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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1635501
log Bayes Factor = 0.55702
Chromosome 1   position 242,040,775  (GRCh37) Explore rs1635501 on Ensembl!
Variant rs1635501 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
H04.2 Epiphora
0.000 0.444 0.556
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.455 0.545 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.446 0.554 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.444 0.556 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.442 0.558 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.433 0.567 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.427 0.573 0.000
H04 Disorders of lachrymal system
0.000 0.575 0.425
Y45.0 Opioids and related analgesics
0.424 0.576 0.000
Y54.8 Agents affecting uric acid metabolism
0.410 0.590 0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified
0.397 0.603 0.000
Y52 Agents primarily affecting the cardiovascular system
0.381 0.619 0.000
Y48 Anaesthetics and therapeutic gases
0.381 0.619 0.000
H04.1 Other disorders of lachrymal gland
0.000 0.622 0.378
Y41 Other systemic anti-infectives and antiparasitics
0.369 0.631 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.360 0.640 0.000
Y45.2 Propionic acid derivatives
0.351 0.649 0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.351 0.649 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.000 0.650 0.350
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system
0.349 0.651 0.000
H04.4 Chronic inflammation of lachrymal passages
0.000 0.651 0.349
Y50 Central nervous system stimulants, not elsewhere classified
0.347 0.653 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.344 0.656 0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]
0.343 0.657 0.000
H04.8 Other disorders of lachrymal system
0.000 0.660 0.340
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified
0.336 0.663 0.000
Y45.4 Antirheumatics
0.336 0.664 0.000
Y42.5 Other oestrogens and progestogens
0.323 0.677 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.322 0.678 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.000 0.680 0.320
Y54.3 Benzothiadiazine derivatives
0.319 0.681 0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified
0.318 0.682 0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.318 0.682 0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified
0.318 0.682 0.000
Y51.1 Other parasympathomimetics [cholinergics]
0.318 0.682 0.000
Y51.0 Anticholinesterase agents
0.318 0.682 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.316 0.684 0.000
Y48.3 Local anaesthetics
0.314 0.686 0.000
Y54.7 Agents affecting calcification
0.312 0.688 0.000
Y48.4 Anaesthetic, unspecified
0.312 0.688 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.309 0.690 0.000
Y54.5 Other diuretics
0.309 0.691 0.000
Y41.5 Antiviral drugs
0.307 0.693 0.000
Y54.9 Mineral salts, not elsewhere classified
0.306 0.694 0.000
Y54.6 Electrolytic, caloric and water-balance agents
0.306 0.694 0.000
Y54.2 Carbonic-anhydrase inhibitors
0.306 0.694 0.000
Y54.0 Mineralocorticoids
0.306 0.694 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.306 0.694 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.306 0.694 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.305 0.695 0.000
Y52.1 Calcium-channel blockers
0.300 0.700 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.300 0.700 0.000
Y54.4 Loop [high-ceiling] diuretics
0.294 0.706 0.000
Y52.7 Peripheral vasodilators
0.293 0.707 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.292 0.708 0.000
Y59 Other and unspecified vaccines and biological substances
0.288 0.712 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.287 0.713 0.000
Y58 Bacterial vaccines
0.285 0.714 0.000
H04.0 Dacryoadenitis
0.000 0.719 0.281
Y50.2 Methylxanthines, not elsewhere classified
0.280 0.720 0.000
Y42.1 Thyroid hormones and substitutes
0.279 0.721 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.278 0.721 0.000
Y41.0 Sulphonamides
0.278 0.722 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.274 0.726 0.000
Y48.5 Therapeutic gases
0.273 0.727 0.000
Y48.1 Parenteral anaesthetics
0.273 0.727 0.000
Y48.0 Inhaled anaesthetics
0.273 0.727 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.272 0.727 0.000
Y48.2 Other and unspecified general anaesthetics
0.271 0.729 0.000
Y42.4 Oral contraceptives
0.268 0.732 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.267 0.733 0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified
0.264 0.735 0.000
Y41.4 Anthelminthics
0.264 0.735 0.000
Y41.3 Other antiprotozoal drugs
0.264 0.735 0.000
Y41.1 Antimycobacterial drugs
0.260 0.740 0.000
H04.6 Other changes in lachrymal passages
0.000 0.742 0.258
Y42.0 Glucocorticoids and synthetic analogs
0.253 0.747 0.000
Y46.6 Other and unspecified antiepileptics
0.253 0.747 0.000
Y42.2 Antithyroid drugs
0.252 0.748 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.250 0.750 0.000
Y50.9 Central nervous system stimulant, unspecified
0.249 0.751 0.000
Y50.8 Other central nervous system stimulants
0.249 0.751 0.000
Y50.1 Opioid receptor antagonists
0.249 0.751 0.000
Y50.0 Analeptics
0.249 0.751 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.247 0.753 0.000
Y45.5 4-Aminophenol derivatives
0.245 0.755 0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa
0.244 0.755 0.000
Y46.7 Anti-Parkinsonism drugs
0.242 0.758 0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.241 0.759 0.000
Y55.4 Expectorants
0.239 0.760 0.000
Y42.9 Other and unspecified hormone antagonists
0.235 0.764 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.235 0.765 0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system
0.231 0.769 0.000
Y55.5 Anticommon cold drugs
0.231 0.769 0.000
Y55.3 Antitussives
0.231 0.769 0.000
Y55.2 Other and unspecified agents primarily acting on muscles
0.231 0.769 0.000
Y55.0 Oxytocic drugs
0.231 0.769 0.000
Y57 Other and unspecified drugs and medicaments
0.230 0.770 0.000
Y56.3 Emollients, demulcents and protectants
0.229 0.771 0.000
H04.9 Disorder of lachrymal system, unspecified
0.000 0.771 0.229
Y46.8 Antispasticity drugs
0.227 0.773 0.000
Y46.3 Deoxybarbiturates
0.227 0.773 0.000
Y46.1 Oxazolidinediones
0.227 0.773 0.000
Y46.0 Succinimides
0.227 0.773 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.226 0.774 0.000
Y53.1 Other antacids and anti-gastric-secretion drugs
0.220 0.780 0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified
0.219 0.781 0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs
0.219 0.781 0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified
0.219 0.781 0.000
Y47.4 Bromine compounds
0.219 0.781 0.000
Y47.3 Paraldehyde
0.219 0.781 0.000
Y47.2 Chloral derivatives
0.219 0.781 0.000
Y47.0 Barbiturates, not elsewhere classified
0.219 0.781 0.000
Y55.6 Antiasthmatics, not elsewhere classified
0.218 0.782 0.000
Y56.9 Topical agent, unspecified
0.215 0.785 0.000
Y56.8 Other topical agents
0.215 0.785 0.000
Y56.7 Dental drugs, topically applied
0.215 0.785 0.000
Y56.6 Otorhinolaryngological drugs and preparations
0.215 0.785 0.000
Y56.5 Ophthalmological drugs and preparations
0.215 0.785 0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.215 0.785 0.000
Y56.2 Local astringents and local detergents
0.215 0.785 0.000
Y56.1 Antipruritics
0.215 0.785 0.000
Y46.4 Iminostilbenes
0.213 0.787 0.000
Y46.5 Valproic acid
0.210 0.790 0.000
Y44 Agents primarily affecting blood constituents
0.207 0.793 0.000
Y59.9 Vaccine or biological substance, unspecified
0.207 0.793 0.000
Y59.8 Other specified vaccines and biological substances
0.207 0.793 0.000
Y59.2 Protozoal vaccines
0.207 0.793 0.000
Y59.1 Rickettsial vaccines
0.207 0.793 0.000
Y47.1 Benzodiazepines
0.207 0.793 0.000
Y46.2 Hydantoin derivatives
0.205 0.794 0.000
Y58.9 Other and unspecified bacterial vaccines
0.205 0.795 0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component
0.205 0.795 0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component
0.205 0.795 0.000
Y58.5 Diphtheria vaccine
0.205 0.795 0.000
Y58.4 Tetanus vaccine
0.205 0.795 0.000
Y58.3 Plague vaccine
0.205 0.795 0.000
Y58.2 Cholera vaccine
0.205 0.795 0.000
Y58.1 Typhoid and paratyphoid vaccine
0.205 0.795 0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.200 0.800 0.000
Y53.7 Emetics
0.200 0.800 0.000
Y53.6 Antidiarrhoeal drugs
0.200 0.800 0.000
Y53.5 Digestants
0.200 0.800 0.000
Y53.2 Stimulant laxatives
0.200 0.800 0.000
Y53.0 Histamine H2-receptor antagonists
0.200 0.800 0.000
Y59.3 Immunoglobulin
0.197 0.803 0.000
Y53.3 Saline and osmotic laxatives
0.194 0.806 0.000
Y59.0 Viral vaccines
0.190 0.809 0.000
Y43 Primarily systemic agents
0.186 0.814 0.000
Y45.1 Salicylates
0.185 0.815 0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.179 0.821 0.000
Y49.9 Psychotropic drug, unspecified
0.177 0.823 0.000
Y49.7 Psychostimulants with abuse potential
0.177 0.823 0.000
Y49.6 Psychodysleptics [hallucinogens]
0.177 0.823 0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics
0.177 0.823 0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics
0.177 0.823 0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants
0.177 0.823 0.000
Y58.0 BCG vaccine
0.174 0.826 0.000
Y53.4 Other laxatives
0.172 0.827 0.000
Y49.8 Other psychotropic drugs, not elsewhere classified
0.172 0.828 0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system
0.170 0.830 0.000
Y49.5 Other antipsychotics and neuroleptics
0.166 0.834 0.000
Y57.7 Vitamins, not elsewhere classified
0.165 0.835 0.000
Y57.4 Pharmaceutical excipients
0.165 0.835 0.000
Y57.3 Alcohol deterrents
0.165 0.835 0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified
0.165 0.835 0.000
Y57.1 Lipotropic drugs
0.165 0.835 0.000
Y57.0 Appetite depressants [anorectics]
0.165 0.835 0.000
Y44.5 Thrombolytic drugs
0.163 0.837 0.000
Y49.2 Other and unspecified antidepressants
0.161 0.839 0.000
Y49.0 Tricyclic and tetracyclic antidepressants
0.156 0.844 0.000
Y57.9 Drug or medicament, unspecified
0.155 0.845 0.000
Y57.8 Other drugs and medicaments
0.154 0.846 0.000
Y57.6 Other diagnostic agents
0.153 0.846 0.000
Y43.0 Antiallergic and antiemetic drugs
0.153 0.847 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.151 0.849 0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations
0.150 0.850 0.000
Y44.9 Other and unspecified agents affecting blood constituents
0.148 0.851 0.000
Y44.7 Plasma substitutes
0.148 0.851 0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations
0.148 0.851 0.000
Y40 Systemic antibiotics
0.148 0.852 0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants
0.146 0.854 0.000
Y44.6 Natural blood and blood products
0.143 0.857 0.000
Y45.8 Other analgesics and antipyretics
0.141 0.858 0.001
Y43.4 Immunosuppressive agents
0.142 0.858 0.000
Y57.5 X-ray contrast media
0.136 0.864 0.000
Y43.9 Primarily systemic agent, unspecified
0.134 0.866 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.134 0.866 0.000
Y43.6 Enzymes, not elsewhere classified
0.134 0.866 0.000
Y43.5 Acidifying and alkalising agents
0.134 0.866 0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]
0.128 0.871 0.000
Y40.5 Aminoglycosides
0.122 0.878 0.000
Y40.7 Antifungal antibiotics, systemically used
0.120 0.880 0.000
Y42.7 Androgens and anabolic congeners
0.118 0.882 0.000
Y43.2 Antineoplastic natural products
0.118 0.882 0.000
Y43.1 Antineoplastic antimetabolites
0.109 0.891 0.000
Y40.2 Chloramphenicol group
0.106 0.894 0.000
Y40.3 Macrolides
0.104 0.896 0.000
Y40.6 Rifamycins
0.100 0.899 0.000
Y40.0 Penicillins
0.092 0.908 0.000
Y40.4 Tetracyclines
0.091 0.909 0.000
Y40.8 Other systemic antibiotics
0.087 0.913 0.000
H40.2 Primary angle-closure glaucoma
0.085 0.915 0.000
Y40.9 Systemic antibiotic, unspecified
0.068 0.931 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.066 0.934 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.000 0.937 0.063
Y44.2 Anticoagulants
0.058 0.942 0.000
H05 Disorders of orbit
0.000 0.946 0.054
H03 Disorders of eyelid in diseases classified elsewhere
0.000 0.951 0.049
H05.8 Other disorders of orbit
0.000 0.952 0.048
H05.1 Chronic inflammatory disorders of orbit
0.000 0.956 0.044
H00 Hordeolum and chalazion
0.000 0.958 0.042
H05.2 Exophthalmic conditions
0.000 0.959 0.041
H05.0 Acute inflammation of orbit
0.000 0.959 0.041
H05.5 Retained (old) foreign body following penetrating wound of orbit
0.000 0.961 0.039
H05.3 Deformity of orbit
0.000 0.961 0.039
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere
0.000 0.961 0.039
H05.4 Enophthalmos
0.000 0.962 0.038
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.000 0.964 0.036
H03.8 Involvement of eyelid in other diseases classified elsewhere
0.000 0.964 0.035
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere
0.000 0.964 0.035
H01 Other inflammation of eyelid
0.000 0.965 0.035
H00.0 Hordeolum and other deep inflammation of eyelid
0.000 0.967 0.032
H05.9 Disorder of orbit, unspecified
0.000 0.971 0.028
H06.3 Other disorders of orbit in diseases classified elsewhere
0.000 0.974 0.026
H06.1 Parasitic infestation of orbit in diseases classified elsewhere
0.000 0.974 0.026
H06.0 Disorders of lachrymal system in diseases classified elsewhere
0.000 0.974 0.026
H01.1 Non-infectious dermatoses of eyelid
0.000 0.974 0.026
H01.9 Inflammation of eyelid, unspecified
0.000 0.975 0.025
H00.1 Chalazion
0.000 0.976 0.024
C81.9 Hodgkin's disease, unspecified
0.024 0.976 0.000
H01.0 Blepharitis
0.000 0.977 0.023
H01.8 Other specified inflammation of eyelid
0.000 0.981 0.019
C81 Hodgkin's disease
0.018 0.982 0.000
H06.2 Dysthyroid exophthalmos
0.000 0.983 0.017
C81.1 Nodular sclerosis
0.015 0.985 0.000
C81.0 Lymphocytic predominance
0.014 0.985 0.000
C81.7 Other Hodgkin's disease
0.014 0.986 0.000
C81.2 Mixed cellularity
0.014 0.986 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.013 0.987 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.013 0.987 0.000
C81.3 Lymphocytic depletion
0.013 0.987 0.000
J34.3 Hypertrophy of nasal turbinates
0.011 0.989 0.000
H40 Glaucoma
0.010 0.990 0.000
N80.1 Endometriosis of ovary
0.009 0.991 0.000
H40.4 Glaucoma secondary to eye inflammation
0.007 0.992 0.000
H40.3 Glaucoma secondary to eye trauma
0.007 0.993 0.000
H40.6 Glaucoma secondary to drugs
0.007 0.993 0.000
C71.9 Brain, unspecified
0.007 0.993 0.000
C71.1 Frontal lobe
0.007 0.993 0.000
N80.8 Other endometriosis
0.007 0.993 0.000
R90.0 Intracranial space-occupying lesion
0.007 0.993 0.000
C71 Malignant neoplasm of brain
0.007 0.993 0.000
C45.0 Mesothelioma of pleura
0.007 0.993 0.000
H40.8 Other glaucoma
0.006 0.994 0.000
N30.3 Trigonitis
0.000 0.994 0.006
Y43.3 Other antineoplastic drugs
0.006 0.994 0.000
H40.5 Glaucoma secondary to other eye disorders
0.006 0.994 0.000
S72.20 Subtrochanteric fracture (closed)
0.006 0.994 0.000
H40.9 Glaucoma, unspecified
0.006 0.994 0.000
C71.2 Temporal lobe
0.005 0.994 0.000
C71.6 Cerebellum
0.005 0.995 0.000
C71.5 Cerebral ventricle
0.005 0.995 0.000
C71.4 Occipital lobe
0.005 0.995 0.000
C45 Mesothelioma
0.005 0.995 0.000
C45.7 Mesothelioma of other sites
0.005 0.995 0.000
N80 Endometriosis
0.005 0.995 0.000
C71.0 Cerebrum, except lobes and ventricles
0.005 0.995 0.000
C71.7 Brain stem
0.005 0.995 0.000
G35 Multiple sclerosis
0.005 0.995 0.000
M10.9 Gout, unspecified
0.005 0.995 0.000
N80.2 Endometriosis of Fallopian tube
0.005 0.995 0.000
R25.1 Tremor, unspecified
0.005 0.995 0.000
C45.9 Mesothelioma, unspecified
0.004 0.996 0.000
C71.3 Parietal lobe
0.004 0.996 0.000
N80.0 Endometriosis of uterus
0.004 0.996 0.000
H40.1 Primary open-angle glaucoma
0.004 0.996 0.000
C45.2 Mesothelioma of pericardium
0.004 0.996 0.000
C45.1 Mesothelioma of peritoneum
0.004 0.996 0.000
H40-H42 Glaucoma
0.004 0.996 0.000
M10.92 Gout, unspecified (Upper arm)
0.004 0.996 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.004 0.996 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.004 0.996 0.000
M10.93 Gout, unspecified (Forearm)
0.004 0.996 0.000
M10.98 Gout, unspecified (Other)
0.003 0.996 0.000
M10.95 Gout, unspecified (Pelvic region and thigh)
0.003 0.996 0.000
M10.91 Gout, unspecified (Shoulder region)
0.003 0.996 0.000
N80.6 Endometriosis in cutaneous scar
0.003 0.996 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.004 0.996 0.000
M10.90 Gout, unspecified (Multiple sites)
0.003 0.996 0.000
M10.94 Gout, unspecified (Hand)
0.003 0.996 0.000
C71.8 Overlapping lesion of brain
0.003 0.996 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.997 0.003
C73 Malignant neoplasm of thyroid gland
0.003 0.997 0.000
N80.5 Endometriosis of intestine
0.003 0.997 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.003 0.997 0.000
I82.2 Embolism and thrombosis of vena cava
0.003 0.997 0.000
H42 Glaucoma in diseases classified elsewhere
0.003 0.997 0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system
0.003 0.997 0.000
F33.9 Recurrent depressive disorder, unspecified
0.000 0.997 0.003
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.003 0.997 0.000
I67.1 Cerebral aneurysm, nonruptured
0.000 0.997 0.003
M89.07 Algoneurodystrophy (Ankle and foot)
0.003 0.997 0.000
M31.3 Wegener's granulomatosis
0.003 0.997 0.000
G37 Other demyelinating diseases of central nervous system
0.003 0.997 0.000
S72.2 Subtrochanteric fracture
0.003 0.997 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.003 0.997 0.000
H40.0 Glaucoma suspect
0.003 0.997 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.003 0.997 0.000
M35.3 Polymyalgia rheumatica
0.003 0.997 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.003 0.997 0.000
M89.09 Algoneurodystrophy (Site unspecified)
0.003 0.997 0.000
N80.3 Endometriosis of pelvic peritoneum
0.003 0.997 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.003 0.997 0.000
M10.96 Gout, unspecified (Lower leg)
0.003 0.997 0.000
S36.00 Injury of spleen (without open wound into cavity)
0.000 0.997 0.003
H42.8 Glaucoma in other diseases classified elsewhere
0.002 0.997 0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases
0.002 0.997 0.000
M89.0 Algoneurodystrophy
0.003 0.997 0.000
C70 Malignant neoplasm of meninges
0.002 0.997 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.002 0.998 0.000
Q44.6 Cystic disease of liver
0.000 0.998 0.002
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.002 0.998 0.000
C48.2 Peritoneum, unspecified
0.002 0.998 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.002 0.998 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.002 0.998 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.002 0.998 0.000
G37.5 Concentric sclerosis [Balo]
0.002 0.998 0.000
G37.4 Subacute necrotising myelitis
0.002 0.998 0.000
G37.2 Central pontine myelinolysis
0.002 0.998 0.000
G37.1 Central demyelination of corpus callosum
0.002 0.998 0.000
G37.0 Diffuse sclerosis
0.002 0.998 0.000
I97.1 Other functional disturbances following cardiac surgery
0.002 0.998 0.000
M89.06 Algoneurodystrophy (Lower leg)
0.002 0.998 0.000
S72.21 Subtrochanteric fracture (open)
0.002 0.998 0.000
H90.3 Sensorineural hearing loss, bilateral
0.002 0.998 0.000
M89.00 Algoneurodystrophy (Multiple sites)
0.002 0.998 0.000
S81.9 Open wound of lower leg, part unspecified
0.002 0.998 0.000
S81.0 Open wound of knee
0.002 0.998 0.000
C69 Malignant neoplasm of eye and adnexa
0.002 0.998 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.002 0.998 0.000
M10 Gout
0.002 0.998 0.000
Z57.5 Occupational exposure to toxic agents in other industries
0.002 0.998 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.002 0.998 0.000
L89.2 Stage III decubitus ulcer
0.000 0.998 0.002
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.000 0.998 0.002
C48.0 Retroperitoneum
0.002 0.998 0.000
M47.16 Other spondylosis with myelopathy (Lumbar region)
0.000 0.998 0.002
L89.1 Stage II decubitus ulcer
0.000 0.998 0.002
H90 Conductive and sensorineural hearing loss
0.002 0.998 0.000
E80.4 Gilbert's syndrome
0.000 0.998 0.002
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.002 0.998 0.000
C70.0 Cerebral meninges
0.002 0.998 0.000
C75.5 Aortic body and other paraganglia
0.002 0.998 0.000
M89.08 Algoneurodystrophy (Other)
0.002 0.998 0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)
0.002 0.998 0.000
M89.02 Algoneurodystrophy (Upper arm)
0.002 0.998 0.000
M89.01 Algoneurodystrophy (Shoulder region)
0.002 0.998 0.000
C69.6 Orbit
0.002 0.998 0.000
C75.9 Endocrine gland, unspecified
0.002 0.998 0.000
I49.3 Ventricular premature depolarisation
0.000 0.998 0.002
I97.2 Postmastectomy lymphoedema syndrome
0.002 0.998 0.000
C70.9 Meninges, unspecified
0.002 0.998 0.000
C70.1 Spinal meninges
0.002 0.998 0.000
G36 Other acute disseminated demyelination
0.002 0.998 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.002 0.998 0.000
C46 Kaposi's sarcoma
0.002 0.998 0.000
C72.9 Central nervous system, unspecified
0.002 0.998 0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system
0.002 0.998 0.000
C72.5 Other and unspecified cranial nerves
0.002 0.998 0.000
C72.4 Acoustic nerve
0.002 0.998 0.000
C72.3 Optic nerve
0.002 0.998 0.000
C72.2 Olfactory nerve
0.002 0.998 0.000
C72.1 Cauda equina
0.002 0.998 0.000
M10.3 Gout due to impairment of renal function
0.002 0.998 0.000
C48.8 Overlapping lesion of retroperitoneum and peritoneum
0.002 0.998 0.000
F22.0 Delusional disorder
0.002 0.998 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.002 0.998 0.000
A08.1 Acute gastro-enteropathy due to Norwalk agent
0.002 0.998 0.000
C72.0 Spinal cord
0.002 0.998 0.000
M54.16 Radiculopathy (Lumbar region)
0.000 0.998 0.002
M70.65 Trochanteric bursitis-Pelvic/Thigh
0.000 0.998 0.002
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.002 0.998 0.000
K86.2 Cyst of pancreas
0.002 0.998 0.000
B37.1 Pulmonary candidiasis
0.002 0.998 0.000
C69.9 Eye, unspecified
0.002 0.998 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.002 0.998 0.000
Z63.4 Disappearance and death of family member
0.002 0.998 0.000
C69.8 Overlapping lesion of eye and adnexa
0.002 0.998 0.000
C69.5 Lachrymal gland and duct
0.002 0.998 0.000
C69.4 Ciliary body
0.002 0.998 0.000
C69.1 Cornea
0.002 0.998 0.000
C75.1 Pituitary gland
0.002 0.998 0.000
C75.0 Parathyroid gland
0.002 0.998 0.000
J32.0 Chronic maxillary sinusitis
0.000 0.998 0.002
K66.8 Other specified disorders of peritoneum
0.002 0.998 0.000
C69.2 Retina
0.002 0.998 0.000
M10.4 Other secondary gout
0.002 0.998 0.000
M10.2 Drug-induced gout
0.002 0.998 0.000
M10.1 Lead-induced gout
0.002 0.998 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.002 0.998 0.000
R01.1 Cardiac murmur, unspecified
0.000 0.998 0.002
O16 Unspecified maternal hypertension
0.000 0.998 0.002
C75.8 Pluriglandular involvement, unspecified
0.002 0.998 0.000
C75.4 Carotid body
0.002 0.998 0.000
C75.3 Pineal gland
0.002 0.998 0.000
C75.2 Craniopharyngeal duct
0.002 0.998 0.000
M89.04 Algoneurodystrophy (Hand)
0.002 0.998 0.000
M89.03 Algoneurodystrophy (Forearm)
0.002 0.998 0.000
S92.70 Multiple fractures of foot (closed)
0.000 0.998 0.002
M10.39 Gout due to impairment of renal function (Site unspecified)
0.002 0.998 0.000
D25.1 Intramural leiomyoma of uterus
0.002 0.998 0.000
H90.0 Conductive hearing loss, bilateral
0.002 0.998 0.000
B50.9 Plasmodium falciparum malaria, unspecified
0.002 0.998 0.000
M10.0 Idiopathic gout
0.002 0.998 0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.000 0.998 0.002
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.002 0.998 0.000
F50.0 Anorexia nervosa
0.000 0.998 0.002
R46.0 Very low level of personal hygiene
0.000 0.998 0.002
G11.9 Hereditary ataxia, unspecified
0.000 0.998 0.002
N27.0 Small kidney, unilateral
0.002 0.998 0.000
R22.2 Localised swelling, mass and lump, trunk
0.000 0.998 0.002
I08.0 Disorders of both mitral and aortic valves
0.002 0.998 0.000
I97.0 Postcardiotomy syndrome
0.002 0.998 0.000
E66.8 Other obesity
0.002 0.998 0.000
G36.9 Acute disseminated demyelination, unspecified
0.001 0.998 0.000
G36.8 Other specified acute disseminated demyelination
0.001 0.998 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.001 0.998 0.000
J99.8 Respiratory disorders in other diseases classified elsewhere
0.002 0.998 0.000
C46.9 Kaposi's sarcoma, unspecified
0.002 0.998 0.000
C46.8 Kaposi's sarcoma of multiple organs
0.002 0.998 0.000
C46.7 Kaposi's sarcoma of other sites
0.002 0.998 0.000
C46.3 Kaposi's sarcoma of lymph nodes
0.002 0.998 0.000
C46.2 Kaposi's sarcoma of palate
0.002 0.998 0.000
C46.1 Kaposi's sarcoma of soft tissue
0.002 0.998 0.000
C46.0 Kaposi's sarcoma of skin
0.002 0.998 0.000
C47.9 Peripheral nerves and autonomic nervous system, unspecified
0.002 0.998 0.000
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system
0.002 0.998 0.000
C47.6 Peripheral nerves of trunk, unspecified
0.002 0.998 0.000
C47.5 Peripheral nerves of pelvis
0.002 0.998 0.000
C47.4 Peripheral nerves of abdomen
0.002 0.998 0.000
C47.3 Peripheral nerves of thorax
0.002 0.998 0.000
C47.2 Peripheral nerves of lower limb, including hip
0.002 0.998 0.000
C47.1 Peripheral nerves of upper limb, including shoulder
0.002 0.998 0.000
C47.0 Peripheral nerves of head, face and neck
0.002 0.998 0.000
C48.1 Specified parts of peritoneum
0.002 0.998 0.000
C74 Malignant neoplasm of adrenal gland
0.002 0.998 0.000
M10.38 Gout due to impairment of renal function (Other)
0.002 0.998 0.000
M10.37 Gout due to impairment of renal function (Ankle and foot)
0.002 0.998 0.000
M10.36 Gout due to impairment of renal function (Lower leg)
0.002 0.998 0.000
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)
0.002 0.998 0.000
M10.34 Gout due to impairment of renal function (Hand)
0.002 0.998 0.000
M10.33 Gout due to impairment of renal function (Forearm)
0.002 0.998 0.000
M10.32 Gout due to impairment of renal function (Upper arm)
0.002 0.998 0.000
M10.31 Gout due to impairment of renal function (Shoulder region)
0.002 0.998 0.000
M10.30 Gout due to impairment of renal function (Multiple sites)
0.002 0.998 0.000
D38.1 Trachea, bronchus and lung
0.002 0.998 0.000
H90.2 Conductive hearing loss, unspecified
0.002 0.998 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.000 0.998 0.002
C69.0 Conjunctiva
0.002 0.998 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.002 0.998 0.000
Z22.5 Carrier of viral hepatitis
0.002 0.998 0.000
M10.19 Lead-induced gout (Site unspecified)
0.001 0.998 0.000
M10.18 Lead-induced gout (Other)
0.001 0.998 0.000
M10.17 Lead-induced gout (Ankle and foot)
0.001 0.998 0.000
M10.16 Lead-induced gout (Lower leg)
0.001 0.998 0.000
M10.15 Lead-induced gout (Pelvic region and thigh)
0.001 0.998 0.000
M10.14 Lead-induced gout (Hand)
0.001 0.998 0.000
M10.13 Lead-induced gout (Forearm)
0.001 0.998 0.000
M10.12 Lead-induced gout (Upper arm)
0.001 0.998 0.000
M10.11 Lead-induced gout (Shoulder region)
0.001 0.998 0.000
M10.10 Lead-induced gout (Multiple sites)
0.001 0.998 0.000
M10.29 Drug-induced gout (Site unspecified)
0.001 0.998 0.000
M10.28 Drug-induced gout (Other)
0.001 0.998 0.000
M10.27 Drug-induced gout (Ankle and foot)
0.001 0.998 0.000
M10.26 Drug-induced gout (Lower leg)
0.001 0.998 0.000
M10.25 Drug-induced gout (Pelvic region and thigh)
0.001 0.998 0.000
M10.24 Drug-induced gout (Hand)
0.001 0.998 0.000
M10.23 Drug-induced gout (Forearm)
0.001 0.998 0.000
M10.22 Drug-induced gout (Upper arm)
0.001 0.998 0.000
M10.21 Drug-induced gout (Shoulder region)
0.001 0.998 0.000
M10.20 Drug-induced gout (Multiple sites)
0.001 0.998 0.000
M10.49 Other secondary gout (Site unspecified)
0.001 0.998 0.000
M10.48 Other secondary gout (Other)
0.001 0.998 0.000
M10.47 Other secondary gout (Ankle and foot)
0.001 0.998 0.000
M10.46 Other secondary gout (Lower leg)
0.001 0.998 0.000
M10.45 Other secondary gout (Pelvic region and thigh)
0.001 0.998 0.000
M10.44 Other secondary gout (Hand)
0.001 0.998 0.000
M10.43 Other secondary gout (Forearm)
0.001 0.998 0.000
M10.42 Other secondary gout (Upper arm)
0.001 0.998 0.000
M10.41 Other secondary gout (Shoulder region)
0.001 0.998 0.000
M10.40 Other secondary gout (Multiple sites)
0.001 0.998 0.000
C69.3 Choroid
0.002 0.998 0.000
I95.2 Hypotension due to drugs
0.002 0.998 0.000
I97.9 Postprocedural disorder of circulatory system, unspecified
0.002 0.998 0.000
K66.0 Peritoneal adhesions
0.002 0.998 0.000
S36.0 Injury of spleen
0.000 0.998 0.002
K85.2 Alcohol-induced acute pancreatitis
0.000 0.998 0.002
L71.9 Rosacea, unspecified
0.002 0.998 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.000 0.998 0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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