TreeWAS – Variant ID: rs1473500

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.988	0.012
# Top node	0.987	0.013
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.983	0.017
Chapter XX External causes of morbidity and mortality	0.980	0.020
Chapter XV Pregnancy, childbirth and the puerperium	0.965	0.035
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.955	0.045
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.950	0.050
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.926	0.074
Chapter XII Diseases of the skin and subcutaneous tissue	0.921	0.079
Y43 Primarily systemic agents	0.918	0.082
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.915	0.085
Chapter IX Diseases of the circulatory system	0.909	0.091
T81 Complications of procedures, not elsewhere classified	0.908	0.092
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.905	0.095
I60-I69 Cerebrovascular diseases	0.904	0.096
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.903	0.097
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.891	0.109
D70-D77 Other diseases of blood and blood-forming organs	0.885	0.115
Chapter I Certain infectious and parasitic diseases	0.881	0.119
Y43.3 Other antineoplastic drugs	0.880	0.120
Q60-Q64 Congenital malformations of the urinary system	0.877	0.123
I63 Cerebral infarction	0.876	0.124
S40-S49 Injuries to the shoulder and upper arm	0.871	0.129
O20-O29 Other maternal disorders predominantly related to pregnancy	0.864	0.136
T85 Complications of other internal prosthetic devices, implants and grafts	0.864	0.136
S60-S69 Injuries to the wrist and hand	0.857	0.143
D70 Agranulocytosis	0.857	0.143
O32 Maternal care for known or suspected malpresentation of foetus	0.847	0.153
I63.9 Cerebral infarction, unspecified	0.844	0.156
I70-I79 Diseases of arteries, arterioles and capillaries	0.844	0.156
W00-W19 Falls	0.843	0.157
L00-L08 Infections of the skin and subcutaneous tissue	0.839	0.161
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.834	0.166
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.832	0.168
Q61 Cystic kidney disease	0.824	0.176
I69 Sequelae of cerebrovascular disease	0.822	0.178
S80-S89 Injuries to the knee and lower leg	0.819	0.181
Y40 Systemic antibiotics	0.816	0.184
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.814	0.186
T81.4 Infection following a procedure, not elsewhere classified	0.810	0.190
T86 Failure and rejection of transplanted organs and tissues	0.808	0.192
Chapter VI Diseases of the nervous system	0.808	0.192
O16 Unspecified maternal hypertension	0.806	0.194
L20-L30 Dermatitis and eczema	0.801	0.199
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.793	0.207
L02 Cutaneous abscess, furuncle and carbuncle	0.788	0.212
A30-A49 Other bacterial diseases	0.787	0.213
I64 Stroke, not specified as haemorrhage or infarction	0.787	0.213
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.786	0.214
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.784	0.216
T91 Sequelae of injuries of neck and trunk	0.781	0.219
T92 Sequelae of injuries of upper limb	0.775	0.225
I61 Intracerebral haemorrhage	0.771	0.229
V80-V89 Other land transport accidents	0.770	0.230
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.765	0.235
X58-X59 Accidental exposure to other and unspecified factors	0.757	0.243
T80 Complications following infusion, transfusion and therapeutic injection	0.757	0.243
Y41 Other systemic anti-infectives and antiparasitics	0.757	0.243
Q00-Q07 Congenital malformations of the nervous system	0.751	0.248
Y52 Agents primarily affecting the cardiovascular system	0.751	0.249
Chapter XXII Codes for special purposes	0.749	0.251
T81.3 Disruption of operation wound, not elsewhere classified	0.747	0.253
Q61.2 Polycystic kidney, adult type	0.745	0.255
S49 Other and unspecified injuries of shoulder and upper arm	0.744	0.256
Y60-Y69 Misadventures to patients during surgical and medical care	0.742	0.258
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.742	0.258
Q50-Q56 Congenital malformations of genital organs	0.739	0.261
L80-L99 Other disorders of the skin and subcutaneous tissue	0.739	0.261
T81.7 Vascular complications following a procedure, not elsewhere classified	0.737	0.263
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.736	0.264
B15-B19 Viral hepatitis	0.736	0.264
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.735	0.265
O32.1 Maternal care for breech presentation	0.734	0.266
O30 Multiple gestation	0.733	0.267
S20-S29 Injuries to the thorax	0.732	0.268
X20-X29 Contact with venomous animals and plants	0.730	0.270
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.729	0.271
W07 Fall involving chair	0.729	0.271
T84.0 Mechanical complication of internal joint prosthesis	0.729	0.271
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.728	0.272
I71 Aortic aneurysm and dissection	0.728	0.272
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.724	0.276
Q20-Q28 Congenital malformations of the circulatory system	0.723	0.277
S69 Other and unspecified injuries of wrist and hand	0.723	0.277
T36-T50 Poisoning by drugs, medicaments and biological substances	0.722	0.278
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.722	0.278
Y43.1 Antineoplastic antimetabolites	0.722	0.278
D80-D89 Certain disorders involving the immune mechanism	0.720	0.280
S62 Fracture at wrist and hand level	0.719	0.281
T83.0 Mechanical complication of urinary (indwelling) catheter	0.718	0.282
O26 Maternal care for other conditions predominantly related to pregnancy	0.716	0.284
I69.1 Sequelae of intracerebral haemorrhage	0.716	0.284
Q80-Q89 Other congenital malformations	0.715	0.285
O20 Haemorrhage in early pregnancy	0.714	0.286
L50-L54 Urticaria and erythema	0.713	0.287
S90-S99 Injuries to the ankle and foot	0.711	0.289
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.711	0.289
O47 False labour	0.709	0.291
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.709	0.291
T79-T79 Certain early complications of trauma	0.708	0.291
T33-T35 Frostbite	0.708	0.291
T26-T28 Burns and corrosions confined to eye and internal organs	0.708	0.291
T20-T25 Burns and corrosions of external body surface, specified by site	0.708	0.291
T00-T07 Injuries involving multiple body regions	0.708	0.291
S10-S19 Injuries to the neck	0.708	0.291
D60-D64 Aplastic and other anaemias	0.708	0.292
Chapter XVI Certain conditions originating in the perinatal period	0.708	0.292
O44 Placenta praevia	0.706	0.294
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.705	0.295
T87 Complications peculiar to reattachment and amputation	0.704	0.295
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.703	0.296
Y35-Y36 Legal intervention and operations of war	0.703	0.297
Y10-Y34 Event of undetermined intent	0.703	0.297
Y00-Y09 Assault	0.703	0.297
X85-X99 Assault	0.703	0.297
X50-X57 Overexertion, travel and privation	0.703	0.297
X40-X49 Accidental poisoning by and exposure to noxious substances	0.703	0.297
X30-X39 Exposure to forces of nature	0.703	0.297
X10-X19 Contact with heat and hot substances	0.703	0.297
X00-X09 Exposure to smoke, fire and flames	0.703	0.297
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.703	0.297
W75-W84 Other accidental threats to breathing	0.703	0.297
W65-W74 Accidental drowning and submersion	0.703	0.297
W50-W64 Exposure to animate mechanical forces	0.703	0.297
V98-V99 Other and unspecified transport accidents	0.703	0.297
V95-V97 Air and space transport accidents	0.703	0.297
V90-V94 Water transport accidents	0.703	0.297
V70-V79 Bus occupant injured in transport accident	0.703	0.297
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.703	0.297
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.703	0.297
V40-V49 Car occupant injured in transport accident	0.703	0.297
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.703	0.297
V01-V09 Pedestrian injured in transport accident	0.703	0.297
S81 Open wound of lower leg	0.702	0.298
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.700	0.300
L91 Hypertrophic disorders of skin	0.700	0.300
W20-W49 Exposure to inanimate mechanical forces	0.698	0.302
Y40.8 Other systemic antibiotics	0.696	0.304
I60 Subarachnoid haemorrhage	0.696	0.304
L27 Dermatitis due to substances taken internally	0.696	0.304
Q61.3 Polycystic kidney, unspecified	0.695	0.305
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.694	0.306
O46 Antepartum haemorrhage, not elsewhere classified	0.694	0.306
T88 Other complications of surgical and medical care, not elsewhere classified	0.693	0.307
O85-O92 Complications predominantly related to the puerperium	0.692	0.308
T31 Burns classified according to extent of body surface involved	0.689	0.311
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.689	0.311
S40 Superficial injury of shoulder and upper arm	0.689	0.311
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.688	0.312
O41 Other disorders of amniotic fluid and membranes	0.688	0.312
S70-S79 Injuries to the hip and thigh	0.687	0.313
T84.3 Mechanical complication of other bone devices, implants and grafts	0.686	0.314
A41 Other septicaemia	0.686	0.314
O34 Maternal care for known or suspected abnormality of pelvic organs	0.686	0.314
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.686	0.314
Y59 Other and unspecified vaccines and biological substances	0.685	0.315
Y58 Bacterial vaccines	0.685	0.315
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.685	0.315
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.685	0.315
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.685	0.315
Y53 Agents primarily affecting the gastro-intestinal system	0.685	0.315
Y50 Central nervous system stimulants, not elsewhere classified	0.685	0.315
Y49 Psychotropic drugs, not elsewhere classified	0.685	0.315
Y48 Anaesthetics and therapeutic gases	0.685	0.315
Y47 Sedatives, hypnotics and antianxiety drugs	0.685	0.315
Y46 Antiepileptics and anti-Parkinsonism drugs	0.685	0.315
T15-T19 Effects of foreign body entering through natural orifice	0.684	0.316
V20-V29 Motorcycle rider injured in transport accident	0.684	0.316
B95-B98 Bacterial, viral and other infectious agents	0.684	0.316
Chapter VIII Diseases of the ear and mastoid process	0.681	0.319
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.681	0.319
Q35-Q37 Cleft lip and cleft palate	0.681	0.319
Q30-Q34 Congenital malformations of the respiratory system	0.681	0.319
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.681	0.319
Y43.4 Immunosuppressive agents	0.678	0.321
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.678	0.322
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.678	0.322
S60 Superficial injury of wrist and hand	0.677	0.323
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.675	0.325
O35 Maternal care for known or suspected foetal abnormality and damage	0.674	0.326
S66 Injury of muscle and tendon at wrist and hand level	0.674	0.326
T65 Toxic effect of other and unspecified substances	0.673	0.327
Q38-Q45 Other congenital malformations of the digestive system	0.672	0.328
Y57 Other and unspecified drugs and medicaments	0.672	0.328
O43 Placental disorders	0.671	0.329
O23 Infections of genito-urinary tract in pregnancy	0.671	0.329
O32.2 Maternal care for transverse and oblique lie	0.669	0.331
A50-A64 Infections with a predominantly sexual mode of transmission	0.669	0.331
O80-O84 Delivery	0.669	0.331
O14.9 Preeclampsia, unspecified	0.669	0.331
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.668	0.332
Y84.8 Other medical procedures	0.668	0.332
I70 Atherosclerosis	0.667	0.333
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.667	0.333
I74 Arterial embolism and thrombosis	0.667	0.333
X60-X84 Intentional self-harm	0.667	0.333
S46 Injury of muscle and tendon at shoulder and upper arm level	0.666	0.334
D55-D59 Haemolytic anaemias	0.664	0.336
T85.2 Mechanical complication of intraocular lens	0.664	0.336
D73 Diseases of spleen	0.661	0.339
L10-L14 Bullous disorders	0.660	0.340
M70-M79 Other soft tissue disorders	0.660	0.340
Y43.9 Primarily systemic agent, unspecified	0.658	0.342
Y43.8 Other primarily systemic agents, not elsewhere classified	0.658	0.342
Y43.6 Enzymes, not elsewhere classified	0.658	0.342
Y43.5 Acidifying and alkalising agents	0.658	0.342
Y43.2 Antineoplastic natural products	0.658	0.342
Y43.0 Antiallergic and antiemetic drugs	0.658	0.342
L08 Other local infections of skin and subcutaneous tissue	0.658	0.342
L91.8 Other hypertrophic disorders of skin	0.658	0.342
T93 Sequelae of injuries of lower limb	0.657	0.343
D75 Other diseases of blood and blood-forming organs	0.656	0.344
O45 Premature separation of placenta [abruptio placentae]	0.656	0.344
O33 Maternal care for known or suspected disproportion	0.656	0.344
O31 Complications specific to multiple gestation	0.656	0.344
O40 Polyhydramnios	0.656	0.344
S49.9 Unspecified injury of shoulder and upper arm	0.653	0.347
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.652	0.348
O00-O08 Pregnancy with abortive outcome	0.652	0.348
I00-I02 Acute rheumatic fever	0.652	0.348
T81.9 Unspecified complication of procedure	0.651	0.349
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.651	0.349
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.651	0.349
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.650	0.349
W06 Fall involving bed	0.650	0.350
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.650	0.350
O15 Eclampsia	0.649	0.351
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.649	0.351
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.649	0.351
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.649	0.351
I68 Cerebrovascular disorders in diseases classified elsewhere	0.648	0.352
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.648	0.352
G90-G99 Other disorders of the nervous system	0.648	0.352
W07.0 Home	0.647	0.353
T98 Sequelae of other and unspecified effects of external causes	0.647	0.353
T95 Sequelae of burns, corrosions and frostbite	0.647	0.353
T94 Sequelae of injuries involving multiple and unspecified body regions	0.647	0.353
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.647	0.353
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.647	0.353
B35-B49 Mycoses	0.647	0.353
V10-V19 Pedal cyclist injured in transport accident	0.646	0.354
S00-S09 Injuries to the head	0.646	0.354
L29 Pruritus	0.645	0.355
T86.8 Failure and rejection of other transplanted organs and tissues	0.644	0.356
B90-B94 Sequelae of infectious and parasitic diseases	0.642	0.357
L05 Pilonidal cyst	0.642	0.357
I73 Other peripheral vascular diseases	0.642	0.358
I77 Other disorders of arteries and arterioles	0.642	0.358
T91.3 Sequelae of injury of spinal cord	0.641	0.359
M72 Fibroblastic disorders	0.639	0.361
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.639	0.361
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.639	0.361
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.639	0.361
G80-G83 Cerebral palsy and other paralytic syndromes	0.637	0.363
Y40.0 Penicillins	0.637	0.363
Q63 Other congenital malformations of kidney	0.636	0.364
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.636	0.364
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.636	0.364
T90 Sequelae of injuries of head	0.635	0.365
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.635	0.365
D74 Methaemoglobinaemia	0.635	0.365
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.635	0.365
D71 Functional disorders of polymorphonuclear neutrophils	0.635	0.365
S64 Injury of nerves at wrist and hand level	0.635	0.365
H60-H62 Diseases of external ear	0.634	0.366
T86.1 Kidney transplant failure and rejection	0.633	0.367
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.632	0.368
B99-B99 Other infectious diseases	0.632	0.368
B85-B89 Pediculosis, acariasis and other infestations	0.632	0.368
B65-B83 Helminthiases	0.632	0.368
B50-B64 Protozoal diseases	0.632	0.368
B20-B24 Human immunodeficiency virus [HIV] disease	0.632	0.368
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.632	0.368
A80-A89 Viral infections of the central nervous system	0.632	0.368
A75-A79 Rickettsioses	0.632	0.368
A70-A74 Other diseases caused by chlamydiae	0.632	0.368
A65-A69 Other spirochaetal diseases	0.632	0.368
A20-A28 Certain zoonotic bacterial diseases	0.632	0.368
A15-A19 Tuberculosis	0.632	0.368
Y44 Agents primarily affecting blood constituents	0.631	0.369
S86 Injury of muscle and tendon at lower leg level	0.630	0.370
L28 Lichen simplex chronicus and prurigo	0.630	0.370
I61.9 Intracerebral haemorrhage, unspecified	0.630	0.370
Q64 Other congenital malformations of urinary system	0.629	0.371
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.629	0.371
Q60 Renal agenesis and other reduction defects of kidney	0.629	0.371
I63.8 Other cerebral infarction	0.628	0.372
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.628	0.372
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.628	0.372
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.628	0.372
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.628	0.372
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.628	0.372
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.625	0.375
S48 Traumatic amputation of shoulder and upper arm	0.625	0.375
S45 Injury of blood vessels at shoulder and upper arm level	0.625	0.375
S44 Injury of nerves at shoulder and upper arm level	0.625	0.375
S41 Open wound of shoulder and upper arm	0.625	0.375
S47 Crushing injury of shoulder and upper arm	0.625	0.375
O14.0 Moderate preeclampsia	0.624	0.376
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.624	0.376
O26.8 Other specified pregnancy-related conditions	0.623	0.377
T84.2 Mechanical complication of internal fixation device of other bones	0.623	0.377
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.623	0.377
I61.5 Intracerebral haemorrhage, intraventricular	0.623	0.377
T83.3 Mechanical complication of intra-uterine contraceptive device	0.622	0.378
S62.6 Fracture of other finger	0.621	0.379
T81.8 Other complications of procedures, not elsewhere classified	0.621	0.379
L27.0 Generalised skin eruption due to drugs and medicaments	0.620	0.380
T91.1 Sequelae of fracture of spine	0.620	0.380
O29 Complications of anaesthesia during pregnancy	0.620	0.380
O28 Abnormal findings on antenatal screening of mother	0.620	0.380
O24 Diabetes mellitus in pregnancy	0.620	0.380
O22 Venous complications in pregnancy	0.620	0.380
O21 Excessive vomiting in pregnancy	0.620	0.380
O25 Malnutrition in pregnancy	0.620	0.380
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.620	0.380
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.620	0.380
A46 Erysipelas	0.619	0.381
G35-G37 Demyelinating diseases of the central nervous system	0.619	0.381
Q61.0 Congenital single renal cyst	0.619	0.381
T92.2 Sequelae of fracture at wrist and hand level	0.619	0.381
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified	0.619	0.381
O36 Maternal care for other known or suspected foetal problems	0.618	0.382
B97 Viral agents as the cause of diseases classified to other chapters	0.618	0.382
I62 Other nontraumatic intracranial haemorrhage	0.616	0.384
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.615	0.384
A40 Streptococcal septicaemia	0.615	0.384
S65 Injury of blood vessels at wrist and hand level	0.615	0.385
I69.3 Sequelae of cerebral infarction	0.615	0.385
Y51 Drugs primarily affecting the autonomic nervous system	0.614	0.385
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.614	0.386
G00-G09 Inflammatory diseases of the central nervous system	0.613	0.387
G50-G59 Nerve, nerve root and plexus disorders	0.612	0.388
S80 Superficial injury of lower leg	0.611	0.389
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.610	0.390
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.610	0.390
Q05 Spina bifida	0.609	0.391
B16 Acute hepatitis B	0.608	0.392
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.608	0.392
O32.9 Maternal care for malpresentation of foetus, unspecified	0.607	0.392
O32.8 Maternal care for other malpresentation of foetus	0.607	0.392
O32.6 Maternal care for compound presentation	0.607	0.392
O32.4 Maternal care for high head at term	0.607	0.392
O32.3 Maternal care for face, brow and chin presentation	0.607	0.392
O32.0 Maternal care for unstable lie	0.607	0.392
I69.0 Sequelae of subarachnoid haemorrhage	0.607	0.393
I72 Other aneurysm	0.607	0.393
S69.7 Multiple injuries of wrist and hand	0.607	0.393
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.607	0.393
Y52.4 Angiotensin-converting-enzyme inhibitors	0.605	0.394
L89 Decubitus ulcer	0.605	0.395
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.605	0.395
O94-O99 Other obstetric conditions, not elsewhere classified	0.605	0.395
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.605	0.395
W18 Other fall on same level	0.604	0.396
W17 Other fall from one level to another	0.604	0.396
W16 Diving or jumping into water causing injury other than drowning or submersion	0.604	0.396
W15 Fall from cliff	0.604	0.396
W14 Fall from tree	0.604	0.396
W12 Fall on and from scaffolding	0.604	0.396
W11 Fall on and from ladder	0.604	0.396
W10 Fall on and from stairs and steps	0.604	0.396
W09 Fall involving playground equipment	0.604	0.396
W08 Fall involving other furniture	0.604	0.396
W05 Fall involving wheelchair	0.604	0.396
W04 Fall while being carried or supported by other persons	0.604	0.396
W03 Other fall on same level due to collision with, or pushing by, another person	0.604	0.396
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.604	0.396
W01 Fall on same level from slipping, tripping and stumbling	0.604	0.396
W00 Fall on same level involving ice and snow	0.604	0.396
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.603	0.397
O30.0 Twin pregnancy	0.602	0.398
L04 Acute lymphadenitis	0.602	0.398
L01 Impetigo	0.602	0.398
L00 Staphylococcal scalded skin syndrome	0.602	0.398
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.601	0.398
W19 Unspecified fall	0.601	0.399
T31.0 Burns involving less than 10% of body surface	0.600	0.400
X59 Exposure to unspecified factor	0.598	0.402
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.597	0.403
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.597	0.403
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.597	0.403
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.597	0.403
T83.2 Mechanical complication of graft of urinary organ	0.597	0.403
T83.1 Mechanical complication of other urinary devices and implants	0.597	0.403
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.596	0.404
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.593	0.406
L84 Corns and callosities	0.594	0.406
T65.9 Toxic effect of unspecified substance	0.593	0.407
I78 Diseases of capillaries	0.593	0.407
S89 Other and unspecified injuries of lower leg	0.593	0.407
W13 Fall from, out of or through building or structure	0.592	0.408
T91.8 Sequelae of other specified injuries of neck and trunk	0.591	0.409
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.591	0.409
Q61.9 Cystic kidney disease, unspecified	0.591	0.409
Q61.8 Other cystic kidney diseases	0.591	0.409
Q61.5 Medullary cystic kidney	0.591	0.409
Q61.4 Renal dysplasia	0.591	0.409
Q61.1 Polycystic kidney, infantile type	0.591	0.409
I95-I99 Other and unspecified disorders of the circulatory system	0.590	0.410
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.590	0.410
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.590	0.410
M40-M43 Deforming dorsopathies	0.588	0.412
S67 Crushing injury of wrist and hand	0.588	0.412
S88 Traumatic amputation of lower leg	0.587	0.413
S87 Crushing injury of lower leg	0.587	0.413
S85 Injury of blood vessels at lower leg level	0.587	0.413
S84 Injury of nerves at lower leg level	0.587	0.413
Y88 Sequelae of surgical and medical care as external cause	0.587	0.413
S50-S59 Injuries to the elbow and forearm	0.586	0.414
Y40.7 Antifungal antibiotics, systemically used	0.585	0.415
Y40.6 Rifamycins	0.585	0.415
Y40.5 Aminoglycosides	0.585	0.415
Y40.4 Tetracyclines	0.585	0.415
Y40.3 Macrolides	0.585	0.415
Y40.2 Chloramphenicol group	0.585	0.415
Y40.1 Cefalosporins and other -lactam antibiotics	0.585	0.415
G93 Other disorders of brain	0.585	0.415
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.584	0.416
T32 Corrosions classified according to extent of body surface involved	0.584	0.416
T30 Burn and corrosion, body region unspecified	0.584	0.416
T29 Burns and corrosions of multiple body regions	0.584	0.416
O48 Prolonged pregnancy	0.583	0.417
S22 Fracture of rib(s), sternum and thoracic spine	0.583	0.417
D50-D53 Nutritional anaemias	0.583	0.417
Y84.1 Kidney dialysis	0.582	0.418
M65-M68 Disorders of synovium and tendon	0.581	0.419
L53 Other erythematous conditions	0.580	0.420
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.580	0.420
L95 Vasculitis limited to skin, not elsewhere classified	0.579	0.421
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.579	0.421
T86.4 Liver transplant failure and rejection	0.579	0.421
T86.3 Heart-lung transplant failure and rejection	0.579	0.421
T86.2 Heart transplant failure and rejection	0.579	0.421
T86.0 Bone-marrow transplant rejection	0.579	0.421
G70-G73 Diseases of myoneural junction and muscle	0.579	0.421
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.579	0.421
O20.0 Threatened abortion	0.579	0.421
L40-L45 Papulosquamous disorders	0.578	0.422
T66-T78 Other and unspecified effects of external causes	0.577	0.422
T63 Toxic effect of contact with venomous animals	0.577	0.423
A41.8 Other specified septicaemia	0.575	0.425
L25 Unspecified contact dermatitis	0.574	0.425
L24 Irritant contact dermatitis	0.574	0.425
L23 Allergic contact dermatitis	0.574	0.425
L21 Seborrhoeic dermatitis	0.574	0.425
L20 Atopic dermatitis	0.574	0.425
L26 Exfoliative dermatitis	0.574	0.425
L22 Diaper [napkin] dermatitis	0.574	0.425
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.571	0.429
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.571	0.429
D62 Acute posthaemorrhagic anaemia	0.571	0.429
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.571	0.429
Y79 Orthopaedic devices associated with adverse incidents	0.571	0.429
Q65 Congenital deformities of hip	0.571	0.429
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.570	0.430
Y40.9 Systemic antibiotic, unspecified	0.569	0.431
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.567	0.432
B18 Chronic viral hepatitis	0.567	0.432
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.567	0.433
L81 Other disorders of pigmentation	0.567	0.433
Q27 Other congenital malformations of peripheral vascular system	0.567	0.433
L91.0 Keloid scar	0.567	0.433
D72 Other disorders of white blood cells	0.566	0.433
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.565	0.435
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.565	0.435
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.565	0.435
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.565	0.435
A48 Other bacterial diseases, not elsewhere classified	0.564	0.435
A44 Bartonellosis	0.564	0.435
A43 Nocardiosis	0.564	0.435
A42 Actinomycosis	0.564	0.435
A39 Meningococcal infection	0.564	0.435
A37 Whooping cough	0.564	0.435
A36 Diphtheria	0.564	0.435
A32 Listeriosis	0.564	0.435
A31 Infection due to other mycobacteria	0.564	0.435
A30 Leprosy [Hansen's disease]	0.564	0.435
A38 Scarlet fever	0.564	0.435
A35 Other tetanus	0.564	0.435
A34 Obstetrical tetanus	0.564	0.435
A33 Tetanus neonatorum	0.564	0.435
S81.9 Open wound of lower leg, part unspecified	0.564	0.436
O14.2 HELLP syndrome	0.564	0.436
O14.1 Severe preeclampsia	0.564	0.436
H60 Otitis externa	0.563	0.437
T62 Toxic effect of other noxious substances eaten as food	0.562	0.438
T61 Toxic effect of noxious substances eaten as seafood	0.562	0.438
T60 Toxic effect of pesticides	0.562	0.438
T59 Toxic effect of other gases, fumes and vapours	0.562	0.438
T57 Toxic effect of other inorganic substances	0.562	0.438
T56 Toxic effect of metals	0.562	0.438
T54 Toxic effect of corrosive substances	0.562	0.438
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.562	0.438
T52 Toxic effect of organic solvents	0.562	0.438
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.562	0.438
T58 Toxic effect of carbon monoxide	0.562	0.438
T55 Toxic effect of soaps and detergents	0.562	0.438
M80-M85 Disorders of bone density and structure	0.562	0.438
O47.0 False labour before 37 completed weeks of gestation	0.560	0.440

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations