TreeWAS – Variant ID: rs17140875

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25 Chronic ischaemic heart disease	0.087	0.913	0.000
I20 Angina pectoris	0.087	0.913	0.000
I20.9 Angina pectoris, unspecified	0.087	0.913	0.000
I20-I25 Ischaemic heart diseases	0.086	0.914	0.000
I25.1 Atherosclerotic heart disease	0.083	0.917	0.000
I22 Subsequent myocardial infarction	0.078	0.922	0.000
I25.5 Ischaemic cardiomyopathy	0.077	0.923	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.076	0.924	0.000
I20.0 Unstable angina	0.073	0.927	0.000
I20.8 Other forms of angina pectoris	0.071	0.929	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.067	0.933	0.000
I22.8 Subsequent myocardial infarction of other sites	0.064	0.935	0.000
I25.4 Coronary artery aneurysm	0.064	0.936	0.000
I25.6 Silent myocardial ischaemia	0.062	0.938	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.062	0.938	0.000
I21 Acute myocardial infarction	0.062	0.938	0.000
I23 Certain current complications following acute myocardial infarction	0.062	0.938	0.000
I25.3 Aneurysm of heart	0.060	0.940	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.060	0.940	0.000
I25.2 Old myocardial infarction	0.059	0.941	0.000
I24 Other acute ischaemic heart diseases	0.059	0.941	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.057	0.943	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.057	0.943	0.000
E66.9 Obesity, unspecified	0.054	0.946	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.053	0.947	0.000
I21.4 Acute subendocardial myocardial infarction	0.050	0.950	0.000
I20.1 Angina pectoris with documented spasm	0.048	0.952	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.047	0.953	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.045	0.955	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.045	0.955	0.000
I23.8 Other current complications following acute myocardial infarction	0.044	0.955	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.044	0.955	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.044	0.955	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.044	0.955	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.044	0.955	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.044	0.955	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.044	0.955	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.044	0.955	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.044	0.956	0.000
E66 Obesity	0.044	0.956	0.000
I21.9 Acute myocardial infarction, unspecified	0.043	0.957	0.000
I24.1 Dressler's syndrome	0.043	0.957	0.000
I24.8 Other forms of acute ischaemic heart disease	0.041	0.959	0.000
E65-E68 Obesity and other hyperalimentation	0.037	0.963	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.036	0.964	0.000
E66.0 Obesity due to excess calories	0.036	0.964	0.000
E20-E35 Disorders of other endocrine glands	0.034	0.966	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.033	0.967	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.032	0.968	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.031	0.969	0.000
E66.1 Drug-induced obesity	0.031	0.969	0.000
E21.0 Primary hyperparathyroidism	0.030	0.970	0.000
E28 Ovarian dysfunction	0.029	0.971	0.000
E21.3 Hyperparathyroidism, unspecified	0.029	0.971	0.000
E10-E14 Diabetes mellitus	0.029	0.971	0.000
E22 Hyperfunction of pituitary gland	0.028	0.972	0.000
E27 Other disorders of adrenal gland	0.027	0.973	0.000
E67 Other hyperalimentation	0.026	0.973	0.000
E68 Sequelae of hyperalimentation	0.026	0.973	0.000
E65 Localised adiposity	0.026	0.973	0.000
E34 Other endocrine disorders	0.026	0.974	0.000
E29 Testicular dysfunction	0.026	0.974	0.000
E20 Hypoparathyroidism	0.026	0.974	0.000
E10 Insulin-dependent diabetes mellitus	0.025	0.975	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.025	0.975	0.000
E32 Diseases of thymus	0.025	0.975	0.000
E31 Polyglandular dysfunction	0.025	0.975	0.000
E30 Disorders of puberty, not elsewhere classified	0.025	0.975	0.000
E25 Adrenogenital disorders	0.025	0.975	0.000
E24 Cushing's syndrome	0.025	0.975	0.000
E22.1 Hyperprolactinaemia	0.025	0.975	0.000
E23 Hypofunction and other disorders of pituitary gland	0.024	0.975	0.000
E26 Hyperaldosteronism	0.024	0.975	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.024	0.976	0.000
E28.2 Polycystic ovarian syndrome	0.024	0.976	0.000
E66.8 Other obesity	0.024	0.976	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.024	0.976	0.000
E21.4 Other specified disorders of parathyroid gland	0.024	0.976	0.000
E21.2 Other hyperparathyroidism	0.024	0.976	0.000
E14 Unspecified diabetes mellitus	0.024	0.976	0.000
E28.3 Primary ovarian failure	0.023	0.976	0.000
H81.1 Benign paroxysmal vertigo	0.023	0.977	0.000
E10.2 With renal complications	0.022	0.978	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.022	0.978	0.000
E40-E46 Malnutrition	0.022	0.978	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.022	0.978	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.022	0.978	0.000
E27.8 Other specified disorders of adrenal gland	0.022	0.978	0.000
E00-E07 Disorders of thyroid gland	0.021	0.979	0.000
E14.3 With ophthalmic complications	0.021	0.979	0.000
E13 Other specified diabetes mellitus	0.021	0.979	0.000
E28.9 Ovarian dysfunction, unspecified	0.021	0.979	0.000
E28.8 Other ovarian dysfunction	0.021	0.979	0.000
E28.1 Androgen excess	0.021	0.979	0.000
E28.0 Oestrogen excess	0.021	0.979	0.000
E10.1 With ketoacidosis	0.021	0.979	0.000
E50-E64 Other nutritional deficiencies	0.021	0.979	0.000
E10.5 With peripheral circulatory complications	0.021	0.979	0.000
E12 Malnutrition-related diabetes mellitus	0.021	0.979	0.000
E27.9 Disorder of adrenal gland, unspecified	0.021	0.979	0.000
E34.9 Endocrine disorder, unspecified	0.021	0.979	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.021	0.979	0.000
E22.8 Other hyperfunction of pituitary gland	0.021	0.979	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.021	0.979	0.000
E22.0 Acromegaly and pituitary gigantism	0.020	0.980	0.000
E23.6 Other disorders of pituitary gland	0.020	0.980	0.000
E04 Other non-toxic goitre	0.020	0.980	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.000	0.980	0.020
E10.0 With coma	0.020	0.980	0.000
E29.1 Testicular hypofunction	0.020	0.980	0.000
E20.9 Hypoparathyroidism, unspecified	0.019	0.980	0.000
E11 Non-insulin-dependent diabetes mellitus	0.020	0.980	0.000
E27.5 Adrenomedullary hyperfunction	0.019	0.980	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.019	0.980	0.000
E27.2 Addisonian crisis	0.019	0.980	0.000
E27.0 Other adrenocortical overactivity	0.019	0.980	0.000
E14.8 With unspecified complications	0.019	0.980	0.000
E67.8 Other specified hyperalimentation	0.019	0.981	0.000
E67.3 Hypervitaminosis D	0.019	0.981	0.000
E67.2 Megavitamin-B6 syndrome	0.019	0.981	0.000
E67.1 Hypercarotenaemia	0.019	0.981	0.000
E67.0 Hypervitaminosis A	0.019	0.981	0.000
E34.8 Other specified endocrine disorders	0.019	0.981	0.000
E34.5 Androgen resistance syndrome	0.019	0.981	0.000
E34.4 Constitutional tall stature	0.019	0.981	0.000
E34.3 Short stature, not elsewhere classified	0.019	0.981	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.019	0.981	0.000
E34.1 Other hypersecretion of intestinal hormones	0.019	0.981	0.000
E34.0 Carcinoid syndrome	0.019	0.981	0.000
E04.2 Non-toxic multinodular goitre	0.019	0.981	0.000
E29.9 Testicular dysfunction, unspecified	0.019	0.981	0.000
E29.8 Other testicular dysfunction	0.019	0.981	0.000
E29.0 Testicular hyperfunction	0.019	0.981	0.000
E20.8 Other hypoparathyroidism	0.019	0.981	0.000
E20.1 Pseudohypoparathyroidism	0.019	0.981	0.000
E20.0 Idiopathic hypoparathyroidism	0.019	0.981	0.000
E10.8 With unspecified complications	0.018	0.982	0.000
E10.7 With multiple complications	0.018	0.982	0.000
E10.6 With other specified complications	0.018	0.982	0.000
C15.5 Lower third of oesophagus	0.018	0.982	0.000
E10.4 With neurological complications	0.018	0.982	0.000
E25.9 Adrenogenital disorder, unspecified	0.018	0.982	0.000
E25.8 Other adrenogenital disorders	0.018	0.982	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.018	0.982	0.000
E30.9 Disorder of puberty, unspecified	0.018	0.982	0.000
E30.8 Other disorders of puberty	0.018	0.982	0.000
E30.1 Precocious puberty	0.018	0.982	0.000
E30.0 Delayed puberty	0.018	0.982	0.000
E31.9 Polyglandular dysfunction, unspecified	0.018	0.982	0.000
E31.8 Other polyglandular dysfunction	0.018	0.982	0.000
E31.1 Polyglandular hyperfunction	0.018	0.982	0.000
E31.0 Autoimmune polyglandular failure	0.018	0.982	0.000
E32.9 Disease of thymus, unspecified	0.018	0.982	0.000
E32.8 Other diseases of thymus	0.018	0.982	0.000
E32.1 Abscess of thymus	0.018	0.982	0.000
E32.0 Persistent hyperplasia of thymus	0.018	0.982	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.018	0.982	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.018	0.982	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.018	0.982	0.000
E24.8 Other Cushing's syndrome	0.018	0.982	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.018	0.982	0.000
E24.3 Ectopic ACTH syndrome	0.018	0.982	0.000
E24.2 Drug-induced Cushing's syndrome	0.018	0.982	0.000
E24.1 Nelson's syndrome	0.018	0.982	0.000
E24.0 Pituitary-dependent Cushing's disease	0.018	0.982	0.000
E24.9 Cushing's syndrome, unspecified	0.018	0.982	0.000
E23.7 Disorder of pituitary gland, unspecified	0.018	0.982	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.018	0.982	0.000
E23.1 Drug-induced hypopituitarism	0.018	0.982	0.000
E26.9 Hyperaldosteronism, unspecified	0.018	0.982	0.000
E26.8 Other hyperaldosteronism	0.018	0.982	0.000
E26.1 Secondary hyperaldosteronism	0.018	0.982	0.000
E11.2 With renal complications	0.018	0.982	0.000
E23.2 Diabetes insipidus	0.018	0.982	0.000
E26.0 Primary hyperaldosteronism	0.017	0.982	0.000
E14.7 With multiple complications	0.017	0.983	0.000
E14.6 With other specified complications	0.017	0.983	0.000
E14.5 With peripheral circulatory complications	0.017	0.983	0.000
E14.4 With neurological complications	0.017	0.983	0.000
E14.2 Withrenal complications	0.017	0.983	0.000
E14.1 With ketoacidosis	0.017	0.983	0.000
E14.0 With coma	0.017	0.983	0.000
E04.1 Non-toxic single thyroid nodule	0.017	0.983	0.000
E11.3 With ophthalmic complications	0.017	0.983	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.016	0.984	0.000
E45 Retarded development following protein-energy malnutrition	0.016	0.984	0.000
E43 Unspecified severe protein-energy malnutrition	0.016	0.984	0.000
E42 Marasmic kwashiorkor	0.016	0.984	0.000
E41 Nutritional marasmus	0.016	0.984	0.000
E40 Kwashiorkor	0.016	0.984	0.000
E15 Nondiabetic hypoglycaemic coma	0.016	0.984	0.000
E13.9 Without complications	0.016	0.984	0.000
E10.9 Without complications	0.016	0.984	0.000
E11.4 With neurological complications	0.016	0.984	0.000
E87.6 Hypokalaemia	0.000	0.984	0.016
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.016	0.984	0.000
E00 Congenital iodine-deficiency syndrome	0.016	0.984	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.016	0.984	0.000
E13.8 With unspecified complications	0.015	0.984	0.000
E13.7 With multiple complications	0.015	0.984	0.000
E13.6 With other specified complications	0.015	0.984	0.000
E13.5 With peripheral circulatory complications	0.015	0.984	0.000
E13.4 With neurological complications	0.015	0.984	0.000
E13.3 With ophthalmic complications	0.015	0.984	0.000
E13.2 With renal complications	0.015	0.984	0.000
E13.1 With ketoacidosis	0.015	0.984	0.000
E13.0 With coma	0.015	0.984	0.000
E46 Unspecified protein-energy malnutrition	0.015	0.984	0.000
C15 Malignant neoplasm of oesophagus	0.015	0.985	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.015	0.985	0.000
E63 Other nutritional deficiencies	0.015	0.985	0.000
E56 Other vitamin deficiencies	0.015	0.985	0.000
E51 Thiamine deficiency	0.015	0.985	0.000
E50 Vitamin A deficiency	0.015	0.985	0.000
E60 Dietary zinc deficiency	0.015	0.985	0.000
E59 Dietary selenium deficiency	0.015	0.985	0.000
E58 Dietary calcium deficiency	0.015	0.985	0.000
E54 Ascorbic acid deficiency	0.015	0.985	0.000
E52 Niacin deficiency [pellagra]	0.015	0.985	0.000
E12.9 Without complications	0.015	0.985	0.000
E12.8 With unspecified complications	0.015	0.985	0.000
E12.7 With multiple complications	0.015	0.985	0.000
E12.6 With other specified complications	0.015	0.985	0.000
E12.5 With peripheral circulatory complications	0.015	0.985	0.000
E12.4 With neurological complications	0.015	0.985	0.000
E12.3 With ophthalmic complications	0.015	0.985	0.000
E12.2 With renal complications	0.015	0.985	0.000
E12.1 With ketoacidosis	0.015	0.985	0.000
E12.0 With coma	0.015	0.985	0.000
E53 Deficiency of other B group vitamins	0.015	0.985	0.000
H81 Disorders of vestibular function	0.015	0.985	0.000
E16 Other disorders of pancreatic internal secretion	0.015	0.985	0.000
E55 Vitamin D deficiency	0.015	0.985	0.000
E04.8 Other specified non-toxic goitre	0.014	0.985	0.000
E04.0 Non-toxic diffuse goitre	0.014	0.985	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.014	0.985	0.000
E23.0 Hypopituitarism	0.014	0.986	0.000
E06 Thyroiditis	0.014	0.986	0.000
E11.8 With unspecified complications	0.014	0.986	0.000
E11.7 With multiple complications	0.014	0.986	0.000
E11.0 With coma	0.014	0.986	0.000
E61 Deficiency of other nutrient elements	0.014	0.986	0.000
E10.3 With ophthalmic complications	0.014	0.986	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.986	0.014
G93 Other disorders of brain	0.014	0.986	0.000
C15.4 Middle third of oesophagus	0.014	0.986	0.000
E27.1 Primary adrenocortical insufficiency	0.013	0.987	0.000
E11.1 With ketoacidosis	0.013	0.987	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.013	0.987	0.000
E07 Other disorders of thyroid	0.013	0.987	0.000
E11.6 With other specified complications	0.013	0.987	0.000
G93.9 Disorder of brain, unspecified	0.012	0.988	0.000
G93.0 Cerebral cysts	0.012	0.988	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.012	0.988	0.000
H81.9 Disorder of vestibular function, unspecified	0.012	0.988	0.000
M47.82 Other spondylosis (Cervical region)	0.012	0.988	0.000
G93.3 Postviral fatigue syndrome	0.012	0.988	0.000
E44.1 Mild protein-energy malnutrition	0.012	0.988	0.000
E44.0 Moderate protein-energy malnutrition	0.012	0.988	0.000
E87.3 Alkalosis	0.000	0.988	0.012
E11.5 With peripheral circulatory complications	0.011	0.988	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.011	0.988	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.011	0.988	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.011	0.988	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.011	0.988	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.011	0.988	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.011	0.988	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.011	0.988	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.011	0.988	0.000
G93.8 Other specified disorders of brain	0.011	0.988	0.000
G90-G99 Other disorders of the nervous system	0.011	0.989	0.000
C15.8 Overlapping lesion of oesophagus	0.011	0.989	0.000
C15.3 Upper third of oesophagus	0.011	0.989	0.000
C15.2 Abdominal part of oesophagus	0.011	0.989	0.000
C15.1 Thoracic part of oesophagus	0.011	0.989	0.000
C15.0 Cervical part of oesophagus	0.011	0.989	0.000
E50.9 Vitamin A deficiency, unspecified	0.011	0.989	0.000
E50.8 Other manifestations of vitamin A deficiency	0.011	0.989	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.011	0.989	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.011	0.989	0.000
E50.5 Vitamin A deficiency with night blindness	0.011	0.989	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.011	0.989	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.011	0.989	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.011	0.989	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.011	0.989	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.011	0.989	0.000
E51.9 Thiamine deficiency, unspecified	0.011	0.989	0.000
E51.8 Other manifestations of thiamine deficiency	0.011	0.989	0.000
E51.2 Wernicke's encephalopathy	0.011	0.989	0.000
E51.1 Beriberi	0.011	0.989	0.000
E56.9 Vitamin deficiency, unspecified	0.011	0.989	0.000
E56.8 Deficiency of other vitamins	0.011	0.989	0.000
E56.1 Deficiency of vitamin K	0.011	0.989	0.000
E56.0 Deficiency of vitamin E	0.011	0.989	0.000
E63.9 Nutritional deficiency, unspecified	0.011	0.989	0.000
E63.8 Other specified nutritional deficiencies	0.011	0.989	0.000
E63.1 Imbalance of constituents of food intake	0.011	0.989	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.011	0.989	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.011	0.989	0.000
E64.8 Sequelae of other nutritional deficiencies	0.011	0.989	0.000
E64.3 Sequelae of rickets	0.011	0.989	0.000
E64.2 Sequelae of vitamin C deficiency	0.011	0.989	0.000
E64.1 Sequelae of vitamin A deficiency	0.011	0.989	0.000
E64.0 Sequelae of protein-energy malnutrition	0.011	0.989	0.000
E53.9 Vitamin B deficiency, unspecified	0.011	0.989	0.000
E53.1 Pyridoxine deficiency	0.011	0.989	0.000
E53.0 Riboflavin deficiency	0.011	0.989	0.000
E06.9 Thyroiditis, unspecified	0.011	0.989	0.000
H81.8 Other disorders of vestibular function	0.011	0.989	0.000
H81.4 Vertigo of central origin	0.011	0.989	0.000
H81.3 Other peripheral vertigo	0.011	0.989	0.000
H81.2 Vestibular neuronitis	0.011	0.989	0.000
H81.0 Meniere's disease	0.011	0.989	0.000
C15-C26 Malignant neoplasms of digestive organs	0.011	0.989	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.011	0.989	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.011	0.989	0.000
E16.4 Abnormal secretion of gastrin	0.011	0.989	0.000
E16.3 Increased secretion of glucagon	0.011	0.989	0.000
E16.1 Other hypoglycaemia	0.011	0.989	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.011	0.989	0.000
E53.8 Deficiency of other specified B group vitamins	0.011	0.989	0.000
C15.9 Oesophagus, unspecified	0.011	0.989	0.000
C77.0 Lymph nodes of head, face and neck	0.000	0.989	0.011
E55.0 Rickets, active	0.011	0.989	0.000
G93.4 Encephalopathy, unspecified	0.011	0.989	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.011	0.989	0.000
E05.8 Other thyrotoxicosis	0.011	0.989	0.000
E05.5 Thyroid crisis or storm	0.011	0.989	0.000
E05.4 Thyrotoxicosis factitia	0.011	0.989	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.011	0.989	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.011	0.989	0.000
E03 Other hypothyroidism	0.011	0.989	0.000
E06.5 Other chronic thyroiditis	0.010	0.989	0.000
E06.4 Drug-induced thyroiditis	0.010	0.989	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.010	0.989	0.000
E06.1 Subacute thyroiditis	0.010	0.989	0.000
E06.0 Acute thyroiditis	0.010	0.989	0.000
G90 Disorders of autonomic nervous system	0.010	0.990	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.010	0.990	0.000
E61.9 Deficiency of nutrient element, unspecified	0.010	0.990	0.000
E61.8 Deficiency of other specified nutrient elements	0.010	0.990	0.000
E61.7 Deficiency of multiple nutrient elements	0.010	0.990	0.000
E61.6 Vanadium deficiency	0.010	0.990	0.000
E61.5 Molybdenum deficiency	0.010	0.990	0.000
E61.4 Chromium deficiency	0.010	0.990	0.000
E61.3 Manganese deficiency	0.010	0.990	0.000
E61.2 Magnesium deficiency	0.010	0.990	0.000
E61.0 Copper deficiency	0.010	0.990	0.000
E55.9 Vitamin D deficiency, unspecified	0.010	0.990	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.010	0.990	0.000
E14.9 Without complications	0.010	0.990	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.990	0.010
E87.4 Mixed disorder of acid-base balance	0.000	0.990	0.010
G91 Hydrocephalus	0.010	0.990	0.000
G93.7 Reye's syndrome	0.010	0.990	0.000
G93.5 Compression of brain	0.010	0.990	0.000
E16.2 Hypoglycaemia, unspecified	0.010	0.990	0.000
G93.2 Benign intracranial hypertension	0.010	0.990	0.000
E87.0 Hyperosmolality and hypernatraemia	0.000	0.990	0.010
E07.8 Other specified disorders of thyroid	0.009	0.990	0.000
E07.1 Dyshormogenetic goitre	0.009	0.990	0.000
E07.0 Hypersecretion of calcitonin	0.009	0.990	0.000
C16 Malignant neoplasm of stomach	0.010	0.990	0.000
E04.9 Non-toxic goitre, unspecified	0.009	0.990	0.000
G93.6 Cerebral oedema	0.009	0.991	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.009	0.991	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.009	0.991	0.000
E61.1 Iron deficiency	0.009	0.991	0.000
I10-I15 Hypertensive diseases	0.009	0.991	0.000
I10 Essential (primary) hypertension	0.009	0.991	0.000
G91.1 Obstructive hydrocephalus	0.009	0.991	0.000
C21 Malignant neoplasm of anus and anal canal	0.008	0.991	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.008	0.991	0.000
I05-I09 Chronic rheumatic heart diseases	0.008	0.992	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.008	0.992	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.008	0.992	0.000
G92 Toxic encephalopathy	0.008	0.992	0.000
E06.3 Autoimmune thyroiditis	0.008	0.992	0.000
Chapter IX Diseases of the circulatory system	0.008	0.992	0.000
G91.9 Hydrocephalus, unspecified	0.008	0.992	0.000
C17 Malignant neoplasm of small intestine	0.008	0.992	0.000
I08 Multiple valve diseases	0.008	0.992	0.000
G90.3 Multisystem degeneration	0.008	0.992	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.008	0.992	0.000
C23 Malignant neoplasm of gallbladder	0.008	0.992	0.000
E03.8 Other specified hypothyroidism	0.008	0.992	0.000
C16.9 Stomach, unspecified	0.008	0.992	0.000
I12 Hypertensive renal disease	0.008	0.992	0.000
E03.5 Myxoedema coma	0.008	0.992	0.000
E03.4 Atrophy of thyroid (acquired)	0.008	0.992	0.000
E03.3 Postinfectious hypothyroidism	0.008	0.992	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.008	0.992	0.000
E03.1 Congenital hypothyroidism without goitre	0.008	0.992	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.008	0.992	0.000
I05 Rheumatic mitral valve diseases	0.008	0.992	0.000
G95 Other diseases of spinal cord	0.008	0.992	0.000
G96 Other disorders of central nervous system	0.008	0.992	0.000
I12.0 Hypertensive renal disease with renal failure	0.008	0.992	0.000
H80-H83 Diseases of inner ear	0.008	0.992	0.000
M22.8 Other disorders of patella	0.008	0.992	0.000
C16.0 Cardia	0.008	0.992	0.000
B37.9 Candidiasis, unspecified	0.008	0.992	0.000
G90.8 Other disorders of autonomic nervous system	0.008	0.992	0.000
G90.4 Autonomic dysreflexia	0.008	0.992	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.008	0.992	0.000
C26.0 Intestinal tract, part unspecified	0.008	0.992	0.000
I08.0 Disorders of both mitral and aortic valves	0.008	0.992	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.008	0.992	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.007	0.992	0.000
G91.8 Other hydrocephalus	0.007	0.992	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.007	0.992	0.000
G91.2 Normal-pressure hydrocephalus	0.007	0.992	0.000
G91.0 Communicating hydrocephalus	0.007	0.992	0.000
C25 Malignant neoplasm of pancreas	0.007	0.993	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.007	0.993	0.000
C16.8 Overlapping lesion of stomach	0.007	0.993	0.000
C16.6 Greater curvature of stomach, unspecified	0.007	0.993	0.000
C16.5 Lesser curvature of stomach, unspecified	0.007	0.993	0.000
C16.4 Pylorus	0.007	0.993	0.000
C16.3 Pyloric antrum	0.007	0.993	0.000
C16.2 Body of stomach	0.007	0.993	0.000
C16.1 Fundus of stomach	0.007	0.993	0.000
I05.0 Mitral stenosis	0.007	0.993	0.000
M22 Disorders of patella	0.007	0.993	0.000
I00-I02 Acute rheumatic fever	0.007	0.993	0.000
E07.9 Disorder of thyroid, unspecified	0.007	0.993	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.007	0.993	0.000
G90.2 Horner's syndrome	0.007	0.993	0.000
E87.7 Fluid overload	0.000	0.993	0.007
G97.9 Postprocedural disorder of nervous system, unspecified	0.007	0.993	0.000
G97.8 Other postprocedural disorders of nervous system	0.007	0.993	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.007	0.993	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.007	0.993	0.000
E87.2 Acidosis	0.000	0.993	0.007
C26.9 Ill-defined sites within the digestive system	0.007	0.993	0.000
C26.8 Overlapping lesion of digestive system	0.007	0.993	0.000
C26.1 Spleen	0.007	0.993	0.000
C21.0 Anus, unspecified	0.007	0.993	0.000
C18 Malignant neoplasm of colon	0.007	0.993	0.000
I11 Hypertensive heart disease	0.007	0.993	0.000
I05.9 Mitral valve disease, unspecified	0.007	0.993	0.000
M22.4 Chondromalacia patellae	0.007	0.993	0.000
I15 Secondary hypertension	0.007	0.993	0.000
I13 Hypertensive heart and renal disease	0.007	0.993	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.007	0.993	0.000
M22.2 Patellofemoral disorders	0.007	0.993	0.000
G95.9 Disease of spinal cord, unspecified	0.006	0.994	0.000
Y52 Agents primarily affecting the cardiovascular system	0.006	0.994	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.006	0.994	0.000
C21.2 Cloacogenic zone	0.006	0.994	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.006	0.994	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.006	0.994	0.000
E05.9 Thyrotoxicosis, unspecified	0.006	0.994	0.000
I09 Other rheumatic heart diseases	0.006	0.994	0.000
I06 Rheumatic aortic valve diseases	0.006	0.994	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.006	0.994	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.006	0.994	0.000
G94.1 Hydrocephalus in neoplastic disease	0.006	0.994	0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
C17.9 Small intestine, unspecified	0.006	0.994	0.000
C21.1 Anal canal	0.006	0.994	0.000
C17.8 Overlapping lesion of small intestine	0.006	0.994	0.000
C17.3 Meckel's diverticulum	0.006	0.994	0.000
C17.2 Ileum	0.006	0.994	0.000
C17.1 Jejunum	0.006	0.994	0.000
C17.0 Duodenum	0.006	0.994	0.000
I08.8 Other multiple valve diseases	0.006	0.994	0.000
I08.9 Multiple valve disease, unspecified	0.006	0.994	0.000
C24.9 Biliary tract, unspecified	0.006	0.994	0.000
C24.8 Overlapping lesion of biliary tract	0.006	0.994	0.000
C24.1 Ampulla of Vater	0.006	0.994	0.000
C24.0 Extrahepatic bile duct	0.006	0.994	0.000
I00 Rheumatic fever without mention of heart involvement	0.006	0.994	0.000
C18.2 Ascending colon	0.006	0.994	0.000
G95.2 Cord compression, unspecified	0.006	0.994	0.000
I05.8 Other mitral valve diseases	0.006	0.994	0.000
I05.2 Mitral stenosis with insufficiency	0.006	0.994	0.000
I05.1 Rheumatic mitral insufficiency	0.006	0.994	0.000
G95.0 Syringomyelia and syringobulbia	0.006	0.994	0.000
G96.9 Disorder of central nervous system, unspecified	0.006	0.994	0.000
G96.8 Other specified disorders of central nervous system	0.006	0.994	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.006	0.994	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.006	0.994	0.000
C18.6 Descending colon	0.006	0.994	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.006	0.994	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.006	0.994	0.000
C25.9 Pancreas, unspecified	0.006	0.994	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.006	0.994	0.000
M47.8 Other spondylosis	0.006	0.994	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.005	0.994	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.006	0.994	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.005	0.994	0.000
H80 Otosclerosis	0.005	0.994	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.005	0.994	0.000
C25.8 Overlapping lesion of pancreas	0.005	0.994	0.000
C25.7 Other parts of pancreas	0.005	0.994	0.000
C25.4 Endocrine pancreas	0.005	0.994	0.000
C25.3 Pancreatic duct	0.005	0.994	0.000
C25.2 Tail of pancreas	0.005	0.994	0.000
C25.1 Body of pancreas	0.005	0.994	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations