured in collision with pedestrian or animal
0.005 0.995 0.000
V17 Pedal cyclist injured in collision with fixed or stationary object
0.005 0.995 0.000
M79.06 Rheumatism, unspecified (Lower leg)
0.000 0.995 0.004
N18.2 Chronic kidney disease, stage 2
0.000 0.995 0.005
N48.4 Impotence of organic origin
0.005 0.995 0.000
K50.1 Crohn's disease of large intestine
0.004 0.996 0.000
V16 Pedal cyclist injured in collision with other nonmotor vehicle
0.004 0.996 0.000
V15 Pedal cyclist injured in collision with railway train or railway vehicle
0.004 0.996 0.000
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus
0.004 0.996 0.000
V13 Pedal cyclist injured in collision with car, pick-up truck or van
0.004 0.996 0.000
V12 Pedal cyclist injured in collision with two- or three-wheeled motor vehicle
0.004 0.996 0.000
E88.9 Metabolic disorder, unspecified
0.002 0.996 0.003
V19.3 Pedal cyclist [any] injured in an unspecified nontraffic accident
0.004 0.996 0.000
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.996 0.003
N18.8 Other chronic renal failure
0.000 0.996 0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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