TreeWAS – Variant ID: rs17199474

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
E10.9 Without complications	0.000	0.016	0.984
E10 Insulin-dependent diabetes mellitus	0.000	0.029	0.971
E10.3 With ophthalmic complications	0.000	0.083	0.917
K90 Intestinal malabsorption	0.000	0.095	0.905
E10-E14 Diabetes mellitus	0.000	0.152	0.848
K90-K93 Other diseases of the digestive system	0.000	0.165	0.835
K92 Other diseases of digestive system	0.000	0.178	0.822
K92.1 Melaena	0.000	0.188	0.812
E10.1 With ketoacidosis	0.000	0.191	0.809
E11 Non-insulin-dependent diabetes mellitus	0.000	0.233	0.767
E10.2 With renal complications	0.000	0.251	0.749
K92.2 Gastro-intestinal haemorrhage, unspecified	0.000	0.255	0.745
E10.5 With peripheral circulatory complications	0.000	0.257	0.743
E10.4 With neurological complications	0.000	0.278	0.722
E11.4 With neurological complications	0.000	0.296	0.704
K90.9 Intestinal malabsorption, unspecified	0.000	0.299	0.701
E03 Other hypothyroidism	0.688	0.302	0.010
E10.8 With unspecified complications	0.000	0.303	0.696
E10.7 With multiple complications	0.000	0.303	0.696
E10.6 With other specified complications	0.000	0.303	0.696
E10.0 With coma	0.000	0.303	0.696
E13 Other specified diabetes mellitus	0.000	0.325	0.675
E11.3 With ophthalmic complications	0.000	0.334	0.666
E14 Unspecified diabetes mellitus	0.000	0.335	0.665
E11.1 With ketoacidosis	0.000	0.351	0.649
K90.8 Other intestinal malabsorption	0.000	0.351	0.649
K90.3 Pancreatic steatorrhoea	0.000	0.351	0.649
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.351	0.649
K90.1 Tropical sprue	0.000	0.351	0.649
E11.5 With peripheral circulatory complications	0.000	0.362	0.638
E12 Malnutrition-related diabetes mellitus	0.000	0.392	0.608
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.401	0.599
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.408	0.592
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.409	0.591
E14.3 With ophthalmic complications	0.000	0.429	0.571
K92.9 Disease of digestive system, unspecified	0.000	0.441	0.558
E13.9 Without complications	0.000	0.449	0.551
E11.7 With multiple complications	0.000	0.450	0.550
K92.8 Other specified diseases of digestive system	0.000	0.455	0.545
E11.8 With unspecified complications	0.000	0.458	0.542
K91.3 Postoperative intestinal obstruction	0.000	0.463	0.537
E00-E07 Disorders of thyroid gland	0.513	0.467	0.021
E11.2 With renal complications	0.000	0.486	0.514
E11.0 With coma	0.000	0.487	0.513
E03.5 Myxoedema coma	0.493	0.499	0.007
E03.4 Atrophy of thyroid (acquired)	0.493	0.499	0.007
E03.3 Postinfectious hypothyroidism	0.493	0.499	0.007
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.493	0.499	0.007
E03.1 Congenital hypothyroidism without goitre	0.493	0.499	0.007
E03.0 Congenital hypothyroidism with diffuse goitre	0.493	0.499	0.007
E11.6 With other specified complications	0.000	0.507	0.492
E13.8 With unspecified complications	0.000	0.516	0.484
E13.7 With multiple complications	0.000	0.516	0.484
E13.6 With other specified complications	0.000	0.516	0.484
E13.5 With peripheral circulatory complications	0.000	0.516	0.484
E13.4 With neurological complications	0.000	0.516	0.484
E13.3 With ophthalmic complications	0.000	0.516	0.484
E13.2 With renal complications	0.000	0.516	0.484
E13.1 With ketoacidosis	0.000	0.516	0.484
E13.0 With coma	0.000	0.516	0.484
E14.8 With unspecified complications	0.000	0.523	0.477
E14.7 With multiple complications	0.000	0.523	0.477
E14.6 With other specified complications	0.000	0.523	0.477
E14.5 With peripheral circulatory complications	0.000	0.523	0.477
E14.4 With neurological complications	0.000	0.523	0.477
E14.2 Withrenal complications	0.000	0.523	0.477
E14.1 With ketoacidosis	0.000	0.523	0.477
E14.0 With coma	0.000	0.523	0.477
K91.4 Colostomy and enterostomy malfunction	0.000	0.539	0.461
E03.8 Other specified hypothyroidism	0.440	0.552	0.008
E06 Thyroiditis	0.432	0.558	0.010
E07 Other disorders of thyroid	0.429	0.560	0.011
E12.9 Without complications	0.000	0.564	0.436
E12.8 With unspecified complications	0.000	0.564	0.436
E12.7 With multiple complications	0.000	0.564	0.436
E12.6 With other specified complications	0.000	0.564	0.436
E12.5 With peripheral circulatory complications	0.000	0.564	0.436
E12.4 With neurological complications	0.000	0.564	0.436
E12.3 With ophthalmic complications	0.000	0.564	0.436
E12.2 With renal complications	0.000	0.564	0.436
E12.1 With ketoacidosis	0.000	0.564	0.436
E12.0 With coma	0.000	0.564	0.436
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.571	0.429
K93.1 Megacolon in Chagas' disease	0.000	0.571	0.429
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.571	0.429
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.576	0.424
K91.5 Postcholecystectomy syndrome	0.000	0.576	0.424
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.576	0.424
E14.9 Without complications	0.000	0.598	0.402
E05 Thyrotoxicosis [hyperthyroidism]	0.390	0.599	0.011
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.613	0.387
Chapter IV Endocrine, nutritional and metabolic diseases	0.032	0.616	0.352
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.368	0.618	0.015
E00 Congenital iodine-deficiency syndrome	0.368	0.618	0.015
E02 Subclinical iodine-deficiency hypothyroidism	0.368	0.618	0.015
E07.9 Disorder of thyroid, unspecified	0.369	0.627	0.004
E06.9 Thyroiditis, unspecified	0.356	0.639	0.006
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.018	0.641	0.341
E05.9 Thyrotoxicosis, unspecified	0.349	0.650	0.001
K91.1 Postgastric surgery syndromes	0.000	0.653	0.346
E06.3 Autoimmune thyroiditis	0.338	0.656	0.005
E16 Other disorders of pancreatic internal secretion	0.008	0.657	0.335
K92.0 Haematemesis	0.000	0.666	0.334
E16.2 Hypoglycaemia, unspecified	0.001	0.668	0.331
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.000	0.672	0.328
O48 Prolonged pregnancy	0.000	0.677	0.323
E06.5 Other chronic thyroiditis	0.309	0.683	0.007
E06.4 Drug-induced thyroiditis	0.309	0.683	0.007
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.309	0.683	0.007
E06.1 Subacute thyroiditis	0.309	0.683	0.007
E06.0 Acute thyroiditis	0.309	0.683	0.007
E07.8 Other specified disorders of thyroid	0.307	0.685	0.008
E07.1 Dyshormogenetic goitre	0.307	0.685	0.008
E07.0 Hypersecretion of calcitonin	0.307	0.685	0.008
E04 Other non-toxic goitre	0.308	0.686	0.006
O46 Antepartum haemorrhage, not elsewhere classified	0.000	0.695	0.305
O42 Premature rupture of membranes	0.000	0.696	0.304
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.285	0.708	0.007
O46.9 Antepartum haemorrhage, unspecified	0.000	0.711	0.289
E05.8 Other thyrotoxicosis	0.280	0.713	0.008
E05.5 Thyroid crisis or storm	0.280	0.713	0.008
E05.4 Thyrotoxicosis factitia	0.280	0.713	0.008
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.280	0.713	0.008
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.280	0.713	0.008
O47 False labour	0.000	0.714	0.286
E50-E64 Other nutritional deficiencies	0.022	0.716	0.262
O32 Maternal care for known or suspected malpresentation of foetus	0.000	0.725	0.275
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.264	0.726	0.011
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.264	0.726	0.011
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.264	0.726	0.011
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.264	0.726	0.011
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.264	0.726	0.011
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.264	0.726	0.011
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.264	0.726	0.011
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.264	0.726	0.011
O60-O75 Complications of labour and delivery	0.000	0.726	0.274
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.729	0.271
E40-E46 Malnutrition	0.022	0.733	0.245
Chapter XV Pregnancy, childbirth and the puerperium	0.000	0.733	0.267
O63 Long labour	0.000	0.734	0.266
O34 Maternal care for known or suspected abnormality of pelvic organs	0.000	0.734	0.266
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.737	0.263
E15 Nondiabetic hypoglycaemic coma	0.013	0.742	0.245
O69 Labour and delivery complicated by umbilical cord complications	0.000	0.743	0.257
O63.1 Prolonged second stage (of labour)	0.000	0.745	0.255
O44 Placenta praevia	0.000	0.746	0.254
O72 Postpartum haemorrhage	0.000	0.746	0.254
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.750	0.250
O43 Placental disorders	0.000	0.752	0.248
E16.9 Disorder of pancreatic internal secretion, unspecified	0.006	0.754	0.240
E16.8 Other specified disorders of pancreatic internal secretion	0.006	0.754	0.240
E16.4 Abnormal secretion of gastrin	0.006	0.754	0.240
E16.3 Increased secretion of glucagon	0.006	0.754	0.240
E16.1 Other hypoglycaemia	0.006	0.754	0.240
E16.0 Drug-induced hypoglycaemia without coma	0.006	0.754	0.240
E20-E35 Disorders of other endocrine glands	0.010	0.754	0.235
O30 Multiple gestation	0.000	0.758	0.242
O69.2 Labour and delivery complicated by other cord entanglement	0.000	0.760	0.240
O40 Polyhydramnios	0.000	0.761	0.239
O63.9 Long labour, unspecified	0.000	0.761	0.239
O45 Premature separation of placenta [abruptio placentae]	0.000	0.765	0.235
O33 Maternal care for known or suspected disproportion	0.000	0.765	0.235
O31 Complications specific to multiple gestation	0.000	0.765	0.235
O42.9 Premature rupture of membranes, unspecified	0.000	0.765	0.235
E55 Vitamin D deficiency	0.012	0.768	0.221
O32.0 Maternal care for unstable lie	0.000	0.771	0.229
O72.1 Other immediate postpartum haemorrhage	0.000	0.771	0.229
O68 Labour and delivery complicated by foetal stress [distress]	0.000	0.771	0.229
O94-O99 Other obstetric conditions, not elsewhere classified	0.000	0.772	0.228
E04.8 Other specified non-toxic goitre	0.221	0.774	0.004
E04.0 Non-toxic diffuse goitre	0.221	0.774	0.004
O64 Obstructed labour due to malposition and malpresentation of foetus	0.000	0.776	0.224
O32.1 Maternal care for breech presentation	0.000	0.778	0.222
E04.9 Non-toxic goitre, unspecified	0.217	0.780	0.003
O46.8 Other antepartum haemorrhage	0.000	0.781	0.219
O46.0 Antepartum haemorrhage with coagulation defect	0.000	0.781	0.219
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.782	0.218
I21.9 Acute myocardial infarction, unspecified	0.216	0.784	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.785	0.215
O35 Maternal care for known or suspected foetal abnormality and damage	0.000	0.786	0.214
O72.0 Third-stage haemorrhage	0.000	0.786	0.213
E53 Deficiency of other B group vitamins	0.011	0.788	0.201
O44.1 Placenta praevia with haemorrhage	0.000	0.790	0.210
O36 Maternal care for other known or suspected foetal problems	0.000	0.791	0.209
O34.1 Maternal care for tumour of corpus uteri	0.000	0.792	0.208
O66 Other obstructed labour	0.000	0.793	0.206
E64 Sequelae of malnutrition and other nutritional deficiencies	0.016	0.796	0.188
E63 Other nutritional deficiencies	0.016	0.796	0.188
E56 Other vitamin deficiencies	0.016	0.796	0.188
E51 Thiamine deficiency	0.016	0.796	0.188
E50 Vitamin A deficiency	0.016	0.796	0.188
E60 Dietary zinc deficiency	0.016	0.796	0.188
E59 Dietary selenium deficiency	0.016	0.796	0.188
E58 Dietary calcium deficiency	0.016	0.796	0.188
E54 Ascorbic acid deficiency	0.016	0.796	0.188
E52 Niacin deficiency [pellagra]	0.016	0.796	0.188
O32.2 Maternal care for transverse and oblique lie	0.000	0.797	0.203
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.000	0.798	0.202
O34.2 Maternal care due to uterine scar from previous surgery	0.000	0.798	0.202
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.798	0.201
E04.1 Non-toxic single thyroid nodule	0.198	0.799	0.003
I21 Acute myocardial infarction	0.201	0.799	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.799	0.201
E04.2 Non-toxic multinodular goitre	0.198	0.799	0.003
E29 Testicular dysfunction	0.006	0.800	0.194
O43.1 Malformation of placenta	0.000	0.801	0.199
O47.0 False labour before 37 completed weeks of gestation	0.000	0.801	0.199
O62 Abnormalities of forces of labour	0.000	0.801	0.198
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.000	0.802	0.198
O32.9 Maternal care for malpresentation of foetus, unspecified	0.000	0.802	0.198
O32.6 Maternal care for compound presentation	0.000	0.802	0.198
O32.4 Maternal care for high head at term	0.000	0.802	0.198
O32.3 Maternal care for face, brow and chin presentation	0.000	0.802	0.198
E22 Hyperfunction of pituitary gland	0.005	0.803	0.192
O34.7 Maternal care for abnormality of vulva and perineum	0.000	0.803	0.197
O74 Complications of anaesthesia during labour and delivery	0.000	0.803	0.197
O65 Obstructed labour due to maternal pelvic abnormality	0.000	0.803	0.197
O60 Preterm delivery	0.000	0.803	0.197
O71 Other obstetric trauma	0.000	0.804	0.196
E55.9 Vitamin D deficiency, unspecified	0.004	0.805	0.191
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.000	0.806	0.194
O75 Other complications of labour and delivery, not elsewhere classified	0.000	0.806	0.194
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.000	0.807	0.193
E27 Other disorders of adrenal gland	0.006	0.808	0.186
E44 Protein-energy malnutrition of moderate and mild degree	0.016	0.808	0.176
E45 Retarded development following protein-energy malnutrition	0.016	0.808	0.176
E43 Unspecified severe protein-energy malnutrition	0.016	0.808	0.176
E42 Marasmic kwashiorkor	0.016	0.808	0.176
E41 Nutritional marasmus	0.016	0.808	0.176
E40 Kwashiorkor	0.016	0.808	0.176
O63.2 Delayed delivery of second twin, triplet, etc.	0.000	0.809	0.191
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.000	0.809	0.191
O34.8 Maternal care for other abnormalities of pelvic organs	0.000	0.809	0.191
O34.6 Maternal care for abnormality of vagina	0.000	0.809	0.191
O34.5 Maternal care for other abnormalities of gravid uterus	0.000	0.809	0.191
O34.4 Maternal care for other abnormalities of cervix	0.000	0.809	0.191
O34.3 Maternal care for cervical incompetence	0.000	0.809	0.191
O34.0 Maternal care for congenital malformation of uterus	0.000	0.809	0.191
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.811	0.189
O47.9 False labour, unspecified	0.000	0.815	0.185
O69.9 Labour and delivery complicated by cord complication, unspecified	0.000	0.816	0.184
O69.5 Labour and delivery complicated by vascular lesion of cord	0.000	0.816	0.184
O69.4 Labour and delivery complicated by vasa praevia	0.000	0.816	0.184
O69.3 Labour and delivery complicated by short cord	0.000	0.816	0.184
O69.0 Labour and delivery complicated by prolapse of cord	0.000	0.816	0.184
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.000	0.816	0.184
E46 Unspecified protein-energy malnutrition	0.015	0.816	0.169
O72.3 Postpartum coagulation defects	0.000	0.818	0.182
I20-I25 Ischaemic heart diseases	0.181	0.819	0.000
O32.8 Maternal care for other malpresentation of foetus	0.000	0.819	0.181
O30.0 Twin pregnancy	0.000	0.820	0.180
O36.0 Maternal care for rhesus isoimmunisation	0.000	0.820	0.180
O72.2 Delayed and secondary postpartum haemorrhage	0.000	0.820	0.180
O43.9 Placental disorder, unspecified	0.000	0.822	0.178
O43.2 Morbidly adherent placenta	0.000	0.822	0.178
O43.0 Placental transfusion syndromes	0.000	0.822	0.178
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.000	0.822	0.178
I20 Angina pectoris	0.178	0.822	0.000
E65-E68 Obesity and other hyperalimentation	0.022	0.823	0.155
E35 Disorders of endocrine glands in diseases classified elsewhere	0.007	0.824	0.169
E32 Diseases of thymus	0.007	0.824	0.169
E31 Polyglandular dysfunction	0.007	0.824	0.169
E30 Disorders of puberty, not elsewhere classified	0.007	0.824	0.169
E25 Adrenogenital disorders	0.007	0.824	0.169
E20 Hypoparathyroidism	0.007	0.824	0.169
O62.2 Other uterine inertia	0.000	0.825	0.175
O73 Retained placenta and membranes, without haemorrhage	0.000	0.826	0.174
O30.9 Multiple gestation, unspecified	0.000	0.826	0.173
O30.8 Other multiple gestation	0.000	0.826	0.173
O30.2 Quadruplet pregnancy	0.000	0.826	0.173
O30.1 Triplet pregnancy	0.000	0.826	0.173
I20.9 Angina pectoris, unspecified	0.173	0.827	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.172	0.828	0.000
O85-O92 Complications predominantly related to the puerperium	0.000	0.828	0.172
I21.1 Acute transmural myocardial infarction of inferior wall	0.170	0.830	0.000
O61 Failed induction of labour	0.000	0.830	0.170
E34 Other endocrine disorders	0.007	0.831	0.162
E27.1 Primary adrenocortical insufficiency	0.002	0.831	0.167
O31.8 Other complications specific to multiple gestation	0.000	0.831	0.169
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.000	0.831	0.169
O31.1 Continuing pregnancy after abortion of one foetus or more	0.000	0.831	0.169
O31.0 Papyraceous foetus	0.000	0.831	0.169
O33.9 Maternal care for disproportion, unspecified	0.000	0.831	0.169
O33.8 Maternal care for disproportion of other origin	0.000	0.831	0.169
O33.7 Maternal care for disproportion due to other foetal deformities	0.000	0.831	0.169
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.000	0.831	0.169
O33.5 Maternal care for disproportion due to unusually large foetus	0.000	0.831	0.169
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.000	0.831	0.169
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.000	0.831	0.169
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.000	0.831	0.169
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.000	0.831	0.169
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.000	0.831	0.169
O45.9 Premature separation of placenta, unspecified	0.000	0.831	0.169
O45.8 Other premature separation of placenta	0.000	0.831	0.169
O45.0 Premature separation of placenta with coagulation defect	0.000	0.831	0.169
O44.0 Placenta praevia specified as without haemorrhage	0.000	0.832	0.168
E29.1 Testicular hypofunction	0.003	0.832	0.165
E55.0 Rickets, active	0.008	0.833	0.158
O43.8 Other placental disorders	0.000	0.834	0.166
O75.2 Pyrexia during labour, not elsewhere classified	0.000	0.834	0.166
E23 Hypofunction and other disorders of pituitary gland	0.006	0.834	0.159
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.000	0.836	0.164
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.836	0.164
O97 Death from sequelae of direct obstetric causes	0.000	0.836	0.164
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.000	0.836	0.164
O95 Obstetric death of unspecified cause	0.000	0.836	0.164
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.000	0.836	0.164
O66.0 Obstructed labour due to shoulder dystocia	0.000	0.837	0.163
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.003	0.837	0.160
O80-O84 Delivery	0.000	0.837	0.163
E26 Hyperaldosteronism	0.008	0.838	0.155
O69.8 Labour and delivery complicated by other cord complications	0.000	0.838	0.161
E53.8 Deficiency of other specified B group vitamins	0.004	0.839	0.158
E24 Cushing's syndrome	0.008	0.839	0.153
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.000	0.839	0.161
O64.8 Obstructed labour due to other malposition and malpresentation	0.000	0.839	0.161
O64.5 Obstructed labour due to compound presentation	0.000	0.839	0.161
O64.4 Obstructed labour due to shoulder presentation	0.000	0.839	0.161
O64.3 Obstructed labour due to brow presentation	0.000	0.839	0.161
O64.2 Obstructed labour due to face presentation	0.000	0.839	0.161
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.840	0.160
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.000	0.841	0.159
I22 Subsequent myocardial infarction	0.158	0.842	0.000
E70-E90 Metabolic disorders	0.024	0.845	0.131
O41 Other disorders of amniotic fluid and membranes	0.000	0.846	0.153
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.000	0.846	0.153
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.000	0.846	0.153
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.000	0.846	0.153
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.000	0.846	0.153
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.000	0.846	0.153
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.000	0.846	0.153
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.000	0.846	0.153
E53.9 Vitamin B deficiency, unspecified	0.008	0.847	0.144
E53.1 Pyridoxine deficiency	0.008	0.847	0.144
E53.0 Riboflavin deficiency	0.008	0.847	0.144
I21.2 Acute transmural myocardial infarction of other sites	0.152	0.848	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.000	0.849	0.151
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.000	0.850	0.150
O36.4 Maternal care for intra-uterine death	0.000	0.850	0.150
O36.3 Maternal care for signs of foetal hypoxia	0.000	0.850	0.150
O36.2 Maternal care for hydrops foetalis	0.000	0.850	0.150
O36.1 Maternal care for other isoimmunisation	0.000	0.850	0.150
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.000	0.850	0.150
E05.0 Thyrotoxicosis with diffuse goitre	0.140	0.850	0.009
O63.0 Prolonged first stage (of labour)	0.000	0.850	0.149
O36.9 Maternal care for foetal problem, unspecified	0.000	0.851	0.149
O36.6 Maternal care for excessive foetal growth	0.000	0.851	0.149
O66.9 Obstructed labour, unspecified	0.000	0.852	0.148
O66.8 Other specified obstructed labour	0.000	0.852	0.148
O66.4 Failed trial of labour, unspecified	0.000	0.852	0.148
O66.3 Obstructed labour due to other abnormalities of foetus	0.000	0.852	0.148
O66.2 Obstructed labour due to unusually large foetus	0.000	0.852	0.148
O66.1 Obstructed labour due to locked twins	0.000	0.852	0.148
E28 Ovarian dysfunction	0.008	0.852	0.140
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.853	0.147
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.147	0.853	0.000
E50.9 Vitamin A deficiency, unspecified	0.012	0.854	0.135
E50.8 Other manifestations of vitamin A deficiency	0.012	0.854	0.135
E50.7 Other ocular manifestations of vitamin A deficiency	0.012	0.854	0.135
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.012	0.854	0.135
E50.5 Vitamin A deficiency with night blindness	0.012	0.854	0.135
E50.4 Vitamin A deficiency with keratomalacia	0.012	0.854	0.135
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.012	0.854	0.135
E50.2 Vitamin A deficiency with corneal xerosis	0.012	0.854	0.135
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.012	0.854	0.135
E50.0 Vitamin A deficiency with conjunctival xerosis	0.012	0.854	0.135
E51.9 Thiamine deficiency, unspecified	0.012	0.854	0.135
E51.8 Other manifestations of thiamine deficiency	0.012	0.854	0.135
E51.2 Wernicke's encephalopathy	0.012	0.854	0.135
E51.1 Beriberi	0.012	0.854	0.135
E56.9 Vitamin deficiency, unspecified	0.012	0.854	0.135
E56.8 Deficiency of other vitamins	0.012	0.854	0.135
E56.1 Deficiency of vitamin K	0.012	0.854	0.135
E56.0 Deficiency of vitamin E	0.012	0.854	0.135
E63.9 Nutritional deficiency, unspecified	0.012	0.854	0.135
E63.8 Other specified nutritional deficiencies	0.012	0.854	0.135
E63.1 Imbalance of constituents of food intake	0.012	0.854	0.135
E63.0 Essential fatty acid [EFA] deficiency	0.012	0.854	0.135
E64.9 Sequelae of unspecified nutritional deficiency	0.012	0.854	0.135
E64.8 Sequelae of other nutritional deficiencies	0.012	0.854	0.135
E64.3 Sequelae of rickets	0.012	0.854	0.135
E64.2 Sequelae of vitamin C deficiency	0.012	0.854	0.135
E64.1 Sequelae of vitamin A deficiency	0.012	0.854	0.135
E64.0 Sequelae of protein-energy malnutrition	0.012	0.854	0.135
O67.8 Other intrapartum haemorrhage	0.000	0.855	0.145
O67.0 Intrapartum haemorrhage with coagulation defect	0.000	0.855	0.145
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.000	0.855	0.144
I21.X Presumed acute myicardial infaction (unconfirmed)	0.144	0.856	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.856	0.144
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.856	0.144
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.856	0.144
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.856	0.144
I20.0 Unstable angina	0.144	0.856	0.000
E29.9 Testicular dysfunction, unspecified	0.004	0.856	0.139
E29.8 Other testicular dysfunction	0.004	0.856	0.139
E29.0 Testicular hyperfunction	0.004	0.856	0.139
O71.4 Obstetric high vaginal laceration alone	0.000	0.857	0.143
O62.9 Abnormality of forces of labour, unspecified	0.000	0.857	0.142
O62.8 Other abnormalities of forces of labour	0.000	0.857	0.142
O62.0 Primary inadequate contractions	0.000	0.857	0.142
E22.0 Acromegaly and pituitary gigantism	0.004	0.858	0.139
E22.9 Hyperfunction of pituitary gland, unspecified	0.004	0.858	0.138
E22.8 Other hyperfunction of pituitary gland	0.004	0.858	0.138
E22.1 Hyperprolactinaemia	0.004	0.858	0.138
I23 Certain current complications following acute myocardial infarction	0.142	0.858	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.858	0.141
O60.3 Preterm delivery without spontaneous labour	0.000	0.859	0.141
O60.2 Preterm spontaneous labour with term delivery	0.000	0.859	0.141
O60.1 Preterm spontaneous labour with preterm delivery	0.000	0.859	0.141
O60.0 Preterm labour without delivery	0.000	0.859	0.141
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.000	0.859	0.141
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.000	0.859	0.141
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.000	0.859	0.141
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.000	0.859	0.141
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.000	0.859	0.141
O65.2 Obstructed labour due to pelvic inlet contraction	0.000	0.859	0.141
O65.1 Obstructed labour due to generally contracted pelvis	0.000	0.859	0.141
O65.0 Obstructed labour due to deformed pelvis	0.000	0.859	0.141
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.000	0.859	0.141
O74.8 Other complications of anaesthesia during labour and delivery	0.000	0.859	0.141
O74.7 Failed or difficult intubation during labour and delivery	0.000	0.859	0.141
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.000	0.859	0.141
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.000	0.859	0.141
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.000	0.859	0.141
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.000	0.859	0.141
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.000	0.859	0.141
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.000	0.859	0.141
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.000	0.859	0.141
O71.9 Obstetric trauma, unspecified	0.000	0.859	0.141
O71.7 Obstetric haematoma of pelvis	0.000	0.859	0.141
O71.6 Obstetric damage to pelvic joints and ligaments	0.000	0.859	0.141
O71.5 Other obstetric injury to pelvic organs	0.000	0.859	0.141
O71.3 Obstetric laceration of cervix	0.000	0.859	0.141
O71.2 Postpartum inversion of uterus	0.000	0.859	0.141
O71.1 Rupture of uterus during labour	0.000	0.859	0.141
O71.0 Rupture of uterus before onset of labour	0.000	0.859	0.141
I21.3 Acute transmural myocardial infarction of unspecified site	0.140	0.859	0.000
E61 Deficiency of other nutrient elements	0.020	0.860	0.120
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.861	0.139
O75.9 Complication of labour and delivery, unspecified	0.000	0.861	0.139
O75.5 Delayed delivery after artificial rupture of membranes	0.000	0.861	0.139
O75.4 Other complications of obstetric surgery and procedures	0.000	0.861	0.139
O75.3 Other infection during labour	0.000	0.861	0.139
O75.1 Shock during or following labour and delivery	0.000	0.861	0.139
I22.1 Subsequent myocardial infarction of inferior wall	0.139	0.861	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.006	0.861	0.133
O71.8 Other specified obstetric trauma	0.000	0.862	0.138
E27.5 Adrenomedullary hyperfunction	0.004	0.862	0.134
E27.3 Drug-induced adrenocortical insufficiency	0.004	0.862	0.134
E27.2 Addisonian crisis	0.004	0.862	0.134
E27.0 Other adrenocortical overactivity	0.004	0.862	0.134
E44.1 Mild protein-energy malnutrition	0.011	0.862	0.126
E44.0 Moderate protein-energy malnutrition	0.011	0.862	0.126
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.000	0.862	0.137
O64.1 Obstructed labour due to breech presentation	0.000	0.863	0.136
O36.5 Maternal care for poor foetal growth	0.000	0.865	0.135
O75.0 Maternal distress during labour and delivery	0.000	0.866	0.134
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.866	0.134
I20.8 Other forms of angina pectoris	0.134	0.866	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.004	0.868	0.129
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.868	0.132
E83 Disorders of mineral metabolism	0.016	0.868	0.115
I25 Chronic ischaemic heart disease	0.130	0.870	0.000
O90 Complications of the puerperium, not elsewhere classified	0.000	0.872	0.128
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.000	0.872	0.128
E27.8 Other specified disorders of adrenal gland	0.004	0.872	0.124
E67 Other hyperalimentation	0.016	0.873	0.111
E68 Sequelae of hyperalimentation	0.016	0.873	0.111
E20.9 Hypoparathyroidism, unspecified	0.005	0.873	0.121
E20.8 Other hypoparathyroidism	0.005	0.873	0.121
E20.1 Pseudohypoparathyroidism	0.005	0.873	0.121
E20.0 Idiopathic hypoparathyroidism	0.005	0.873	0.121
E25.9 Adrenogenital disorder, unspecified	0.005	0.873	0.121
E25.8 Other adrenogenital disorders	0.005	0.873	0.121
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.005	0.873	0.121
E30.9 Disorder of puberty, unspecified	0.005	0.873	0.121
E30.8 Other disorders of puberty	0.005	0.873	0.121
E30.1 Precocious puberty	0.005	0.873	0.121
E30.0 Delayed puberty	0.005	0.873	0.121
E31.9 Polyglandular dysfunction, unspecified	0.005	0.873	0.121
E31.8 Other polyglandular dysfunction	0.005	0.873	0.121
E31.1 Polyglandular hyperfunction	0.005	0.873	0.121
E31.0 Autoimmune polyglandular failure	0.005	0.873	0.121
E32.9 Disease of thymus, unspecified	0.005	0.873	0.121
E32.8 Other diseases of thymus	0.005	0.873	0.121
E32.1 Abscess of thymus	0.005	0.873	0.121
E32.0 Persistent hyperplasia of thymus	0.005	0.873	0.121
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.005	0.873	0.121
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.005	0.873	0.121
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.005	0.873	0.121
E34.9 Endocrine disorder, unspecified	0.005	0.874	0.122
E23.2 Diabetes insipidus	0.004	0.875	0.121
I20.1 Angina pectoris with documented spasm	0.124	0.876	0.000
O00-O08 Pregnancy with abortive outcome	0.000	0.876	0.124
I25.1 Atherosclerotic heart disease	0.124	0.876	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.000	0.876	0.123
O91 Infections of breast associated with childbirth	0.000	0.876	0.123
O89 Complications of anaesthesia during the puerperium	0.000	0.876	0.123

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations