TreeWAS – Variant ID: rs17115100

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I20-I25 Ischaemic heart diseases	0.000	0.000	1.000
I20 Angina pectoris	0.000	0.000	1.000
I25 Chronic ischaemic heart disease	0.000	0.000	1.000
I20.0 Unstable angina	0.000	0.001	0.999
I10 Essential (primary) hypertension	0.000	0.013	0.987
I20.9 Angina pectoris, unspecified	0.000	0.013	0.987
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.014	0.986
I24 Other acute ischaemic heart diseases	0.000	0.023	0.977
I25.1 Atherosclerotic heart disease	0.000	0.029	0.971
I25.2 Old myocardial infarction	0.000	0.031	0.969
I10-I15 Hypertensive diseases	0.000	0.049	0.951
I21 Acute myocardial infarction	0.000	0.062	0.938
Chapter IX Diseases of the circulatory system	0.000	0.072	0.928
I22 Subsequent myocardial infarction	0.000	0.093	0.907
I21.4 Acute subendocardial myocardial infarction	0.000	0.097	0.903
I24.8 Other forms of acute ischaemic heart disease	0.000	0.107	0.893
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.115	0.885
I60-I69 Cerebrovascular diseases	0.000	0.144	0.856
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.149	0.851
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.153	0.847
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.182	0.818
I69 Sequelae of cerebrovascular disease	0.000	0.199	0.801
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.199	0.801
I20.1 Angina pectoris with documented spasm	0.000	0.209	0.791
I15 Secondary hypertension	0.000	0.215	0.785
I25.4 Coronary artery aneurysm	0.000	0.220	0.779
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.225	0.775
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.237	0.763
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.277	0.723
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.277	0.723
I22.8 Subsequent myocardial infarction of other sites	0.000	0.280	0.720
I25.6 Silent myocardial ischaemia	0.000	0.283	0.717
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.284	0.716
I25.3 Aneurysm of heart	0.000	0.297	0.703
I24.1 Dressler's syndrome	0.000	0.299	0.701
I65.2 Occlusion and stenosis of carotid artery	0.000	0.304	0.696
I13 Hypertensive heart and renal disease	0.000	0.318	0.682
I69.3 Sequelae of cerebral infarction	0.000	0.322	0.678
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.327	0.673
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.332	0.668
I25.5 Ischaemic cardiomyopathy	0.000	0.333	0.667
I15.1 Hypertension secondary to other renal disorders	0.000	0.334	0.666
I00-I02 Acute rheumatic fever	0.000	0.334	0.666
I62 Other nontraumatic intracranial haemorrhage	0.000	0.343	0.657
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.343	0.657
I23 Certain current complications following acute myocardial infarction	0.000	0.347	0.652
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.367	0.633
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.367	0.633
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.371	0.629
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.386	0.613
I60 Subarachnoid haemorrhage	0.000	0.401	0.599
I11 Hypertensive heart disease	0.000	0.401	0.599
I63 Cerebral infarction	0.000	0.405	0.595
I12 Hypertensive renal disease	0.000	0.417	0.583
I15.9 Seconday hypertension, unspecified	0.000	0.437	0.563
I15.8 Other secondary hypertension	0.000	0.437	0.563
I15.2 Hypertension secondary to endocrine disorders	0.000	0.437	0.563
I15.0 Renovascular hypertension	0.000	0.437	0.563
I67 Other cerebrovascular diseases	0.000	0.451	0.549
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.453	0.547
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.453	0.547
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.453	0.547
I65.1 Occlusion and stenosis of basilar artery	0.000	0.453	0.547
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.453	0.547
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.455	0.545
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.463	0.537
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.483	0.517
I67.1 Cerebral aneurysm, nonruptured	0.000	0.499	0.501
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.502	0.498
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.504	0.496
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.511	0.489
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.511	0.489
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.511	0.489
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.511	0.489
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.513	0.487
I02 Rheumatic chorea	0.000	0.523	0.477
I01 Rheumatic fever with heart involvement	0.000	0.523	0.477
I00 Rheumatic fever without mention of heart involvement	0.000	0.523	0.477
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.523	0.477
I62.1 Nontraumatic extradural haemorrhage	0.000	0.528	0.471
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.530	0.470
I60.8 Other subarachnoid haemorrhage	0.000	0.531	0.469
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.532	0.468
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.532	0.468
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.532	0.468
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.532	0.468
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.532	0.468
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.532	0.468
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.532	0.468
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.538	0.462
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.538	0.462
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.539	0.461
I12.9 Hypertensive renal disease without renal failure	0.000	0.542	0.457
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.543	0.457
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.560	0.440
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.560	0.440
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.560	0.440
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.560	0.440
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.560	0.440
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.560	0.440
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.560	0.440
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.570	0.429
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.570	0.429
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.570	0.429
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.570	0.429
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.570	0.429
I63.8 Other cerebral infarction	0.000	0.572	0.428
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.573	0.426
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.573	0.426
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.573	0.426
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.590	0.410
I21.9 Acute myocardial infarction, unspecified	0.000	0.592	0.408
I23.8 Other current complications following acute myocardial infarction	0.000	0.596	0.403
I67.2 Cerebral atherosclerosis	0.000	0.601	0.399
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.606	0.393
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.606	0.393
I67.5 Moyamoya disease	0.000	0.606	0.393
I67.4 Hypertensive encephalopathy	0.000	0.606	0.393
I67.3 Progressive vascular leukoencephalopathy	0.000	0.606	0.393
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.606	0.393
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.609	0.391
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.609	0.391
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.609	0.391
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.616	0.384
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.623	0.376
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.627	0.372
I99 Other and unspecified disorders of circulatory system	0.000	0.632	0.368
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.653	0.347
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.658	0.342
I01.8 Other acute rheumatic heart disease	0.000	0.658	0.342
I01.2 Acute rheumatic myocarditis	0.000	0.658	0.342
I01.1 Acute rheumatic endocarditis	0.000	0.658	0.342
I01.0 Acute rheumatic pericarditis	0.000	0.658	0.342
I02.9 Rheumatic chorea without heart involvement	0.000	0.658	0.342
I02.0 Rheumatic chorea with heart involvement	0.000	0.658	0.342
I68.0 Cerebral amyloid angiopathy	0.001	0.677	0.323
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.678	0.322
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.001	0.710	0.289
I05-I09 Chronic rheumatic heart diseases	0.000	0.712	0.288
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.724	0.276
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.731	0.268
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.751	0.249
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.751	0.249
I98.0 Cardiovascular syphilis	0.000	0.751	0.249
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.760	0.240
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.761	0.238
I12.0 Hypertensive renal disease with renal failure	0.000	0.764	0.236
I20.8 Other forms of angina pectoris	0.001	0.784	0.215
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.785	0.215
I67.8 Other specified cerebrovascular diseases	0.000	0.787	0.213
I09 Other rheumatic heart diseases	0.000	0.793	0.207
I06 Rheumatic aortic valve diseases	0.000	0.793	0.207
I67.9 Cerebrovascular disease, unspecified	0.000	0.796	0.204
I77 Other disorders of arteries and arterioles	0.000	0.804	0.196
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.807	0.192
I97.0 Postcardiotomy syndrome	0.000	0.807	0.192
I07 Rheumatic tricuspid valve diseases	0.000	0.809	0.191
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.810	0.190
I28 Other diseases of pulmonary vessels	0.001	0.818	0.181
I71 Aortic aneurysm and dissection	0.000	0.819	0.181
I77.1 Stricture of artery	0.000	0.821	0.179
I61 Intracerebral haemorrhage	0.003	0.833	0.164
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.001	0.845	0.154
I70 Atherosclerosis	0.000	0.845	0.155
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.846	0.154
I71.0 Dissection of aorta [any part]	0.000	0.848	0.152
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.851	0.148
I06.8 Other rheumatic aortic valve diseases	0.000	0.851	0.148
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.851	0.148
I06.1 Rheumatic aortic insufficiency	0.000	0.851	0.148
I06.0 Rheumatic aortic stenosis	0.000	0.851	0.148
I09.9 Rheumatic heart disease, unspecified	0.000	0.851	0.148
I09.8 Other specified rheumatic heart diseases	0.000	0.851	0.148
I09.2 Chronic rheumatic pericarditis	0.000	0.851	0.148
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.851	0.148
I09.0 Rheumatic myocarditis	0.000	0.851	0.148
I05 Rheumatic mitral valve diseases	0.000	0.852	0.148
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.856	0.144
I78 Diseases of capillaries	0.000	0.856	0.144
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.859	0.141
I77.5 Necrosis of artery	0.000	0.859	0.141
I77.4 Coeliac artery compression syndrome	0.000	0.859	0.141
I77.3 Arterial fibromuscular dysplasia	0.000	0.859	0.141
I77.2 Rupture of artery	0.000	0.859	0.141
I27 Other pulmonary heart diseases	0.001	0.860	0.140
I97.1 Other functional disturbances following cardiac surgery	0.001	0.860	0.139
I77.6 Arteritis, unspecified	0.000	0.862	0.138
I07.9 Tricuspid valve disease, unspecified	0.000	0.863	0.137
I07.8 Other tricuspid valve diseases	0.000	0.863	0.137
I07.2 Tricuspid stenosis with insufficiency	0.000	0.863	0.137
I07.0 Tricuspid stenosis	0.000	0.863	0.137
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.864	0.136
I79.1 Aortitis in diseases classified elsewhere	0.000	0.864	0.136
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.864	0.136
I28.9 Disease of pulmonary vessels, unspecified	0.001	0.870	0.130
I28.1 Aneurysm of pulmonary artery	0.001	0.870	0.130
I28.0 Arteriovenous fistula of pulmonary vessels	0.001	0.870	0.130
I63.9 Cerebral infarction, unspecified	0.000	0.870	0.130
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.870	0.130
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.870	0.130
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.870	0.130
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.870	0.130
I77.8 Other specified disorders of arteries and arterioles	0.000	0.870	0.130
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.871	0.129
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.877	0.123
I74 Arterial embolism and thrombosis	0.000	0.877	0.123
I61.5 Intracerebral haemorrhage, intraventricular	0.002	0.877	0.121
I07.1 Tricuspid insufficiency	0.000	0.878	0.121
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.002	0.878	0.119
I61.6 Intracerebral haemorrhage, multiple localised	0.002	0.880	0.118
I77.0 Arteriovenous fistula, acquired	0.000	0.881	0.119
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.881	0.119
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.002	0.886	0.111
I61.3 Intracerebral haemorrhage in brain stem	0.002	0.887	0.111
I70.9 Generalised and unspecified atherosclerosis	0.000	0.889	0.111
I70.8 Atherosclerosis of other arteries	0.000	0.889	0.111
I70.1 Atherosclerosis of renal artery	0.000	0.889	0.111
I61.8 Other intracerebral haemorrhage	0.002	0.890	0.108
I05.1 Rheumatic mitral insufficiency	0.000	0.891	0.109
I27.0 Primary pulmonary hypertension	0.000	0.892	0.108
I05.8 Other mitral valve diseases	0.000	0.893	0.106
I70.0 Atherosclerosis of aorta	0.000	0.894	0.105
I28.8 Other specified diseases of pulmonary vessels	0.001	0.896	0.103
I27.8 Other specified pulmonary heart diseases	0.000	0.896	0.103
I78.9 Disease of capillaries, unspecified	0.000	0.897	0.103
I72 Other aneurysm	0.000	0.898	0.102
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.898	0.101
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.898	0.101
I27.1 Kyphoscoliotic heart disease	0.001	0.899	0.100
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.899	0.101
I26 Pulmonary embolism	0.001	0.900	0.099
I78.8 Other diseases of capillaries	0.000	0.901	0.099
I61.4 Intracerebral haemorrhage in cerebellum	0.003	0.902	0.095
I05.9 Mitral valve disease, unspecified	0.000	0.904	0.095
I74.5 Embolism and thrombosis of iliac artery	0.000	0.905	0.095
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.907	0.093
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.909	0.091
I05.2 Mitral stenosis with insufficiency	0.001	0.911	0.089
I05.0 Mitral stenosis	0.001	0.911	0.089
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.912	0.088
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.912	0.088
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.912	0.088
I74.8 Embolism and thrombosis of other arteries	0.000	0.914	0.086
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.003	0.915	0.083
I78.1 Naevus, nonneoplastic	0.000	0.916	0.084
I27.9 Pulmonary heart disease, unspecified	0.001	0.917	0.082
Z95.2 Presence of prosthetic heart valve	0.000	0.918	0.082
I72.0 Aneurysm of carotid artery	0.000	0.918	0.082
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.920	0.080
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.920	0.080
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.920	0.080
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.920	0.080
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.920	0.080
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.920	0.080
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.923	0.077
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.924	0.076
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.927	0.073
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.927	0.073
I72.1 Aneurysm of artery of upper extremity	0.000	0.927	0.073
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.927	0.072
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.927	0.072
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.928	0.072
Z95.3 Presence of xenogenic heart valve	0.000	0.929	0.071
I72.8 Aneurysm of other specified arteries	0.000	0.929	0.070
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.930	0.070
I72.2 Aneurysm of renal artery	0.000	0.932	0.068
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.934	0.066
I08 Multiple valve diseases	0.001	0.935	0.064
I95 Hypotension	0.001	0.936	0.063
I72.9 Aneurysm of unspecified site	0.000	0.937	0.063
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.938	0.062
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.001	0.940	0.059
Z95.4 Presence of other heart-valve replacement	0.000	0.941	0.059
I72.3 Aneurysm of iliac artery	0.000	0.945	0.055
I72.4 Aneurysm of artery of lower extremity	0.000	0.948	0.051
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.949	0.051
Z95.0 Presence of cardiac pacemaker	0.000	0.949	0.051
I73 Other peripheral vascular diseases	0.000	0.953	0.047
I08.9 Multiple valve disease, unspecified	0.001	0.953	0.046
I95.8 Other hypotension	0.001	0.954	0.045
I95.0 Idiopathic hypotension	0.001	0.954	0.045
I27.2 Other secondary pulmonary hypertension	0.001	0.957	0.042
I61.9 Intracerebral haemorrhage, unspecified	0.004	0.961	0.036
I08.8 Other multiple valve diseases	0.001	0.961	0.039
I30-I52 Other forms of heart disease	0.000	0.961	0.039
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.963	0.037
I45 Other conduction disorders	0.000	0.963	0.037
I44 Atrioventricular and left bundle-branch block	0.000	0.964	0.036
I95.2 Hypotension due to drugs	0.001	0.965	0.034
I45.1 Other and unspecified right bundle-branch block	0.000	0.965	0.035
R07.4 Chest pain, unspecified	0.000	0.965	0.035
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.966	0.034
I50 Heart failure	0.000	0.966	0.034
I44.1 Atrioventricular block, second degree	0.000	0.967	0.033
I44.7 Left bundle-branch block, unspecified	0.000	0.967	0.033
F31.9 Bipolar affective disorder, unspecified	0.000	0.968	0.032
I73.8 Other specified peripheral vascular diseases	0.000	0.968	0.032
F31 Bipolar affective disorder	0.000	0.968	0.032
I50.1 Left ventricular failure	0.000	0.969	0.031
I45.2 Bifascicular block	0.000	0.969	0.031
I45.6 Preexcitation syndrome	0.000	0.970	0.030
F30-F39 Mood [affective] disorders	0.000	0.970	0.030
I45.3 Trifascicular block	0.000	0.971	0.029
I46 Cardiac arrest	0.000	0.971	0.029
I52 Other heart disorders in diseases classified elsewhere	0.000	0.972	0.028
I48 Atrial fibrillation and flutter	0.000	0.972	0.028
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.972	0.028
I41 Myocarditis in diseases classified elsewhere	0.000	0.972	0.028
I40 Acute myocarditis	0.000	0.972	0.028
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.972	0.028
I32 Pericarditis in diseases classified elsewhere	0.000	0.972	0.028
I44.0 Atrioventricular block, first degree	0.000	0.972	0.028
F32 Depressive episode	0.000	0.972	0.028
I44.6 Other and unspecified fascicular block	0.000	0.972	0.028
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.972	0.028
I45.4 Nonspecific intraventricular block	0.000	0.972	0.028
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.001	0.972	0.027
I36 Nonrheumatic tricuspid valve disorders	0.000	0.973	0.027
I45.0 Right fascicular block	0.000	0.973	0.027
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.974	0.026
I37 Pulmonary valve disorders	0.000	0.974	0.026
G40.9 Epilepsy, unspecified	0.000	0.974	0.026
I33 Acute and subacute endocarditis	0.000	0.974	0.026
I44.5 Left posterior fascicular block	0.000	0.974	0.026
I45.8 Other specified conduction disorders	0.000	0.974	0.026
F32.1 Moderate depressive episode	0.000	0.974	0.026
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.975	0.025
F33 Recurrent depressive disorder	0.000	0.975	0.025
I50.0 Congestive heart failure	0.000	0.975	0.025
G40 Epilepsy	0.000	0.975	0.025
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.976	0.024
I44.3 Other and unspecified atrioventricular block	0.000	0.976	0.024
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.976	0.024
I45.5 Other specified heart block	0.000	0.976	0.023
F41.2 Mixed anxiety and depressive disorder	0.000	0.977	0.023
Z95.1 Presence of aortocoronary bypass graft	0.000	0.977	0.023
F31.8 Other bipolar affective disorders	0.000	0.977	0.023
F31.7 Bipolar affective disorder, currently in remission	0.000	0.977	0.023
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.977	0.023
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.977	0.023
F32.0 Mild depressive episode	0.000	0.977	0.023
F40-F48 Neurotic, stress-related and somatoform disorders	0.000	0.977	0.023
F39 Unspecified mood [affective] disorder	0.000	0.977	0.023
F41 Other anxiety disorders	0.000	0.977	0.023
I46.0 Cardiac arrest with successful resuscitation	0.000	0.978	0.022
F34 Persistent mood [affective] disorders	0.000	0.978	0.022
F38 Other mood [affective] disorders	0.000	0.978	0.022
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.978	0.021
I42 Cardiomyopathy	0.000	0.978	0.022
I45.9 Conduction disorder, unspecified	0.000	0.979	0.021
Chapter V Mental and behavioural disorders	0.000	0.979	0.021
I30 Acute pericarditis	0.000	0.979	0.021
I46.1 Sudden cardiac death, so described	0.000	0.979	0.021
I31 Other diseases of pericardium	0.000	0.979	0.021
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.000	0.979	0.021
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.979	0.020
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.979	0.020
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.979	0.020
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.979	0.020
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.979	0.020
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.979	0.020
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.979	0.020
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.979	0.020
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.979	0.020
I40.9 Acute myocarditis, unspecified	0.000	0.979	0.020
I40.8 Other acute myocarditis	0.000	0.979	0.020
I40.1 Isolated myocarditis	0.000	0.979	0.020
I40.0 Infective myocarditis	0.000	0.979	0.020
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.979	0.020
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.979	0.020
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.979	0.020
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.979	0.020
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.979	0.020
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.979	0.020
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.979	0.020
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.979	0.020
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.979	0.020
I48.4 Atypical atrial flutter	0.000	0.979	0.020
I48.3 Typical atrial flutter	0.000	0.979	0.020
I48.2 Chronic atrial fibrillation	0.000	0.979	0.020
I48.1 Persistent atrial fibrillation	0.000	0.979	0.020
I48.0 Paroxysmal atrial fibrillation	0.000	0.979	0.020
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.979	0.020
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.979	0.020
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.979	0.020
F43 Reaction to severe stress, and adjustment disorders	0.000	0.979	0.020
F32.8 Other depressive episodes	0.000	0.980	0.020
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.980	0.020
F33.9 Recurrent depressive disorder, unspecified	0.000	0.980	0.020
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.980	0.020
I44.4 Left anterior fascicular block	0.000	0.980	0.020
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.980	0.020
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.980	0.020
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.980	0.020
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.980	0.020
I46.9 Cardiac arrest, unspecified	0.000	0.980	0.020
F43.1 Posttraumatic stress disorder	0.000	0.980	0.020
F30 Manic episode	0.000	0.980	0.019
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.981	0.019
F41.9 Anxiety disorder, unspecified	0.000	0.981	0.019
I44.2 Atrioventricular block, complete	0.000	0.981	0.019
I50.9 Heart failure, unspecified	0.000	0.981	0.019
I37.9 Pulmonary valve disorder, unspecified	0.000	0.981	0.019
I37.8 Other pulmonary valve disorders	0.000	0.981	0.019
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.981	0.019
I37.0 Pulmonary valve stenosis	0.000	0.981	0.019
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.981	0.019
I33.9 Acute endocarditis, unspecified	0.000	0.981	0.019
I38 Endocarditis, valve unspecified	0.000	0.981	0.019
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.981	0.019
R22.4 Localised swelling, mass and lump, lower limb	0.019	0.981	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.982	0.018
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.982	0.018
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.000	0.982	0.018
R22.1 Localised swelling, mass and lump, neck	0.018	0.982	0.000
F33.8 Other recurrent depressive disorders	0.000	0.982	0.018
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.982	0.018
F42 Obsessive-compulsive disorder	0.000	0.982	0.018
I35 Nonrheumatic aortic valve disorders	0.000	0.982	0.018
G40.8 Other epilepsy	0.000	0.982	0.018
G40.7 Petit mal, unspecified, without grand mal seizures	0.000	0.982	0.018
G40.4 Other generalised epilepsy and epileptic syndromes	0.000	0.982	0.018
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.000	0.982	0.018
F60-F69 Disorders of adult personality and behaviour	0.000	0.982	0.018
F40 Phobic anxiety disorders	0.000	0.982	0.018
F43.0 Acute stress reaction	0.000	0.982	0.018
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.018	0.982	0.000
I42.6 Alcoholic cardiomyopathy	0.000	0.983	0.017
I42.0 Dilated cardiomyopathy	0.000	0.983	0.017
F99-F99 Unspecified mental disorder	0.000	0.983	0.017
I37.1 Pulmonary valve insufficiency	0.000	0.983	0.017
G40.5 Special epileptic syndromes	0.000	0.983	0.017
I33.0 Acute and subacute infective endocarditis	0.000	0.983	0.017
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.000	0.983	0.017
F48 Other neurotic disorders	0.000	0.983	0.016
F41.8 Other specified anxiety disorders	0.000	0.983	0.016
F41.3 Other mixed anxiety disorders	0.000	0.983	0.016
F34.1 Dysthymia	0.000	0.984	0.016
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.984	0.016
F34.8 Other persistent mood [affective] disorders	0.000	0.984	0.016
F34.0 Cyclothymia	0.000	0.984	0.016
F32.9 Depressive episode, unspecified	0.000	0.984	0.016
F38.8 Other specified mood [affective] disorders	0.000	0.984	0.016
F38.1 Other recurrent mood [affective] disorders	0.000	0.984	0.016
F38.0 Other single mood [affective] disorders	0.000	0.984	0.016
F44 Dissociative [conversion] disorders	0.000	0.984	0.016
R22.0 Localised swelling, mass and lump, head	0.016	0.984	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.984	0.016
I42.5 Other restrictive cardiomyopathy	0.000	0.984	0.016
I42.4 Endocardial fibroelastosis	0.000	0.984	0.016
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.984	0.016
F60 Specific personality disorders	0.000	0.984	0.016
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.000	0.984	0.016
F30.0 Hypomania	0.000	0.985	0.015
I30.8 Other forms of acute pericarditis	0.000	0.985	0.015
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.985	0.015
I08.0 Disorders of both mitral and aortic valves	0.001	0.985	0.014
I31.8 Other specified diseases of pericardium	0.000	0.985	0.015
I31.2 Haemopericardium, not elsewhere classified	0.000	0.985	0.015
I31.1 Chronic constrictive pericarditis	0.000	0.985	0.015
I31.0 Chronic adhesive pericarditis	0.000	0.985	0.015
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.985	0.015
F43.8 Other reactions to severe stress	0.000	0.985	0.015
F80-F89 Disorders of psychological development	0.000	0.985	0.015
R22.2 Localised swelling, mass and lump, trunk	0.015	0.985	0.000
F70-F79 Mental retardation	0.000	0.985	0.015
F40.2 Specific (isolated) phobias	0.000	0.985	0.015
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.985	0.014
F10 Mental and behavioural disorders due to use of alcohol	0.000	0.985	0.015
F43.9 Reaction to severe stress, unspecified	0.000	0.985	0.014
F42.9 Obsessive-compulsive disorder, unspecified	0.000	0.985	0.014
I42.2 Other hypertrophic cardiomyopathy	0.000	0.985	0.014
F10.2 Dependence syndrome	0.000	0.986	0.014
F41.1 Generalised anxiety disorder	0.000	0.986	0.014
F99 Mental disorder, not otherwise specified	0.000	0.986	0.014
F30.8 Other manic episodes	0.000	0.986	0.014
F30.2 Mania with psychotic symptoms	0.000	0.986	0.014
F30.1 Mania without psychotic symptoms	0.000	0.986	0.014
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.000	0.986	0.014
F45 Somatoform disorders	0.000	0.986	0.014
I49 Other cardiac arrhythmias	0.000	0.986	0.014
I35.9 Aortic valve disorder, unspecified	0.000	0.986	0.014
F60.3 Emotionally unstable personality disorder	0.000	0.986	0.014
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.014	0.986	0.000
I35.1 Aortic (valve) insufficiency	0.000	0.986	0.014
I49.0 Ventricular fibrillation and flutter	0.000	0.987	0.013
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.013	0.987	0.000
I30.1 Infective pericarditis	0.000	0.987	0.013
F42.8 Other obsessive-compulsive disorders	0.000	0.987	0.013
F42.2 Mixed obsessional thoughts and acts	0.000	0.987	0.013
F42.1 Predominantly compulsive acts [obsessional rituals]	0.000	0.987	0.013
F42.0 Predominantly obsessional thoughts or ruminations	0.000	0.987	0.013
F68 Other disorders of adult personality and behaviour	0.000	0.987	0.013
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.000	0.987	0.013
F65 Disorders of sexual preference	0.000	0.987	0.013
F63 Habit and impulse disorders	0.000	0.987	0.013
F62 Enduring personality changes, not attributable to brain damage and disease	0.000	0.987	0.013
F69 Unspecified disorder of adult personality and behaviour	0.000	0.987	0.013
F61 Mixed and other personality disorders	0.000	0.987	0.013
F40.9 Phobic anxiety disorder, unspecified	0.000	0.987	0.013

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations