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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1596724
log Bayes Factor = 2.76067
Chromosome 4   position 32,555,853  (GRCh37) Explore rs1596724 on Ensembl!
Variant rs1596724 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
0.998 0.002 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.997 0.003 0.000
# Top node
0.994 0.006 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.983 0.017 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.981 0.019 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.972 0.028 0.000
Chapter XXI Factors influencing health status and contact with health services
0.968 0.032 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.962 0.038 0.000
D10-D36 Benign neoplasms
0.956 0.044 0.000
Z37 Outcome of delivery
0.948 0.052 0.000
O60-O75 Complications of labour and delivery
0.943 0.057 0.000
Z37.0 Single live birth
0.938 0.062 0.000
C15-C26 Malignant neoplasms of digestive organs
0.937 0.063 0.000
C79 Secondary malignant neoplasm of other sites
0.932 0.068 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.928 0.072 0.000
C77.2 Intra-abdominal lymph nodes
0.916 0.084 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.898 0.102 0.000
Chapter I Certain infectious and parasitic diseases
0.889 0.111 0.000
Z35 Supervision of high-risk pregnancy
0.887 0.113 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.884 0.116 0.000
A30-A49 Other bacterial diseases
0.873 0.127 0.000
O63 Long labour
0.872 0.128 0.000
S60-S69 Injuries to the wrist and hand
0.871 0.129 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.867 0.133 0.000
C44 Other malignant neoplasms of skin
0.865 0.135 0.000
C77.5 Intrapelvic lymph nodes
0.857 0.143 0.000
A41 Other septicaemia
0.851 0.149 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.846 0.154 0.000
Z46 Fitting and adjustment of other devices
0.845 0.155 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.843 0.157 0.000
D23 Other benign neoplasms of skin
0.842 0.158 0.000
S80-S89 Injuries to the knee and lower leg
0.841 0.159 0.000
C78.7 Secondary malignant neoplasm of liver
0.840 0.160 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.835 0.165 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.834 0.166 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.833 0.167 0.000
C77.4 Inguinal and lower limb lymph nodes
0.830 0.170 0.000
Z46.6 Fitting and adjustment of urinary device
0.825 0.175 0.000
D17 Benign lipomatous neoplasm
0.824 0.176 0.000
C77.1 Intrathoracic lymph nodes
0.822 0.178 0.000
A41.9 Septicaemia, unspecified
0.821 0.179 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.819 0.181 0.000
Z34 Supervision of normal pregnancy
0.812 0.188 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.812 0.188 0.000
T66-T78 Other and unspecified effects of external causes
0.810 0.190 0.000
O63.1 Prolonged second stage (of labour)
0.810 0.190 0.000
D27 Benign neoplasm of ovary
0.805 0.195 0.000
O00-O08 Pregnancy with abortive outcome
0.804 0.196 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.802 0.198 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.799 0.201 0.000
Chapter XIV Diseases of the genitourinary system
0.799 0.201 0.000
C44.3 Skin of other and unspecified parts of face
0.795 0.205 0.000
Chapter VIII Diseases of the ear and mastoid process
0.793 0.207 0.000
C15 Malignant neoplasm of oesophagus
0.790 0.210 0.000
C51-C58 Malignant neoplasms of female genital organs
0.784 0.216 0.000
C44.7 Skin of lower limb, including hip
0.783 0.217 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.782 0.218 0.000
C80 Malignant neoplasm without specification of site
0.778 0.222 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.772 0.228 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.771 0.229 0.000
Z35.5 Supervision of elderly primigravida
0.766 0.234 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.759 0.241 0.000
C16 Malignant neoplasm of stomach
0.756 0.244 0.000
Z39 Postpartum care and examination
0.755 0.245 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.754 0.246 0.000
Z36 Antenatal screening
0.754 0.246 0.000
O16 Unspecified maternal hypertension
0.752 0.248 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.750 0.250 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.749 0.251 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.748 0.252 0.000
S50-S59 Injuries to the elbow and forearm
0.747 0.253 0.000
N17-N19 Renal failure
0.743 0.257 0.000
A49 Bacterial infection of unspecified site
0.740 0.260 0.000
S90-S99 Injuries to the ankle and foot
0.740 0.260 0.000
Z35.0 Supervision of pregnancy with history of infertility
0.736 0.264 0.000
Chapter XXII Codes for special purposes
0.735 0.265 0.000
S70-S79 Injuries to the hip and thigh
0.735 0.265 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.732 0.268 0.000
Chapter V Mental and behavioural disorders
0.729 0.271 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.724 0.276 0.000
D32 Benign neoplasm of meninges
0.724 0.276 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.722 0.277 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.721 0.279 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.719 0.281 0.000
C77.0 Lymph nodes of head, face and neck
0.717 0.283 0.000
C43 Malignant melanoma of skin
0.717 0.283 0.000
D23.6 Skin of upper limb, including shoulder
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.716 0.284 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.716 0.284 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.715 0.285 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.715 0.285 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.713 0.287 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.713 0.287 0.000
O64.1 Obstructed labour due to breech presentation
0.712 0.287 0.000
D18 Haemangioma and lymphangioma, any site
0.712 0.288 0.000
N60-N64 Disorders of breast
0.712 0.288 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.712 0.288 0.000
D36 Benign neoplasm of other and unspecified sites
0.712 0.288 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.710 0.290 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.709 0.290 0.000
Z37.2 Twins, both liveborn
0.707 0.292 0.000
S20-S29 Injuries to the thorax
0.707 0.293 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.706 0.294 0.000
O85-O92 Complications predominantly related to the puerperium
0.705 0.295 0.000
S62 Fracture at wrist and hand level
0.704 0.296 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.704 0.296 0.000
C77.8 Lymph nodes of multiple regions
0.704 0.296 0.000
Z53.9 Procedure not carried out, unspecified reason
0.703 0.297 0.000
N10-N16 Renal tubulo-interstitial diseases
0.703 0.297 0.000
O70 Perineal laceration during delivery
0.699 0.301 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.698 0.302 0.000
C18 Malignant neoplasm of colon
0.698 0.302 0.000
Z60 Problems related to social environment
0.698 0.302 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.697 0.303 0.000
T79-T79 Certain early complications of trauma
0.697 0.303 0.000
T33-T35 Frostbite
0.697 0.303 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.697 0.303 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.697 0.303 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.697 0.303 0.000
T00-T07 Injuries involving multiple body regions
0.697 0.303 0.000
S10-S19 Injuries to the neck
0.697 0.303 0.000
O66 Other obstructed labour
0.697 0.303 0.000
C77.9 Lymph node, unspecified
0.695 0.305 0.000
T78 Adverse effects, not elsewhere classified
0.694 0.306 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.693 0.307 0.000
D12.2 Ascending colon
0.692 0.308 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.692 0.308 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.692 0.308 0.000
D45 Polycythaemia vera
0.691 0.309 0.000
Z38 Liveborn infants according to place of birth
0.690 0.310 0.000
Z32 Pregnancy examination and test
0.690 0.310 0.000
Z31 Procreative management
0.690 0.310 0.000
D23.4 Skin of scalp and neck
0.689 0.311 0.000
Z34.0 Supervision of normal first pregnancy
0.688 0.312 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.687 0.313 0.000
S60 Superficial injury of wrist and hand
0.687 0.313 0.000
C20 Malignant neoplasm of rectum
0.686 0.314 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.685 0.315 0.000
D31 Benign neoplasm of eye and adnexa
0.685 0.315 0.000
D30 Benign neoplasm of urinary organs
0.685 0.315 0.000
D29 Benign neoplasm of male genital organs
0.685 0.315 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.685 0.315 0.000
D26 Other benign neoplasms of uterus
0.685 0.315 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.685 0.315 0.000
D19 Benign neoplasm of mesothelial tissue
0.685 0.315 0.000
D16 Benign neoplasm of bone and articular cartilage
0.685 0.315 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.685 0.315 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.685 0.315 0.000
D11 Benign neoplasm of major salivary glands
0.685 0.315 0.000
D10 Benign neoplasm of mouth and pharynx
0.685 0.315 0.000
D34 Benign neoplasm of thyroid gland
0.685 0.315 0.000
O72 Postpartum haemorrhage
0.685 0.315 0.000
Chapter XX External causes of morbidity and mortality
0.684 0.316 0.000
S81 Open wound of lower leg
0.683 0.317 0.000
Z37.9 Outcome of delivery unspecified
0.680 0.320 0.000
Z37.7 Other multiple births, all stillborn
0.680 0.320 0.000
Z37.6 Other multiple births, some liveborn
0.680 0.320 0.000
Z37.5 Other multiple births, all liveborn
0.680 0.320 0.000
Z37.4 Twins, both stillborn
0.680 0.320 0.000
Z37.3 Twins, one liveborn and one stillborn
0.680 0.320 0.000
Z37.1 Single stillbirth
0.680 0.320 0.000
Z49 Care involving dialysis
0.678 0.322 0.000
S82 Fracture of lower leg, including ankle
0.677 0.323 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.677 0.323 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.676 0.324 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.676 0.324 0.000
O74 Complications of anaesthesia during labour and delivery
0.676 0.324 0.000
O73 Retained placenta and membranes, without haemorrhage
0.676 0.324 0.000
O71 Other obstetric trauma
0.676 0.324 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.676 0.324 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.676 0.324 0.000
O62 Abnormalities of forces of labour
0.676 0.324 0.000
O61 Failed induction of labour
0.676 0.324 0.000
O60 Preterm delivery
0.676 0.324 0.000
N18 Chronic renal failure
0.674 0.326 0.000
Z35.1 Supervision of pregnancy with history of abortive outcome
0.672 0.328 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.672 0.328 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.672 0.328 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.672 0.328 0.000
C21 Malignant neoplasm of anus and anal canal
0.672 0.328 0.000
C17 Malignant neoplasm of small intestine
0.672 0.328 0.000
C23 Malignant neoplasm of gallbladder
0.672 0.328 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.671 0.329 0.000
O63.0 Prolonged first stage (of labour)
0.671 0.329 0.000
D12.5 Sigmoid colon
0.669 0.331 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.668 0.332 0.000
C79.6 Secondary malignant neoplasm of ovary
0.668 0.332 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.668 0.332 0.000
C79.2 Secondary malignant neoplasm of skin
0.668 0.332 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.668 0.332 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.668 0.332 0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history
0.667 0.333 0.000
R30-R39 Symptoms and signs involving the urinary system
0.666 0.334 0.000
S00-S09 Injuries to the head
0.665 0.335 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.665 0.335 0.000
C44.6 Skin of upper limb, including shoulder
0.664 0.336 0.000
C56 Malignant neoplasm of ovary
0.663 0.337 0.000
Z53.0 Procedure not carried out because of contraindication
0.662 0.338 0.000
S69 Other and unspecified injuries of wrist and hand
0.662 0.338 0.000
O47 False labour
0.661 0.339 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.660 0.340 0.000
D12.4 Descending colon
0.659 0.341 0.000
Z46.8 Fitting and adjustment of other specified devices
0.658 0.342 0.000
Z52 Donors of organs and tissues
0.656 0.344 0.000
O48 Prolonged pregnancy
0.655 0.345 0.000
Chapter VI Diseases of the nervous system
0.655 0.345 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.654 0.346 0.000
Z43 Attention to artificial openings
0.654 0.346 0.000
O02 Other abnormal products of conception
0.654 0.346 0.000
O36 Maternal care for other known or suspected foetal problems
0.653 0.347 0.000
C44.4 Skin of scalp and neck
0.651 0.349 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.650 0.350 0.000
C15.5 Lower third of oesophagus
0.650 0.350 0.000
D12.9 Anus and anal canal
0.648 0.352 0.000
C92 Myeloid leukaemia
0.647 0.353 0.000
R32 Unspecified urinary incontinence
0.646 0.354 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.645 0.355 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.645 0.355 0.000
D23.1 Skin of eyelid, including canthus
0.644 0.356 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.644 0.356 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.644 0.356 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.644 0.356 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.644 0.356 0.000
C77.3 Axillary and upper limb lymph nodes
0.642 0.358 0.000
O03 Spontaneous abortion
0.641 0.359 0.000
Z36.9 Antenatal screening, unspecified
0.640 0.360 0.000
S80 Superficial injury of lower leg
0.639 0.361 0.000
B99-B99 Other infectious diseases
0.637 0.362 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.637 0.362 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.637 0.362 0.000
B65-B83 Helminthiases
0.637 0.362 0.000
B50-B64 Protozoal diseases
0.637 0.362 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.637 0.362 0.000
B15-B19 Viral hepatitis
0.637 0.362 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.637 0.362 0.000
A80-A89 Viral infections of the central nervous system
0.637 0.362 0.000
A75-A79 Rickettsioses
0.637 0.362 0.000
A70-A74 Other diseases caused by chlamydiae
0.637 0.362 0.000
A65-A69 Other spirochaetal diseases
0.637 0.362 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.637 0.362 0.000
A20-A28 Certain zoonotic bacterial diseases
0.637 0.362 0.000
A15-A19 Tuberculosis
0.637 0.362 0.000
H65-H75 Diseases of middle ear and mastoid
0.637 0.363 0.000
D46 Myelodysplastic syndromes
0.636 0.364 0.000
Z35.9 Supervision of high-risk pregnancy, unspecified
0.636 0.364 0.000
Z35.8 Supervision of other high-risk pregnancies
0.636 0.364 0.000
Z35.7 Supervision of high-risk pregnancy due to social problems
0.636 0.364 0.000
Z35.6 Supervision of very young primigravida
0.636 0.364 0.000
Z35.4 Supervision of pregnancy with grand multiparity
0.636 0.364 0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care
0.636 0.364 0.000
D23.3 Skin of other and unspecified parts of face
0.635 0.365 0.000
O30 Multiple gestation
0.634 0.366 0.000
O15 Eclampsia
0.634 0.366 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.634 0.366 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.634 0.366 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.634 0.366 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.634 0.366 0.000
N13 Obstructive and reflux uropathy
0.634 0.366 0.000
Z40 Prophylactic surgery
0.632 0.368 0.000
C25 Malignant neoplasm of pancreas
0.631 0.369 0.000
D50-D53 Nutritional anaemias
0.631 0.369 0.000
C44.0 Skin of lip
0.630 0.370 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.629 0.371 0.000
C16.0 Cardia
0.627 0.373 0.000
Z45 Adjustment and management of implanted device
0.627 0.373 0.000
S40-S49 Injuries to the shoulder and upper arm
0.626 0.374 0.000
A48 Other bacterial diseases, not elsewhere classified
0.626 0.374 0.000
A44 Bartonellosis
0.626 0.374 0.000
A43 Nocardiosis
0.626 0.374 0.000
A42 Actinomycosis
0.626 0.374 0.000
A40 Streptococcal septicaemia
0.626 0.374 0.000
A39 Meningococcal infection
0.626 0.374 0.000
A37 Whooping cough
0.626 0.374 0.000
A36 Diphtheria
0.626 0.374 0.000
A32 Listeriosis
0.626 0.374 0.000
A31 Infection due to other mycobacteria
0.626 0.374 0.000
A30 Leprosy [Hansen's disease]
0.626 0.374 0.000
A46 Erysipelas
0.626 0.374 0.000
A38 Scarlet fever
0.626 0.374 0.000
A35 Other tetanus
0.626 0.374 0.000
A34 Obstetrical tetanus
0.626 0.374 0.000
A33 Tetanus neonatorum
0.626 0.374 0.000
O63.9 Long labour, unspecified
0.625 0.375 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.625 0.375 0.000
S67 Crushing injury of wrist and hand
0.624 0.375 0.000
S65 Injury of blood vessels at wrist and hand level
0.624 0.375 0.000
S64 Injury of nerves at wrist and hand level
0.624 0.375 0.000
S89 Other and unspecified injuries of lower leg
0.624 0.376 0.000
Z41 Procedures for purposes other than remedying health state
0.624 0.376 0.000
Z60.2 Living alone
0.623 0.377 0.000
C50-C50 Malignant neoplasm of breast
0.622 0.378 0.000
Z54 Convalescence
0.622 0.378 0.000
Z44 Fitting and adjustment of external prosthetic device
0.622 0.378 0.000
C43.5 Malignant melanoma of trunk
0.622 0.378 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.621 0.379 0.000
C80.9 Malignant neoplasm, unspecified
0.621 0.379 0.000
C15.9 Oesophagus, unspecified
0.621 0.379 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.621 0.379 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.620 0.380 0.000
C44.8 Overlapping lesion of skin
0.620 0.380 0.000
Q60-Q64 Congenital malformations of the urinary system
0.620 0.380 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.618 0.382 0.000
D00-D09 In situ neoplasms
0.616 0.383 0.000
C60-C63 Malignant neoplasms of male genital organs
0.616 0.384 0.000
N61 Inflammatory disorders of breast
0.616 0.384 0.000
A49.0 Staphylococcal infection, unspecified
0.615 0.384 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.615 0.385 0.000
Z34.8 Supervision of other normal pregnancy
0.612 0.388 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.611 0.388 0.000
T78.4 Allergy, unspecified
0.611 0.389 0.000
A41.8 Other specified septicaemia
0.610 0.390 0.000
A41.4 Septicaemia due to anaerobes
0.610 0.390 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.610 0.390 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.610 0.390 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.610 0.390 0.000
N19 Unspecified renal failure
0.610 0.390 0.000
S82.6 Fracture of lateral malleolus
0.607 0.393 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.606 0.393 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.606 0.393 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.606 0.393 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.606 0.393 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.606 0.393 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.606 0.393 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.606 0.393 0.000
F30-F39 Mood [affective] disorders
0.606 0.394 0.000
Z46.9 Fitting and adjustment of other unspecified device
0.606 0.394 0.000
Z46.7 Fitting and adjustment of orthopaedic device
0.606 0.394 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.606 0.394 0.000
Z46.4 Fitting and adjustment of orthodontic device
0.606 0.394 0.000
Z46.3 Fitting and adjustment of dental prosthetic device
0.606 0.394 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.606 0.394 0.000
Z46.1 Fitting and adjustment of hearing aid
0.606 0.394 0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses
0.606 0.394 0.000
O45 Premature separation of placenta [abruptio placentae]
0.604 0.396 0.000
O44 Placenta praevia
0.604 0.396 0.000
O43 Placental disorders
0.604 0.396 0.000
O41 Other disorders of amniotic fluid and membranes
0.604 0.396 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.604 0.396 0.000
O33 Maternal care for known or suspected disproportion
0.604 0.396 0.000
O31 Complications specific to multiple gestation
0.604 0.396 0.000
O40 Polyhydramnios
0.604 0.396 0.000
Q00-Q07 Congenital malformations of the nervous system
0.604 0.396 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.604 0.396 0.000
O00 Ectopic pregnancy
0.604 0.396 0.000
D23.9 Skin, unspecified
0.603 0.396 0.000
D23.2 Skin of ear and external auricular canal
0.603 0.396 0.000
D23.0 Skin of lip
0.603 0.396 0.000
S88 Traumatic amputation of lower leg
0.603 0.397 0.000
S87 Crushing injury of lower leg
0.603 0.397 0.000
S86 Injury of muscle and tendon at lower leg level
0.603 0.397 0.000
S85 Injury of blood vessels at lower leg level
0.603 0.397 0.000
S84 Injury of nerves at lower leg level
0.603 0.397 0.000
D21.2 Connective and other soft tissue of lower limb, including hip
0.602 0.398 0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder
0.599 0.401 0.000
Z42 Follow-up care involving plastic surgery
0.599 0.401 0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified
0.598 0.401 0.000
O64.8 Obstructed labour due to other malposition and malpresentation
0.598 0.401 0.000
O64.5 Obstructed labour due to compound presentation
0.598 0.401 0.000
O64.4 Obstructed labour due to shoulder presentation
0.598 0.401 0.000
O64.3 Obstructed labour due to brow presentation
0.598 0.401 0.000
O64.2 Obstructed labour due to face presentation
0.598 0.401 0.000
S50 Superficial injury of forearm
0.597 0.403 0.000
Z48 Other surgical follow-up care
0.597 0.403 0.000
D25 Leiomyoma of uterus
0.594 0.405 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.594 0.406 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.593 0.407 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.593 0.407 0.000
Z39.1 Care and examination of lactating mother
0.592 0.408 0.000
H90-H95 Other disorders of ear
0.591 0.409 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.591 0.409 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.591 0.409 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.590 0.410 0.000
B25-B34 Other viral diseases
0.589 0.411 0.000
N18.9 Chronic renal failure, unspecified
0.589 0.411 0.000
N62 Hypertrophy of breast
0.589 0.411 0.000
N99-N99 Other disorders of the genitourinary system
0.586 0.414 0.000
N00-N08 Glomerular diseases
0.585 0.415 0.000
D23.5 Skin of trunk
0.584 0.416 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.582 0.418 0.000
Chapter IX Diseases of the circulatory system
0.582 0.418 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.582 0.418 0.000
T87 Complications peculiar to reattachment and amputation
0.582 0.418 0.000
T86 Failure and rejection of transplanted organs and tissues
0.582 0.418 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.582 0.418 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.581 0.419 0.000
T75 Effects of other external causes
0.581 0.419 0.000
T74 Maltreatment syndromes
0.581 0.419 0.000
T73 Effects of other deprivation
0.581 0.419 0.000
T70 Effects of air pressure and water pressure
0.581 0.419 0.000
T69 Other effects of reduced temperature
0.581 0.419 0.000
T67 Effects of heat and light
0.581 0.419 0.000
T71 Asphyxiation
0.581 0.419 0.000
T68 Hypothermia
0.581 0.419 0.000
T66 Unspecified effects of radiation
0.581 0.419 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.581 0.419 0.000
D12.7 Rectosigmoid junction
0.580 0.420 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.580 0.420 0.000
A49.8 Other bacterial infections of unspecified site
0.580 0.420 0.000
R33 Retention of urine
0.579 0.421 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.579 0.421 0.000
C64-C68 Malignant neoplasms of urinary tract
0.578 0.422 0.000
B35-B49 Mycoses
0.578 0.422 0.000
O80-O84 Delivery
0.577 0.423 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.576 0.424 0.000
O07 Failed attempted abortion
0.576 0.424 0.000
O06 Unspecified abortion
0.576 0.424 0.000
O05 Other abortion
0.576 0.424 0.000
O01 Hydatidiform mole
0.576 0.424 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.576 0.424 0.000
C81 Hodgkin's disease
0.576 0.424 0.000
Z65 Problems related to other psychosocial circumstances
0.575 0.425 0.000
Z64 Problems related to certain psychosocial circumstances
0.575 0.425 0.000
Z63 Other problems related to primary support group, including family circumstances
0.575 0.425 0.000
Z62 Other problems related to upbringing
0.575 0.425 0.000
Z61 Problems related to negative life events in childhood
0.575 0.425 0.000
Z59 Problems related to housing and economic circumstances
0.575 0.425 0.000
Z58 Problems related to physical environment
0.575 0.425 0.000
Z56 Problems related to employment and unemployment
0.575 0.425 0.000
Z55 Problems related to education and literacy
0.575 0.425 0.000
H80-H83 Diseases of inner ear
0.573 0.427 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.573 0.427 0.000
Q80-Q89 Other congenital malformations
0.573 0.427 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.573 0.427 0.000
Q50-Q56 Congenital malformations of genital organs
0.573 0.427 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.573 0.427 0.000
Q35-Q37 Cleft lip and cleft palate
0.573 0.427 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.573 0.427 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.573 0.427 0.000
S91 Open wound of ankle and foot
0.573 0.427 0.000
D13.1 Stomach
0.572 0.428 0.000
N64 Other disorders of breast
0.572 0.428 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.571 0.429 0.000
S68 Traumatic amputation of wrist and hand
0.570 0.430 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.570 0.430 0.000
F80-F89 Disorders of psychological development
0.569 0.431 0.000
S81.0 Open wound of knee
0.569 0.431 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.569 0.431 0.000
S62.2 Fracture of first metacarpal bone
0.568 0.431 0.000
D51 Vitamin B12 deficiency anaemia
0.568 0.432 0.000
N60 Benign mammary dysplasia
0.566 0.434 0.000
C15.8 Overlapping lesion of oesophagus
0.566 0.434 0.000
C15.4 Middle third of oesophagus
0.566 0.434 0.000
C15.3 Upper third of oesophagus
0.566 0.434 0.000
C15.2 Abdominal part of oesophagus
0.566 0.434 0.000
C15.1 Thoracic part of oesophagus
0.566 0.434 0.000
C15.0 Cervical part of oesophagus
0.566 0.434 0.000
C91 Lymphoid leukaemia
0.566 0.434 0.000
S72 Fracture of femur
0.566 0.434 0.000
C44.5 Skin of trunk
0.564 0.436 0.000
D35.0 Adrenal gland
0.562 0.438 0.000
Z45.2 Adjustment and management of vascular access device
0.562 0.438 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.562 0.438 0.000
C53 Malignant neoplasm of cervix uteri
0.562 0.438 0.000
C51 Malignant neoplasm of vulva
0.562 0.438 0.000
C58 Malignant neoplasm of placenta
0.562 0.438 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.562 0.438 0.000
C52 Malignant neoplasm of vagina
0.562 0.438 0.000
D35.2 Pituitary gland
0.561 0.439 0.000
N25-N29 Other disorders of kidney and ureter
0.560 0.439 0.000
D12.1 Appendix
0.560 0.440 0.000
S01 Open wound of head
0.560 0.440 0.000
Z39.0 Care and examination immediately after delivery
0.560 0.440 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.559 0.441 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.558 0.442 0.000
D32.0 Cerebral meninges
0.558 0.442 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.558 0.442 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.558 0.442 0.000
S82.60 Fracture of lateral malleolus (closed)
0.557 0.443 0.000
H60-H62 Diseases of external ear
0.557 0.443 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.555 0.445 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.554 0.446 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.554 0.446 0.000
C95 Leukaemia of unspecified cell type
0.554 0.446 0.000
C94 Other leukaemias of specified cell type
0.554 0.446 0.000
C93 Monocytic leukaemia
0.554 0.446 0.000
C88 Malignant immunoproliferative diseases
0.554 0.446 0.000
C86 Other specified types of T/NK-cell lymphoma
0.554 0.446 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.554 0.446 0.000
D80-D89 Certain disorders involving the immune mechanism
0.553 0.447 0.000
D21.9 Connective and other soft tissue, unspecified
0.553 0.447 0.000
D21.6 Connective and other soft tissue of trunk, unspecified
0.553 0.447 0.000
D21.5 Connective and other soft tissue of pelvis
0.553 0.447 0.000
D21.4 Connective and other soft tissue of abdomen
0.553 0.447 0.000
D21.3 Connective and other soft tissue of thorax
0.553 0.447 0.000
D21.0 Connective and other soft tissue of head, face and neck
0.553 0.447 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.550 0.450 0.000
S61 Open wound of wrist and hand
0.548 0.451 0.000
N17 Acute renal failure
0.548 0.452 0.000
O70.1 Second degree perineal laceration during delivery
0.546 0.454 0.000
O02.1 Missed abortion
0.546 0.454 0.000
Z33 Pregnant state, incidental
0.545 0.455 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.544 0.456 0.000
T18 Foreign body in alimentary tract
0.544 0.456 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.543 0.457 0.000
F31 Bipolar affective disorder
0.542 0.458 0.000
C16.9 Stomach, unspecified
0.542 0.458 0.000
C16.8 Overlapping lesion of stomach
0.542 0.458 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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