TreeWAS – Variant ID: rs16831514

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C79 Secondary malignant neoplasm of other sites	0.000	0.497	0.503
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.506	0.494
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.507	0.493
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.527	0.473
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.531	0.469
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.532	0.468
C80 Malignant neoplasm without specification of site	0.000	0.545	0.455
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.548	0.452
C77.0 Lymph nodes of head, face and neck	0.000	0.561	0.439
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.579	0.421
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.580	0.420
C77.9 Lymph node, unspecified	0.000	0.593	0.407
C77.8 Lymph nodes of multiple regions	0.000	0.597	0.403
C79.6 Secondary malignant neoplasm of ovary	0.000	0.598	0.402
C77.2 Intra-abdominal lymph nodes	0.000	0.608	0.392
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.612	0.388
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.616	0.384
C78.0 Secondary malignant neoplasm of lung	0.000	0.620	0.380
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.636	0.364
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.636	0.364
C80.9 Malignant neoplasm, unspecified	0.000	0.649	0.351
C77.4 Inguinal and lower limb lymph nodes	0.000	0.651	0.349
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.661	0.339
C77.1 Intrathoracic lymph nodes	0.000	0.668	0.332
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.672	0.328
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.676	0.324
C78.1 Secondary malignant neoplasm of mediastinum	0.000	0.676	0.324
C76 Malignant neoplasm of other and ill-defined sites	0.000	0.677	0.323
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.681	0.319
C78.7 Secondary malignant neoplasm of liver	0.000	0.684	0.316
C77.5 Intrapelvic lymph nodes	0.000	0.711	0.289
C79.2 Secondary malignant neoplasm of skin	0.000	0.745	0.254
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.752	0.248
C76.8 Overlapping lesion of other and ill-defined sites	0.000	0.768	0.231
C76.7 Other ill-defined sites	0.000	0.768	0.231
C76.5 Lower limb	0.000	0.768	0.231
C76.4 Upper limb	0.000	0.768	0.231
C76.3 Pelvis	0.000	0.768	0.231
C76.2 Abdomen	0.000	0.768	0.231
C76.1 Thorax	0.000	0.768	0.231
C78.2 Secondary malignant neoplasm of pleura	0.000	0.798	0.202
C76.0 Head, face and neck	0.000	0.799	0.201
M20-M25 Other joint disorders	0.094	0.906	0.000
M23 Internal derangement of knee	0.094	0.906	0.000
M24 Other specific joint derangements	0.094	0.906	0.000
M23.3 Other meniscus derangements	0.091	0.909	0.000
M25 Other joint disorders, not elsewhere classified	0.090	0.910	0.000
M25.7 Osteophyte	0.088	0.912	0.000
M23.8 Other internal derangements of knee	0.086	0.914	0.000
M23.0 Cystic meniscus	0.085	0.915	0.000
M22 Disorders of patella	0.085	0.915	0.000
M24.1 Other articular cartilage disorders	0.085	0.915	0.000
M31 Other necrotising vasculopathies	0.084	0.915	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.081	0.919	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.080	0.920	0.000
M25.78 Osteophyte (Other)	0.080	0.920	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.080	0.920	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.079	0.921	0.000
M33 Dermatopolymyositis	0.076	0.924	0.000
M24.6 Ankylosis of joint	0.076	0.924	0.000
M24.0 Loose body in joint	0.076	0.924	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.075	0.925	0.000
M25.8 Other specified joint disorders	0.075	0.925	0.000
M31.6 Other giant cell arteritis	0.075	0.925	0.000
M22.4 Chondromalacia patellae	0.075	0.925	0.000
M25.77 Osteophyte (Ankle and foot)	0.074	0.926	0.000
M24.7 Protrusio acetabuli	0.073	0.926	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.073	0.927	0.000
M23.4 Loose body in knee	0.073	0.927	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.073	0.927	0.000
M22.2 Patellofemoral disorders	0.073	0.927	0.000
M24.5 Contracture of joint	0.072	0.928	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.072	0.928	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.071	0.929	0.000
M25.3 Other instability of joint	0.071	0.929	0.000
M23.1 Discoid meniscus (congenital)	0.070	0.930	0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.070	0.930	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.070	0.930	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.069	0.931	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.069	0.931	0.000
M24.2 Disorder of ligament	0.069	0.931	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.068	0.932	0.000
M32 Systemic lupus erythematosus	0.068	0.932	0.000
M30 Polyarteritis nodosa and related conditions	0.068	0.932	0.000
M25.76 Osteophyte (Lower leg)	0.068	0.932	0.000
M31.3 Wegener's granulomatosis	0.068	0.932	0.000
M24.9 Joint derangement, unspecified	0.067	0.933	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.067	0.933	0.000
M25.72 Osteophyte (Upper arm)	0.067	0.933	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.067	0.933	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.067	0.933	0.000
M25.0 Haemarthrosis	0.067	0.933	0.000
M23.9 Internal derangement of knee, unspecified	0.066	0.934	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.066	0.934	0.000
M23.37 Other meniscus derangements-Capsular lig	0.065	0.934	0.000
M25.2 Flail joint	0.065	0.935	0.000
M25.1 Fistula of joint	0.065	0.935	0.000
M25.9 Joint disorder, unspecified	0.064	0.936	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.064	0.936	0.000
M34 Systemic sclerosis	0.064	0.936	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.064	0.936	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.063	0.937	0.000
M25.79 Osteophyte (Site unspecified)	0.063	0.937	0.000
M25.73 Osteophyte (Forearm)	0.063	0.937	0.000
M25.70 Osteophyte (Multiple sites)	0.063	0.937	0.000
M24.02 Loose body in joint (Upper arm)	0.063	0.937	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.063	0.937	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.063	0.937	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.063	0.937	0.000
M22.3 Other derangements of patella	0.062	0.938	0.000
M33.1 Other dermatomyositis	0.062	0.938	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.061	0.938	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.061	0.938	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.061	0.938	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.061	0.938	0.000
M25.83 Other specified joint disorders (Forearm)	0.062	0.938	0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.061	0.939	0.000
M23.07 Cystic meniscus-Capsular lig	0.061	0.939	0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.061	0.939	0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.061	0.939	0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.061	0.939	0.000
M23.00 Cystic meniscus (Multiple sites)	0.061	0.939	0.000
M22.1 Recurrent subluxation of patella	0.061	0.939	0.000
M22.9 Disorder of patella, unspecified	0.061	0.939	0.000
M22.0 Recurrent dislocation of patella	0.061	0.939	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.061	0.939	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.061	0.939	0.000
M24.18 Other articular cartilage disorders (Other)	0.061	0.939	0.000
M24.14 Other articular cartilage disorders (Hand)	0.061	0.939	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.061	0.939	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.061	0.939	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.061	0.939	0.000
M25.74 Osteophyte (Hand)	0.061	0.939	0.000
M31.9 Necrotising vasculopathy, unspecified	0.061	0.939	0.000
M31.8 Other specified necrotising vasculopathies	0.061	0.939	0.000
M31.7 Microscopic polyangiitis	0.061	0.939	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.061	0.939	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.061	0.939	0.000
M31.2 Lethal midline granuloma	0.061	0.939	0.000
M31.1 Thrombotic microangiopathy	0.061	0.939	0.000
M31.0 Hypersensitivity angiitis	0.061	0.939	0.000
M25.71 Osteophyte (Shoulder region)	0.060	0.940	0.000
M23.43 Loose body in knee-Med lig/oth men	0.060	0.940	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.060	0.940	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.059	0.941	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.059	0.941	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.058	0.941	0.000
M25.31 Other instability of joint (Shoulder region)	0.058	0.942	0.000
M23.5 Chronic instability of knee	0.058	0.942	0.000
M33.2 Polymyositis	0.057	0.943	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.057	0.943	0.000
M24.54 Contracture of joint (Hand)	0.056	0.944	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.056	0.944	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.055	0.945	0.000
M33.9 Dermatopolymyositis, unspecified	0.055	0.945	0.000
M33.0 Juvenile dermatomyositis	0.055	0.945	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.055	0.945	0.000
M24.68 Ankylosis of joint (Other)	0.055	0.945	0.000
M24.66 Ankylosis of joint (Lower leg)	0.055	0.945	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.055	0.945	0.000
M24.64 Ankylosis of joint (Hand)	0.055	0.945	0.000
M24.63 Ankylosis of joint (Forearm)	0.055	0.945	0.000
M24.62 Ankylosis of joint (Upper arm)	0.055	0.945	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.055	0.945	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.055	0.945	0.000
M25.84 Other specified joint disorders (Hand)	0.055	0.945	0.000
M22.8 Other disorders of patella	0.055	0.945	0.000
M24.09 Loose body in joint (Site unspecified)	0.054	0.946	0.000
M24.08 Loose body in joint (Other)	0.054	0.946	0.000
M24.06 Loose body in joint-Lower leg	0.054	0.946	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.054	0.946	0.000
M24.04 Loose body in joint (Hand)	0.054	0.946	0.000
M24.03 Loose body in joint (Forearm)	0.054	0.946	0.000
M24.01 Loose body in joint (Shoulder region)	0.054	0.946	0.000
M24.00 Loose body in joint (Multiple sites)	0.054	0.946	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.054	0.946	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.054	0.946	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.054	0.946	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.054	0.946	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.054	0.946	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.054	0.946	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.054	0.946	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.054	0.946	0.000
M25.88 Other specified joint disorders (Other)	0.054	0.946	0.000
M25.82 Other specified joint disorders (Upper arm)	0.054	0.946	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.054	0.946	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.054	0.946	0.000
M24.07 Loose body in joint (Ankle and foot)	0.054	0.946	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.054	0.946	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.054	0.946	0.000
M24.26 Disorder of ligament (Lower leg)	0.053	0.947	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.053	0.947	0.000
M24.79 Protrusio acetabuli-Site unspec	0.053	0.947	0.000
M24.78 Protrusio acetabuli-Other	0.053	0.947	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.053	0.947	0.000
M24.76 Protrusio acetabuli-Lower leg	0.053	0.947	0.000
M24.74 Protrusio acetabuli-Hand	0.053	0.947	0.000
M24.73 Protrusio acetabuli-Forearm	0.053	0.947	0.000
M24.72 Protrusio acetabuli-Upper arm	0.053	0.947	0.000
M24.71 Protrusio acetabuli-Shldr region	0.053	0.947	0.000
M24.70 Protrusio acetabuli-Mult sites	0.053	0.947	0.000
M25.86 Other specified joint disorders (Lower leg)	0.053	0.947	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.053	0.947	0.000
M23.47 Loose body in knee-Capsular lig	0.052	0.948	0.000
M23.46 Loose body in knee-O/unsp lat men	0.052	0.948	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.052	0.948	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.052	0.948	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.052	0.948	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.052	0.948	0.000
M23.40 Loose body in knee-Mult sites	0.052	0.948	0.000
M24.59 Contracture of joint (Site unspecified)	0.052	0.948	0.000
M24.58 Contracture of joint (Other)	0.052	0.948	0.000
M24.57 Contracture of joint (Ankle and foot)	0.052	0.948	0.000
M24.56 Contracture of joint (Lower leg)	0.052	0.948	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.052	0.948	0.000
M24.53 Contracture of joint (Forearm)	0.052	0.948	0.000
M24.52 Contracture of joint (Upper arm)	0.052	0.948	0.000
M24.51 Contracture of joint (Shoulder region)	0.052	0.948	0.000
M24.50 Contracture of joint (Multiple sites)	0.052	0.948	0.000
M25.39 Other instability of joint (Site unspecified)	0.051	0.949	0.000
M25.38 Other instability of joint (Other)	0.051	0.949	0.000
M25.36 Other instability of joint (Lower leg)	0.051	0.949	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.051	0.949	0.000
M25.34 Other instability of joint (Hand)	0.051	0.949	0.000
M25.33 Other instability of joint (Forearm)	0.051	0.949	0.000
M25.32 Other instability of joint (Upper arm)	0.051	0.949	0.000
M25.30 Other instability of joint (Multiple sites)	0.051	0.949	0.000
C77.3 Axillary and upper limb lymph nodes	0.000	0.949	0.051
M25.5 Pain in joint	0.051	0.949	0.000
M25.37 Other instability of joint (Ankle and foot)	0.051	0.949	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.050	0.949	0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.050	0.949	0.000
M23.17 Discoid meniscus (congenital)-Capsular lig	0.050	0.949	0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.050	0.949	0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.050	0.949	0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.050	0.949	0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.050	0.949	0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.050	0.949	0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.050	0.949	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.050	0.949	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.050	0.950	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.050	0.950	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.050	0.950	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.050	0.950	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.050	0.950	0.000
M25.06 Haemarthrosis (Lower leg)	0.050	0.950	0.000
M24.29 Disorder of ligament (Site unspecified)	0.049	0.950	0.000
M24.28 Disorder of ligament (Other)	0.049	0.950	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.049	0.950	0.000
M24.22 Disorder of ligament (Upper arm)	0.049	0.950	0.000
M24.21 Disorder of ligament (Shoulder region)	0.049	0.950	0.000
M24.20 Disorder of ligament (Multiple sites)	0.049	0.950	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.049	0.951	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.049	0.951	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.049	0.951	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.049	0.951	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.049	0.951	0.000
M30.2 Juvenile polyarteritis	0.049	0.951	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.049	0.951	0.000
M30.0 Polyarteritis nodosa	0.049	0.951	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.049	0.951	0.000
M32.8 Other forms of systemic lupus erythematosus	0.049	0.951	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.049	0.951	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.049	0.951	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.049	0.951	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.049	0.951	0.000
M36.3 Arthropathy in other blood disorders	0.049	0.951	0.000
M36.2 Haemophilic arthropathy	0.049	0.951	0.000
M36.1 Arthropathy in neoplastic disease	0.049	0.951	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.049	0.951	0.000
M24.24 Disorder of ligament (Hand)	0.049	0.951	0.000
M34.1 CR(E)ST syndrome	0.049	0.951	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.048	0.951	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.048	0.951	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.048	0.951	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.048	0.951	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.048	0.951	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.048	0.951	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.048	0.951	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.048	0.951	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.048	0.951	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.048	0.951	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.048	0.951	0.000
M24.98 Joint derangement, unspecified (Other)	0.048	0.951	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.048	0.951	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.048	0.951	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.048	0.951	0.000
M24.94 Joint derangement, unspecified (Hand)	0.048	0.951	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.048	0.951	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.048	0.951	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.048	0.951	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.048	0.951	0.000
M23.49 Loose body in knee-Unspec lig/men	0.048	0.951	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.048	0.952	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.048	0.952	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.048	0.952	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.048	0.952	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.048	0.952	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.048	0.952	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.048	0.952	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.048	0.952	0.000
M25.4 Effusion of joint	0.048	0.952	0.000
M25.09 Haemarthrosis (Site unspecified)	0.048	0.952	0.000
M25.08 Haemarthrosis (Other)	0.048	0.952	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.048	0.952	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.048	0.952	0.000
M25.04 Haemarthrosis (Hand)	0.048	0.952	0.000
M25.03 Haemarthrosis (Forearm)	0.048	0.952	0.000
M25.02 Haemarthrosis (Upper arm)	0.048	0.952	0.000
M25.01 Haemarthrosis (Shoulder region)	0.048	0.952	0.000
M25.00 Haemarthrosis (Multiple sites)	0.048	0.952	0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.048	0.952	0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.048	0.952	0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.048	0.952	0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.048	0.952	0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.048	0.952	0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.048	0.952	0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.048	0.952	0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.048	0.952	0.000
M25.19 Fistula of joint (Site unspecified)	0.047	0.953	0.000
M25.18 Fistula of joint (Other)	0.047	0.953	0.000
M25.17 Fistula of joint (Ankle and foot)	0.047	0.953	0.000
M25.16 Fistula of joint (Lower leg)	0.047	0.953	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.047	0.953	0.000
M25.14 Fistula of joint (Hand)	0.047	0.953	0.000
M25.13 Fistula of joint (Forearm)	0.047	0.953	0.000
M25.12 Fistula of joint (Upper arm)	0.047	0.953	0.000
M25.11 Fistula of joint (Shoulder region)	0.047	0.953	0.000
M25.10 Fistula of joint (Multiple sites)	0.047	0.953	0.000
M25.29 Flail joint (Site unspecified)	0.047	0.953	0.000
M25.28 Flail joint (Other)	0.047	0.953	0.000
M25.27 Flail joint (Ankle and foot)	0.047	0.953	0.000
M25.26 Flail joint (Lower leg)	0.047	0.953	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.047	0.953	0.000
M25.24 Flail joint (Hand)	0.047	0.953	0.000
M25.23 Flail joint (Forearm)	0.047	0.953	0.000
M25.22 Flail joint (Upper arm)	0.047	0.953	0.000
M25.21 Flail joint (Shoulder region)	0.047	0.953	0.000
M25.20 Flail joint (Multiple sites)	0.047	0.953	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.047	0.953	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.046	0.953	0.000
M24.23 Disorder of ligament (Forearm)	0.046	0.954	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.046	0.954	0.000
M25.98 Joint disorder, unspecified (Other)	0.046	0.954	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.046	0.954	0.000
M25.94 Joint disorder, unspecified (Hand)	0.046	0.954	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.046	0.954	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.046	0.954	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.046	0.954	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.046	0.954	0.000
M34.8 Other forms of systemic sclerosis	0.046	0.954	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.046	0.954	0.000
M34.0 Progressive systemic sclerosis	0.046	0.954	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.046	0.954	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.045	0.955	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.044	0.955	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.044	0.956	0.000
M25.57 Pain in joint (Ankle and foot)	0.044	0.956	0.000
M25.58 Pain in joint (Other)	0.043	0.957	0.000
M35 Other systemic involvement of connective tissue	0.043	0.957	0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.042	0.958	0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.042	0.958	0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.042	0.958	0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.042	0.958	0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.042	0.958	0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.042	0.958	0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.042	0.958	0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.042	0.958	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.042	0.958	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.042	0.958	0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.042	0.958	0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.042	0.958	0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.042	0.958	0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.042	0.958	0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.042	0.958	0.000
M23.50 Chronic instability of knee (Multiple sites)	0.042	0.958	0.000
M25.53 Pain in joint (Forearm)	0.041	0.959	0.000
M25.51 Pain in joint (Shoulder region)	0.039	0.961	0.000
M25.40 Effusion of joint (Multiple sites)	0.038	0.962	0.000
M34.9 Systemic sclerosis, unspecified	0.037	0.962	0.000
M25.59 Pain in joint (Site unspecified)	0.037	0.963	0.000
M25.42 Effusion of joint (Upper arm)	0.037	0.963	0.000
M25.50 Pain in joint (Multiple sites)	0.037	0.963	0.000
M25.52 Pain in joint (Upper arm)	0.035	0.964	0.000
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.035	0.965	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.035	0.965	0.000
M25.49 Effusion of joint (Site unspecified)	0.035	0.965	0.000
M25.48 Effusion of joint (Other)	0.035	0.965	0.000
M25.44 Effusion of joint (Hand)	0.035	0.965	0.000
M25.43 Effusion of joint (Forearm)	0.035	0.965	0.000
M25.41 Effusion of joint (Shoulder region)	0.035	0.965	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.033	0.967	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.033	0.967	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.032	0.968	0.000
M21 Other acquired deformities of limbs	0.031	0.969	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.031	0.969	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.031	0.969	0.000
M35.8 Other specified systemic involvement of connective tissue	0.031	0.969	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.031	0.969	0.000
M35.5 Multifocal fibrosclerosis	0.031	0.969	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.031	0.969	0.000
M35.2 Behcet's disease	0.031	0.969	0.000
M35.1 Other overlap syndromes	0.031	0.969	0.000
M35.0 Sicca syndrome [Sjogren]	0.031	0.969	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.030	0.970	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.030	0.970	0.000
M35.7 Hypermobility syndrome	0.030	0.970	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.028	0.972	0.000
M50-M54 Other dorsopathies	0.028	0.972	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.027	0.973	0.000
M91-M94 Chondropathies	0.027	0.973	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.027	0.973	0.000
M80-M85 Disorders of bone density and structure	0.026	0.974	0.000
M72 Fibroblastic disorders	0.026	0.974	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.026	0.974	0.000
M25.54 Pain in joint (Hand)	0.025	0.975	0.000
M60-M63 Disorders of muscles	0.025	0.975	0.000
M50 Cervical disk disorders	0.025	0.975	0.000
M70-M79 Other soft tissue disorders	0.024	0.976	0.000
M25.46 Effusion of joint (Lower leg)	0.024	0.976	0.000
M65-M68 Disorders of synovium and tendon	0.024	0.976	0.000
M72.2 Plantar fascial fibromatosis	0.024	0.976	0.000
M50.2 Other cervical disk displacement	0.023	0.977	0.000
M51 Other intervertebral disk disorders	0.023	0.977	0.000
M81 Osteoporosis without pathological fracture	0.023	0.977	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.023	0.977	0.000
M21.9 Acquired deformity of limb, unspecified	0.022	0.977	0.000
M21.8 Other specified acquired deformities of limbs	0.022	0.977	0.000
M21.7 Unequal limb length (acquired)	0.022	0.977	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.023	0.977	0.000
M00-M03 Infectious arthropathies	0.023	0.977	0.000
M99 Biomechanical lesions, not elsewhere classified	0.023	0.977	0.000
M92 Other juvenile osteochondrosis	0.023	0.977	0.000
M21.3 Wrist or foot drop (acquired)	0.022	0.977	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.022	0.978	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.022	0.978	0.000
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.022	0.978	0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.022	0.978	0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.022	0.978	0.000
M96.5 Postradiation scoliosis	0.022	0.978	0.000
M96.4 Postsurgical lordosis	0.022	0.978	0.000
M96.3 Postlaminectomy kyphosis	0.022	0.978	0.000
M96.2 Postradiation kyphosis	0.022	0.978	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.022	0.978	0.000
M21.4 Flat foot [pes planus] (acquired)	0.021	0.978	0.000
M86-M90 Other osteopathies	0.021	0.979	0.000
M40-M43 Deforming dorsopathies	0.021	0.979	0.000
M51.2 Other specified intervertebral disk displacement	0.021	0.979	0.000
M80 Osteoporosis with pathological fracture	0.021	0.979	0.000
M81.9 Osteoporosis, unspecified	0.021	0.979	0.000
M21.2 Flexion deformity	0.020	0.979	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.021	0.979	0.000
M25.47 Effusion of joint (Ankle and foot)	0.020	0.980	0.000
M94 Other disorders of cartilage	0.020	0.980	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.020	0.980	0.000
M65 Synovitis and tenosynovitis	0.020	0.980	0.000
M21.1 Varus deformity, not elsewhere classified	0.020	0.980	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.020	0.980	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.019	0.980	0.000
M92.6 Juvenile osteochondrosis of tarsus	0.019	0.980	0.000
M51.3 Other specified intervertebral disk degeneration	0.019	0.981	0.000
M50.3 Other cervical disk degeneration	0.019	0.981	0.000
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.019	0.981	0.000
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other	0.019	0.981	0.000
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot	0.019	0.981	0.000
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg	0.019	0.981	0.000
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh	0.019	0.981	0.000
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm	0.019	0.981	0.000
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm	0.019	0.981	0.000
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region	0.019	0.981	0.000
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites	0.019	0.981	0.000
M76 Enthesopathies of lower limb, excluding foot	0.019	0.981	0.000
M21.6 Other acquired deformities of ankle and foot	0.019	0.981	0.001
M50.9 Cervical disk disorder, unspecified	0.019	0.981	0.000
M83 Adult osteomalacia	0.019	0.981	0.000
M53 Other dorsopathies, not elsewhere classified	0.019	0.981	0.000
M72.9 Fibroblastic disorder, unspecified	0.019	0.981	0.000
M72.8 Other fibroblastic disorders	0.019	0.981	0.000
M72.6 Necrotizing fasciitis	0.019	0.981	0.000
M72.5 Fasciitis, not elsewhere classified	0.019	0.981	0.000
M72.4 Pseudosarcomatous fibromatosis	0.019	0.981	0.000
M72.3 Nodular fasciitis	0.019	0.981	0.000
M72.1 Knuckle pads	0.019	0.981	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.019	0.981	0.000
M62 Other disorders of muscle	0.019	0.981	0.000
M21.0 Valgus deformity, not elsewhere classified	0.019	0.981	0.000
M05-M14 Inflammatory polyarthropathies	0.019	0.981	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.019	0.981	0.000
M93 Other osteochondropathies	0.019	0.981	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.018	0.982	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.018	0.982	0.000
M82 Osteoporosis in diseases classified elsewhere	0.018	0.982	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.018	0.982	0.000
M61 Calcification and ossification of muscle	0.018	0.982	0.000
M60 Myositis	0.018	0.982	0.000
M50.8 Other cervical disk disorders	0.018	0.982	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.018	0.982	0.000
M66 Spontaneous rupture of synovium and tendon	0.018	0.982	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.018	0.982	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.018	0.982	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations