TreeWAS – Variant ID: rs17132883

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	0.999	0.001
Chapter I Certain infectious and parasitic diseases	0.999	0.001
A30-A49 Other bacterial diseases	0.995	0.005
Chapter II Neoplasms	0.994	0.006
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.993	0.007
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.992	0.008
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.990	0.010
S00-S09 Injuries to the head	0.990	0.010
I60-I69 Cerebrovascular diseases	0.988	0.012
A41 Other septicaemia	0.987	0.013
Chapter IX Diseases of the circulatory system	0.987	0.013
S00 Superficial injury of head	0.983	0.017
C78.0 Secondary malignant neoplasm of lung	0.980	0.020
Chapter XX External causes of morbidity and mortality	0.972	0.028
A41.9 Septicaemia, unspecified	0.969	0.031
I69 Sequelae of cerebrovascular disease	0.964	0.036
D37-D48 Neoplasms of uncertain or unknown behaviour	0.962	0.038
I67 Other cerebrovascular diseases	0.959	0.041
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.955	0.045
I67.8 Other specified cerebrovascular diseases	0.946	0.054
I63 Cerebral infarction	0.945	0.055
S00.8 Superficial injury of other parts of head	0.944	0.056
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.934	0.066
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.931	0.069
B35-B49 Mycoses	0.926	0.074
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.926	0.074
Chapter VIII Diseases of the ear and mastoid process	0.925	0.075
Y40 Systemic antibiotics	0.915	0.085
I26 Pulmonary embolism	0.899	0.101
I63.9 Cerebral infarction, unspecified	0.889	0.111
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.887	0.113
S00.9 Superficial injury of head, part unspecified	0.886	0.114
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.884	0.116
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.881	0.119
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.880	0.120
H90-H95 Other disorders of ear	0.878	0.122
B37 Candidiasis	0.873	0.127
S01 Open wound of head	0.870	0.130
Chapter XXII Codes for special purposes	0.865	0.135
Chapter V Mental and behavioural disorders	0.863	0.137
S00.0 Superficial injury of scalp	0.863	0.137
B90-B94 Sequelae of infectious and parasitic diseases	0.862	0.138
Y57 Other and unspecified drugs and medicaments	0.862	0.138
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.859	0.141
A41.5 Septicaemia due to other Gram-negative organisms	0.857	0.143
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.854	0.146
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.850	0.150
A46 Erysipelas	0.840	0.160
Y40.9 Systemic antibiotic, unspecified	0.839	0.161
A41.1 Septicaemia due to other specified staphylococcus	0.834	0.165
T15-T19 Effects of foreign body entering through natural orifice	0.830	0.170
H65-H75 Diseases of middle ear and mastoid	0.826	0.174
S06 Intracranial injury	0.825	0.175
R47-R49 Symptoms and signs involving speech and voice	0.825	0.175
C78.2 Secondary malignant neoplasm of pleura	0.822	0.178
C78.7 Secondary malignant neoplasm of liver	0.820	0.180
Y40.0 Penicillins	0.817	0.183
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.817	0.183
R91 Abnormal findings on diagnostic imaging of lung	0.817	0.183
B37.8 Candidiasis of other sites	0.816	0.184
I64 Stroke, not specified as haemorrhage or infarction	0.812	0.188
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.809	0.191
A15-A19 Tuberculosis	0.807	0.193
S09 Other and unspecified injuries of head	0.804	0.196
S01.5 Open wound of lip and oral cavity	0.804	0.196
S02 Fracture of skull and facial bones	0.803	0.197
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.802	0.198
C80 Malignant neoplasm without specification of site	0.799	0.201
I61 Intracerebral haemorrhage	0.798	0.202
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.793	0.207
Y52 Agents primarily affecting the cardiovascular system	0.793	0.207
Y51 Drugs primarily affecting the autonomic nervous system	0.788	0.212
D00-D09 In situ neoplasms	0.786	0.214
I67.0 Dissection of cerebral arteries, nonruptured	0.786	0.214
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.785	0.215
A40 Streptococcal septicaemia	0.780	0.220
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.780	0.220
I69.1 Sequelae of intracerebral haemorrhage	0.779	0.220
S00.5 Superficial injury of lip and oral cavity	0.777	0.223
S10-S19 Injuries to the neck	0.777	0.223
A48 Other bacterial diseases, not elsewhere classified	0.777	0.223
B00 Herpesviral [herpes simplex] infections	0.774	0.225
B99-B99 Other infectious diseases	0.774	0.226
R41 Other symptoms and signs involving cognitive functions and awareness	0.774	0.226
S05 Injury of eye and orbit	0.770	0.230
D37.7 Other digestive organs	0.768	0.232
T20-T25 Burns and corrosions of external body surface, specified by site	0.767	0.233
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.766	0.234
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.766	0.234
B15-B19 Viral hepatitis	0.765	0.235
B91 Sequelae of poliomyelitis	0.764	0.236
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.762	0.238
H90 Conductive and sensorineural hearing loss	0.761	0.239
Y57.9 Drug or medicament, unspecified	0.759	0.241
V01-V09 Pedestrian injured in transport accident	0.758	0.242
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.757	0.243
R47 Speech disturbances, not elsewhere classified	0.755	0.245
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.752	0.248
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.751	0.249
I69.3 Sequelae of cerebral infarction	0.751	0.249
B37.0 Candidal stomatitis	0.749	0.251
V40-V49 Car occupant injured in transport accident	0.749	0.251
Y00-Y09 Assault	0.747	0.253
H66 Suppurative and unspecified otitis media	0.746	0.254
Chapter VI Diseases of the nervous system	0.745	0.255
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.744	0.256
S00.2 Other superficial injuries of eyelid and periocular area	0.743	0.257
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.743	0.257
F00-F09 Organic, including symptomatic, mental disorders	0.737	0.263
V80-V89 Other land transport accidents	0.737	0.263
X40-X49 Accidental poisoning by and exposure to noxious substances	0.737	0.263
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.736	0.264
C78.1 Secondary malignant neoplasm of mediastinum	0.732	0.268
R41.0 Disorientation, unspecified	0.731	0.269
B65-B83 Helminthiases	0.731	0.269
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.731	0.269
D37.4 Colon	0.730	0.270
F10 Mental and behavioural disorders due to use of alcohol	0.729	0.271
D41.0 Kidney	0.728	0.272
A49 Bacterial infection of unspecified site	0.727	0.273
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.727	0.273
S90-S99 Injuries to the ankle and foot	0.726	0.274
R40 Somnolence, stupor and coma	0.726	0.274
A41.0 Septicaemia due to Staphylococcus aureus	0.725	0.275
W20-W49 Exposure to inanimate mechanical forces	0.725	0.275
H92 Otalgia and effusion of ear	0.724	0.276
Y60-Y69 Misadventures to patients during surgical and medical care	0.723	0.277
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.718	0.282
C51-C58 Malignant neoplasms of female genital organs	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.716	0.283
G35-G37 Demyelinating diseases of the central nervous system	0.717	0.283
X58-X59 Accidental exposure to other and unspecified factors	0.716	0.283
B85-B89 Pediculosis, acariasis and other infestations	0.716	0.284
B50-B64 Protozoal diseases	0.716	0.284
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.716	0.284
A75-A79 Rickettsioses	0.716	0.284
A70-A74 Other diseases caused by chlamydiae	0.716	0.284
A65-A69 Other spirochaetal diseases	0.716	0.284
A20-A28 Certain zoonotic bacterial diseases	0.716	0.284
X60-X84 Intentional self-harm	0.716	0.284
I60 Subarachnoid haemorrhage	0.715	0.285
A44 Bartonellosis	0.714	0.286
A43 Nocardiosis	0.714	0.286
A42 Actinomycosis	0.714	0.286
A39 Meningococcal infection	0.714	0.286
A37 Whooping cough	0.714	0.286
A36 Diphtheria	0.714	0.286
A32 Listeriosis	0.714	0.286
A31 Infection due to other mycobacteria	0.714	0.286
A30 Leprosy [Hansen's disease]	0.714	0.286
A38 Scarlet fever	0.714	0.286
A35 Other tetanus	0.714	0.286
A34 Obstetrical tetanus	0.714	0.286
A33 Tetanus neonatorum	0.714	0.286
D45 Polycythaemia vera	0.714	0.286
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.713	0.287
C40-C41 Malignant neoplasms of bone and articular cartilage	0.713	0.287
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.713	0.287
C76 Malignant neoplasm of other and ill-defined sites	0.712	0.288
C78.4 Secondary malignant neoplasm of small intestine	0.711	0.289
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.711	0.289
W00-W19 Falls	0.710	0.290
T33-T35 Frostbite	0.710	0.290
T26-T28 Burns and corrosions confined to eye and internal organs	0.710	0.290
T00-T07 Injuries involving multiple body regions	0.710	0.290
S08 Traumatic amputation of part of head	0.710	0.290
S07 Crushing injury of head	0.710	0.290
S04 Injury of cranial nerves	0.710	0.290
S03 Dislocation, sprain and strain of joints and ligaments of head	0.710	0.290
T66-T78 Other and unspecified effects of external causes	0.710	0.290
I68 Cerebrovascular disorders in diseases classified elsewhere	0.709	0.291
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.709	0.291
A00-A09 Intestinal infectious diseases	0.708	0.292
A41.4 Septicaemia due to anaerobes	0.708	0.292
A41.3 Septicaemia due to Haemophilus influenzae	0.708	0.292
A41.2 Septicaemia due to unspecified staphylococcus	0.708	0.292
I00-I02 Acute rheumatic fever	0.707	0.292
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.707	0.292
I63.8 Other cerebral infarction	0.705	0.295
H91 Other hearing loss	0.705	0.295
D41.4 Bladder	0.705	0.295
S00.4 Superficial injury of ear	0.704	0.295
V20-V29 Motorcycle rider injured in transport accident	0.704	0.296
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.704	0.296
Y57.5 X-ray contrast media	0.703	0.297
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.703	0.297
G35 Multiple sclerosis	0.701	0.299
B20-B24 Human immunodeficiency virus [HIV] disease	0.700	0.299
S40-S49 Injuries to the shoulder and upper arm	0.700	0.299
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.700	0.300
R45 Symptoms and signs involving emotional state	0.699	0.301
R92 Abnormal findings on diagnostic imaging of breast	0.697	0.303
Y35-Y36 Legal intervention and operations of war	0.697	0.303
Y10-Y34 Event of undetermined intent	0.697	0.303
X85-X99 Assault	0.697	0.303
X30-X39 Exposure to forces of nature	0.697	0.303
X20-X29 Contact with venomous animals and plants	0.697	0.303
X10-X19 Contact with heat and hot substances	0.697	0.303
X00-X09 Exposure to smoke, fire and flames	0.697	0.303
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.697	0.303
W75-W84 Other accidental threats to breathing	0.697	0.303
W65-W74 Accidental drowning and submersion	0.697	0.303
W50-W64 Exposure to animate mechanical forces	0.697	0.303
V98-V99 Other and unspecified transport accidents	0.697	0.303
V95-V97 Air and space transport accidents	0.697	0.303
V90-V94 Water transport accidents	0.697	0.303
V70-V79 Bus occupant injured in transport accident	0.697	0.303
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.697	0.303
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.697	0.303
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.697	0.303
S00.3 Superficial injury of nose	0.696	0.303
U80 Agent resistant to penicillin and related antibiotics	0.696	0.304
X50-X57 Overexertion, travel and privation	0.695	0.305
D37.2 Small intestine	0.694	0.306
T31 Burns classified according to extent of body surface involved	0.693	0.307
S06.6 Traumatic subarachnoid haemorrhage	0.692	0.308
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.692	0.308
R49 Voice disturbances	0.691	0.309
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.691	0.309
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.691	0.309
I69.0 Sequelae of subarachnoid haemorrhage	0.691	0.309
S00.7 Multiple superficial injuries of head	0.690	0.309
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.690	0.310
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.690	0.310
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.690	0.310
H74 Other disorders of middle ear and mastoid	0.690	0.310
B25-B34 Other viral diseases	0.689	0.311
I67.7 Cerebral arteritis, not elsewhere classified	0.688	0.312
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.688	0.312
I67.5 Moyamoya disease	0.688	0.312
I67.4 Hypertensive encephalopathy	0.688	0.312
I67.3 Progressive vascular leukoencephalopathy	0.688	0.312
R47.0 Dysphasia and aphasia	0.688	0.312
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.687	0.313
R44 Other symptoms and signs involving general sensations and perceptions	0.686	0.314
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.686	0.314
F10.0 Acute intoxication	0.686	0.314
A50-A64 Infections with a predominantly sexual mode of transmission	0.686	0.314
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.686	0.314
Y59 Other and unspecified vaccines and biological substances	0.685	0.315
Y58 Bacterial vaccines	0.685	0.315
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.685	0.315
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.685	0.315
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.685	0.315
Y53 Agents primarily affecting the gastro-intestinal system	0.685	0.315
Y50 Central nervous system stimulants, not elsewhere classified	0.685	0.315
Y49 Psychotropic drugs, not elsewhere classified	0.685	0.315
Y48 Anaesthetics and therapeutic gases	0.685	0.315
Y47 Sedatives, hypnotics and antianxiety drugs	0.685	0.315
Y46 Antiepileptics and anti-Parkinsonism drugs	0.685	0.315
Y41 Other systemic anti-infectives and antiparasitics	0.685	0.315
V10-V19 Pedal cyclist injured in transport accident	0.685	0.315
T58 Toxic effect of carbon monoxide	0.682	0.318
R42 Dizziness and giddiness	0.682	0.318
F99-F99 Unspecified mental disorder	0.678	0.322
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.678	0.322
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.678	0.322
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.678	0.322
D04 Carcinoma in situ of skin	0.676	0.323
R94 Abnormal results of function studies	0.676	0.324
R80 Isolated proteinuria	0.676	0.324
B35 Dermatophytosis	0.673	0.327
C60-C63 Malignant neoplasms of male genital organs	0.672	0.328
I61.4 Intracerebral haemorrhage in cerebellum	0.671	0.329
S01.2 Open wound of nose	0.671	0.329
D37.1 Stomach	0.671	0.329
S01.4 Open wound of cheek and temporomandibular area	0.670	0.330
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.669	0.331
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically	0.669	0.331
T17 Foreign body in respiratory tract	0.668	0.332
I05-I09 Chronic rheumatic heart diseases	0.667	0.333
S01.0 Open wound of scalp	0.665	0.335
I62 Other nontraumatic intracranial haemorrhage	0.665	0.335
B48 Other mycoses, not elsewhere classified	0.664	0.336
B47 Mycetoma	0.664	0.336
B46 Zygomycosis	0.664	0.336
B45 Cryptococcosis	0.664	0.336
B44 Aspergillosis	0.664	0.336
B43 Chromomycosis and phaeomycotic abscess	0.664	0.336
B42 Sporotrichosis	0.664	0.336
B41 Paracoccidioidomycosis	0.664	0.336
B40 Blastomycosis	0.664	0.336
B39 Histoplasmosis	0.664	0.336
B38 Coccidioidomycosis	0.664	0.336
B36 Other superficial mycoses	0.664	0.336
B49 Unspecified mycosis	0.664	0.336
I28 Other diseases of pulmonary vessels	0.664	0.336
A80-A89 Viral infections of the central nervous system	0.663	0.337
H93 Other disorders of ear, not elsewhere classified	0.662	0.338
B02 Zoster [herpes zoster]	0.662	0.338
T16 Foreign body in ear	0.661	0.339
H66.3 Other chronic suppurative otitis media	0.659	0.341
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.658	0.342
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.658	0.342
T79-T79 Certain early complications of trauma	0.658	0.342
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.657	0.342
Y40.8 Other systemic antibiotics	0.656	0.344
Y40.7 Antifungal antibiotics, systemically used	0.656	0.344
Y40.6 Rifamycins	0.656	0.344
Y40.5 Aminoglycosides	0.656	0.344
Y40.4 Tetracyclines	0.656	0.344
Y40.3 Macrolides	0.656	0.344
Y40.2 Chloramphenicol group	0.656	0.344
Y40.1 Cefalosporins and other -lactam antibiotics	0.656	0.344
H90.3 Sensorineural hearing loss, bilateral	0.655	0.345
D80-D89 Certain disorders involving the immune mechanism	0.654	0.346
B07 Viral warts	0.654	0.346
B00.1 Herpesviral vesicular dermatitis	0.653	0.347
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.651	0.349
C80.0 Malignant neoplasm, primary site unknown, so stated	0.651	0.349
R47.1 Dysarthria and anarthria	0.649	0.351
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.649	0.351
S09.8 Other specified injuries of head	0.647	0.353
F80-F89 Disorders of psychological development	0.646	0.353
C45 Mesothelioma	0.646	0.354
R40.0 Somnolence	0.646	0.354
T59 Toxic effect of other gases, fumes and vapours	0.646	0.354
C77.3 Axillary and upper limb lymph nodes	0.645	0.355
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.645	0.355
S80-S89 Injuries to the knee and lower leg	0.644	0.356
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.642	0.358
G30-G32 Other degenerative diseases of the nervous system	0.639	0.361
H92.1 Otorrhoea	0.638	0.362
I67.2 Cerebral atherosclerosis	0.638	0.362
S01.9 Open wound of head, part unspecified	0.636	0.364
D37.9 Digestive organ, unspecified	0.636	0.364
D37.6 Liver, gallbladder and bile ducts	0.636	0.364
D37.3 Appendix	0.636	0.364
D37.0 Lip, oral cavity and pharynx	0.636	0.364
F10.1 Harmful use	0.636	0.364
B06 Rubella [German measles]	0.634	0.366
B05 Measles	0.634	0.366
B01 Varicella [chickenpox]	0.634	0.366
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.634	0.366
B04 Monkeypox	0.634	0.366
B03 Smallpox	0.634	0.366
S06.4 Epidural haemorrhage	0.633	0.366
B00.9 Herpesviral infection, unspecified	0.633	0.367
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.632	0.368
R95-R99 Ill-defined and unknown causes of mortality	0.631	0.369
H94 Other disorders of ear in diseases classified elsewhere	0.630	0.370
G80-G83 Cerebral palsy and other paralytic syndromes	0.629	0.371
D07 Carcinoma in situ of other and unspecified genital organs	0.629	0.371
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.629	0.371
S70-S79 Injuries to the hip and thigh	0.628	0.372
C49 Malignant neoplasm of other connective and soft tissue	0.626	0.374
B37.7 Candidal septicaemia	0.626	0.374
B37.6 Candidal endocarditis	0.626	0.374
B37.5 Candidal meningitis	0.626	0.374
B37.4 Candidiasis of other urogenital sites	0.626	0.374
B37.2 Candidiasis of skin and nail	0.626	0.374
B37.1 Pulmonary candidiasis	0.626	0.374
S20-S29 Injuries to the thorax	0.625	0.375
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.624	0.376
S01.7 Multiple open wounds of head	0.623	0.376
S06.2 Diffuse brain injury	0.621	0.379
D50-D53 Nutritional anaemias	0.621	0.379
Y42.0 Glucocorticoids and synthetic analogs	0.621	0.379
A48.1 Legionnaires' disease	0.620	0.380
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.619	0.381
F70-F79 Mental retardation	0.619	0.381
D43.2 Brain, unspecified	0.619	0.381
S02.8 Fractures of other skull and facial bones	0.618	0.382
B94 Sequelae of other and unspecified infectious and parasitic diseases	0.618	0.382
B90 Sequelae of tuberculosis	0.618	0.382
B92 Sequelae of leprosy	0.618	0.382
Y57.8 Other drugs and medicaments	0.618	0.382
Y57.7 Vitamins, not elsewhere classified	0.618	0.382
Y57.6 Other diagnostic agents	0.618	0.382
Y57.4 Pharmaceutical excipients	0.618	0.382
Y57.3 Alcohol deterrents	0.618	0.382
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.618	0.382
Y57.1 Lipotropic drugs	0.618	0.382
Y57.0 Appetite depressants [anorectics]	0.618	0.382
H70 Mastoiditis and related conditions	0.618	0.382
D46 Myelodysplastic syndromes	0.617	0.382
F00 Dementia in Alzheimer's disease	0.617	0.383
D37.5 Rectum	0.617	0.383
A49.0 Staphylococcal infection, unspecified	0.616	0.384
R46 Symptoms and signs involving appearance and behaviour	0.616	0.384
R43 Disturbances of smell and taste	0.616	0.384
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.615	0.385
F60-F69 Disorders of adult personality and behaviour	0.614	0.386
S01.3 Open wound of ear	0.614	0.386
B99 Other and unspecified infectious diseases	0.613	0.387
S05.9 Injury of eye and orbit, part unspecified	0.612	0.388
D41.9 Urinary organ, unspecified	0.612	0.388
D41.7 Other urinary organs	0.612	0.388
D41.3 Urethra	0.612	0.388
D41.2 Ureter	0.612	0.388
D41.1 Renal pelvis	0.612	0.388
A04 Other bacterial intestinal infections	0.612	0.388
Chapter VII Diseases of the eye and adnexa	0.612	0.388
S09.9 Unspecified injury of head	0.612	0.388
Chapter XII Diseases of the skin and subcutaneous tissue	0.612	0.388
A41.8 Other specified septicaemia	0.611	0.389
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.610	0.390
H73 Other disorders of tympanic membrane	0.609	0.391
U80.1 Methicillin resistant agent	0.609	0.391
R72 Abnormality of white blood cells, not elsewhere classified	0.608	0.392
R90 Abnormal findings on diagnostic imaging of central nervous system	0.608	0.392
S02.6 Fracture of mandible	0.608	0.392
H66.9 Otitis media, unspecified	0.607	0.393
T20 Burn and corrosion of head and neck	0.607	0.393
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.606	0.394
V04 Pedestrian injured in collision with heavy transport vehicle or bus	0.605	0.394
C15-C26 Malignant neoplasms of digestive organs	0.605	0.395
S02.4 Fracture of malar and maxillary bones	0.605	0.395
S02.1 Fracture of base of skull	0.605	0.395
T31.0 Burns involving less than 10% of body surface	0.604	0.396
B37.3 Candidiasis of vulva and vagina	0.604	0.396
A40.9 Streptococcal septicaemia, unspecified	0.603	0.397
C43-C44 Melanoma and other malignant neoplasms of skin	0.601	0.399
S02.2 Fracture of nasal bones	0.600	0.400
H71 Cholesteatoma of middle ear	0.599	0.401
T18 Foreign body in alimentary tract	0.599	0.401
Y52.3 Coronary vasodilators, not elsewhere classified	0.599	0.401
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.598	0.402
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.597	0.403
R49.0 Dysphonia	0.596	0.404
T19 Foreign body in genito-urinary tract	0.595	0.405
T15 Foreign body on external eye	0.595	0.405
S00.1 Contusion of eyelid and periocular area	0.595	0.405
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.595	0.405
D09 Carcinoma in situ of other and unspecified sites	0.595	0.405
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.594	0.406
C05 Malignant neoplasm of palate	0.594	0.406
S06.8 Other intracranial injuries	0.593	0.407
S02.0 Fracture of vault of skull	0.593	0.407
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.592	0.408
H69 Other disorders of Eustachian tube	0.592	0.408
H68 Eustachian salpingitis and obstruction	0.592	0.408
H67 Otitis media in diseases classified elsewhere	0.592	0.408
S06.9 Intracranial injury, unspecified	0.592	0.408
S06.7 Intracranial injury with prolonged coma	0.592	0.408
S06.1 Traumatic cerebral oedema	0.592	0.408
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.591	0.409
W21 Striking against or struck by sports equipment	0.590	0.410
D48.6 Breast	0.590	0.410
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.590	0.410
R45.1 Restlessness and agitation	0.590	0.410
A40.8 Other streptococcal septicaemia	0.588	0.412
S06.3 Focal brain injury	0.588	0.412
C80.9 Malignant neoplasm, unspecified	0.587	0.413
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.587	0.413
T32 Corrosions classified according to extent of body surface involved	0.586	0.414
T30 Burn and corrosion, body region unspecified	0.586	0.414
T29 Burns and corrosions of multiple body regions	0.586	0.414
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.585	0.415
Y00 Assault by blunt object	0.585	0.415
B18 Chronic viral hepatitis	0.585	0.415
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.584	0.416
D51 Vitamin B12 deficiency anaemia	0.583	0.417
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.582	0.418
H91.9 Hearing loss, unspecified	0.581	0.419
T65 Toxic effect of other and unspecified substances	0.580	0.420
T63 Toxic effect of contact with venomous animals	0.580	0.420
T62 Toxic effect of other noxious substances eaten as food	0.580	0.420
T61 Toxic effect of noxious substances eaten as seafood	0.580	0.420
T60 Toxic effect of pesticides	0.580	0.420
T57 Toxic effect of other inorganic substances	0.580	0.420
T56 Toxic effect of metals	0.580	0.420
T54 Toxic effect of corrosive substances	0.580	0.420
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.580	0.420
T52 Toxic effect of organic solvents	0.580	0.420
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.580	0.420
T55 Toxic effect of soaps and detergents	0.580	0.420
Y44 Agents primarily affecting blood constituents	0.580	0.420
H74.4 Polyp of middle ear	0.580	0.420
S12 Fracture of neck	0.579	0.421
C71 Malignant neoplasm of brain	0.579	0.421
A19 Miliary tuberculosis	0.578	0.421
A18 Tuberculosis of other organs	0.578	0.421
A17 Tuberculosis of nervous system	0.578	0.421
A15 Respiratory tuberculosis, bacteriologically and histologically confirmed	0.578	0.421
I67.9 Cerebrovascular disease, unspecified	0.578	0.422
I61.5 Intracerebral haemorrhage, intraventricular	0.578	0.422
C53 Malignant neoplasm of cervix uteri	0.578	0.422
D86 Sarcoidosis	0.578	0.422
H90.2 Conductive hearing loss, unspecified	0.578	0.422
S10 Superficial injury of neck	0.578	0.422
S09.7 Multiple injuries of head	0.577	0.423
S09.2 Traumatic rupture of ear drum	0.577	0.423
S09.1 Injury of muscle and tendon of head	0.577	0.423
S09.0 Injury of blood vessels of head, not elsewhere classified	0.577	0.423
D04.3 Skin of other and unspecified parts of face	0.577	0.423
S02.9 Fracture of skull and facial bones, part unspecified	0.576	0.424
S02.7 Multiple fractures involving skull and facial bones	0.576	0.424
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.575	0.425
C46 Kaposi's sarcoma	0.575	0.425
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.575	0.425
C77.9 Lymph node, unspecified	0.574	0.426
V49 Car occupant injured in other and unspecified transport accidents	0.574	0.426
F06.7 Mild cognitive disorder	0.573	0.427
S01.1 Open wound of eyelid and periocular area	0.573	0.427
I61.8 Other intracerebral haemorrhage	0.572	0.428
I61.6 Intracerebral haemorrhage, multiple localised	0.572	0.428
I61.3 Intracerebral haemorrhage in brain stem	0.572	0.428
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.572	0.428
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.572	0.428

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations