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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17080093
log Bayes Factor = 8.15354
Chromosome 6   position 150,997,440  (GRCh37) Explore rs17080093 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I10 Essential (primary) hypertension
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.093 0.907
I11 Hypertensive heart disease
0.000 0.208 0.792
I20-I25 Ischaemic heart diseases
0.000 0.221 0.779
I25 Chronic ischaemic heart disease
0.000 0.230 0.770
Chapter IX Diseases of the circulatory system
0.000 0.234 0.766
I24 Other acute ischaemic heart diseases
0.000 0.236 0.764
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.240 0.760
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.250 0.750
I21 Acute myocardial infarction
0.000 0.284 0.716
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.290 0.710
I12 Hypertensive renal disease
0.000 0.309 0.691
I25.1 Atherosclerotic heart disease
0.000 0.312 0.688
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.341 0.659
I13 Hypertensive heart and renal disease
0.000 0.350 0.650
I60-I69 Cerebrovascular diseases
0.000 0.360 0.640
I24.8 Other forms of acute ischaemic heart disease
0.000 0.383 0.617
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.390 0.610
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.400 0.600
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.401 0.599
I67 Other cerebrovascular diseases
0.000 0.413 0.587
I15 Secondary hypertension
0.000 0.415 0.585
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.432 0.568
I25.2 Old myocardial infarction
0.000 0.439 0.561
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.439 0.561
I23 Certain current complications following acute myocardial infarction
0.000 0.441 0.559
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.441 0.559
I25.4 Coronary artery aneurysm
0.000 0.444 0.556
I25.6 Silent myocardial ischaemia
0.000 0.448 0.552
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.448 0.552
I00-I02 Acute rheumatic fever
0.000 0.451 0.549
I67.8 Other specified cerebrovascular diseases
0.000 0.470 0.530
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.476 0.524
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.479 0.521
I12.0 Hypertensive renal disease with renal failure
0.000 0.481 0.519
I12.9 Hypertensive renal disease without renal failure
0.000 0.485 0.515
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.487 0.513
I65.2 Occlusion and stenosis of carotid artery
0.000 0.496 0.504
I05-I09 Chronic rheumatic heart diseases
0.000 0.504 0.496
I67.1 Cerebral aneurysm, nonruptured
0.000 0.518 0.482
I25.5 Ischaemic cardiomyopathy
0.000 0.525 0.475
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.534 0.466
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.534 0.466
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.534 0.466
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.534 0.466
I24.1 Dressler's syndrome
0.000 0.537 0.463
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.541 0.459
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.541 0.459
I67.9 Cerebrovascular disease, unspecified
0.000 0.549 0.451
I21.9 Acute myocardial infarction, unspecified
0.000 0.551 0.449
I22 Subsequent myocardial infarction
0.000 0.554 0.446
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.001 0.560 0.439
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.564 0.436
I67.2 Cerebral atherosclerosis
0.000 0.567 0.433
I63 Cerebral infarction
0.000 0.567 0.433
I20 Angina pectoris
0.000 0.569 0.431
I05 Rheumatic mitral valve diseases
0.000 0.576 0.424
I21.4 Acute subendocardial myocardial infarction
0.000 0.578 0.422
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.579 0.421
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.579 0.421
I67.5 Moyamoya disease
0.000 0.579 0.421
I67.4 Hypertensive encephalopathy
0.000 0.579 0.421
I67.3 Progressive vascular leukoencephalopathy
0.000 0.579 0.421
I62 Other nontraumatic intracranial haemorrhage
0.000 0.580 0.420
I15.9 Seconday hypertension, unspecified
0.000 0.581 0.419
I15.8 Other secondary hypertension
0.000 0.581 0.419
I15.2 Hypertension secondary to endocrine disorders
0.000 0.581 0.419
I15.0 Renovascular hypertension
0.000 0.581 0.419
I61 Intracerebral haemorrhage
0.000 0.597 0.403
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.598 0.402
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.598 0.402
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.598 0.402
I65.1 Occlusion and stenosis of basilar artery
0.000 0.598 0.402
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.598 0.402
I20.0 Unstable angina
0.000 0.599 0.401
I23.8 Other current complications following acute myocardial infarction
0.000 0.599 0.401
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.599 0.401
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.599 0.401
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.599 0.401
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.599 0.401
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.599 0.401
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.599 0.401
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.599 0.401
I02 Rheumatic chorea
0.000 0.606 0.394
I01 Rheumatic fever with heart involvement
0.000 0.606 0.394
I00 Rheumatic fever without mention of heart involvement
0.000 0.606 0.394
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.624 0.376
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.644 0.356
I09 Other rheumatic heart diseases
0.000 0.644 0.356
I06 Rheumatic aortic valve diseases
0.000 0.644 0.356
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.644 0.356
I60 Subarachnoid haemorrhage
0.000 0.644 0.355
I15.1 Hypertension secondary to other renal disorders
0.000 0.646 0.353
I05.9 Mitral valve disease, unspecified
0.000 0.649 0.350
I25.3 Aneurysm of heart
0.001 0.655 0.344
I05.0 Mitral stenosis
0.000 0.659 0.341
I07 Rheumatic tricuspid valve diseases
0.000 0.660 0.340
I22.8 Subsequent myocardial infarction of other sites
0.000 0.663 0.337
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.671 0.329
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.671 0.329
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.671 0.329
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.671 0.329
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.671 0.329
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.671 0.329
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.671 0.329
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.671 0.329
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.671 0.329
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.671 0.329
I68.0 Cerebral amyloid angiopathy
0.000 0.671 0.329
I27 Other pulmonary heart diseases
0.001 0.671 0.328
I05.2 Mitral stenosis with insufficiency
0.000 0.673 0.327
I63.8 Other cerebral infarction
0.000 0.675 0.324
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.677 0.323
I28 Other diseases of pulmonary vessels
0.001 0.684 0.315
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.685 0.315
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.688 0.312
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.689 0.311
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.689 0.311
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.689 0.311
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.690 0.310
I05.8 Other mitral valve diseases
0.000 0.696 0.304
I63.9 Cerebral infarction, unspecified
0.000 0.698 0.302
I62.1 Nontraumatic extradural haemorrhage
0.000 0.699 0.301
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.700 0.300
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.706 0.294
I95 Hypotension
0.000 0.709 0.291
I27.0 Primary pulmonary hypertension
0.000 0.709 0.291
I61.8 Other intracerebral haemorrhage
0.000 0.711 0.289
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.711 0.289
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.711 0.289
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.711 0.289
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.711 0.289
I72 Other aneurysm
0.000 0.711 0.289
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.717 0.282
I01.8 Other acute rheumatic heart disease
0.000 0.717 0.282
I01.2 Acute rheumatic myocarditis
0.000 0.717 0.282
I01.1 Acute rheumatic endocarditis
0.000 0.717 0.282
I01.0 Acute rheumatic pericarditis
0.000 0.717 0.282
I02.9 Rheumatic chorea without heart involvement
0.000 0.717 0.282
I02.0 Rheumatic chorea with heart involvement
0.000 0.717 0.282
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.719 0.281
I99 Other and unspecified disorders of circulatory system
0.000 0.723 0.277
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.728 0.272
I05.1 Rheumatic mitral insufficiency
0.000 0.729 0.271
I95.1 Orthostatic hypotension
0.000 0.731 0.269
I69 Sequelae of cerebrovascular disease
0.000 0.731 0.268
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.734 0.265
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.735 0.265
I72.4 Aneurysm of artery of lower extremity
0.000 0.740 0.260
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.743 0.257
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.744 0.256
I70 Atherosclerosis
0.000 0.744 0.256
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.745 0.255
I06.8 Other rheumatic aortic valve diseases
0.000 0.745 0.255
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.745 0.255
I06.1 Rheumatic aortic insufficiency
0.000 0.745 0.255
I06.0 Rheumatic aortic stenosis
0.000 0.745 0.255
I09.9 Rheumatic heart disease, unspecified
0.000 0.745 0.255
I09.8 Other specified rheumatic heart diseases
0.000 0.745 0.255
I09.2 Chronic rheumatic pericarditis
0.000 0.745 0.255
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.745 0.255
I09.0 Rheumatic myocarditis
0.000 0.745 0.255
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.745 0.255
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.745 0.255
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.745 0.255
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.745 0.255
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.745 0.255
I20.1 Angina pectoris with documented spasm
0.000 0.746 0.254
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.754 0.245
I07.9 Tricuspid valve disease, unspecified
0.000 0.756 0.244
I07.8 Other tricuspid valve diseases
0.000 0.756 0.244
I07.2 Tricuspid stenosis with insufficiency
0.000 0.756 0.244
I07.0 Tricuspid stenosis
0.000 0.756 0.244
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.763 0.237
I27.8 Other specified pulmonary heart diseases
0.001 0.764 0.235
I27.1 Kyphoscoliotic heart disease
0.001 0.764 0.235
I72.0 Aneurysm of carotid artery
0.000 0.765 0.235
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.767 0.233
I78 Diseases of capillaries
0.000 0.770 0.230
I97.1 Other functional disturbances following cardiac surgery
0.000 0.770 0.230
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.771 0.229
I07.1 Tricuspid insufficiency
0.000 0.771 0.228
I28.9 Disease of pulmonary vessels, unspecified
0.001 0.773 0.226
I28.8 Other specified diseases of pulmonary vessels
0.001 0.773 0.226
I28.1 Aneurysm of pulmonary artery
0.001 0.773 0.226
I28.0 Arteriovenous fistula of pulmonary vessels
0.001 0.773 0.226
I72.3 Aneurysm of iliac artery
0.000 0.777 0.223
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.784 0.215
I97.0 Postcardiotomy syndrome
0.000 0.784 0.215
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.786 0.214
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.787 0.213
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.789 0.211
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.789 0.211
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.789 0.211
I98.0 Cardiovascular syphilis
0.000 0.789 0.211
I72.8 Aneurysm of other specified arteries
0.000 0.791 0.209
I95.0 Idiopathic hypotension
0.000 0.791 0.209
I72.9 Aneurysm of unspecified site
0.000 0.792 0.207
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.792 0.207
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.792 0.207
I72.2 Aneurysm of renal artery
0.000 0.792 0.207
I72.1 Aneurysm of artery of upper extremity
0.000 0.792 0.207
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.797 0.203
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.798 0.202
I27.2 Other secondary pulmonary hypertension
0.000 0.799 0.200
I95.2 Hypotension due to drugs
0.000 0.805 0.195
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.807 0.193
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.807 0.192
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.808 0.192
I22.0 Subsequent myocardial infarction of anterior wall
0.001 0.810 0.189
I70.0 Atherosclerosis of aorta
0.000 0.810 0.190
I27.9 Pulmonary heart disease, unspecified
0.001 0.813 0.186
I70.9 Generalised and unspecified atherosclerosis
0.000 0.816 0.183
I70.8 Atherosclerosis of other arteries
0.000 0.816 0.183
I70.1 Atherosclerosis of renal artery
0.000 0.816 0.183
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.001 0.817 0.182
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.817 0.183
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.818 0.182
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.820 0.180
I26 Pulmonary embolism
0.004 0.820 0.176
I95.8 Other hypotension
0.000 0.822 0.177
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.829 0.171
I78.9 Disease of capillaries, unspecified
0.000 0.835 0.165
I78.8 Other diseases of capillaries
0.000 0.835 0.165
I08 Multiple valve diseases
0.000 0.840 0.160
I60.8 Other subarachnoid haemorrhage
0.001 0.840 0.159
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.846 0.154
I79.1 Aortitis in diseases classified elsewhere
0.000 0.846 0.154
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.846 0.154
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.847 0.153
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.001 0.847 0.152
I78.1 Naevus, nonneoplastic
0.000 0.850 0.150
I20.8 Other forms of angina pectoris
0.000 0.853 0.147
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.854 0.145
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.857 0.143
I77 Other disorders of arteries and arterioles
0.000 0.859 0.141
I20.9 Angina pectoris, unspecified
0.000 0.862 0.138
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.864 0.136
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.868 0.132
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.868 0.132
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.868 0.132
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.868 0.132
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.868 0.132
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.868 0.132
I74 Arterial embolism and thrombosis
0.000 0.870 0.130
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.003 0.875 0.122
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.876 0.124
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.884 0.116
I08.9 Multiple valve disease, unspecified
0.000 0.885 0.115
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.890 0.110
I77.8 Other specified disorders of arteries and arterioles
0.000 0.895 0.105
D47.1 Chronic myeloproliferative disease
0.102 0.898 0.000
I77.5 Necrosis of artery
0.000 0.899 0.101
I77.4 Coeliac artery compression syndrome
0.000 0.899 0.101
I77.3 Arterial fibromuscular dysplasia
0.000 0.899 0.101
I77.0 Arteriovenous fistula, acquired
0.000 0.899 0.101
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.100 0.900 0.000
I71 Aortic aneurysm and dissection
0.000 0.903 0.096
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.904 0.095
I73 Other peripheral vascular diseases
0.000 0.906 0.094
I74.8 Embolism and thrombosis of other arteries
0.000 0.906 0.093
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.906 0.093
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.906 0.093
D47.3 Essential (haemorrhagic) thrombocythaemia
0.094 0.906 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.090 0.910 0.000
I08.0 Disorders of both mitral and aortic valves
0.000 0.911 0.089
I77.2 Rupture of artery
0.000 0.911 0.088
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.087 0.913 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.915 0.085
D46 Myelodysplastic syndromes
0.084 0.916 0.000
I74.5 Embolism and thrombosis of iliac artery
0.000 0.918 0.082
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.918 0.082
D47.4 Osteomyelofibrosis
0.080 0.920 0.000
D37.4 Colon
0.080 0.920 0.000
I08.8 Other multiple valve diseases
0.001 0.921 0.078
D37.5 Rectum
0.075 0.925 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.075 0.925 0.000
D45 Polycythaemia vera
0.073 0.927 0.000
D47.2 Monoclonal gammopathy
0.073 0.927 0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.072 0.928 0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.072 0.928 0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.072 0.928 0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.072 0.928 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.072 0.928 0.000
D37.3 Appendix
0.071 0.928 0.000
D46.7 Other myelodysplastic syndromes
0.071 0.929 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.929 0.071
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.930 0.069
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.930 0.069
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.930 0.069
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.930 0.069
D37.9 Digestive organ, unspecified
0.068 0.932 0.000
D37.1 Stomach
0.067 0.932 0.000
I73.8 Other specified peripheral vascular diseases
0.000 0.933 0.067
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.933 0.067
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.934 0.066
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.935 0.065
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.065 0.935 0.000
I69.3 Sequelae of cerebral infarction
0.002 0.936 0.062
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.064 0.936 0.000
D37.2 Small intestine
0.063 0.937 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.062 0.938 0.000
I77.6 Arteritis, unspecified
0.000 0.938 0.062
I77.1 Stricture of artery
0.000 0.939 0.061
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
0.060 0.940 0.000
D46.5 Refractory anaemia with multi-lineage dysplasia
0.060 0.940 0.000
D46.4 Refractory anaemia, unspecified
0.060 0.940 0.000
D46.3 Refractory anaemia with excess of blasts with transformation
0.060 0.940 0.000
D46.2 Refractory anaemia with excess of blasts
0.060 0.940 0.000
D46.1 Refractory anaemia with sideroblasts
0.060 0.940 0.000
D46.0 Refractory anaemia without sideroblasts, so stated
0.060 0.940 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.940 0.059
D44.0 Thyroid gland
0.059 0.941 0.000
I71.0 Dissection of aorta [any part]
0.000 0.941 0.058
D37.6 Liver, gallbladder and bile ducts
0.058 0.942 0.000
D37.0 Lip, oral cavity and pharynx
0.058 0.942 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.943 0.057
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.056 0.944 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.056 0.944 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.056 0.944 0.000
D41.4 Bladder
0.053 0.947 0.000
D44.9 Endocrine gland, unspecified
0.052 0.948 0.000
D44.8 Pluriglandular involvement
0.052 0.948 0.000
D44.7 Aortic body and other paraganglia
0.052 0.948 0.000
D44.6 Carotid body
0.052 0.948 0.000
D44.5 Pineal gland
0.052 0.948 0.000
D44.4 Craniopharyngeal duct
0.052 0.948 0.000
D44.3 Pituitary gland
0.052 0.948 0.000
D44.2 Parathyroid gland
0.052 0.948 0.000
D44.1 Adrenal gland
0.052 0.948 0.000
I95.9 Hypotension, unspecified
0.000 0.948 0.052
I30-I52 Other forms of heart disease
0.000 0.948 0.052
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.051 0.949 0.000
D37.7 Other digestive organs
0.049 0.951 0.000
I42 Cardiomyopathy
0.000 0.952 0.048
D42.9 Meninges, unspecified
0.046 0.953 0.000
D42.1 Spinal meninges
0.046 0.953 0.000
D42.0 Cerebral meninges
0.046 0.953 0.000
D41.9 Urinary organ, unspecified
0.046 0.954 0.000
D41.7 Other urinary organs
0.046 0.954 0.000
D41.3 Urethra
0.046 0.954 0.000
D41.2 Ureter
0.046 0.954 0.000
D41.1 Renal pelvis
0.046 0.954 0.000
I46 Cardiac arrest
0.000 0.955 0.045
D40.9 Male genital organ, unspecified
0.045 0.955 0.000
D40.7 Other male genital organs
0.045 0.955 0.000
D40.1 Testis
0.045 0.955 0.000
D48.0 Bone and articular cartilage
0.044 0.956 0.000
I42.9 Cardiomyopathy, unspecified
0.000 0.958 0.042
D40.0 Prostate
0.042 0.958 0.000
I38 Endocarditis, valve unspecified
0.000 0.958 0.042
I49 Other cardiac arrhythmias
0.000 0.959 0.041
I33 Acute and subacute endocarditis
0.000 0.959 0.041
I46.0 Cardiac arrest with successful resuscitation
0.000 0.959 0.041
D39.9 Female genital organ, unspecified
0.040 0.959 0.000
D39.7 Other female genital organs
0.040 0.959 0.000
D39.2 Placenta
0.040 0.959 0.000
D39.0 Uterus
0.040 0.959 0.000
D38.6 Respiratory organ, unspecified
0.040 0.959 0.000
D38.5 Other respiratory organs
0.040 0.959 0.000
D38.4 Thymus
0.040 0.959 0.000
D38.3 Mediastinum
0.040 0.959 0.000
D38.2 Pleura
0.040 0.959 0.000
D38.0 Larynx
0.040 0.959 0.000
D43.9 Central nervous system, unspecified
0.040 0.960 0.000
D43.7 Other parts of central nervous system
0.040 0.960 0.000
D43.4 Spinal cord
0.040 0.960 0.000
D43.3 Cranial nerves
0.040 0.960 0.000
D43.1 Brain, infratentorial
0.040 0.960 0.000
D43.0 Brain, supratentorial
0.040 0.960 0.000
I42.0 Dilated cardiomyopathy
0.000 0.960 0.039
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.001 0.962 0.037
D48.7 Other specified sites
0.037 0.962 0.000
I45 Other conduction disorders
0.000 0.963 0.037
I52 Other heart disorders in diseases classified elsewhere
0.000 0.963 0.037
I48 Atrial fibrillation and flutter
0.000 0.963 0.037
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.963 0.037
I41 Myocarditis in diseases classified elsewhere
0.000 0.963 0.037
I40 Acute myocarditis
0.000 0.963 0.037
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.963 0.037
I32 Pericarditis in diseases classified elsewhere
0.000 0.963 0.037
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified
0.037 0.963 0.000
D48.4 Peritoneum
0.037 0.963 0.000
D48.3 Retroperitoneum
0.037 0.963 0.000
D48.2 Peripheral nerves and autonomic nervous system
0.037 0.963 0.000
I49.1 Atrial premature depolarisation
0.000 0.963 0.037
I42.2 Other hypertrophic cardiomyopathy
0.000 0.964 0.036
I42.8 Other cardiomyopathies
0.000 0.964 0.036
D48.5 Skin
0.036 0.964 0.000
I42.6 Alcoholic cardiomyopathy
0.000 0.965 0.035
I37 Pulmonary valve disorders
0.000 0.965 0.035
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.966 0.034
I42.5 Other restrictive cardiomyopathy
0.000 0.966 0.034
I42.4 Endocardial fibroelastosis
0.000 0.966 0.034
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.966 0.034
I33.0 Acute and subacute infective endocarditis
0.000 0.966 0.033
I49.0 Ventricular fibrillation and flutter
0.000 0.967 0.033
I46.1 Sudden cardiac death, so described
0.000 0.967 0.033
D41.0 Kidney
0.032 0.967 0.000
I46.9 Cardiac arrest, unspecified
0.000 0.968 0.032
I49.3 Ventricular premature depolarisation
0.000 0.968 0.032
D39.1 Ovary
0.032 0.968 0.000
D38.1 Trachea, bronchus and lung
0.031 0.968 0.000
D43.2 Brain, unspecified
0.031 0.968 0.000
I49.9 Cardiac arrhythmia, unspecified
0.000 0.968 0.032
I30 Acute pericarditis
0.000 0.969 0.031
I35 Nonrheumatic aortic valve disorders
0.000 0.969 0.031
I49.4 Other and unspecified premature depolarisation
0.000 0.969 0.031
I36 Nonrheumatic tricuspid valve disorders
0.000 0.969 0.030
I73.0 Raynaud's syndrome
0.000 0.970 0.030
I45.5 Other specified heart block
0.000 0.970 0.030
I49.2 Junctional premature depolarisation
0.000 0.970 0.030
I33.9 Acute endocarditis, unspecified
0.000 0.970 0.030
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.971 0.029
I73.9 Peripheral vascular disease, unspecified
0.000 0.972 0.028
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.028 0.972 0.000
I35.0 Aortic (valve) stenosis
0.000 0.972 0.028
Y40 Systemic antibiotics
0.028 0.972 0.000
I45.9 Conduction disorder, unspecified
0.000 0.972 0.028
D48.6 Breast
0.027 0.973 0.000
Y40.0 Penicillins
0.027 0.973 0.000
I45.4 Nonspecific intraventricular block
0.000 0.973 0.027
I45.3 Trifascicular block
0.000 0.973 0.027
I45.0 Right fascicular block
0.000 0.973 0.027
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.973 0.027
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.973 0.027
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.973 0.027
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.973 0.027
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.973 0.027
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.973 0.027
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.973 0.027
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.973 0.027
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.973 0.027
I40.9 Acute myocarditis, unspecified
0.000 0.973 0.027
I40.8 Other acute myocarditis
0.000 0.973 0.027
I40.1 Isolated myocarditis
0.000 0.973 0.027
I40.0 Infective myocarditis
0.000 0.973 0.027
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.973 0.027
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.973 0.027
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.973 0.027
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.973 0.027
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.973 0.027
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.973 0.027
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.973 0.027
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.973 0.027
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.973 0.027
I48.4 Atypical atrial flutter
0.000 0.973 0.027
I48.3 Typical atrial flutter
0.000 0.973 0.027
I48.2 Chronic atrial fibrillation
0.000 0.973 0.027
I48.1 Persistent atrial fibrillation
0.000 0.973 0.027
I48.0 Paroxysmal atrial fibrillation
0.000 0.973 0.027
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.973 0.027
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.973 0.027
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.973 0.027
I45.6 Preexcitation syndrome
0.000 0.973 0.027
I45.2 Bifascicular block
0.000 0.974 0.026
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.026 0.974 0.000
I37.9 Pulmonary valve disorder, unspecified
0.000 0.975 0.025
I37.8 Other pulmonary valve disorders
0.000 0.975 0.025
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.975 0.025
I37.0 Pulmonary valve stenosis
0.000 0.975 0.025
I45.1 Other and unspecified right bundle-branch block
0.000 0.975 0.025
Y51 Drugs primarily affecting the autonomic nervous system
0.025 0.975 0.000
I45.8 Other specified conduction disorders
0.000 0.975 0.024
Y54.3 Benzothiadiazine derivatives
0.024 0.976 0.000
Y43 Primarily systemic agents
0.023 0.977 0.000
I37.1 Pulmonary valve insufficiency
0.000 0.977 0.023
Y44 Agents primarily affecting blood constituents
0.023 0.977 0.000
D48.1 Connective and other soft tissue
0.023 0.977 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.023 0.977 0.000
Y40.9 Systemic antibiotic, unspecified
0.023 0.977 0.000
Y48 Anaesthetics and therapeutic gases
0.023 0.977 0.000
I30.8 Other forms of acute pericarditis
0.000 0.977 0.022
I30.1 Infective pericarditis
0.000 0.977 0.022
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.977 0.022
I51 Complications and ill-defined descriptions of heart disease
0.000 0.978 0.022
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.022 0.978 0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.978 0.022
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.978 0.022
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.978 0.022
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.978 0.022
Y49 Psychotropic drugs, not elsewhere classified
0.022 0.978 0.000
I31 Other diseases of pericardium
0.000 0.978 0.022
Y57 Other and unspecified drugs and medicaments
0.022 0.978 0.000
Y40.8 Other systemic antibiotics
0.022 0.978 0.000
I35.1 Aortic (valve) insufficiency
0.000 0.978 0.022
Y47 Sedatives, hypnotics and antianxiety drugs
0.021 0.979 0.000
Y59 Other and unspecified vaccines and biological substances
0.020 0.979 0.000
Y58 Bacterial vaccines
0.020 0.979 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.020 0.979 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.020 0.979 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.020 0.979 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.020 0.979 0.000
Y40.7 Antifungal antibiotics, systemically used
0.020 0.980 0.000
Y40.6 Rifamycins
0.020 0.980 0.000
Y40.5 Aminoglycosides
0.020 0.980 0.000
Y40.4 Tetracyclines
0.020 0.980 0.000
Y40.3 Macrolides
0.020 0.980 0.000
Y40.2 Chloramphenicol group
0.020 0.980 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.020 0.980 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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