TreeWAS – Variant ID: rs1531517

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	0.000	0.000	1.000
M20-M25 Other joint disorders	0.988	0.012	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.988	0.012	0.000
M15-M19 Arthrosis	0.986	0.014	0.000
M19 Other arthrosis	0.979	0.021	0.000
M25 Other joint disorders, not elsewhere classified	0.978	0.022	0.000
M19.9 Arthrosis, unspecified	0.953	0.047	0.000
M19.97 Arthrosis, unspecified (Ankle and foot)	0.948	0.052	0.000
M20 Acquired deformities of fingers and toes	0.948	0.052	0.000
M40-M43 Deforming dorsopathies	0.945	0.055	0.000
M21 Other acquired deformities of limbs	0.941	0.059	0.000
M25.4 Effusion of joint	0.927	0.073	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.920	0.080	0.000
M25.5 Pain in joint	0.914	0.086	0.000
M20.5 Other deformities of toe(s) (acquired)	0.913	0.087	0.000
M19.0 Primary arthrosis of other joints	0.906	0.094	0.000
M70-M79 Other soft tissue disorders	0.904	0.096	0.000
M16 Coxarthrosis [arthrosis of hip]	0.895	0.105	0.000
M34 Systemic sclerosis	0.893	0.107	0.000
M21.2 Flexion deformity	0.893	0.107	0.000
M43 Other deforming dorsopathies	0.890	0.110	0.000
M25.46 Effusion of joint (Lower leg)	0.887	0.113	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.878	0.122	0.000
M25.56 Pain in joint (Lower leg)	0.876	0.124	0.000
M18 Arthrosis of first carpometacarpal joint	0.872	0.128	0.000
M75 Shoulder lesions	0.853	0.147	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.851	0.149	0.000
M43.1 Spondylolisthesis	0.836	0.164	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.825	0.175	0.000
M21.6 Other acquired deformities of ankle and foot	0.821	0.179	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.819	0.181	0.000
M20.3 Other deformity of hallux (acquired)	0.816	0.184	0.000
M16.9 Coxarthrosis, unspecified	0.814	0.186	0.000
M25.51 Pain in joint (Shoulder region)	0.811	0.189	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.811	0.189	0.000
M32 Systemic lupus erythematosus	0.805	0.195	0.000
M25.3 Other instability of joint	0.803	0.197	0.000
M21.24 Flexion deformity (Hand)	0.798	0.202	0.000
M80-M85 Disorders of bone density and structure	0.797	0.203	0.000
M75.5 Bursitis of shoulder	0.797	0.203	0.000
M24 Other specific joint derangements	0.795	0.205	0.000
M41 Scoliosis	0.790	0.210	0.000
M34.8 Other forms of systemic sclerosis	0.784	0.216	0.000
M25.0 Haemarthrosis	0.783	0.217	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.782	0.218	0.000
M19.1 Posttraumatic arthrosis of other joints	0.782	0.218	0.000
M30 Polyarteritis nodosa and related conditions	0.779	0.221	0.000
M91-M94 Chondropathies	0.778	0.222	0.000
M25.59 Pain in joint (Site unspecified)	0.777	0.223	0.000
M75.2 Bicipital tendinitis	0.775	0.225	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.765	0.235	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.760	0.240	0.000
M70.6 Trochanteric bursitis	0.754	0.246	0.000
M21.26 Flexion deformity (Lower leg)	0.748	0.252	0.000
M34.9 Systemic sclerosis, unspecified	0.747	0.253	0.000
M86-M90 Other osteopathies	0.746	0.254	0.000
M25.44 Effusion of joint (Hand)	0.744	0.256	0.000
M21.0 Valgus deformity, not elsewhere classified	0.740	0.260	0.000
M16.1 Other primary coxarthrosis	0.734	0.266	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.734	0.266	0.000
M21.27 Flexion deformity (Ankle and foot)	0.731	0.269	0.000
M25.9 Joint disorder, unspecified	0.730	0.270	0.000
M15 Polyarthrosis	0.726	0.274	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.720	0.279	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.718	0.282	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.709	0.291	0.000
M33 Dermatopolymyositis	0.709	0.291	0.000
M00-M03 Infectious arthropathies	0.708	0.292	0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.707	0.293	0.000
M77 Other enthesopathies	0.707	0.293	0.000
M60-M63 Disorders of muscles	0.706	0.294	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.705	0.295	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.703	0.297	0.000
M19.8 Other specified arthrosis	0.702	0.298	0.000
M19.2 Other secondary arthrosis	0.702	0.298	0.000
M25.2 Flail joint	0.701	0.299	0.000
M25.1 Fistula of joint	0.701	0.299	0.000
M75.9 Shoulder lesion, unspecified	0.697	0.303	0.000
M43.0 Spondylolysis	0.695	0.305	0.000
M19.96 Arthrosis, unspecified-Lower leg	0.694	0.306	0.000
M43.12 Spondylolisthesis (Cervical region)	0.693	0.307	0.000
M40 Kyphosis and lordosis	0.688	0.312	0.000
M75.4 Impingement syndrome of shoulder	0.687	0.313	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.685	0.315	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.684	0.316	0.000
M16.5 Other posttraumatic coxarthrosis	0.684	0.316	0.000
M24.0 Loose body in joint	0.680	0.320	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.680	0.320	0.000
M41.9 Scoliosis, unspecified	0.679	0.321	0.000
M42 Spinal osteochondrosis	0.677	0.322	0.000
M21.9 Acquired deformity of limb, unspecified	0.675	0.325	0.000
M21.8 Other specified acquired deformities of limbs	0.675	0.325	0.000
M21.7 Unequal limb length (acquired)	0.675	0.325	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.674	0.326	0.000
M19.92 Arthrosis, unspecified (Upper arm)	0.668	0.332	0.000
M19.02 Primary arthrosis of other joints (Upper arm)	0.668	0.332	0.000
M70.2 Olecranon bursitis	0.666	0.334	0.000
M16.0 Primary coxarthrosis, bilateral	0.665	0.335	0.000
M25.49 Effusion of joint (Site unspecified)	0.664	0.335	0.000
M25.48 Effusion of joint (Other)	0.664	0.335	0.000
M25.43 Effusion of joint (Forearm)	0.664	0.335	0.000
M25.42 Effusion of joint (Upper arm)	0.664	0.335	0.000
M25.41 Effusion of joint (Shoulder region)	0.664	0.335	0.000
M25.40 Effusion of joint (Multiple sites)	0.664	0.335	0.000
M25.7 Osteophyte	0.658	0.342	0.000
M81 Osteoporosis without pathological fracture	0.655	0.345	0.000
M19.08 Primary arthrosis of other joints (Other)	0.650	0.350	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.650	0.350	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.650	0.350	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.648	0.352	0.000
M77.4 Metatarsalgia	0.648	0.352	0.000
M43.6 Torticollis	0.648	0.352	0.000
M24.2 Disorder of ligament	0.647	0.353	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.645	0.355	0.000
M25.06 Haemarthrosis (Lower leg)	0.643	0.357	0.000
M16.6 Other secondary coxarthrosis, bilateral	0.641	0.358	0.000
M16.4 Posttraumatic coxarthrosis, bilateral	0.641	0.358	0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.641	0.358	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.640	0.360	0.000
M34.0 Progressive systemic sclerosis	0.640	0.360	0.000
M21.29 Flexion deformity (Site unspecified)	0.640	0.360	0.000
M21.28 Flexion deformity (Other)	0.640	0.360	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.640	0.360	0.000
M21.23 Flexion deformity (Forearm)	0.640	0.360	0.000
M21.22 Flexion deformity (Upper arm)	0.640	0.360	0.000
M21.21 Flexion deformity (Shoulder region)	0.640	0.360	0.000
M21.20 Flexion deformity (Multiple sites)	0.640	0.360	0.000
M65-M68 Disorders of synovium and tendon	0.640	0.360	0.000
M25.31 Other instability of joint (Shoulder region)	0.639	0.361	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.639	0.361	0.000
M80 Osteoporosis with pathological fracture	0.639	0.361	0.000
M43.9 Deforming dorsopathy, unspecified	0.638	0.362	0.000
M43.8 Other specified deforming dorsopathies	0.638	0.362	0.000
M43.5 Other recurrent vertebral subluxation	0.638	0.362	0.000
M43.4 Other recurrent atlantoaxial subluxation	0.638	0.362	0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.638	0.362	0.000
M43.2 Other fusion of spine	0.638	0.362	0.000
M25.58 Pain in joint (Other)	0.635	0.365	0.000
M76 Enthesopathies of lower limb, excluding foot	0.634	0.366	0.000
M25.33 Other instability of joint (Forearm)	0.633	0.367	0.000
M30.0 Polyarteritis nodosa	0.630	0.370	0.000
M21.4 Flat foot [pes planus] (acquired)	0.627	0.373	0.000
M94 Other disorders of cartilage	0.626	0.374	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.625	0.375	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.625	0.375	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.625	0.375	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.625	0.375	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.624	0.376	0.000
M31 Other necrotising vasculopathies	0.621	0.379	0.000
M19.91 Arthrosis, unspecified (Shoulder region)	0.619	0.381	0.000
M89 Other disorders of bone	0.618	0.382	0.000
M34.1 CR(E)ST syndrome	0.618	0.382	0.000
M25.36 Other instability of joint (Lower leg)	0.616	0.384	0.000
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.613	0.387	0.000
M75.8 Other shoulder lesions	0.611	0.388	0.000
M25.50 Pain in joint (Multiple sites)	0.608	0.392	0.000
M16.3 Other dysplastic coxarthrosis	0.606	0.394	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.606	0.394	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.606	0.394	0.000
M85 Other disorders of bone density and structure	0.600	0.400	0.000
M43.19 Spondylolisthesis (Site unspecified)	0.600	0.400	0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.600	0.400	0.000
M43.15 Spondylolisthesis (Thoracolumbar region)	0.600	0.400	0.000
M43.14 Spondylolisthesis (Thoracic region)	0.600	0.400	0.000
M43.13 Spondylolisthesis (Cervicothoracic region)	0.600	0.400	0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.600	0.400	0.000
M43.10 Spondylolisthesis (Multiple sites in spine)	0.600	0.400	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.599	0.401	0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.596	0.403	0.000
M25.34 Other instability of joint (Hand)	0.590	0.410	0.000
M70.5 Other bursitis of knee	0.588	0.411	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.588	0.411	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.588	0.411	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.588	0.411	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.588	0.411	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.588	0.411	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.588	0.411	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.588	0.411	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.588	0.411	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.588	0.411	0.000
M25.8 Other specified joint disorders	0.588	0.412	0.000
M05-M14 Inflammatory polyarthropathies	0.588	0.412	0.000
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure	0.587	0.413	0.000
M70.8 Other soft tissue disorders related to use, overuse and pressure	0.587	0.413	0.000
M70.7 Other bursitis of hip	0.587	0.413	0.000
M70.3 Other bursitis of elbow	0.587	0.413	0.000
M70.1 Bursitis of hand	0.587	0.413	0.000
M70.0 Chronic crepitant synovitis of hand and wrist	0.587	0.413	0.000
M25.52 Pain in joint (Upper arm)	0.587	0.413	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.586	0.414	0.000
M50-M54 Other dorsopathies	0.583	0.417	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.583	0.417	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.582	0.418	0.000
M99 Biomechanical lesions, not elsewhere classified	0.582	0.418	0.000
M25.94 Joint disorder, unspecified (Hand)	0.578	0.422	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.577	0.422	0.000
M32.8 Other forms of systemic lupus erythematosus	0.577	0.422	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.577	0.422	0.000
M25.39 Other instability of joint (Site unspecified)	0.576	0.424	0.000
M25.38 Other instability of joint (Other)	0.576	0.424	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.576	0.424	0.000
M25.32 Other instability of joint (Upper arm)	0.576	0.424	0.000
M25.30 Other instability of joint (Multiple sites)	0.576	0.424	0.000
M43.06 Spondylolysis (Lumbar region)	0.575	0.425	0.000
M82 Osteoporosis in diseases classified elsewhere	0.572	0.428	0.000
M83 Adult osteomalacia	0.571	0.428	0.000
M24.07 Loose body in joint (Ankle and foot)	0.571	0.429	0.000
M24.9 Joint derangement, unspecified	0.570	0.430	0.000
M24.7 Protrusio acetabuli	0.570	0.430	0.000
M24.6 Ankylosis of joint	0.570	0.430	0.000
M41.8 Other forms of scoliosis	0.566	0.433	0.000
M41.5 Other secondary scoliosis	0.566	0.433	0.000
M41.4 Neuromuscular scoliosis	0.566	0.433	0.000
M41.3 Thoracogenic scoliosis	0.566	0.433	0.000
M41.2 Other idiopathic scoliosis	0.566	0.433	0.000
M41.1 Juvenile idiopathic scoliosis	0.566	0.433	0.000
M41.0 Infantile idiopathic scoliosis	0.566	0.433	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.565	0.435	0.000
M93 Other osteochondropathies	0.564	0.436	0.000
M25.76 Osteophyte (Lower leg)	0.563	0.437	0.000
M86 Osteomyelitis	0.563	0.437	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.562	0.438	0.000
M25.09 Haemarthrosis (Site unspecified)	0.561	0.438	0.000
M25.08 Haemarthrosis (Other)	0.561	0.438	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.561	0.438	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.561	0.438	0.000
M25.04 Haemarthrosis (Hand)	0.561	0.438	0.000
M25.03 Haemarthrosis (Forearm)	0.561	0.438	0.000
M25.02 Haemarthrosis (Upper arm)	0.561	0.438	0.000
M25.01 Haemarthrosis (Shoulder region)	0.561	0.438	0.000
M25.00 Haemarthrosis (Multiple sites)	0.561	0.438	0.000
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.560	0.439	0.000
M19.18 Post-traumatic arthrosis of other joints (Other)	0.560	0.439	0.000
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.560	0.439	0.000
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.560	0.439	0.000
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.560	0.439	0.000
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.560	0.439	0.000
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.560	0.439	0.000
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.560	0.439	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.560	0.440	0.000
M21.1 Varus deformity, not elsewhere classified	0.559	0.441	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.558	0.441	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.558	0.441	0.000
M30.2 Juvenile polyarteritis	0.558	0.441	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.558	0.442	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.557	0.443	0.000
M70.22 Olecranon bursitis-Upper arm	0.556	0.444	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.556	0.444	0.000
M75.3 Calcific tendinitis of shoulder	0.555	0.445	0.000
M92 Other juvenile osteochondrosis	0.555	0.445	0.000
M21.3 Wrist or foot drop (acquired)	0.554	0.446	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.554	0.446	0.000
M25.47 Effusion of joint (Ankle and foot)	0.553	0.447	0.000
M81.9 Osteoporosis, unspecified	0.548	0.452	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.547	0.453	0.000
M75.1 Rotator cuff syndrome	0.545	0.455	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.543	0.457	0.000
M60 Myositis	0.541	0.458	0.000
M70.69 Trochanteric bursitis-Site unspec	0.540	0.460	0.000
M70.68 Trochanteric bursitis-Other	0.540	0.460	0.000
M70.67 Trochanteric bursitis-Ankle/Foot	0.540	0.460	0.000
M70.66 Trochanteric bursitis-Lower Leg	0.540	0.460	0.000
M70.64 Trochanteric bursitis-Hand	0.540	0.460	0.000
M70.63 Trochanteric bursitis-Forearm	0.540	0.460	0.000
M70.62 Trochanteric bursitis-Upper arm	0.540	0.460	0.000
M70.61 Trochanteric bursitis-Shldr region	0.540	0.460	0.000
M70.60 Trochanteric bursitis-Mult sites	0.540	0.460	0.000
M15.1 Heberden's nodes (with arthropathy)	0.539	0.460	0.000
M24.26 Disorder of ligament (Lower leg)	0.538	0.462	0.000
M72 Fibroblastic disorders	0.537	0.463	0.000
M89.8 Other specified disorders of bone	0.537	0.463	0.000
M24.02 Loose body in joint (Upper arm)	0.535	0.465	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.534	0.466	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.530	0.469	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.530	0.469	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.530	0.469	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.530	0.469	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.530	0.469	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.530	0.469	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.530	0.469	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.530	0.469	0.000
M25.57 Pain in joint (Ankle and foot)	0.529	0.471	0.000
M20.1 Hallux valgus (acquired)	0.528	0.472	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.523	0.477	0.000
M25.98 Joint disorder, unspecified (Other)	0.523	0.477	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.523	0.477	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.523	0.477	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.523	0.477	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.523	0.477	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.523	0.477	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.523	0.477	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.523	0.477	0.000
M15.9 Polyarthrosis, unspecified	0.520	0.479	0.000
M15.0 Primary generalised (osteo)arthrosis	0.520	0.479	0.000
M15.8 Other polyarthrosis	0.520	0.479	0.000
M15.4 Erosive (osteo)arthrosis	0.520	0.479	0.000
M15.3 Secondary multiple arthrosis	0.520	0.479	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.520	0.479	0.000
M71 Other bursopathies	0.520	0.480	0.000
M16.7 Other secondary coxarthrosis	0.518	0.482	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.518	0.482	0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.517	0.483	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.517	0.483	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.517	0.483	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.517	0.483	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.517	0.483	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.517	0.483	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.517	0.483	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.517	0.483	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.517	0.483	0.000
M66 Spontaneous rupture of synovium and tendon	0.517	0.483	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.515	0.485	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.515	0.485	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.515	0.485	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.515	0.485	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.515	0.485	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.515	0.485	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.514	0.486	0.000
M90 Osteopathies in diseases classified elsewhere	0.514	0.486	0.000
M51 Other intervertebral disk disorders	0.514	0.486	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.513	0.487	0.000
M85.8 Other specified disorders of bone density and structure	0.510	0.490	0.000
M87 Osteonecrosis	0.509	0.491	0.000
M33.9 Dermatopolymyositis, unspecified	0.508	0.492	0.000
M33.2 Polymyositis	0.508	0.492	0.000
M33.1 Other dermatomyositis	0.508	0.492	0.000
M33.0 Juvenile dermatomyositis	0.508	0.492	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.508	0.492	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.508	0.492	0.000
M36.3 Arthropathy in other blood disorders	0.508	0.492	0.000
M36.2 Haemophilic arthropathy	0.508	0.492	0.000
M36.1 Arthropathy in neoplastic disease	0.508	0.492	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.508	0.492	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.508	0.492	0.000
M02 Reactive arthropathies	0.508	0.492	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.508	0.492	0.000
M00 Pyogenic arthritis	0.507	0.492	0.000
M77.8 Other enthesopathies, not elsewhere classified	0.507	0.493	0.000
M77.5 Other enthesopathy of foot	0.507	0.493	0.000
M77.3 Calcaneal spur	0.507	0.493	0.000
M77.2 Periarthritis of wrist	0.507	0.493	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.506	0.494	0.000
M61 Calcification and ossification of muscle	0.506	0.494	0.000
M24.5 Contracture of joint	0.506	0.494	0.000
M40.2 Other and unspecified kyphosis	0.504	0.495	0.000
M19.29 Other secondary arthrosis (Site unspecified)	0.503	0.497	0.000
M19.28 Other secondary arthrosis (Other)	0.503	0.497	0.000
M19.27 Other secondary arthrosis (Ankle and foot)	0.503	0.497	0.000
M19.26 Other secondary arthrosis of other joints-Lower leg	0.503	0.497	0.000
M19.25 Other secondary arthrosis (Pelvic region and thigh)	0.503	0.497	0.000
M19.24 Other secondary arthrosis (Hand)	0.503	0.497	0.000
M19.23 Other secondary arthrosis (Forearm)	0.503	0.497	0.000
M19.22 Other secondary arthrosis (Upper arm)	0.503	0.497	0.000
M19.21 Other secondary arthrosis (Shoulder region)	0.503	0.497	0.000
M19.20 Other secondary arthrosis (Multiple sites)	0.503	0.497	0.000
M19.89 Other specified arthrosis (Site unspecified)	0.503	0.497	0.000
M19.88 Other specified arthrosis (Other)	0.503	0.497	0.000
M19.87 Other specified arthrosis (Ankle and foot)	0.503	0.497	0.000
M19.86 Other specified arthrosis (Lower leg)	0.503	0.497	0.000
M19.85 Other specified arthrosis (Pelvic region and thigh)	0.503	0.497	0.000
M19.84 Other specified arthrosis (Hand)	0.503	0.497	0.000
M19.83 Other specified arthrosis (Forearm)	0.503	0.497	0.000
M19.82 Other specified arthrosis (Upper arm)	0.503	0.497	0.000
M19.81 Other specified arthrosis (Shoulder region)	0.503	0.497	0.000
M19.80 Other specified arthrosis (Multiple sites)	0.503	0.497	0.000
M25.19 Fistula of joint (Site unspecified)	0.503	0.497	0.000
M25.18 Fistula of joint (Other)	0.503	0.497	0.000
M25.17 Fistula of joint (Ankle and foot)	0.503	0.497	0.000
M25.16 Fistula of joint (Lower leg)	0.503	0.497	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.503	0.497	0.000
M25.14 Fistula of joint (Hand)	0.503	0.497	0.000
M25.13 Fistula of joint (Forearm)	0.503	0.497	0.000
M25.12 Fistula of joint (Upper arm)	0.503	0.497	0.000
M25.11 Fistula of joint (Shoulder region)	0.503	0.497	0.000
M25.10 Fistula of joint (Multiple sites)	0.503	0.497	0.000
M25.29 Flail joint (Site unspecified)	0.503	0.497	0.000
M25.28 Flail joint (Other)	0.503	0.497	0.000
M25.27 Flail joint (Ankle and foot)	0.503	0.497	0.000
M25.26 Flail joint (Lower leg)	0.503	0.497	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.503	0.497	0.000
M25.24 Flail joint (Hand)	0.503	0.497	0.000
M25.23 Flail joint (Forearm)	0.503	0.497	0.000
M25.22 Flail joint (Upper arm)	0.503	0.497	0.000
M25.21 Flail joint (Shoulder region)	0.503	0.497	0.000
M25.20 Flail joint (Multiple sites)	0.503	0.497	0.000
M80.8 Other osteoporosis with pathological fracture	0.503	0.497	0.000
M25.37 Other instability of joint (Ankle and foot)	0.503	0.497	0.000
M43.09 Spondylolysis (Site unspecified)	0.498	0.502	0.000
M43.08 Spondylolysis (Sacral and sacrococcygeal region)	0.498	0.502	0.000
M43.07 Spondylolysis (Lumbosacral region)	0.498	0.502	0.000
M43.05 Spondylolysis (Thoracolumbar region)	0.498	0.502	0.000
M43.04 Spondylolysis (Thoracic region)	0.498	0.502	0.000
M43.03 Spondylolysis (Cervicothoracic region)	0.498	0.502	0.000
M43.01 Spondylolysis (Occipito-atlanto-axial region)	0.498	0.502	0.000
M43.00 Spondylolysis (Multiple sites in spine)	0.498	0.502	0.000
M31.9 Necrotising vasculopathy, unspecified	0.498	0.502	0.000
M24.23 Disorder of ligament (Forearm)	0.498	0.502	0.000
M25.77 Osteophyte (Ankle and foot)	0.497	0.503	0.000
M10 Gout	0.496	0.504	0.000
M40.5 Lordosis, unspecified	0.494	0.506	0.000
M40.4 Other lordosis	0.494	0.506	0.000
M40.3 Flatback syndrome	0.494	0.506	0.000
M40.1 Other secondary kyphosis	0.494	0.506	0.000
M40.0 Postural kyphosis	0.494	0.506	0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.491	0.509	0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.491	0.509	0.000
M96.5 Postradiation scoliosis	0.491	0.509	0.000
M96.4 Postsurgical lordosis	0.491	0.509	0.000
M96.3 Postlaminectomy kyphosis	0.491	0.509	0.000
M96.2 Postradiation kyphosis	0.491	0.509	0.000
M70.4 Prepatellar bursitis	0.490	0.509	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.488	0.512	0.000
M24.09 Loose body in joint (Site unspecified)	0.488	0.512	0.000
M24.08 Loose body in joint (Other)	0.488	0.512	0.000
M24.06 Loose body in joint-Lower leg	0.488	0.512	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.488	0.512	0.000
M24.04 Loose body in joint (Hand)	0.488	0.512	0.000
M24.03 Loose body in joint (Forearm)	0.488	0.512	0.000
M24.01 Loose body in joint (Shoulder region)	0.488	0.512	0.000
M24.00 Loose body in joint (Multiple sites)	0.488	0.512	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.487	0.513	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.487	0.513	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.487	0.513	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.487	0.513	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.487	0.513	0.000
M42.9 Spinal osteochondrosis, unspecified	0.486	0.514	0.000
M42.1 Adult osteochondrosis of spine	0.486	0.514	0.000
M42.0 Juvenile osteochondrosis of spine	0.486	0.514	0.000
M21.79 Unequal limb length (acquired) (Site unspecified)	0.484	0.516	0.000
M21.78 Unequal limb length (acquired)-Other	0.484	0.516	0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.484	0.516	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.484	0.516	0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.484	0.516	0.000
M21.74 Unequal limb length (acquired) (Hand)	0.484	0.516	0.000
M21.73 Unequal limb length (acquired) (Forearm)	0.484	0.516	0.000
M21.72 Unequal limb length (acquired) (Upper arm)	0.484	0.516	0.000
M21.71 Unequal limb length (acquired)-Shldr region	0.484	0.516	0.000
M21.70 Unequal limb length (acquired) (Multiple sites)	0.484	0.516	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.484	0.516	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.484	0.516	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.484	0.516	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.484	0.516	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.484	0.516	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.484	0.516	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.484	0.516	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.484	0.516	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.484	0.516	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.484	0.516	0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.484	0.516	0.000
M21.98 Acquired deformity of limb, unspecified-Other	0.484	0.516	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.484	0.516	0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.484	0.516	0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.484	0.516	0.000
M21.94 Acquired deformity of limb, unspecified (Hand)	0.484	0.516	0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.484	0.516	0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.484	0.516	0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.484	0.516	0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.484	0.516	0.000
M22 Disorders of patella	0.480	0.520	0.000
M88 Paget's disease of bone [osteitis deformans]	0.480	0.520	0.000
M81.4 Drug-induced osteoporosis	0.480	0.520	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.479	0.521	0.000
M20.2 Hallux rigidus	0.479	0.521	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.478	0.522	0.000
M70.29 Olecranon bursitis-Site unspec	0.477	0.523	0.000
M70.28 Olecranon bursitis-Other	0.477	0.523	0.000
M70.27 Olecranon bursitis-Ankle/Foot	0.477	0.523	0.000
M70.26 Olecranon bursitis-Lower Leg	0.477	0.523	0.000
M70.25 Olecranon bursitis-Pelvic/Thigh	0.477	0.523	0.000
M70.24 Olecranon bursitis-Hand	0.477	0.523	0.000
M70.23 Olecranon bursitis-Forearm	0.477	0.523	0.000
M70.21 Olecranon bursitis-Shldr region	0.477	0.523	0.000
M70.20 Olecranon bursitis-Mult sites	0.477	0.523	0.000
M94.2 Chondromalacia	0.476	0.523	0.000
M94.9 Disorder of cartilage, unspecified	0.476	0.524	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.475	0.525	0.000
M43.62 Torticollis-Cervical	0.474	0.526	0.000
M77.0 Medial epicondylitis	0.473	0.527	0.000
M94.8 Other specified disorders of cartilage	0.473	0.527	0.000
M07 Psoriatic and enteropathic arthropathies	0.472	0.528	0.000
M25.79 Osteophyte (Site unspecified)	0.472	0.528	0.000
M25.73 Osteophyte (Forearm)	0.472	0.528	0.000
M25.70 Osteophyte (Multiple sites)	0.472	0.528	0.000
M89.0 Algoneurodystrophy	0.471	0.529	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.470	0.530	0.000
M81.8 Other osteoporosis	0.470	0.530	0.000
M81.6 Localised osteoporosis [Lequesne]	0.470	0.530	0.000
M81.5 Idiopathic osteoporosis	0.470	0.530	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.470	0.530	0.000
M81.2 Osteoporosis of disuse	0.470	0.530	0.000
M81.1 Postoophorectomy osteoporosis	0.470	0.530	0.000
M81.0 Postmenopausal osteoporosis	0.470	0.530	0.000
M25.54 Pain in joint (Hand)	0.470	0.530	0.000
M43.02 Spondylolysis (Cervical region)	0.466	0.534	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.465	0.535	0.000
M73.8 Other soft tissue disorders in diseases classified elsewhere	0.465	0.535	0.000
M73.1 Syphilitic bursitis	0.465	0.535	0.000
M73.0 Gonococcal bursitis	0.465	0.535	0.000
M77.49 Metatarsalgia-Site unspec	0.465	0.535	0.000
M77.48 Metatarsalgia-Other	0.465	0.535	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations