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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17393098
log Bayes Factor = 26.5255
Chromosome 14   position 34,025,230  (GRCh37) Explore rs17393098 on Ensembl!
Variant rs17393098 is part of Cluster X0042

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
0.998 0.002 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.997 0.003 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
I21 Acute myocardial infarction
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.993 0.007 0.000
I21.9 Acute myocardial infarction, unspecified
0.989 0.011 0.000
S00-S09 Injuries to the head
0.987 0.013 0.000
I25 Chronic ischaemic heart disease
0.981 0.019 0.000
I63 Cerebral infarction
0.980 0.020 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.978 0.022 0.000
Chapter VI Diseases of the nervous system
0.977 0.023 0.000
C51-C58 Malignant neoplasms of female genital organs
0.976 0.024 0.000
H30-H36 Disorders of choroid and retina
0.973 0.027 0.000
Chapter X Diseases of the respiratory system
0.973 0.027 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.971 0.029 0.000
I42 Cardiomyopathy
0.970 0.030 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.968 0.032 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.967 0.033 0.000
I50 Heart failure
0.967 0.033 0.000
I51 Complications and ill-defined descriptions of heart disease
0.967 0.033 0.000
I49 Other cardiac arrhythmias
0.965 0.035 0.000
S60-S69 Injuries to the wrist and hand
0.963 0.037 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.957 0.043 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.955 0.045 0.000
R50-R69 General symptoms and signs
0.954 0.046 0.000
C78.0 Secondary malignant neoplasm of lung
0.954 0.046 0.000
I42.0 Dilated cardiomyopathy
0.953 0.047 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.952 0.048 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.949 0.051 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.948 0.052 0.000
H25-H28 Disorders of lens
0.948 0.052 0.000
R53 Malaise and fatigue
0.946 0.054 0.000
C78.2 Secondary malignant neoplasm of pleura
0.945 0.055 0.000
R00.2 Palpitations
0.944 0.056 0.000
R00 Abnormalities of heart beat
0.944 0.056 0.000
C78.7 Secondary malignant neoplasm of liver
0.941 0.059 0.000
R47-R49 Symptoms and signs involving speech and voice
0.939 0.061 0.000
I69 Sequelae of cerebrovascular disease
0.937 0.063 0.000
C15-C26 Malignant neoplasms of digestive organs
0.937 0.063 0.000
S01 Open wound of head
0.936 0.064 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.934 0.066 0.000
J95-J99 Other diseases of the respiratory system
0.929 0.071 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.929 0.071 0.000
G90-G99 Other disorders of the nervous system
0.928 0.072 0.000
I25.2 Old myocardial infarction
0.927 0.073 0.000
I47 Paroxysmal tachycardia
0.926 0.074 0.000
H35 Other retinal disorders
0.926 0.074 0.000
Chapter VIII Diseases of the ear and mastoid process
0.925 0.075 0.000
J60-J70 Lung diseases due to external agents
0.922 0.078 0.000
I63.9 Cerebral infarction, unspecified
0.921 0.079 0.000
S62 Fracture at wrist and hand level
0.921 0.079 0.000
I22 Subsequent myocardial infarction
0.920 0.080 0.000
F30-F39 Mood [affective] disorders
0.919 0.081 0.000
W00-W19 Falls
0.919 0.081 0.000
F10.3 Withdrawal state
0.918 0.082 0.000
C56 Malignant neoplasm of ovary
0.917 0.083 0.000
R41.3 Other amnesia
0.917 0.083 0.000
F10.2 Dependence syndrome
0.915 0.085 0.000
G30-G32 Other degenerative diseases of the nervous system
0.915 0.085 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.913 0.087 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.911 0.089 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.909 0.091 0.000
R07 Pain in throat and chest
0.909 0.091 0.000
S02 Fracture of skull and facial bones
0.907 0.093 0.000
I50.0 Congestive heart failure
0.906 0.094 0.000
R07.2 Precordial pain
0.906 0.094 0.000
S10-S19 Injuries to the neck
0.905 0.095 0.000
I51.8 Other ill-defined heart diseases
0.900 0.100 0.000
I61 Intracerebral haemorrhage
0.899 0.101 0.000
H04 Disorders of lachrymal system
0.894 0.106 0.000
C25 Malignant neoplasm of pancreas
0.894 0.106 0.000
H25 Senile cataract
0.893 0.107 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.890 0.110 0.000
S20-S29 Injuries to the thorax
0.887 0.113 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.883 0.117 0.000
I34 Nonrheumatic mitral valve disorders
0.882 0.118 0.000
I69.3 Sequelae of cerebral infarction
0.880 0.120 0.000
C77.3 Axillary and upper limb lymph nodes
0.879 0.121 0.000
H25.0 Senile incipient cataract
0.877 0.123 0.000
C54 Malignant neoplasm of corpus uteri
0.876 0.124 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.876 0.124 0.000
W20-W49 Exposure to inanimate mechanical forces
0.875 0.125 0.000
S01.8 Open wound of other parts of head
0.873 0.127 0.000
H65-H75 Diseases of middle ear and mastoid
0.872 0.128 0.000
R49 Voice disturbances
0.872 0.128 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.871 0.129 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.871 0.129 0.000
S70-S79 Injuries to the hip and thigh
0.870 0.130 0.000
S62.6 Fracture of other finger
0.869 0.131 0.000
C80 Malignant neoplasm without specification of site
0.869 0.131 0.000
Chapter XXII Codes for special purposes
0.869 0.131 0.000
J69 Pneumonitis due to solids and liquids
0.869 0.131 0.000
M50-M54 Other dorsopathies
0.869 0.131 0.000
R01 Cardiac murmurs and other cardiac sounds
0.868 0.132 0.000
S61 Open wound of wrist and hand
0.868 0.132 0.000
S40-S49 Injuries to the shoulder and upper arm
0.868 0.132 0.000
J30-J39 Other diseases of upper respiratory tract
0.868 0.132 0.000
I50.1 Left ventricular failure
0.864 0.136 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.864 0.136 0.000
I24 Other acute ischaemic heart diseases
0.861 0.139 0.000
C25.9 Pancreas, unspecified
0.859 0.141 0.000
J98 Other respiratory disorders
0.856 0.144 0.000
H33 Retinal detachments and breaks
0.854 0.146 0.000
G30 Alzheimer's disease
0.854 0.146 0.000
M51 Other intervertebral disk disorders
0.852 0.148 0.000
I35 Nonrheumatic aortic valve disorders
0.849 0.151 0.000
C77.9 Lymph node, unspecified
0.846 0.154 0.000
C77.2 Intra-abdominal lymph nodes
0.844 0.156 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.841 0.158 0.000
G93 Other disorders of brain
0.841 0.159 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.841 0.159 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.841 0.159 0.000
W13 Fall from, out of or through building or structure
0.840 0.160 0.000
I49.5 Sick sinus syndrome
0.840 0.160 0.000
H43-H45 Disorders of vitreous body and globe
0.839 0.161 0.000
R40 Somnolence, stupor and coma
0.839 0.161 0.000
I31 Other diseases of pericardium
0.838 0.161 0.000
I47.2 Ventricular tachycardia
0.838 0.162 0.000
C18 Malignant neoplasm of colon
0.837 0.163 0.000
H04.2 Epiphora
0.835 0.165 0.000
M51.2 Other specified intervertebral disk displacement
0.833 0.167 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.833 0.167 0.000
I44 Atrioventricular and left bundle-branch block
0.832 0.168 0.000
I49.0 Ventricular fibrillation and flutter
0.831 0.169 0.000
J69.0 Pneumonitis due to food and vomit
0.831 0.169 0.000
S62.60 Fracture of other finger (closed)
0.828 0.172 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.825 0.174 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.825 0.175 0.000
I62 Other nontraumatic intracranial haemorrhage
0.824 0.176 0.000
F31 Bipolar affective disorder
0.823 0.177 0.000
S05 Injury of eye and orbit
0.821 0.179 0.000
C18.7 Sigmoid colon
0.821 0.179 0.000
I49.1 Atrial premature depolarisation
0.816 0.184 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.815 0.185 0.000
I65.2 Occlusion and stenosis of carotid artery
0.813 0.187 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.810 0.190 0.000
R54 Senility
0.810 0.190 0.000
F03 Unspecified dementia
0.809 0.191 0.000
M40-M43 Deforming dorsopathies
0.809 0.191 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.808 0.192 0.000
R01.1 Cardiac murmur, unspecified
0.806 0.194 0.000
C54.1 Endometrium
0.804 0.196 0.000
C79 Secondary malignant neoplasm of other sites
0.802 0.198 0.000
H35.8 Other specified retinal disorders
0.799 0.201 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.799 0.201 0.000
Y57 Other and unspecified drugs and medicaments
0.799 0.201 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.798 0.202 0.000
I49.9 Cardiac arrhythmia, unspecified
0.798 0.202 0.000
R52 Pain, not elsewhere classified
0.796 0.204 0.000
H55-H59 Other disorders of eye and adnexa
0.796 0.204 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.796 0.204 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.796 0.204 0.000
H35.9 Retinal disorder, unspecified
0.796 0.204 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.795 0.205 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.794 0.206 0.000
W25 Contact with sharp glass
0.793 0.207 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.793 0.207 0.000
T91 Sequelae of injuries of neck and trunk
0.792 0.208 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.791 0.209 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.790 0.210 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.790 0.210 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.789 0.211 0.000
S02.1 Fracture of base of skull
0.788 0.212 0.000
F80-F89 Disorders of psychological development
0.788 0.212 0.000
G40-G47 Episodic and paroxysmal disorders
0.787 0.213 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.786 0.214 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.786 0.214 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.786 0.214 0.000
I25.1 Atherosclerotic heart disease
0.786 0.214 0.000
W13.9 Unspecified place
0.784 0.216 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.783 0.217 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.783 0.217 0.000
I49.3 Ventricular premature depolarisation
0.782 0.218 0.000
W18 Other fall on same level
0.782 0.218 0.000
I42.9 Cardiomyopathy, unspecified
0.781 0.219 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.780 0.220 0.000
R61 Hyperhidrosis
0.780 0.220 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.779 0.221 0.000
S01.9 Open wound of head, part unspecified
0.779 0.221 0.000
I34.0 Mitral (valve) insufficiency
0.778 0.222 0.000
I44.7 Left bundle-branch block, unspecified
0.774 0.226 0.000
R47 Speech disturbances, not elsewhere classified
0.772 0.228 0.000
R50 Fever of unknown origin
0.772 0.228 0.000
I46 Cardiac arrest
0.771 0.229 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.771 0.229 0.000
G30.9 Alzheimer's disease, unspecified
0.768 0.232 0.000
S06 Intracranial injury
0.768 0.232 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.767 0.232 0.000
H50 Other strabismus
0.766 0.234 0.000
C73 Malignant neoplasm of thyroid gland
0.766 0.234 0.000
V20-V29 Motorcycle rider injured in transport accident
0.765 0.235 0.000
I45 Other conduction disorders
0.765 0.235 0.000
C50-C50 Malignant neoplasm of breast
0.764 0.236 0.000
I30 Acute pericarditis
0.763 0.237 0.000
S14 Injury of nerves and spinal cord at neck level
0.763 0.237 0.000
Chapter I Certain infectious and parasitic diseases
0.763 0.237 0.000
H90-H95 Other disorders of ear
0.762 0.237 0.000
R49.1 Aphonia
0.762 0.238 0.000
G90 Disorders of autonomic nervous system
0.762 0.238 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.762 0.238 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.761 0.239 0.000
Q00-Q07 Congenital malformations of the nervous system
0.761 0.239 0.000
H35.0 Background retinopathy and retinal vascular changes
0.761 0.239 0.000
F32 Depressive episode
0.761 0.239 0.000
H00 Hordeolum and chalazion
0.760 0.240 0.000
M86-M90 Other osteopathies
0.760 0.240 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.759 0.241 0.000
H53-H54 Visual disturbances and blindness
0.758 0.242 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.758 0.242 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.757 0.243 0.000
F00 Dementia in Alzheimer's disease
0.756 0.244 0.000
V10-V19 Pedal cyclist injured in transport accident
0.756 0.244 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.756 0.244 0.000
D00-D09 In situ neoplasms
0.755 0.245 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.755 0.245 0.000
T66-T78 Other and unspecified effects of external causes
0.755 0.245 0.000
S61.0 Open wound of finger(s) without damage to nail
0.754 0.246 0.000
Y00-Y09 Assault
0.753 0.246 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.753 0.247 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.752 0.248 0.000
M05-M14 Inflammatory polyarthropathies
0.751 0.249 0.000
I35.1 Aortic (valve) insufficiency
0.751 0.249 0.000
H36 Retinal disorders in diseases classified elsewhere
0.751 0.249 0.000
H66 Suppurative and unspecified otitis media
0.751 0.249 0.000
I51.6 Cardiovascular disease, unspecified
0.750 0.250 0.000
S50-S59 Injuries to the elbow and forearm
0.750 0.250 0.000
S12 Fracture of neck
0.749 0.251 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.749 0.251 0.000
Y44 Agents primarily affecting blood constituents
0.749 0.251 0.000
S61.1 Open wound of finger(s) with damage to nail
0.749 0.251 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.746 0.254 0.000
X20-X29 Contact with venomous animals and plants
0.745 0.254 0.000
H35.2 Other proliferative retinopathy
0.745 0.255 0.000
I47.1 Supraventricular tachycardia
0.745 0.255 0.000
J98.1 Pulmonary collapse
0.745 0.255 0.000
H72 Perforation of tympanic membrane
0.744 0.256 0.000
I33 Acute and subacute endocarditis
0.744 0.256 0.000
R68 Other general symptoms and signs
0.744 0.256 0.000
V40-V49 Car occupant injured in transport accident
0.744 0.256 0.000
F11 Mental and behavioural disorders due to use of opioids
0.744 0.256 0.000
H49 Paralytic strabismus
0.743 0.257 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.740 0.260 0.000
F10.4 Withdrawal state with delirium
0.739 0.261 0.000
G70-G73 Diseases of myoneural junction and muscle
0.738 0.262 0.000
R46 Symptoms and signs involving appearance and behaviour
0.738 0.262 0.000
S01.0 Open wound of scalp
0.738 0.262 0.000
I51.9 Heart disease, unspecified
0.736 0.264 0.000
W10 Fall on and from stairs and steps
0.736 0.264 0.000
C34 Malignant neoplasm of bronchus and lung
0.735 0.265 0.000
H02 Other disorders of eyelid
0.735 0.265 0.000
W25.9 Unspecified place
0.735 0.265 0.000
H27 Other disorders of lens
0.734 0.266 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.732 0.268 0.000
G30.0 Alzheimer's disease with early onset
0.732 0.268 0.000
H20 Iridocyclitis
0.732 0.268 0.000
H31 Other disorders of choroid
0.732 0.268 0.000
M41 Scoliosis
0.731 0.269 0.000
H35.5 Hereditary retinal dystrophy
0.731 0.269 0.000
H10-H13 Disorders of conjunctiva
0.731 0.269 0.000
I47.0 Reentry ventricular arrhythmia
0.730 0.270 0.000
J98.8 Other specified respiratory disorders
0.729 0.271 0.000
Y40 Systemic antibiotics
0.728 0.272 0.000
U80 Agent resistant to penicillin and related antibiotics
0.727 0.273 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.727 0.273 0.000
T21 Burn and corrosion of trunk
0.727 0.273 0.000
S02.2 Fracture of nasal bones
0.726 0.274 0.000
C77.4 Inguinal and lower limb lymph nodes
0.726 0.274 0.000
S32 Fracture of lumbar spine and pelvis
0.726 0.274 0.000
I51.0 Cardiac septal defect, acquired
0.725 0.275 0.000
C80.9 Malignant neoplasm, unspecified
0.725 0.275 0.000
S72 Fracture of femur
0.724 0.276 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.724 0.276 0.000
H73 Other disorders of tympanic membrane
0.724 0.276 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.723 0.276 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.723 0.277 0.000
I51.7 Cardiomegaly
0.722 0.278 0.000
H35.4 Peripheral retinal degeneration
0.722 0.278 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.722 0.278 0.000
H35.6 Retinal haemorrhage
0.722 0.278 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.721 0.278 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.721 0.279 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.721 0.279 0.000
H16 Keratitis
0.721 0.279 0.000
V80-V89 Other land transport accidents
0.721 0.279 0.000
I27 Other pulmonary heart diseases
0.719 0.281 0.000
F10.0 Acute intoxication
0.718 0.282 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.718 0.282 0.000
H04.8 Other disorders of lachrymal system
0.717 0.283 0.000
G96 Other disorders of central nervous system
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.717 0.283 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.717 0.283 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.717 0.283 0.000
F30 Manic episode
0.717 0.283 0.000
R57 Shock, not elsewhere classified
0.716 0.283 0.000
Y57.9 Drug or medicament, unspecified
0.717 0.283 0.000
S22.4 Multiple fractures of ribs
0.716 0.284 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.716 0.284 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.716 0.284 0.000
H26 Other cataract
0.716 0.284 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.716 0.284 0.000
H33.0 Retinal detachment with retinal break
0.716 0.284 0.000
R41.0 Disorientation, unspecified
0.715 0.285 0.000
M53 Other dorsopathies, not elsewhere classified
0.715 0.285 0.000
S62.3 Fracture of other metacarpal bone
0.715 0.285 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.715 0.285 0.000
R40.0 Somnolence
0.715 0.285 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.715 0.285 0.000
H21 Other disorders of iris and ciliary body
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.714 0.285 0.000
F70-F79 Mental retardation
0.714 0.285 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.714 0.286 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.714 0.286 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.714 0.286 0.000
W50-W64 Exposure to animate mechanical forces
0.713 0.287 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.713 0.287 0.000
H33.3 Retinal breaks without detachment
0.712 0.288 0.000
X60-X84 Intentional self-harm
0.712 0.288 0.000
Y35-Y36 Legal intervention and operations of war
0.712 0.288 0.000
Y10-Y34 Event of undetermined intent
0.712 0.288 0.000
X85-X99 Assault
0.712 0.288 0.000
X50-X57 Overexertion, travel and privation
0.712 0.288 0.000
X30-X39 Exposure to forces of nature
0.712 0.288 0.000
X10-X19 Contact with heat and hot substances
0.712 0.288 0.000
X00-X09 Exposure to smoke, fire and flames
0.712 0.288 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.712 0.288 0.000
W75-W84 Other accidental threats to breathing
0.712 0.288 0.000
W65-W74 Accidental drowning and submersion
0.712 0.288 0.000
V98-V99 Other and unspecified transport accidents
0.712 0.288 0.000
V95-V97 Air and space transport accidents
0.712 0.288 0.000
V90-V94 Water transport accidents
0.712 0.288 0.000
V70-V79 Bus occupant injured in transport accident
0.712 0.288 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.712 0.288 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.712 0.288 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.712 0.288 0.000
V01-V09 Pedestrian injured in transport accident
0.712 0.288 0.000
R49.0 Dysphonia
0.712 0.288 0.000
R52.2 Other chronic pain
0.712 0.288 0.000
G93.2 Benign intracranial hypertension
0.711 0.288 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.710 0.290 0.000
I24.1 Dressler's syndrome
0.710 0.290 0.000
R45 Symptoms and signs involving emotional state
0.709 0.291 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.709 0.291 0.000
C77.0 Lymph nodes of head, face and neck
0.708 0.292 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.708 0.292 0.000
S08 Traumatic amputation of part of head
0.708 0.292 0.000
S07 Crushing injury of head
0.708 0.292 0.000
S04 Injury of cranial nerves
0.708 0.292 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.708 0.292 0.000
M45-M49 Spondylopathies
0.707 0.293 0.000
M80-M85 Disorders of bone density and structure
0.707 0.293 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.707 0.293 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.707 0.293 0.000
Y52 Agents primarily affecting the cardiovascular system
0.706 0.293 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.706 0.294 0.000
S62.4 Multiple fractures of metacarpal bones
0.706 0.294 0.000
S09 Other and unspecified injuries of head
0.706 0.294 0.000
C17 Malignant neoplasm of small intestine
0.705 0.295 0.000
G93.4 Encephalopathy, unspecified
0.705 0.295 0.000
F34 Persistent mood [affective] disorders
0.705 0.295 0.000
R41.2 Retrograde amnesia
0.705 0.295 0.000
S02.3 Fracture of orbital floor
0.705 0.295 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.704 0.295 0.000
R49.8 Other and unspecified voice disturbances
0.704 0.296 0.000
S02.10 Fracture of base of skull (closed)
0.704 0.296 0.000
I25.6 Silent myocardial ischaemia
0.703 0.296 0.000
I25.4 Coronary artery aneurysm
0.703 0.296 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.703 0.296 0.000
T92 Sequelae of injuries of upper limb
0.703 0.297 0.000
R60 Oedema, not elsewhere classified
0.702 0.297 0.000
H90 Conductive and sensorineural hearing loss
0.702 0.298 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.702 0.298 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.702 0.298 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.702 0.298 0.000
I25.3 Aneurysm of heart
0.702 0.298 0.000
S42 Fracture of shoulder and upper arm
0.702 0.298 0.000
J34 Other disorders of nose and nasal sinuses
0.702 0.298 0.000
S02.6 Fracture of mandible
0.702 0.298 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.701 0.298 0.000
R43 Disturbances of smell and taste
0.701 0.299 0.000
H60-H62 Diseases of external ear
0.701 0.299 0.000
J38.3 Other diseases of vocal cords
0.700 0.299 0.000
F32.9 Depressive episode, unspecified
0.700 0.300 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.700 0.300 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.700 0.300 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.700 0.300 0.000
C51 Malignant neoplasm of vulva
0.700 0.300 0.000
C58 Malignant neoplasm of placenta
0.700 0.300 0.000
C52 Malignant neoplasm of vagina
0.700 0.300 0.000
T91.1 Sequelae of fracture of spine
0.698 0.302 0.000
D03 Melanoma in situ
0.698 0.302 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.698 0.302 0.000
H30 Chorioretinal inflammation
0.698 0.302 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.697 0.303 0.000
C34.1 Upper lobe, bronchus or lung
0.697 0.303 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.696 0.304 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.696 0.304 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.696 0.304 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.696 0.304 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.696 0.304 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.696 0.304 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.696 0.304 0.000
M51.8 Other specified intervertebral disk disorders
0.696 0.304 0.000
I42.8 Other cardiomyopathies
0.695 0.305 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.695 0.305 0.000
I42.6 Alcoholic cardiomyopathy
0.695 0.305 0.000
I42.5 Other restrictive cardiomyopathy
0.695 0.305 0.000
I42.4 Endocardial fibroelastosis
0.695 0.305 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.695 0.305 0.000
J09-J18 Influenza and pneumonia
0.695 0.305 0.000
C25.2 Tail of pancreas
0.695 0.305 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.695 0.305 0.000
S01.2 Open wound of nose
0.695 0.305 0.000
G91 Hydrocephalus
0.693 0.307 0.000
I51.5 Myocardial degeneration
0.693 0.307 0.000
I51.4 Myocarditis, unspecified
0.693 0.307 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.693 0.307 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.693 0.307 0.000
M60-M63 Disorders of muscles
0.693 0.307 0.000
C79.2 Secondary malignant neoplasm of skin
0.692 0.308 0.000
I49.2 Junctional premature depolarisation
0.692 0.308 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.691 0.309 0.000
S65 Injury of blood vessels at wrist and hand level
0.690 0.309 0.000
Q80-Q89 Other congenital malformations
0.689 0.311 0.000
S79 Other and unspecified injuries of hip and thigh
0.688 0.312 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.687 0.313 0.000
I50.9 Heart failure, unspecified
0.687 0.313 0.000
F10.9 Unspecified mental and behavioural disorder
0.686 0.314 0.000
F10.8 Other mental and behavioural disorders
0.686 0.314 0.000
F10.7 Residual and late-onset psychotic disorder
0.686 0.314 0.000
F10.6 Amnesic syndrome
0.686 0.314 0.000
F10.5 Psychotic disorder
0.686 0.314 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.686 0.314 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.686 0.314 0.000
I44.0 Atrioventricular block, first degree
0.686 0.314 0.000
R41.1 Anterograde amnesia
0.685 0.315 0.000
Y43 Primarily systemic agents
0.685 0.315 0.000
S67 Crushing injury of wrist and hand
0.684 0.316 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.684 0.316 0.000
R62 Lack of expected normal physiological development
0.684 0.316 0.000
R64 Cachexia
0.684 0.316 0.000
R58 Haemorrhage, not elsewhere classified
0.684 0.316 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.684 0.316 0.000
J95.8 Other postprocedural respiratory disorders
0.684 0.316 0.000
I31.9 Disease of pericardium, unspecified
0.683 0.317 0.000
W18.3 Sports and athletics area
0.683 0.317 0.000
F41 Other anxiety disorders
0.682 0.318 0.000
H53 Visual disturbances
0.682 0.318 0.000
I36 Nonrheumatic tricuspid valve disorders
0.682 0.318 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.681 0.319 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.680 0.320 0.000
H05 Disorders of orbit
0.680 0.320 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.680 0.320 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.679 0.320 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.679 0.321 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.679 0.321 0.000
T17 Foreign body in respiratory tract
0.678 0.322 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.678 0.322 0.000
S01.7 Multiple open wounds of head
0.677 0.323 0.000
H43 Disorders of vitreous body
0.677 0.323 0.000
G93.5 Compression of brain
0.677 0.323 0.000
G37 Other demyelinating diseases of central nervous system
0.676 0.324 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.676 0.324 0.000
S69 Other and unspecified injuries of wrist and hand
0.676 0.324 0.000
M41.9 Scoliosis, unspecified
0.676 0.324 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.676 0.324 0.000
H66.3 Other chronic suppurative otitis media
0.675 0.325 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.675 0.325 0.000
F31.9 Bipolar affective disorder, unspecified
0.674 0.325 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.674 0.326 0.000
G40 Epilepsy
0.674 0.326 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.673 0.326 0.000
S62.5 Fracture of thumb
0.673 0.327 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.673 0.327 0.000
G93.8 Other specified disorders of brain
0.672 0.328 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.672 0.328 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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