TreeWAS – Variant ID: rs162990

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K83.1 Obstruction of bile duct	0.000	0.838	0.162
K31.8 Other specified diseases of stomach and duodenum	0.093	0.907	0.000
K83 Other diseases of biliary tract	0.000	0.954	0.046
K83.0 Cholangitis	0.000	0.959	0.041
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.000	0.966	0.034
K83.2 Perforation of bile duct	0.000	0.967	0.033
K83.3 Fistula of bile duct	0.000	0.970	0.030
K83.5 Biliary cyst	0.000	0.970	0.029
K83.4 Spasm of sphincter of Oddi	0.000	0.970	0.029
K83.9 Disease of biliary tract, unspecified	0.000	0.973	0.027
K83.8 Other specified diseases of biliary tract	0.000	0.975	0.025
H65.3 Chronic mucoid otitis media	0.021	0.979	0.000
R90 Abnormal findings on diagnostic imaging of central nervous system	0.000	0.984	0.016
H65 Nonsuppurative otitis media	0.015	0.985	0.000
H65.0 Acute serous otitis media	0.013	0.987	0.000
R90.0 Intracranial space-occupying lesion	0.000	0.987	0.013
K31 Other diseases of stomach and duodenum	0.012	0.988	0.000
H65.2 Chronic serous otitis media	0.012	0.988	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.011	0.989	0.000
I07.1 Tricuspid insufficiency	0.011	0.989	0.000
H65.1 Other acute nonsuppurative otitis media	0.011	0.989	0.000
K31.2 Hourglass stricture and stenosis of stomach	0.010	0.990	0.000
H65.4 Other chronic nonsuppurative otitis media	0.010	0.990	0.000
K31.3 Pylorospasm, not elsewhere classified	0.009	0.991	0.000
K31.0 Acute dilatation of stomach	0.009	0.991	0.000
K31.6 Fistula of stomach and duodenum	0.009	0.991	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.009	0.991	0.000
K31.4 Gastric diverticulum	0.008	0.992	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.008	0.992	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.008	0.992	0.000
C03 Malignant neoplasm of gum	0.008	0.992	0.000
C01 Malignant neoplasm of base of tongue	0.008	0.992	0.000
K31.9 Disease of stomach and duodenum, unspecified	0.008	0.992	0.000
C14.0 Pharynx, unspecified	0.008	0.992	0.000
I07 Rheumatic tricuspid valve diseases	0.008	0.992	0.000
C03.1 Lower gum	0.007	0.992	0.000
K31.1 Adult hypertrophic pyloric stenosis	0.007	0.992	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.007	0.993	0.000
C10 Malignant neoplasm of oropharynx	0.007	0.993	0.000
K31.5 Obstruction of duodenum	0.007	0.993	0.000
C02.9 Tongue, unspecified	0.007	0.993	0.000
C09 Malignant neoplasm of tonsil	0.007	0.993	0.000
C04 Malignant neoplasm of floor of mouth	0.007	0.993	0.000
C02.1 Border of tongue	0.007	0.993	0.000
C06.2 Retromolar area	0.007	0.993	0.000
C02.2 Ventral surface of tongue	0.007	0.993	0.000
C11 Malignant neoplasm of nasopharynx	0.006	0.993	0.000
C13 Malignant neoplasm of hypopharynx	0.006	0.994	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.006	0.994	0.000
C00 Malignant neoplasm of lip	0.006	0.994	0.000
C10.9 Oropharynx, unspecified	0.006	0.994	0.000
C05 Malignant neoplasm of palate	0.006	0.994	0.000
C12 Malignant neoplasm of pyriform sinus	0.006	0.994	0.000
C07 Malignant neoplasm of parotid gland	0.006	0.994	0.000
Z92.3 Personal history of irradiation	0.006	0.994	0.000
O63.0 Prolonged first stage (of labour)	0.000	0.994	0.006
C02.8 Overlapping lesion of tongue	0.006	0.994	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.006	0.994	0.000
C02.0 Dorsal surface of tongue	0.006	0.994	0.000
C14.8 Overlapping lesion of lip, oral cavity and pharynx	0.006	0.994	0.000
C14.2 Waldeyer's ring	0.006	0.994	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.006	0.994	0.000
C03.9 Gum, unspecified	0.006	0.994	0.000
C03.0 Upper gum	0.006	0.994	0.000
C02.4 Lingual tonsil	0.006	0.994	0.000
I07.9 Tricuspid valve disease, unspecified	0.006	0.994	0.000
I07.8 Other tricuspid valve diseases	0.006	0.994	0.000
I07.2 Tricuspid stenosis with insufficiency	0.006	0.994	0.000
I07.0 Tricuspid stenosis	0.006	0.994	0.000
I08.8 Other multiple valve diseases	0.006	0.994	0.000
C06.9 Mouth, unspecified	0.005	0.994	0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.005	0.994	0.000
C06.1 Vestibule of mouth	0.005	0.994	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.006	0.994	0.000
C06.0 Cheek mucosa	0.005	0.994	0.000
T39.1 4-Aminophenol derivatives	0.006	0.994	0.000
C10.8 Overlapping lesion of oropharynx	0.005	0.994	0.000
C10.4 Branchial cleft	0.005	0.994	0.000
C10.3 Posterior wall of oropharynx	0.005	0.994	0.000
C10.2 Lateral wall of oropharynx	0.005	0.994	0.000
C10.1 Anterior surface of epiglottis	0.005	0.994	0.000
C10.0 Vallecula	0.005	0.994	0.000
C09.9 Tonsil, unspecified	0.005	0.995	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.005	0.995	0.000
T39.0 Salicylates	0.005	0.995	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
K31.7 Polyp of stomach and duodenum	0.005	0.995	0.000
I08 Multiple valve diseases	0.005	0.995	0.000
C04.9 Floor of mouth, unspecified	0.005	0.995	0.000
E10.1 With ketoacidosis	0.000	0.995	0.005
T46.4 Angiotensin-converting-enzyme inhibitors	0.005	0.995	0.000
C09.8 Overlapping lesion of tonsil	0.005	0.995	0.000
C09.1 Tonsillar pillar (anterior) (posterior)	0.005	0.995	0.000
C09.0 Tonsillar fossa	0.005	0.995	0.000
G35 Multiple sclerosis	0.000	0.995	0.005
T46 Poisoning by agents primarily affecting the cardiovascular system	0.005	0.995	0.000
C04.8 Overlapping lesion of floor of mouth	0.005	0.995	0.000
C04.1 Lateral floor of mouth	0.005	0.995	0.000
C04.0 Anterior floor of mouth	0.005	0.995	0.000
T43.2 Other and unspecified antidepressants	0.005	0.995	0.000
I05-I09 Chronic rheumatic heart diseases	0.005	0.995	0.000
C11.9 Nasopharynx, unspecified	0.005	0.995	0.000
C11.8 Overlapping lesion of nasopharynx	0.005	0.995	0.000
C11.3 Anterior wall of nasopharynx	0.005	0.995	0.000
C11.2 Lateral wall of nasopharynx	0.005	0.995	0.000
C11.1 Posterior wall of nasopharynx	0.005	0.995	0.000
C11.0 Superior wall of nasopharynx	0.005	0.995	0.000
M19.91 Arthrosis, unspecified (Shoulder region)	0.000	0.995	0.005
C00.9 Lip, unspecified	0.005	0.995	0.000
C00.8 Overlapping lesion of lip	0.005	0.995	0.000
C00.6 Commissure of lip	0.005	0.995	0.000
C00.5 Lip, unspecified, inner aspect	0.005	0.995	0.000
C00.4 Lower lip, inner aspect	0.005	0.995	0.000
C00.3 Upper lip, inner aspect	0.005	0.995	0.000
C00.2 External lip, unspecified	0.005	0.995	0.000
C00.1 External lower lip	0.005	0.995	0.000
C00.0 External upper lip	0.005	0.995	0.000
C08.9 Major salivary gland, unspecified	0.005	0.995	0.000
C08.8 Overlapping lesion of major salivary glands	0.005	0.995	0.000
C08.1 Sublingual gland	0.005	0.995	0.000
C08.0 Submandibular gland	0.005	0.995	0.000
C13.9 Hypopharynx, unspecified	0.005	0.995	0.000
C13.8 Overlapping lesion of hypopharynx	0.005	0.995	0.000
C13.2 Posterior wall of hypopharynx	0.005	0.995	0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect	0.005	0.995	0.000
C13.0 Postcricoid region	0.005	0.995	0.000
C05.9 Palate, unspecified	0.005	0.995	0.000
C05.8 Overlapping lesion of palate	0.005	0.995	0.000
C05.2 Uvula	0.005	0.995	0.000
C05.0 Hard palate	0.005	0.995	0.000
T43.6 Psychostimulants with abuse potential	0.005	0.995	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.005	0.995	0.000
H65-H75 Diseases of middle ear and mastoid	0.005	0.995	0.000
C05.1 Soft palate	0.004	0.995	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.004	0.995	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.004	0.995	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.004	0.996	0.000
H70 Mastoiditis and related conditions	0.004	0.996	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.004	0.996	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.004	0.996	0.000
T39.4 Antirheumatics, not elsewhere classified	0.004	0.996	0.000
T39.2 Pyrazolone derivatives	0.004	0.996	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.004	0.996	0.000
I08.0 Disorders of both mitral and aortic valves	0.004	0.996	0.000
T43.9 Psychotropic drug, unspecified	0.004	0.996	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.004	0.996	0.000
I08.9 Multiple valve disease, unspecified	0.004	0.996	0.000
I09 Other rheumatic heart diseases	0.004	0.996	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.004	0.996	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.004	0.996	0.000
T46.7 Peripheral vasodilators	0.004	0.996	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.004	0.996	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.004	0.996	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.004	0.996	0.000
T46.1 Calcium-channel blockers	0.004	0.996	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.004	0.996	0.000
I06 Rheumatic aortic valve diseases	0.004	0.996	0.000
H70.9 Mastoiditis, unspecified	0.004	0.996	0.000
H70.1 Chronic mastoiditis	0.004	0.996	0.000
H68 Eustachian salpingitis and obstruction	0.004	0.996	0.000
N75.0 Cyst of Bartholin's gland	0.000	0.996	0.004
H70.8 Other mastoiditis and related conditions	0.004	0.996	0.000
H66 Suppurative and unspecified otitis media	0.004	0.996	0.000
H73 Other disorders of tympanic membrane	0.004	0.996	0.000
R07.1 Chest pain on breathing	0.004	0.996	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.004	0.996	0.000
H69 Other disorders of Eustachian tube	0.004	0.996	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.003	0.996	0.000
H67 Otitis media in diseases classified elsewhere	0.003	0.996	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.003	0.996	0.000
M79.60 Pain in limb (Multiple sites)	0.000	0.997	0.003
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
F40.2 Specific (isolated) phobias	0.003	0.997	0.000
H70.2 Petrositis	0.003	0.997	0.000
H70.0 Acute mastoiditis	0.003	0.997	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.003	0.997	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.003	0.997	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.003	0.997	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.003	0.997	0.000
I09.9 Rheumatic heart disease, unspecified	0.003	0.997	0.000
F45.8 Other somatoform disorders	0.003	0.997	0.000
H66.9 Otitis media, unspecified	0.003	0.997	0.000
H66.0 Acute suppurative otitis media	0.003	0.997	0.000
T36 Poisoning by systemic antibiotics	0.003	0.997	0.000
H68.1 Obstruction of Eustachian tube	0.003	0.997	0.000
I09.8 Other specified rheumatic heart diseases	0.003	0.997	0.000
I09.2 Chronic rheumatic pericarditis	0.003	0.997	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.003	0.997	0.000
I09.0 Rheumatic myocarditis	0.003	0.997	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.003	0.997	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.003	0.997	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
M19.97 Arthrosis, unspecified (Ankle and foot)	0.000	0.997	0.003
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
I06.9 Rheumatic aortic valve disease, unspecified	0.003	0.997	0.000
I06.8 Other rheumatic aortic valve diseases	0.003	0.997	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.003	0.997	0.000
I06.1 Rheumatic aortic insufficiency	0.003	0.997	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
I06.0 Rheumatic aortic stenosis	0.003	0.997	0.000
H68.0 Eustachian salpingitis	0.003	0.997	0.000
H66.4 Suppurative otitis media, unspecified	0.003	0.997	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.003	0.997	0.000
I95.1 Orthostatic hypotension	0.003	0.997	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.003	0.997	0.000
H73.1 Chronic myringitis	0.003	0.997	0.000
H73.0 Acute myringitis	0.003	0.997	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
T37.5 Antiviral drugs	0.003	0.997	0.000
T37.4 Anthelminthics	0.003	0.997	0.000
T37.3 Other antiprotozoal drugs	0.003	0.997	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
T37.1 Antimycobacterial drugs	0.003	0.997	0.000
T37.0 Sulphonamides	0.003	0.997	0.000
S91.3 Open wound of other parts of foot	0.003	0.997	0.000
H69.8 Other specified disorders of Eustachian tube	0.003	0.997	0.000
H52.2 Astigmatism	0.003	0.997	0.000
H69.0 Patulous Eustachian tube	0.003	0.997	0.000
I05 Rheumatic mitral valve diseases	0.003	0.997	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.003	0.997	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.003	0.997	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.003	0.997	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.003	0.997	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.003	0.997	0.000
H69.9 Eustachian tube disorder, unspecified	0.003	0.997	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.003	0.997	0.000
K35.9 Acute appendicitis, unspecified	0.000	0.997	0.003
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.003	0.997	0.000
S80.8 Other superficial injuries of lower leg	0.003	0.997	0.000
D68.2 Hereditary deficiency of other clotting factors	0.003	0.997	0.000
K62.7 Radiation proctitis	0.003	0.997	0.000
H49.2 Sixth [abducent] nerve palsy	0.003	0.997	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.003	0.997	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.997	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.997	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.003	0.997	0.000
T44.0 Anticholinesterase agents	0.003	0.997	0.000
T41.5 Therapeutic gases	0.003	0.997	0.000
T41.4 Anaesthetic, unspecified	0.003	0.997	0.000
T41.3 Local anaesthetics	0.003	0.997	0.000
T41.2 Other and unspecified general anaesthetics	0.003	0.997	0.000
T41.1 Intravenous anaesthetics	0.003	0.997	0.000
T41.0 Inhaled anaesthetics	0.003	0.997	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.003	0.997	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
T47.7 Emetics	0.003	0.997	0.000
T47.6 Antidiarrhoeal drugs	0.003	0.997	0.000
T47.5 Digestants	0.003	0.997	0.000
T47.4 Other laxatives	0.003	0.997	0.000
T47.3 Saline and osmotic laxatives	0.003	0.997	0.000
T47.2 Stimulant laxatives	0.003	0.997	0.000
T47.0 Histamine H(2)-receptor antagonists	0.003	0.997	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.003	0.997	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.003	0.997	0.000
T48.5 Anti-common-cold drugs	0.003	0.997	0.000
T48.4 Expectorants	0.003	0.997	0.000
T48.3 Antitussives	0.003	0.997	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.003	0.997	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.003	0.997	0.000
T48.0 Oxytocic drugs	0.003	0.997	0.000
T49.9 Topical agent, unspecified	0.003	0.997	0.000
T49.8 Other topical agents	0.003	0.997	0.000
T49.7 Dental drugs, topically applied	0.003	0.997	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.003	0.997	0.000
T49.5 Ophthalmological drugs and preparations	0.003	0.997	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.997	0.000
T49.3 Emollients, demulcents and protectants	0.003	0.997	0.000
T49.2 Local astringents and local detergents	0.003	0.997	0.000
T49.1 Antipruritics	0.003	0.997	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.003	0.997	0.000
H74 Other disorders of middle ear and mastoid	0.003	0.997	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.003	0.997	0.000
F45 Somatoform disorders	0.003	0.997	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.003	0.997	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.003	0.997	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.000	0.997	0.003
T36.9 Systemic antibiotic, unspecified	0.002	0.997	0.000
T36.8 Other systemic antibiotics	0.002	0.997	0.000
T36.7 Antifungal antibiotics, systemically used	0.002	0.997	0.000
T36.6 Rifamycins	0.002	0.997	0.000
T36.5 Aminoglycosides	0.002	0.997	0.000
T36.4 Tetracyclines	0.002	0.997	0.000
T36.3 Macrolides	0.002	0.997	0.000
T36.2 Chloramphenicol group	0.002	0.997	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.002	0.997	0.000
F40 Phobic anxiety disorders	0.003	0.997	0.000
F44.5 Dissociative convulsions	0.003	0.997	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.003	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.002	0.997	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.997	0.000
T38.7 Androgens and anabolic congeners	0.002	0.997	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.002	0.997	0.000
T38.5 Other oestrogens and progestogens	0.002	0.997	0.000
T38.4 Oral contraceptives	0.002	0.997	0.000
T38.2 Antithyroid drugs	0.002	0.997	0.000
T38.0 Glucocorticoids and synthetic analogues	0.002	0.997	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
T38.1 Thyroid hormones and substitutes	0.002	0.997	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.997	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.997	0.003
S91 Open wound of ankle and foot	0.002	0.997	0.000
F45.3 Somatoform autonomic dysfunction	0.002	0.998	0.000
T50.8 Diagnostic agents	0.002	0.998	0.000
T50.7 Analeptics and opioid receptor antagonists	0.002	0.998	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
T50.5 Appetite depressants	0.002	0.998	0.000
T50.4 Drugs affecting uric acid metabolism	0.002	0.998	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
T50.1 Loop [high-ceiling] diuretics	0.002	0.998	0.000
T50.0 Mineralocorticoids and their antagonists	0.002	0.998	0.000
H66.3 Other chronic suppurative otitis media	0.002	0.998	0.000
H73.8 Other specified disorders of tympanic membrane	0.002	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
F44 Dissociative [conversion] disorders	0.002	0.998	0.000
S93.1 Dislocation of toe(s)	0.002	0.998	0.000
T36.0 Penicillins	0.002	0.998	0.000
I05.8 Other mitral valve diseases	0.002	0.998	0.000
S12.2 Fracture of other specified cervical vertebra	0.002	0.998	0.000
F40.8 Other phobic anxiety disorders	0.002	0.998	0.000
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
T00.3 Superficial injuries involving multiple regions of lower limb(s)	0.002	0.998	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.998	0.000
T45.8 Other primarily systemic and haematological agents	0.002	0.998	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
T45.6 Fibrinolysis-affecting drugs	0.002	0.998	0.000
T45.4 Iron and its compounds	0.002	0.998	0.000
T45.3 Enzymes, not elsewhere classified	0.002	0.998	0.000
T45.2 Vitamins, not elsewhere classified	0.002	0.998	0.000
F05.9 Delirium, unspecified	0.002	0.998	0.000
H74.1 Adhesive middle ear disease	0.002	0.998	0.000
M25.77 Osteophyte (Ankle and foot)	0.000	0.998	0.002
I05.0 Mitral stenosis	0.002	0.998	0.000
K02.8 Other dental caries	0.002	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
S91.0 Open wound of ankle	0.002	0.998	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.002	0.998	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.000	0.998	0.002
F44.9 Dissociative [conversion] disorder, unspecified	0.002	0.998	0.000
F45.9 Somatoform disorder, unspecified	0.002	0.998	0.000
F45.4 Persistent somatoform pain disorder	0.002	0.998	0.000
F45.2 Hypochondriacal disorder	0.002	0.998	0.000
F45.1 Undifferentiated somatoform disorder	0.002	0.998	0.000
F45.0 Somatisation disorder	0.002	0.998	0.000
H52.0 Hypermetropia	0.002	0.998	0.000
S91.2 Open wound of toe(s) with damage to nail	0.002	0.998	0.000
R92 Abnormal findings on diagnostic imaging of breast	0.000	0.998	0.002
U51.1 Previously admitted to a psychiatric hospital of the provider	0.002	0.998	0.000
H52 Disorders of refraction and accommodation	0.002	0.998	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.998	0.002
S52.20 Fracture of shaft of ulna (closed)	0.002	0.998	0.000
O21.0 Mild hyperemesis gravidarum	0.002	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.002	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.998	0.000
F40.9 Phobic anxiety disorder, unspecified	0.002	0.998	0.000
F40.1 Social phobias	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
F44.4 Dissociative motor disorders	0.002	0.998	0.000
I05.1 Rheumatic mitral insufficiency	0.002	0.998	0.000
N48.6 Balanitis xerotica obliterans	0.000	0.998	0.002
M13.09 Polyarthritis, unspecified (Site unspecified)	0.002	0.998	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.002	0.998	0.000
F33.9 Recurrent depressive disorder, unspecified	0.000	0.998	0.002
I05.2 Mitral stenosis with insufficiency	0.002	0.998	0.000
H49 Paralytic strabismus	0.002	0.998	0.000
S12 Fracture of neck	0.002	0.998	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.000	0.998	0.002
D04.6 Skin of upper limb, including shoulder	0.000	0.998	0.002
Q85.0 Neurofibromatosis (nonmalignant)	0.002	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.002	0.998	0.000
S91.7 Multiple open wounds of ankle and foot	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
S12.9 Fracture of neck, part unspecified	0.002	0.998	0.000
C21.0 Anus, unspecified	0.002	0.998	0.000
K66.8 Other specified disorders of peritoneum	0.000	0.998	0.002
S90.0 Contusion of ankle	0.002	0.998	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.002	0.998	0.000
F44.8 Other dissociative [conversion] disorders	0.002	0.998	0.000
F44.7 Mixed dissociative [conversion] disorders	0.002	0.998	0.000
F44.6 Dissociative anaesthesia and sensory loss	0.002	0.998	0.000
F44.3 Trance and possession disorders	0.002	0.998	0.000
F44.2 Dissociative stupor	0.002	0.998	0.000
F44.1 Dissociative fugue	0.002	0.998	0.000
F44.0 Dissociative amnesia	0.002	0.998	0.000
H52.3 Anisometropia and aniseikonia	0.002	0.998	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.002	0.998	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.998	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.002	0.998	0.000
S90-S99 Injuries to the ankle and foot	0.002	0.998	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.002	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.002	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.002	0.998	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.002	0.998	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.002	0.998	0.000
H49.1 Fourth [trochlear] nerve palsy	0.002	0.998	0.000
I05.9 Mitral valve disease, unspecified	0.002	0.998	0.000
F48 Other neurotic disorders	0.002	0.998	0.000
H74.0 Tympanosclerosis	0.002	0.998	0.000
J02.9 Acute pharyngitis, unspecified	0.002	0.998	0.000
H72 Perforation of tympanic membrane	0.002	0.998	0.000
H52.7 Disorder of refraction, unspecified	0.002	0.998	0.000
S12.0 Fracture of first cervical vertebra	0.002	0.998	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.002	0.998	0.000
T00 Superficial injuries involving multiple body regions	0.002	0.998	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
F40.0 Agoraphobia	0.002	0.998	0.000
H52.6 Other disorders of refraction	0.002	0.998	0.000
H52.5 Disorders of accommodation	0.002	0.998	0.000
H52.4 Presbyopia	0.002	0.998	0.000
G36 Other acute disseminated demyelination	0.000	0.998	0.002
F00.9 Dementia in Alzheimer's disease, unspecified	0.002	0.998	0.000
F48.0 Neurasthenia	0.002	0.998	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
S22.10 Multiple fractures of thoracic spine (closed)	0.002	0.998	0.000
G91.1 Obstructive hydrocephalus	0.002	0.998	0.000
H72.2 Other marginal perforations of tympanic membrane	0.002	0.998	0.000
T45.5 Anticoagulants	0.001	0.998	0.001
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
G70.0 Myasthenia gravis	0.002	0.998	0.000
H49.8 Other paralytic strabismus	0.002	0.998	0.000
H49.4 Progressive external ophthalmoplegia	0.002	0.998	0.000
H49.3 Total (external) ophthalmoplegia	0.002	0.998	0.000
S12.8 Fracture of other parts of neck	0.002	0.998	0.000
S91.1 Open wound of toe(s) without damage to nail	0.002	0.998	0.000
H71 Cholesteatoma of middle ear	0.002	0.998	0.000
S12.00 Fracture of first cervical vertebra (closed)	0.002	0.998	0.000
S12.1 Fracture of second cervical vertebra	0.002	0.998	0.000
S93.4 Sprain and strain of ankle	0.002	0.998	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.002	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.002	0.998	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.002	0.998	0.000
S12.91 Fracture of neck, part unspecified (open)	0.002	0.998	0.000
F48.9 Neurotic disorder, unspecified	0.002	0.998	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.001	0.998	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
T00.6 Superficial injuries involving multiple regions of upper limb(s) with lower limb(s)	0.002	0.998	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.000	0.998	0.002
G37 Other demyelinating diseases of central nervous system	0.000	0.998	0.002
F05.1 Delirium superimposed on dementia	0.002	0.998	0.000
Q21.1 Atrial septal defect	0.002	0.998	0.000
T00.2 Superficial injuries involving multiple regions of upper limb(s)	0.002	0.998	0.000
F00 Dementia in Alzheimer's disease	0.002	0.998	0.000
G30.0 Alzheimer's disease with early onset	0.002	0.998	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.001	0.998	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.001	0.998	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.001	0.998	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.001	0.998	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.001	0.998	0.000
T40.8 Lysergide [LSD]	0.001	0.998	0.000
T40.7 Cannabis (derivatives)	0.001	0.998	0.000
T40.5 Cocaine	0.001	0.998	0.000
T40.3 Methadone	0.001	0.998	0.000
T40.1 Heroin	0.001	0.998	0.000
T40.0 Opium	0.001	0.998	0.000
S98 Traumatic amputation of ankle and foot	0.002	0.998	0.000
S97 Crushing injury of ankle and foot	0.002	0.998	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.998	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.002	0.998	0.000
F05.8 Other delirium	0.002	0.998	0.000
H49.9 Paralytic strabismus, unspecified	0.002	0.998	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.002	0.998	0.000
L29.8 Other pruritus	0.002	0.998	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.000	0.998	0.002
S12.7 Multiple fractures of cervical spine	0.002	0.998	0.000
Q21 Congenital malformations of cardiac septa	0.002	0.998	0.000
F48.8 Other specified neurotic disorders	0.001	0.998	0.000
F48.1 Depersonalisation-derealisation syndrome	0.001	0.998	0.000
S12.01 Fracture of first cervical vertebra (open)	0.001	0.998	0.000
D04.4 Skin of scalp and neck	0.000	0.998	0.002
M13.00 Polyarthritis, unspecified (Multiple sites)	0.002	0.998	0.000
G30.9 Alzheimer's disease, unspecified	0.002	0.998	0.000
H49.0 Third [oculomotor] nerve palsy	0.002	0.998	0.000
H93.8 Other specified disorders of ear	0.002	0.998	0.000
T00.9 Multiple superficial injuries, unspecified	0.001	0.998	0.000
T00.8 Superficial injuries involving other combinations of body regions	0.001	0.998	0.000
T00.1 Superficial injuries involving thorax with abdomen, lower back and pelvis	0.001	0.998	0.000
T00.0 Superficial injuries involving head with neck	0.001	0.998	0.000
G36.9 Acute disseminated demyelination, unspecified	0.000	0.998	0.001
G36.8 Other specified acute disseminated demyelination	0.000	0.998	0.001
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.998	0.001
G36.0 Neuromyelitis optica [Devic]	0.000	0.998	0.001
H74.4 Polyp of middle ear	0.001	0.998	0.000
I24.8 Other forms of acute ischaemic heart disease	0.002	0.998	0.000
Q21.3 Tetralogy of Fallot	0.002	0.998	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.002	0.998	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.998	0.001
Q28.2 Arteriovenous malformation of cerebral vessels	0.002	0.998	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations