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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16977508
log Bayes Factor = 17.5006
Chromosome 15   position 57,743,603  (GRCh37) Explore rs16977508 on Ensembl!
Variant rs16977508 is part of Cluster X0087

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.998 0.002 0.000
Chapter I Certain infectious and parasitic diseases
0.998 0.002 0.000
Chapter X Diseases of the respiratory system
0.997 0.003 0.000
G90-G99 Other disorders of the nervous system
0.995 0.005 0.000
Chapter XX External causes of morbidity and mortality
0.991 0.009 0.000
Chapter II Neoplasms
0.989 0.011 0.000
I20-I25 Ischaemic heart diseases
0.980 0.020 0.000
A30-A49 Other bacterial diseases
0.978 0.022 0.000
J95-J99 Other diseases of the respiratory system
0.976 0.024 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.975 0.025 0.000
Chapter XXI Factors influencing health status and contact with health services
0.975 0.025 0.000
B35-B49 Mycoses
0.970 0.030 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.968 0.032 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.967 0.033 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.967 0.033 0.000
T81 Complications of procedures, not elsewhere classified
0.966 0.034 0.000
G93 Other disorders of brain
0.966 0.034 0.000
Chapter XI Diseases of the digestive system
0.964 0.036 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.959 0.041 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.958 0.042 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.958 0.042 0.000
Z50 Care involving use of rehabilitation procedures
0.952 0.048 0.000
A41 Other septicaemia
0.951 0.049 0.000
I21 Acute myocardial infarction
0.947 0.053 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.946 0.054 0.000
B37 Candidiasis
0.945 0.055 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.942 0.058 0.000
E70-E90 Metabolic disorders
0.937 0.063 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.936 0.064 0.000
M70-M79 Other soft tissue disorders
0.933 0.067 0.000
Chapter VIII Diseases of the ear and mastoid process
0.932 0.068 0.000
R21 Rash and other nonspecific skin eruption
0.932 0.068 0.000
Y52 Agents primarily affecting the cardiovascular system
0.931 0.069 0.000
D00-D09 In situ neoplasms
0.931 0.069 0.000
R10 Abdominal and pelvic pain
0.930 0.070 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.930 0.070 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.929 0.071 0.000
I05-I09 Chronic rheumatic heart diseases
0.927 0.073 0.000
C50-C50 Malignant neoplasm of breast
0.926 0.074 0.000
E86 Volume depletion
0.926 0.074 0.000
J90-J94 Other diseases of pleura
0.924 0.076 0.000
K50-K52 Noninfective enteritis and colitis
0.923 0.077 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.921 0.079 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.921 0.079 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.918 0.082 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.917 0.083 0.000
G95 Other diseases of spinal cord
0.917 0.083 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.916 0.084 0.000
B37.0 Candidal stomatitis
0.915 0.085 0.000
K31 Other diseases of stomach and duodenum
0.911 0.089 0.000
R10.3 Pain localised to other parts of lower abdomen
0.911 0.089 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.910 0.090 0.000
K31.8 Other specified diseases of stomach and duodenum
0.910 0.090 0.000
S00-S09 Injuries to the head
0.905 0.095 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.904 0.096 0.000
H90-H95 Other disorders of ear
0.899 0.101 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.897 0.103 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.895 0.105 0.000
W20-W49 Exposure to inanimate mechanical forces
0.895 0.105 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.894 0.106 0.000
K29 Gastritis and duodenitis
0.893 0.107 0.000
R30-R39 Symptoms and signs involving the urinary system
0.892 0.108 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.890 0.110 0.000
H91 Other hearing loss
0.888 0.112 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.888 0.112 0.000
Q60-Q64 Congenital malformations of the urinary system
0.887 0.113 0.000
Z93 Artificial opening status
0.886 0.114 0.000
G91 Hydrocephalus
0.885 0.115 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.884 0.116 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.884 0.116 0.000
R32 Unspecified urinary incontinence
0.883 0.117 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.882 0.118 0.000
J98 Other respiratory disorders
0.882 0.118 0.000
C50 Malignant neoplasm of breast
0.881 0.119 0.000
H91.9 Hearing loss, unspecified
0.881 0.119 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.878 0.122 0.000
I27 Other pulmonary heart diseases
0.877 0.123 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.876 0.124 0.000
C60-C63 Malignant neoplasms of male genital organs
0.875 0.125 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.875 0.125 0.000
I60-I69 Cerebrovascular diseases
0.874 0.126 0.000
I22 Subsequent myocardial infarction
0.874 0.126 0.000
A41.9 Septicaemia, unspecified
0.873 0.127 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.869 0.131 0.000
M79.6 Pain in limb
0.868 0.132 0.000
I07 Rheumatic tricuspid valve diseases
0.866 0.134 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.866 0.134 0.000
J95.8 Other postprocedural respiratory disorders
0.864 0.136 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.862 0.138 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.860 0.140 0.000
M77 Other enthesopathies
0.859 0.141 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.857 0.143 0.000
Z92 Personal history of medical treatment
0.857 0.143 0.000
Chapter V Mental and behavioural disorders
0.857 0.143 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.857 0.143 0.000
R19.5 Other fecal abnormalities
0.857 0.143 0.000
G93.9 Disorder of brain, unspecified
0.855 0.145 0.000
K29.6 Other gastritis
0.853 0.147 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.852 0.148 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.852 0.148 0.000
K51 Ulcerative colitis
0.850 0.150 0.000
Z48 Other surgical follow-up care
0.847 0.153 0.000
J92 Pleural plaque
0.846 0.154 0.000
R10.0 Acute abdomen
0.846 0.154 0.000
Z93.6 Other artificial openings of urinary tract status
0.845 0.155 0.000
Z98 Other postsurgical states
0.843 0.157 0.000
I27.0 Primary pulmonary hypertension
0.841 0.159 0.000
K29.8 Duodenitis
0.840 0.160 0.000
I73 Other peripheral vascular diseases
0.839 0.161 0.000
G93.3 Postviral fatigue syndrome
0.838 0.162 0.000
G96 Other disorders of central nervous system
0.834 0.166 0.000
R16.1 Splenomegaly, not elsewhere classified
0.834 0.166 0.000
Z44 Fitting and adjustment of external prosthetic device
0.833 0.167 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.832 0.168 0.000
Z42 Follow-up care involving plastic surgery
0.830 0.170 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.829 0.171 0.000
G62 Other polyneuropathies
0.827 0.173 0.000
F30-F39 Mood [affective] disorders
0.827 0.173 0.000
G95.9 Disease of spinal cord, unspecified
0.826 0.174 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.825 0.175 0.000
I07.1 Tricuspid insufficiency
0.823 0.177 0.000
Z50.1 Other physical therapy
0.823 0.177 0.000
M79.7 Fibromyalgia
0.823 0.177 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.821 0.179 0.000
W25 Contact with sharp glass
0.821 0.179 0.000
C50.5 Lower-outer quadrant of breast
0.821 0.179 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.820 0.180 0.000
Z90.7 Acquired absence of genital organ(s)
0.820 0.180 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.820 0.180 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.819 0.181 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.818 0.182 0.000
Y43 Primarily systemic agents
0.818 0.182 0.000
C64-C68 Malignant neoplasms of urinary tract
0.816 0.184 0.000
J98.1 Pulmonary collapse
0.816 0.184 0.000
G93.8 Other specified disorders of brain
0.816 0.184 0.000
I25 Chronic ischaemic heart disease
0.815 0.185 0.000
J94 Other pleural conditions
0.815 0.185 0.000
S02 Fracture of skull and facial bones
0.813 0.187 0.000
Y52.1 Calcium-channel blockers
0.812 0.188 0.000
B95-B98 Bacterial, viral and other infectious agents
0.809 0.191 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.808 0.192 0.000
Q61 Cystic kidney disease
0.806 0.194 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.805 0.195 0.000
V10-V19 Pedal cyclist injured in transport accident
0.801 0.199 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.801 0.199 0.000
S40-S49 Injuries to the shoulder and upper arm
0.801 0.199 0.000
T85.2 Mechanical complication of intraocular lens
0.801 0.199 0.000
M79.1 Myalgia
0.800 0.200 0.000
Y83.6 Removal of other organ (partial) (total)
0.797 0.203 0.000
M79.0 Rheumatism, unspecified
0.797 0.203 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.797 0.203 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.797 0.203 0.000
K50 Crohn's disease [regional enteritis]
0.795 0.205 0.000
D05 Carcinoma in situ of breast
0.795 0.205 0.000
S20-S29 Injuries to the thorax
0.794 0.206 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.794 0.206 0.000
R11 Nausea and vomiting
0.794 0.206 0.000
S10-S19 Injuries to the neck
0.792 0.207 0.000
J60-J70 Lung diseases due to external agents
0.792 0.208 0.000
A80-A89 Viral infections of the central nervous system
0.792 0.208 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.791 0.209 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.791 0.209 0.000
A49 Bacterial infection of unspecified site
0.790 0.210 0.000
Z48.0 Attention to surgical dressings and sutures
0.787 0.213 0.000
G40-G47 Episodic and paroxysmal disorders
0.787 0.213 0.000
Z41 Procedures for purposes other than remedying health state
0.787 0.213 0.000
E00-E07 Disorders of thyroid gland
0.785 0.215 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.785 0.215 0.000
A00-A09 Intestinal infectious diseases
0.784 0.216 0.000
Q50-Q56 Congenital malformations of genital organs
0.784 0.216 0.000
K51.9 Ulcerative colitis, unspecified
0.783 0.217 0.000
S90-S99 Injuries to the ankle and foot
0.782 0.218 0.000
K70-K77 Diseases of liver
0.781 0.219 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.778 0.222 0.000
J00-J06 Acute upper respiratory infections
0.776 0.224 0.000
I30-I52 Other forms of heart disease
0.776 0.224 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.775 0.225 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.774 0.226 0.000
Y83.4 Other reconstructive surgery
0.774 0.226 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.773 0.227 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.773 0.227 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.771 0.229 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.771 0.229 0.000
C61 Malignant neoplasm of prostate
0.770 0.230 0.000
W25.9 Unspecified place
0.769 0.231 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.768 0.232 0.000
G60 Hereditary and idiopathic neuropathy
0.767 0.233 0.000
B37.1 Pulmonary candidiasis
0.767 0.233 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.766 0.233 0.000
I73.9 Peripheral vascular disease, unspecified
0.766 0.234 0.000
Z80 Family history of malignant neoplasm
0.765 0.235 0.000
D70 Agranulocytosis
0.765 0.235 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.765 0.235 0.000
I21.4 Acute subendocardial myocardial infarction
0.764 0.236 0.000
G95.0 Syringomyelia and syringobulbia
0.763 0.237 0.000
Z98.0 Intestinal bypass and anastomosis status
0.762 0.238 0.000
G62.9 Polyneuropathy, unspecified
0.760 0.240 0.000
G91.9 Hydrocephalus, unspecified
0.759 0.241 0.000
B49 Unspecified mycosis
0.759 0.241 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.759 0.241 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.759 0.241 0.000
E20-E35 Disorders of other endocrine glands
0.758 0.242 0.000
G90 Disorders of autonomic nervous system
0.758 0.242 0.000
I05 Rheumatic mitral valve diseases
0.757 0.243 0.000
A40 Streptococcal septicaemia
0.756 0.244 0.000
M79.8 Other specified soft tissue disorders
0.756 0.244 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.755 0.244 0.000
Chapter XXII Codes for special purposes
0.755 0.245 0.000
J92.9 Pleural plaque without asbestos
0.755 0.245 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.754 0.246 0.000
R25 Abnormal involuntary movements
0.754 0.246 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.753 0.247 0.000
J20-J22 Other acute lower respiratory infections
0.753 0.247 0.000
G20-G26 Extrapyramidal and movement disorders
0.752 0.248 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.752 0.248 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.752 0.248 0.000
Z73 Problems related to life-management difficulty
0.752 0.248 0.000
W50-W64 Exposure to animate mechanical forces
0.752 0.248 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.751 0.249 0.000
S60-S69 Injuries to the wrist and hand
0.751 0.249 0.000
C92 Myeloid leukaemia
0.750 0.249 0.000
M77.9 Enthesopathy, unspecified
0.750 0.250 0.000
J81 Pulmonary oedema
0.749 0.251 0.000
D04 Carcinoma in situ of skin
0.749 0.251 0.000
I73.0 Raynaud's syndrome
0.748 0.252 0.000
Z50.0 Cardiac rehabilitation
0.748 0.252 0.000
Q61.0 Congenital single renal cyst
0.748 0.252 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.747 0.253 0.000
M79.79 Fibromyalgia (Site unspecified)
0.747 0.253 0.000
T79-T79 Certain early complications of trauma
0.746 0.254 0.000
Z54 Convalescence
0.746 0.254 0.000
I24 Other acute ischaemic heart diseases
0.744 0.256 0.000
B65-B83 Helminthiases
0.744 0.256 0.000
S00 Superficial injury of head
0.744 0.256 0.000
Z90.1 Acquired absence of breast(s)
0.743 0.257 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.743 0.257 0.000
Z44.3 Fitting and adjustment of external breast prosthesis
0.742 0.258 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.740 0.260 0.000
Z92.3 Personal history of irradiation
0.740 0.260 0.000
S05 Injury of eye and orbit
0.740 0.260 0.000
I25.1 Atherosclerotic heart disease
0.739 0.261 0.000
Q80-Q89 Other congenital malformations
0.739 0.261 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.738 0.262 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.738 0.262 0.000
Z74 Problems related to care-provider dependency
0.737 0.263 0.000
C50.3 Lower-inner quadrant of breast
0.736 0.264 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.735 0.265 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.735 0.265 0.000
G61 Inflammatory polyneuropathy
0.734 0.266 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.734 0.266 0.000
C50.0 Nipple and areola
0.733 0.267 0.000
D05.1 Intraductal carcinoma in situ
0.733 0.267 0.000
G93.0 Cerebral cysts
0.732 0.268 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.732 0.268 0.000
H65-H75 Diseases of middle ear and mastoid
0.732 0.268 0.000
M91-M94 Chondropathies
0.731 0.269 0.000
M80-M85 Disorders of bone density and structure
0.731 0.269 0.000
J40-J47 Chronic lower respiratory diseases
0.731 0.269 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.731 0.269 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.731 0.269 0.000
B37.3 Candidiasis of vulva and vagina
0.730 0.270 0.000
J90 Pleural effusion, not elsewhere classified
0.729 0.271 0.000
G91.1 Obstructive hydrocephalus
0.729 0.271 0.000
M77.1 Lateral epicondylitis
0.727 0.273 0.000
F31 Bipolar affective disorder
0.726 0.274 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.724 0.275 0.000
G93.6 Cerebral oedema
0.724 0.276 0.000
B37.8 Candidiasis of other sites
0.724 0.276 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.723 0.277 0.000
Z52 Donors of organs and tissues
0.723 0.277 0.000
F33 Recurrent depressive disorder
0.723 0.277 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.721 0.279 0.000
G30-G32 Other degenerative diseases of the nervous system
0.719 0.281 0.000
G96.0 Cerebrospinal fluid leak
0.718 0.282 0.000
K31.1 Adult hypertrophic pyloric stenosis
0.718 0.282 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.718 0.282 0.000
X60-X84 Intentional self-harm
0.718 0.282 0.000
Z93.3 Colostomy status
0.717 0.283 0.000
E87.3 Alkalosis
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
E50-E64 Other nutritional deficiencies
0.717 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.716 0.284 0.000
T86 Failure and rejection of transplanted organs and tissues
0.716 0.284 0.000
T90 Sequelae of injuries of head
0.716 0.284 0.000
E83 Disorders of mineral metabolism
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.716 0.284 0.000
W29 Contact with other powered hand tools and household machinery
0.716 0.284 0.000
M79.60 Pain in limb (Multiple sites)
0.715 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.715 0.284 0.000
B99-B99 Other infectious diseases
0.715 0.285 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.715 0.285 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.715 0.285 0.000
B50-B64 Protozoal diseases
0.715 0.285 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.715 0.285 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.715 0.285 0.000
A75-A79 Rickettsioses
0.715 0.285 0.000
A70-A74 Other diseases caused by chlamydiae
0.715 0.285 0.000
A65-A69 Other spirochaetal diseases
0.715 0.285 0.000
A20-A28 Certain zoonotic bacterial diseases
0.715 0.285 0.000
A15-A19 Tuberculosis
0.715 0.285 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.715 0.285 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.714 0.285 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.714 0.286 0.000
M79.61 Pain in limb (Shoulder region)
0.714 0.286 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.714 0.286 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.714 0.286 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.714 0.286 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.714 0.286 0.000
G92 Toxic encephalopathy
0.714 0.286 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.713 0.287 0.000
S70-S79 Injuries to the hip and thigh
0.713 0.287 0.000
R34 Anuria and oliguria
0.713 0.287 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.712 0.288 0.000
A41.8 Other specified septicaemia
0.712 0.288 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.711 0.289 0.000
Y10-Y34 Event of undetermined intent
0.711 0.289 0.000
Y00-Y09 Assault
0.711 0.289 0.000
X85-X99 Assault
0.711 0.289 0.000
X50-X57 Overexertion, travel and privation
0.711 0.289 0.000
X30-X39 Exposure to forces of nature
0.711 0.289 0.000
X20-X29 Contact with venomous animals and plants
0.711 0.289 0.000
X10-X19 Contact with heat and hot substances
0.711 0.289 0.000
X00-X09 Exposure to smoke, fire and flames
0.711 0.289 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.711 0.289 0.000
W75-W84 Other accidental threats to breathing
0.711 0.289 0.000
W65-W74 Accidental drowning and submersion
0.711 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.711 0.289 0.000
V95-V97 Air and space transport accidents
0.711 0.289 0.000
V90-V94 Water transport accidents
0.711 0.289 0.000
V80-V89 Other land transport accidents
0.711 0.289 0.000
V70-V79 Bus occupant injured in transport accident
0.711 0.289 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.711 0.289 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.711 0.289 0.000
V40-V49 Car occupant injured in transport accident
0.711 0.289 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.711 0.289 0.000
V01-V09 Pedestrian injured in transport accident
0.711 0.289 0.000
J98.6 Disorders of diaphragm
0.710 0.290 0.000
I67 Other cerebrovascular diseases
0.710 0.290 0.000
S06 Intracranial injury
0.710 0.290 0.000
M79.62 Pain in limb (Upper arm)
0.710 0.290 0.000
C50.2 Upper-inner quadrant of breast
0.710 0.290 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.709 0.291 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.708 0.292 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.708 0.292 0.000
Z50.5 Speech therapy
0.708 0.292 0.000
M79.64 Pain in limb (Hand)
0.708 0.292 0.000
Q25 Congenital malformations of great arteries
0.708 0.292 0.000
K52 Other non-infective gastro-enteritis and colitis
0.706 0.294 0.000
M76 Enthesopathies of lower limb, excluding foot
0.705 0.294 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.705 0.295 0.000
K29.3 Chronic superficial gastritis
0.705 0.295 0.000
T92 Sequelae of injuries of upper limb
0.702 0.298 0.000
I23 Certain current complications following acute myocardial infarction
0.702 0.298 0.000
K29.1 Other acute gastritis
0.702 0.298 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.701 0.299 0.000
A48 Other bacterial diseases, not elsewhere classified
0.701 0.299 0.000
A44 Bartonellosis
0.701 0.299 0.000
A43 Nocardiosis
0.701 0.299 0.000
A42 Actinomycosis
0.701 0.299 0.000
A39 Meningococcal infection
0.701 0.299 0.000
A37 Whooping cough
0.701 0.299 0.000
A36 Diphtheria
0.701 0.299 0.000
A32 Listeriosis
0.701 0.299 0.000
A31 Infection due to other mycobacteria
0.701 0.299 0.000
A30 Leprosy [Hansen's disease]
0.701 0.299 0.000
A46 Erysipelas
0.701 0.299 0.000
A38 Scarlet fever
0.701 0.299 0.000
A35 Other tetanus
0.701 0.299 0.000
A34 Obstetrical tetanus
0.701 0.299 0.000
A33 Tetanus neonatorum
0.701 0.299 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.700 0.300 0.000
J92.0 Pleural plaque with presence of asbestos
0.700 0.300 0.000
J96 Respiratory failure, not elsewhere classified
0.699 0.300 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.699 0.301 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.699 0.301 0.000
Q35-Q37 Cleft lip and cleft palate
0.699 0.301 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.699 0.301 0.000
Q00-Q07 Congenital malformations of the nervous system
0.699 0.301 0.000
D03 Melanoma in situ
0.699 0.301 0.000
G93.4 Encephalopathy, unspecified
0.698 0.302 0.000
K51.8 Other ulcerative colitis
0.697 0.303 0.000
D69 Purpura and other haemorrhagic conditions
0.697 0.303 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.696 0.304 0.000
R19.4 Change in bowel habit
0.696 0.304 0.000
Z87 Personal history of other diseases and conditions
0.696 0.304 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.696 0.304 0.000
Z93.5 Cystostomy status
0.696 0.304 0.000
B48 Other mycoses, not elsewhere classified
0.696 0.304 0.000
B47 Mycetoma
0.696 0.304 0.000
B46 Zygomycosis
0.696 0.304 0.000
B45 Cryptococcosis
0.696 0.304 0.000
B43 Chromomycosis and phaeomycotic abscess
0.696 0.304 0.000
B42 Sporotrichosis
0.696 0.304 0.000
B41 Paracoccidioidomycosis
0.696 0.304 0.000
B40 Blastomycosis
0.696 0.304 0.000
B39 Histoplasmosis
0.696 0.304 0.000
B38 Coccidioidomycosis
0.696 0.304 0.000
B36 Other superficial mycoses
0.696 0.304 0.000
B35 Dermatophytosis
0.696 0.304 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.695 0.305 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.694 0.306 0.000
M60-M63 Disorders of muscles
0.694 0.306 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.694 0.306 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.694 0.306 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.694 0.306 0.000
M79.19 Myalgia (Site unspecified)
0.694 0.306 0.000
Y59 Other and unspecified vaccines and biological substances
0.693 0.307 0.000
Y58 Bacterial vaccines
0.693 0.307 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.693 0.307 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.693 0.307 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.693 0.307 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.693 0.307 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.693 0.307 0.000
Y48 Anaesthetics and therapeutic gases
0.693 0.307 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.693 0.307 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.693 0.307 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.693 0.307 0.000
S50-S59 Injuries to the elbow and forearm
0.693 0.307 0.000
I45 Other conduction disorders
0.693 0.307 0.000
R18 Ascites
0.693 0.307 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.693 0.307 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.693 0.307 0.000
G93.7 Reye's syndrome
0.692 0.307 0.000
G93.5 Compression of brain
0.692 0.307 0.000
G93.2 Benign intracranial hypertension
0.692 0.307 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.692 0.307 0.000
B44 Aspergillosis
0.692 0.308 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.692 0.308 0.000
I49 Other cardiac arrhythmias
0.691 0.309 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.691 0.309 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.691 0.309 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.690 0.310 0.000
R45 Symptoms and signs involving emotional state
0.690 0.310 0.000
I61 Intracerebral haemorrhage
0.689 0.311 0.000
Z43 Attention to artificial openings
0.689 0.311 0.000
T81.9 Unspecified complication of procedure
0.688 0.311 0.000
K27 Peptic ulcer, site unspecified
0.688 0.311 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.688 0.312 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.688 0.312 0.000
I26 Pulmonary embolism
0.687 0.313 0.000
Z80.3 Family history of malignant neoplasm of breast
0.687 0.313 0.000
K90-K93 Other diseases of the digestive system
0.687 0.313 0.000
K75 Other inflammatory liver diseases
0.687 0.313 0.000
E40-E46 Malnutrition
0.686 0.313 0.000
Z92.8 Personal history of other medical treatment
0.686 0.314 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.686 0.314 0.000
I60 Subarachnoid haemorrhage
0.686 0.314 0.000
B15-B19 Viral hepatitis
0.685 0.315 0.000
R42 Dizziness and giddiness
0.685 0.315 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.685 0.315 0.000
M79.67 Pain in limb (Ankle and foot)
0.685 0.315 0.000
Z72 Problems related to lifestyle
0.685 0.315 0.000
F30 Manic episode
0.684 0.316 0.000
I63 Cerebral infarction
0.684 0.316 0.000
C81 Hodgkin's disease
0.683 0.317 0.000
C62 Malignant neoplasm of testis
0.683 0.317 0.000
Z50.6 Orthoptic training
0.682 0.317 0.000
Z50.3 Drug rehabilitation
0.682 0.317 0.000
A41.4 Septicaemia due to anaerobes
0.682 0.318 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.682 0.318 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.682 0.318 0.000
J94.8 Other specified pleural conditions
0.682 0.318 0.000
A49.8 Other bacterial infections of unspecified site
0.682 0.318 0.000
V20-V29 Motorcycle rider injured in transport accident
0.680 0.320 0.000
Q23 Congenital malformations of aortic and mitral valves
0.679 0.321 0.000
J94.2 Haemothorax
0.679 0.321 0.000
E03 Other hypothyroidism
0.679 0.321 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.679 0.321 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.679 0.321 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.679 0.321 0.000
M79.5 Residual foreign body in soft tissue
0.678 0.322 0.000
B37.7 Candidal septicaemia
0.677 0.322 0.000
B37.6 Candidal endocarditis
0.677 0.322 0.000
B37.5 Candidal meningitis
0.677 0.322 0.000
B37.4 Candidiasis of other urogenital sites
0.677 0.322 0.000
B37.2 Candidiasis of skin and nail
0.677 0.322 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.676 0.324 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.676 0.324 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.676 0.324 0.000
T82.3 Mechanical complication of other vascular grafts
0.676 0.324 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.676 0.324 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.676 0.324 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.676 0.324 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.675 0.325 0.000
M79.69 Pain in limb (Site unspecified)
0.674 0.326 0.000
Y44 Agents primarily affecting blood constituents
0.674 0.326 0.000
Q63 Other congenital malformations of kidney
0.673 0.327 0.000
M86-M90 Other osteopathies
0.673 0.327 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.673 0.327 0.000
S02.4 Fracture of malar and maxillary bones
0.673 0.327 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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