TreeWAS – Variant ID: rs16896068

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z45.0 Adjustment and management of cardiac pacemaker	0.000	0.933	0.067
J36 Peritonsillar abscess	0.000	0.936	0.064
H65.3 Chronic mucoid otitis media	0.045	0.955	0.000
K74.6 Other and unspecified cirrhosis of liver	0.044	0.956	0.000
H65 Nonsuppurative otitis media	0.042	0.958	0.000
K74 Fibrosis and cirrhosis of liver	0.041	0.959	0.000
H73.8 Other specified disorders of tympanic membrane	0.040	0.960	0.000
H65.4 Other chronic nonsuppurative otitis media	0.039	0.961	0.000
K74.3 Primary biliary cirrhosis	0.038	0.962	0.000
H73 Other disorders of tympanic membrane	0.036	0.964	0.000
K74.5 Biliary cirrhosis, unspecified	0.035	0.965	0.000
H65-H75 Diseases of middle ear and mastoid	0.033	0.967	0.000
H65.2 Chronic serous otitis media	0.032	0.968	0.000
H74 Other disorders of middle ear and mastoid	0.031	0.969	0.000
H65.0 Acute serous otitis media	0.030	0.970	0.000
K74.0 Hepatic fibrosis	0.030	0.970	0.000
H65.1 Other acute nonsuppurative otitis media	0.030	0.970	0.000
K74.4 Secondary biliary cirrhosis	0.030	0.970	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.030	0.970	0.000
K74.1 Hepatic sclerosis	0.030	0.970	0.000
K70-K77 Diseases of liver	0.028	0.972	0.000
H74.4 Polyp of middle ear	0.027	0.973	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.027	0.973	0.000
H73.1 Chronic myringitis	0.026	0.974	0.000
H73.0 Acute myringitis	0.026	0.974	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.026	0.974	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.026	0.974	0.000
K76.8 Other specified diseases of liver	0.025	0.975	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.024	0.976	0.000
H68 Eustachian salpingitis and obstruction	0.024	0.976	0.000
H67 Otitis media in diseases classified elsewhere	0.024	0.976	0.000
I10 Essential (primary) hypertension	0.024	0.976	0.000
H74.0 Tympanosclerosis	0.023	0.976	0.000
K76 Other diseases of liver	0.023	0.977	0.000
K73 Chronic hepatitis, not elsewhere classified	0.023	0.977	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.023	0.977	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.022	0.977	0.000
H69 Other disorders of Eustachian tube	0.022	0.978	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.022	0.978	0.000
H74.1 Adhesive middle ear disease	0.022	0.978	0.000
K70 Alcoholic liver disease	0.022	0.978	0.000
H70 Mastoiditis and related conditions	0.021	0.979	0.000
K72 Hepatic failure, not elsewhere classified	0.021	0.979	0.000
K75 Other inflammatory liver diseases	0.021	0.979	0.000
K77 Liver disorders in diseases classified elsewhere	0.020	0.980	0.000
K71 Toxic liver disease	0.020	0.980	0.000
K73.9 Chronic hepatitis, unspecified	0.020	0.980	0.000
H72 Perforation of tympanic membrane	0.019	0.981	0.000
K70.3 Alcoholic cirrhosis of liver	0.019	0.981	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.018	0.982	0.000
K75.4 Autoimmune hepatitis	0.018	0.982	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.017	0.982	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.017	0.982	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.017	0.982	0.000
H68.1 Obstruction of Eustachian tube	0.017	0.982	0.000
H68.0 Eustachian salpingitis	0.017	0.982	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.017	0.982	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.017	0.982	0.000
K76.7 Hepatorenal syndrome	0.017	0.983	0.000
K76.5 Hepatic veno-occlusive disease	0.017	0.983	0.000
K76.4 Peliosis hepatis	0.017	0.983	0.000
K76.3 Infarction of liver	0.017	0.983	0.000
K76.2 Central haemorrhagic necrosis of liver	0.017	0.983	0.000
K76.1 Chronic passive congestion of liver	0.017	0.983	0.000
K72.0 Acute and subacute hepatic failure	0.017	0.983	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.017	0.983	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.017	0.983	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.017	0.983	0.000
H69.8 Other specified disorders of Eustachian tube	0.017	0.983	0.000
H69.0 Patulous Eustachian tube	0.016	0.984	0.000
K72.1 Chronic hepatic failure	0.016	0.984	0.000
H70.8 Other mastoiditis and related conditions	0.016	0.984	0.000
K70.1 Alcoholic hepatitis	0.016	0.984	0.000
K70.0 Alcoholic fatty liver	0.016	0.984	0.000
K75.8 Other specified inflammatory liver diseases	0.015	0.984	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.015	0.984	0.000
H71 Cholesteatoma of middle ear	0.015	0.985	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.015	0.985	0.000
H70.2 Petrositis	0.015	0.985	0.000
H70.1 Chronic mastoiditis	0.015	0.985	0.000
H70.0 Acute mastoiditis	0.015	0.985	0.000
H72.1 Attic perforation of tympanic membrane	0.015	0.985	0.000
K75.2 Nonspecific reactive hepatitis	0.015	0.985	0.000
K75.1 Phlebitis of portal vein	0.015	0.985	0.000
K71.9 Toxic liver disease, unspecified	0.015	0.985	0.000
K71.8 Toxic liver disease with other disorders of liver	0.015	0.985	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.015	0.985	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.015	0.985	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.015	0.985	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.015	0.985	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.015	0.985	0.000
K71.2 Toxic liver disease with acute hepatitis	0.015	0.985	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.015	0.985	0.000
K71.0 Toxic liver disease with cholestasis	0.015	0.985	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.015	0.985	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.015	0.985	0.000
H72.2 Other marginal perforations of tympanic membrane	0.015	0.985	0.000
H72.0 Central perforation of tympanic membrane	0.014	0.986	0.000
H72.8 Other perforations of tympanic membrane	0.014	0.986	0.000
K76.6 Portal hypertension	0.014	0.986	0.000
K70.4 Alcoholic hepatic failure	0.013	0.987	0.000
H69.9 Eustachian tube disorder, unspecified	0.013	0.987	0.000
K29.6 Other gastritis	0.013	0.987	0.000
K75.0 Abscess of liver	0.012	0.988	0.000
K76.9 Liver disease, unspecified	0.012	0.988	0.000
Z90.1 Acquired absence of breast(s)	0.012	0.988	0.000
K70.9 Alcoholic liver disease, unspecified	0.012	0.988	0.000
H70.9 Mastoiditis, unspecified	0.011	0.989	0.000
K75.9 Inflammatory liver disease, unspecified	0.011	0.989	0.000
K72.9 Hepatic failure, unspecified	0.010	0.989	0.000
Z34.8 Supervision of other normal pregnancy	0.000	0.990	0.010
H66 Suppurative and unspecified otitis media	0.010	0.990	0.000
M51.2 Other specified intervertebral disk displacement	0.000	0.990	0.010
Z01.8 Other specified special examinations	0.009	0.991	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.000	0.991	0.009
M25.37 Other instability of joint (Ankle and foot)	0.008	0.992	0.000
Z90.0 Acquired absence of part of head and neck	0.008	0.992	0.000
M67.8 Other specified disorders of synovium and tendon	0.007	0.993	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.007	0.993	0.000
H66.0 Acute suppurative otitis media	0.007	0.993	0.000
M51 Other intervertebral disk disorders	0.000	0.993	0.007
H72.9 Perforation of tympanic membrane, unspecified	0.007	0.993	0.000
Z45 Adjustment and management of implanted device	0.000	0.993	0.007
H66.1 Chronic tubotympanic suppurative otitis media	0.006	0.993	0.000
H66.4 Suppurative otitis media, unspecified	0.006	0.993	0.000
M25.46 Effusion of joint (Lower leg)	0.006	0.994	0.000
N64.8 Other specified disorders of breast	0.006	0.994	0.000
M25.3 Other instability of joint	0.006	0.994	0.000
M51.4 Schmorl's nodes	0.000	0.994	0.006
Z45.3 Adjustment and management of implanted hearing device	0.000	0.994	0.006
M51.3 Other specified intervertebral disk degeneration	0.000	0.995	0.005
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.000	0.995	0.005
Chapter VIII Diseases of the ear and mastoid process	0.005	0.995	0.000
I89.0 Lymphoedema, not elsewhere classified	0.005	0.995	0.000
S62.50 Fracture of thumb (closed)	0.005	0.995	0.000
H66.3 Other chronic suppurative otitis media	0.005	0.995	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.005	0.995	0.000
S62.70 Multiple fractures of fingers (closed)	0.005	0.995	0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.005	0.995	0.000
M25.4 Effusion of joint	0.005	0.995	0.000
Z45.9 Adjustment and management of unspecified implanted device	0.000	0.995	0.005
Z45.1 Adjustment and management of infusion pump	0.000	0.995	0.005
M25.31 Other instability of joint (Shoulder region)	0.005	0.995	0.000
M25.36 Other instability of joint (Lower leg)	0.005	0.995	0.000
M25.42 Effusion of joint (Upper arm)	0.005	0.995	0.000
M51.8 Other specified intervertebral disk disorders	0.000	0.995	0.005
M25.39 Other instability of joint (Site unspecified)	0.004	0.995	0.000
M25.38 Other instability of joint (Other)	0.004	0.995	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.004	0.995	0.000
M25.32 Other instability of joint (Upper arm)	0.004	0.995	0.000
M25.30 Other instability of joint (Multiple sites)	0.004	0.995	0.000
S62.5 Fracture of thumb	0.004	0.996	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.004	0.996	0.000
Z34 Supervision of normal pregnancy	0.000	0.996	0.004
M25.34 Other instability of joint (Hand)	0.004	0.996	0.000
H43.3 Other vitreous opacities	0.004	0.996	0.000
M25.33 Other instability of joint (Forearm)	0.004	0.996	0.000
M25 Other joint disorders, not elsewhere classified	0.004	0.996	0.000
S62.7 Multiple fractures of fingers	0.004	0.996	0.000
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified	0.000	0.996	0.004
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region	0.000	0.996	0.004
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.000	0.996	0.004
M25.44 Effusion of joint (Hand)	0.004	0.996	0.000
H60-H62 Diseases of external ear	0.004	0.996	0.000
M25.9 Joint disorder, unspecified	0.004	0.996	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.996	0.004
S62.2 Fracture of first metacarpal bone	0.004	0.996	0.000
H43.1 Vitreous haemorrhage	0.004	0.996	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.000	0.996	0.004
M25.49 Effusion of joint (Site unspecified)	0.004	0.996	0.000
M25.48 Effusion of joint (Other)	0.004	0.996	0.000
M25.41 Effusion of joint (Shoulder region)	0.004	0.996	0.000
H60 Otitis externa	0.004	0.996	0.000
S62 Fracture at wrist and hand level	0.004	0.996	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.004	0.996	0.000
H60.8 Other otitis externa	0.004	0.996	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.004	0.996	0.000
S62.51 Fracture of thumb (open)	0.004	0.996	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.004	0.996	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.004	0.996	0.000
H43 Disorders of vitreous body	0.004	0.996	0.000
M47.86 Other spondylosis (Lumbar region)	0.000	0.996	0.004
H66.9 Otitis media, unspecified	0.003	0.996	0.000
Z90 Acquired absence of organs, not elsewhere classified	0.004	0.996	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.003	0.996	0.000
H60.1 Cellulitis of external ear	0.003	0.997	0.000
I22 Subsequent myocardial infarction	0.003	0.997	0.000
M25.40 Effusion of joint (Multiple sites)	0.003	0.997	0.000
Z90.5 Acquired absence of kidney	0.003	0.997	0.000
H60.2 Malignant otitis externa	0.003	0.997	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.003	0.997	0.000
I22.8 Subsequent myocardial infarction of other sites	0.003	0.997	0.000
M25.2 Flail joint	0.003	0.997	0.000
M25.1 Fistula of joint	0.003	0.997	0.000
M25.0 Haemarthrosis	0.003	0.997	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.003	0.997	0.000
S62.71 Multiple fractures of fingers (open)	0.003	0.997	0.000
M67 Other disorders of synovium and tendon	0.003	0.997	0.000
M51.9 Intervertebral disk disorder, unspecified	0.000	0.997	0.003
H43.8 Other disorders of vitreous body	0.003	0.997	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.003	0.997	0.000
M25.43 Effusion of joint (Forearm)	0.003	0.997	0.000
M25.8 Other specified joint disorders	0.003	0.997	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.003	0.997	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.003	0.997	0.000
M25.98 Joint disorder, unspecified (Other)	0.003	0.997	0.000
M25.94 Joint disorder, unspecified (Hand)	0.003	0.997	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.003	0.997	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.003	0.997	0.000
H92.1 Otorrhoea	0.003	0.997	0.000
I85.9 Oesophageal varices without bleeding	0.003	0.997	0.000
S62.3 Fracture of other metacarpal bone	0.003	0.997	0.000
S62.21 Fracture of first metacarpal bone (open)	0.003	0.997	0.000
G44.2 Tension-type headache	0.003	0.997	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.003	0.997	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.003	0.997	0.000
T81.4 Infection following a procedure, not elsewhere classified	0.003	0.997	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.003	0.997	0.000
M25.71 Osteophyte (Shoulder region)	0.003	0.997	0.000
H54.7 Unspecified visual loss	0.003	0.997	0.000
H60.4 Cholesteatoma of external ear	0.003	0.997	0.000
H60.5 Acute otitis externa, non-infective	0.003	0.997	0.000
H60.0 Abscess of external ear	0.003	0.997	0.000
S62.1 Fracture of other carpal bone(s)	0.003	0.997	0.000
H92 Otalgia and effusion of ear	0.003	0.997	0.000
H90-H95 Other disorders of ear	0.003	0.997	0.000
S62.4 Multiple fractures of metacarpal bones	0.003	0.997	0.000
H43.2 Crystalline deposits in vitreous body	0.003	0.997	0.000
H43.0 Vitreous prolapse	0.003	0.997	0.000
L30.9 Dermatitis, unspecified	0.003	0.997	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
Z90.3 Acquired absence of part of stomach	0.003	0.997	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.003	0.997	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.003	0.997	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.003	0.997	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.997	0.003
M25.72 Osteophyte (Upper arm)	0.003	0.997	0.000
Z34.0 Supervision of normal first pregnancy	0.000	0.997	0.003
I49.0 Ventricular fibrillation and flutter	0.000	0.997	0.003
M25.88 Other specified joint disorders (Other)	0.003	0.997	0.000
H60.3 Other infective otitis externa	0.002	0.997	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.003	0.997	0.000
M25.19 Fistula of joint (Site unspecified)	0.002	0.997	0.000
M25.18 Fistula of joint (Other)	0.002	0.997	0.000
M25.17 Fistula of joint (Ankle and foot)	0.002	0.997	0.000
M25.16 Fistula of joint (Lower leg)	0.002	0.997	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.002	0.997	0.000
M25.14 Fistula of joint (Hand)	0.002	0.997	0.000
M25.13 Fistula of joint (Forearm)	0.002	0.997	0.000
M25.12 Fistula of joint (Upper arm)	0.002	0.997	0.000
M25.11 Fistula of joint (Shoulder region)	0.002	0.997	0.000
M25.10 Fistula of joint (Multiple sites)	0.002	0.997	0.000
M25.29 Flail joint (Site unspecified)	0.002	0.997	0.000
M25.28 Flail joint (Other)	0.002	0.997	0.000
M25.27 Flail joint (Ankle and foot)	0.002	0.997	0.000
M25.26 Flail joint (Lower leg)	0.002	0.997	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.002	0.997	0.000
M25.24 Flail joint (Hand)	0.002	0.997	0.000
M25.23 Flail joint (Forearm)	0.002	0.997	0.000
M25.22 Flail joint (Upper arm)	0.002	0.997	0.000
M25.21 Flail joint (Shoulder region)	0.002	0.997	0.000
M25.20 Flail joint (Multiple sites)	0.002	0.997	0.000
M25.09 Haemarthrosis (Site unspecified)	0.002	0.997	0.000
M25.08 Haemarthrosis (Other)	0.002	0.997	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.002	0.997	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.002	0.997	0.000
M25.04 Haemarthrosis (Hand)	0.002	0.997	0.000
M25.03 Haemarthrosis (Forearm)	0.002	0.997	0.000
M25.02 Haemarthrosis (Upper arm)	0.002	0.997	0.000
M25.01 Haemarthrosis (Shoulder region)	0.002	0.997	0.000
M25.00 Haemarthrosis (Multiple sites)	0.002	0.997	0.000
C50.5 Lower-outer quadrant of breast	0.003	0.997	0.000
M25.83 Other specified joint disorders (Forearm)	0.003	0.997	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.002	0.997	0.000
M25.06 Haemarthrosis (Lower leg)	0.003	0.997	0.000
M25.86 Other specified joint disorders (Lower leg)	0.003	0.997	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.002	0.997	0.000
M25.84 Other specified joint disorders (Hand)	0.003	0.997	0.000
M25.7 Osteophyte	0.003	0.997	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.002	0.997	0.000
M67.3 Transient synovitis	0.002	0.997	0.000
M67.0 Short Achilles tendon (acquired)	0.002	0.997	0.000
W13.9 Unspecified place	0.000	0.997	0.003
M25.89 Other specified joint disorders (Site unspecified)	0.002	0.997	0.000
M25.82 Other specified joint disorders (Upper arm)	0.002	0.997	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.002	0.997	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.002	0.997	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.002	0.997	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.002	0.997	0.000
H62.2 Otitis externa in mycoses	0.002	0.997	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.002	0.997	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.002	0.997	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.002	0.997	0.000
S62.31 Fracture of other metacarpal bone (open)	0.002	0.997	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.997	0.002
S62.8 Fracture of other and unspecified parts of wrist and hand	0.002	0.997	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.002	0.998	0.000
M67.4 Ganglion	0.002	0.998	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.002	0.998	0.000
I95.9 Hypotension, unspecified	0.000	0.998	0.002
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.002	0.998	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.002	0.998	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.002	0.998	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.002	0.998	0.000
Z03.1 Observation for suspected malignant neoplasm	0.000	0.998	0.002
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.002	0.998	0.000
H92.2 Otorrhagia	0.002	0.998	0.000
I10-I15 Hypertensive diseases	0.002	0.998	0.000
C22.9 Liver, unspecified	0.002	0.998	0.000
H43.9 Disorder of vitreous body, unspecified	0.002	0.998	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.002	0.998	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.002	0.998	0.000
I95.2 Hypotension due to drugs	0.000	0.998	0.002
S62.40 Multiple fractures of metacarpal bones (closed)	0.002	0.998	0.000
H61.0 Perichondritis of external ear	0.002	0.998	0.000
H80-H83 Diseases of inner ear	0.002	0.998	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.002	0.998	0.000
Z45.2 Adjustment and management of vascular access device	0.000	0.998	0.002
M25.47 Effusion of joint (Ankle and foot)	0.002	0.998	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.002	0.998	0.000
M95.4 Acquired deformity of chest and rib	0.002	0.998	0.000
U80.0 Penicillin resistant agent	0.002	0.998	0.000
H61 Other disorders of external ear	0.002	0.998	0.000
M25.79 Osteophyte (Site unspecified)	0.002	0.998	0.000
M25.76 Osteophyte (Lower leg)	0.002	0.998	0.000
M25.73 Osteophyte (Forearm)	0.002	0.998	0.000
M25.70 Osteophyte (Multiple sites)	0.002	0.998	0.000
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.002	0.998	0.000
D41.0 Kidney	0.002	0.998	0.000
I85 Oesophageal varices	0.002	0.998	0.000
I85.0 Oesophageal varices with bleeding	0.002	0.998	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.998	0.002
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.998	0.002
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.998	0.002
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.998	0.002
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.002	0.998	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.002	0.998	0.000
H92.0 Otalgia	0.002	0.998	0.000
L91.0 Keloid scar	0.002	0.998	0.000
M67.49 Ganglion, multiple sites	0.002	0.998	0.000
M67.47 Ganglion, ankle and foot	0.002	0.998	0.000
M67.45 Ganglion, hip	0.002	0.998	0.000
C81.1 Nodular sclerosis	0.002	0.998	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.002	0.998	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.002	0.998	0.000
I95.0 Idiopathic hypotension	0.000	0.998	0.002
D36.7 Other specified sites	0.000	0.998	0.002
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.002	0.998	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
I21.4 Acute subendocardial myocardial infarction	0.002	0.998	0.000
I13 Hypertensive heart and renal disease	0.002	0.998	0.000
H61.9 Disorder of external ear, unspecified	0.002	0.998	0.000
J81 Pulmonary oedema	0.000	0.998	0.002
I95 Hypotension	0.000	0.998	0.002
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.998	0.002
M67.1 Other contracture of tendon (sheath)	0.002	0.998	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.002	0.998	0.000
H93 Other disorders of ear, not elsewhere classified	0.002	0.998	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.002	0.998	0.000
M67.43 Ganglion, wrist	0.002	0.998	0.000
E55.9 Vitamin D deficiency, unspecified	0.002	0.998	0.000
N70.9 Salpingitis and oophoritis, unspecified	0.000	0.998	0.002
T80.2 Infections following infusion, transfusion and therapeutic injection	0.002	0.998	0.000
Y45.0 Opioids and related analgesics	0.000	0.998	0.002
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.998	0.002
H61.3 Acquired stenosis of external ear canal	0.002	0.998	0.000
I95.8 Other hypotension	0.000	0.998	0.002
K44 Diaphragmatic hernia	0.002	0.998	0.000
C81.0 Lymphocytic predominance	0.002	0.998	0.000
D04.7 Skin of lower limb, including hip	0.000	0.998	0.002
M95.2 Other acquired deformity of head	0.002	0.998	0.000
K29.1 Other acute gastritis	0.002	0.998	0.000
L30.8 Other specified dermatitis	0.002	0.998	0.000
S62.6 Fracture of other finger	0.002	0.998	0.000
H93.3 Disorders of acoustic nerve	0.002	0.998	0.000
N87.1 Moderate cervical dysplasia	0.000	0.998	0.002
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
L30 Other dermatitis	0.002	0.998	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.998	0.001
Q05.9 Spina bifida, unspecified	0.002	0.998	0.000
G44 Other headache syndromes	0.002	0.998	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.002	0.998	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.002	0.998	0.000
Z45.8 Adjustment and management of other implanted devices	0.000	0.998	0.002
H83 Other diseases of inner ear	0.002	0.998	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.001	0.998	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.001	0.998	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.001	0.998	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.001	0.998	0.000
K57.2 Diverticular disease of large intestine with perforation and abscess	0.002	0.998	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.002	0.998	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.002	0.998	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.000	0.998	0.002
M48.00 Spinal stenosis (Multiple sites in spine)	0.000	0.998	0.002
H95.1 Other disorders following mastoidectomy	0.001	0.998	0.000
Q66.8 Other congenital deformities of feet	0.002	0.998	0.000
C81 Hodgkin's disease	0.002	0.998	0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.002	0.998	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.000	0.998	0.002
I21.0 Acute transmural myocardial infarction of anterior wall	0.002	0.998	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.002	0.998	0.000
I15 Secondary hypertension	0.001	0.998	0.001
Q66 Congenital deformities of feet	0.002	0.998	0.000
M25.78 Osteophyte (Other)	0.002	0.998	0.000
H93.2 Other abnormal auditory perceptions	0.001	0.998	0.000
H93.0 Degenerative and vascular disorders of ear	0.001	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.002	0.998	0.000
Q05 Spina bifida	0.002	0.998	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.002	0.998	0.000
Z90.8 Acquired absence of other organs	0.001	0.998	0.000
Z90.6 Acquired absence of other parts of urinary tract	0.001	0.998	0.000
C81.9 Hodgkin's disease, unspecified	0.002	0.998	0.000
G44.8 Other specified headache syndromes	0.002	0.998	0.000
K44.1 Diaphragmatic hernia with gangrene	0.001	0.998	0.000
T85.2 Mechanical complication of intraocular lens	0.002	0.998	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.001	0.998	0.000
C22.0 Liver cell carcinoma	0.002	0.998	0.000
H83.9 Disease of inner ear, unspecified	0.001	0.998	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.001	0.998	0.000
R49.0 Dysphonia	0.000	0.998	0.002
C81.2 Mixed cellularity	0.001	0.998	0.000
L30.5 Pityriasis alba	0.001	0.998	0.000
L30.4 Erythema intertrigo	0.001	0.998	0.000
L30.3 Infective dermatitis	0.001	0.998	0.000
L30.2 Cutaneous autosensitisation	0.001	0.998	0.000
L30.1 Dyshidrosis [pompholyx]	0.001	0.998	0.000
L30.0 Nummular dermatitis	0.001	0.998	0.000
M24.26 Disorder of ligament (Lower leg)	0.002	0.998	0.000
G44.0 Cluster headache syndrome	0.001	0.998	0.000
O03.9 Complete or unspecified, without complication	0.002	0.998	0.000
O03.4 Incomplete, without complication	0.002	0.998	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.002	0.998	0.000
H80 Otosclerosis	0.001	0.998	0.000
K29 Gastritis and duodenitis	0.002	0.998	0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.001	0.998	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.001	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.001	0.998	0.000
M25.77 Osteophyte (Ankle and foot)	0.002	0.998	0.000
G44.3 Chronic posttraumatic headache	0.001	0.998	0.000
G44.1 Vascular headache, not elsewhere classified	0.001	0.998	0.000
H93.8 Other specified disorders of ear	0.001	0.998	0.000
K13.0 Diseases of lips	0.000	0.998	0.002
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.001	0.998	0.000
M95.8 Other specified acquired deformities of musculoskeletal system	0.001	0.998	0.000
M95.5 Acquired deformity of pelvis	0.001	0.998	0.000
M95.3 Acquired deformity of neck	0.001	0.998	0.000
M95.1 Cauliflower ear	0.001	0.998	0.000
H83.3 Noise effects on inner ear	0.001	0.998	0.000
H83.2 Labyrinthine dysfunction	0.001	0.998	0.000
H83.1 Labyrinthine fistula	0.001	0.998	0.000
H91.3 Deaf mutism, not elsewhere classified	0.001	0.998	0.000
J04.0 Acute laryngitis	0.001	0.998	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.002	0.998	0.000
K29.0 Acute haemorrhagic gastritis	0.001	0.998	0.000
Q76.0 Spina bifida occulta	0.001	0.998	0.000
M48.09 Spinal stenosis (Site unspecified)	0.000	0.999	0.001
C22.1 Intrahepatic bile duct carcinoma	0.001	0.999	0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.001	0.999	0.000
Q76.5 Cervical rib	0.001	0.999	0.000
C81.7 Other Hodgkin's disease	0.001	0.999	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.001	0.999	0.000
C81.3 Lymphocytic depletion	0.001	0.999	0.000
I15.8 Other secondary hypertension	0.001	0.999	0.001
I15.2 Hypertension secondary to endocrine disorders	0.001	0.999	0.001
I15.0 Renovascular hypertension	0.001	0.999	0.001
Q66.2 Metatarsus varus	0.001	0.999	0.000
E55 Vitamin D deficiency	0.001	0.999	0.000
H91 Other hearing loss	0.001	0.999	0.000
H60.9 Otitis externa, unspecified	0.001	0.999	0.000
H83.8 Other specified diseases of inner ear	0.001	0.999	0.000
M48.0 Spinal stenosis	0.000	0.999	0.001
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.001	0.999	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.001	0.999	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.001	0.999	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.001	0.999	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.001	0.999	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.001	0.999	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.001	0.999	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.001	0.999	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.001	0.999	0.000
Q66.9 Congenital deformity of feet, unspecified	0.001	0.999	0.000
Q66.7 Pes cavus	0.001	0.999	0.000
Q66.5 Congenital pes planus	0.001	0.999	0.000
Q66.4 Talipes calcaneovalgus	0.001	0.999	0.000
Q66.1 Talipes calcaneovarus	0.001	0.999	0.000
Q66.0 Talipes equinovarus	0.001	0.999	0.000
T79.7 Traumatic subcutaneous emphysema	0.000	0.999	0.001
I11 Hypertensive heart disease	0.001	0.999	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.001	0.999	0.000
M21.26 Flexion deformity (Lower leg)	0.001	0.999	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.999	0.001
H61.1 Non-infective disorders of pinna	0.001	0.999	0.001
H93.9 Disorder of ear, unspecified	0.001	0.999	0.000
I15.1 Hypertension secondary to other renal disorders	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations