TreeWAS – Variant ID: rs17401966

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I85.9 Oesophageal varices without bleeding	0.268	0.732	0.000
I85 Oesophageal varices	0.160	0.840	0.000
I85.0 Oesophageal varices with bleeding	0.139	0.861	0.000
I31.3 Pericardial effusion (noninflammatory)	0.022	0.978	0.000
N42.8 Other specified disorders of prostate	0.000	0.985	0.015
N42.9 Disorder of prostate, unspecified	0.000	0.985	0.015
N42 Other disorders of prostate	0.000	0.985	0.015
N42.1 Congestion and haemorrhage of prostate	0.000	0.986	0.014
C92.1 Chronic myeloid leukaemia	0.000	0.988	0.012
Z11.0 Special screening examination for intestinal infectious diseases	0.000	0.989	0.011
N42.0 Calculus of prostate	0.000	0.989	0.011
N42.2 Atrophy of prostate	0.000	0.989	0.010
N42.3 Dysplasia of prostate	0.000	0.989	0.010
Z03.1 Observation for suspected malignant neoplasm	0.000	0.991	0.009
C85.1 B-cell lymphoma, unspecified	0.009	0.991	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.008	0.992	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.007	0.993	0.000
Q51.3 Bicornate uterus	0.007	0.993	0.000
C97 Malignant neoplasms of independent (primary) multiple sites	0.000	0.993	0.007
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.007	0.993	0.000
Q51 Congenital malformations of uterus and cervix	0.007	0.993	0.000
Q51.2 Other doubling of uterus	0.007	0.993	0.000
D37.5 Rectum	0.000	0.994	0.006
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.006	0.994	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.006	0.994	0.000
C85.0 Lymphosarcoma	0.006	0.994	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.005	0.995	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.005	0.995	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.005	0.995	0.000
Q51.6 Embryonic cyst of cervix	0.005	0.995	0.000
Q51.5 Agenesis and aplasia of cervix	0.005	0.995	0.000
Q51.4 Unicornate uterus	0.005	0.995	0.000
Q51.0 Agenesis and aplasia of uterus	0.005	0.995	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.005	0.995	0.000
D37.4 Colon	0.000	0.995	0.005
I31 Other diseases of pericardium	0.005	0.995	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.005	0.995	0.000
R41.0 Disorientation, unspecified	0.005	0.995	0.000
R59.1 Generalised enlarged lymph nodes	0.000	0.996	0.004
Q50-Q56 Congenital malformations of genital organs	0.004	0.996	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.004	0.996	0.000
Z04.8 Examination and observation for other specified reasons	0.004	0.996	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.000	0.996	0.004
Q50.5 Embryonic cyst of broad ligament	0.004	0.996	0.000
K51.8 Other ulcerative colitis	0.004	0.996	0.000
T82.1 Mechanical complication of cardiac electronic device	0.000	0.996	0.004
O63.0 Prolonged first stage (of labour)	0.000	0.996	0.004
I44.1 Atrioventricular block, second degree	0.000	0.996	0.004
H21.8 Other specified disorders of iris and ciliary body	0.000	0.996	0.004
D37.2 Small intestine	0.000	0.996	0.004
Q55 Other congenital malformations of male genital organs	0.004	0.996	0.000
I31.0 Chronic adhesive pericarditis	0.004	0.996	0.000
Q52 Other congenital malformations of female genitalia	0.004	0.996	0.000
C92 Myeloid leukaemia	0.000	0.996	0.003
Z29.2 Other prophylactic chemotherapy	0.000	0.996	0.004
D37.6 Liver, gallbladder and bile ducts	0.000	0.996	0.004
D37.3 Appendix	0.000	0.996	0.004
I31.8 Other specified diseases of pericardium	0.003	0.996	0.000
I31.2 Haemopericardium, not elsewhere classified	0.003	0.996	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.996	0.004
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.003	0.996	0.000
Q50.3 Other congenital malformations of ovary	0.003	0.996	0.000
Q50.2 Congenital torsion of ovary	0.003	0.996	0.000
Q50.1 Developmental ovarian cyst	0.003	0.996	0.000
Q50.0 Congenital absence of ovary	0.003	0.996	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.003	0.997	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.003	0.997	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.003	0.997	0.000
C50.2 Upper-inner quadrant of breast	0.003	0.997	0.000
I31.1 Chronic constrictive pericarditis	0.003	0.997	0.000
Q53 Undescended testicle	0.003	0.997	0.000
Q52.5 Fusion of labia	0.003	0.997	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.003	0.997	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.003	0.997	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.000	0.997	0.003
D37.9 Digestive organ, unspecified	0.000	0.997	0.003
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.997	0.003
C92.4 Acute promyelocytic leukaemia	0.000	0.997	0.003
C92.9 Myeloid leukaemia, unspecified	0.000	0.997	0.003
Q55.9 Congenital malformation of male genital organ, unspecified	0.003	0.997	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.003	0.997	0.000
Q55.5 Congenital absence and aplasia of penis	0.003	0.997	0.000
Q55.3 Atresia of vas deferens	0.003	0.997	0.000
Q55.1 Hypoplasia of testis and scrotum	0.003	0.997	0.000
Q55.0 Absence and aplasia of testis	0.003	0.997	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.003	0.997	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.003	0.997	0.000
Q52.7 Other congenital malformations of vulva	0.003	0.997	0.000
Q52.6 Congenital malformation of clitoris	0.003	0.997	0.000
Q52.4 Other congenital malformations of vagina	0.003	0.997	0.000
Q52.3 Imperforate hymen	0.003	0.997	0.000
Q52.2 Congenital rectovaginal fistula	0.003	0.997	0.000
Q52.1 Doubling of vagina	0.003	0.997	0.000
Q52.0 Congenital absence of vagina	0.003	0.997	0.000
Q55.6 Other congenital malformations of penis	0.003	0.997	0.000
C50.9 Breast, unspecified	0.000	0.997	0.003
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.000	0.997	0.003
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.000	0.997	0.003
C92.5 Acute myelomonocytic leukaemia	0.000	0.997	0.003
C92.3 Myeloid sarcoma	0.000	0.997	0.003
C92.2 Subacute myeloid leukaemia	0.000	0.997	0.003
D37.7 Other digestive organs	0.000	0.997	0.003
D37.0 Lip, oral cavity and pharynx	0.000	0.997	0.003
A04.7 Enterocolitis due to Clostridium difficile	0.003	0.997	0.000
Q56.4 Indeterminate sex, unspecified	0.003	0.997	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.003	0.997	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.003	0.997	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.003	0.997	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.003	0.997	0.000
C92.7 Other myeloid leukaemia	0.000	0.997	0.002
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.997	0.003
F22.0 Delusional disorder	0.000	0.997	0.003
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.003	0.997	0.000
Q53.9 Undescended testicle, unspecified	0.002	0.997	0.000
K51 Ulcerative colitis	0.003	0.997	0.000
Q53.2 Undescended testicle, bilateral	0.002	0.997	0.000
Q53.0 Ectopic testis	0.002	0.997	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.003	0.997	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.003	0.997	0.000
F31 Bipolar affective disorder	0.000	0.997	0.003
D37.1 Stomach	0.000	0.997	0.002
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.997	0.002
N95.0 Postmenopausal bleeding	0.003	0.997	0.000
C51.9 Vulva, unspecified	0.002	0.997	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.000	0.998	0.002
Q53.1 Undescended testicle, unilateral	0.002	0.998	0.000
Z34.8 Supervision of other normal pregnancy	0.002	0.998	0.000
K29.0 Acute haemorrhagic gastritis	0.000	0.998	0.002
G43.9 Migraine, unspecified	0.000	0.998	0.002
Q43.8 Other specified congenital malformations of intestine	0.002	0.998	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.000	0.998	0.002
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.998	0.002
Q43.0 Meckel's diverticulum	0.002	0.998	0.000
Q43 Other congenital malformations of intestine	0.002	0.998	0.000
F05.9 Delirium, unspecified	0.002	0.998	0.000
Q54 Hypospadias	0.002	0.998	0.000
H18.9 Disorder of cornea, unspecified	0.002	0.998	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
L29.9 Pruritus, unspecified	0.000	0.998	0.002
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.002	0.998	0.000
S42.10 Fracture of scapula (closed)	0.000	0.998	0.002
C21.1 Anal canal	0.002	0.998	0.000
F31.8 Other bipolar affective disorders	0.000	0.998	0.002
L05.0 Pilonidal cyst with abscess	0.002	0.998	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
K51.1 Ulcerative (chronic) ileocolitis	0.002	0.998	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.000	0.998	0.002
K51.9 Ulcerative colitis, unspecified	0.002	0.998	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.002	0.998	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.002	0.998	0.000
C21.0 Anus, unspecified	0.002	0.998	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.000	0.998	0.002
H21 Other disorders of iris and ciliary body	0.000	0.998	0.002
M25.47 Effusion of joint (Ankle and foot)	0.000	0.998	0.002
D39.1 Ovary	0.002	0.998	0.000
S92.40 Fracture of great toe (closed)	0.000	0.998	0.002
R23.4 Changes in skin texture	0.000	0.998	0.002
K51.4 Pseudopolyposis of colon	0.002	0.998	0.000
S91.1 Open wound of toe(s) without damage to nail	0.000	0.998	0.002
S91 Open wound of ankle and foot	0.000	0.998	0.002
H18.3 Changes in corneal membranes	0.002	0.998	0.000
S93.0 Dislocation of ankle joint	0.000	0.998	0.002
T78.3 Angioneurotic oedema	0.000	0.998	0.002
H06.2 Dysthyroid exophthalmos	0.000	0.998	0.002
H18.5 Hereditary corneal dystrophies	0.002	0.998	0.000
K51.5 Mucosal proctocolitis	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.998	0.002
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.002	0.998	0.000
Q43.7 Persistent cloaca	0.002	0.998	0.000
Q43.6 Congenital fistula of rectum and anus	0.002	0.998	0.000
Q43.5 Ectopic anus	0.002	0.998	0.000
Q43.4 Duplication of intestine	0.002	0.998	0.000
Q43.2 Other congenital functional disorders of colon	0.002	0.998	0.000
Q43.1 Hirschsprung's disease	0.002	0.998	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.002	0.998	0.000
J30.1 Allergic rhinitis due to pollen	0.000	0.998	0.002
D59 Acquired haemolytic anaemia	0.002	0.998	0.000
Q43.3 Congenital malformations of intestinal fixation	0.002	0.998	0.000
Q54.4 Congenital chordee	0.001	0.998	0.000
Q54.3 Hypospadias, perineal	0.001	0.998	0.000
Q54.2 Hypospadias, penoscrotal	0.001	0.998	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.998	0.002
Z45.2 Adjustment and management of vascular access device	0.002	0.998	0.000
Z98.8 Other specified postsurgical states	0.002	0.998	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.998	0.002
H21.0 Hyphaema	0.000	0.998	0.002
L25.9 Unspecified contact dermatitis, unspecified cause	0.002	0.998	0.000
Q54.8 Other hypospadias	0.001	0.998	0.000
S91.3 Open wound of other parts of foot	0.000	0.998	0.002
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.000	0.998	0.002
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.000	0.998	0.002
C92.0 Acute myeloid leukaemia	0.000	0.998	0.002
H21.9 Disorder of iris and ciliary body, unspecified	0.000	0.998	0.002
K86.9 Disease of pancreas, unspecified	0.000	0.998	0.002
F60.6 Anxious [avoidant] personality disorder	0.002	0.998	0.000
H21.2 Degeneration of iris and ciliary body	0.000	0.998	0.002
K86.1 Other chronic pancreatitis	0.000	0.998	0.002
H21.5 Other adhesions and disruptions of iris and ciliary body	0.000	0.998	0.002
I31.9 Disease of pericardium, unspecified	0.002	0.998	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.000	0.998	0.002
S90-S99 Injuries to the ankle and foot	0.000	0.998	0.002
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.998	0.002
S92.4 Fracture of great toe	0.000	0.998	0.002
D59.4 Other nonautoimmune haemolytic anaemias	0.002	0.998	0.000
E53.8 Deficiency of other specified B group vitamins	0.002	0.998	0.000
D59.1 Other autoimmune haemolytic anaemias	0.002	0.998	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.000	0.998	0.002
K51.2 Ulcerative (chronic) proctitis	0.002	0.998	0.000
Q54.1 Hypospadias, penile	0.001	0.998	0.000
S92 Fracture of foot, except ankle	0.000	0.998	0.002
M76.67 Achilles tendinitis (Ankle and foot)	0.002	0.998	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.002	0.998	0.000
Q40.2 Other specified congenital malformations of stomach	0.002	0.998	0.000
S91.7 Multiple open wounds of ankle and foot	0.000	0.998	0.001
S91.2 Open wound of toe(s) with damage to nail	0.000	0.998	0.001
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.000	0.998	0.002
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.000	0.998	0.002
Q40 Other congenital malformations of upper alimentary tract	0.002	0.998	0.000
S91.0 Open wound of ankle	0.000	0.998	0.002
H21.4 Pupillary membranes	0.000	0.998	0.001
H69.9 Eustachian tube disorder, unspecified	0.002	0.998	0.000
O75.8 Other specified complications of labour and delivery	0.000	0.998	0.002
S96.8 Injury of other muscles and tendons at ankle and foot level	0.000	0.998	0.001
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.000	0.998	0.001
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.000	0.998	0.001
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.000	0.998	0.001
S99.9 Unspecified injury of ankle and foot	0.000	0.998	0.002
Z52.3 Bone marrow donor	0.002	0.998	0.000
H18 Other disorders of cornea	0.002	0.998	0.000
D59.8 Other acquired haemolytic anaemias	0.001	0.998	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.001	0.998	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.001	0.998	0.000
D59.3 Haemolytic-uraemic syndrome	0.001	0.998	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.001	0.998	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.001	0.998	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.000	0.998	0.002
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.002	0.998	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.998	0.002
S99 Other and unspecified injuries of ankle and foot	0.000	0.998	0.001
K38.9 Disease of appendix, unspecified	0.000	0.998	0.002
M65.4 Radial styloid tenosynovitis [de Quervain]	0.002	0.998	0.000
S92.3 Fracture of metatarsal bone	0.000	0.998	0.002
T78.4 Allergy, unspecified	0.000	0.998	0.002
S93.4 Sprain and strain of ankle	0.000	0.998	0.001
S93.6 Sprain and strain of other and unspecified parts of foot	0.000	0.998	0.001
S93.5 Sprain and strain of toe(s)	0.000	0.998	0.001
S93.1 Dislocation of toe(s)	0.000	0.998	0.001
Z35.5 Supervision of elderly primigravida	0.000	0.998	0.002
Y95 Nosocomial condition	0.000	0.998	0.002
M65.14 Other infective (teno)synovitis (Hand)	0.001	0.998	0.000
Q39.4 Oesophageal web	0.001	0.998	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.001	0.998	0.000
O66 Other obstructed labour	0.000	0.998	0.002
Q39 Congenital malformations of oesophagus	0.001	0.998	0.000
S97 Crushing injury of ankle and foot	0.000	0.998	0.001
S93.3 Dislocation of other and unspecified parts of foot	0.000	0.998	0.001
C21 Malignant neoplasm of anus and anal canal	0.002	0.998	0.000
S98 Traumatic amputation of ankle and foot	0.000	0.998	0.001
S95 Injury of blood vessels at ankle and foot level	0.000	0.998	0.001
S94 Injury of nerves at ankle and foot level	0.000	0.998	0.001
C71.2 Temporal lobe	0.001	0.998	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.000	0.998	0.001
O46.8 Other antepartum haemorrhage	0.001	0.998	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.999	0.001
T78.2 Anaphylactic shock, unspecified	0.000	0.999	0.001
T91.3 Sequelae of injury of spinal cord	0.000	0.999	0.001
S92.30 Fracture of metatarsal bone (closed)	0.000	0.999	0.001
G54.4 Lumbosacral root disorders, not elsewhere classified	0.001	0.999	0.000
O66.4 Failed trial of labour, unspecified	0.000	0.999	0.001
Q40.8 Other specified congenital malformations of upper alimentary tract	0.001	0.999	0.000
Q54.0 Hypospadias, balanic	0.001	0.999	0.000
S92.9 Fracture of foot, unspecified	0.000	0.999	0.001
S92.1 Fracture of talus	0.000	0.999	0.001
S93.2 Rupture of ligaments at ankle and foot level	0.000	0.999	0.001
C83 Diffuse non-Hodgkin's lymphoma	0.001	0.999	0.000
D39.7 Other female genital organs	0.001	0.999	0.000
H53.0 Amblyopia ex anopsia	0.000	0.999	0.001
H61.8 Other specified disorders of external ear	0.001	0.999	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.001	0.999	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.001	0.999	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.001	0.999	0.000
Q44.4 Choledochal cyst	0.001	0.999	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.001	0.999	0.000
H18.7 Other corneal deformities	0.001	0.999	0.000
Q45 Other congenital malformations of digestive system	0.001	0.999	0.000
F11.2 Dependence syndrome	0.001	0.999	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.999	0.001
Q40.1 Congenital hiatus hernia	0.001	0.999	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.001	0.999	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.001	0.999	0.000
Q54.9 Hypospadias, unspecified	0.001	0.999	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.999	0.001
S92.2 Fracture of other tarsal bone(s)	0.000	0.999	0.001
S99.7 Multiple injuries of ankle and foot	0.000	0.999	0.001
F22 Persistent delusional disorders	0.000	0.999	0.001
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.001	0.999	0.000
T78 Adverse effects, not elsewhere classified	0.000	0.999	0.001
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.000	0.999	0.001
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.001	0.999	0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.001	0.999	0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.001	0.999	0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.001	0.999	0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.001	0.999	0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.001	0.999	0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.001	0.999	0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.001	0.999	0.000
S92.31 Fracture of metatarsal bone (open)	0.000	0.999	0.001
S93.40 Sprain of unspecified ligament of ankle	0.000	0.999	0.001
C83.7 Burkitt's tumour	0.001	0.999	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.001	0.999	0.000
H18.2 Other corneal oedema	0.001	0.999	0.000
I37.1 Pulmonary valve insufficiency	0.000	0.999	0.001
M89.86 Other specified disorders of bone (Lower leg)	0.000	0.999	0.001
G97.0 Cerebrospinal fluid leak from spinal puncture	0.001	0.999	0.000
O66.9 Obstructed labour, unspecified	0.000	0.999	0.001
O66.8 Other specified obstructed labour	0.000	0.999	0.001
O66.3 Obstructed labour due to other abnormalities of foetus	0.000	0.999	0.001
O66.1 Obstructed labour due to locked twins	0.000	0.999	0.001
Q39.9 Congenital malformation of oesophagus, unspecified	0.001	0.999	0.000
Q39.8 Other congenital malformations of oesophagus	0.001	0.999	0.000
Q39.5 Congenital dilatation of oesophagus	0.001	0.999	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.001	0.999	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.001	0.999	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.001	0.999	0.000
Q39.0 Atresia of oesophagus without fistula	0.001	0.999	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.000	0.999	0.001
S97.1 Crushing injury of toe(s)	0.000	0.999	0.001
S97.0 Crushing injury of ankle	0.000	0.999	0.001
Y57.8 Other drugs and medicaments	0.001	0.999	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.000	0.999	0.001
C21.2 Cloacogenic zone	0.001	0.999	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.000	0.999	0.001
M75.3 Calcific tendinitis of shoulder	0.001	0.999	0.000
S92.7 Multiple fractures of foot	0.000	0.999	0.001
S92.5 Fracture of other toe	0.000	0.999	0.001
S94.9 Injury of unspecified nerve at ankle and foot level	0.000	0.999	0.001
S94.8 Injury of other nerves at ankle and foot level	0.000	0.999	0.001
S94.7 Injury of multiple nerves at ankle and foot level	0.000	0.999	0.001
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.000	0.999	0.001
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.000	0.999	0.001
S94.1 Injury of medial plantar nerve	0.000	0.999	0.001
S94.0 Injury of lateral plantar nerve	0.000	0.999	0.001
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.000	0.999	0.001
S95.8 Injury of other blood vessels at ankle and foot level	0.000	0.999	0.001
S95.7 Injury of multiple blood vessels at ankle and foot level	0.000	0.999	0.001
S95.2 Injury of dorsal vein of foot	0.000	0.999	0.001
S95.1 Injury of plantar artery of foot	0.000	0.999	0.001
S95.0 Injury of dorsal artery of foot	0.000	0.999	0.001
S98.4 Traumatic amputation of foot, level unspecified	0.000	0.999	0.001
S98.3 Traumatic amputation of other parts of foot	0.000	0.999	0.001
S98.2 Traumatic amputation of two or more toes	0.000	0.999	0.001
S98.1 Traumatic amputation of one toe	0.000	0.999	0.001
S98.0 Traumatic amputation of foot at ankle level	0.000	0.999	0.001
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.999	0.001
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.001	0.999	0.000
A87.9 Viral meningitis, unspecified	0.000	0.999	0.001
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.001	0.999	0.000
G61.8 Other inflammatory polyneuropathies	0.001	0.999	0.000
G62.8 Other specified polyneuropathies	0.001	0.999	0.000
H18.6 Keratoconus	0.001	0.999	0.000
M47.1 Other spondylosis with myelopathy	0.000	0.999	0.001
S92.11 Fracture of talus (open)	0.000	0.999	0.001
S92.41 Fracture of great toe (open)	0.000	0.999	0.001
S92.91 Fracture of foot, unspecified (open)	0.000	0.999	0.001
S92.90 Fracture of foot, unspecified (closed)	0.000	0.999	0.001
C71.0 Cerebrum, except lobes and ventricles	0.001	0.999	0.000
C83.6 Undifferentiated (diffuse)	0.001	0.999	0.000
C83.5 Lymphoblastic (diffuse)	0.001	0.999	0.000
C83.4 Immunoblastic (diffuse)	0.001	0.999	0.000
C83.2 Mixed small and large cell (diffuse)	0.001	0.999	0.000
H18.8 Other specified disorders of cornea	0.001	0.999	0.000
H18.1 Bullous keratopathy	0.001	0.999	0.000
K52.1 Toxic gastro-enteritis and colitis	0.001	0.999	0.000
Q45.8 Other specified congenital malformations of digestive system	0.001	0.999	0.000
R30.9 Painful micturition, unspecified	0.001	0.999	0.000
S92.0 Fracture of calcaneus	0.000	0.999	0.001
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.001	0.999	0.000
G61 Inflammatory polyneuropathy	0.001	0.999	0.000
S90 Superficial injury of ankle and foot	0.000	0.999	0.001
S92.10 Fracture of talus (closed)	0.000	0.999	0.001
C83.1 Small cleaved cell (diffuse)	0.001	0.999	0.000
F22.9 Persistent delusional disorder, unspecified	0.000	0.999	0.001
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.999	0.001
F64.0 Transsexualism	0.001	0.999	0.000
G62.1 Alcoholic polyneuropathy	0.001	0.999	0.000
H18.4 Corneal degeneration	0.001	0.999	0.000
Q39.6 Diverticulum of oesophagus	0.001	0.999	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.001	0.999	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.001	0.999	0.000
Q45.2 Congenital pancreatic cyst	0.001	0.999	0.000
Q45.1 Annular pancreas	0.001	0.999	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.001	0.999	0.000
Q61.5 Medullary cystic kidney	0.000	0.999	0.001
Q89.2 Congenital malformations of other endocrine glands	0.000	0.999	0.001
S01.1 Open wound of eyelid and periocular area	0.000	0.999	0.001
G62 Other polyneuropathies	0.001	0.999	0.000
M25.54 Pain in joint (Hand)	0.000	0.999	0.001
C21.8 Overlapping lesion of rectum, anus and anal canal	0.001	0.999	0.000
C71.8 Overlapping lesion of brain	0.001	0.999	0.000
J86.9 Pyothorax without fistula	0.000	0.999	0.001
Q38.1 Ankyloglossia	0.001	0.999	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.001	0.999	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.001	0.999	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.001	0.999	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.001	0.999	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.001	0.999	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.001	0.999	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.001	0.999	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.001	0.999	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.001	0.999	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.001	0.999	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.001	0.999	0.000
T78.9 Adverse effect, unspecified	0.000	0.999	0.001
Q38 Other congenital malformations of tongue, mouth and pharynx	0.001	0.999	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.000	0.999	0.001
F22.8 Other persistent delusional disorders	0.000	0.999	0.001
G62.0 Drug-induced polyneuropathy	0.001	0.999	0.000
O66.2 Obstructed labour due to unusually large foetus	0.000	0.999	0.001
Q44.7 Other congenital malformations of liver	0.001	0.999	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.001	0.999	0.000
Q44.2 Atresia of bile ducts	0.001	0.999	0.000
Q44.1 Other congenital malformations of gallbladder	0.001	0.999	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.001	0.999	0.000
Z71.9 Counselling, unspecified	0.000	0.999	0.001
G54.0 Brachial plexus disorders	0.001	0.999	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.001	0.999	0.000
Q61.3 Polycystic kidney, unspecified	0.000	0.999	0.001
S92.71 Multiple fractures of foot (open)	0.000	0.999	0.001
C83.0 Small cell (diffuse)	0.001	0.999	0.000
D44.0 Thyroid gland	0.001	0.999	0.000
H18.0 Corneal pigmentations and deposits	0.001	0.999	0.000
L93.0 Discoid lupus erythematosus	0.000	0.999	0.001
Q44.5 Other congenital malformations of bile ducts	0.001	0.999	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.000	0.999	0.001
M47.19 Other spondylosis with myelopathy (Site unspecified)	0.000	0.999	0.001
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M47.17 Other spondylosis with myelopathy (Lumbosacral region)	0.000	0.999	0.001
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)	0.000	0.999	0.001
M47.14 Other spondylosis with myelopathy (Thoracic region)	0.000	0.999	0.001
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)	0.000	0.999	0.001
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)	0.000	0.999	0.001
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)	0.000	0.999	0.001
C24.1 Ampulla of Vater	0.001	0.999	0.000
D39.9 Female genital organ, unspecified	0.001	0.999	0.000
D39.2 Placenta	0.001	0.999	0.000
K38.8 Other specified diseases of appendix	0.000	0.999	0.001
S99.8 Other specified injuries of ankle and foot	0.000	0.999	0.001
Z52.8 Donor of other organs and tissues	0.001	0.999	0.000
S92.01 Fracture of calcaneus (open)	0.000	0.999	0.001
S92.51 Fracture of other toe (open)	0.000	0.999	0.001
C83.3 Large cell (diffuse)	0.001	0.999	0.000
D68.5 Primary Thrombophilia	0.001	0.999	0.000
G61.1 Serum neuropathy	0.001	0.999	0.000
G62.2 Polyneuropathy due to other toxic agents	0.001	0.999	0.000
Q38.8 Other congenital malformations of pharynx	0.001	0.999	0.000
Q38.6 Other congenital malformations of mouth	0.001	0.999	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.000	0.999	0.001
S90.2 Contusion of toe(s) with damage to nail	0.000	0.999	0.001
S90.1 Contusion of toe(s) without damage to nail	0.000	0.999	0.001
Y91.9 Alcohol involvement, not otherwise specified	0.000	0.999	0.001
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
Q38.4 Congenital malformations of salivary glands and ducts	0.001	0.999	0.000
Q38.3 Other congenital malformations of tongue	0.001	0.999	0.000
Q38.2 Macroglossia	0.001	0.999	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.001	0.999	0.000
S90.8 Other superficial injuries of ankle and foot	0.000	0.999	0.001
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.999	0.001
C24.9 Biliary tract, unspecified	0.001	0.999	0.000
D21.2 Connective and other soft tissue of lower limb, including hip	0.000	0.999	0.001
D48.7 Other specified sites	0.001	0.999	0.000
K60.1 Chronic anal fissure	0.000	0.999	0.001
R30.0 Dysuria	0.001	0.999	0.000
S90.0 Contusion of ankle	0.000	0.999	0.001
C71 Malignant neoplasm of brain	0.001	0.999	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.000	0.999	0.001
M40.24 Other and unspecified kyphosis (Thoracic region)	0.001	0.999	0.000
D38.1 Trachea, bronchus and lung	0.001	0.999	0.000
G61.0 Guillain-Barre syndrome	0.001	0.999	0.000
I49.5 Sick sinus syndrome	0.000	0.999	0.001
M65.1 Other infective (teno)synovitis	0.001	0.999	0.000
S27.0 Traumatic pneumothorax	0.000	0.999	0.001
Y42.0 Glucocorticoids and synthetic analogs	0.000	0.999	0.001
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.001	0.999	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.001	0.999	0.000
O62.2 Other uterine inertia	0.000	0.999	0.001
S90.3 Contusion of other and unspecified parts of foot	0.000	0.999	0.001
M25.43 Effusion of joint (Forearm)	0.000	0.999	0.001
S92.70 Multiple fractures of foot (closed)	0.000	0.999	0.001
C71.6 Cerebellum	0.001	0.999	0.000
C71.5 Cerebral ventricle	0.001	0.999	0.000
D39.0 Uterus	0.001	0.999	0.000
D89.1 Cryoglobulinaemia	0.001	0.999	0.000
G43.8 Other migraine	0.000	0.999	0.001
G45.3 Amaurosis fugax	0.001	0.999	0.000
H69.8 Other specified disorders of Eustachian tube	0.001	0.999	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.001	0.999	0.000
S82.31 Fracture of lower end of tibia (open)	0.001	0.999	0.000
B02.3 Zoster ocular disease	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations