TreeWAS – Variant ID: rs16875528

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001	0.000
M50-M54 Other dorsopathies	0.997	0.003	0.000
M54 Dorsalgia	0.995	0.005	0.000
Chapter X Diseases of the respiratory system	0.990	0.010	0.000
# Top node	0.989	0.011	0.000
M70-M79 Other soft tissue disorders	0.989	0.011	0.000
M54.5 Low back pain	0.985	0.015	0.000
J30-J39 Other diseases of upper respiratory tract	0.979	0.021	0.000
J34 Other disorders of nose and nasal sinuses	0.971	0.029	0.000
J40-J47 Chronic lower respiratory diseases	0.968	0.032	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.966	0.034	0.000
J44 Other chronic obstructive pulmonary disease	0.963	0.037	0.000
J34.3 Hypertrophy of nasal turbinates	0.962	0.038	0.000
Chapter XX External causes of morbidity and mortality	0.961	0.039	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.955	0.045	0.000
M54.59 Low back pain (Site unspecified)	0.951	0.049	0.000
M05-M14 Inflammatory polyarthropathies	0.932	0.068	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.928	0.072	0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.912	0.088	0.000
M79.7 Fibromyalgia	0.908	0.092	0.000
M80-M85 Disorders of bone density and structure	0.902	0.098	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.896	0.104	0.000
S20-S29 Injuries to the thorax	0.888	0.112	0.000
M13 Other arthritis	0.885	0.115	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.882	0.118	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.882	0.118	0.000
M54.56 Low back pain (Lumbar region)	0.881	0.119	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.878	0.122	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.877	0.123	0.000
M51 Other intervertebral disk disorders	0.876	0.124	0.000
M54.2 Cervicalgia	0.868	0.132	0.000
M79.79 Fibromyalgia (Site unspecified)	0.868	0.132	0.000
M79.6 Pain in limb	0.867	0.133	0.000
M54.57 Low back pain (Lumbosacral region)	0.864	0.136	0.000
M72 Fibroblastic disorders	0.859	0.141	0.000
Chapter XIV Diseases of the genitourinary system	0.856	0.144	0.000
M54.9 Dorsalgia, unspecified	0.852	0.148	0.000
M13.9 Arthritis, unspecified	0.851	0.149	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.851	0.149	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.843	0.157	0.000
N20-N23 Urolithiasis	0.838	0.162	0.000
Y83.8 Other surgical procedures	0.837	0.163	0.000
M15-M19 Arthrosis	0.833	0.167	0.000
J30 Vasomotor and allergic rhinitis	0.833	0.167	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.832	0.168	0.000
J84 Other interstitial pulmonary diseases	0.828	0.172	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.828	0.172	0.000
L20-L30 Dermatitis and eczema	0.826	0.174	0.000
M75 Shoulder lesions	0.823	0.177	0.000
M79.66 Pain in limb (Lower leg)	0.823	0.177	0.000
J34.2 Deviated nasal septum	0.817	0.183	0.000
M17 Gonarthrosis [arthrosis of knee]	0.815	0.185	0.000
Y83.6 Removal of other organ (partial) (total)	0.815	0.185	0.000
S70-S79 Injuries to the hip and thigh	0.814	0.186	0.000
N20 Calculus of kidney and ureter	0.811	0.189	0.000
M17.1 Other primary gonarthrosis	0.811	0.189	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.810	0.189	0.000
M54.1 Radiculopathy	0.805	0.195	0.000
J34.1 Cyst and mucocele of nose and nasal sinus	0.804	0.196	0.000
J33 Nasal polyp	0.803	0.197	0.000
M81 Osteoporosis without pathological fracture	0.801	0.199	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.799	0.201	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.798	0.202	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.796	0.204	0.000
J00-J06 Acute upper respiratory infections	0.792	0.208	0.000
M05 Seropositive rheumatoid arthritis	0.791	0.209	0.000
M13.99 Arthritis, unspecified (Site unspecified)	0.790	0.210	0.000
Chapter VIII Diseases of the ear and mastoid process	0.789	0.211	0.000
M51.2 Other specified intervertebral disk displacement	0.788	0.212	0.000
M45-M49 Spondylopathies	0.786	0.214	0.000
J43 Emphysema	0.783	0.217	0.000
M54.6 Pain in thoracic spine	0.779	0.221	0.000
N20.1 Calculus of ureter	0.779	0.221	0.000
S50-S59 Injuries to the elbow and forearm	0.777	0.223	0.000
M54.22 Cervicalgia (Cervical region)	0.777	0.223	0.000
L30 Other dermatitis	0.775	0.225	0.000
N25-N29 Other disorders of kidney and ureter	0.772	0.228	0.000
Y83.1 Surgical operation with implant of artificial internal device	0.772	0.228	0.000
W00-W19 Falls	0.771	0.229	0.000
N10-N16 Renal tubulo-interstitial diseases	0.768	0.232	0.000
M75.5 Bursitis of shoulder	0.767	0.233	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.766	0.234	0.000
M79.0 Rheumatism, unspecified	0.765	0.235	0.000
T66-T78 Other and unspecified effects of external causes	0.759	0.241	0.000
S22.0 Fracture of thoracic vertebra	0.757	0.243	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.757	0.243	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.756	0.244	0.000
M13.96 Arthritis, unspecified (Lower leg)	0.753	0.247	0.000
Chapter VI Diseases of the nervous system	0.753	0.247	0.000
J90-J94 Other diseases of pleura	0.751	0.249	0.000
M00-M03 Infectious arthropathies	0.749	0.251	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.746	0.254	0.000
M54.4 Lumbago with sciatica	0.744	0.256	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.742	0.258	0.000
L30.9 Dermatitis, unspecified	0.738	0.262	0.000
S90-S99 Injuries to the ankle and foot	0.733	0.267	0.000
Y95 Nosocomial condition	0.732	0.268	0.000
N23 Unspecified renal colic	0.730	0.270	0.000
M81.9 Osteoporosis, unspecified	0.729	0.271	0.000
J30.1 Allergic rhinitis due to pollen	0.728	0.272	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.728	0.272	0.000
J42 Unspecified chronic bronchitis	0.728	0.272	0.000
M86-M90 Other osteopathies	0.728	0.272	0.000
T81 Complications of procedures, not elsewhere classified	0.727	0.273	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.726	0.274	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.725	0.275	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.725	0.275	0.000
N20.0 Calculus of kidney	0.725	0.275	0.000
S10-S19 Injuries to the neck	0.723	0.277	0.000
Y83.3 Surgical operation with formation of external stoma	0.722	0.278	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.720	0.280	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.719	0.281	0.000
J86 Pyothorax	0.719	0.281	0.000
Chapter I Certain infectious and parasitic diseases	0.717	0.283	0.000
M91-M94 Chondropathies	0.716	0.283	0.000
M60-M63 Disorders of muscles	0.716	0.283	0.000
S40-S49 Injuries to the shoulder and upper arm	0.716	0.284	0.000
M53 Other dorsopathies, not elsewhere classified	0.715	0.285	0.000
Y83.0 Surgical operation with transplant of whole organ	0.714	0.286	0.000
M40-M43 Deforming dorsopathies	0.714	0.286	0.000
M54.8 Other dorsalgia	0.713	0.286	0.000
M54.0 Panniculitis affecting regions of neck and back	0.713	0.286	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.713	0.287	0.000
L82 Seborrhoeic keratosis	0.713	0.287	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.713	0.287	0.000
H65-H75 Diseases of middle ear and mastoid	0.711	0.289	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.709	0.291	0.000
M76 Enthesopathies of lower limb, excluding foot	0.709	0.291	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.709	0.291	0.000
M71 Other bursopathies	0.709	0.291	0.000
L50-L54 Urticaria and erythema	0.708	0.292	0.000
M77 Other enthesopathies	0.708	0.292	0.000
M54.55 Low back pain (Thoracolumbar region)	0.706	0.294	0.000
M54.54 Low back pain-Thoracic	0.706	0.294	0.000
M54.53 Low back pain-Cervicothoracic	0.706	0.294	0.000
M54.52 Low back pain-Cervical	0.706	0.294	0.000
M54.51 Low back pain-Occipit-atl-axl	0.706	0.294	0.000
M54.50 Low back pain (Multiple sites in spine)	0.706	0.294	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.704	0.296	0.000
M13.94 Arthritis, unspecified (Hand)	0.704	0.296	0.000
T81.4 Infection following a procedure, not elsewhere classified	0.703	0.297	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.702	0.298	0.000
J33.0 Polyp of nasal cavity	0.702	0.298	0.000
J37 Chronic laryngitis and laryngotracheitis	0.702	0.298	0.000
M84 Disorders of continuity of bone	0.701	0.299	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.699	0.301	0.000
J47 Bronchiectasis	0.699	0.301	0.000
N99-N99 Other disorders of the genitourinary system	0.699	0.301	0.000
J34.0 Abscess, furuncle and carbuncle of nose	0.696	0.303	0.000
J41 Simple and mucopurulent chronic bronchitis	0.694	0.306	0.000
M79.9 Soft tissue disorder, unspecified	0.692	0.308	0.000
M79.5 Residual foreign body in soft tissue	0.692	0.308	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.692	0.308	0.000
M79.3 Panniculitis, unspecified	0.692	0.308	0.000
M79.2 Neuralgia and neuritis, unspecified	0.692	0.308	0.000
M79.1 Myalgia	0.692	0.308	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.689	0.311	0.000
Y35-Y36 Legal intervention and operations of war	0.689	0.311	0.000
Y10-Y34 Event of undetermined intent	0.689	0.311	0.000
Y00-Y09 Assault	0.689	0.311	0.000
X85-X99 Assault	0.689	0.311	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.689	0.311	0.000
X50-X57 Overexertion, travel and privation	0.689	0.311	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.689	0.311	0.000
X30-X39 Exposure to forces of nature	0.689	0.311	0.000
X20-X29 Contact with venomous animals and plants	0.689	0.311	0.000
X10-X19 Contact with heat and hot substances	0.689	0.311	0.000
X00-X09 Exposure to smoke, fire and flames	0.689	0.311	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.689	0.311	0.000
W75-W84 Other accidental threats to breathing	0.689	0.311	0.000
W65-W74 Accidental drowning and submersion	0.689	0.311	0.000
W50-W64 Exposure to animate mechanical forces	0.689	0.311	0.000
V98-V99 Other and unspecified transport accidents	0.689	0.311	0.000
V95-V97 Air and space transport accidents	0.689	0.311	0.000
V90-V94 Water transport accidents	0.689	0.311	0.000
V80-V89 Other land transport accidents	0.689	0.311	0.000
V70-V79 Bus occupant injured in transport accident	0.689	0.311	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.689	0.311	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.689	0.311	0.000
V40-V49 Car occupant injured in transport accident	0.689	0.311	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.689	0.311	0.000
V01-V09 Pedestrian injured in transport accident	0.689	0.311	0.000
L29 Pruritus	0.689	0.311	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.689	0.311	0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.688	0.312	0.000
N28.8 Other specified disorders of kidney and ureter	0.687	0.313	0.000
Y83.2 Surgical operation with anastomosis, bypass or graft	0.687	0.313	0.000
M65-M68 Disorders of synovium and tendon	0.686	0.313	0.000
S80-S89 Injuries to the knee and lower leg	0.686	0.314	0.000
M80 Osteoporosis with pathological fracture	0.685	0.315	0.000
T79-T79 Certain early complications of trauma	0.685	0.315	0.000
T33-T35 Frostbite	0.685	0.315	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.685	0.315	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.685	0.315	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.685	0.315	0.000
T00-T07 Injuries involving multiple body regions	0.685	0.315	0.000
S72 Fracture of femur	0.684	0.316	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.683	0.317	0.000
S29 Other and unspecified injuries of thorax	0.682	0.318	0.000
V20-V29 Motorcycle rider injured in transport accident	0.679	0.321	0.000
J95-J99 Other diseases of the respiratory system	0.675	0.325	0.000
Chapter V Mental and behavioural disorders	0.675	0.325	0.000
T86 Failure and rejection of transplanted organs and tissues	0.673	0.327	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.673	0.327	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.672	0.327	0.000
S27 Injury of other and unspecified intrathoracic organs	0.671	0.328	0.000
M14 Arthropathies in other diseases classified elsewhere	0.668	0.332	0.000
M12 Other specific arthropathies	0.668	0.332	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.668	0.332	0.000
M08 Juvenile arthritis	0.668	0.332	0.000
X60-X84 Intentional self-harm	0.668	0.332	0.000
Chapter XXII Codes for special purposes	0.667	0.332	0.000
V10-V19 Pedal cyclist injured in transport accident	0.666	0.334	0.000
S20 Superficial injury of thorax	0.665	0.335	0.000
J06 Acute upper respiratory infections of multiple and unspecified sites	0.665	0.335	0.000
G20-G26 Extrapyramidal and movement disorders	0.665	0.335	0.000
M79.8 Other specified soft tissue disorders	0.663	0.337	0.000
J60-J70 Lung diseases due to external agents	0.661	0.339	0.000
M13.98 Arthritis, unspecified (Other)	0.659	0.341	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.656	0.343	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.655	0.345	0.000
M06 Other rheumatoid arthritis	0.655	0.345	0.000
Y83.5 Amputation of limb(s)	0.654	0.346	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.654	0.346	0.000
M79.78 Fibromyalgia (Other)	0.651	0.349	0.000
M79.77 Fibromyalgia (Ankle and foot)	0.651	0.349	0.000
M79.76 Fibromyalgia (Lower leg)	0.651	0.349	0.000
M79.75 Fibromyalgia (Pelvic region and thigh)	0.651	0.349	0.000
M79.74 Fibromyalgia (Hand)	0.651	0.349	0.000
M79.73 Fibromyalgia (Forearm)	0.651	0.349	0.000
M79.72 Fibromyalgia (Upper arm)	0.651	0.349	0.000
M79.71 Fibromyalgia (Shoulder region)	0.651	0.349	0.000
M79.70 Fibromyalgia (Multiple sites)	0.651	0.349	0.000
J43.9 Emphysema, unspecified	0.650	0.350	0.000
J03 Acute tonsillitis	0.647	0.352	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.647	0.353	0.000
M83 Adult osteomalacia	0.646	0.354	0.000
M82 Osteoporosis in diseases classified elsewhere	0.646	0.354	0.000
J38.7 Other diseases of larynx	0.645	0.355	0.000
M79.60 Pain in limb (Multiple sites)	0.644	0.356	0.000
M13.0 Polyarthritis, unspecified	0.644	0.356	0.000
L85 Other epidermal thickening	0.642	0.358	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.639	0.361	0.000
N13 Obstructive and reflux uropathy	0.639	0.361	0.000
J86.9 Pyothorax without fistula	0.638	0.362	0.000
M51.8 Other specified intervertebral disk disorders	0.638	0.362	0.000
M79.64 Pain in limb (Hand)	0.637	0.362	0.000
M54.12 Radiculopathy (Cervical region)	0.637	0.363	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.637	0.363	0.000
S26 Injury of heart	0.637	0.363	0.000
S25 Injury of blood vessels of thorax	0.637	0.363	0.000
S24 Injury of nerves and spinal cord at thorax level	0.637	0.363	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.637	0.363	0.000
S21 Open wound of thorax	0.637	0.363	0.000
J09-J18 Influenza and pneumonia	0.636	0.364	0.000
S71 Open wound of hip and thigh	0.635	0.364	0.000
M85 Other disorders of bone density and structure	0.635	0.365	0.000
M13.8 Other specified arthritis	0.635	0.365	0.000
M13.1 Monoarthritis, not elsewhere classified	0.635	0.365	0.000
M11 Other crystal arthropathies	0.635	0.365	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.632	0.368	0.000
J80 Adult respiratory distress syndrome	0.632	0.368	0.000
L10-L14 Bullous disorders	0.632	0.368	0.000
M75.2 Bicipital tendinitis	0.631	0.369	0.000
T87 Complications peculiar to reattachment and amputation	0.629	0.370	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.629	0.370	0.000
M51.3 Other specified intervertebral disk degeneration	0.628	0.372	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.628	0.372	0.000
M51.9 Intervertebral disk disorder, unspecified	0.628	0.372	0.000
M51.4 Schmorl's nodes	0.628	0.372	0.000
H72 Perforation of tympanic membrane	0.627	0.373	0.000
M46 Other inflammatory spondylopathies	0.626	0.374	0.000
M07 Psoriatic and enteropathic arthropathies	0.625	0.375	0.000
Y83.9 Surgical procedure, unspecified	0.624	0.376	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.624	0.376	0.000
N00-N08 Glomerular diseases	0.623	0.377	0.000
M54.29 Cervicalgia-Site unspe	0.622	0.378	0.000
M54.28 Cervicalgia-Sacral/sacrococ	0.622	0.378	0.000
M54.27 Cervicalgia-Lumbosacral	0.622	0.378	0.000
M54.26 Cervicalgia-Lumbar	0.622	0.378	0.000
M54.25 Cervicalgia-Thoracolumbar	0.622	0.378	0.000
M54.24 Cervicalgia-Thoracic	0.622	0.378	0.000
M54.23 Cervicalgia (Cervicothoracic region)	0.622	0.378	0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.622	0.378	0.000
M54.20 Cervicalgia-Mult site	0.622	0.378	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.622	0.378	0.000
N60-N64 Disorders of breast	0.622	0.378	0.000
M79.68 Pain in limb (Other)	0.622	0.378	0.000
M79.61 Pain in limb (Shoulder region)	0.622	0.378	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.622	0.378	0.000
L81 Other disorders of pigmentation	0.621	0.379	0.000
M47 Spondylosis	0.621	0.379	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.620	0.380	0.000
M75.0 Adhesive capsulitis of shoulder	0.620	0.380	0.000
M79.63 Pain in limb (Forearm)	0.620	0.380	0.000
M54.16 Radiculopathy (Lumbar region)	0.619	0.381	0.000
T78 Adverse effects, not elsewhere classified	0.618	0.382	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.617	0.382	0.000
J92 Pleural plaque	0.617	0.382	0.000
M54.3 Sciatica	0.617	0.383	0.000
W20-W49 Exposure to inanimate mechanical forces	0.617	0.383	0.000
M72.9 Fibroblastic disorder, unspecified	0.616	0.384	0.000
M72.8 Other fibroblastic disorders	0.616	0.384	0.000
M72.6 Necrotizing fasciitis	0.616	0.384	0.000
M72.5 Fasciitis, not elsewhere classified	0.616	0.384	0.000
M72.4 Pseudosarcomatous fibromatosis	0.616	0.384	0.000
M72.3 Nodular fasciitis	0.616	0.384	0.000
M72.2 Plantar fascial fibromatosis	0.616	0.384	0.000
M72.1 Knuckle pads	0.616	0.384	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.616	0.384	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.611	0.389	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.611	0.389	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.611	0.389	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.611	0.389	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.611	0.389	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.611	0.389	0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.611	0.389	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.611	0.389	0.000
M13.93 Arthritis, unspecified (Forearm)	0.610	0.390	0.000
M13.92 Arthritis, unspecified (Upper arm)	0.610	0.390	0.000
S52 Fracture of forearm	0.610	0.390	0.000
M81.98 Osteoporosis, unspecified (Other)	0.608	0.391	0.000
L29.0 Pruritus ani	0.608	0.392	0.000
S51 Open wound of forearm	0.607	0.393	0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.606	0.394	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.605	0.395	0.000
M79.69 Pain in limb (Site unspecified)	0.604	0.396	0.000
J39 Other diseases of upper respiratory tract	0.603	0.397	0.000
J38.0 Paralysis of vocal cords and larynx	0.603	0.397	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.603	0.397	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.602	0.397	0.000
M45 Ankylosing spondylitis	0.602	0.398	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.601	0.399	0.000
J38.2 Nodules of vocal cords	0.601	0.399	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.599	0.401	0.000
J35 Chronic diseases of tonsils and adenoids	0.599	0.401	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.598	0.402	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.598	0.402	0.000
J01 Acute sinusitis	0.597	0.403	0.000
M15 Polyarthrosis	0.597	0.403	0.000
N21 Calculus of lower urinary tract	0.597	0.403	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.597	0.403	0.000
J30.4 Allergic rhinitis, unspecified	0.597	0.403	0.000
J30.3 Other allergic rhinitis	0.597	0.403	0.000
J30.2 Other seasonal allergic rhinitis	0.597	0.403	0.000
J30.0 Vasomotor rhinitis	0.597	0.403	0.000
J85 Abscess of lung and mediastinum	0.596	0.403	0.000
W19 Unspecified fall	0.595	0.405	0.000
S22.4 Multiple fractures of ribs	0.594	0.406	0.000
M75.3 Calcific tendinitis of shoulder	0.594	0.406	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.594	0.406	0.000
J84.8 Other specified interstitial pulmonary diseases	0.594	0.406	0.000
J84.0 Alveolar and parietoalveolar conditions	0.594	0.406	0.000
H65 Nonsuppurative otitis media	0.594	0.406	0.000
Y91 Evidence of alcohol involvement determined by level of intoxication	0.593	0.406	0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.593	0.406	0.000
Y98 Lifestyle-related condition	0.593	0.406	0.000
Y97 Environmental-pollution-related condition	0.593	0.406	0.000
Y96 Work-related condition	0.593	0.406	0.000
G90-G99 Other disorders of the nervous system	0.593	0.407	0.000
L25 Unspecified contact dermatitis	0.592	0.407	0.000
L24 Irritant contact dermatitis	0.592	0.407	0.000
L23 Allergic contact dermatitis	0.592	0.407	0.000
L21 Seborrhoeic dermatitis	0.592	0.407	0.000
L20 Atopic dermatitis	0.592	0.407	0.000
L26 Exfoliative dermatitis	0.592	0.407	0.000
L22 Diaper [napkin] dermatitis	0.592	0.407	0.000
M79.62 Pain in limb (Upper arm)	0.591	0.409	0.000
L28 Lichen simplex chronicus and prurigo	0.591	0.409	0.000
J36 Peritonsillar abscess	0.591	0.409	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.591	0.409	0.000
M75.8 Other shoulder lesions	0.590	0.410	0.000
M75.9 Shoulder lesion, unspecified	0.590	0.410	0.000
J38.4 Oedema of larynx	0.588	0.411	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.587	0.413	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.586	0.414	0.000
J46 Status asthmaticus	0.585	0.414	0.000
M17.0 Primary gonarthrosis, bilateral	0.585	0.415	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.585	0.415	0.000
M17.5 Other secondary gonarthrosis	0.584	0.416	0.000
M17.4 Other secondary gonarthrosis, bilateral	0.584	0.416	0.000
M17.3 Other posttraumatic gonarthrosis	0.584	0.416	0.000
M17.2 Posttraumatic gonarthrosis, bilateral	0.584	0.416	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.584	0.416	0.000
S79 Other and unspecified injuries of hip and thigh	0.584	0.416	0.000
S78 Traumatic amputation of hip and thigh	0.584	0.416	0.000
S77 Crushing injury of hip and thigh	0.584	0.416	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.584	0.416	0.000
S75 Injury of blood vessels at hip and thigh level	0.584	0.416	0.000
S74 Injury of nerves at hip and thigh level	0.584	0.416	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.584	0.416	0.000
S70 Superficial injury of hip and thigh	0.584	0.416	0.000
J33.9 Nasal polyp, unspecified	0.582	0.418	0.000
N20.9 Urinary calculus, unspecified	0.581	0.418	0.000
S22.9 Fracture of bony thorax, part unspecified	0.581	0.419	0.000
S22.8 Fracture of other parts of bony thorax	0.581	0.419	0.000
S22.5 Flail chest	0.581	0.419	0.000
S22.1 Multiple fractures of thoracic spine	0.581	0.419	0.000
L91 Hypertrophic disorders of skin	0.580	0.420	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.579	0.421	0.000
J94 Other pleural conditions	0.577	0.423	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.577	0.423	0.000
W10 Fall on and from stairs and steps	0.577	0.423	0.000
M54.19 Radiculopathy (Site unspecified)	0.577	0.423	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.577	0.423	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.577	0.423	0.000
M54.15 Radiculopathy (Thoracolumbar region)	0.577	0.423	0.000
M54.14 Radiculopathy (Thoracic region)	0.577	0.423	0.000
M54.13 Radiculopathy (Cervicothoracic region)	0.577	0.423	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.577	0.423	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.577	0.423	0.000
Y83.4 Other reconstructive surgery	0.576	0.424	0.000
J33.1 Polypoid sinus degeneration	0.575	0.424	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.575	0.425	0.000
M81.8 Other osteoporosis	0.574	0.425	0.000
M81.6 Localised osteoporosis [Lequesne]	0.574	0.425	0.000
M81.5 Idiopathic osteoporosis	0.574	0.425	0.000
M81.4 Drug-induced osteoporosis	0.574	0.425	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.574	0.425	0.000
M81.2 Osteoporosis of disuse	0.574	0.425	0.000
M81.1 Postoophorectomy osteoporosis	0.574	0.425	0.000
M81.0 Postmenopausal osteoporosis	0.574	0.425	0.000
M79.67 Pain in limb (Ankle and foot)	0.574	0.426	0.000
J06.9 Acute upper respiratory infection, unspecified	0.574	0.426	0.000
S22.2 Fracture of sternum	0.574	0.426	0.000
S92 Fracture of foot, except ankle	0.573	0.427	0.000
M99 Biomechanical lesions, not elsewhere classified	0.573	0.427	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.573	0.427	0.000
L60-L75 Disorders of skin appendages	0.572	0.428	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.572	0.428	0.000
J38.6 Stenosis of larynx	0.572	0.428	0.000
J38.5 Laryngeal spasm	0.572	0.428	0.000
Q60-Q64 Congenital malformations of the urinary system	0.572	0.428	0.000
J31.0 Chronic rhinitis	0.572	0.428	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.571	0.429	0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.570	0.429	0.000
L95 Vasculitis limited to skin, not elsewhere classified	0.570	0.429	0.000
L94 Other localised connective tissue disorders	0.570	0.429	0.000
L93 Lupus erythematosus	0.570	0.429	0.000
L87 Transepidermal elimination disorders	0.570	0.429	0.000
L88 Pyoderma gangrenosum	0.570	0.429	0.000
L86 Keratoderma in diseases classified elsewhere	0.570	0.429	0.000
L83 Acanthosis nigricans	0.570	0.429	0.000
L80 Vitiligo	0.570	0.429	0.000
S40 Superficial injury of shoulder and upper arm	0.570	0.430	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.569	0.430	0.000
M00 Pyogenic arthritis	0.569	0.431	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.569	0.431	0.000
N10 Acute tubulo-interstitial nephritis	0.569	0.431	0.000
T81.8 Other complications of procedures, not elsewhere classified	0.568	0.432	0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.568	0.432	0.000
J04 Acute laryngitis and tracheitis	0.568	0.432	0.000
W06 Fall involving bed	0.567	0.432	0.000
J38.3 Other diseases of vocal cords	0.567	0.432	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.567	0.433	0.000
L85.8 Other specified epidermal thickening	0.567	0.433	0.000
M05.8 Other seropositive rheumatoid arthritis	0.567	0.433	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.567	0.433	0.000
M05.2 Rheumatoid vasculitis	0.567	0.433	0.000
M05.1 Rheumatoid lung disease	0.567	0.433	0.000
M05.0 Felty's syndrome	0.567	0.433	0.000
S22.3 Fracture of rib	0.567	0.433	0.000
L50 Urticaria	0.566	0.434	0.000
A00-A09 Intestinal infectious diseases	0.566	0.434	0.001
W13 Fall from, out of or through building or structure	0.566	0.434	0.000
M10 Gout	0.565	0.435	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.564	0.436	0.000
M49 Spondylopathies in diseases classified elsewhere	0.563	0.437	0.000
S52.0 Fracture of upper end of ulna	0.562	0.438	0.000
S72.4 Fracture of lower end of femur	0.562	0.438	0.000
T31 Burns classified according to extent of body surface involved	0.562	0.438	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.561	0.439	0.000
J43.8 Other emphysema	0.561	0.439	0.000
J43.2 Centrilobular emphysema	0.561	0.439	0.000
J43.1 Panlobular emphysema	0.561	0.439	0.000
J43.0 MacLeod's syndrome	0.561	0.439	0.000
Y40 Systemic antibiotics	0.561	0.439	0.000
Y44 Agents primarily affecting blood constituents	0.559	0.441	0.000
L89 Decubitus ulcer	0.559	0.441	0.000
M54.69 Pain in thoracic spine-Site unspe	0.558	0.441	0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.558	0.441	0.000
M54.67 Pain in thoracic spine-Lumbosacral	0.558	0.441	0.000
M54.66 Pain in thoracic spine-Lumbar	0.558	0.441	0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.558	0.441	0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.558	0.441	0.000
M54.62 Pain in thoracic spine-Cervical	0.558	0.441	0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.558	0.441	0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.558	0.441	0.000
J40 Bronchitis, not specified as acute or chronic	0.558	0.442	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.557	0.442	0.000
M84.0 Malunion of fracture	0.557	0.443	0.000
S59 Other and unspecified injuries of forearm	0.557	0.443	0.000
S58 Traumatic amputation of forearm	0.557	0.443	0.000
S57 Crushing injury of forearm	0.557	0.443	0.000
S56 Injury of muscle and tendon at forearm level	0.557	0.443	0.000
S55 Injury of blood vessels at forearm level	0.557	0.443	0.000
S54 Injury of nerves at forearm level	0.557	0.443	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.557	0.443	0.000
S50 Superficial injury of forearm	0.557	0.443	0.000
G25 Other extrapyramidal and movement disorders	0.556	0.444	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations