TreeWAS – Variant ID: rs17342717

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E83.1 Disorders of iron metabolism	1.000	0.000	0.000
D45 Polycythaemia vera	0.998	0.002	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.731	0.269	0.000
D46 Myelodysplastic syndromes	0.662	0.338	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.609	0.391	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.581	0.419	0.000
D46.1 Refractory anaemia with sideroblasts	0.558	0.442	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.556	0.444	0.000
D46.2 Refractory anaemia with excess of blasts	0.551	0.449	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.543	0.457	0.000
D44.6 Carotid body	0.540	0.460	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.524	0.476	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.524	0.476	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.513	0.487	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.513	0.487	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.510	0.490	0.000
D48.6 Breast	0.489	0.511	0.000
D38.0 Larynx	0.476	0.524	0.000
D46.7 Other myelodysplastic syndromes	0.475	0.525	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.475	0.525	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.475	0.525	0.000
D46.4 Refractory anaemia, unspecified	0.475	0.525	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.475	0.525	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.475	0.525	0.000
D37.5 Rectum	0.473	0.527	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.467	0.533	0.000
D37.2 Small intestine	0.466	0.534	0.000
D44.9 Endocrine gland, unspecified	0.436	0.563	0.000
D44.8 Pluriglandular involvement	0.436	0.563	0.000
D44.7 Aortic body and other paraganglia	0.436	0.563	0.000
D44.5 Pineal gland	0.436	0.563	0.000
D44.4 Craniopharyngeal duct	0.436	0.563	0.000
D44.2 Parathyroid gland	0.436	0.563	0.000
D44.1 Adrenal gland	0.436	0.563	0.000
D44.0 Thyroid gland	0.436	0.563	0.000
D37.1 Stomach	0.435	0.565	0.000
D48.5 Skin	0.422	0.578	0.000
D37.6 Liver, gallbladder and bile ducts	0.421	0.579	0.000
D38.6 Respiratory organ, unspecified	0.417	0.583	0.000
D38.5 Other respiratory organs	0.417	0.583	0.000
D38.4 Thymus	0.417	0.583	0.000
D38.3 Mediastinum	0.417	0.583	0.000
D38.2 Pleura	0.417	0.583	0.000
D43.0 Brain, supratentorial	0.415	0.585	0.000
D38.1 Trachea, bronchus and lung	0.414	0.586	0.000
D37.3 Appendix	0.399	0.601	0.000
D44.3 Pituitary gland	0.391	0.609	0.000
D40.0 Prostate	0.390	0.610	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.390	0.610	0.000
D48.4 Peritoneum	0.390	0.610	0.000
D48.3 Retroperitoneum	0.390	0.610	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.390	0.610	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.386	0.614	0.000
D41.2 Ureter	0.385	0.615	0.000
D37.0 Lip, oral cavity and pharynx	0.378	0.622	0.000
D40.9 Male genital organ, unspecified	0.376	0.624	0.000
D40.7 Other male genital organs	0.376	0.624	0.000
D42.9 Meninges, unspecified	0.376	0.624	0.000
D42.1 Spinal meninges	0.376	0.624	0.000
D42.0 Cerebral meninges	0.376	0.624	0.000
D39.0 Uterus	0.370	0.629	0.000
D39.9 Female genital organ, unspecified	0.368	0.632	0.000
D39.7 Other female genital organs	0.368	0.632	0.000
D39.2 Placenta	0.368	0.632	0.000
D43.9 Central nervous system, unspecified	0.366	0.634	0.000
D43.7 Other parts of central nervous system	0.366	0.634	0.000
D43.4 Spinal cord	0.366	0.634	0.000
D43.3 Cranial nerves	0.366	0.634	0.000
D43.1 Brain, infratentorial	0.366	0.634	0.000
D40.1 Testis	0.361	0.639	0.000
D37.9 Digestive organ, unspecified	0.356	0.644	0.000
D48.7 Other specified sites	0.356	0.644	0.000
D39.1 Ovary	0.354	0.646	0.000
D48.0 Bone and articular cartilage	0.337	0.662	0.000
D41.9 Urinary organ, unspecified	0.335	0.665	0.000
D41.7 Other urinary organs	0.335	0.665	0.000
D41.3 Urethra	0.335	0.665	0.000
D41.1 Renal pelvis	0.335	0.665	0.000
D37.4 Colon	0.329	0.671	0.000
D41.0 Kidney	0.320	0.679	0.000
D47.1 Chronic myeloproliferative disease	0.279	0.721	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.277	0.723	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.277	0.723	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.277	0.723	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.277	0.723	0.000
D47.2 Monoclonal gammopathy	0.273	0.727	0.000
D43.2 Brain, unspecified	0.271	0.728	0.000
D47.4 Osteomyelofibrosis	0.268	0.732	0.000
D37.7 Other digestive organs	0.251	0.749	0.000
D48.1 Connective and other soft tissue	0.249	0.750	0.000
D64.9 Anaemia, unspecified	0.000	0.790	0.210
K74.0 Hepatic fibrosis	0.207	0.793	0.000
K74 Fibrosis and cirrhosis of liver	0.204	0.796	0.000
K76 Other diseases of liver	0.201	0.799	0.000
K76.6 Portal hypertension	0.194	0.806	0.000
K74.6 Other and unspecified cirrhosis of liver	0.193	0.807	0.000
K70-K77 Diseases of liver	0.191	0.809	0.000
D41.4 Bladder	0.188	0.812	0.000
K76.9 Liver disease, unspecified	0.185	0.815	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.184	0.816	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.159	0.840	0.001
K76.7 Hepatorenal syndrome	0.160	0.840	0.000
K73 Chronic hepatitis, not elsewhere classified	0.150	0.850	0.000
K74.5 Biliary cirrhosis, unspecified	0.147	0.853	0.000
K74.4 Secondary biliary cirrhosis	0.146	0.854	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.146	0.854	0.000
K74.1 Hepatic sclerosis	0.146	0.854	0.000
K76.5 Hepatic veno-occlusive disease	0.144	0.855	0.000
K76.4 Peliosis hepatis	0.144	0.855	0.000
K76.3 Infarction of liver	0.144	0.855	0.000
K76.2 Central haemorrhagic necrosis of liver	0.144	0.855	0.000
K76.1 Chronic passive congestion of liver	0.144	0.855	0.000
K76.8 Other specified diseases of liver	0.140	0.860	0.000
K77 Liver disorders in diseases classified elsewhere	0.137	0.863	0.000
K71 Toxic liver disease	0.137	0.863	0.000
E83 Disorders of mineral metabolism	0.126	0.874	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.123	0.877	0.000
K70 Alcoholic liver disease	0.122	0.878	0.000
D64 Other anaemias	0.000	0.878	0.122
K74.3 Primary biliary cirrhosis	0.121	0.879	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.108	0.892	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.108	0.892	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.108	0.892	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.108	0.892	0.000
K73.9 Chronic hepatitis, unspecified	0.106	0.894	0.000
K71.9 Toxic liver disease, unspecified	0.098	0.901	0.000
K71.8 Toxic liver disease with other disorders of liver	0.098	0.901	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.098	0.901	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.098	0.901	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.098	0.901	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.098	0.901	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.098	0.901	0.000
K71.2 Toxic liver disease with acute hepatitis	0.098	0.901	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.098	0.901	0.000
K71.0 Toxic liver disease with cholestasis	0.098	0.901	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.098	0.901	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.098	0.901	0.000
K72 Hepatic failure, not elsewhere classified	0.098	0.902	0.000
K70.0 Alcoholic fatty liver	0.092	0.908	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.091	0.909	0.000
E83.8 Other disorders of mineral metabolism	0.091	0.909	0.000
E83.2 Disorders of zinc metabolism	0.091	0.909	0.000
E83.0 Disorders of copper metabolism	0.091	0.909	0.000
K70.3 Alcoholic cirrhosis of liver	0.088	0.912	0.000
D64.4 Congenital dyserythropoietic anaemia	0.000	0.912	0.087
D64.3 Other sideroblastic anaemias	0.000	0.912	0.087
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.000	0.912	0.087
D64.1 Secondary sideroblastic anaemia due to disease	0.000	0.912	0.087
D64.0 Hereditary sideroblastic anaemia	0.000	0.912	0.087
D64.8 Other specified anaemias	0.000	0.913	0.087
K75 Other inflammatory liver diseases	0.084	0.915	0.000
K70.4 Alcoholic hepatic failure	0.082	0.917	0.000
K70.1 Alcoholic hepatitis	0.076	0.923	0.000
K72.1 Chronic hepatic failure	0.070	0.930	0.000
E83.3 Disorders of phosphorus metabolism	0.070	0.930	0.000
K75.0 Abscess of liver	0.066	0.934	0.000
K75.8 Other specified inflammatory liver diseases	0.065	0.934	0.000
K72.0 Acute and subacute hepatic failure	0.064	0.936	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.060	0.939	0.000
K75.2 Nonspecific reactive hepatitis	0.060	0.939	0.000
K75.1 Phlebitis of portal vein	0.060	0.939	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.061	0.939	0.000
E70-E90 Metabolic disorders	0.060	0.940	0.000
E80.1 Porphyria cutanea tarda	0.060	0.940	0.000
D60-D64 Aplastic and other anaemias	0.000	0.940	0.060
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.058	0.942	0.000
E83.4 Disorders of magnesium metabolism	0.055	0.945	0.000
G35 Multiple sclerosis	0.054	0.946	0.000
E89.0 Postprocedural hypothyroidism	0.051	0.949	0.000
E80.2 Other porphyria	0.050	0.950	0.000
D62 Acute posthaemorrhagic anaemia	0.000	0.951	0.049
E85 Amyloidosis	0.048	0.952	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.048	0.952	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.048	0.952	0.000
G37 Other demyelinating diseases of central nervous system	0.048	0.952	0.000
E89.2 Postprocedural hypoparathyroidism	0.047	0.953	0.000
E80.6 Other disorders of bilirubin metabolism	0.047	0.953	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.046	0.954	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.044	0.956	0.000
E80.5 Crigler-Najjar syndrome	0.044	0.956	0.000
E80.3 Defects of catalase and peroxydase	0.044	0.956	0.000
E80.0 Hereditary erythropoietic porphyria	0.044	0.956	0.000
E84 Cystic fibrosis	0.043	0.956	0.000
E79 Disorders of purine and pyrimidine metabolism	0.043	0.956	0.000
E77 Disorders of glycoprotein metabolism	0.043	0.956	0.000
E76 Disorders of glycosaminoglycan metabolism	0.043	0.956	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.043	0.956	0.000
E72 Other disorders of amino-acid metabolism	0.043	0.956	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.043	0.956	0.000
E70 Disorders of aromatic amino-acid metabolism	0.043	0.956	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.043	0.956	0.000
E73 Lactose intolerance	0.043	0.957	0.000
E80.4 Gilbert's syndrome	0.043	0.957	0.000
K72.9 Hepatic failure, unspecified	0.043	0.957	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.000	0.957	0.043
E74 Other disorders of carbohydrate metabolism	0.041	0.958	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.041	0.958	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.041	0.958	0.000
E89.5 Postprocedural testicular hypofunction	0.041	0.958	0.000
E89.4 Postprocedural ovarian failure	0.041	0.958	0.000
E89.1 Postprocedural hypoinsulinaemia	0.041	0.958	0.000
E89.3 Postprocedural hypopituitarism	0.041	0.959	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.040	0.960	0.000
E85.8 Other amyloidosis	0.040	0.960	0.000
E88 Other metabolic disorders	0.039	0.961	0.000
K75.4 Autoimmune hepatitis	0.038	0.962	0.001
D50.9 Iron deficiency anaemia, unspecified	0.000	0.962	0.038
E85.4 Organ-limited amyloidosis	0.038	0.962	0.000
D50 Iron deficiency anaemia	0.000	0.963	0.037
D61 Other aplastic anaemias	0.000	0.964	0.036
E85.3 Secondary systemic amyloidosis	0.035	0.965	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.035	0.965	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.035	0.965	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.035	0.965	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.965	0.035
D50-D53 Nutritional anaemias	0.000	0.965	0.034
G36 Other acute disseminated demyelination	0.034	0.966	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.034	0.966	0.000
G37.5 Concentric sclerosis [Balo]	0.034	0.966	0.000
G37.4 Subacute necrotising myelitis	0.034	0.966	0.000
G37.2 Central pontine myelinolysis	0.034	0.966	0.000
G37.1 Central demyelination of corpus callosum	0.034	0.966	0.000
G37.0 Diffuse sclerosis	0.034	0.966	0.000
D50.8 Other iron deficiency anaemias	0.000	0.967	0.033
E88.8 Other specified metabolic disorders	0.032	0.968	0.000
K70.9 Alcoholic liver disease, unspecified	0.032	0.968	0.000
E85.9 Amyloidosis, unspecified	0.031	0.968	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.031	0.968	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.031	0.968	0.000
E70.3 Albinism	0.031	0.968	0.000
E70.2 Disorders of tyrosine metabolism	0.031	0.968	0.000
E70.1 Other hyperphenylalaninaemias	0.031	0.968	0.000
E70.0 Classical phenylketonuria	0.031	0.968	0.000
E71.3 Disorders of fatty-acid metabolism	0.031	0.968	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.031	0.968	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.031	0.968	0.000
E71.0 Maple-syrup-urine disease	0.031	0.968	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.031	0.968	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.031	0.968	0.000
E72.5 Disorders of glycine metabolism	0.031	0.968	0.000
E72.4 Disorders of ornithine metabolism	0.031	0.968	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.031	0.968	0.000
E72.2 Disorders of urea cycle metabolism	0.031	0.968	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.031	0.968	0.000
E72.0 Disorders of amino-acid transport	0.031	0.968	0.000
E75.6 Lipid storage disorder, unspecified	0.031	0.968	0.000
E75.5 Other lipid storage disorders	0.031	0.968	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.031	0.968	0.000
E75.3 Sphingolipidosis, unspecified	0.031	0.968	0.000
E75.2 Other sphingolipidosis	0.031	0.968	0.000
E75.1 Other gangliosidosis	0.031	0.968	0.000
E75.0 GM2 gangliosidosis	0.031	0.968	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.031	0.968	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.031	0.968	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.031	0.968	0.000
E76.2 Other mucopolysaccharidoses	0.031	0.968	0.000
E76.1 Mucopolysaccharidosis, type II	0.031	0.968	0.000
E76.0 Mucopolysaccharidosis, type I	0.031	0.968	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.031	0.968	0.000
E77.8 Other disorders of glycoprotein metabolism	0.031	0.968	0.000
E77.1 Defects in glycoprotein degradation	0.031	0.968	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.031	0.968	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.031	0.968	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.031	0.968	0.000
E79.1 Lesch-Nyhan syndrome	0.031	0.968	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.031	0.968	0.000
E84.9 Cystic fibrosis, unspecified	0.031	0.968	0.000
E84.8 Cystic fibrosis with other manifestations	0.031	0.968	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.031	0.968	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.031	0.968	0.000
E73.8 Other lactose intolerance	0.031	0.969	0.000
E73.1 Secondary lactase deficiency	0.031	0.969	0.000
E73.0 Congenital lactase deficiency	0.031	0.969	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.000	0.969	0.031
D60.8 Other acquired pure red cell aplasias	0.000	0.969	0.031
D60.1 Transient acquired pure red cell aplasia	0.000	0.969	0.031
D60.0 Chronic acquired pure red cell aplasia	0.000	0.969	0.031
E73.9 Lactose intolerance, unspecified	0.031	0.969	0.000
D80-D89 Certain disorders involving the immune mechanism	0.000	0.970	0.030
E74.9 Disorder of carbohydrate metabolism, unspecified	0.030	0.970	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.030	0.970	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.030	0.970	0.000
E74.2 Disorders of galactose metabolism	0.030	0.970	0.000
E74.1 Disorders of fructose metabolism	0.030	0.970	0.000
E74.0 Glycogen storage disease	0.030	0.970	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.971	0.029
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.972	0.028
E88.9 Metabolic disorder, unspecified	0.028	0.972	0.000
E88.3 Tumour lysis syndrome	0.028	0.972	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.028	0.972	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.028	0.972	0.000
E88.2 Lipomatosis, not elsewhere classified	0.028	0.972	0.000
D50.1 Sideropenic dysphagia	0.000	0.973	0.027
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.000	0.974	0.026
D61.8 Other specified aplastic anaemias	0.000	0.974	0.026
D61.3 Idiopathic aplastic anaemia	0.000	0.974	0.026
D61.2 Aplastic anaemia due to other external agents	0.000	0.974	0.026
D61.1 Drug-induced aplastic anaemia	0.000	0.974	0.026
D61.0 Constitutional aplastic anaemia	0.000	0.974	0.026
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.974	0.026
D55-D59 Haemolytic anaemias	0.000	0.974	0.025
G36.9 Acute disseminated demyelination, unspecified	0.025	0.975	0.000
G36.8 Other specified acute disseminated demyelination	0.025	0.975	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.025	0.975	0.000
G36.0 Neuromyelitis optica [Devic]	0.025	0.975	0.000
D52 Folate deficiency anaemia	0.000	0.976	0.024
D53 Other nutritional anaemias	0.000	0.977	0.023
K75.9 Inflammatory liver disease, unspecified	0.021	0.978	0.002
D82 Immunodeficiency associated with other major defects	0.000	0.978	0.022
D81 Combined immunodeficiencies	0.000	0.978	0.022
D84 Other immunodeficiencies	0.000	0.978	0.021
D86 Sarcoidosis	0.000	0.979	0.021
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.979	0.021
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.979	0.021
D89.3 Immune reconstitution syndrome	0.000	0.979	0.021
D89.1 Cryoglobulinaemia	0.000	0.979	0.021
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.979	0.021
D83 Common variable immunodeficiency	0.000	0.979	0.020
D80 Immunodeficiency with predominantly antibody defects	0.000	0.980	0.020
D59 Acquired haemolytic anaemia	0.000	0.980	0.020
D61.9 Aplastic anaemia, unspecified	0.000	0.981	0.019
D51 Vitamin B12 deficiency anaemia	0.000	0.981	0.019
D63.1 Anaemia in other chronic diseases classified elsewhere	0.000	0.981	0.019
E83.5 Disorders of calcium metabolism	0.018	0.981	0.000
D57 Sickle-cell disorders	0.000	0.981	0.018
D55 Anaemia due to enzyme disorders	0.000	0.981	0.018
D58 Other hereditary haemolytic anaemias	0.000	0.982	0.018
R30.0 Dysuria	0.018	0.982	0.000
D52.8 Other folate deficiency anaemias	0.000	0.982	0.018
D52.1 Drug-induced folate deficiency anaemia	0.000	0.982	0.018
D52.0 Dietary folate deficiency anaemia	0.000	0.982	0.018
D56 Thalassaemia	0.000	0.983	0.017
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.017	0.983	0.000
D52.9 Folate deficiency anaemia, unspecified	0.000	0.983	0.017
D53.8 Other specified nutritional anaemias	0.000	0.983	0.017
D53.2 Scorbutic anaemia	0.000	0.983	0.017
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.000	0.983	0.017
D53.0 Protein deficiency anaemia	0.000	0.983	0.017
D86.9 Sarcoidosis, unspecified	0.000	0.983	0.017
D86.1 Sarcoidosis of lymph nodes	0.000	0.984	0.016
D59.1 Other autoimmune haemolytic anaemias	0.000	0.984	0.016
D81.9 Combined immunodeficiency, unspecified	0.000	0.984	0.016
D81.8 Other combined immunodeficiencies	0.000	0.984	0.016
D81.7 Major histocompatibility complex class II deficiency	0.000	0.984	0.016
D81.6 Major histocompatibility complex class I deficiency	0.000	0.984	0.016
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.984	0.016
D81.4 Nezelof's syndrome	0.000	0.984	0.016
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.984	0.016
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.984	0.016
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.984	0.016
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.984	0.016
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.984	0.016
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.984	0.016
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.984	0.016
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.984	0.016
D82.2 Immunodeficiency with short-limbed stature	0.000	0.984	0.016
D82.1 Di George's syndrome	0.000	0.984	0.016
D82.0 Wiskott-Aldrich syndrome	0.000	0.984	0.016
D84.8 Other specified immunodeficiencies	0.000	0.984	0.016
D84.1 Defects in the complement system	0.000	0.984	0.016
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.984	0.016
J93.9 Pneumothorax, unspecified	0.000	0.984	0.016
D86.3 Sarcoidosis of skin	0.000	0.984	0.015
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.984	0.015
D63.0 Anaemia in neoplastic disease	0.000	0.985	0.015
D84.9 Immunodeficiency, unspecified	0.000	0.985	0.015
D53.9 Nutritional anaemia, unspecified	0.000	0.985	0.015
D83.8 Other common variable immunodeficiencies	0.000	0.985	0.015
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.985	0.015
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.985	0.015
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.985	0.015
D59.9 Acquired haemolytic anaemia, unspecified	0.000	0.985	0.015
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.985	0.015
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.985	0.015
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.985	0.015
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.985	0.015
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.985	0.015
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.985	0.015
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.985	0.015
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.985	0.015
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.985	0.015
L30.9 Dermatitis, unspecified	0.015	0.985	0.000
D59.8 Other acquired haemolytic anaemias	0.000	0.985	0.014
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.000	0.985	0.014
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.000	0.985	0.014
D59.4 Other nonautoimmune haemolytic anaemias	0.000	0.985	0.014
D59.3 Haemolytic-uraemic syndrome	0.000	0.985	0.014
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.000	0.985	0.014
D59.0 Drug-induced autoimmune haemolytic anaemia	0.000	0.985	0.014
D86.8 Sarcoidosis of other and combined sites	0.000	0.985	0.015
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.986	0.014
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.986	0.014
D51.2 Transcobalamin II deficiency	0.000	0.986	0.014
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.986	0.014
D75.1 Secondary polycythaemia	0.013	0.986	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.000	0.986	0.013
D55.8 Other anaemias due to enzyme disorders	0.000	0.986	0.013
D55.3 Anaemia due to disorders of nucleotide metabolism	0.000	0.986	0.013
D55.2 Anaemia due to disorders of glycolytic enzymes	0.000	0.986	0.013
D55.1 Anaemia due to other disorders of glutathione metabolism	0.000	0.986	0.013
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.000	0.986	0.013
D57.8 Other sickle-cell disorders	0.000	0.986	0.013
D57.3 Sickle-cell trait	0.000	0.986	0.013
D57.2 Double heterozygous sickling disorders	0.000	0.986	0.013
D57.1 Sickle-cell anaemia without crisis	0.000	0.986	0.013
D57.0 Sickle-cell anaemia with crisis	0.000	0.986	0.013
D58.0 Hereditary spherocytosis	0.000	0.986	0.013
D83.9 Common variable immunodeficiency, unspecified	0.000	0.987	0.013
D58.8 Other specified hereditary haemolytic anaemias	0.000	0.987	0.013
D58.2 Other haemoglobinopathies	0.000	0.987	0.013
D58.1 Hereditary elliptocytosis	0.000	0.987	0.013
D86.0 Sarcoidosis of lung	0.000	0.987	0.013
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.987	0.013
R30 Pain associated with micturition	0.013	0.987	0.000
D56.9 Thalassaemia, unspecified	0.000	0.987	0.012
D56.8 Other thalassaemias	0.000	0.987	0.012
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.000	0.987	0.012
D56.2 Delta-beta thalassaemia	0.000	0.987	0.012
D56.1 Beta thalassaemia	0.000	0.987	0.012
D56.0 Alpha thalassaemia	0.000	0.987	0.012
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.987	0.012
D58.9 Hereditary haemolytic anaemia, unspecified	0.000	0.988	0.012
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.012	0.988	0.000
S62.61 Fracture of other finger (open)	0.012	0.988	0.000
D75 Other diseases of blood and blood-forming organs	0.011	0.988	0.001
R30.9 Painful micturition, unspecified	0.012	0.988	0.000
D56.3 Thalassaemia trait	0.000	0.989	0.011
D75.9 Disease of blood and blood-forming organs, unspecified	0.011	0.989	0.000
J93 Pneumothorax	0.000	0.989	0.011
R30.1 Vesical tenesmus	0.011	0.989	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.990	0.010
D70-D77 Other diseases of blood and blood-forming organs	0.001	0.990	0.008
C50.8 Overlapping lesion of breast	0.000	0.990	0.010
D63.8 Anaemia in other chronic diseases classified elsewhere	0.000	0.990	0.009
Z83.3 Family history of diabetes mellitus	0.010	0.990	0.000
M16.9 Coxarthrosis, unspecified	0.009	0.991	0.000
D75.0 Familial erythrocytosis	0.008	0.991	0.001
J93.8 Other pneumothorax	0.000	0.991	0.009
D75.8 Other specified diseases of blood and blood-forming organs	0.008	0.991	0.001
C15.9 Oesophagus, unspecified	0.000	0.991	0.009
J93.0 Spontaneous tension pneumothorax	0.000	0.991	0.008
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.008	0.992	0.000
J93.1 Other spontaneous pneumothorax	0.000	0.992	0.008
D75.2 Essential thrombocytosis	0.007	0.992	0.001
Z83 Family history of other specific disorders	0.008	0.992	0.000
G40 Epilepsy	0.008	0.992	0.000
G40.9 Epilepsy, unspecified	0.008	0.992	0.000
L30 Other dermatitis	0.008	0.992	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.992	0.007
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.008	0.992	0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.008	0.992	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.007	0.993	0.000
D74 Methaemoglobinaemia	0.001	0.993	0.006
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.001	0.993	0.006
D71 Functional disorders of polymorphonuclear neutrophils	0.001	0.993	0.006
J90-J94 Other diseases of pleura	0.000	0.993	0.007
J91 Pleural effusion in conditions classified elsewhere	0.000	0.993	0.007
R49.0 Dysphonia	0.007	0.993	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.001	0.993	0.005
D73 Diseases of spleen	0.001	0.993	0.006
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.006	0.993	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.006	0.993	0.000
G40.5 Special epileptic syndromes	0.006	0.994	0.000
D72 Other disorders of white blood cells	0.001	0.994	0.005
L30.8 Other specified dermatitis	0.006	0.994	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.000	0.994	0.006
Z83.1 Family history of other infectious and parasitic diseases	0.006	0.994	0.000
Z83.0 Family history of human immunodeficiency virus [HIV]	0.006	0.994	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.006	0.994	0.000
Z83.6 Family history of diseases of the respiratory system	0.006	0.994	0.000
G40.8 Other epilepsy	0.006	0.994	0.000
L30.5 Pityriasis alba	0.006	0.994	0.000
L30.4 Erythema intertrigo	0.006	0.994	0.000
L30.3 Infective dermatitis	0.006	0.994	0.000
L30.2 Cutaneous autosensitisation	0.006	0.994	0.000
L30.1 Dyshidrosis [pompholyx]	0.006	0.994	0.000
L30.0 Nummular dermatitis	0.006	0.994	0.000
D67 Hereditary factor IX deficiency	0.000	0.994	0.006
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.006	0.994	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.006	0.994	0.000
C15 Malignant neoplasm of oesophagus	0.000	0.994	0.006
Chapter VI Diseases of the nervous system	0.006	0.994	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.002	0.994	0.004
J92 Pleural plaque	0.000	0.994	0.006
G00-G09 Inflammatory diseases of the central nervous system	0.006	0.994	0.000
S62.6 Fracture of other finger	0.006	0.994	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.994	0.005
C15.5 Lower third of oesophagus	0.000	0.994	0.006
C18.7 Sigmoid colon	0.000	0.995	0.005
D73.5 Infarction of spleen	0.001	0.995	0.005
G40.7 Petit mal, unspecified, without grand mal seizures	0.005	0.995	0.000
D74.9 Methaemoglobinaemia, unspecified	0.001	0.995	0.004
D74.8 Other methaemoglobinaemias	0.001	0.995	0.004
D74.0 Congenital methaemoglobinaemia	0.001	0.995	0.004
G70-G73 Diseases of myoneural junction and muscle	0.005	0.995	0.000
E78.5 Hyperlipidaemia, unspecified	0.000	0.995	0.005
T51.0 Ethanol	0.005	0.995	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.005	0.995	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.001	0.995	0.004
D76.1 Haemophagocytic lymphohistiocytosis	0.001	0.995	0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations