TreeWAS – Variant ID: rs17093325

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	1.000	0.000	0.000
C79 Secondary malignant neoplasm of other sites	1.000	0.000	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	1.000	0.000	0.000
Chapter VIII Diseases of the ear and mastoid process	1.000	0.000	0.000
H65-H75 Diseases of middle ear and mastoid	0.999	0.001	0.000
Chapter II Neoplasms	0.999	0.001	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.998	0.002	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.997	0.003	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.996	0.004	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.994	0.006	0.000
H65 Nonsuppurative otitis media	0.993	0.007	0.000
Chapter XX External causes of morbidity and mortality	0.992	0.008	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.990	0.010	0.000
M86-M90 Other osteopathies	0.985	0.015	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.984	0.016	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.983	0.017	0.000
Y43 Primarily systemic agents	0.981	0.019	0.000
M45-M49 Spondylopathies	0.980	0.020	0.000
H90-H95 Other disorders of ear	0.980	0.020	0.000
M89 Other disorders of bone	0.979	0.021	0.000
Y43.3 Other antineoplastic drugs	0.978	0.022	0.000
M89.9 Disorder of bone, unspecified	0.976	0.024	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.974	0.026	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.974	0.026	0.000
M50-M54 Other dorsopathies	0.967	0.033	0.000
R94.5 Abnormal results of liver function studies	0.965	0.035	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.964	0.036	0.000
R50-R69 General symptoms and signs	0.963	0.037	0.000
R94 Abnormal results of function studies	0.963	0.037	0.000
R59.0 Localised enlarged lymph nodes	0.961	0.039	0.000
R59 Enlarged lymph nodes	0.961	0.039	0.000
M50 Cervical disk disorders	0.960	0.040	0.000
D70 Agranulocytosis	0.954	0.046	0.000
D73 Diseases of spleen	0.953	0.047	0.000
Chapter I Certain infectious and parasitic diseases	0.950	0.050	0.000
H90 Conductive and sensorineural hearing loss	0.948	0.052	0.000
M50.2 Other cervical disk displacement	0.947	0.053	0.000
C92 Myeloid leukaemia	0.946	0.054	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.942	0.058	0.000
R63 Symptoms and signs concerning food and fluid intake	0.942	0.058	0.000
H66 Suppurative and unspecified otitis media	0.932	0.068	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.932	0.068	0.000
M50.1 Cervical disk disorder with radiculopathy	0.924	0.076	0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.921	0.079	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.919	0.081	0.000
V10-V19 Pedal cyclist injured in transport accident	0.915	0.085	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.912	0.088	0.000
M45 Ankylosing spondylitis	0.910	0.090	0.000
M47 Spondylosis	0.910	0.090	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.910	0.090	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.909	0.091	0.000
R26 Abnormalities of gait and mobility	0.908	0.092	0.000
H92 Otalgia and effusion of ear	0.907	0.093	0.000
D73.5 Infarction of spleen	0.901	0.099	0.000
M05-M14 Inflammatory polyarthropathies	0.900	0.100	0.000
C91 Lymphoid leukaemia	0.900	0.100	0.000
R52 Pain, not elsewhere classified	0.898	0.102	0.000
D60-D64 Aplastic and other anaemias	0.897	0.103	0.000
H90.5 Sensorineural hearing loss, unspecified	0.895	0.105	0.000
D80-D89 Certain disorders involving the immune mechanism	0.894	0.106	0.000
C95 Leukaemia of unspecified cell type	0.892	0.108	0.000
C79.2 Secondary malignant neoplasm of skin	0.889	0.111	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.887	0.113	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.887	0.113	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.885	0.115	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.883	0.117	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.880	0.120	0.000
R26.2 Difficulty in walking, not elsewhere classified	0.879	0.121	0.000
R63.1 Polydipsia	0.878	0.122	0.000
R53 Malaise and fatigue	0.878	0.122	0.000
K86 Other diseases of pancreas	0.876	0.124	0.000
C80 Malignant neoplasm without specification of site	0.875	0.125	0.000
Chapter XI Diseases of the digestive system	0.875	0.125	0.000
K81.9 Cholecystitis, unspecified	0.874	0.126	0.000
H90.2 Conductive hearing loss, unspecified	0.872	0.128	0.000
K81 Cholecystitis	0.872	0.128	0.000
D72 Other disorders of white blood cells	0.869	0.131	0.000
C78.7 Secondary malignant neoplasm of liver	0.864	0.136	0.000
C92.0 Acute myeloid leukaemia	0.861	0.139	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.856	0.144	0.000
K70-K77 Diseases of liver	0.856	0.144	0.000
C81 Hodgkin's disease	0.855	0.145	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.853	0.147	0.000
R63.4 Abnormal weight loss	0.853	0.147	0.000
M53 Other dorsopathies, not elsewhere classified	0.852	0.148	0.000
M13 Other arthritis	0.848	0.152	0.000
H66.9 Otitis media, unspecified	0.848	0.152	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.843	0.157	0.000
R86 Abnormal findings in specimens from male genital organs	0.843	0.157	0.000
Chapter XXII Codes for special purposes	0.840	0.160	0.000
Y43.4 Immunosuppressive agents	0.839	0.161	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.839	0.161	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.839	0.161	0.000
D62 Acute posthaemorrhagic anaemia	0.837	0.163	0.000
H73 Other disorders of tympanic membrane	0.837	0.163	0.000
M47.9 Spondylosis, unspecified	0.835	0.165	0.000
H72 Perforation of tympanic membrane	0.834	0.166	0.000
A15-A19 Tuberculosis	0.833	0.167	0.000
K86.3 Pseudocyst of pancreas	0.833	0.167	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.833	0.167	0.000
R52.9 Pain, unspecified	0.832	0.168	0.000
M13.9 Arthritis, unspecified	0.826	0.174	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.825	0.175	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.821	0.179	0.000
X10-X19 Contact with heat and hot substances	0.818	0.182	0.000
C88 Malignant immunoproliferative diseases	0.818	0.182	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.817	0.183	0.000
Y79 Orthopaedic devices associated with adverse incidents	0.816	0.184	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.813	0.187	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.813	0.187	0.000
H65.4 Other chronic nonsuppurative otitis media	0.812	0.188	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.811	0.189	0.000
M13.98 Arthritis, unspecified (Other)	0.810	0.190	0.000
Y44 Agents primarily affecting blood constituents	0.810	0.190	0.000
H66.3 Other chronic suppurative otitis media	0.809	0.191	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.808	0.192	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.808	0.192	0.000
D73.8 Other diseases of spleen	0.806	0.194	0.000
A80-A89 Viral infections of the central nervous system	0.805	0.195	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.805	0.195	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.804	0.196	0.000
R94.2 Abnormal results of pulmonary function studies	0.804	0.196	0.000
C91.0 Acute lymphoblastic leukaemia	0.804	0.196	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.804	0.196	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.803	0.197	0.000
K72 Hepatic failure, not elsewhere classified	0.803	0.197	0.000
H74 Other disorders of middle ear and mastoid	0.801	0.199	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.800	0.200	0.000
M89.98 Disorder of bone, unspecified (Other)	0.799	0.201	0.000
C34 Malignant neoplasm of bronchus and lung	0.797	0.203	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.797	0.203	0.000
R54 Senility	0.795	0.205	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.795	0.205	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.795	0.205	0.000
H68 Eustachian salpingitis and obstruction	0.794	0.206	0.000
B95-B98 Bacterial, viral and other infectious agents	0.791	0.209	0.000
H71 Cholesteatoma of middle ear	0.791	0.209	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.789	0.211	0.000
V18.0 Driver injured in nontraffic accident	0.789	0.211	0.000
R63.3 Feeding difficulties and mismanagement	0.788	0.211	0.000
Q80-Q89 Other congenital malformations	0.786	0.214	0.000
C92.4 Acute promyelocytic leukaemia	0.783	0.216	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.783	0.217	0.000
M49 Spondylopathies in diseases classified elsewhere	0.783	0.217	0.000
X50-X57 Overexertion, travel and privation	0.782	0.218	0.000
H92.1 Otorrhoea	0.781	0.219	0.000
R93 Abnormal findings on diagnostic imaging of other body structures	0.779	0.221	0.000
C95.9 Leukaemia, unspecified	0.775	0.225	0.000
K72.9 Hepatic failure, unspecified	0.774	0.226	0.000
B91 Sequelae of poliomyelitis	0.773	0.227	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.772	0.228	0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.771	0.229	0.000
K85 Acute pancreatitis	0.771	0.229	0.000
H65.1 Other acute nonsuppurative otitis media	0.770	0.230	0.000
W50-W64 Exposure to animate mechanical forces	0.770	0.230	0.000
H92.0 Otalgia	0.769	0.231	0.000
R94.7 Abnormal results of other endocrine function studies	0.769	0.231	0.000
M47.1 Other spondylosis with myelopathy	0.768	0.232	0.000
A65-A69 Other spirochaetal diseases	0.767	0.233	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.766	0.234	0.000
K73 Chronic hepatitis, not elsewhere classified	0.766	0.234	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.765	0.235	0.000
V90-V94 Water transport accidents	0.764	0.236	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.764	0.236	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.764	0.236	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.761	0.239	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.761	0.239	0.000
K75 Other inflammatory liver diseases	0.761	0.239	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.759	0.241	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.758	0.242	0.000
A30-A49 Other bacterial diseases	0.758	0.242	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.757	0.243	0.000
V20-V29 Motorcycle rider injured in transport accident	0.750	0.250	0.000
M90 Osteopathies in diseases classified elsewhere	0.747	0.253	0.000
M70-M79 Other soft tissue disorders	0.746	0.254	0.000
D61 Other aplastic anaemias	0.746	0.254	0.000
V80-V89 Other land transport accidents	0.745	0.255	0.000
M89.3 Hypertrophy of bone	0.744	0.256	0.000
K86.9 Disease of pancreas, unspecified	0.744	0.256	0.000
M47.2 Other spondylosis with radiculopathy	0.744	0.256	0.000
D86 Sarcoidosis	0.744	0.256	0.000
Y59 Other and unspecified vaccines and biological substances	0.741	0.259	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.741	0.259	0.000
C81.9 Hodgkin's disease, unspecified	0.738	0.262	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.738	0.262	0.000
C79.6 Secondary malignant neoplasm of ovary	0.738	0.262	0.000
C84.4 Peripheral T-cell lymphoma	0.738	0.262	0.000
Y43.1 Antineoplastic antimetabolites	0.737	0.263	0.000
M48 Other spondylopathies	0.737	0.263	0.000
R84 Abnormal findings in specimens from respiratory organs and thorax	0.736	0.264	0.000
B50-B64 Protozoal diseases	0.735	0.265	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.734	0.266	0.000
M89.5 Osteolysis	0.734	0.266	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.733	0.267	0.000
R82 Other abnormal findings in urine	0.733	0.267	0.000
V95-V97 Air and space transport accidents	0.731	0.269	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.730	0.270	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.727	0.273	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.727	0.273	0.000
D72.1 Eosinophilia	0.726	0.274	0.000
R52.2 Other chronic pain	0.726	0.274	0.000
M13.94 Arthritis, unspecified (Hand)	0.725	0.275	0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.725	0.275	0.000
H65.3 Chronic mucoid otitis media	0.724	0.276	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.722	0.277	0.000
R59.1 Generalised enlarged lymph nodes	0.720	0.280	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.720	0.280	0.000
C92.9 Myeloid leukaemia, unspecified	0.718	0.281	0.000
D72.8 Other specified disorders of white blood cells	0.718	0.282	0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.718	0.282	0.000
C92.1 Chronic myeloid leukaemia	0.717	0.283	0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.717	0.283	0.000
H70 Mastoiditis and related conditions	0.717	0.283	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.716	0.283	0.000
H67 Otitis media in diseases classified elsewhere	0.716	0.283	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.715	0.284	0.000
C94 Other leukaemias of specified cell type	0.715	0.284	0.000
C86 Other specified types of T/NK-cell lymphoma	0.715	0.284	0.000
R63.5 Abnormal weight gain	0.715	0.285	0.000
C93 Monocytic leukaemia	0.715	0.285	0.000
M89.8 Other specified disorders of bone	0.714	0.286	0.000
R86.6 Abnormal cytological findings	0.714	0.286	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.714	0.286	0.000
K86.2 Cyst of pancreas	0.712	0.288	0.000
H65.0 Acute serous otitis media	0.712	0.288	0.000
Q00-Q07 Congenital malformations of the nervous system	0.712	0.288	0.000
H73.8 Other specified disorders of tympanic membrane	0.711	0.289	0.000
Y35-Y36 Legal intervention and operations of war	0.711	0.289	0.000
Y10-Y34 Event of undetermined intent	0.711	0.289	0.000
X85-X99 Assault	0.711	0.289	0.000
X30-X39 Exposure to forces of nature	0.711	0.289	0.000
W65-W74 Accidental drowning and submersion	0.711	0.289	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.711	0.289	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.711	0.289	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.711	0.289	0.000
X00-X09 Exposure to smoke, fire and flames	0.710	0.289	0.000
B99-B99 Other infectious diseases	0.710	0.290	0.000
D74 Methaemoglobinaemia	0.710	0.290	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.710	0.290	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.710	0.290	0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.710	0.290	0.000
H72.8 Other perforations of tympanic membrane	0.709	0.291	0.000
H92.2 Otorrhagia	0.709	0.291	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.707	0.293	0.000
H65.2 Chronic serous otitis media	0.707	0.293	0.000
Y43.0 Antiallergic and antiemetic drugs	0.706	0.294	0.000
Q25 Congenital malformations of great arteries	0.705	0.295	0.000
Y58 Bacterial vaccines	0.704	0.295	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.704	0.295	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.704	0.295	0.000
B35-B49 Mycoses	0.704	0.296	0.000
M00-M03 Infectious arthropathies	0.703	0.296	0.000
Y43.9 Primarily systemic agent, unspecified	0.703	0.297	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.703	0.297	0.000
Y43.6 Enzymes, not elsewhere classified	0.703	0.297	0.000
Y43.5 Acidifying and alkalising agents	0.703	0.297	0.000
Y43.2 Antineoplastic natural products	0.703	0.297	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.703	0.297	0.000
B15-B19 Viral hepatitis	0.703	0.297	0.000
C84.5 Other and unspecified T-cell lymphomas	0.703	0.297	0.000
M77 Other enthesopathies	0.703	0.297	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.702	0.298	0.000
M89.6 Osteopathy after poliomyelitis	0.702	0.298	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.702	0.298	0.000
M89.2 Other disorders of bone development and growth	0.702	0.298	0.000
M89.1 Epiphyseal arrest	0.702	0.298	0.000
K50 Crohn's disease [regional enteritis]	0.003	0.299	0.698
M89.99 Disorder of bone, unspecified (Site unspecified)	0.699	0.300	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.699	0.300	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.699	0.300	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.699	0.300	0.000
D00-D09 In situ neoplasms	0.698	0.302	0.000
R95-R99 Ill-defined and unknown causes of mortality	0.698	0.302	0.000
Y00-Y09 Assault	0.698	0.302	0.000
V40-V49 Car occupant injured in transport accident	0.697	0.302	0.000
D73.0 Hyposplenism	0.697	0.303	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.695	0.305	0.000
C91.1 Chronic lymphocytic leukaemia	0.695	0.305	0.000
R83 Abnormal findings in cerebrospinal fluid	0.694	0.305	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.694	0.306	0.000
K50.1 Crohn's disease of large intestine	0.000	0.308	0.692
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.692	0.308	0.000
M47.94 Spondylosis, unspecified (Thoracic region)	0.692	0.308	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.692	0.308	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.691	0.309	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.691	0.309	0.000
R62 Lack of expected normal physiological development	0.691	0.309	0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.690	0.310	0.000
R94.0 Abnormal results of function studies of central nervous system	0.690	0.310	0.000
Y42.7 Androgens and anabolic congeners	0.690	0.310	0.000
M12 Other specific arthropathies	0.689	0.311	0.000
M05 Seropositive rheumatoid arthritis	0.689	0.311	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.689	0.311	0.000
M53.8 Other specified dorsopathies	0.689	0.311	0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.688	0.312	0.000
V01-V09 Pedestrian injured in transport accident	0.688	0.312	0.000
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus	0.688	0.312	0.000
M87 Osteonecrosis	0.687	0.313	0.000
K76 Other diseases of liver	0.687	0.313	0.000
Y82 Other and unspecified medical devices associated with adverse incidents	0.686	0.313	0.000
Y57 Other and unspecified drugs and medicaments	0.686	0.314	0.000
V70-V79 Bus occupant injured in transport accident	0.686	0.314	0.000
K86.1 Other chronic pancreatitis	0.686	0.314	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.686	0.314	0.000
M46 Other inflammatory spondylopathies	0.685	0.314	0.000
D86.1 Sarcoidosis of lymph nodes	0.684	0.315	0.000
X58 Exposure to other specified factors	0.684	0.316	0.000
D73.9 Disease of spleen, unspecified	0.683	0.317	0.000
D73.4 Cyst of spleen	0.683	0.317	0.000
D73.3 Abscess of spleen	0.683	0.317	0.000
D73.2 Chronic congestive splenomegaly	0.683	0.317	0.000
D73.1 Hypersplenism	0.683	0.317	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.683	0.317	0.000
C34.9 Bronchus or lung, unspecified	0.683	0.317	0.000
H72.2 Other marginal perforations of tympanic membrane	0.683	0.317	0.000
X60-X84 Intentional self-harm	0.682	0.318	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.681	0.319	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.681	0.319	0.000
A75-A79 Rickettsioses	0.681	0.319	0.000
A70-A74 Other diseases caused by chlamydiae	0.681	0.319	0.000
A20-A28 Certain zoonotic bacterial diseases	0.681	0.319	0.000
M77.9 Enthesopathy, unspecified	0.680	0.320	0.000
Y44.2 Anticoagulants	0.680	0.320	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.679	0.321	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.679	0.321	0.000
C91.5 Adult T-cell leukaemia	0.678	0.322	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.678	0.322	0.000
C92.7 Other myeloid leukaemia	0.678	0.322	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.678	0.322	0.000
C92.5 Acute myelomonocytic leukaemia	0.678	0.322	0.000
C92.3 Myeloid sarcoma	0.678	0.322	0.000
C92.2 Subacute myeloid leukaemia	0.678	0.322	0.000
K85.2 Alcohol-induced acute pancreatitis	0.678	0.322	0.000
K50.9 Crohn's disease, unspecified	0.000	0.323	0.677
W75-W84 Other accidental threats to breathing	0.677	0.323	0.000
M88 Paget's disease of bone [osteitis deformans]	0.676	0.324	0.000
A41 Other septicaemia	0.676	0.324	0.000
R89 Abnormal findings in specimens from other organs, systems and tissues	0.676	0.324	0.000
R86.8 Other abnormal findings	0.675	0.324	0.000
H90.3 Sensorineural hearing loss, bilateral	0.675	0.325	0.000
R63.6 Insufficient intake of food and water due to self neglect	0.675	0.325	0.000
R63.2 Polyphagia	0.675	0.325	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.675	0.325	0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.673	0.327	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.673	0.327	0.000
K76.6 Portal hypertension	0.672	0.328	0.000
V98-V99 Other and unspecified transport accidents	0.672	0.328	0.000
R86.0 Abnormal level of enzymes	0.671	0.329	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.671	0.329	0.000
M14 Arthropathies in other diseases classified elsewhere	0.670	0.329	0.000
M65-M68 Disorders of synovium and tendon	0.670	0.330	0.000
M50.8 Other cervical disk disorders	0.670	0.330	0.000
Q28 Other congenital malformations of circulatory system	0.669	0.330	0.000
V19 Pedal cyclist injured in other and unspecified transport accidents	0.669	0.331	0.000
Y73 Gastro-enterology and urology devices associated with adverse incidents	0.669	0.331	0.000
Q27 Other congenital malformations of peripheral vascular system	0.668	0.332	0.000
V11 Pedal cyclist injured in collision with other pedal cycle	0.667	0.332	0.000
D68 Other coagulation defects	0.667	0.333	0.000
H74.4 Polyp of middle ear	0.667	0.333	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.666	0.333	0.000
C91.9 Lymphoid leukaemia, unspecified	0.666	0.334	0.000
V17 Pedal cyclist injured in collision with fixed or stationary object	0.666	0.334	0.000
D69 Purpura and other haemorrhagic conditions	0.666	0.334	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.666	0.334	0.000
R50 Fever of unknown origin	0.665	0.335	0.000
R52.0 Acute pain	0.664	0.336	0.000
Q23 Congenital malformations of aortic and mitral valves	0.663	0.337	0.000
K50.0 Crohn's disease of small intestine	0.000	0.337	0.662
H73.1 Chronic myringitis	0.662	0.338	0.000
A15 Respiratory tuberculosis, bacteriologically and histologically confirmed	0.662	0.338	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.662	0.338	0.000
U89 Agent resistant to other and unspecified antibiotics	0.661	0.339	0.000
K73.9 Chronic hepatitis, unspecified	0.660	0.340	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.660	0.340	0.000
D89.1 Cryoglobulinaemia	0.660	0.340	0.000
C77.1 Intrathoracic lymph nodes	0.660	0.340	0.000
K50.8 Other Crohn's disease	0.001	0.341	0.658
B94 Sequelae of other and unspecified infectious and parasitic diseases	0.658	0.342	0.000
M13.93 Arthritis, unspecified (Forearm)	0.658	0.342	0.000
K75.4 Autoimmune hepatitis	0.658	0.342	0.000
C34.0 Main bronchus	0.658	0.342	0.000
Q82 Other congenital malformations of skin	0.657	0.343	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.656	0.344	0.000
R64 Cachexia	0.656	0.344	0.000
V16 Pedal cyclist injured in collision with other nonmotor vehicle	0.656	0.344	0.000
V15 Pedal cyclist injured in collision with railway train or railway vehicle	0.656	0.344	0.000
V13 Pedal cyclist injured in collision with car, pick-up truck or van	0.656	0.344	0.000
V12 Pedal cyclist injured in collision with two- or three-wheeled motor vehicle	0.656	0.344	0.000
V10 Pedal cyclist injured in collision with pedestrian or animal	0.656	0.344	0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.656	0.344	0.000
Q85 Phakomatoses, not elsewhere classified	0.655	0.345	0.000
M50.3 Other cervical disk degeneration	0.655	0.345	0.000
C90.2 Plasmacytoma, extramedullary	0.655	0.345	0.000
R82.9 Other and unspecified abnormal finding in urine	0.655	0.345	0.000
C34.1 Upper lobe, bronchus or lung	0.654	0.346	0.000
V18.1 Passenger injured in nontraffic accident	0.654	0.346	0.000
M60-M63 Disorders of muscles	0.654	0.346	0.000
R94.8 Abnormal results of function studies of other organs and systems	0.653	0.347	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.653	0.347	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.653	0.347	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.653	0.347	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.653	0.347	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.653	0.347	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.653	0.347	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.653	0.347	0.000
X20-X29 Contact with venomous animals and plants	0.652	0.348	0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.652	0.348	0.000
R26.1 Paralytic gait	0.651	0.349	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.649	0.351	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.649	0.351	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.648	0.352	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.648	0.352	0.000
X10 Contact with hot drinks, food, fats and cooking oils	0.647	0.353	0.000
A81 Atypical virus infections of central nervous system	0.647	0.353	0.000
H68.1 Obstruction of Eustachian tube	0.646	0.354	0.000
H90.0 Conductive hearing loss, bilateral	0.645	0.354	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.645	0.354	0.000
M08 Juvenile arthritis	0.645	0.354	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.645	0.355	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.645	0.355	0.000
C91.7 Other lymphoid leukaemia	0.645	0.355	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.645	0.355	0.000
C91.3 Prolymphocytic leukaemia	0.645	0.355	0.000
C91.2 Subacute lymphocytic leukaemia	0.645	0.355	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.645	0.355	0.000
V53 Occupant of pick-up truck or van injured in collision with car, pick-up truck or van	0.644	0.355	0.000
D61.0 Constitutional aplastic anaemia	0.644	0.356	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.643	0.356	0.000
M13.92 Arthritis, unspecified (Upper arm)	0.643	0.356	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.643	0.357	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.641	0.359	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.641	0.359	0.000
D82 Immunodeficiency associated with other major defects	0.641	0.359	0.000
D81 Combined immunodeficiencies	0.641	0.359	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.641	0.359	0.000
H66.0 Acute suppurative otitis media	0.640	0.360	0.000
Y46.2 Hydantoin derivatives	0.640	0.360	0.000
C95.7 Other leukaemia of unspecified cell type	0.639	0.361	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.639	0.361	0.000
C95.0 Acute leukaemia of unspecified cell type	0.639	0.361	0.000
H95.1 Other disorders following mastoidectomy	0.638	0.361	0.000
A69 Other spirochaetal infections	0.636	0.364	0.000
Y81 General- and plastic-surgery devices associated with adverse incidents	0.636	0.364	0.000
Y80 Physical medicine devices associated with adverse incidents	0.636	0.364	0.000
Y78 Radiological devices associated with adverse incidents	0.636	0.364	0.000
Y75 Neurological devices associated with adverse incidents	0.636	0.364	0.000
Y74 General hospital and personal-use devices associated with adverse incidents	0.636	0.364	0.000
Y72 Otorhinolaryngological devices associated with adverse incidents	0.636	0.364	0.000
Y70 Anaesthesiology devices associated with adverse incidents	0.636	0.364	0.000
X49.9 Unspecified place	0.636	0.364	0.000
Q35-Q37 Cleft lip and cleft palate	0.636	0.364	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.636	0.364	0.000
R86.7 Abnormal histological findings	0.635	0.365	0.000
M10 Gout	0.635	0.365	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.634	0.365	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.634	0.365	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.634	0.365	0.000
C84.3 Lymphoepithelioid lymphoma	0.634	0.365	0.000
C84.2 T-zone lymphoma	0.634	0.365	0.000
C84.1 Sezary's diease	0.634	0.365	0.000
C84.0 Mycosis fungoides	0.634	0.365	0.000
R63.0 Anorexia	0.634	0.366	0.000
K85.8 Other acute pancreatitis	0.633	0.367	0.000
M86 Osteomyelitis	0.633	0.367	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.632	0.367	0.000
C81.0 Lymphocytic predominance	0.632	0.368	0.000
V18.3 Person injured while boarding or alighting	0.631	0.369	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.631	0.369	0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.630	0.370	0.000
K75.9 Inflammatory liver disease, unspecified	0.628	0.372	0.000
H72.0 Central perforation of tympanic membrane	0.628	0.372	0.000
D84 Other immunodeficiencies	0.628	0.372	0.000
M50.9 Cervical disk disorder, unspecified	0.627	0.372	0.000
X47 Accidental poisoning by and exposure to other gases and vapours	0.627	0.373	0.000
A87 Viral meningitis	0.626	0.374	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.626	0.374	0.000
C81.1 Nodular sclerosis	0.626	0.374	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.625	0.375	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.625	0.375	0.000
R81 Glycosuria	0.624	0.376	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.624	0.376	0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.623	0.377	0.000
D72.9 Disorder of white blood cells, unspecified	0.623	0.377	0.000
D72.0 Genetic anomalies of leukocytes	0.623	0.377	0.000
A16.9 Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation	0.622	0.378	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.622	0.378	0.000
Y77 Ophthalmic devices associated with adverse incidents	0.622	0.378	0.000
W20-W49 Exposure to inanimate mechanical forces	0.622	0.378	0.000
X12 Contact with other hot fluids	0.622	0.378	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.622	0.378	0.000
V80 Animal-rider or occupant of animal-drawn vehicle injured in transport accident	0.621	0.379	0.000
M53.9 Dorsopathy, unspecified	0.621	0.379	0.000
K50-K52 Noninfective enteritis and colitis	0.395	0.380	0.226
X16 Contact with hot heating appliances, radiators and pipes	0.620	0.380	0.000
B65-B83 Helminthiases	0.620	0.380	0.000
C90.0 Multiple myeloma	0.620	0.380	0.000
M71 Other bursopathies	0.619	0.380	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.619	0.381	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations