TreeWAS – Variant ID: rs16925298

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.998	0.002
Chapter V Mental and behavioural disorders	0.994	0.006
Chapter VIII Diseases of the ear and mastoid process	0.994	0.006
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.992	0.008
Chapter VI Diseases of the nervous system	0.985	0.015
Chapter XII Diseases of the skin and subcutaneous tissue	0.984	0.016
E10-E14 Diabetes mellitus	0.982	0.018
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.979	0.021
M65-M68 Disorders of synovium and tendon	0.978	0.022
L00-L08 Infections of the skin and subcutaneous tissue	0.978	0.022
H65-H75 Diseases of middle ear and mastoid	0.975	0.025
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.964	0.036
E10 Insulin-dependent diabetes mellitus	0.964	0.036
M65 Synovitis and tenosynovitis	0.963	0.037
S60-S69 Injuries to the wrist and hand	0.961	0.039
H65 Nonsuppurative otitis media	0.961	0.039
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.958	0.042
L02 Cutaneous abscess, furuncle and carbuncle	0.956	0.044
S50-S59 Injuries to the elbow and forearm	0.955	0.045
G50-G59 Nerve, nerve root and plexus disorders	0.944	0.056
M65.9 Synovitis and tenosynovitis, unspecified	0.940	0.060
E16 Other disorders of pancreatic internal secretion	0.940	0.060
Chapter XX External causes of morbidity and mortality	0.939	0.061
F10 Mental and behavioural disorders due to use of alcohol	0.937	0.063
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.934	0.066
D50-D53 Nutritional anaemias	0.931	0.069
S52 Fracture of forearm	0.925	0.075
E16.2 Hypoglycaemia, unspecified	0.922	0.078
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.914	0.086
H65.3 Chronic mucoid otitis media	0.910	0.090
F10.2 Dependence syndrome	0.904	0.096
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.900	0.100
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.900	0.100
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.897	0.103
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.896	0.104
D50 Iron deficiency anaemia	0.896	0.104
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.893	0.107
M80-M85 Disorders of bone density and structure	0.891	0.109
R19 Other symptoms and signs involving the digestive system and abdomen	0.890	0.110
M40-M43 Deforming dorsopathies	0.889	0.111
E20-E35 Disorders of other endocrine glands	0.888	0.112
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.888	0.112
T36-T50 Poisoning by drugs, medicaments and biological substances	0.885	0.115
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.885	0.115
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.872	0.128
T81 Complications of procedures, not elsewhere classified	0.872	0.128
M50-M54 Other dorsopathies	0.865	0.135
H90-H95 Other disorders of ear	0.861	0.139
L03 Cellulitis	0.861	0.139
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.860	0.140
S66 Injury of muscle and tendon at wrist and hand level	0.860	0.140
R19.4 Change in bowel habit	0.859	0.141
H65.4 Other chronic nonsuppurative otitis media	0.857	0.143
S20-S29 Injuries to the thorax	0.854	0.146
G00-G09 Inflammatory diseases of the central nervous system	0.848	0.152
D50.8 Other iron deficiency anaemias	0.848	0.152
E70-E90 Metabolic disorders	0.848	0.152
E11 Non-insulin-dependent diabetes mellitus	0.843	0.157
S52.5 Fracture of lower end of radius	0.843	0.157
H60-H62 Diseases of external ear	0.842	0.158
S90-S99 Injuries to the ankle and foot	0.839	0.161
S62 Fracture at wrist and hand level	0.836	0.164
R19.5 Other fecal abnormalities	0.833	0.167
S00-S09 Injuries to the head	0.833	0.167
D70-D77 Other diseases of blood and blood-forming organs	0.830	0.170
E10.2 With renal complications	0.829	0.171
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.824	0.176
R18 Ascites	0.823	0.177
L20-L30 Dermatitis and eczema	0.822	0.178
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.821	0.179
Y43 Primarily systemic agents	0.820	0.180
G62 Other polyneuropathies	0.820	0.180
R15 Faecal incontinence	0.814	0.186
E10.0 With coma	0.813	0.186
E83 Disorders of mineral metabolism	0.812	0.188
L08 Other local infections of skin and subcutaneous tissue	0.812	0.188
M65.3 Trigger finger	0.810	0.190
F10.1 Harmful use	0.809	0.191
T90 Sequelae of injuries of head	0.807	0.193
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.802	0.198
E10.6 With other specified complications	0.795	0.205
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.794	0.206
Chapter I Certain infectious and parasitic diseases	0.792	0.208
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.790	0.210
Chapter XV Pregnancy, childbirth and the puerperium	0.790	0.210
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.789	0.211
Chapter XXII Codes for special purposes	0.788	0.212
S67 Crushing injury of wrist and hand	0.788	0.212
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.787	0.213
T88 Other complications of surgical and medical care, not elsewhere classified	0.786	0.214
M84 Disorders of continuity of bone	0.785	0.215
G56 Mononeuropathies of upper limb	0.785	0.215
S52.50 Fracture of lower end of radius (closed)	0.784	0.216
S52.1 Fracture of upper end of radius	0.784	0.216
H65.9 Nonsuppurative otitis media, unspecified	0.784	0.216
H90 Conductive and sensorineural hearing loss	0.783	0.217
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.783	0.217
S40-S49 Injuries to the shoulder and upper arm	0.783	0.217
S64 Injury of nerves at wrist and hand level	0.782	0.218
E10.3 With ophthalmic complications	0.781	0.219
G51 Facial nerve disorders	0.778	0.222
M86-M90 Other osteopathies	0.777	0.223
R17 Unspecified jaundice	0.775	0.225
M41 Scoliosis	0.774	0.226
M67 Other disorders of synovium and tendon	0.774	0.226
E50-E64 Other nutritional deficiencies	0.772	0.227
H74 Other disorders of middle ear and mastoid	0.772	0.228
F00-F09 Organic, including symptomatic, mental disorders	0.772	0.228
E10.4 With neurological complications	0.771	0.229
H69 Other disorders of Eustachian tube	0.770	0.230
E83.1 Disorders of iron metabolism	0.768	0.232
T79-T79 Certain early complications of trauma	0.768	0.232
S10-S19 Injuries to the neck	0.766	0.234
E86 Volume depletion	0.765	0.235
G55.0 Nerve root and plexus compressions in neoplastic disease	0.764	0.236
G40-G47 Episodic and paroxysmal disorders	0.764	0.236
S02 Fracture of skull and facial bones	0.763	0.237
M54 Dorsalgia	0.762	0.238
H73 Other disorders of tympanic membrane	0.762	0.238
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.758	0.242
F30-F39 Mood [affective] disorders	0.758	0.242
X40-X49 Accidental poisoning by and exposure to noxious substances	0.756	0.243
F60-F69 Disorders of adult personality and behaviour	0.756	0.244
G80-G83 Cerebral palsy and other paralytic syndromes	0.756	0.244
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.755	0.245
E23 Hypofunction and other disorders of pituitary gland	0.755	0.245
L50-L54 Urticaria and erythema	0.752	0.248
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.751	0.249
S27 Injury of other and unspecified intrathoracic organs	0.751	0.249
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.750	0.250
E10.9 Without complications	0.750	0.250
S52.6 Fracture of lower end of both ulna and radius	0.747	0.253
T85 Complications of other internal prosthetic devices, implants and grafts	0.747	0.253
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.747	0.253
F80-F89 Disorders of psychological development	0.747	0.253
D55-D59 Haemolytic anaemias	0.745	0.255
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.745	0.255
G30-G32 Other degenerative diseases of the nervous system	0.745	0.255
M60-M63 Disorders of muscles	0.744	0.255
S62.6 Fracture of other finger	0.744	0.256
Chapter XXI Factors influencing health status and contact with health services	0.744	0.256
G59 Mononeuropathy in diseases classified elsewhere	0.744	0.256
G40 Epilepsy	0.744	0.256
H80-H83 Diseases of inner ear	0.743	0.257
L03.3 Cellulitis of trunk	0.743	0.257
G62.8 Other specified polyneuropathies	0.743	0.257
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.740	0.260
E13 Other specified diabetes mellitus	0.739	0.261
F99-F99 Unspecified mental disorder	0.739	0.261
T91 Sequelae of injuries of neck and trunk	0.738	0.262
M65.4 Radial styloid tenosynovitis [de Quervain]	0.738	0.262
H65.2 Chronic serous otitis media	0.738	0.262
W20-W49 Exposure to inanimate mechanical forces	0.737	0.263
M66 Spontaneous rupture of synovium and tendon	0.737	0.263
F12 Mental and behavioural disorders due to use of cannabinoids	0.735	0.265
G55.3 Nerve root and plexus compressions in other dorsopathies	0.733	0.267
E83.4 Disorders of magnesium metabolism	0.733	0.267
D50.9 Iron deficiency anaemia, unspecified	0.733	0.267
M70-M79 Other soft tissue disorders	0.733	0.267
V10-V19 Pedal cyclist injured in transport accident	0.732	0.268
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.732	0.268
E10.5 With peripheral circulatory complications	0.731	0.269
Z70-Z76 Persons encountering health services in other circumstances	0.731	0.269
G58 Other mononeuropathies	0.730	0.269
M43 Other deforming dorsopathies	0.728	0.271
M85 Other disorders of bone density and structure	0.728	0.271
M50 Cervical disk disorders	0.728	0.272
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.728	0.272
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.727	0.273
R13 Dysphagia	0.727	0.273
T81.8 Other complications of procedures, not elsewhere classified	0.727	0.273
L05 Pilonidal cyst	0.727	0.273
F10.4 Withdrawal state with delirium	0.726	0.274
G00 Bacterial meningitis, not elsewhere classified	0.726	0.274
V40-V49 Car occupant injured in transport accident	0.726	0.274
G56.0 Carpal tunnel syndrome	0.724	0.276
Y43.3 Other antineoplastic drugs	0.724	0.276
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.724	0.276
T66-T78 Other and unspecified effects of external causes	0.721	0.279
F20 Schizophrenia	0.720	0.280
S52.0 Fracture of upper end of ulna	0.720	0.280
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.719	0.281
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.719	0.281
M00-M03 Infectious arthropathies	0.718	0.281
E10.1 With ketoacidosis	0.718	0.282
E11.4 With neurological complications	0.718	0.282
D60-D64 Aplastic and other anaemias	0.718	0.282
F25 Schizoaffective disorders	0.718	0.282
M84.1 Nonunion of fracture [pseudarthrosis]	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.713	0.287
F70-F79 Mental retardation	0.713	0.287
E11.6 With other specified complications	0.712	0.288
G63 Polyneuropathy in diseases classified elsewhere	0.712	0.288
H61 Other disorders of external ear	0.712	0.288
X50-X57 Overexertion, travel and privation	0.711	0.289
Y45.0 Opioids and related analgesics	0.709	0.291
H71 Cholesteatoma of middle ear	0.707	0.293
E27 Other disorders of adrenal gland	0.707	0.293
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.707	0.293
O60-O75 Complications of labour and delivery	0.707	0.293
T90.2 Sequelae of fracture of skull and facial bones	0.706	0.293
L10-L14 Bullous disorders	0.706	0.294
H90.3 Sensorineural hearing loss, bilateral	0.705	0.295
F29 Unspecified nonorganic psychosis	0.705	0.295
E28 Ovarian dysfunction	0.705	0.295
E12 Malnutrition-related diabetes mellitus	0.704	0.296
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.704	0.296
L29 Pruritus	0.704	0.296
R05 Cough	0.704	0.296
Y60-Y69 Misadventures to patients during surgical and medical care	0.703	0.297
F52 Sexual dysfunction, not caused by organic disorder or disease	0.703	0.297
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.702	0.298
S51 Open wound of forearm	0.702	0.298
M45-M49 Spondylopathies	0.702	0.298
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.701	0.298
L04 Acute lymphadenitis	0.701	0.299
L01 Impetigo	0.701	0.299
L00 Staphylococcal scalded skin syndrome	0.701	0.299
G70-G73 Diseases of myoneural junction and muscle	0.700	0.300
M91-M94 Chondropathies	0.700	0.300
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.700	0.300
M65.34 Trigger finger-Hand	0.699	0.301
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.699	0.301
H70 Mastoiditis and related conditions	0.699	0.301
H68 Eustachian salpingitis and obstruction	0.699	0.301
H67 Otitis media in diseases classified elsewhere	0.699	0.301
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.697	0.303
T46 Poisoning by agents primarily affecting the cardiovascular system	0.695	0.304
E29 Testicular dysfunction	0.695	0.304
G90-G99 Other disorders of the nervous system	0.695	0.305
T81.9 Unspecified complication of procedure	0.694	0.306
S60 Superficial injury of wrist and hand	0.693	0.307
M41.9 Scoliosis, unspecified	0.692	0.308
E40-E46 Malnutrition	0.692	0.308
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.692	0.308
E15 Nondiabetic hypoglycaemic coma	0.691	0.309
R00 Abnormalities of heart beat	0.691	0.309
E10.8 With unspecified complications	0.691	0.309
E10.7 With multiple complications	0.691	0.309
M65.8 Other synovitis and tenosynovitis	0.691	0.309
M65.2 Calcific tendinitis	0.691	0.309
M65.1 Other infective (teno)synovitis	0.691	0.309
M65.0 Abscess of tendon sheath	0.691	0.309
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.690	0.310
H93 Other disorders of ear, not elsewhere classified	0.689	0.311
H65.1 Other acute nonsuppurative otitis media	0.689	0.311
H65.0 Acute serous otitis media	0.689	0.311
S65 Injury of blood vessels at wrist and hand level	0.689	0.311
V80-V89 Other land transport accidents	0.689	0.311
Y43.4 Immunosuppressive agents	0.688	0.312
X20-X29 Contact with venomous animals and plants	0.688	0.312
M54.3 Sciatica	0.688	0.312
T98 Sequelae of other and unspecified effects of external causes	0.687	0.313
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.687	0.313
F18 Mental and behavioural disorders due to use of volatile solvents	0.687	0.313
F16 Mental and behavioural disorders due to use of hallucinogens	0.687	0.313
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.687	0.313
F14 Mental and behavioural disorders due to use of cocaine	0.687	0.313
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.687	0.313
F11 Mental and behavioural disorders due to use of opioids	0.687	0.313
S52.8 Fracture of other parts of forearm	0.686	0.314
D68 Other coagulation defects	0.686	0.314
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.685	0.314
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.685	0.314
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.685	0.314
S59 Other and unspecified injuries of forearm	0.685	0.315
S58 Traumatic amputation of forearm	0.685	0.315
S57 Crushing injury of forearm	0.685	0.315
S56 Injury of muscle and tendon at forearm level	0.685	0.315
S55 Injury of blood vessels at forearm level	0.685	0.315
S54 Injury of nerves at forearm level	0.685	0.315
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.685	0.315
Z72 Problems related to lifestyle	0.685	0.315
Z73 Problems related to life-management difficulty	0.685	0.315
T86 Failure and rejection of transplanted organs and tissues	0.684	0.316
Y52 Agents primarily affecting the cardiovascular system	0.684	0.316
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.683	0.317
M82 Osteoporosis in diseases classified elsewhere	0.683	0.317
R12 Heartburn	0.683	0.317
L03.1 Cellulitis of other parts of limb	0.683	0.317
L08.8 Other specified local infections of skin and subcutaneous tissue	0.683	0.317
S52.10 Fracture of upper end of radius (closed)	0.683	0.317
T92 Sequelae of injuries of upper limb	0.681	0.319
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.680	0.320
Y51 Drugs primarily affecting the autonomic nervous system	0.678	0.322
S69 Other and unspecified injuries of wrist and hand	0.678	0.322
G53 Cranial nerve disorders in diseases classified elsewhere	0.677	0.323
G52 Disorders of other cranial nerves	0.677	0.323
S92 Fracture of foot, except ankle	0.676	0.324
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.676	0.324
R47-R49 Symptoms and signs involving speech and voice	0.676	0.324
F10.0 Acute intoxication	0.674	0.326
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.674	0.326
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.674	0.326
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.674	0.326
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.674	0.326
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.674	0.326
E16.9 Disorder of pancreatic internal secretion, unspecified	0.674	0.326
E16.8 Other specified disorders of pancreatic internal secretion	0.674	0.326
E16.4 Abnormal secretion of gastrin	0.674	0.326
E16.3 Increased secretion of glucagon	0.674	0.326
E16.1 Other hypoglycaemia	0.674	0.326
E16.0 Drug-induced hypoglycaemia without coma	0.674	0.326
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.673	0.327
Y35-Y36 Legal intervention and operations of war	0.673	0.327
Y10-Y34 Event of undetermined intent	0.673	0.327
Y00-Y09 Assault	0.673	0.327
X85-X99 Assault	0.673	0.327
X58-X59 Accidental exposure to other and unspecified factors	0.673	0.327
X30-X39 Exposure to forces of nature	0.673	0.327
X10-X19 Contact with heat and hot substances	0.673	0.327
X00-X09 Exposure to smoke, fire and flames	0.673	0.327
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.673	0.327
W75-W84 Other accidental threats to breathing	0.673	0.327
W65-W74 Accidental drowning and submersion	0.673	0.327
W50-W64 Exposure to animate mechanical forces	0.673	0.327
V98-V99 Other and unspecified transport accidents	0.673	0.327
V95-V97 Air and space transport accidents	0.673	0.327
V90-V94 Water transport accidents	0.673	0.327
V70-V79 Bus occupant injured in transport accident	0.673	0.327
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.673	0.327
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.673	0.327
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.673	0.327
V01-V09 Pedestrian injured in transport accident	0.673	0.327
E11.2 With renal complications	0.673	0.327
S62.61 Fracture of other finger (open)	0.673	0.327
V20-V29 Motorcycle rider injured in transport accident	0.672	0.328
F10.9 Unspecified mental and behavioural disorder	0.672	0.328
F10.8 Other mental and behavioural disorders	0.672	0.328
F10.7 Residual and late-onset psychotic disorder	0.672	0.328
F10.6 Amnesic syndrome	0.672	0.328
F10.5 Psychotic disorder	0.672	0.328
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.671	0.329
D70 Agranulocytosis	0.671	0.329
T39.1 4-Aminophenol derivatives	0.670	0.330
T87 Complications peculiar to reattachment and amputation	0.670	0.330
T80 Complications following infusion, transfusion and therapeutic injection	0.670	0.330
D51 Vitamin B12 deficiency anaemia	0.669	0.331
S27.0 Traumatic pneumothorax	0.669	0.331
D52 Folate deficiency anaemia	0.668	0.331
D53 Other nutritional anaemias	0.667	0.332
T81.7 Vascular complications following a procedure, not elsewhere classified	0.667	0.333
T15-T19 Effects of foreign body entering through natural orifice	0.666	0.334
Y45.2 Propionic acid derivatives	0.666	0.334
Y44 Agents primarily affecting blood constituents	0.666	0.334
T81.4 Infection following a procedure, not elsewhere classified	0.666	0.334
M80 Osteoporosis with pathological fracture	0.666	0.334
R79 Other abnormal findings of blood chemistry	0.665	0.335
F40-F48 Neurotic, stress-related and somatoform disorders	0.664	0.335
R72 Abnormality of white blood cells, not elsewhere classified	0.664	0.336
S67.0 Crushing injury of thumb and other finger(s)	0.663	0.336
S52.9 Fracture of forearm, part unspecified	0.663	0.337
S52.7 Multiple fractures of forearm	0.663	0.337
S52.4 Fracture of shafts of both ulna and radius	0.663	0.337
S52.3 Fracture of shaft of radius	0.663	0.337
S52.2 Fracture of shaft of ulna	0.663	0.337
S64.2 Injury of radial nerve at wrist and hand level	0.661	0.339
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.660	0.340
S02.2 Fracture of nasal bones	0.659	0.341
E23.0 Hypopituitarism	0.659	0.341
S70-S79 Injuries to the hip and thigh	0.658	0.342
G54 Nerve root and plexus disorders	0.657	0.342
Y57 Other and unspecified drugs and medicaments	0.657	0.343
S68 Traumatic amputation of wrist and hand	0.656	0.343
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.656	0.343
D73 Diseases of spleen	0.656	0.344
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.656	0.344
T95 Sequelae of burns, corrosions and frostbite	0.655	0.345
T94 Sequelae of injuries involving multiple and unspecified body regions	0.655	0.345
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.655	0.345
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.655	0.345
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.655	0.345
F23 Acute and transient psychotic disorders	0.654	0.346
E11.3 With ophthalmic complications	0.653	0.347
X60-X84 Intentional self-harm	0.653	0.347
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.652	0.348
E22 Hyperfunction of pituitary gland	0.652	0.348
S50 Superficial injury of forearm	0.651	0.349
L80-L99 Other disorders of the skin and subcutaneous tissue	0.651	0.349
G03 Meningitis due to other and unspecified causes	0.650	0.350
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.650	0.350
L03.9 Cellulitis, unspecified	0.649	0.351
G62.9 Polyneuropathy, unspecified	0.647	0.353
M54.1 Radiculopathy	0.647	0.353
L21 Seborrhoeic dermatitis	0.646	0.354
R95-R99 Ill-defined and unknown causes of mortality	0.645	0.355
G60 Hereditary and idiopathic neuropathy	0.645	0.355
G64 Other disorders of peripheral nervous system	0.645	0.355
L27 Dermatitis due to substances taken internally	0.645	0.355
R00.0 Tachycardia, unspecified	0.644	0.356
E11.5 With peripheral circulatory complications	0.644	0.356
Y59 Other and unspecified vaccines and biological substances	0.643	0.357
Y58 Bacterial vaccines	0.643	0.357
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.643	0.357
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.643	0.357
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.643	0.357
Y53 Agents primarily affecting the gastro-intestinal system	0.643	0.357
Y50 Central nervous system stimulants, not elsewhere classified	0.643	0.357
Y49 Psychotropic drugs, not elsewhere classified	0.643	0.357
Y48 Anaesthetics and therapeutic gases	0.643	0.357
Y47 Sedatives, hypnotics and antianxiety drugs	0.643	0.357
Y46 Antiepileptics and anti-Parkinsonism drugs	0.643	0.357
Y41 Other systemic anti-infectives and antiparasitics	0.643	0.357
H60 Otitis externa	0.643	0.357
F33 Recurrent depressive disorder	0.643	0.357
D50.1 Sideropenic dysphagia	0.642	0.357
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.642	0.358
T51 Toxic effect of alcohol	0.640	0.360
S99 Other and unspecified injuries of ankle and foot	0.639	0.360
G40.9 Epilepsy, unspecified	0.640	0.360
M83 Adult osteomalacia	0.638	0.361
R19.6 Halitosis	0.638	0.362
R19.3 Abdominal rigidity	0.638	0.362
R19.2 Visible peristalsis	0.638	0.362
R19.1 Abnormal bowel sounds	0.638	0.362
G00.1 Pneumococcal meningitis	0.638	0.362
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.638	0.362
M42 Spinal osteochondrosis	0.638	0.362
M40 Kyphosis and lordosis	0.638	0.362
E35 Disorders of endocrine glands in diseases classified elsewhere	0.637	0.363
E34 Other endocrine disorders	0.637	0.363
E32 Diseases of thymus	0.637	0.363
E31 Polyglandular dysfunction	0.637	0.363
E30 Disorders of puberty, not elsewhere classified	0.637	0.363
E26 Hyperaldosteronism	0.637	0.363
E25 Adrenogenital disorders	0.637	0.363
E24 Cushing's syndrome	0.637	0.363
E20 Hypoparathyroidism	0.637	0.363
M77 Other enthesopathies	0.637	0.363
F22 Persistent delusional disorders	0.636	0.364
F28 Other nonorganic psychotic disorders	0.636	0.364
F24 Induced delusional disorder	0.636	0.364
F21 Schizotypal disorder	0.636	0.364
L03.8 Cellulitis of other sites	0.636	0.364
G50 Disorders of trigeminal nerve	0.636	0.364
G55.2 Nerve root and plexus compressions in spondylosis	0.635	0.365
G61 Inflammatory polyneuropathy	0.635	0.365
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.635	0.365
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.635	0.365
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.635	0.365
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.635	0.365
T41 Poisoning by anaesthetics and therapeutic gases	0.635	0.365
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.635	0.365
T36 Poisoning by systemic antibiotics	0.635	0.365
T93 Sequelae of injuries of lower limb	0.634	0.366
G51.3 Clonic hemifacial spasm	0.633	0.366
D80-D89 Certain disorders involving the immune mechanism	0.633	0.367
B15-B19 Viral hepatitis	0.632	0.368
S91 Open wound of ankle and foot	0.632	0.368
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.632	0.368
T90.4 Sequelae of injury of eye and orbit	0.631	0.368
E61 Deficiency of other nutrient elements	0.629	0.371
M53 Other dorsopathies, not elsewhere classified	0.629	0.371
T88.7 Unspecified adverse effect of drug or medicament	0.629	0.371
S62.3 Fracture of other metacarpal bone	0.628	0.372
L50 Urticaria	0.627	0.373
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.626	0.374
O71 Other obstetric trauma	0.626	0.374
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.626	0.374
D69 Purpura and other haemorrhagic conditions	0.626	0.374
O68 Labour and delivery complicated by foetal stress [distress]	0.626	0.374
G82 Paraplegia and tetraplegia	0.625	0.375
E88 Other metabolic disorders	0.625	0.375
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.625	0.375
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.625	0.375
D72 Other disorders of white blood cells	0.624	0.376
Z72.1 Alcohol use	0.624	0.376
H69.9 Eustachian tube disorder, unspecified	0.623	0.377
M89 Other disorders of bone	0.623	0.377
Y40 Systemic antibiotics	0.621	0.379
M54.9 Dorsalgia, unspecified	0.621	0.379
F10.3 Withdrawal state	0.620	0.380
S52.60 Fracture of lower end of both ulna and radius (closed)	0.620	0.380
F02 Dementia in other diseases classified elsewhere	0.620	0.380
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.619	0.381
B95-B98 Bacterial, viral and other infectious agents	0.619	0.381
S20 Superficial injury of thorax	0.618	0.382
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.618	0.382
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.617	0.383
H94 Other disorders of ear in diseases classified elsewhere	0.617	0.383
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.617	0.383
G04 Encephalitis, myelitis and encephalomyelitis	0.617	0.383
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.616	0.383
S66.8 Injury of other muscles and tendons at wrist and hand level	0.616	0.383
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.616	0.383
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.616	0.383
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.616	0.383
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.616	0.383
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.616	0.383
E83.3 Disorders of phosphorus metabolism	0.616	0.383
S02.4 Fracture of malar and maxillary bones	0.616	0.384
F52.2 Failure of genital response	0.615	0.385
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.615	0.385

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations