TreeWAS – Variant ID: rs16887812

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R19.5 Other fecal abnormalities	0.072	0.928	0.000
R73.9 Hyperglycaemia, unspecified	0.000	0.984	0.016
R73.0 Abnormal glucose tolerance test	0.000	0.986	0.014
R73 Elevated blood glucose level	0.000	0.986	0.014
G62.8 Other specified polyneuropathies	0.013	0.987	0.000
K22.4 Dyskinesia of oesophagus	0.000	0.987	0.013
K91.3 Postoperative intestinal obstruction	0.012	0.988	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.012	0.988	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.012	0.988	0.000
I33.0 Acute and subacute infective endocarditis	0.010	0.990	0.000
M89.9 Disorder of bone, unspecified	0.009	0.991	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.008	0.992	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.008	0.992	0.000
C16.0 Cardia	0.000	0.993	0.007
M89.92 Disorder of bone, unspecified (Upper arm)	0.007	0.993	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.007	0.993	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.007	0.993	0.000
M89.98 Disorder of bone, unspecified (Other)	0.007	0.993	0.000
O82.1 Delivery by emergency Caesarean section	0.000	0.993	0.007
M89.99 Disorder of bone, unspecified (Site unspecified)	0.007	0.993	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.006	0.994	0.000
G62 Other polyneuropathies	0.006	0.994	0.000
C16 Malignant neoplasm of stomach	0.000	0.994	0.006
C16.9 Stomach, unspecified	0.000	0.994	0.006
G62.0 Drug-induced polyneuropathy	0.005	0.994	0.000
H93.1 Tinnitus	0.000	0.995	0.005
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.005	0.995	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.005	0.995	0.000
I63.9 Cerebral infarction, unspecified	0.005	0.995	0.000
C16.3 Pyloric antrum	0.000	0.995	0.005
I63 Cerebral infarction	0.005	0.995	0.000
O82 Single delivery by Caesarean section	0.000	0.995	0.005
G62.1 Alcoholic polyneuropathy	0.005	0.995	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.995	0.005
C16.4 Pylorus	0.000	0.995	0.005
O82.0 Delivery by elective Caesarean section	0.000	0.995	0.005
C92.0 Acute myeloid leukaemia	0.005	0.995	0.000
G62.2 Polyneuropathy due to other toxic agents	0.004	0.995	0.000
C16.5 Lesser curvature of stomach, unspecified	0.000	0.995	0.005
C16.1 Fundus of stomach	0.000	0.995	0.004
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.004	0.995	0.000
I63.8 Other cerebral infarction	0.004	0.996	0.000
C16.8 Overlapping lesion of stomach	0.000	0.996	0.004
J33.0 Polyp of nasal cavity	0.000	0.996	0.004
R19 Other symptoms and signs involving the digestive system and abdomen	0.004	0.996	0.000
C92 Myeloid leukaemia	0.004	0.996	0.000
C16.2 Body of stomach	0.000	0.996	0.004
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.004	0.996	0.000
C92.4 Acute promyelocytic leukaemia	0.004	0.996	0.000
I33 Acute and subacute endocarditis	0.004	0.996	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.004	0.996	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.004	0.996	0.000
O82.8 Other single delivery by Caesarean section	0.000	0.996	0.004
O82.2 Delivery by Caesarean hysterectomy	0.000	0.996	0.004
T79.8 Other early complications of trauma	0.004	0.996	0.000
O82.9 Delivery by Caesarean section, unspecified	0.000	0.996	0.004
T79.3 Post-traumatic wound infection, not elsewhere classified	0.004	0.996	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.000	0.996	0.004
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.004	0.996	0.000
S92.30 Fracture of metatarsal bone (closed)	0.000	0.996	0.004
C92.9 Myeloid leukaemia, unspecified	0.004	0.996	0.000
C16.6 Greater curvature of stomach, unspecified	0.000	0.996	0.004
K07.3 Anomalies of tooth position	0.004	0.996	0.000
K86.8 Other specified diseases of pancreas	0.000	0.996	0.004
M89 Other disorders of bone	0.004	0.996	0.000
J34.8 Other specified disorders of nose and nasal sinuses	0.004	0.996	0.000
M89.84 Other specified disorders of bone (Hand)	0.004	0.996	0.000
C92.1 Chronic myeloid leukaemia	0.004	0.996	0.000
M89.8 Other specified disorders of bone	0.004	0.996	0.000
R19.6 Halitosis	0.004	0.996	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.004	0.996	0.000
C92.7 Other myeloid leukaemia	0.003	0.996	0.000
R74 Abnormal serum enzyme levels	0.000	0.996	0.004
N99.4 Postprocedural pelvic peritoneal adhesions	0.000	0.996	0.004
H74.4 Polyp of middle ear	0.004	0.996	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.003	0.996	0.000
C92.5 Acute myelomonocytic leukaemia	0.003	0.997	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.003	0.997	0.000
R78 Findings of drugs and other substances, not normally found in blood	0.000	0.997	0.003
N42.9 Disorder of prostate, unspecified	0.003	0.997	0.000
R19.3 Abdominal rigidity	0.003	0.997	0.000
R19.1 Abnormal bowel sounds	0.003	0.997	0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.003	0.997	0.000
R76 Other abnormal immunological findings in serum	0.000	0.997	0.003
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.003	0.997	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.003	0.997	0.000
C92.3 Myeloid sarcoma	0.003	0.997	0.000
C92.2 Subacute myeloid leukaemia	0.003	0.997	0.000
R74.8 Abnormal levels of other serum enzymes	0.000	0.997	0.003
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.000	0.997	0.003
R77 Other abnormalities of plasma proteins	0.000	0.997	0.003
R76.8 Other specified abnormal immunological findings in serum	0.000	0.997	0.003
R78.0 Finding of alcohol in blood	0.000	0.997	0.003
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.997	0.003
R19.2 Visible peristalsis	0.003	0.997	0.000
R77.8 Other specified abnormalities of plasma proteins	0.000	0.997	0.003
S92.3 Fracture of metatarsal bone	0.000	0.997	0.003
Y86 Sequelae of other accidents	0.003	0.997	0.000
T79.5 Traumatic anuria	0.003	0.997	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.003	0.997	0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.000	0.997	0.003
M89.6 Osteopathy after poliomyelitis	0.003	0.997	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.003	0.997	0.000
M89.2 Other disorders of bone development and growth	0.003	0.997	0.000
M89.1 Epiphyseal arrest	0.003	0.997	0.000
M89.83 Other specified disorders of bone (Forearm)	0.003	0.997	0.000
I33.9 Acute endocarditis, unspecified	0.003	0.997	0.000
T79.7 Traumatic subcutaneous emphysema	0.003	0.997	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.003	0.997	0.000
K86.1 Other chronic pancreatitis	0.000	0.997	0.003
M89.82 Other specified disorders of bone (Upper arm)	0.003	0.997	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.003	0.997	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.003	0.997	0.000
S92.2 Fracture of other tarsal bone(s)	0.000	0.997	0.003
T79.9 Unspecified early complication of trauma	0.003	0.997	0.000
T79.4 Traumatic shock	0.003	0.997	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.003	0.997	0.000
T79.1 Fat embolism (traumatic)	0.003	0.997	0.000
T79.0 Air embolism (traumatic)	0.003	0.997	0.000
R78.8 Finding of other specified substances, not normally found in blood	0.000	0.997	0.003
R78.9 Finding of unspecified substance, not normally found in blood	0.000	0.997	0.003
R78.7 Finding of abnormal level of heavy metals in blood	0.000	0.997	0.003
R78.6 Finding of steroid agent in blood	0.000	0.997	0.003
R78.5 Finding of psychotropic drug in blood	0.000	0.997	0.003
R78.4 Finding of other drugs of addictive potential in blood	0.000	0.997	0.003
R78.3 Finding of hallucinogen in blood	0.000	0.997	0.003
R78.2 Finding of cocaine in blood	0.000	0.997	0.003
R78.1 Finding of opiate drug in blood	0.000	0.997	0.003
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.003	0.997	0.000
H66.9 Otitis media, unspecified	0.003	0.997	0.000
S90.8 Other superficial injuries of ankle and foot	0.000	0.997	0.003
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.000	0.997	0.003
R76.9 Abnormal immunological finding in serum, unspecified	0.000	0.997	0.003
R76.2 False-positive serological test for syphilis	0.000	0.997	0.003
R76.1 Abnormal reaction to tuberculin test	0.000	0.997	0.003
S92.40 Fracture of great toe (closed)	0.000	0.997	0.003
E27.1 Primary adrenocortical insufficiency	0.003	0.997	0.000
S92.4 Fracture of great toe	0.000	0.997	0.003
S92 Fracture of foot, except ankle	0.000	0.997	0.003
M89.81 Other specified disorders of bone (Shoulder region)	0.002	0.997	0.000
R77.1 Abnormality of globulin	0.000	0.997	0.002
E27.2 Addisonian crisis	0.003	0.997	0.000
M89.3 Hypertrophy of bone	0.002	0.997	0.000
R77.2 Abnormality of alphafetoprotein	0.000	0.997	0.002
T79.6 Traumatic ischaemia of muscle	0.002	0.997	0.000
R74.9 Abnormal level of unspecified serum enzyme	0.000	0.997	0.002
H74 Other disorders of middle ear and mastoid	0.003	0.997	0.000
S92.31 Fracture of metatarsal bone (open)	0.000	0.997	0.002
M89.5 Osteolysis	0.002	0.997	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.002	0.997	0.000
G60 Hereditary and idiopathic neuropathy	0.002	0.997	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
E27 Other disorders of adrenal gland	0.002	0.998	0.000
H73.8 Other specified disorders of tympanic membrane	0.002	0.998	0.000
H73 Other disorders of tympanic membrane	0.002	0.998	0.000
S92.5 Fracture of other toe	0.000	0.998	0.002
M89.19 Epiphyseal arrest (Site unspecified)	0.002	0.998	0.000
M89.18 Epiphyseal arrest (Other)	0.002	0.998	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.002	0.998	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.002	0.998	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.002	0.998	0.000
M89.14 Epiphyseal arrest (Hand)	0.002	0.998	0.000
M89.13 Epiphyseal arrest (Forearm)	0.002	0.998	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.002	0.998	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.002	0.998	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.002	0.998	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.002	0.998	0.000
M89.28 Other disorders of bone development and growth (Other)	0.002	0.998	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.002	0.998	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.002	0.998	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.002	0.998	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.002	0.998	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.002	0.998	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.002	0.998	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.002	0.998	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.002	0.998	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.002	0.998	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.002	0.998	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.002	0.998	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.002	0.998	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.002	0.998	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.002	0.998	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.002	0.998	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.002	0.998	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.002	0.998	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.002	0.998	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.002	0.998	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.002	0.998	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.002	0.998	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.002	0.998	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.002	0.998	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.002	0.998	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.002	0.998	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.002	0.998	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.002	0.998	0.000
M89.88 Other specified disorders of bone (Other)	0.002	0.998	0.000
S92.51 Fracture of other toe (open)	0.000	0.998	0.002
R76.0 Raised antibody titer	0.000	0.998	0.002
R77.9 Abnormality of plasma protein, unspecified	0.000	0.998	0.002
M89.0 Algoneurodystrophy	0.002	0.998	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.000	0.998	0.002
G60.0 Hereditary motor and sensory neuropathy	0.002	0.998	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.002	0.998	0.000
S92.41 Fracture of great toe (open)	0.000	0.998	0.002
E27.9 Disorder of adrenal gland, unspecified	0.002	0.998	0.000
R71 Abnormality of red blood cells	0.000	0.998	0.002
H73.9 Disorder of tympanic membrane, unspecified	0.002	0.998	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.002	0.998	0.000
R77.0 Abnormality of albumin	0.000	0.998	0.002
C26.0 Intestinal tract, part unspecified	0.000	0.998	0.002
G64 Other disorders of peripheral nervous system	0.002	0.998	0.000
H66.4 Suppurative otitis media, unspecified	0.002	0.998	0.000
H66 Suppurative and unspecified otitis media	0.002	0.998	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.002	0.998	0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.002	0.998	0.000
S92.1 Fracture of talus	0.000	0.998	0.002
G60.8 Other hereditary and idiopathic neuropathies	0.002	0.998	0.000
H70 Mastoiditis and related conditions	0.002	0.998	0.000
M89.39 Hypertrophy of bone (Site unspecified)	0.002	0.998	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.002	0.998	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.002	0.998	0.000
M89.34 Hypertrophy of bone (Hand)	0.002	0.998	0.000
M89.33 Hypertrophy of bone (Forearm)	0.002	0.998	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.002	0.998	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.002	0.998	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.002	0.998	0.000
C26.9 Ill-defined sites within the digestive system	0.000	0.998	0.002
H53.4 Visual field defects	0.002	0.998	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.998	0.002
H65-H75 Diseases of middle ear and mastoid	0.002	0.998	0.000
W02.9 Unspecified place	0.000	0.998	0.002
R70.1 Abnormal plasma viscosity	0.000	0.998	0.002
H70.9 Mastoiditis, unspecified	0.002	0.998	0.000
M89.59 Osteolysis (Site unspecified)	0.002	0.998	0.000
M89.58 Osteolysis (Other)	0.002	0.998	0.000
M89.57 Osteolysis (Ankle and foot)	0.002	0.998	0.000
M89.56 Osteolysis (Lower leg)	0.002	0.998	0.000
M89.54 Osteolysis (Hand)	0.002	0.998	0.000
M89.53 Osteolysis (Forearm)	0.002	0.998	0.000
M89.52 Osteolysis (Upper arm)	0.002	0.998	0.000
M89.51 Osteolysis (Shoulder region)	0.002	0.998	0.000
M89.50 Osteolysis (Multiple sites)	0.002	0.998	0.000
H73.1 Chronic myringitis	0.002	0.998	0.000
M89.38 Hypertrophy of bone (Other)	0.002	0.998	0.000
E27.5 Adrenomedullary hyperfunction	0.002	0.998	0.000
E27.0 Other adrenocortical overactivity	0.002	0.998	0.000
G60.3 Idiopathic progressive neuropathy	0.002	0.998	0.000
G60.2 Neuropathy in association with hereditary ataxia	0.002	0.998	0.000
G60.1 Refsum's disease	0.002	0.998	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.002	0.998	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.002	0.998	0.000
S06.00 Concussion (without open intracranial wound)	0.000	0.998	0.002
G62.9 Polyneuropathy, unspecified	0.000	0.998	0.002
H73.0 Acute myringitis	0.002	0.998	0.000
R70.0 Elevated erythrocyte sedimentation rate	0.000	0.998	0.002
H69 Other disorders of Eustachian tube	0.002	0.998	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.002	0.998	0.000
H70.8 Other mastoiditis and related conditions	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.000	0.998	0.002
K86 Other diseases of pancreas	0.000	0.998	0.002
R72 Abnormality of white blood cells, not elsewhere classified	0.000	0.998	0.002
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.002	0.998	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.002	0.998	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.002	0.998	0.000
S92.9 Fracture of foot, unspecified	0.000	0.998	0.002
M89.08 Algoneurodystrophy (Other)	0.002	0.998	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.002	0.998	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.002	0.998	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.002	0.998	0.000
S64.3 Injury of digital nerve of thumb	0.002	0.998	0.000
H68 Eustachian salpingitis and obstruction	0.002	0.998	0.000
M89.04 Algoneurodystrophy (Hand)	0.002	0.998	0.000
M89.03 Algoneurodystrophy (Forearm)	0.002	0.998	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.002	0.998	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.998	0.002
C26 Malignant neoplasm of other and ill-defined digestive organs	0.000	0.998	0.002
S92.50 Fracture of other toe (closed)	0.000	0.998	0.002
H74.1 Adhesive middle ear disease	0.002	0.998	0.000
H65.0 Acute serous otitis media	0.002	0.998	0.000
H74.0 Tympanosclerosis	0.002	0.998	0.000
S92.11 Fracture of talus (open)	0.000	0.998	0.002
H68.1 Obstruction of Eustachian tube	0.002	0.998	0.000
H70.2 Petrositis	0.002	0.998	0.000
H70.0 Acute mastoiditis	0.002	0.998	0.000
S92.10 Fracture of talus (closed)	0.000	0.998	0.002
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.998	0.002
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.998	0.002
E16.4 Abnormal secretion of gastrin	0.000	0.998	0.002
E16.3 Increased secretion of glucagon	0.000	0.998	0.002
H69.9 Eustachian tube disorder, unspecified	0.002	0.998	0.000
K86.9 Disease of pancreas, unspecified	0.000	0.998	0.002
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.002	0.998	0.000
H67 Otitis media in diseases classified elsewhere	0.002	0.998	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.002	0.998	0.000
H69.8 Other specified disorders of Eustachian tube	0.002	0.998	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.002	0.998	0.000
H65 Nonsuppurative otitis media	0.002	0.998	0.000
N48.8 Other specified disorders of penis	0.000	0.998	0.002
Z74.2 Need for assistance at home and no other household member able to render care	0.000	0.998	0.002
H70.1 Chronic mastoiditis	0.002	0.998	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.998	0.002
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.002	0.998	0.000
I38 Endocarditis, valve unspecified	0.002	0.998	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.001	0.998	0.000
H69.0 Patulous Eustachian tube	0.002	0.998	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.002	0.998	0.000
S92.71 Multiple fractures of foot (open)	0.000	0.998	0.001
J94.8 Other specified pleural conditions	0.002	0.998	0.000
S92.91 Fracture of foot, unspecified (open)	0.000	0.998	0.001
H68.0 Eustachian salpingitis	0.001	0.998	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.998	0.002
C65 Malignant neoplasm of renal pelvis	0.000	0.998	0.002
M89.55 Osteolysis (Pelvic region and thigh)	0.001	0.998	0.001
C26.8 Overlapping lesion of digestive system	0.000	0.998	0.001
C26.1 Spleen	0.000	0.998	0.001
E16.1 Other hypoglycaemia	0.000	0.998	0.001
Z50.2 Alcohol rehabilitation	0.000	0.998	0.002
M21.24 Flexion deformity (Hand)	0.000	0.998	0.002
H66.2 Chronic atticoantral suppurative otitis media	0.001	0.998	0.000
H66.0 Acute suppurative otitis media	0.001	0.998	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.001	0.998	0.000
I65.2 Occlusion and stenosis of carotid artery	0.002	0.998	0.000
C15.5 Lower third of oesophagus	0.002	0.998	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.002	0.998	0.000
H65.3 Chronic mucoid otitis media	0.002	0.998	0.000
E65 Localised adiposity	0.000	0.998	0.002
M89.06 Algoneurodystrophy (Lower leg)	0.001	0.998	0.001
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.998	0.002
H67.8 Otitis media in other diseases classified elsewhere	0.001	0.998	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.001	0.998	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.001	0.998	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.001	0.998	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
J94.2 Haemothorax	0.002	0.998	0.000
S92.0 Fracture of calcaneus	0.000	0.998	0.001
M24.07 Loose body in joint (Ankle and foot)	0.000	0.998	0.001
M79.61 Pain in limb (Shoulder region)	0.002	0.998	0.000
D22.5 Melanocytic naevi of trunk	0.002	0.998	0.000
K00.6 Disturbances in tooth eruption	0.000	0.998	0.002
T79-T79 Certain early complications of trauma	0.002	0.998	0.000
H65.1 Other acute nonsuppurative otitis media	0.001	0.998	0.000
J39.2 Other diseases of pharynx	0.002	0.998	0.000
K07.6 Temporomandibular joint disorders	0.000	0.998	0.001
K91.4 Colostomy and enterostomy malfunction	0.002	0.998	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.998	0.002
S92.70 Multiple fractures of foot (closed)	0.000	0.998	0.001
S92.90 Fracture of foot, unspecified (closed)	0.000	0.998	0.001
G63.8 Polyneuropathy in other diseases classified elsewhere	0.001	0.998	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.001	0.998	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.001	0.998	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.001	0.998	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.001	0.998	0.000
G63.1 Polyneuropathy in neoplastic disease	0.001	0.998	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
J15.1 Pneumonia due to Pseudomonas	0.002	0.998	0.000
J15.0 Pneumonia due to Klebsiella pneumoniae	0.002	0.998	0.000
S90 Superficial injury of ankle and foot	0.000	0.998	0.002
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.998	0.001
K91.1 Postgastric surgery syndromes	0.001	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.000	0.998	0.001
E27.8 Other specified disorders of adrenal gland	0.001	0.998	0.000
K91.5 Postcholecystectomy syndrome	0.001	0.999	0.000
M66.2 Spontaneous rupture of extensor tendons	0.001	0.999	0.000
I65.1 Occlusion and stenosis of basilar artery	0.001	0.999	0.000
T86.1 Kidney transplant failure and rejection	0.001	0.999	0.000
K07.4 Malocclusion, unspecified	0.001	0.999	0.000
Y44.2 Anticoagulants	0.001	0.999	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.999	0.001
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.001	0.999	0.000
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.001	0.999	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.001	0.999	0.000
S29.9 Unspecified injury of thorax	0.000	0.999	0.001
S92.01 Fracture of calcaneus (open)	0.000	0.999	0.001
E06.3 Autoimmune thyroiditis	0.001	0.999	0.000
I47.0 Reentry ventricular arrhythmia	0.001	0.999	0.000
O80-O84 Delivery	0.000	0.999	0.001
N90.5 Atrophy of vulva	0.000	0.999	0.001
O20.0 Threatened abortion	0.001	0.999	0.000
S19.9 Unspecified injury of neck	0.000	0.999	0.001
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.001	0.999	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.000	0.999	0.001
S90.2 Contusion of toe(s) with damage to nail	0.000	0.999	0.001
Y83.5 Amputation of limb(s)	0.000	0.999	0.001
S90.1 Contusion of toe(s) without damage to nail	0.000	0.999	0.001
Z89.5 Acquired absence of leg at or below knee	0.001	0.999	0.000
T68 Hypothermia	0.000	0.999	0.001
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.999	0.000
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.001	0.999	0.000
M66.28 Spontaneous rupture of extensor tendons-Other	0.001	0.999	0.000
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.001	0.999	0.000
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.001	0.999	0.000
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.001	0.999	0.000
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.001	0.999	0.000
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.001	0.999	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.001	0.999	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.001	0.999	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.999	0.001
L29.0 Pruritus ani	0.000	0.999	0.001
M21.27 Flexion deformity (Ankle and foot)	0.000	0.999	0.001
M21.26 Flexion deformity (Lower leg)	0.000	0.999	0.001
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.001	0.999	0.000
M76.66 Achilles tendinitis (Lower leg)	0.000	0.999	0.001
G61.9 Inflammatory polyneuropathy, unspecified	0.001	0.999	0.000
J93.8 Other pneumothorax	0.000	0.999	0.001
R16.0 Hepatomegaly, not elsewhere classified	0.001	0.999	0.000
G61 Inflammatory polyneuropathy	0.001	0.999	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.999	0.001
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.999	0.001
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
C67.0 Trigone of bladder	0.000	0.999	0.001
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.001	0.999	0.000
I62.1 Nontraumatic extradural haemorrhage	0.001	0.999	0.000
J94 Other pleural conditions	0.001	0.999	0.000
O84 Multiple delivery	0.000	0.999	0.001
O83 Other assisted single delivery	0.000	0.999	0.001
H65.4 Other chronic nonsuppurative otitis media	0.001	0.999	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.001	0.999	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.001	0.999	0.000
H93 Other disorders of ear, not elsewhere classified	0.000	0.999	0.001
O81 Single delivery by forceps and vacuum extractor	0.000	0.999	0.001
M25.47 Effusion of joint (Ankle and foot)	0.000	0.999	0.001
M60.99 Myositis, unspecified (Site unspecified)	0.001	0.999	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.001	0.999	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.001	0.999	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M79.64 Pain in limb (Hand)	0.001	0.999	0.000
A08.4 Viral intestinal infection, unspecified	0.000	0.999	0.001
I65.8 Occlusion and stenosis of other precerebral artery	0.001	0.999	0.000
J94.1 Fibrothorax	0.001	0.999	0.000
G61.1 Serum neuropathy	0.001	0.999	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.000	0.999	0.001
K91.9 Postprocedural disorder of digestive system, unspecified	0.001	0.999	0.000
M21.2 Flexion deformity	0.000	0.999	0.001
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.000	0.999	0.001
O36.5 Maternal care for poor foetal growth	0.001	0.999	0.000
S90.0 Contusion of ankle	0.000	0.999	0.001
I62 Other nontraumatic intracranial haemorrhage	0.001	0.999	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.001	0.999	0.000
M66.45 Spontaneous rupture of other tendons (Pelvic region and thigh)	0.001	0.999	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.001	0.999	0.000
J15.2 Pneumonia due to staphylococcus	0.001	0.999	0.000
J94.9 Pleural condition, unspecified	0.001	0.999	0.000
J94.0 Chylous effusion	0.001	0.999	0.000
O81.4 Vacuum extractor delivery	0.000	0.999	0.001
O81.0 Low forceps delivery	0.000	0.999	0.001
O83.9 Assisted single delivery, unspecified	0.000	0.999	0.001
O83.8 Other specified assisted single delivery	0.000	0.999	0.001
O83.4 Destructive operation for delivery	0.000	0.999	0.001
O83.3 Delivery of viable foetus in abdominal pregnancy	0.000	0.999	0.001
O83.2 Other manipulation-assisted delivery	0.000	0.999	0.001
O83.1 Other assisted breech delivery	0.000	0.999	0.001
O83.0 Breech extraction	0.000	0.999	0.001
O84.9 Multiple delivery, unspecified	0.000	0.999	0.001
O84.8 Other multiple delivery	0.000	0.999	0.001
O84.2 Multiple delivery, all by Caesarean section	0.000	0.999	0.001
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.000	0.999	0.001
O84.0 Multiple delivery, all spontaneous	0.000	0.999	0.001
J15 Bacterial pneumonia, not elsewhere classified	0.001	0.999	0.000
M13.94 Arthritis, unspecified (Hand)	0.001	0.999	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.001	0.999	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
H93.2 Other abnormal auditory perceptions	0.000	0.999	0.001
H93.0 Degenerative and vascular disorders of ear	0.000	0.999	0.001
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.001	0.999	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.001	0.999	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.999	0.001
O81.5 Delivery by combination of forceps and vacuum extractor	0.000	0.999	0.001
O81.2 Mid-cavity forceps with rotation	0.000	0.999	0.001
O81.1 Mid-cavity forceps delivery	0.000	0.999	0.001
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.999	0.001
G24.9 Dystonia, unspecified	0.000	0.999	0.001
H65.2 Chronic serous otitis media	0.001	0.999	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.001	0.999	0.000
J98.9 Respiratory disorder, unspecified	0.000	0.999	0.001
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.999	0.001
I60-I69 Cerebrovascular diseases	0.001	0.999	0.000
M21.29 Flexion deformity (Site unspecified)	0.000	0.999	0.001
M21.28 Flexion deformity (Other)	0.000	0.999	0.001
M21.25 Flexion deformity (Pelvic region and thigh)	0.000	0.999	0.001
M21.23 Flexion deformity (Forearm)	0.000	0.999	0.001
M21.22 Flexion deformity (Upper arm)	0.000	0.999	0.001
M21.21 Flexion deformity (Shoulder region)	0.000	0.999	0.001
M21.20 Flexion deformity (Multiple sites)	0.000	0.999	0.001
I61.6 Intracerebral haemorrhage, multiple localised	0.001	0.999	0.000
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.001	0.999	0.000
J01.9 Acute sinusitis, unspecified	0.001	0.999	0.000
J15.3 Pneumonia due to streptococcus, group B	0.001	0.999	0.000
K05.3 Chronic periodontitis	0.001	0.999	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.999	0.001
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.999	0.001
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.999	0.001
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.999	0.001
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.001	0.999	0.000
M76.67 Achilles tendinitis (Ankle and foot)	0.000	0.999	0.001
M87.24 Osteonecrosis due to previous trauma (Hand)	0.001	0.999	0.000
C22.0 Liver cell carcinoma	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations