TreeWAS – Variant ID: rs142453246

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z60.2 Living alone	0.040	0.960	0.000
Z60 Problems related to social environment	0.023	0.976	0.000
Z60.9 Problem related to social environment, unspecified	0.017	0.983	0.000
Z60.8 Other problems related to social environment	0.017	0.983	0.000
Z60.5 Target of perceived adverse discrimination and persecution	0.017	0.983	0.000
Z60.4 Social exclusion and rejection	0.017	0.983	0.000
Z60.3 Acculturation difficulty	0.017	0.983	0.000
Z60.1 Atypical parenting situation	0.017	0.983	0.000
Z60.0 Problems of adjustment to life-cycle transitions	0.017	0.983	0.000
Z03.8 Observation for other suspected diseases and conditions	0.013	0.987	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.011	0.989	0.000
Z63 Other problems related to primary support group, including family circumstances	0.009	0.991	0.000
Z65 Problems related to other psychosocial circumstances	0.008	0.992	0.000
Z64 Problems related to certain psychosocial circumstances	0.008	0.992	0.000
Z62 Other problems related to upbringing	0.008	0.992	0.000
Z61 Problems related to negative life events in childhood	0.008	0.992	0.000
Z59 Problems related to housing and economic circumstances	0.008	0.992	0.000
Z58 Problems related to physical environment	0.008	0.992	0.000
Z56 Problems related to employment and unemployment	0.008	0.992	0.000
Z55 Problems related to education and literacy	0.008	0.992	0.000
Z57 Occupational exposure to risk-factors	0.008	0.992	0.000
Z63.4 Disappearance and death of family member	0.007	0.993	0.000
Z63.9 Problem related to primary support group, unspecified	0.006	0.993	0.000
Z63.8 Other specified problems related to primary support group	0.006	0.993	0.000
Z63.7 Other stressful life events affecting family and household	0.006	0.993	0.000
Z63.6 Dependent relative needing care at home	0.006	0.993	0.000
Z63.5 Disruption of family by separation and divorce	0.006	0.993	0.000
Z63.3 Absence of family member	0.006	0.993	0.000
Z63.2 Inadequate family support	0.006	0.993	0.000
Z63.1 Problems in relationship with parents and in-laws	0.006	0.993	0.000
Z63.0 Problems in relationship with spouse or partner	0.006	0.993	0.000
Z55.9 Problems relating to education and literacy, unspecified	0.006	0.994	0.000
Z55.8 Other problems relating to education and literacy	0.006	0.994	0.000
Z55.4 Educational maladjustment and discord with teachers and classmates	0.006	0.994	0.000
Z55.3 Underachievement in school	0.006	0.994	0.000
Z55.2 Failed examinations	0.006	0.994	0.000
Z55.1 Schooling unavailable and unattainable	0.006	0.994	0.000
Z55.0 Illiteracy and low-level literacy	0.006	0.994	0.000
Z56.7 Other and unspecified problems related to employment	0.006	0.994	0.000
Z56.6 Other physical and mental strain related to work	0.006	0.994	0.000
Z56.5 Uncongenial work	0.006	0.994	0.000
Z56.4 Discord with boss and workmates	0.006	0.994	0.000
Z56.3 Stressful work schedule	0.006	0.994	0.000
Z56.2 Threat of job loss	0.006	0.994	0.000
Z56.1 Change of job	0.006	0.994	0.000
Z56.0 Unemployment, unspecified	0.006	0.994	0.000
Z58.9 Problem related to physical environment, unspecified	0.006	0.994	0.000
Z58.8 Other problems related to physical environment	0.006	0.994	0.000
Z58.7 Exposure to tobacco smoke	0.006	0.994	0.000
Z58.6 Inadequate drinking-water supply	0.006	0.994	0.000
Z58.5 Exposure to other pollution	0.006	0.994	0.000
Z58.4 Exposure to radiation	0.006	0.994	0.000
Z58.3 Exposure to soil pollution	0.006	0.994	0.000
Z58.2 Exposure to water pollution	0.006	0.994	0.000
Z58.1 Exposure to air pollution	0.006	0.994	0.000
Z58.0 Exposure to noise	0.006	0.994	0.000
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.006	0.994	0.000
Z59.8 Other problems relating to housing and economic circumstances	0.006	0.994	0.000
Z59.7 Insufficient social insurance and welfare support	0.006	0.994	0.000
Z59.6 Low income	0.006	0.994	0.000
Z59.5 Extreme poverty	0.006	0.994	0.000
Z59.4 Lack of adequate food	0.006	0.994	0.000
Z59.3 Problems related to living in residential institution	0.006	0.994	0.000
Z59.2 Discord with neighbours, lodgers and landlord	0.006	0.994	0.000
Z59.1 Inadequate housing	0.006	0.994	0.000
Z59.0 Homelessness	0.006	0.994	0.000
Z61.9 Negative life events in childhood, unspecified	0.006	0.994	0.000
Z61.8 Other negative life events in childhood	0.006	0.994	0.000
Z61.7 Personal frightening experience in childhood	0.006	0.994	0.000
Z61.6 Problems related to alleged physical abuse of child	0.006	0.994	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.006	0.994	0.000
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.006	0.994	0.000
Z61.3 Events resulting in loss of self-esteem in childhood	0.006	0.994	0.000
Z61.2 Altered pattern of family relationships in childhood	0.006	0.994	0.000
Z61.1 Removal from home in childhood	0.006	0.994	0.000
Z61.0 Loss of love relationship in childhood	0.006	0.994	0.000
Z62.9 Problem related to upbringing, unspecified	0.006	0.994	0.000
Z62.8 Other specified problems related to upbringing	0.006	0.994	0.000
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.006	0.994	0.000
Z62.5 Other problems related to neglect in upbringing	0.006	0.994	0.000
Z62.4 Emotional neglect of child	0.006	0.994	0.000
Z62.3 Hostility towards and scapegoating of child	0.006	0.994	0.000
Z62.2 Institutional upbringing	0.006	0.994	0.000
Z62.1 Parental overprotection	0.006	0.994	0.000
Z62.0 Inadequate parental supervision and control	0.006	0.994	0.000
Z64.4 Discord with counsellors	0.006	0.994	0.000
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.006	0.994	0.000
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.006	0.994	0.000
Z64.1 Problems related to multiparity	0.006	0.994	0.000
Z64.0 Problems related to unwanted pregnancy	0.006	0.994	0.000
Z65.9 Problem related to unspecified psychosocial circumstances	0.006	0.994	0.000
Z65.8 Other specified problems related to psychosocial circumstances	0.006	0.994	0.000
Z65.5 Exposure to disaster, war and other hostilities	0.006	0.994	0.000
Z65.4 Victim of crime and terrorism	0.006	0.994	0.000
Z65.3 Problems related to other legal circumstances	0.006	0.994	0.000
Z65.2 Problems related to release from prison	0.006	0.994	0.000
Z65.1 Imprisonment and other incarceration	0.006	0.994	0.000
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.006	0.994	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.006	0.994	0.000
Z57.8 Occupational exposure to other risk-factors	0.006	0.994	0.000
Z57.7 Occupational exposure to vibration	0.006	0.994	0.000
Z57.6 Occupational exposure to extreme temperature	0.006	0.994	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.006	0.994	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.006	0.994	0.000
Z57.3 Occupational exposure to other air contaminants	0.006	0.994	0.000
Z57.1 Occupational exposure to radiation	0.006	0.994	0.000
Z57.0 Occupational exposure to noise	0.006	0.994	0.000
Z57.2 Occupational exposure to dust	0.005	0.994	0.000
K76 Other diseases of liver	0.005	0.995	0.000
I67.9 Cerebrovascular disease, unspecified	0.005	0.995	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.005	0.995	0.000
K76.8 Other specified diseases of liver	0.005	0.995	0.000
K76.6 Portal hypertension	0.005	0.995	0.000
K76.9 Liver disease, unspecified	0.004	0.995	0.000
Z03 Medical observation and evaluation for suspected diseases and conditions	0.004	0.995	0.000
K76.7 Hepatorenal syndrome	0.004	0.996	0.000
K76.5 Hepatic veno-occlusive disease	0.004	0.996	0.000
K76.4 Peliosis hepatis	0.004	0.996	0.000
K76.3 Infarction of liver	0.004	0.996	0.000
K76.2 Central haemorrhagic necrosis of liver	0.004	0.996	0.000
K76.1 Chronic passive congestion of liver	0.004	0.996	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.004	0.996	0.000
Z03.9 Observation for suspected disease or condition, unspecified	0.004	0.996	0.000
K74 Fibrosis and cirrhosis of liver	0.004	0.996	0.000
K70-K77 Diseases of liver	0.004	0.996	0.000
M54.22 Cervicalgia (Cervical region)	0.004	0.996	0.000
K74.6 Other and unspecified cirrhosis of liver	0.004	0.996	0.000
Z03.5 Observation for other suspected cardiovascular diseases	0.004	0.996	0.000
K74.3 Primary biliary cirrhosis	0.004	0.996	0.000
M54.59 Low back pain (Site unspecified)	0.004	0.996	0.000
Z03.6 Observation for suspected toxic effect from ingested substance	0.003	0.996	0.000
Z03.2 Observation for suspected mental and behavioural disorders	0.003	0.996	0.000
Z03.0 Observation for suspected tuberculosis	0.003	0.996	0.000
Z03.3 Observation for suspected nervous system disorder	0.003	0.997	0.000
M48.06 Spinal stenosis (Lumbar region)	0.000	0.997	0.003
M54.2 Cervicalgia	0.003	0.997	0.000
K70 Alcoholic liver disease	0.003	0.997	0.000
Z39.0 Care and examination immediately after delivery	0.003	0.997	0.000
K74.5 Biliary cirrhosis, unspecified	0.003	0.997	0.000
K74.4 Secondary biliary cirrhosis	0.003	0.997	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.003	0.997	0.000
K74.1 Hepatic sclerosis	0.003	0.997	0.000
K74.0 Hepatic fibrosis	0.003	0.997	0.000
M54.5 Low back pain	0.003	0.997	0.000
K75 Other inflammatory liver diseases	0.003	0.997	0.000
K77 Liver disorders in diseases classified elsewhere	0.003	0.997	0.000
K73 Chronic hepatitis, not elsewhere classified	0.003	0.997	0.000
K71 Toxic liver disease	0.003	0.997	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.003	0.997	0.000
Z03.1 Observation for suspected malignant neoplasm	0.003	0.997	0.000
M54 Dorsalgia	0.003	0.997	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.003	0.997	0.000
K70.3 Alcoholic cirrhosis of liver	0.003	0.997	0.000
N95.0 Postmenopausal bleeding	0.000	0.997	0.003
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.003	0.997	0.000
K72 Hepatic failure, not elsewhere classified	0.003	0.997	0.000
M19.91 Arthrosis, unspecified (Shoulder region)	0.000	0.997	0.003
M23.2 Derangement of meniscus due to old tear or injury	0.003	0.997	0.000
K70.1 Alcoholic hepatitis	0.003	0.997	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.003	0.997	0.000
M54.29 Cervicalgia-Site unspe	0.002	0.997	0.000
M54.28 Cervicalgia-Sacral/sacrococ	0.002	0.997	0.000
M54.27 Cervicalgia-Lumbosacral	0.002	0.997	0.000
M54.26 Cervicalgia-Lumbar	0.002	0.997	0.000
M54.25 Cervicalgia-Thoracolumbar	0.002	0.997	0.000
M54.24 Cervicalgia-Thoracic	0.002	0.997	0.000
M54.23 Cervicalgia (Cervicothoracic region)	0.002	0.997	0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.002	0.997	0.000
M54.20 Cervicalgia-Mult site	0.002	0.997	0.000
M54.4 Lumbago with sciatica	0.003	0.997	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.003	0.997	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.000	0.997	0.003
K70.4 Alcoholic hepatic failure	0.002	0.997	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.002	0.997	0.000
K70.0 Alcoholic fatty liver	0.002	0.997	0.000
Z39 Postpartum care and examination	0.003	0.997	0.000
M54.55 Low back pain (Thoracolumbar region)	0.002	0.997	0.000
M54.54 Low back pain-Thoracic	0.002	0.997	0.000
M54.53 Low back pain-Cervicothoracic	0.002	0.997	0.000
M54.52 Low back pain-Cervical	0.002	0.997	0.000
M54.51 Low back pain-Occipit-atl-axl	0.002	0.997	0.000
M54.50 Low back pain (Multiple sites in spine)	0.002	0.997	0.000
K75.4 Autoimmune hepatitis	0.002	0.997	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.002	0.997	0.000
K75.9 Inflammatory liver disease, unspecified	0.002	0.998	0.000
K75.8 Other specified inflammatory liver diseases	0.002	0.998	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.002	0.998	0.000
K75.2 Nonspecific reactive hepatitis	0.002	0.998	0.000
K75.1 Phlebitis of portal vein	0.002	0.998	0.000
K75.0 Abscess of liver	0.002	0.998	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.002	0.998	0.000
K71.9 Toxic liver disease, unspecified	0.002	0.998	0.000
K71.8 Toxic liver disease with other disorders of liver	0.002	0.998	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.002	0.998	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.002	0.998	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.002	0.998	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.002	0.998	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.002	0.998	0.000
K71.2 Toxic liver disease with acute hepatitis	0.002	0.998	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.002	0.998	0.000
K71.0 Toxic liver disease with cholestasis	0.002	0.998	0.000
K73.9 Chronic hepatitis, unspecified	0.002	0.998	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.002	0.998	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.002	0.998	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.002	0.998	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.002	0.998	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.002	0.998	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
M54.1 Radiculopathy	0.002	0.998	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.002	0.998	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.002	0.998	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.002	0.998	0.000
M54.57 Low back pain (Lumbosacral region)	0.002	0.998	0.000
M54.8 Other dorsalgia	0.002	0.998	0.000
M54.6 Pain in thoracic spine	0.002	0.998	0.000
M54.3 Sciatica	0.002	0.998	0.000
M54.0 Panniculitis affecting regions of neck and back	0.002	0.998	0.000
M54.49 Lumbago with sciatica (Site unspecified)	0.002	0.998	0.000
I67 Other cerebrovascular diseases	0.002	0.998	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.002	0.998	0.000
M54.56 Low back pain (Lumbar region)	0.002	0.998	0.000
K72.1 Chronic hepatic failure	0.002	0.998	0.000
K72.0 Acute and subacute hepatic failure	0.002	0.998	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.002	0.998	0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.002	0.998	0.000
K70.9 Alcoholic liver disease, unspecified	0.002	0.998	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.002	0.998	0.000
M48.0 Spinal stenosis	0.000	0.998	0.002
Z31 Procreative management	0.002	0.998	0.000
M50.1 Cervical disk disorder with radiculopathy	0.002	0.998	0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.002	0.998	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.002	0.998	0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.002	0.998	0.000
M54.44 Lumbago with sciatica-Thoracic	0.002	0.998	0.000
M54.43 Lumbago with sciatica-Cervicothoracic	0.002	0.998	0.000
M54.42 Lumbago with sciatica-Cervical	0.002	0.998	0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.002	0.998	0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.002	0.998	0.000
K72.9 Hepatic failure, unspecified	0.002	0.998	0.000
M54.39 Sciatica (Site unspecified)	0.002	0.998	0.000
M23 Internal derangement of knee	0.002	0.998	0.000
S68 Traumatic amputation of wrist and hand	0.002	0.998	0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.002	0.998	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
J98.4 Other disorders of lung	0.002	0.998	0.000
Z39.2 Routine postpartum follow-up	0.002	0.998	0.000
Z39.1 Care and examination of lactating mother	0.002	0.998	0.000
Z36 Antenatal screening	0.002	0.998	0.000
M54.12 Radiculopathy (Cervical region)	0.002	0.998	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.002	0.998	0.000
S64.4 Injury of digital nerve of other finger	0.002	0.998	0.000
M23.8 Other internal derangements of knee	0.002	0.998	0.000
M50 Cervical disk disorders	0.002	0.998	0.000
M54.19 Radiculopathy (Site unspecified)	0.002	0.998	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.002	0.998	0.000
M54.15 Radiculopathy (Thoracolumbar region)	0.002	0.998	0.000
M54.14 Radiculopathy (Thoracic region)	0.002	0.998	0.000
M54.13 Radiculopathy (Cervicothoracic region)	0.002	0.998	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.002	0.998	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.002	0.998	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.002	0.998	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.002	0.998	0.000
M13.94 Arthritis, unspecified (Hand)	0.000	0.998	0.002
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)	0.002	0.998	0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)	0.002	0.998	0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)	0.002	0.998	0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)	0.002	0.998	0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)	0.002	0.998	0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)	0.002	0.998	0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)	0.002	0.998	0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)	0.002	0.998	0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)	0.002	0.998	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M54.37 Sciatica (Lumbosacral region)	0.002	0.998	0.000
M54.35 Sciatica (Thoracolumbar region)	0.002	0.998	0.000
M54.34 Sciatica-Thoracic	0.002	0.998	0.000
M54.33 Sciatica-Cervicothoracic	0.002	0.998	0.000
M54.32 Sciatica-Cervical	0.002	0.998	0.000
M54.31 Sciatica-Occipit-atl-axl	0.002	0.998	0.000
M54.30 Sciatica (Multiple sites in spine)	0.002	0.998	0.000
M54.69 Pain in thoracic spine-Site unspe	0.002	0.998	0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.002	0.998	0.000
M54.67 Pain in thoracic spine-Lumbosacral	0.002	0.998	0.000
M54.66 Pain in thoracic spine-Lumbar	0.002	0.998	0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.002	0.998	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.002	0.998	0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.002	0.998	0.000
M54.62 Pain in thoracic spine-Cervical	0.002	0.998	0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.002	0.998	0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.002	0.998	0.000
M54.89 Other dorsalgia (Site unspecified)	0.002	0.998	0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M54.87 Other dorsalgia (Lumbosacral region)	0.002	0.998	0.000
M54.86 Other dorsalgia (Lumbar region)	0.002	0.998	0.000
M54.85 Other dorsalgia (Thoracolumbar region)	0.002	0.998	0.000
M54.84 Other dorsalgia (Thoracic region)	0.002	0.998	0.000
M54.83 Other dorsalgia (Cervicothoracic region)	0.002	0.998	0.000
M54.82 Other dorsalgia (Cervical region)	0.002	0.998	0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)	0.002	0.998	0.000
M54.80 Other dorsalgia (Multiple sites in spine)	0.002	0.998	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.002	0.998	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.002	0.998	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.002	0.998	0.000
M54.16 Radiculopathy (Lumbar region)	0.002	0.998	0.000
E83.5 Disorders of calcium metabolism	0.002	0.998	0.000
Z03.4 Observation for suspected myocardial infarction	0.002	0.998	0.000
E78.5 Hyperlipidaemia, unspecified	0.002	0.998	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.002	0.998	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.002	0.998	0.000
I67.5 Moyamoya disease	0.002	0.998	0.000
I67.4 Hypertensive encephalopathy	0.002	0.998	0.000
I67.3 Progressive vascular leukoencephalopathy	0.002	0.998	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.002	0.998	0.000
M50-M54 Other dorsopathies	0.002	0.998	0.000
S82.60 Fracture of lateral malleolus (closed)	0.002	0.998	0.000
Z36.9 Antenatal screening, unspecified	0.002	0.998	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.000	0.998	0.002
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
I67.2 Cerebral atherosclerosis	0.002	0.998	0.000
M23.5 Chronic instability of knee	0.002	0.998	0.000
M23.3 Other meniscus derangements	0.002	0.998	0.000
M54.9 Dorsalgia, unspecified	0.002	0.998	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.002	0.998	0.000
S64 Injury of nerves at wrist and hand level	0.002	0.998	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.002	0.998	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M48.05 Spinal stenosis (Thoracolumbar region)	0.000	0.998	0.002
M48.04 Spinal stenosis (Thoracic region)	0.000	0.998	0.002
M48.03 Spinal stenosis (Cervicothoracic region)	0.000	0.998	0.002
M48.02 Spinal stenosis (Cervical region)	0.000	0.998	0.002
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.000	0.998	0.002
M48.00 Spinal stenosis (Multiple sites in spine)	0.000	0.998	0.002
Z22.3 Carrier of other specified bacterial diseases	0.002	0.998	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.002	0.998	0.000
Z35 Supervision of high-risk pregnancy	0.002	0.998	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.002	0.998	0.000
Z31.9 Procreative management, unspecified	0.002	0.998	0.000
Z31.8 Other procreative management	0.002	0.998	0.000
Z31.6 General counselling and advice on procreation	0.002	0.998	0.000
Z31.5 Genetic counselling	0.002	0.998	0.000
Z31.4 Procreative investigation and testing	0.002	0.998	0.000
Z31.3 Other assisted fertilisation methods	0.002	0.998	0.000
Z31.2 In vitro fertilisation	0.002	0.998	0.000
Z31.1 Artifical insemination	0.002	0.998	0.000
M50.0 Cervical disk disorder with myelopathy	0.002	0.998	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
M13.9 Arthritis, unspecified	0.000	0.998	0.002
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.002	0.998	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.002	0.998	0.000
S68.4 Traumatic amputation of hand at wrist level	0.002	0.998	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.002	0.998	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.002	0.998	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.002	0.998	0.000
M54.36 Sciatica (Lumbar region)	0.002	0.998	0.000
M23.9 Internal derangement of knee, unspecified	0.002	0.998	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.002	0.998	0.000
M23.1 Discoid meniscus (congenital)	0.002	0.998	0.000
M23.0 Cystic meniscus	0.002	0.998	0.000
Z36.5 Antenatal screening for isoimmunisation	0.002	0.998	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.002	0.998	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.002	0.998	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.002	0.998	0.000
Z72.0 Tobacco use	0.002	0.998	0.000
Z22 Carrier of infectious disease	0.002	0.998	0.000
Z38 Liveborn infants according to place of birth	0.002	0.998	0.000
Z32 Pregnancy examination and test	0.002	0.998	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.002	0.998	0.000
Z33 Pregnant state, incidental	0.002	0.998	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.000	0.998	0.002
M23.87 Other internal derangements of knee (Capsular ligament)	0.002	0.998	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.002	0.998	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.002	0.998	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.002	0.998	0.000
I67.1 Cerebral aneurysm, nonruptured	0.002	0.998	0.000
M50.9 Cervical disk disorder, unspecified	0.002	0.998	0.000
M50.8 Other cervical disk disorders	0.002	0.998	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
S82.6 Fracture of lateral malleolus	0.002	0.998	0.000
Chapter XXI Factors influencing health status and contact with health services	0.002	0.998	0.000
M23.4 Loose body in knee	0.002	0.998	0.000
M50.3 Other cervical disk degeneration	0.002	0.998	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.002	0.998	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.002	0.998	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.002	0.998	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.002	0.998	0.000
T83.2 Mechanical complication of graft of urinary organ	0.002	0.998	0.000
Z36.8 Other antenatal screening	0.002	0.998	0.000
S60-S69 Injuries to the wrist and hand	0.002	0.998	0.000
M48.09 Spinal stenosis (Site unspecified)	0.000	0.998	0.001
M50.2 Other cervical disk displacement	0.002	0.998	0.000
R32 Unspecified urinary incontinence	0.002	0.998	0.000
Z35.5 Supervision of elderly primigravida	0.002	0.998	0.000
M53 Other dorsopathies, not elsewhere classified	0.002	0.998	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.002	0.998	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.001	0.998	0.000
M23.37 Other meniscus derangements-Capsular lig	0.001	0.998	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.001	0.998	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.001	0.998	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.998	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.001	0.998	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.001	0.998	0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.001	0.998	0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.001	0.998	0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.001	0.998	0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.001	0.998	0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.001	0.998	0.000
M23.50 Chronic instability of knee (Multiple sites)	0.001	0.998	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.001	0.998	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.001	0.998	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.001	0.998	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.001	0.998	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.001	0.998	0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.001	0.998	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.001	0.998	0.000
S60 Superficial injury of wrist and hand	0.002	0.998	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.001	0.998	0.000
S64.8 Injury of other nerves at wrist and hand level	0.001	0.998	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.001	0.998	0.000
S64.3 Injury of digital nerve of thumb	0.001	0.998	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.001	0.998	0.000
S64.1 Injury of median nerve at wrist and hand level	0.001	0.998	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.001	0.998	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.001	0.998	0.000
Z35.8 Supervision of other high-risk pregnancies	0.001	0.998	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.001	0.998	0.000
Z35.6 Supervision of very young primigravida	0.001	0.998	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.001	0.998	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.001	0.998	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.001	0.998	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.001	0.998	0.000
Z29 Need for other prophylactic measures	0.002	0.998	0.000
M13.98 Arthritis, unspecified (Other)	0.000	0.998	0.001
M54.96 Dorsalgia, unspecified (Lumbar region)	0.001	0.998	0.000
I67.8 Other specified cerebrovascular diseases	0.001	0.998	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.001	0.998	0.000
J98 Other respiratory disorders	0.002	0.998	0.000
R10.3 Pain localised to other parts of lower abdomen	0.000	0.998	0.002
S60.9 Superficial injury of wrist and hand, unspecified	0.001	0.998	0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device	0.002	0.998	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.002	0.998	0.000
T86 Failure and rejection of transplanted organs and tissues	0.001	0.998	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.001
M13.93 Arthritis, unspecified (Forearm)	0.000	0.998	0.001
M13.92 Arthritis, unspecified (Upper arm)	0.000	0.998	0.001
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.001	0.998	0.000
M23.07 Cystic meniscus-Capsular lig	0.001	0.998	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.001	0.998	0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.001	0.998	0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.001	0.998	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.001	0.998	0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.001	0.998	0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.998	0.000
M23.00 Cystic meniscus (Multiple sites)	0.001	0.998	0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.001	0.998	0.000
M23.17 Discoid meniscus (congenital)-Capsular lig	0.001	0.998	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.001	0.998	0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.001	0.998	0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.001	0.998	0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.001	0.998	0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.001	0.998	0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.998	0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.001	0.998	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.001	0.998	0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.001	0.998	0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.001	0.998	0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.001	0.998	0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.001	0.998	0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.001	0.998	0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.001	0.998	0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.001	0.998	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.998	0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.001	0.998	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.001	0.998	0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.001	0.998	0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.001	0.998	0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.001	0.998	0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.001	0.998	0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.001	0.998	0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.001	0.998	0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.998	0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.001	0.998	0.000
J98.1 Pulmonary collapse	0.002	0.998	0.000
Z22.9 Carrier of infectious disease, unspecified	0.001	0.998	0.000
Z22.8 Carrier of other infectious diseases	0.001	0.998	0.000
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection	0.001	0.998	0.000
Z22.5 Carrier of viral hepatitis	0.001	0.998	0.000
Z22.4 Carrier of infections with a predominantly sexual mode of transmission	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations