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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1627851
log Bayes Factor = 16.6068
Chromosome 11   position 113,962,157  (GRCh37) Explore rs1627851 on Ensembl!
Variant rs1627851 is part of Cluster X0029

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter II Neoplasms
0.998 0.002 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.992 0.008 0.000
Chapter VI Diseases of the nervous system
0.992 0.008 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.989 0.011 0.000
I60-I69 Cerebrovascular diseases
0.987 0.013 0.000
Chapter X Diseases of the respiratory system
0.987 0.013 0.000
Chapter XXI Factors influencing health status and contact with health services
0.985 0.015 0.000
Chapter XX External causes of morbidity and mortality
0.981 0.019 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.975 0.025 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.974 0.026 0.000
J40-J47 Chronic lower respiratory diseases
0.973 0.027 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.971 0.029 0.000
I69 Sequelae of cerebrovascular disease
0.969 0.031 0.000
M20-M25 Other joint disorders
0.968 0.032 0.000
I80 Phlebitis and thrombophlebitis
0.966 0.034 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.964 0.036 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.963 0.037 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.963 0.037 0.000
J44 Other chronic obstructive pulmonary disease
0.962 0.038 0.000
M70-M79 Other soft tissue disorders
0.961 0.039 0.000
G81 Hemiplegia
0.958 0.042 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.951 0.049 0.000
Chapter V Mental and behavioural disorders
0.949 0.051 0.000
M25 Other joint disorders, not elsewhere classified
0.948 0.052 0.000
G81.9 Hemiplegia, unspecified
0.947 0.053 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.946 0.054 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.944 0.056 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.943 0.057 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.941 0.059 0.000
C78.7 Secondary malignant neoplasm of liver
0.941 0.059 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.937 0.063 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.929 0.071 0.000
M05-M14 Inflammatory polyarthropathies
0.929 0.071 0.000
G40-G47 Episodic and paroxysmal disorders
0.929 0.071 0.000
E00-E07 Disorders of thyroid gland
0.928 0.072 0.000
I69.3 Sequelae of cerebral infarction
0.928 0.072 0.000
I05-I09 Chronic rheumatic heart diseases
0.927 0.072 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.927 0.073 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.925 0.075 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.924 0.076 0.000
M25.5 Pain in joint
0.918 0.082 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.909 0.091 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.907 0.093 0.000
D00-D09 In situ neoplasms
0.902 0.098 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.900 0.100 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.900 0.100 0.000
Z51 Other medical care
0.899 0.101 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.895 0.105 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.894 0.106 0.000
M79.8 Other specified soft tissue disorders
0.888 0.112 0.000
J60-J70 Lung diseases due to external agents
0.885 0.115 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.879 0.121 0.000
Z47 Other orthopaedic follow-up care
0.878 0.122 0.000
I83 Varicose veins of lower extremities
0.878 0.122 0.000
C34 Malignant neoplasm of bronchus and lung
0.873 0.127 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.872 0.128 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.872 0.128 0.000
I67 Other cerebrovascular diseases
0.872 0.128 0.000
J09-J18 Influenza and pneumonia
0.871 0.129 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.871 0.129 0.000
M86-M90 Other osteopathies
0.870 0.130 0.000
E70-E90 Metabolic disorders
0.868 0.132 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.868 0.132 0.000
S60-S69 Injuries to the wrist and hand
0.865 0.135 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.865 0.135 0.000
Z50 Care involving use of rehabilitation procedures
0.864 0.136 0.000
Z42 Follow-up care involving plastic surgery
0.861 0.139 0.000
C15-C26 Malignant neoplasms of digestive organs
0.860 0.140 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.858 0.142 0.000
Z51.3 Blood transfusion without reported diagnosis
0.853 0.147 0.000
J90-J94 Other diseases of pleura
0.851 0.149 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.851 0.149 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.850 0.150 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.850 0.150 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.849 0.151 0.000
W00-W19 Falls
0.849 0.151 0.000
J40 Bronchitis, not specified as acute or chronic
0.845 0.155 0.000
Chapter I Certain infectious and parasitic diseases
0.844 0.156 0.000
E78.5 Hyperlipidaemia, unspecified
0.843 0.157 0.000
M80-M85 Disorders of bone density and structure
0.841 0.159 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.840 0.160 0.000
C78.0 Secondary malignant neoplasm of lung
0.839 0.161 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.839 0.161 0.000
D50-D53 Nutritional anaemias
0.839 0.161 0.000
F30-F39 Mood [affective] disorders
0.838 0.162 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.838 0.162 0.000
I84 Haemorrhoids
0.837 0.163 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.837 0.163 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.833 0.167 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.832 0.168 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.832 0.168 0.000
Z51.8 Other specified medical care
0.831 0.169 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.828 0.172 0.000
G70-G73 Diseases of myoneural junction and muscle
0.828 0.172 0.000
E04 Other non-toxic goitre
0.827 0.173 0.000
Z48 Other surgical follow-up care
0.827 0.173 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.826 0.174 0.000
Chapter XIV Diseases of the genitourinary system
0.826 0.174 0.000
S90-S99 Injuries to the ankle and foot
0.824 0.176 0.000
I77 Other disorders of arteries and arterioles
0.823 0.177 0.000
M77 Other enthesopathies
0.823 0.177 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.822 0.178 0.000
Z72 Problems related to lifestyle
0.821 0.179 0.000
I05 Rheumatic mitral valve diseases
0.819 0.180 0.000
Y83.6 Removal of other organ (partial) (total)
0.817 0.183 0.000
C78.2 Secondary malignant neoplasm of pleura
0.814 0.186 0.000
J69 Pneumonitis due to solids and liquids
0.813 0.187 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.813 0.187 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.810 0.190 0.000
Z73 Problems related to life-management difficulty
0.810 0.190 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.805 0.195 0.000
M91-M94 Chondropathies
0.804 0.196 0.000
D04 Carcinoma in situ of skin
0.804 0.196 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.803 0.197 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.803 0.197 0.000
J42 Unspecified chronic bronchitis
0.803 0.197 0.000
M06 Other rheumatoid arthritis
0.802 0.198 0.000
L89 Decubitus ulcer
0.802 0.198 0.000
J18 Pneumonia, organism unspecified
0.799 0.201 0.000
R42 Dizziness and giddiness
0.798 0.202 0.000
M13 Other arthritis
0.797 0.203 0.000
S40-S49 Injuries to the shoulder and upper arm
0.796 0.204 0.000
T90 Sequelae of injuries of head
0.793 0.207 0.000
T79-T79 Certain early complications of trauma
0.792 0.208 0.000
N10-N16 Renal tubulo-interstitial diseases
0.791 0.209 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.790 0.210 0.000
S62 Fracture at wrist and hand level
0.790 0.210 0.000
Z72.1 Alcohol use
0.789 0.211 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.789 0.211 0.000
G47 Sleep disorders
0.788 0.212 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.788 0.212 0.000
M79.6 Pain in limb
0.788 0.212 0.000
I72 Other aneurysm
0.787 0.213 0.000
M25.7 Osteophyte
0.783 0.217 0.000
I84.4 External haemorrhoids with other complications
0.781 0.219 0.000
I08 Multiple valve diseases
0.781 0.219 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.781 0.219 0.000
T66-T78 Other and unspecified effects of external causes
0.780 0.220 0.000
F01 Vascular dementia
0.780 0.220 0.000
T92 Sequelae of injuries of upper limb
0.779 0.221 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.778 0.222 0.000
M21 Other acquired deformities of limbs
0.778 0.222 0.000
J95-J99 Other diseases of the respiratory system
0.777 0.223 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.775 0.225 0.000
I67.9 Cerebrovascular disease, unspecified
0.774 0.226 0.000
G44 Other headache syndromes
0.773 0.227 0.000
S80-S89 Injuries to the knee and lower leg
0.771 0.229 0.000
I73 Other peripheral vascular diseases
0.771 0.229 0.000
M24 Other specific joint derangements
0.769 0.231 0.000
T86 Failure and rejection of transplanted organs and tissues
0.768 0.231 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.767 0.233 0.000
G43 Migraine
0.766 0.234 0.000
W20-W49 Exposure to inanimate mechanical forces
0.766 0.234 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.765 0.235 0.000
I61 Intracerebral haemorrhage
0.765 0.235 0.000
M25.50 Pain in joint (Multiple sites)
0.765 0.235 0.000
E10-E14 Diabetes mellitus
0.764 0.236 0.000
S50-S59 Injuries to the elbow and forearm
0.763 0.237 0.000
Y83.4 Other reconstructive surgery
0.763 0.237 0.000
I74 Arterial embolism and thrombosis
0.763 0.237 0.000
D50 Iron deficiency anaemia
0.762 0.238 0.000
I81 Portal vein thrombosis
0.762 0.238 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.762 0.238 0.000
Z74 Problems related to care-provider dependency
0.761 0.239 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.761 0.239 0.000
F80-F89 Disorders of psychological development
0.761 0.239 0.000
J69.0 Pneumonitis due to food and vomit
0.761 0.239 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.760 0.240 0.000
B25-B34 Other viral diseases
0.760 0.240 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.759 0.241 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.758 0.242 0.000
E07 Other disorders of thyroid
0.758 0.242 0.000
Z51.1 Chemotherapy session for neoplasm
0.756 0.244 0.000
I63 Cerebral infarction
0.755 0.245 0.000
N17-N19 Renal failure
0.753 0.247 0.000
D41.4 Bladder
0.751 0.249 0.000
M07 Psoriatic and enteropathic arthropathies
0.749 0.251 0.000
X50-X57 Overexertion, travel and privation
0.749 0.251 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.748 0.252 0.000
M31 Other necrotising vasculopathies
0.748 0.252 0.000
C34.3 Lower lobe, bronchus or lung
0.748 0.252 0.000
L82 Seborrhoeic keratosis
0.747 0.253 0.000
G82 Paraplegia and tetraplegia
0.746 0.253 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.746 0.254 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.746 0.254 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.746 0.254 0.000
M25.8 Other specified joint disorders
0.744 0.256 0.000
I84.9 Unspecified haemorrhoids without complication
0.743 0.257 0.000
N13 Obstructive and reflux uropathy
0.742 0.258 0.000
A30-A49 Other bacterial diseases
0.741 0.259 0.000
J18.1 Lobar pneumonia, unspecified
0.741 0.259 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.741 0.259 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.741 0.259 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.741 0.259 0.000
T85.2 Mechanical complication of intraocular lens
0.740 0.260 0.000
F03 Unspecified dementia
0.739 0.261 0.000
E05.9 Thyrotoxicosis, unspecified
0.739 0.261 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.738 0.262 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.738 0.262 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.738 0.262 0.000
D45 Polycythaemia vera
0.737 0.263 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.737 0.263 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.737 0.263 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.737 0.263 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.736 0.264 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.736 0.264 0.000
C34.1 Upper lobe, bronchus or lung
0.735 0.265 0.000
V80-V89 Other land transport accidents
0.735 0.265 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.735 0.265 0.000
R50-R69 General symptoms and signs
0.734 0.266 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.734 0.266 0.000
M00-M03 Infectious arthropathies
0.733 0.267 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.732 0.267 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.732 0.268 0.000
M22 Disorders of patella
0.732 0.268 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.732 0.268 0.000
Z50.5 Speech therapy
0.730 0.270 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.730 0.270 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.730 0.270 0.000
R47-R49 Symptoms and signs involving speech and voice
0.729 0.271 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.729 0.271 0.000
M15-M19 Arthrosis
0.729 0.271 0.000
R27 Other lack of coordination
0.729 0.271 0.000
D50.9 Iron deficiency anaemia, unspecified
0.729 0.271 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.728 0.272 0.000
L81 Other disorders of pigmentation
0.727 0.273 0.000
I26 Pulmonary embolism
0.727 0.273 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.727 0.273 0.000
D06 Carcinoma in situ of cervix uteri
0.726 0.274 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.726 0.274 0.000
Z51.5 Palliative care
0.726 0.274 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.725 0.275 0.000
M45-M49 Spondylopathies
0.725 0.275 0.000
E04.9 Non-toxic goitre, unspecified
0.725 0.275 0.000
T93 Sequelae of injuries of lower limb
0.724 0.276 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.724 0.276 0.000
G80 Infantile cerebral palsy
0.724 0.276 0.000
I77.1 Stricture of artery
0.723 0.277 0.000
I78 Diseases of capillaries
0.722 0.278 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.722 0.278 0.000
M71 Other bursopathies
0.721 0.279 0.000
I82 Other venous embolism and thrombosis
0.721 0.279 0.000
M23 Internal derangement of knee
0.721 0.279 0.000
Z73.3 Stress, not elsewhere classified
0.719 0.281 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.719 0.281 0.000
M87 Osteonecrosis
0.718 0.282 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.283 0.000
S10-S19 Injuries to the neck
0.716 0.283 0.000
L89.1 Stage II decubitus ulcer
0.716 0.284 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.715 0.285 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.715 0.285 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.715 0.285 0.000
N19 Unspecified renal failure
0.714 0.286 0.000
F01.9 Vascular dementia, unspecified
0.714 0.286 0.000
L91 Hypertrophic disorders of skin
0.713 0.287 0.000
Chapter XXII Codes for special purposes
0.713 0.287 0.000
C34.2 Middle lobe, bronchus or lung
0.712 0.288 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.712 0.288 0.000
X60-X84 Intentional self-harm
0.712 0.288 0.000
M06.9 Rheumatoid arthritis, unspecified
0.711 0.289 0.000
I88 Nonspecific lymphadenitis
0.711 0.289 0.000
I87 Other disorders of veins
0.711 0.289 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.711 0.289 0.000
J91 Pleural effusion in conditions classified elsewhere
0.710 0.290 0.000
T87 Complications peculiar to reattachment and amputation
0.709 0.291 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.709 0.291 0.000
T91 Sequelae of injuries of neck and trunk
0.709 0.291 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.709 0.291 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.708 0.292 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.708 0.292 0.000
G41 Status epilepticus
0.707 0.293 0.000
D47.2 Monoclonal gammopathy
0.706 0.294 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.705 0.295 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.705 0.295 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.704 0.296 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.704 0.296 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.704 0.296 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.703 0.296 0.000
Y35-Y36 Legal intervention and operations of war
0.703 0.296 0.000
Y10-Y34 Event of undetermined intent
0.703 0.296 0.000
Y00-Y09 Assault
0.703 0.296 0.000
X85-X99 Assault
0.703 0.296 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.703 0.296 0.000
X30-X39 Exposure to forces of nature
0.703 0.296 0.000
X20-X29 Contact with venomous animals and plants
0.703 0.296 0.000
X10-X19 Contact with heat and hot substances
0.703 0.296 0.000
X00-X09 Exposure to smoke, fire and flames
0.703 0.296 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.703 0.296 0.000
W75-W84 Other accidental threats to breathing
0.703 0.296 0.000
W65-W74 Accidental drowning and submersion
0.703 0.296 0.000
W50-W64 Exposure to animate mechanical forces
0.703 0.296 0.000
V98-V99 Other and unspecified transport accidents
0.703 0.296 0.000
V95-V97 Air and space transport accidents
0.703 0.296 0.000
V90-V94 Water transport accidents
0.703 0.296 0.000
V70-V79 Bus occupant injured in transport accident
0.703 0.296 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.703 0.296 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.703 0.296 0.000
V40-V49 Car occupant injured in transport accident
0.703 0.296 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.703 0.296 0.000
V20-V29 Motorcycle rider injured in transport accident
0.703 0.296 0.000
V01-V09 Pedestrian injured in transport accident
0.703 0.296 0.000
M13.9 Arthritis, unspecified
0.703 0.297 0.000
L90 Atrophic disorders of skin
0.702 0.298 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.702 0.298 0.000
I07 Rheumatic tricuspid valve diseases
0.702 0.298 0.000
I84.6 Residual haemorrhoidal skin tags
0.702 0.298 0.000
W00 Fall on same level involving ice and snow
0.701 0.299 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.701 0.299 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.700 0.299 0.000
M85 Other disorders of bone density and structure
0.700 0.300 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.700 0.300 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.699 0.301 0.000
E40-E46 Malnutrition
0.699 0.301 0.000
S92 Fracture of foot, except ankle
0.699 0.301 0.000
R45 Symptoms and signs involving emotional state
0.698 0.302 0.000
D69 Purpura and other haemorrhagic conditions
0.698 0.302 0.000
L03 Cellulitis
0.698 0.302 0.000
E50-E64 Other nutritional deficiencies
0.697 0.302 0.000
J41 Simple and mucopurulent chronic bronchitis
0.697 0.303 0.000
J46 Status asthmaticus
0.697 0.303 0.000
D04.7 Skin of lower limb, including hip
0.697 0.303 0.000
R23 Other skin changes
0.697 0.303 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.696 0.304 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.696 0.304 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.695 0.305 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.695 0.305 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.695 0.305 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.695 0.305 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.694 0.306 0.000
M34 Systemic sclerosis
0.694 0.306 0.000
M33 Dermatopolymyositis
0.694 0.306 0.000
M32 Systemic lupus erythematosus
0.694 0.306 0.000
M30 Polyarteritis nodosa and related conditions
0.694 0.306 0.000
F32 Depressive episode
0.694 0.306 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.693 0.307 0.000
R20 Disturbances of skin sensation
0.693 0.307 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.693 0.307 0.000
I27 Other pulmonary heart diseases
0.693 0.307 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.692 0.308 0.000
M89 Other disorders of bone
0.692 0.308 0.000
S62.3 Fracture of other metacarpal bone
0.692 0.308 0.000
Z54 Convalescence
0.691 0.308 0.000
Z49 Care involving dialysis
0.691 0.308 0.000
Z44 Fitting and adjustment of external prosthetic device
0.691 0.308 0.000
G90-G99 Other disorders of the nervous system
0.691 0.309 0.000
R40 Somnolence, stupor and coma
0.691 0.309 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.691 0.309 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.691 0.309 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.691 0.309 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.691 0.309 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.691 0.309 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.691 0.309 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.690 0.310 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.690 0.310 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.690 0.310 0.000
Z41 Procedures for purposes other than remedying health state
0.690 0.310 0.000
M76 Enthesopathies of lower limb, excluding foot
0.689 0.311 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.689 0.311 0.000
F31 Bipolar affective disorder
0.689 0.311 0.000
M84 Disorders of continuity of bone
0.687 0.312 0.000
G81.1 Spastic hemiplegia
0.687 0.313 0.000
G81.0 Flaccid hemiplegia
0.687 0.313 0.000
Z48.9 Surgical follow-up care, unspecified
0.687 0.313 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.686 0.314 0.000
L05 Pilonidal cyst
0.686 0.314 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.685 0.315 0.000
I05.2 Mitral stenosis with insufficiency
0.685 0.315 0.000
B34 Viral infection of unspecified site
0.684 0.316 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.684 0.316 0.000
C17 Malignant neoplasm of small intestine
0.683 0.317 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.681 0.318 0.000
W19 Unspecified fall
0.681 0.319 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.681 0.319 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.681 0.319 0.000
D46 Myelodysplastic syndromes
0.681 0.319 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.681 0.319 0.000
F70-F79 Mental retardation
0.681 0.319 0.000
F60-F69 Disorders of adult personality and behaviour
0.681 0.319 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.680 0.320 0.000
I86 Varicose veins of other sites
0.680 0.320 0.000
M25.9 Joint disorder, unspecified
0.680 0.320 0.000
M25.3 Other instability of joint
0.680 0.320 0.000
M25.2 Flail joint
0.680 0.320 0.000
M25.1 Fistula of joint
0.680 0.320 0.000
M25.0 Haemarthrosis
0.680 0.320 0.000
M77.4 Metatarsalgia
0.679 0.320 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.679 0.321 0.000
A41 Other septicaemia
0.679 0.321 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.678 0.322 0.000
I08.0 Disorders of both mitral and aortic valves
0.678 0.322 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.678 0.322 0.000
G83 Other paralytic syndromes
0.678 0.322 0.000
S68 Traumatic amputation of wrist and hand
0.678 0.322 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.677 0.323 0.000
I73.9 Peripheral vascular disease, unspecified
0.676 0.324 0.000
I60 Subarachnoid haemorrhage
0.676 0.324 0.000
Y45.0 Opioids and related analgesics
0.676 0.324 0.000
D55-D59 Haemolytic anaemias
0.676 0.324 0.000
M25.77 Osteophyte (Ankle and foot)
0.676 0.324 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.676 0.324 0.000
D47.1 Chronic myeloproliferative disease
0.675 0.325 0.000
L10-L14 Bullous disorders
0.675 0.325 0.000
M11 Other crystal arthropathies
0.675 0.325 0.000
Z52 Donors of organs and tissues
0.675 0.325 0.000
I85 Oesophageal varices
0.674 0.325 0.000
E04.0 Non-toxic diffuse goitre
0.674 0.326 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.674 0.326 0.000
L40-L45 Papulosquamous disorders
0.672 0.328 0.000
Z76 Persons encountering health services in other circumstances
0.672 0.328 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.672 0.328 0.000
C34.9 Bronchus or lung, unspecified
0.672 0.328 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.670 0.330 0.000
S00-S09 Injuries to the head
0.670 0.330 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.670 0.330 0.000
G71 Primary disorders of muscles
0.670 0.330 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.669 0.330 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.669 0.331 0.000
Y83.8 Other surgical procedures
0.668 0.332 0.000
N60-N64 Disorders of breast
0.668 0.332 0.000
M88 Paget's disease of bone [osteitis deformans]
0.667 0.333 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.667 0.333 0.000
I70 Atherosclerosis
0.666 0.333 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.666 0.334 0.000
T98 Sequelae of other and unspecified effects of external causes
0.666 0.334 0.000
T95 Sequelae of burns, corrosions and frostbite
0.666 0.334 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.666 0.334 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.666 0.334 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.666 0.334 0.000
M14 Arthropathies in other diseases classified elsewhere
0.666 0.334 0.000
M12 Other specific arthropathies
0.666 0.334 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.666 0.334 0.000
M08 Juvenile arthritis
0.666 0.334 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.666 0.334 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.666 0.334 0.000
E06 Thyroiditis
0.665 0.334 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.665 0.334 0.000
E00 Congenital iodine-deficiency syndrome
0.665 0.334 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.665 0.334 0.000
I09 Other rheumatic heart diseases
0.665 0.335 0.000
I06 Rheumatic aortic valve diseases
0.665 0.335 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.665 0.335 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.665 0.335 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.665 0.335 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.665 0.335 0.000
I62 Other nontraumatic intracranial haemorrhage
0.664 0.336 0.000
C80 Malignant neoplasm without specification of site
0.664 0.336 0.000
Z48.8 Other specified surgical follow-up care
0.664 0.336 0.000
C20 Malignant neoplasm of rectum
0.664 0.336 0.000
D80-D89 Certain disorders involving the immune mechanism
0.664 0.336 0.000
C51-C58 Malignant neoplasms of female genital organs
0.663 0.336 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.663 0.337 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.663 0.337 0.000
C32 Malignant neoplasm of larynx
0.663 0.337 0.000
C31 Malignant neoplasm of accessory sinuses
0.663 0.337 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.663 0.337 0.000
C37 Malignant neoplasm of thymus
0.663 0.337 0.000
C33 Malignant neoplasm of trachea
0.663 0.337 0.000
B35-B49 Mycoses
0.663 0.337 0.000
M25.53 Pain in joint (Forearm)
0.663 0.337 0.000
M79.9 Soft tissue disorder, unspecified
0.663 0.337 0.000
M79.5 Residual foreign body in soft tissue
0.663 0.337 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.663 0.337 0.000
M79.3 Panniculitis, unspecified
0.663 0.337 0.000
M79.2 Neuralgia and neuritis, unspecified
0.663 0.337 0.000
M79.1 Myalgia
0.663 0.337 0.000
M79.63 Pain in limb (Forearm)
0.662 0.338 0.000
G44.2 Tension-type headache
0.661 0.339 0.000
J47 Bronchiectasis
0.661 0.339 0.000
S40 Superficial injury of shoulder and upper arm
0.660 0.340 0.000
N00-N08 Glomerular diseases
0.659 0.341 0.000
B15-B19 Viral hepatitis
0.659 0.341 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.659 0.341 0.000
M25.59 Pain in joint (Site unspecified)
0.658 0.342 0.000
M25.58 Pain in joint (Other)
0.658 0.342 0.000
M25.52 Pain in joint (Upper arm)
0.658 0.342 0.000
D68 Other coagulation defects
0.658 0.342 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.658 0.342 0.000
E78.2 Mixed hyperlipidaemia
0.657 0.343 0.000
I71 Aortic aneurysm and dissection
0.656 0.344 0.000
I67.1 Cerebral aneurysm, nonruptured
0.656 0.344 0.000
E88 Other metabolic disorders
0.655 0.345 0.000
I05.0 Mitral stenosis
0.655 0.345 0.000
J90 Pleural effusion, not elsewhere classified
0.654 0.346 0.000
I67.2 Cerebral atherosclerosis
0.654 0.346 0.000
G70 Myasthenia gravis and other myoneural disorders
0.654 0.346 0.000
Y83.0 Surgical operation with transplant of whole organ
0.654 0.346 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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