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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16891867
log Bayes Factor = 9.13304
Chromosome 4   position 15,397,364  (GRCh37) Explore rs16891867 on Ensembl!
Variant rs16891867 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
I60-I69 Cerebrovascular diseases
0.997 0.003 0.000
Chapter V Mental and behavioural disorders
0.994 0.006 0.000
Chapter XX External causes of morbidity and mortality
0.992 0.008 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.980 0.020 0.000
S40-S49 Injuries to the shoulder and upper arm
0.978 0.022 0.000
Chapter I Certain infectious and parasitic diseases
0.976 0.024 0.000
H53-H54 Visual disturbances and blindness
0.975 0.025 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.974 0.026 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.970 0.030 0.000
F10.3 Withdrawal state
0.963 0.037 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.961 0.039 0.000
H53 Visual disturbances
0.959 0.041 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.959 0.041 0.000
I30-I52 Other forms of heart disease
0.954 0.046 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.950 0.050 0.000
H53.9 Visual disturbance, unspecified
0.938 0.062 0.000
B35-B49 Mycoses
0.933 0.067 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.933 0.067 0.000
Chapter X Diseases of the respiratory system
0.930 0.070 0.000
I69 Sequelae of cerebrovascular disease
0.929 0.071 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.926 0.074 0.000
H30-H36 Disorders of choroid and retina
0.920 0.080 0.000
I61 Intracerebral haemorrhage
0.919 0.081 0.000
I71 Aortic aneurysm and dissection
0.915 0.085 0.000
I67 Other cerebrovascular diseases
0.913 0.087 0.000
I05-I09 Chronic rheumatic heart diseases
0.910 0.090 0.000
H53.2 Diplopia
0.903 0.097 0.000
S20-S29 Injuries to the thorax
0.903 0.097 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.900 0.100 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.898 0.102 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.889 0.111 0.000
Y43 Primarily systemic agents
0.887 0.113 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.882 0.118 0.000
I51 Complications and ill-defined descriptions of heart disease
0.880 0.120 0.000
Y52 Agents primarily affecting the cardiovascular system
0.878 0.122 0.000
S50-S59 Injuries to the elbow and forearm
0.872 0.128 0.000
I63 Cerebral infarction
0.870 0.130 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.870 0.130 0.000
I62 Other nontraumatic intracranial haemorrhage
0.868 0.131 0.000
I74 Arterial embolism and thrombosis
0.869 0.131 0.000
B37 Candidiasis
0.865 0.135 0.000
J95-J99 Other diseases of the respiratory system
0.863 0.137 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.856 0.144 0.000
I67.9 Cerebrovascular disease, unspecified
0.854 0.146 0.000
I47 Paroxysmal tachycardia
0.854 0.146 0.000
I50 Heart failure
0.854 0.146 0.000
F30-F39 Mood [affective] disorders
0.853 0.147 0.000
S42 Fracture of shoulder and upper arm
0.851 0.149 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.849 0.151 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.846 0.154 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.841 0.159 0.000
M20-M25 Other joint disorders
0.840 0.160 0.000
M25 Other joint disorders, not elsewhere classified
0.840 0.160 0.000
X60-X84 Intentional self-harm
0.839 0.161 0.000
M25.5 Pain in joint
0.837 0.163 0.000
D75 Other diseases of blood and blood-forming organs
0.836 0.164 0.000
B37.9 Candidiasis, unspecified
0.834 0.166 0.000
J81 Pulmonary oedema
0.834 0.166 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.833 0.166 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.833 0.167 0.000
V40-V49 Car occupant injured in transport accident
0.831 0.169 0.000
I05 Rheumatic mitral valve diseases
0.830 0.170 0.000
Y43.3 Other antineoplastic drugs
0.829 0.171 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.824 0.176 0.000
H04 Disorders of lachrymal system
0.824 0.176 0.000
I95 Hypotension
0.822 0.178 0.000
I35 Nonrheumatic aortic valve disorders
0.814 0.186 0.000
S90-S99 Injuries to the ankle and foot
0.813 0.187 0.000
T91 Sequelae of injuries of neck and trunk
0.812 0.188 0.000
S10-S19 Injuries to the neck
0.811 0.189 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.809 0.191 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.806 0.194 0.000
H18 Other disorders of cornea
0.804 0.196 0.000
I34 Nonrheumatic mitral valve disorders
0.803 0.197 0.000
S51 Open wound of forearm
0.803 0.197 0.000
O60-O75 Complications of labour and delivery
0.803 0.197 0.000
E70-E90 Metabolic disorders
0.802 0.198 0.000
I51.7 Cardiomegaly
0.801 0.199 0.000
A30-A49 Other bacterial diseases
0.800 0.200 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.799 0.201 0.000
B49 Unspecified mycosis
0.799 0.201 0.000
E00-E07 Disorders of thyroid gland
0.799 0.201 0.000
F10.0 Acute intoxication
0.799 0.201 0.000
H16 Keratitis
0.799 0.201 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.798 0.202 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.798 0.202 0.000
I47.2 Ventricular tachycardia
0.797 0.203 0.000
B25-B34 Other viral diseases
0.795 0.205 0.000
J90-J94 Other diseases of pleura
0.795 0.205 0.000
W00-W19 Falls
0.792 0.208 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.790 0.210 0.000
E65-E68 Obesity and other hyperalimentation
0.786 0.214 0.000
H35 Other retinal disorders
0.786 0.214 0.000
S70-S79 Injuries to the hip and thigh
0.785 0.215 0.000
F99-F99 Unspecified mental disorder
0.785 0.215 0.000
T93 Sequelae of injuries of lower limb
0.785 0.215 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.784 0.216 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.783 0.216 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.781 0.219 0.000
T92 Sequelae of injuries of upper limb
0.780 0.220 0.000
F60-F69 Disorders of adult personality and behaviour
0.780 0.220 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.779 0.221 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.778 0.222 0.000
M25.57 Pain in joint (Ankle and foot)
0.778 0.222 0.000
T98 Sequelae of other and unspecified effects of external causes
0.777 0.223 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.776 0.224 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.774 0.226 0.000
S42.0 Fracture of clavicle
0.772 0.228 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.772 0.228 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.771 0.229 0.000
S41 Open wound of shoulder and upper arm
0.770 0.230 0.000
I63.9 Cerebral infarction, unspecified
0.770 0.230 0.000
B95-B98 Bacterial, viral and other infectious agents
0.769 0.231 0.000
D72 Other disorders of white blood cells
0.769 0.231 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.769 0.231 0.000
Chapter VIII Diseases of the ear and mastoid process
0.769 0.231 0.000
S43.0 Dislocation of shoulder joint
0.769 0.231 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.768 0.232 0.000
A80-A89 Viral infections of the central nervous system
0.766 0.233 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.765 0.235 0.000
H31 Other disorders of choroid
0.764 0.236 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.762 0.238 0.000
T66-T78 Other and unspecified effects of external causes
0.762 0.238 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.760 0.240 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.759 0.241 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.757 0.243 0.000
W50-W64 Exposure to animate mechanical forces
0.757 0.243 0.000
F10.2 Dependence syndrome
0.756 0.244 0.000
J30-J39 Other diseases of upper respiratory tract
0.756 0.244 0.000
I35.1 Aortic (valve) insufficiency
0.754 0.245 0.000
S32 Fracture of lumbar spine and pelvis
0.754 0.246 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.754 0.246 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.753 0.247 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.753 0.247 0.000
I67.2 Cerebral atherosclerosis
0.752 0.248 0.000
J98 Other respiratory disorders
0.751 0.249 0.000
D80-D89 Certain disorders involving the immune mechanism
0.750 0.250 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.750 0.250 0.000
B99-B99 Other infectious diseases
0.750 0.250 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.749 0.250 0.000
T90 Sequelae of injuries of head
0.749 0.251 0.000
M25.53 Pain in joint (Forearm)
0.749 0.251 0.000
H04.2 Epiphora
0.748 0.252 0.000
S20 Superficial injury of thorax
0.748 0.252 0.000
I95.1 Orthostatic hypotension
0.747 0.253 0.000
D75.1 Secondary polycythaemia
0.746 0.254 0.000
F11 Mental and behavioural disorders due to use of opioids
0.745 0.255 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.745 0.255 0.000
E10-E14 Diabetes mellitus
0.743 0.257 0.000
E40-E46 Malnutrition
0.742 0.258 0.000
H10-H13 Disorders of conjunctiva
0.737 0.262 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.737 0.263 0.000
V10-V19 Pedal cyclist injured in transport accident
0.736 0.264 0.000
I31 Other diseases of pericardium
0.736 0.264 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.734 0.266 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.733 0.267 0.000
S21 Open wound of thorax
0.727 0.273 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.725 0.275 0.000
E20-E35 Disorders of other endocrine glands
0.724 0.276 0.000
H33 Retinal detachments and breaks
0.724 0.276 0.000
J84 Other interstitial pulmonary diseases
0.723 0.277 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.723 0.277 0.000
M86-M90 Other osteopathies
0.722 0.278 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.722 0.278 0.000
I51.6 Cardiovascular disease, unspecified
0.720 0.280 0.000
I78 Diseases of capillaries
0.720 0.280 0.000
Y57 Other and unspecified drugs and medicaments
0.719 0.281 0.000
E06 Thyroiditis
0.719 0.281 0.000
F80-F89 Disorders of psychological development
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S42.00 Fracture of clavicle (closed)
0.715 0.285 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.715 0.285 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.715 0.285 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.714 0.286 0.000
I37 Pulmonary valve disorders
0.714 0.286 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.713 0.287 0.000
I05.9 Mitral valve disease, unspecified
0.713 0.287 0.000
I70 Atherosclerosis
0.712 0.287 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.712 0.287 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.712 0.288 0.000
F70-F79 Mental retardation
0.712 0.288 0.000
H53.4 Visual field defects
0.712 0.288 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.711 0.289 0.000
Y10-Y34 Event of undetermined intent
0.711 0.289 0.000
Y00-Y09 Assault
0.711 0.289 0.000
X85-X99 Assault
0.711 0.289 0.000
X50-X57 Overexertion, travel and privation
0.711 0.289 0.000
X30-X39 Exposure to forces of nature
0.711 0.289 0.000
X20-X29 Contact with venomous animals and plants
0.711 0.289 0.000
X10-X19 Contact with heat and hot substances
0.711 0.289 0.000
X00-X09 Exposure to smoke, fire and flames
0.711 0.289 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.711 0.289 0.000
W75-W84 Other accidental threats to breathing
0.711 0.289 0.000
W65-W74 Accidental drowning and submersion
0.711 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.711 0.289 0.000
V95-V97 Air and space transport accidents
0.711 0.289 0.000
V90-V94 Water transport accidents
0.711 0.289 0.000
V70-V79 Bus occupant injured in transport accident
0.711 0.289 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.711 0.289 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.711 0.289 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.711 0.289 0.000
V01-V09 Pedestrian injured in transport accident
0.711 0.289 0.000
W20-W49 Exposure to inanimate mechanical forces
0.710 0.290 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.709 0.291 0.000
V48 Car occupant injured in noncollision transport accident
0.709 0.291 0.000
B44 Aspergillosis
0.708 0.292 0.000
H16.0 Corneal ulcer
0.707 0.292 0.000
I50.9 Heart failure, unspecified
0.707 0.293 0.000
I08 Multiple valve diseases
0.705 0.295 0.000
S40 Superficial injury of shoulder and upper arm
0.704 0.296 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.703 0.297 0.000
F10.4 Withdrawal state with delirium
0.703 0.297 0.000
D55-D59 Haemolytic anaemias
0.703 0.297 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.703 0.297 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.703 0.297 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.703 0.297 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.703 0.297 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.703 0.297 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.703 0.297 0.000
D60-D64 Aplastic and other anaemias
0.702 0.298 0.000
S48 Traumatic amputation of shoulder and upper arm
0.701 0.299 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.701 0.299 0.000
S44 Injury of nerves at shoulder and upper arm level
0.701 0.299 0.000
S47 Crushing injury of shoulder and upper arm
0.701 0.299 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.700 0.300 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.700 0.300 0.000
B65-B83 Helminthiases
0.700 0.300 0.000
B50-B64 Protozoal diseases
0.700 0.300 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.700 0.300 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.700 0.300 0.000
A75-A79 Rickettsioses
0.700 0.300 0.000
A70-A74 Other diseases caused by chlamydiae
0.700 0.300 0.000
A65-A69 Other spirochaetal diseases
0.700 0.300 0.000
A20-A28 Certain zoonotic bacterial diseases
0.700 0.300 0.000
A15-A19 Tuberculosis
0.700 0.300 0.000
I05.0 Mitral stenosis
0.700 0.300 0.000
I60 Subarachnoid haemorrhage
0.699 0.301 0.000
Y59 Other and unspecified vaccines and biological substances
0.698 0.302 0.000
Y58 Bacterial vaccines
0.698 0.302 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.698 0.302 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.698 0.302 0.000
Y48 Anaesthetics and therapeutic gases
0.698 0.302 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.698 0.302 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.698 0.302 0.000
V20-V29 Motorcycle rider injured in transport accident
0.698 0.302 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.696 0.304 0.000
F10.9 Unspecified mental and behavioural disorder
0.696 0.304 0.000
F10.8 Other mental and behavioural disorders
0.696 0.304 0.000
F10.7 Residual and late-onset psychotic disorder
0.696 0.304 0.000
F10.6 Amnesic syndrome
0.696 0.304 0.000
F10.5 Psychotic disorder
0.696 0.304 0.000
I69.3 Sequelae of cerebral infarction
0.696 0.304 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.695 0.305 0.000
M25.7 Osteophyte
0.694 0.306 0.000
I42 Cardiomyopathy
0.694 0.306 0.000
D73 Diseases of spleen
0.694 0.306 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.694 0.306 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.693 0.307 0.000
M80-M85 Disorders of bone density and structure
0.693 0.307 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.692 0.308 0.000
T13 Other injuries of lower limb, level unspecified
0.692 0.308 0.000
I50.0 Congestive heart failure
0.692 0.308 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.692 0.308 0.000
I34.1 Mitral (valve) prolapse
0.692 0.308 0.000
H54 Blindness and low vision
0.690 0.310 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.690 0.310 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.689 0.311 0.000
Y40 Systemic antibiotics
0.689 0.311 0.000
F33 Recurrent depressive disorder
0.688 0.312 0.000
H53.6 Night blindness
0.688 0.312 0.000
H53.5 Colour vision deficiencies
0.688 0.312 0.000
H53.3 Other disorders of binocular vision
0.688 0.312 0.000
T95 Sequelae of burns, corrosions and frostbite
0.687 0.312 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.687 0.312 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.687 0.312 0.000
T79-T79 Certain early complications of trauma
0.687 0.312 0.000
H20 Iridocyclitis
0.687 0.313 0.000
B07 Viral warts
0.687 0.313 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.686 0.314 0.000
T93.2 Sequelae of other fractures of lower limb
0.685 0.315 0.000
W06 Fall involving bed
0.685 0.315 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.685 0.315 0.000
S51.9 Open wound of forearm, part unspecified
0.685 0.315 0.000
Y43.1 Antineoplastic antimetabolites
0.685 0.315 0.000
I52 Other heart disorders in diseases classified elsewhere
0.684 0.316 0.000
I48 Atrial fibrillation and flutter
0.684 0.316 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.684 0.316 0.000
I41 Myocarditis in diseases classified elsewhere
0.684 0.316 0.000
I40 Acute myocarditis
0.684 0.316 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.684 0.316 0.000
I32 Pericarditis in diseases classified elsewhere
0.684 0.316 0.000
Y44 Agents primarily affecting blood constituents
0.684 0.316 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.684 0.316 0.000
T14 Injury of unspecified body region
0.684 0.316 0.000
I46 Cardiac arrest
0.683 0.317 0.000
H36 Retinal disorders in diseases classified elsewhere
0.682 0.318 0.000
B37.4 Candidiasis of other urogenital sites
0.682 0.318 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.681 0.318 0.000
H43-H45 Disorders of vitreous body and globe
0.681 0.319 0.000
H25-H28 Disorders of lens
0.681 0.319 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.679 0.321 0.000
M45-M49 Spondylopathies
0.679 0.321 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.678 0.322 0.000
J30 Vasomotor and allergic rhinitis
0.678 0.322 0.000
Y86 Sequelae of other accidents
0.677 0.322 0.000
O72 Postpartum haemorrhage
0.677 0.323 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.677 0.323 0.000
D72.8 Other specified disorders of white blood cells
0.677 0.323 0.000
I50.1 Left ventricular failure
0.676 0.324 0.000
H21 Other disorders of iris and ciliary body
0.676 0.324 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.676 0.324 0.000
F31 Bipolar affective disorder
0.676 0.324 0.000
H04.4 Chronic inflammation of lachrymal passages
0.675 0.325 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.675 0.325 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.675 0.325 0.000
S46.0 Injury of tendon of the rotator cuff of shoulder
0.674 0.326 0.000
S51.0 Open wound of elbow
0.673 0.327 0.000
Chapter II Neoplasms
0.673 0.327 0.000
I72 Other aneurysm
0.673 0.327 0.000
J09-J18 Influenza and pneumonia
0.672 0.328 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.672 0.328 0.000
S32.0 Fracture of lumbar vertebra
0.671 0.329 0.000
M24 Other specific joint derangements
0.671 0.329 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.671 0.329 0.000
I95.9 Hypotension, unspecified
0.670 0.330 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.670 0.330 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.670 0.330 0.000
M25.54 Pain in joint (Hand)
0.670 0.330 0.000
B48 Other mycoses, not elsewhere classified
0.669 0.331 0.000
B47 Mycetoma
0.669 0.331 0.000
B46 Zygomycosis
0.669 0.331 0.000
B45 Cryptococcosis
0.669 0.331 0.000
B43 Chromomycosis and phaeomycotic abscess
0.669 0.331 0.000
B42 Sporotrichosis
0.669 0.331 0.000
B41 Paracoccidioidomycosis
0.669 0.331 0.000
B40 Blastomycosis
0.669 0.331 0.000
B39 Histoplasmosis
0.669 0.331 0.000
B38 Coccidioidomycosis
0.669 0.331 0.000
B36 Other superficial mycoses
0.669 0.331 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.668 0.332 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.668 0.332 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.667 0.333 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.666 0.334 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.666 0.334 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.666 0.334 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.664 0.336 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.664 0.336 0.000
H17 Corneal scars and opacities
0.664 0.336 0.000
H15 Disorders of sclera
0.664 0.336 0.000
I71.0 Dissection of aorta [any part]
0.663 0.336 0.000
H18.5 Hereditary corneal dystrophies
0.663 0.337 0.000
H90-H95 Other disorders of ear
0.663 0.337 0.000
I36 Nonrheumatic tricuspid valve disorders
0.663 0.337 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.663 0.337 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.663 0.337 0.000
E06.3 Autoimmune thyroiditis
0.661 0.339 0.000
S30.1 Contusion of abdominal wall
0.660 0.340 0.000
V80-V89 Other land transport accidents
0.660 0.340 0.000
A49 Bacterial infection of unspecified site
0.660 0.340 0.000
E03 Other hypothyroidism
0.660 0.340 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.660 0.340 0.000
H30 Chorioretinal inflammation
0.660 0.340 0.000
Chapter XXII Codes for special purposes
0.659 0.340 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.659 0.340 0.000
E85 Amyloidosis
0.659 0.341 0.000
E86 Volume depletion
0.659 0.341 0.000
I61.8 Other intracerebral haemorrhage
0.658 0.341 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.658 0.341 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.658 0.341 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.658 0.341 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.658 0.341 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.658 0.341 0.000
J38.4 Oedema of larynx
0.659 0.341 0.000
T91.9 Sequelae of unspecified injury of neck and trunk
0.658 0.342 0.000
H04.9 Disorder of lachrymal system, unspecified
0.658 0.342 0.000
M25.56 Pain in joint (Lower leg)
0.658 0.342 0.000
M60-M63 Disorders of muscles
0.657 0.343 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.657 0.343 0.000
H34 Retinal vascular occlusions
0.657 0.343 0.000
S90 Superficial injury of ankle and foot
0.657 0.343 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.656 0.344 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.656 0.344 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.656 0.344 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.656 0.344 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.656 0.344 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.656 0.344 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.655 0.345 0.000
F41 Other anxiety disorders
0.655 0.345 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.655 0.345 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.655 0.345 0.000
I67.5 Moyamoya disease
0.655 0.345 0.000
I67.4 Hypertensive encephalopathy
0.655 0.345 0.000
I67.3 Progressive vascular leukoencephalopathy
0.655 0.345 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.655 0.345 0.000
I67.8 Other specified cerebrovascular diseases
0.653 0.347 0.000
H18.4 Corneal degeneration
0.653 0.347 0.000
D70 Agranulocytosis
0.653 0.347 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.653 0.347 0.000
H53.1 Subjective visual disturbances
0.653 0.347 0.000
S80-S89 Injuries to the knee and lower leg
0.652 0.347 0.000
S46.2 Injury of muscle and tendon of other parts of biceps
0.652 0.347 0.000
I09 Other rheumatic heart diseases
0.652 0.348 0.000
I06 Rheumatic aortic valve diseases
0.652 0.348 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.652 0.348 0.000
F34 Persistent mood [affective] disorders
0.652 0.348 0.000
J95.0 Tracheostomy malfunction
0.651 0.349 0.000
M25.59 Pain in joint (Site unspecified)
0.650 0.350 0.000
B35 Dermatophytosis
0.649 0.350 0.000
M25.51 Pain in joint (Shoulder region)
0.648 0.352 0.000
I07 Rheumatic tricuspid valve diseases
0.648 0.352 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.648 0.352 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.647 0.353 0.000
S26 Injury of heart
0.647 0.353 0.000
S25 Injury of blood vessels of thorax
0.647 0.353 0.000
S24 Injury of nerves and spinal cord at thorax level
0.647 0.353 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.647 0.353 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.647 0.353 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.647 0.353 0.000
T98.1 Sequelae of other and unspecified effects of external causes
0.647 0.353 0.000
M21 Other acquired deformities of limbs
0.647 0.353 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.647 0.353 0.000
S22.4 Multiple fractures of ribs
0.646 0.354 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.646 0.354 0.000
S37 Injury of urinary and pelvic organs
0.646 0.354 0.000
S36 Injury of intra-abdominal organs
0.646 0.354 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.646 0.354 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.646 0.354 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.646 0.354 0.000
S31 Open wound of abdomen, lower back and pelvis
0.646 0.354 0.000
O66 Other obstructed labour
0.645 0.355 0.000
M40-M43 Deforming dorsopathies
0.645 0.355 0.000
I51.9 Heart disease, unspecified
0.645 0.355 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.644 0.356 0.000
D74 Methaemoglobinaemia
0.644 0.356 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.644 0.356 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.644 0.356 0.000
S52 Fracture of forearm
0.644 0.356 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.642 0.358 0.000
T91.1 Sequelae of fracture of spine
0.641 0.359 0.000
X78 Intentional self-harm by sharp object
0.640 0.360 0.000
Y49.2 Other and unspecified antidepressants
0.640 0.360 0.000
J38.7 Other diseases of larynx
0.640 0.360 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.639 0.361 0.000
C15-C26 Malignant neoplasms of digestive organs
0.639 0.361 0.000
D86 Sarcoidosis
0.639 0.361 0.000
J94 Other pleural conditions
0.638 0.362 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.637 0.362 0.000
I99 Other and unspecified disorders of circulatory system
0.637 0.363 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.637 0.363 0.000
S70 Superficial injury of hip and thigh
0.637 0.363 0.000
A40 Streptococcal septicaemia
0.637 0.363 0.000
J98.1 Pulmonary collapse
0.637 0.363 0.000
Y43.9 Primarily systemic agent, unspecified
0.636 0.364 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.636 0.364 0.000
Y43.6 Enzymes, not elsewhere classified
0.636 0.364 0.000
Y43.5 Acidifying and alkalising agents
0.636 0.364 0.000
Y43.2 Antineoplastic natural products
0.636 0.364 0.000
Y43.0 Antiallergic and antiemetic drugs
0.636 0.364 0.000
E65 Localised adiposity
0.636 0.364 0.000
F99 Mental disorder, not otherwise specified
0.635 0.365 0.000
M25.77 Osteophyte (Ankle and foot)
0.635 0.365 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.635 0.365 0.000
S51.8 Open wound of other parts of forearm
0.634 0.366 0.000
T91.3 Sequelae of injury of spinal cord
0.634 0.366 0.000
H04.8 Other disorders of lachrymal system
0.634 0.366 0.000
W13 Fall from, out of or through building or structure
0.634 0.366 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.633 0.367 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.633 0.367 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.633 0.367 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.633 0.367 0.000
B25 Cytomegaloviral disease
0.633 0.367 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.632 0.367 0.000
M84 Disorders of continuity of bone
0.633 0.367 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.632 0.368 0.000
J95.8 Other postprocedural respiratory disorders
0.632 0.368 0.000
S12 Fracture of neck
0.632 0.368 0.000
I51.5 Myocardial degeneration
0.631 0.369 0.000
I51.4 Myocarditis, unspecified
0.631 0.369 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.631 0.369 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.631 0.369 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.631 0.369 0.000
I51.0 Cardiac septal defect, acquired
0.631 0.369 0.000
S42.4 Fracture of lower end of humerus
0.631 0.369 0.000
O71 Other obstetric trauma
0.630 0.370 0.000
J92 Pleural plaque
0.630 0.370 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.629 0.371 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.629 0.371 0.000
Y52.7 Peripheral vasodilators
0.629 0.371 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.629 0.371 0.000
Y52.1 Calcium-channel blockers
0.629 0.371 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.629 0.371 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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