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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17431838
log Bayes Factor = 16.1776
Chromosome 7   position 78,079,123  (GRCh37) Explore rs17431838 on Ensembl!
Variant rs17431838 is part of Cluster X0073

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.999 0.001 0.000
Chapter II Neoplasms
0.998 0.002 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.998 0.002 0.000
Z86 Personal history of certain other diseases
0.995 0.005 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.993 0.007 0.000
E10-E14 Diabetes mellitus
0.991 0.009 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.988 0.012 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.988 0.012 0.000
Z92 Personal history of medical treatment
0.986 0.014 0.000
Chapter XIV Diseases of the genitourinary system
0.979 0.021 0.000
Z86.7 Personal history of diseases of the circulatory system
0.972 0.028 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.972 0.028 0.000
I50 Heart failure
0.969 0.031 0.000
E10 Insulin-dependent diabetes mellitus
0.968 0.032 0.000
I20-I25 Ischaemic heart diseases
0.964 0.036 0.000
O60-O75 Complications of labour and delivery
0.962 0.038 0.000
Chapter VII Diseases of the eye and adnexa
0.962 0.038 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.959 0.041 0.000
Z92.3 Personal history of irradiation
0.958 0.042 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.956 0.044 0.000
I60-I69 Cerebrovascular diseases
0.950 0.050 0.000
E10.9 Without complications
0.949 0.051 0.000
I44 Atrioventricular and left bundle-branch block
0.948 0.052 0.000
Z95.0 Presence of cardiac pacemaker
0.944 0.056 0.000
I51 Complications and ill-defined descriptions of heart disease
0.943 0.057 0.000
C15-C26 Malignant neoplasms of digestive organs
0.943 0.057 0.000
C51-C58 Malignant neoplasms of female genital organs
0.938 0.062 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.937 0.063 0.000
Chapter I Certain infectious and parasitic diseases
0.936 0.064 0.000
N17-N19 Renal failure
0.930 0.070 0.000
I50.0 Congestive heart failure
0.930 0.070 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.930 0.070 0.000
E11 Non-insulin-dependent diabetes mellitus
0.923 0.077 0.000
H53-H54 Visual disturbances and blindness
0.919 0.081 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.914 0.086 0.000
Z86.0 Personal history of other neoplasms
0.912 0.088 0.000
Chapter X Diseases of the respiratory system
0.912 0.088 0.000
I73 Other peripheral vascular diseases
0.911 0.089 0.000
N00-N08 Glomerular diseases
0.909 0.091 0.000
S80-S89 Injuries to the knee and lower leg
0.902 0.098 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.900 0.100 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.900 0.100 0.000
E14 Unspecified diabetes mellitus
0.890 0.110 0.000
Chapter VI Diseases of the nervous system
0.890 0.110 0.000
I44.1 Atrioventricular block, second degree
0.889 0.111 0.000
I24 Other acute ischaemic heart diseases
0.889 0.111 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.884 0.116 0.000
I21 Acute myocardial infarction
0.881 0.119 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.880 0.120 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.880 0.120 0.000
I95 Hypotension
0.880 0.120 0.000
C18 Malignant neoplasm of colon
0.879 0.121 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.876 0.124 0.000
N10-N16 Renal tubulo-interstitial diseases
0.876 0.124 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.876 0.124 0.000
S00-S09 Injuries to the head
0.875 0.125 0.000
O63 Long labour
0.872 0.128 0.000
N30-N39 Other diseases of urinary system
0.872 0.128 0.000
O48 Prolonged pregnancy
0.859 0.141 0.000
I44.0 Atrioventricular block, first degree
0.858 0.142 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.856 0.144 0.000
I51.7 Cardiomegaly
0.854 0.146 0.000
C56 Malignant neoplasm of ovary
0.853 0.147 0.000
S40-S49 Injuries to the shoulder and upper arm
0.852 0.148 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.851 0.149 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.850 0.150 0.000
O42 Premature rupture of membranes
0.849 0.151 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.847 0.153 0.000
H54 Blindness and low vision
0.845 0.155 0.000
I21.9 Acute myocardial infarction, unspecified
0.842 0.158 0.000
I74 Arterial embolism and thrombosis
0.841 0.159 0.000
Z89 Acquired absence of limb
0.840 0.160 0.000
I49 Other cardiac arrhythmias
0.839 0.161 0.000
O47 False labour
0.838 0.162 0.000
B35-B49 Mycoses
0.838 0.162 0.000
N35 Urethral stricture
0.837 0.163 0.000
I38 Endocarditis, valve unspecified
0.837 0.163 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.836 0.164 0.000
I73.0 Raynaud's syndrome
0.836 0.164 0.000
H55-H59 Other disorders of eye and adnexa
0.835 0.165 0.000
O36 Maternal care for other known or suspected foetal problems
0.829 0.171 0.000
H40-H42 Glaucoma
0.828 0.172 0.000
I67 Other cerebrovascular diseases
0.826 0.174 0.000
I51.8 Other ill-defined heart diseases
0.826 0.174 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.823 0.177 0.000
I71 Aortic aneurysm and dissection
0.823 0.177 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.823 0.177 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.822 0.178 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.820 0.180 0.000
N17 Acute renal failure
0.819 0.181 0.000
E14.9 Without complications
0.818 0.182 0.000
N99-N99 Other disorders of the genitourinary system
0.818 0.182 0.000
H53 Visual disturbances
0.814 0.186 0.000
O80-O84 Delivery
0.813 0.187 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.813 0.187 0.000
N35.9 Urethral stricture, unspecified
0.813 0.187 0.000
Z95.1 Presence of aortocoronary bypass graft
0.812 0.188 0.000
J90-J94 Other diseases of pleura
0.811 0.189 0.000
I05-I09 Chronic rheumatic heart diseases
0.811 0.189 0.000
I30 Acute pericarditis
0.808 0.192 0.000
N18 Chronic renal failure
0.808 0.192 0.000
O63.0 Prolonged first stage (of labour)
0.806 0.194 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.806 0.194 0.000
I95.1 Orthostatic hypotension
0.805 0.195 0.000
A00-A09 Intestinal infectious diseases
0.804 0.196 0.000
N13 Obstructive and reflux uropathy
0.804 0.196 0.000
I77 Other disorders of arteries and arterioles
0.801 0.199 0.000
I63 Cerebral infarction
0.797 0.203 0.000
I50.1 Left ventricular failure
0.796 0.204 0.000
C34 Malignant neoplasm of bronchus and lung
0.796 0.204 0.000
I42 Cardiomyopathy
0.795 0.205 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.794 0.206 0.000
Q80-Q89 Other congenital malformations
0.793 0.207 0.000
E11.4 With neurological complications
0.792 0.208 0.000
Z88.5 Personal history of allergy to narcotic agent
0.791 0.209 0.000
S82 Fracture of lower leg, including ankle
0.789 0.210 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.788 0.212 0.000
Z03.8 Observation for other suspected diseases and conditions
0.788 0.212 0.000
H43-H45 Disorders of vitreous body and globe
0.788 0.212 0.000
O72 Postpartum haemorrhage
0.786 0.214 0.000
C20 Malignant neoplasm of rectum
0.784 0.216 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.783 0.217 0.000
C78.7 Secondary malignant neoplasm of liver
0.781 0.219 0.000
I25 Chronic ischaemic heart disease
0.780 0.220 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.779 0.221 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.778 0.222 0.000
N30 Cystitis
0.778 0.222 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.776 0.224 0.000
O41 Other disorders of amniotic fluid and membranes
0.776 0.224 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.774 0.226 0.000
B95-B98 Bacterial, viral and other infectious agents
0.773 0.227 0.000
E20-E35 Disorders of other endocrine glands
0.772 0.227 0.000
I70 Atherosclerosis
0.772 0.228 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.769 0.231 0.000
I72 Other aneurysm
0.768 0.232 0.000
I31 Other diseases of pericardium
0.768 0.232 0.000
C80 Malignant neoplasm without specification of site
0.766 0.234 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.765 0.235 0.000
E11.3 With ophthalmic complications
0.764 0.236 0.000
N03 Chronic nephritic syndrome
0.763 0.237 0.000
T66-T78 Other and unspecified effects of external causes
0.762 0.238 0.000
S89 Other and unspecified injuries of lower leg
0.762 0.238 0.000
O66 Other obstructed labour
0.761 0.239 0.000
C54 Malignant neoplasm of corpus uteri
0.760 0.240 0.000
I24.8 Other forms of acute ischaemic heart disease
0.760 0.240 0.000
I25.2 Old myocardial infarction
0.759 0.241 0.000
J40-J47 Chronic lower respiratory diseases
0.758 0.242 0.000
E10.3 With ophthalmic complications
0.757 0.243 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.756 0.244 0.000
C18.9 Colon, unspecified
0.754 0.246 0.000
Z98 Other postsurgical states
0.754 0.246 0.000
N04 Nephrotic syndrome
0.753 0.247 0.000
N19 Unspecified renal failure
0.753 0.247 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.753 0.247 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.752 0.248 0.000
O30 Multiple gestation
0.751 0.249 0.000
I33 Acute and subacute endocarditis
0.751 0.249 0.000
Z85 Personal history of malignant neoplasm
0.751 0.249 0.000
I78 Diseases of capillaries
0.749 0.250 0.000
J60-J70 Lung diseases due to external agents
0.749 0.251 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.748 0.252 0.000
Q60-Q64 Congenital malformations of the urinary system
0.747 0.252 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.747 0.253 0.000
Q21 Congenital malformations of cardiac septa
0.747 0.253 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.743 0.257 0.000
E11.6 With other specified complications
0.743 0.257 0.000
J30-J39 Other diseases of upper respiratory tract
0.742 0.258 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.741 0.259 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.741 0.259 0.000
N05 Unspecified nephritic syndrome
0.741 0.259 0.000
N17.9 Acute renal failure, unspecified
0.740 0.260 0.000
Chapter VIII Diseases of the ear and mastoid process
0.740 0.260 0.000
E40-E46 Malnutrition
0.740 0.260 0.000
S42 Fracture of shoulder and upper arm
0.739 0.261 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.739 0.261 0.000
Chapter XXII Codes for special purposes
0.738 0.262 0.000
I47 Paroxysmal tachycardia
0.737 0.263 0.000
C53 Malignant neoplasm of cervix uteri
0.735 0.265 0.000
E11.2 With renal complications
0.734 0.266 0.000
I50.9 Heart failure, unspecified
0.733 0.267 0.000
H40 Glaucoma
0.733 0.267 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.733 0.267 0.000
I95.9 Hypotension, unspecified
0.732 0.268 0.000
B35 Dermatophytosis
0.731 0.269 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.730 0.270 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.729 0.270 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.729 0.271 0.000
C50-C50 Malignant neoplasm of breast
0.729 0.271 0.000
C25 Malignant neoplasm of pancreas
0.726 0.274 0.000
H54.7 Unspecified visual loss
0.725 0.275 0.000
Z97 Presence of other devices
0.725 0.275 0.000
I73.9 Peripheral vascular disease, unspecified
0.724 0.276 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.723 0.277 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.722 0.278 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.722 0.278 0.000
N25-N29 Other disorders of kidney and ureter
0.721 0.279 0.000
N13.3 Other and unspecified hydronephrosis
0.721 0.279 0.000
I67.9 Cerebrovascular disease, unspecified
0.720 0.280 0.000
H54.0 Blindness, both eyes
0.720 0.280 0.000
Z93 Artificial opening status
0.718 0.282 0.000
B15-B19 Viral hepatitis
0.718 0.282 0.000
G90-G99 Other disorders of the nervous system
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.717 0.283 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
Z84 Family history of other conditions
0.716 0.284 0.000
Z81 Family history of mental and behavioural disorders
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
O85-O92 Complications predominantly related to the puerperium
0.716 0.284 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.715 0.285 0.000
M15-M19 Arthrosis
0.715 0.285 0.000
C18.4 Transverse colon
0.715 0.285 0.000
S06 Intracranial injury
0.715 0.285 0.000
I65.2 Occlusion and stenosis of carotid artery
0.714 0.286 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.714 0.286 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.713 0.286 0.000
Q00-Q07 Congenital malformations of the nervous system
0.712 0.288 0.000
O70 Perineal laceration during delivery
0.711 0.289 0.000
O73 Retained placenta and membranes, without haemorrhage
0.711 0.289 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.711 0.289 0.000
G20-G26 Extrapyramidal and movement disorders
0.710 0.289 0.000
E13 Other specified diabetes mellitus
0.710 0.290 0.000
E12 Malnutrition-related diabetes mellitus
0.710 0.290 0.000
H55 Nystagmus and other irregular eye movements
0.710 0.290 0.000
C18.7 Sigmoid colon
0.710 0.290 0.000
Z89.4 Acquired absence of foot and ankle
0.710 0.290 0.000
E70-E90 Metabolic disorders
0.709 0.291 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.709 0.291 0.000
O45 Premature separation of placenta [abruptio placentae]
0.708 0.292 0.000
O44 Placenta praevia
0.708 0.292 0.000
O43 Placental disorders
0.708 0.292 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.708 0.292 0.000
O33 Maternal care for known or suspected disproportion
0.708 0.292 0.000
O31 Complications specific to multiple gestation
0.708 0.292 0.000
O40 Polyhydramnios
0.708 0.292 0.000
S50-S59 Injuries to the elbow and forearm
0.708 0.292 0.000
Z92.9 Personal history of medical treatment, unspecified
0.707 0.293 0.000
Z92.8 Personal history of other medical treatment
0.707 0.293 0.000
Z92.5 Personal history of rehabilitation measures
0.707 0.293 0.000
Z92.0 Personal history of contraception
0.707 0.293 0.000
Z95.4 Presence of other heart-valve replacement
0.706 0.294 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.704 0.296 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.704 0.296 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.703 0.297 0.000
S00 Superficial injury of head
0.703 0.297 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.703 0.297 0.000
Z88.2 Personal history of allergy to sulphonamides
0.702 0.298 0.000
S20-S29 Injuries to the thorax
0.702 0.298 0.000
C78.2 Secondary malignant neoplasm of pleura
0.702 0.298 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.701 0.299 0.000
C34.1 Upper lobe, bronchus or lung
0.699 0.301 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.698 0.302 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.697 0.303 0.000
T79-T79 Certain early complications of trauma
0.697 0.303 0.000
T33-T35 Frostbite
0.697 0.303 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.697 0.303 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.697 0.303 0.000
T00-T07 Injuries involving multiple body regions
0.697 0.303 0.000
S10-S19 Injuries to the neck
0.697 0.303 0.000
D00-D09 In situ neoplasms
0.696 0.304 0.000
D10-D36 Benign neoplasms
0.696 0.304 0.000
O62 Abnormalities of forces of labour
0.695 0.305 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.695 0.305 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.695 0.305 0.000
H30-H36 Disorders of choroid and retina
0.694 0.306 0.000
E10.8 With unspecified complications
0.694 0.306 0.000
E10.7 With multiple complications
0.694 0.306 0.000
E10.6 With other specified complications
0.694 0.306 0.000
E10.5 With peripheral circulatory complications
0.694 0.306 0.000
E10.4 With neurological complications
0.694 0.306 0.000
E10.2 With renal complications
0.694 0.306 0.000
E10.0 With coma
0.694 0.306 0.000
S81 Open wound of lower leg
0.694 0.306 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.694 0.306 0.000
H53.8 Other visual disturbances
0.693 0.307 0.000
A80-A89 Viral infections of the central nervous system
0.692 0.308 0.000
I23 Certain current complications following acute myocardial infarction
0.691 0.308 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.691 0.309 0.000
O74 Complications of anaesthesia during labour and delivery
0.689 0.310 0.000
O71 Other obstetric trauma
0.689 0.310 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.689 0.310 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.689 0.310 0.000
O61 Failed induction of labour
0.689 0.310 0.000
O60 Preterm delivery
0.689 0.310 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.689 0.311 0.000
Z36 Antenatal screening
0.689 0.311 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.688 0.312 0.000
Z95.3 Presence of xenogenic heart valve
0.688 0.312 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.688 0.312 0.000
E11.5 With peripheral circulatory complications
0.687 0.313 0.000
C64-C68 Malignant neoplasms of urinary tract
0.687 0.313 0.000
O36.8 Maternal care for other specified foetal problems
0.686 0.314 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.685 0.314 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.685 0.314 0.000
Q50-Q56 Congenital malformations of genital organs
0.685 0.314 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.685 0.314 0.000
Q35-Q37 Cleft lip and cleft palate
0.685 0.314 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.685 0.314 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.685 0.315 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.685 0.315 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.684 0.316 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.684 0.316 0.000
I46 Cardiac arrest
0.683 0.317 0.000
J95-J99 Other diseases of the respiratory system
0.682 0.318 0.000
B37 Candidiasis
0.682 0.318 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.681 0.319 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.681 0.319 0.000
J93 Pneumothorax
0.681 0.319 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.680 0.320 0.000
I67.2 Cerebral atherosclerosis
0.680 0.320 0.000
O80 Single spontaneous delivery
0.680 0.320 0.000
I44.6 Other and unspecified fascicular block
0.680 0.320 0.000
I44.5 Left posterior fascicular block
0.680 0.320 0.000
I44.4 Left anterior fascicular block
0.680 0.320 0.000
I44.3 Other and unspecified atrioventricular block
0.680 0.320 0.000
A08 Viral and other specified intestinal infections
0.679 0.321 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.679 0.321 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.679 0.321 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.679 0.321 0.000
H10-H13 Disorders of conjunctiva
0.679 0.321 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.678 0.321 0.000
M17 Gonarthrosis [arthrosis of knee]
0.678 0.322 0.000
N11 Chronic tubulo-interstitial nephritis
0.677 0.322 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.677 0.323 0.000
Z29 Need for other prophylactic measures
0.677 0.323 0.000
I51.6 Cardiovascular disease, unspecified
0.676 0.324 0.000
I51.5 Myocardial degeneration
0.676 0.324 0.000
I51.4 Myocarditis, unspecified
0.676 0.324 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.676 0.324 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.676 0.324 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.676 0.324 0.000
I51.0 Cardiac septal defect, acquired
0.676 0.324 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.676 0.324 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.676 0.324 0.000
C21 Malignant neoplasm of anus and anal canal
0.676 0.324 0.000
C17 Malignant neoplasm of small intestine
0.676 0.324 0.000
C23 Malignant neoplasm of gallbladder
0.676 0.324 0.000
H43 Disorders of vitreous body
0.676 0.324 0.000
S01 Open wound of head
0.676 0.324 0.000
I44.7 Left bundle-branch block, unspecified
0.675 0.325 0.000
I49.4 Other and unspecified premature depolarisation
0.674 0.326 0.000
N18.9 Chronic renal failure, unspecified
0.674 0.326 0.000
S09 Other and unspecified injuries of head
0.674 0.326 0.000
Q21.1 Atrial septal defect
0.673 0.326 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.673 0.327 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.672 0.328 0.000
C51 Malignant neoplasm of vulva
0.672 0.328 0.000
C58 Malignant neoplasm of placenta
0.672 0.328 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.672 0.328 0.000
C52 Malignant neoplasm of vagina
0.672 0.328 0.000
G62 Other polyneuropathies
0.672 0.328 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.672 0.328 0.000
I99 Other and unspecified disorders of circulatory system
0.672 0.328 0.000
S82.4 Fracture of fibula alone
0.672 0.328 0.000
I51.9 Heart disease, unspecified
0.672 0.328 0.000
Q27 Other congenital malformations of peripheral vascular system
0.672 0.328 0.000
B99-B99 Other infectious diseases
0.671 0.329 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.671 0.329 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.671 0.329 0.000
B65-B83 Helminthiases
0.671 0.329 0.000
B50-B64 Protozoal diseases
0.671 0.329 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.671 0.329 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.671 0.329 0.000
A75-A79 Rickettsioses
0.671 0.329 0.000
A70-A74 Other diseases caused by chlamydiae
0.671 0.329 0.000
A65-A69 Other spirochaetal diseases
0.671 0.329 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.671 0.329 0.000
A20-A28 Certain zoonotic bacterial diseases
0.671 0.329 0.000
A15-A19 Tuberculosis
0.671 0.329 0.000
I07 Rheumatic tricuspid valve diseases
0.670 0.329 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.670 0.330 0.000
I30.9 Acute pericarditis, unspecified
0.670 0.330 0.000
C78.0 Secondary malignant neoplasm of lung
0.669 0.331 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.669 0.331 0.000
I45 Other conduction disorders
0.668 0.332 0.000
M45-M49 Spondylopathies
0.667 0.333 0.000
I60 Subarachnoid haemorrhage
0.667 0.333 0.000
H53.4 Visual field defects
0.667 0.333 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.666 0.333 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.666 0.333 0.000
S80 Superficial injury of lower leg
0.666 0.334 0.000
O32.1 Maternal care for breech presentation
0.665 0.335 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.665 0.335 0.000
I63.9 Cerebral infarction, unspecified
0.664 0.336 0.000
I49.3 Ventricular premature depolarisation
0.664 0.336 0.000
N30.3 Trigonitis
0.664 0.336 0.000
J90 Pleural effusion, not elsewhere classified
0.663 0.337 0.000
I62 Other nontraumatic intracranial haemorrhage
0.663 0.337 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.663 0.337 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.663 0.337 0.000
C34.3 Lower lobe, bronchus or lung
0.662 0.338 0.000
E11.8 With unspecified complications
0.662 0.338 0.000
E11.7 With multiple complications
0.662 0.338 0.000
E11.1 With ketoacidosis
0.662 0.338 0.000
E11.0 With coma
0.662 0.338 0.000
S89.9 Unspecified injury of lower leg
0.662 0.338 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.661 0.339 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.661 0.339 0.000
J43 Emphysema
0.661 0.339 0.000
C18.2 Ascending colon
0.661 0.339 0.000
S90-S99 Injuries to the ankle and foot
0.660 0.340 0.000
N03.9 Unspecified
0.659 0.341 0.000
N18.4 Chronic kidney disease, stage 4
0.659 0.341 0.000
C79 Secondary malignant neoplasm of other sites
0.659 0.341 0.000
I74.5 Embolism and thrombosis of iliac artery
0.658 0.342 0.000
O47.9 False labour, unspecified
0.657 0.343 0.000
E10.1 With ketoacidosis
0.657 0.343 0.000
M86-M90 Other osteopathies
0.657 0.343 0.000
S82.0 Fracture of patella
0.655 0.345 0.000
N30.9 Cystitis, unspecified
0.655 0.345 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.654 0.346 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.654 0.346 0.000
I73.8 Other specified peripheral vascular diseases
0.653 0.346 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.653 0.346 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.653 0.347 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.652 0.348 0.000
N02 Recurrent and persistent haematuria
0.652 0.348 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.652 0.348 0.000
N06 Isolated proteinuria with specified morphological lesion
0.652 0.348 0.000
N01 Rapidly progressive nephritic syndrome
0.652 0.348 0.000
N00 Acute nephritic syndrome
0.652 0.348 0.000
C18.0 Caecum
0.651 0.349 0.000
M80-M85 Disorders of bone density and structure
0.651 0.349 0.000
C15 Malignant neoplasm of oesophagus
0.650 0.350 0.000
H53.2 Diplopia
0.650 0.350 0.000
I95.2 Hypotension due to drugs
0.649 0.351 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.649 0.351 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.648 0.352 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.648 0.352 0.000
S70-S79 Injuries to the hip and thigh
0.648 0.352 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.648 0.352 0.000
H57 Other disorders of eye and adnexa
0.648 0.352 0.000
S88 Traumatic amputation of lower leg
0.646 0.354 0.000
S87 Crushing injury of lower leg
0.646 0.354 0.000
S86 Injury of muscle and tendon at lower leg level
0.646 0.354 0.000
S85 Injury of blood vessels at lower leg level
0.646 0.354 0.000
S84 Injury of nerves at lower leg level
0.646 0.354 0.000
I22 Subsequent myocardial infarction
0.646 0.354 0.000
E50-E64 Other nutritional deficiencies
0.645 0.354 0.000
Z10 Routine general health check-up of defined subpopulation
0.645 0.355 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.645 0.355 0.000
J09-J18 Influenza and pneumonia
0.645 0.355 0.000
I69 Sequelae of cerebrovascular disease
0.645 0.355 0.000
Z03.4 Observation for suspected myocardial infarction
0.645 0.355 0.000
H40.0 Glaucoma suspect
0.645 0.355 0.000
T81 Complications of procedures, not elsewhere classified
0.644 0.356 0.000
M00-M03 Infectious arthropathies
0.644 0.356 0.000
O36.9 Maternal care for foetal problem, unspecified
0.643 0.356 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.642 0.357 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.642 0.357 0.000
H53.1 Subjective visual disturbances
0.642 0.358 0.000
Z00.6 Examination for normal comparison and control in clinical research programme
0.642 0.358 0.000
G61 Inflammatory polyneuropathy
0.642 0.358 0.000
H54.9 Unspecified visual impairment (binocular)
0.642 0.358 0.000
N04.9 Unspecified
0.642 0.358 0.000
Q89 Other congenital malformations, not elsewhere classified
0.641 0.359 0.000
G70-G73 Diseases of myoneural junction and muscle
0.640 0.360 0.000
S02 Fracture of skull and facial bones
0.639 0.361 0.000
Chapter XI Diseases of the digestive system
0.639 0.361 0.000
E14.8 With unspecified complications
0.638 0.362 0.000
E14.7 With multiple complications
0.638 0.362 0.000
E14.6 With other specified complications
0.638 0.362 0.000
E14.5 With peripheral circulatory complications
0.638 0.362 0.000
E14.4 With neurological complications
0.638 0.362 0.000
E14.3 With ophthalmic complications
0.638 0.362 0.000
E14.2 Withrenal complications
0.638 0.362 0.000
E14.1 With ketoacidosis
0.638 0.362 0.000
E14.0 With coma
0.638 0.362 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.638 0.362 0.000
I77.1 Stricture of artery
0.638 0.362 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.638 0.362 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.638 0.362 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.638 0.362 0.000
I24.1 Dressler's syndrome
0.637 0.363 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.637 0.363 0.000
I31.9 Disease of pericardium, unspecified
0.637 0.363 0.000
Chapter XX External causes of morbidity and mortality
0.637 0.363 0.000
A04 Other bacterial intestinal infections
0.637 0.363 0.000
O42.9 Premature rupture of membranes, unspecified
0.636 0.364 0.000
E00-E07 Disorders of thyroid gland
0.635 0.365 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.634 0.366 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.634 0.366 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.634 0.366 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.634 0.366 0.000
E83 Disorders of mineral metabolism
0.633 0.367 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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