TreeWAS – Variant ID: rs17429847

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
Chapter XI Diseases of the digestive system	0.999	0.001
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.997	0.003
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.996	0.004
E65-E68 Obesity and other hyperalimentation	0.996	0.004
Chapter XV Pregnancy, childbirth and the puerperium	0.994	0.006
E70-E90 Metabolic disorders	0.993	0.007
E66 Obesity	0.993	0.007
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.992	0.008
Z90 Acquired absence of organs, not elsewhere classified	0.991	0.009
Chapter XXI Factors influencing health status and contact with health services	0.990	0.010
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.985	0.015
M70-M79 Other soft tissue disorders	0.985	0.015
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.984	0.016
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.983	0.017
Z90.7 Acquired absence of genital organ(s)	0.977	0.023
K50-K52 Noninfective enteritis and colitis	0.976	0.024
E66.8 Other obesity	0.972	0.028
Chapter II Neoplasms	0.972	0.028
K50 Crohn's disease [regional enteritis]	0.969	0.031
Z90.1 Acquired absence of breast(s)	0.969	0.031
E78.5 Hyperlipidaemia, unspecified	0.969	0.031
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.968	0.032
S80-S89 Injuries to the knee and lower leg	0.968	0.032
M75 Shoulder lesions	0.968	0.032
K04 Diseases of pulp and periapical tissues	0.966	0.034
Z90.4 Acquired absence of other parts of digestive tract	0.964	0.036
E66.9 Obesity, unspecified	0.964	0.036
M05-M14 Inflammatory polyarthropathies	0.962	0.038
Chapter XX External causes of morbidity and mortality	0.961	0.039
Chapter XIV Diseases of the genitourinary system	0.945	0.055
Chapter VI Diseases of the nervous system	0.943	0.057
O60-O75 Complications of labour and delivery	0.943	0.057
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.942	0.058
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.937	0.063
K83 Other diseases of biliary tract	0.937	0.063
E00-E07 Disorders of thyroid gland	0.934	0.066
Chapter XII Diseases of the skin and subcutaneous tissue	0.929	0.071
K02 Dental caries	0.929	0.071
Z93 Artificial opening status	0.928	0.072
K50.9 Crohn's disease, unspecified	0.926	0.074
C64-C68 Malignant neoplasms of urinary tract	0.924	0.076
K04.7 Periapical abscess without sinus	0.916	0.084
Z92 Personal history of medical treatment	0.914	0.086
Z40-Z54 Persons encountering health services for specific procedures and health care	0.913	0.087
Z92.1 Personal history of long-term (current) use of anticoagulants	0.912	0.088
N25-N29 Other disorders of kidney and ureter	0.911	0.089
M75.0 Adhesive capsulitis of shoulder	0.906	0.094
M80-M85 Disorders of bone density and structure	0.904	0.096
Chapter V Mental and behavioural disorders	0.903	0.097
S80 Superficial injury of lower leg	0.901	0.099
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.898	0.102
C67 Malignant neoplasm of bladder	0.895	0.105
Z90.2 Acquired absence of lung [part of]	0.893	0.107
O46 Antepartum haemorrhage, not elsewhere classified	0.893	0.107
E78.0 Pure hypercholesterolaemia	0.889	0.111
N28 Other disorders of kidney and ureter, not elsewhere classified	0.887	0.113
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.883	0.117
E50-E64 Other nutritional deficiencies	0.883	0.117
M13 Other arthritis	0.882	0.118
L40-L45 Papulosquamous disorders	0.882	0.118
Z80 Family history of malignant neoplasm	0.879	0.121
K65-K67 Diseases of peritoneum	0.878	0.122
N99-N99 Other disorders of the genitourinary system	0.877	0.123
M06 Other rheumatoid arthritis	0.876	0.124
S82 Fracture of lower leg, including ankle	0.876	0.124
E83 Disorders of mineral metabolism	0.875	0.125
O36 Maternal care for other known or suspected foetal problems	0.874	0.126
K02.9 Dental caries, unspecified	0.873	0.127
K83.1 Obstruction of bile duct	0.872	0.128
K11 Diseases of salivary glands	0.870	0.130
K50.1 Crohn's disease of large intestine	0.868	0.132
D37-D48 Neoplasms of uncertain or unknown behaviour	0.863	0.137
E04 Other non-toxic goitre	0.863	0.137
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.861	0.139
C50-C50 Malignant neoplasm of breast	0.860	0.140
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.858	0.142
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.856	0.144
L40 Psoriasis	0.854	0.146
K50.8 Other Crohn's disease	0.854	0.146
N28.1 Cyst of kidney, acquired	0.850	0.150
M75.5 Bursitis of shoulder	0.848	0.152
T36-T50 Poisoning by drugs, medicaments and biological substances	0.845	0.155
G40-G47 Episodic and paroxysmal disorders	0.841	0.159
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.841	0.159
O48 Prolonged pregnancy	0.839	0.161
L80-L99 Other disorders of the skin and subcutaneous tissue	0.838	0.162
E20-E35 Disorders of other endocrine glands	0.837	0.163
E53 Deficiency of other B group vitamins	0.837	0.163
E05 Thyrotoxicosis [hyperthyroidism]	0.836	0.164
M77 Other enthesopathies	0.836	0.164
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.836	0.164
E89.0 Postprocedural hypothyroidism	0.829	0.171
O46.9 Antepartum haemorrhage, unspecified	0.828	0.172
Z42 Follow-up care involving plastic surgery	0.828	0.172
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.828	0.172
Z41 Procedures for purposes other than remedying health state	0.828	0.172
K86 Other diseases of pancreas	0.826	0.174
Y57 Other and unspecified drugs and medicaments	0.824	0.176
O32 Maternal care for known or suspected malpresentation of foetus	0.821	0.179
S40-S49 Injuries to the shoulder and upper arm	0.820	0.179
O63 Long labour	0.820	0.180
M75.2 Bicipital tendinitis	0.820	0.180
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.820	0.180
Z53 Persons encountering health services for specifie procedures, not carried out	0.819	0.181
Z93.3 Colostomy status	0.818	0.182
K35-K38 Diseases of appendix	0.818	0.182
E83.5 Disorders of calcium metabolism	0.817	0.183
S10-S19 Injuries to the neck	0.814	0.186
Z53.0 Procedure not carried out because of contraindication	0.812	0.188
K09 Cysts of oral region, not elsewhere classified	0.809	0.191
O94-O99 Other obstetric conditions, not elsewhere classified	0.809	0.191
G30-G32 Other degenerative diseases of the nervous system	0.809	0.191
M13.9 Arthritis, unspecified	0.807	0.193
Z93.2 Ileostomy status	0.806	0.194
S70-S79 Injuries to the hip and thigh	0.806	0.194
G47 Sleep disorders	0.805	0.195
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.804	0.195
E53.8 Deficiency of other specified B group vitamins	0.804	0.196
K04.8 Radicular cyst	0.804	0.196
M75.4 Impingement syndrome of shoulder	0.803	0.197
Z93.6 Other artificial openings of urinary tract status	0.802	0.198
M05 Seropositive rheumatoid arthritis	0.801	0.199
Y52 Agents primarily affecting the cardiovascular system	0.800	0.200
G20-G26 Extrapyramidal and movement disorders	0.797	0.203
O75 Other complications of labour and delivery, not elsewhere classified	0.796	0.204
L82 Seborrhoeic keratosis	0.795	0.205
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.794	0.206
C91 Lymphoid leukaemia	0.794	0.206
C67.1 Dome of bladder	0.792	0.208
Y43 Primarily systemic agents	0.791	0.209
Z90.6 Acquired absence of other parts of urinary tract	0.790	0.210
E73 Lactose intolerance	0.787	0.213
O36.8 Maternal care for other specified foetal problems	0.787	0.213
C67.3 Anterior wall of bladder	0.786	0.214
M84 Disorders of continuity of bone	0.786	0.214
Z47 Other orthopaedic follow-up care	0.785	0.215
K04.5 Chronic apical periodontitis	0.784	0.216
K83.0 Cholangitis	0.782	0.218
C51-C58 Malignant neoplasms of female genital organs	0.781	0.219
C50 Malignant neoplasm of breast	0.781	0.219
M75.3 Calcific tendinitis of shoulder	0.780	0.220
S00-S09 Injuries to the head	0.780	0.220
E04.2 Non-toxic multinodular goitre	0.780	0.220
S82.2 Fracture of shaft of tibia	0.779	0.220
K66 Other disorders of peritoneum	0.779	0.220
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.779	0.221
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.778	0.222
O34 Maternal care for known or suspected abnormality of pelvic organs	0.777	0.223
K83.8 Other specified diseases of biliary tract	0.777	0.223
Z80.4 Family history of malignant neoplasm of genital organs	0.777	0.223
K00 Disorders of tooth development and eruption	0.777	0.223
O62 Abnormalities of forces of labour	0.776	0.224
C83 Diffuse non-Hodgkin's lymphoma	0.775	0.225
D00-D09 In situ neoplasms	0.774	0.225
N17-N19 Renal failure	0.773	0.227
Z97 Presence of other devices	0.772	0.228
O69 Labour and delivery complicated by umbilical cord complications	0.770	0.230
S80.0 Contusion of knee	0.768	0.232
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.766	0.234
K13 Other diseases of lip and oral mucosa	0.766	0.234
O66 Other obstructed labour	0.766	0.234
K05 Gingivitis and periodontal diseases	0.765	0.235
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.765	0.235
L40.9 Psoriasis, unspecified	0.764	0.236
M00-M03 Infectious arthropathies	0.764	0.236
Z90.3 Acquired absence of part of stomach	0.764	0.236
M71 Other bursopathies	0.762	0.238
M06.9 Rheumatoid arthritis, unspecified	0.762	0.238
K11.2 Sialoadenitis	0.761	0.238
E40-E46 Malnutrition	0.760	0.240
L40.5 Arthropathic psoriasis	0.758	0.242
C67.5 Bladder neck	0.758	0.242
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.755	0.245
O41 Other disorders of amniotic fluid and membranes	0.755	0.245
T15-T19 Effects of foreign body entering through natural orifice	0.754	0.246
K06 Other disorders of gingiva and edentulous alveolar ridge	0.754	0.246
G70-G73 Diseases of myoneural junction and muscle	0.754	0.246
S82.8 Fractures of other parts of lower leg	0.752	0.248
Chapter XXII Codes for special purposes	0.751	0.249
S80.9 Superficial injury of lower leg, unspecified	0.751	0.249
W20-W49 Exposure to inanimate mechanical forces	0.750	0.250
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.750	0.250
K04.6 Periapical abscess with sinus	0.748	0.252
M81 Osteoporosis without pathological fracture	0.747	0.253
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.747	0.253
N28.8 Other specified disorders of kidney and ureter	0.746	0.253
K50.0 Crohn's disease of small intestine	0.745	0.255
O73 Retained placenta and membranes, without haemorrhage	0.745	0.255
S80.8 Other superficial injuries of lower leg	0.743	0.257
Y57.9 Drug or medicament, unspecified	0.743	0.257
K10 Other diseases of jaws	0.742	0.258
M06.0 Seronegative rheumatoid arthritis	0.742	0.258
X50-X57 Overexertion, travel and privation	0.742	0.258
C88 Malignant immunoproliferative diseases	0.742	0.258
S60-S69 Injuries to the wrist and hand	0.741	0.259
G47.3 Sleep apnoea	0.741	0.259
T92 Sequelae of injuries of upper limb	0.739	0.261
E05.0 Thyrotoxicosis with diffuse goitre	0.739	0.261
Z92.8 Personal history of other medical treatment	0.736	0.264
Y00-Y09 Assault	0.736	0.264
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.735	0.265
W50-W64 Exposure to animate mechanical forces	0.734	0.266
G80-G83 Cerebral palsy and other paralytic syndromes	0.734	0.266
Q20-Q28 Congenital malformations of the circulatory system	0.734	0.266
Z43 Attention to artificial openings	0.733	0.267
M65-M68 Disorders of synovium and tendon	0.732	0.268
M76 Enthesopathies of lower limb, excluding foot	0.732	0.268
C67.4 Posterior wall of bladder	0.732	0.268
Y60-Y69 Misadventures to patients during surgical and medical care	0.730	0.269
O47 False labour	0.730	0.270
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.730	0.270
K85 Acute pancreatitis	0.728	0.272
V20-V29 Motorcycle rider injured in transport accident	0.728	0.272
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.727	0.273
L97 Ulcer of lower limb, not elsewhere classified	0.726	0.274
C01 Malignant neoplasm of base of tongue	0.725	0.275
K82 Other diseases of gallbladder	0.724	0.276
C50.2 Upper-inner quadrant of breast	0.723	0.277
Z90.0 Acquired absence of part of head and neck	0.721	0.279
M91-M94 Chondropathies	0.721	0.279
L60-L75 Disorders of skin appendages	0.720	0.280
M70 Soft tissue disorders related to use, overuse and pressure	0.720	0.280
M13.94 Arthritis, unspecified (Hand)	0.720	0.280
Chapter VII Diseases of the eye and adnexa	0.719	0.281
F30-F39 Mood [affective] disorders	0.719	0.281
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M60-M63 Disorders of muscles	0.715	0.285
K02.8 Other dental caries	0.715	0.285
X60-X84 Intentional self-harm	0.714	0.286
Z49 Care involving dialysis	0.714	0.286
T33-T35 Frostbite	0.714	0.286
T26-T28 Burns and corrosions confined to eye and internal organs	0.714	0.286
T20-T25 Burns and corrosions of external body surface, specified by site	0.714	0.286
T00-T07 Injuries involving multiple body regions	0.714	0.286
E67 Other hyperalimentation	0.714	0.286
E68 Sequelae of hyperalimentation	0.714	0.286
E65 Localised adiposity	0.714	0.286
O35 Maternal care for known or suspected foetal abnormality and damage	0.713	0.287
K66.0 Peritoneal adhesions	0.713	0.287
O85-O92 Complications predominantly related to the puerperium	0.713	0.287
E85 Amyloidosis	0.712	0.288
E84 Cystic fibrosis	0.712	0.288
E79 Disorders of purine and pyrimidine metabolism	0.712	0.288
E77 Disorders of glycoprotein metabolism	0.712	0.288
E76 Disorders of glycosaminoglycan metabolism	0.712	0.288
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.712	0.288
E74 Other disorders of carbohydrate metabolism	0.712	0.288
E72 Other disorders of amino-acid metabolism	0.712	0.288
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.712	0.288
E70 Disorders of aromatic amino-acid metabolism	0.712	0.288
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.712	0.288
E66.2 Extreme obesity with alveolar hypoventilation	0.712	0.288
E66.1 Drug-induced obesity	0.712	0.288
E66.0 Obesity due to excess calories	0.712	0.288
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.712	0.288
K03 Other diseases of hard tissues of teeth	0.711	0.289
E04.9 Non-toxic goitre, unspecified	0.711	0.289
S82.20 Fracture of shaft of tibia (closed)	0.711	0.289
N99.4 Postprocedural pelvic peritoneal adhesions	0.711	0.289
K36 Other appendicitis	0.710	0.290
N70-N77 Inflammatory diseases of female pelvic organs	0.709	0.291
Z48 Other surgical follow-up care	0.709	0.291
V80-V89 Other land transport accidents	0.709	0.291
Z80.8 Family history of malignant neoplasm of other organs or systems	0.709	0.291
F00-F09 Organic, including symptomatic, mental disorders	0.708	0.292
F10 Mental and behavioural disorders due to use of alcohol	0.707	0.293
Z89 Acquired absence of limb	0.706	0.293
Z84 Family history of other conditions	0.706	0.293
Z81 Family history of mental and behavioural disorders	0.706	0.293
M73 Soft tissue disorders in diseases classified elsewhere	0.706	0.294
E78.8 Other disorders of lipoprotein metabolism	0.706	0.294
E78.6 Lipoprotein deficiency	0.706	0.294
E78.4 Other hyperlipidaemia	0.706	0.294
E78.3 Hyperchylomicronaemia	0.706	0.294
E78.2 Mixed hyperlipidaemia	0.706	0.294
E78.1 Pure hyperglyceridaemia	0.706	0.294
M13.97 Arthritis, unspecified (Ankle and foot)	0.706	0.294
G47.9 Sleep disorder, unspecified	0.706	0.294
Z42.0 Follow-up care involving plastic surgery of head and neck	0.705	0.294
F60-F69 Disorders of adult personality and behaviour	0.705	0.295
O45 Premature separation of placenta [abruptio placentae]	0.705	0.295
O44 Placenta praevia	0.705	0.295
O43 Placental disorders	0.705	0.295
O33 Maternal care for known or suspected disproportion	0.705	0.295
O31 Complications specific to multiple gestation	0.705	0.295
O40 Polyhydramnios	0.705	0.295
G30 Alzheimer's disease	0.703	0.297
N17 Acute renal failure	0.703	0.297
L40.8 Other psoriasis	0.703	0.297
O68 Labour and delivery complicated by foetal stress [distress]	0.702	0.297
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.702	0.298
N40-N51 Diseases of male genital organs	0.702	0.298
O20-O29 Other maternal disorders predominantly related to pregnancy	0.699	0.301
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.699	0.301
S42 Fracture of shoulder and upper arm	0.698	0.302
Y45.2 Propionic acid derivatives	0.697	0.303
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.697	0.303
C40-C41 Malignant neoplasms of bone and articular cartilage	0.697	0.303
N00-N08 Glomerular diseases	0.697	0.303
S81 Open wound of lower leg	0.696	0.304
K70-K77 Diseases of liver	0.695	0.305
S01 Open wound of head	0.695	0.305
M13.0 Polyarthritis, unspecified	0.694	0.305
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.694	0.306
S89 Other and unspecified injuries of lower leg	0.694	0.306
S88 Traumatic amputation of lower leg	0.694	0.306
S87 Crushing injury of lower leg	0.694	0.306
S86 Injury of muscle and tendon at lower leg level	0.694	0.306
S85 Injury of blood vessels at lower leg level	0.694	0.306
S84 Injury of nerves at lower leg level	0.694	0.306
M75.8 Other shoulder lesions	0.694	0.306
M75.9 Shoulder lesion, unspecified	0.694	0.306
O63.9 Long labour, unspecified	0.693	0.307
M40-M43 Deforming dorsopathies	0.692	0.307
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.692	0.308
K04.4 Acute apical periodontitis of pulpal origin	0.692	0.308
K04.3 Abnormal hard tissue formation in pulp	0.692	0.308
K04.2 Pulp degeneration	0.692	0.308
K04.1 Necrosis of pulp	0.692	0.308
K04.0 Pulpitis	0.692	0.308
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.692	0.308
E06 Thyroiditis	0.692	0.308
M14 Arthropathies in other diseases classified elsewhere	0.690	0.310
M12 Other specific arthropathies	0.690	0.310
M09 Juvenile arthritis in diseases classified elsewhere	0.690	0.310
M08 Juvenile arthritis	0.690	0.310
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.690	0.310
G90-G99 Other disorders of the nervous system	0.689	0.311
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.689	0.311
Y35-Y36 Legal intervention and operations of war	0.689	0.311
Y10-Y34 Event of undetermined intent	0.689	0.311
X85-X99 Assault	0.689	0.311
X58-X59 Accidental exposure to other and unspecified factors	0.689	0.311
X30-X39 Exposure to forces of nature	0.689	0.311
X20-X29 Contact with venomous animals and plants	0.689	0.311
X10-X19 Contact with heat and hot substances	0.689	0.311
X00-X09 Exposure to smoke, fire and flames	0.689	0.311
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.689	0.311
W75-W84 Other accidental threats to breathing	0.689	0.311
W65-W74 Accidental drowning and submersion	0.689	0.311
V98-V99 Other and unspecified transport accidents	0.689	0.311
V95-V97 Air and space transport accidents	0.689	0.311
V90-V94 Water transport accidents	0.689	0.311
V70-V79 Bus occupant injured in transport accident	0.689	0.311
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.689	0.311
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.689	0.311
V40-V49 Car occupant injured in transport accident	0.689	0.311
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.689	0.311
V01-V09 Pedestrian injured in transport accident	0.689	0.311
K86.3 Pseudocyst of pancreas	0.689	0.311
C91.1 Chronic lymphocytic leukaemia	0.689	0.311
M86-M90 Other osteopathies	0.688	0.312
L50-L54 Urticaria and erythema	0.688	0.312
M07 Psoriatic and enteropathic arthropathies	0.687	0.313
O63.0 Prolonged first stage (of labour)	0.686	0.314
O36.9 Maternal care for foetal problem, unspecified	0.686	0.314
M05.9 Seropositive rheumatoid arthritis, unspecified	0.685	0.314
M20-M25 Other joint disorders	0.686	0.314
O64 Obstructed labour due to malposition and malpresentation of foetus	0.685	0.315
V10-V19 Pedal cyclist injured in transport accident	0.685	0.315
S12 Fracture of neck	0.683	0.317
S90-S99 Injuries to the ankle and foot	0.682	0.318
X40-X49 Accidental poisoning by and exposure to noxious substances	0.682	0.318
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.681	0.319
M77.0 Medial epicondylitis	0.681	0.319
Z42.1 Follow-up care involving plastic surgery of breast	0.679	0.321
E80 Disorders of porphyrin and bilirubin metabolism	0.678	0.322
S70 Superficial injury of hip and thigh	0.677	0.323
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.677	0.323
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.676	0.323
G00-G09 Inflammatory diseases of the central nervous system	0.676	0.323
O74 Complications of anaesthesia during labour and delivery	0.676	0.324
O71 Other obstetric trauma	0.676	0.324
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.676	0.324
O65 Obstructed labour due to maternal pelvic abnormality	0.676	0.324
O61 Failed induction of labour	0.676	0.324
O60 Preterm delivery	0.676	0.324
Y40 Systemic antibiotics	0.676	0.324
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.675	0.324
C95 Leukaemia of unspecified cell type	0.675	0.324
C94 Other leukaemias of specified cell type	0.675	0.324
C93 Monocytic leukaemia	0.675	0.324
C92 Myeloid leukaemia	0.675	0.324
C86 Other specified types of T/NK-cell lymphoma	0.675	0.324
C84 Peripheral and cutaneous T-cell lymphomas	0.675	0.324
S50-S59 Injuries to the elbow and forearm	0.675	0.325
M79 Other soft tissue disorders, not elsewhere classified	0.674	0.326
O36.0 Maternal care for rhesus isoimmunisation	0.674	0.326
O42 Premature rupture of membranes	0.673	0.327
E07 Other disorders of thyroid	0.673	0.327
N28.9 Disorder of kidney and ureter, unspecified	0.673	0.327
E83.3 Disorders of phosphorus metabolism	0.672	0.327
M80 Osteoporosis with pathological fracture	0.672	0.328
Y59 Other and unspecified vaccines and biological substances	0.672	0.328
Y58 Bacterial vaccines	0.672	0.328
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.672	0.328
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.672	0.328
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.672	0.328
Y53 Agents primarily affecting the gastro-intestinal system	0.672	0.328
Y50 Central nervous system stimulants, not elsewhere classified	0.672	0.328
Y49 Psychotropic drugs, not elsewhere classified	0.672	0.328
Y48 Anaesthetics and therapeutic gases	0.672	0.328
Y47 Sedatives, hypnotics and antianxiety drugs	0.672	0.328
Y46 Antiepileptics and anti-Parkinsonism drugs	0.672	0.328
Y41 Other systemic anti-infectives and antiparasitics	0.672	0.328
K83.9 Disease of biliary tract, unspecified	0.672	0.328
K83.5 Biliary cyst	0.672	0.328
K83.4 Spasm of sphincter of Oddi	0.672	0.328
K83.3 Fistula of bile duct	0.672	0.328
K83.2 Perforation of bile duct	0.672	0.328
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.672	0.328
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.671	0.329
M84.0 Malunion of fracture	0.671	0.329
C07 Malignant neoplasm of parotid gland	0.670	0.330
E78.9 Disorder of lipoprotein metabolism, unspecified	0.670	0.330
T79-T79 Certain early complications of trauma	0.670	0.330
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.670	0.330
E00 Congenital iodine-deficiency syndrome	0.670	0.330
E02 Subclinical iodine-deficiency hypothyroidism	0.670	0.330
K81 Cholecystitis	0.669	0.331
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.669	0.331
F10.3 Withdrawal state	0.669	0.331
N99.3 Prolapse of vaginal vault after hysterectomy	0.668	0.332
K11.1 Hypertrophy of salivary gland	0.667	0.332
C67.2 Lateral wall of bladder	0.667	0.333
N99.5 Malfunction of external stoma of urinary tract	0.667	0.333
C81 Hodgkin's disease	0.667	0.333
N80-N98 Noninflammatory disorders of female genital tract	0.667	0.333
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.667	0.333
T90 Sequelae of injuries of head	0.666	0.334
L10-L14 Bullous disorders	0.666	0.334
K02.5 Caries with pulp exposure	0.666	0.334
K02.4 Odontoclasia	0.666	0.334
K02.3 Arrested dental caries	0.666	0.334
K02.2 Caries of cementum	0.666	0.334
K02.1 Caries of dentin	0.666	0.334
K02.0 Caries limited to enamel	0.666	0.334
M77.4 Metatarsalgia	0.666	0.334
Z93.9 Artificial opening status, unspecified	0.665	0.334
Z93.8 Other artificial opening status	0.665	0.334
Z93.5 Cystostomy status	0.665	0.334
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.665	0.335
O32.0 Maternal care for unstable lie	0.664	0.336
M11 Other crystal arthropathies	0.663	0.337
S82.80 Fractures of other parts of lower leg (closed)	0.663	0.337
W00-W19 Falls	0.663	0.337
C68 Malignant neoplasm of other and unspecified urinary organs	0.662	0.337
C66 Malignant neoplasm of ureter	0.662	0.337
C65 Malignant neoplasm of renal pelvis	0.662	0.337
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.663	0.337
Q60-Q64 Congenital malformations of the urinary system	0.661	0.339
C09 Malignant neoplasm of tonsil	0.661	0.339
K51 Ulcerative colitis	0.660	0.340
Y43.3 Other antineoplastic drugs	0.660	0.340
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.660	0.340
K65 Peritonitis	0.659	0.341
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.659	0.341
Chapter VIII Diseases of the ear and mastoid process	0.659	0.341
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.659	0.341
E23 Hypofunction and other disorders of pituitary gland	0.659	0.341
K09.2 Other cysts of jaw	0.658	0.342
S71 Open wound of hip and thigh	0.657	0.342
O62.2 Other uterine inertia	0.656	0.344
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.655	0.344
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.655	0.345
Z92.9 Personal history of medical treatment, unspecified	0.655	0.345
Z92.5 Personal history of rehabilitation measures	0.655	0.345
Z44 Fitting and adjustment of external prosthetic device	0.654	0.345
S61 Open wound of wrist and hand	0.654	0.345
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.654	0.346
C67.6 Ureteric orifice	0.654	0.346
N26 Unspecified contracted kidney	0.653	0.347
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.653	0.347
N27 Small kidney of unknown cause	0.653	0.347
N25 Disorders resulting from impaired renal tubular function	0.653	0.347
N17.9 Acute renal failure, unspecified	0.652	0.348
D45 Polycythaemia vera	0.652	0.348
O75.7 Vaginal delivery following previous Caesarean section	0.652	0.348
T14 Injury of unspecified body region	0.650	0.350
O32.1 Maternal care for breech presentation	0.650	0.350
K12 Stomatitis and related lesions	0.649	0.351
S82.5 Fracture of medial malleolus	0.649	0.351
N80 Endometriosis	0.649	0.351
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.648	0.352
M83 Adult osteomalacia	0.648	0.352
M82 Osteoporosis in diseases classified elsewhere	0.648	0.352
S42.0 Fracture of clavicle	0.648	0.352
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.648	0.352
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.647	0.352
F70-F79 Mental retardation	0.647	0.352
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.647	0.353
K11.8 Other diseases of salivary glands	0.647	0.353
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.646	0.354
S80.7 Multiple superficial injuries of lower leg	0.646	0.354
S80.1 Contusion of other and unspecified parts of lower leg	0.646	0.354
N99.8 Other postprocedural disorders of genito-urinary system	0.645	0.354
Q50-Q56 Congenital malformations of genital organs	0.645	0.355

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations