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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17450512
log Bayes Factor = 11.1355
Chromosome 5   position 118,676,043  (GRCh37) Explore rs17450512 on Ensembl!
Variant rs17450512 is part of Cluster X0171

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
J43 Emphysema
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
J44 Other chronic obstructive pulmonary disease
0.999 0.001 0.000
J43.9 Emphysema, unspecified
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.993 0.007 0.000
Chapter IX Diseases of the circulatory system
0.993 0.007 0.000
E70-E90 Metabolic disorders
0.991 0.009 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.987 0.013 0.000
M05-M14 Inflammatory polyarthropathies
0.986 0.014 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.984 0.016 0.000
Chapter V Mental and behavioural disorders
0.984 0.016 0.000
M80-M85 Disorders of bone density and structure
0.981 0.019 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.979 0.021 0.000
M81 Osteoporosis without pathological fracture
0.972 0.028 0.000
M06 Other rheumatoid arthritis
0.972 0.028 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.971 0.029 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.963 0.037 0.000
M06.9 Rheumatoid arthritis, unspecified
0.963 0.037 0.000
M81.9 Osteoporosis, unspecified
0.961 0.039 0.000
Chapter VI Diseases of the nervous system
0.958 0.042 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.956 0.044 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.953 0.047 0.000
E86 Volume depletion
0.951 0.049 0.000
E87.2 Acidosis
0.944 0.056 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.944 0.056 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.943 0.057 0.000
L20-L30 Dermatitis and eczema
0.938 0.062 0.000
Chapter VII Diseases of the eye and adnexa
0.934 0.066 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.933 0.067 0.000
Q60-Q64 Congenital malformations of the urinary system
0.933 0.067 0.000
L30 Other dermatitis
0.933 0.067 0.000
L30.9 Dermatitis, unspecified
0.929 0.071 0.000
J30-J39 Other diseases of upper respiratory tract
0.928 0.072 0.000
E10-E14 Diabetes mellitus
0.924 0.076 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.920 0.080 0.000
I80 Phlebitis and thrombophlebitis
0.915 0.085 0.000
E20-E35 Disorders of other endocrine glands
0.915 0.085 0.000
Chapter I Certain infectious and parasitic diseases
0.914 0.086 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.913 0.087 0.000
I84 Haemorrhoids
0.913 0.087 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.911 0.089 0.000
I84.8 Unspecified haemorrhoids with other complications
0.910 0.090 0.000
E11 Non-insulin-dependent diabetes mellitus
0.909 0.091 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.905 0.095 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.902 0.098 0.000
T93 Sequelae of injuries of lower limb
0.900 0.100 0.000
S10-S19 Injuries to the neck
0.899 0.101 0.000
J33 Nasal polyp
0.897 0.103 0.000
S50-S59 Injuries to the elbow and forearm
0.896 0.104 0.000
J47 Bronchiectasis
0.892 0.108 0.000
Q61 Cystic kidney disease
0.890 0.110 0.000
F10.3 Withdrawal state
0.890 0.110 0.000
I05-I09 Chronic rheumatic heart diseases
0.888 0.112 0.000
E50-E64 Other nutritional deficiencies
0.886 0.114 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.885 0.115 0.000
H30-H36 Disorders of choroid and retina
0.884 0.116 0.000
G30-G32 Other degenerative diseases of the nervous system
0.875 0.125 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.873 0.127 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.872 0.128 0.000
E11.3 With ophthalmic complications
0.869 0.131 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.868 0.132 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.864 0.136 0.000
M10 Gout
0.863 0.137 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.862 0.138 0.000
Q80-Q89 Other congenital malformations
0.857 0.143 0.000
S90-S99 Injuries to the ankle and foot
0.853 0.147 0.000
J32 Chronic sinusitis
0.850 0.150 0.000
I30-I52 Other forms of heart disease
0.849 0.151 0.000
J33.9 Nasal polyp, unspecified
0.848 0.152 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.848 0.152 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.847 0.153 0.000
H34 Retinal vascular occlusions
0.847 0.153 0.000
B95-B98 Bacterial, viral and other infectious agents
0.847 0.153 0.000
T91 Sequelae of injuries of neck and trunk
0.844 0.156 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.843 0.157 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.842 0.158 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.840 0.160 0.000
Q61.0 Congenital single renal cyst
0.840 0.160 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.837 0.163 0.000
E88 Other metabolic disorders
0.836 0.164 0.000
T66-T78 Other and unspecified effects of external causes
0.833 0.167 0.000
I74 Arterial embolism and thrombosis
0.832 0.168 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.832 0.168 0.000
I84.4 External haemorrhoids with other complications
0.831 0.169 0.000
J32.9 Chronic sinusitis, unspecified
0.829 0.171 0.000
J43.2 Centrilobular emphysema
0.829 0.171 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.829 0.171 0.000
S20-S29 Injuries to the thorax
0.826 0.174 0.000
E11.4 With neurological complications
0.825 0.175 0.000
E87.6 Hypokalaemia
0.818 0.182 0.000
F10.2 Dependence syndrome
0.816 0.184 0.000
I38 Endocarditis, valve unspecified
0.815 0.185 0.000
T93.1 Sequelae of fracture of femur
0.814 0.186 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.813 0.187 0.000
Chapter XX External causes of morbidity and mortality
0.811 0.189 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.811 0.189 0.000
L29 Pruritus
0.809 0.191 0.000
I08 Multiple valve diseases
0.806 0.194 0.000
E11.5 With peripheral circulatory complications
0.805 0.195 0.000
J31.0 Chronic rhinitis
0.804 0.196 0.000
S19 Other and unspecified injuries of neck
0.803 0.197 0.000
B99-B99 Other infectious diseases
0.803 0.197 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.803 0.197 0.000
H43-H45 Disorders of vitreous body and globe
0.803 0.197 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.802 0.198 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.801 0.199 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.801 0.199 0.000
J42 Unspecified chronic bronchitis
0.799 0.201 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.799 0.201 0.000
M00-M03 Infectious arthropathies
0.799 0.201 0.000
M81.4 Drug-induced osteoporosis
0.798 0.202 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.797 0.203 0.000
I45 Other conduction disorders
0.797 0.203 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.795 0.205 0.000
S32 Fracture of lumbar spine and pelvis
0.795 0.205 0.000
E24 Cushing's syndrome
0.795 0.205 0.000
G90-G99 Other disorders of the nervous system
0.789 0.211 0.000
H36 Retinal disorders in diseases classified elsewhere
0.789 0.211 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.786 0.213 0.000
M11 Other crystal arthropathies
0.786 0.214 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.786 0.214 0.000
M07 Psoriatic and enteropathic arthropathies
0.785 0.215 0.000
S40-S49 Injuries to the shoulder and upper arm
0.783 0.217 0.000
E22 Hyperfunction of pituitary gland
0.782 0.217 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.782 0.218 0.000
I45.1 Other and unspecified right bundle-branch block
0.780 0.220 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.777 0.223 0.000
M10.9 Gout, unspecified
0.775 0.225 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.774 0.226 0.000
I35 Nonrheumatic aortic valve disorders
0.774 0.226 0.000
I77 Other disorders of arteries and arterioles
0.773 0.227 0.000
F17.2 Dependence syndrome
0.769 0.231 0.000
I84.0 Internal thrombosed haemorrhoids
0.768 0.232 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.767 0.233 0.000
H55-H59 Other disorders of eye and adnexa
0.764 0.236 0.000
E40-E46 Malnutrition
0.764 0.236 0.000
M60-M63 Disorders of muscles
0.763 0.237 0.000
T95 Sequelae of burns, corrosions and frostbite
0.760 0.240 0.000
E87.3 Alkalosis
0.760 0.240 0.000
H34.8 Other retinal vascular occlusions
0.758 0.242 0.000
B15-B19 Viral hepatitis
0.757 0.243 0.000
J36 Peritonsillar abscess
0.757 0.243 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.756 0.244 0.000
M91-M94 Chondropathies
0.755 0.245 0.000
E55 Vitamin D deficiency
0.755 0.245 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.754 0.246 0.000
I85 Oesophageal varices
0.754 0.246 0.000
Q61.3 Polycystic kidney, unspecified
0.754 0.246 0.000
M85 Other disorders of bone density and structure
0.754 0.246 0.000
T93.0 Sequelae of open wound of lower limb
0.752 0.248 0.000
H34.2 Other retinal artery occlusions
0.752 0.248 0.000
F11 Mental and behavioural disorders due to use of opioids
0.752 0.248 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.751 0.249 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.751 0.249 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.751 0.249 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.750 0.250 0.000
G20-G26 Extrapyramidal and movement disorders
0.748 0.252 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.748 0.252 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.746 0.254 0.000
E26 Hyperaldosteronism
0.745 0.255 0.000
T98 Sequelae of other and unspecified effects of external causes
0.743 0.257 0.000
J33.0 Polyp of nasal cavity
0.743 0.257 0.000
I73 Other peripheral vascular diseases
0.742 0.258 0.000
G60 Hereditary and idiopathic neuropathy
0.742 0.258 0.000
I87 Other disorders of veins
0.741 0.259 0.000
I60-I69 Cerebrovascular diseases
0.740 0.260 0.000
E73 Lactose intolerance
0.740 0.260 0.000
L29.9 Pruritus, unspecified
0.740 0.260 0.000
I35.1 Aortic (valve) insufficiency
0.738 0.262 0.000
M80 Osteoporosis with pathological fracture
0.736 0.264 0.000
S19.9 Unspecified injury of neck
0.735 0.265 0.000
S92 Fracture of foot, except ankle
0.735 0.265 0.000
E53 Deficiency of other B group vitamins
0.735 0.265 0.000
T23 Burn and corrosion of wrist and hand
0.734 0.266 0.000
I05 Rheumatic mitral valve diseases
0.734 0.266 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.733 0.267 0.000
G70-G73 Diseases of myoneural junction and muscle
0.732 0.268 0.000
S51 Open wound of forearm
0.732 0.268 0.000
M81.2 Osteoporosis of disuse
0.731 0.269 0.000
F10.5 Psychotic disorder
0.731 0.269 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.730 0.270 0.000
M65-M68 Disorders of synovium and tendon
0.728 0.272 0.000
S31 Open wound of abdomen, lower back and pelvis
0.727 0.273 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.726 0.274 0.000
E20 Hypoparathyroidism
0.726 0.274 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.725 0.275 0.000
I84.1 Internal haemorrhoids with other complications
0.725 0.275 0.000
B99 Other and unspecified infectious diseases
0.724 0.276 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.724 0.276 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.723 0.277 0.000
M86-M90 Other osteopathies
0.723 0.277 0.000
F10.4 Withdrawal state with delirium
0.722 0.278 0.000
H36.0 Diabetic retinopathy
0.721 0.279 0.000
D68 Other coagulation defects
0.720 0.280 0.000
D80-D89 Certain disorders involving the immune mechanism
0.719 0.281 0.000
E11.2 With renal complications
0.718 0.282 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.717 0.283 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
F10.6 Amnesic syndrome
0.717 0.283 0.000
J43.8 Other emphysema
0.716 0.284 0.000
J43.1 Panlobular emphysema
0.716 0.284 0.000
J43.0 MacLeod's syndrome
0.716 0.284 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.716 0.284 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.716 0.284 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.716 0.284 0.000
F43 Reaction to severe stress, and adjustment disorders
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.286 0.000
I00-I02 Acute rheumatic fever
0.712 0.288 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.710 0.290 0.000
E85 Amyloidosis
0.710 0.290 0.000
E84 Cystic fibrosis
0.710 0.290 0.000
E79 Disorders of purine and pyrimidine metabolism
0.710 0.290 0.000
E77 Disorders of glycoprotein metabolism
0.710 0.290 0.000
E76 Disorders of glycosaminoglycan metabolism
0.710 0.290 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.710 0.290 0.000
E72 Other disorders of amino-acid metabolism
0.710 0.290 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.710 0.290 0.000
E70 Disorders of aromatic amino-acid metabolism
0.710 0.290 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.710 0.290 0.000
B65-B83 Helminthiases
0.709 0.290 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.709 0.291 0.000
L89 Decubitus ulcer
0.708 0.292 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.708 0.292 0.000
Q35-Q37 Cleft lip and cleft palate
0.708 0.292 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.708 0.292 0.000
M12 Other specific arthropathies
0.707 0.293 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.707 0.293 0.000
M08 Juvenile arthritis
0.707 0.293 0.000
J33.8 Other polyp of sinus
0.707 0.293 0.000
H53-H54 Visual disturbances and blindness
0.706 0.294 0.000
E87.4 Mixed disorder of acid-base balance
0.705 0.295 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.705 0.295 0.000
F70-F79 Mental retardation
0.705 0.295 0.000
M83 Adult osteomalacia
0.703 0.297 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.702 0.298 0.000
M06.0 Seronegative rheumatoid arthritis
0.702 0.298 0.000
L30.8 Other specified dermatitis
0.702 0.298 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.701 0.299 0.000
D68.2 Hereditary deficiency of other clotting factors
0.701 0.299 0.000
H20 Iridocyclitis
0.700 0.300 0.000
S54 Injury of nerves at forearm level
0.700 0.300 0.000
J00-J06 Acute upper respiratory infections
0.700 0.300 0.000
Q89 Other congenital malformations, not elsewhere classified
0.698 0.302 0.000
X60-X84 Intentional self-harm
0.698 0.302 0.000
I70 Atherosclerosis
0.697 0.303 0.000
M81.8 Other osteoporosis
0.697 0.303 0.000
M81.6 Localised osteoporosis [Lequesne]
0.697 0.303 0.000
M81.5 Idiopathic osteoporosis
0.697 0.303 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.697 0.303 0.000
M81.1 Postoophorectomy osteoporosis
0.697 0.303 0.000
M81.0 Postmenopausal osteoporosis
0.697 0.303 0.000
M06.8 Other specified rheumatoid arthritis
0.697 0.303 0.000
M06.3 Rheumatoid nodule
0.697 0.303 0.000
M06.2 Rheumatoid bursitis
0.697 0.303 0.000
M06.1 Adult-onset Still's disease
0.697 0.303 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.696 0.303 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.696 0.303 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.696 0.303 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.696 0.303 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.696 0.303 0.000
Chapter XXII Codes for special purposes
0.695 0.305 0.000
T93.2 Sequelae of other fractures of lower limb
0.694 0.306 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.693 0.306 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.693 0.307 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.693 0.307 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.693 0.307 0.000
S00-S09 Injuries to the head
0.693 0.307 0.000
T68 Hypothermia
0.692 0.308 0.000
Q00-Q07 Congenital malformations of the nervous system
0.691 0.308 0.000
G12 Spinal muscular atrophy and related syndromes
0.691 0.309 0.000
F60-F69 Disorders of adult personality and behaviour
0.691 0.309 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.691 0.309 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.691 0.309 0.000
B50-B64 Protozoal diseases
0.691 0.309 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.690 0.310 0.000
Q50-Q56 Congenital malformations of genital organs
0.690 0.310 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.689 0.311 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.689 0.311 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.689 0.311 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.689 0.311 0.000
D55-D59 Haemolytic anaemias
0.687 0.313 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.686 0.314 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.686 0.314 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.686 0.314 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.686 0.314 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.686 0.314 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.685 0.315 0.000
E74 Other disorders of carbohydrate metabolism
0.684 0.315 0.000
I72 Other aneurysm
0.684 0.315 0.000
L84 Corns and callosities
0.684 0.316 0.000
I77.6 Arteritis, unspecified
0.684 0.316 0.000
M13 Other arthritis
0.683 0.317 0.000
J46 Status asthmaticus
0.681 0.319 0.000
M81.98 Osteoporosis, unspecified (Other)
0.680 0.320 0.000
G60.8 Other hereditary and idiopathic neuropathies
0.680 0.320 0.000
F29 Unspecified nonorganic psychosis
0.680 0.320 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.679 0.321 0.000
S27 Injury of other and unspecified intrathoracic organs
0.678 0.322 0.000
S40 Superficial injury of shoulder and upper arm
0.677 0.323 0.000
E11.1 With ketoacidosis
0.677 0.323 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.676 0.324 0.000
L10-L14 Bullous disorders
0.676 0.324 0.000
E11.0 With coma
0.676 0.324 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.675 0.325 0.000
E23 Hypofunction and other disorders of pituitary gland
0.675 0.325 0.000
G40-G47 Episodic and paroxysmal disorders
0.674 0.326 0.000
G93 Other disorders of brain
0.674 0.326 0.000
S56 Injury of muscle and tendon at forearm level
0.673 0.327 0.000
J37 Chronic laryngitis and laryngotracheitis
0.673 0.327 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.673 0.327 0.000
L25 Unspecified contact dermatitis
0.672 0.328 0.000
L24 Irritant contact dermatitis
0.672 0.328 0.000
L23 Allergic contact dermatitis
0.672 0.328 0.000
L21 Seborrhoeic dermatitis
0.672 0.328 0.000
L20 Atopic dermatitis
0.672 0.328 0.000
L26 Exfoliative dermatitis
0.672 0.328 0.000
L22 Diaper [napkin] dermatitis
0.672 0.328 0.000
G95 Other diseases of spinal cord
0.671 0.329 0.000
S14 Injury of nerves and spinal cord at neck level
0.671 0.329 0.000
I35.9 Aortic valve disorder, unspecified
0.669 0.331 0.000
F10.8 Other mental and behavioural disorders
0.669 0.331 0.000
F10.7 Residual and late-onset psychotic disorder
0.669 0.331 0.000
Q64 Other congenital malformations of urinary system
0.669 0.331 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.669 0.331 0.000
H34.1 Central retinal artery occlusion
0.669 0.331 0.000
L30.5 Pityriasis alba
0.669 0.331 0.000
L30.4 Erythema intertrigo
0.669 0.331 0.000
L30.3 Infective dermatitis
0.669 0.331 0.000
L30.2 Cutaneous autosensitisation
0.669 0.331 0.000
L30.1 Dyshidrosis [pompholyx]
0.669 0.331 0.000
L30.0 Nummular dermatitis
0.669 0.331 0.000
G31.2 Degeneration of nervous system due to alcohol
0.668 0.332 0.000
T90 Sequelae of injuries of head
0.668 0.332 0.000
J32.8 Other chronic sinusitis
0.668 0.332 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.667 0.333 0.000
S11 Open wound of neck
0.667 0.333 0.000
I77.8 Other specified disorders of arteries and arterioles
0.666 0.334 0.000
H43 Disorders of vitreous body
0.666 0.334 0.000
I08.0 Disorders of both mitral and aortic valves
0.666 0.334 0.000
Q23 Congenital malformations of aortic and mitral valves
0.665 0.335 0.000
S99 Other and unspecified injuries of ankle and foot
0.665 0.335 0.000
S50 Superficial injury of forearm
0.665 0.335 0.000
S10 Superficial injury of neck
0.663 0.337 0.000
E16 Other disorders of pancreatic internal secretion
0.663 0.337 0.000
J31.2 Chronic pharyngitis
0.663 0.337 0.000
E24.9 Cushing's syndrome, unspecified
0.662 0.338 0.000
E12 Malnutrition-related diabetes mellitus
0.662 0.338 0.000
Q39 Congenital malformations of oesophagus
0.662 0.338 0.000
E28 Ovarian dysfunction
0.662 0.338 0.000
T20 Burn and corrosion of head and neck
0.662 0.338 0.000
L88 Pyoderma gangrenosum
0.662 0.338 0.000
Q28 Other congenital malformations of circulatory system
0.661 0.339 0.000
M05 Seropositive rheumatoid arthritis
0.661 0.339 0.000
E55.9 Vitamin D deficiency, unspecified
0.660 0.340 0.000
F80-F89 Disorders of psychological development
0.660 0.340 0.000
M00 Pyogenic arthritis
0.659 0.340 0.000
H55 Nystagmus and other irregular eye movements
0.659 0.341 0.000
I88 Nonspecific lymphadenitis
0.659 0.341 0.000
M82 Osteoporosis in diseases classified elsewhere
0.658 0.342 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.658 0.342 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.658 0.342 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.658 0.342 0.000
M14 Arthropathies in other diseases classified elsewhere
0.657 0.342 0.000
H50 Other strabismus
0.657 0.343 0.000
S32.5 Fracture of pubis
0.656 0.343 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.656 0.344 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.656 0.344 0.000
E32 Diseases of thymus
0.656 0.344 0.000
E31 Polyglandular dysfunction
0.656 0.344 0.000
E30 Disorders of puberty, not elsewhere classified
0.656 0.344 0.000
E25 Adrenogenital disorders
0.656 0.344 0.000
H40-H42 Glaucoma
0.656 0.344 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.655 0.345 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.655 0.345 0.000
A75-A79 Rickettsioses
0.655 0.345 0.000
A70-A74 Other diseases caused by chlamydiae
0.655 0.345 0.000
A65-A69 Other spirochaetal diseases
0.655 0.345 0.000
A20-A28 Certain zoonotic bacterial diseases
0.655 0.345 0.000
A15-A19 Tuberculosis
0.655 0.345 0.000
S36 Injury of intra-abdominal organs
0.655 0.345 0.000
T63 Toxic effect of contact with venomous animals
0.654 0.345 0.000
E29 Testicular dysfunction
0.654 0.346 0.000
Q85 Phakomatoses, not elsewhere classified
0.654 0.346 0.000
F03 Unspecified dementia
0.654 0.346 0.000
T79-T79 Certain early complications of trauma
0.654 0.346 0.000
E11.7 With multiple complications
0.652 0.348 0.000
L27 Dermatitis due to substances taken internally
0.652 0.348 0.000
I86 Varicose veins of other sites
0.651 0.349 0.000
Q63 Other congenital malformations of kidney
0.651 0.349 0.000
Q82 Other congenital malformations of skin
0.651 0.349 0.000
S12 Fracture of neck
0.651 0.349 0.000
E87.5 Hyperkalaemia
0.650 0.350 0.000
M81.49 Drug-induced osteoporosis (Site unspecified)
0.649 0.351 0.000
T23.3 Burn of third degree of wrist and hand
0.649 0.351 0.000
E24.2 Drug-induced Cushing's syndrome
0.648 0.352 0.000
I09 Other rheumatic heart diseases
0.648 0.352 0.000
S22.4 Multiple fractures of ribs
0.648 0.352 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.647 0.353 0.000
S51.0 Open wound of elbow
0.647 0.353 0.000
F13.2 Dependence syndrome
0.647 0.353 0.000
S52 Fracture of forearm
0.647 0.353 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.647 0.353 0.000
S37 Injury of urinary and pelvic organs
0.647 0.353 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.647 0.353 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.647 0.353 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.647 0.353 0.000
H44 Disorders of globe
0.646 0.354 0.000
I45.8 Other specified conduction disorders
0.646 0.354 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.645 0.354 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.645 0.354 0.000
T93.4 Sequelae of injury of nerve of lower limb
0.645 0.354 0.000
I10-I15 Hypertensive diseases
0.645 0.355 0.000
S17 Crushing injury of neck
0.644 0.356 0.000
S15 Injury of blood vessels at neck level
0.644 0.356 0.000
S18 Traumatic amputation at neck level
0.644 0.356 0.000
S16 Injury of muscle and tendon at neck level
0.644 0.356 0.000
T59 Toxic effect of other gases, fumes and vapours
0.644 0.356 0.000
T91.9 Sequelae of unspecified injury of neck and trunk
0.643 0.357 0.000
J33.1 Polypoid sinus degeneration
0.643 0.357 0.000
G30 Alzheimer's disease
0.643 0.357 0.000
M11.2 Other chondrocalcinosis
0.643 0.357 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.643 0.357 0.000
S59 Other and unspecified injuries of forearm
0.642 0.358 0.000
S58 Traumatic amputation of forearm
0.642 0.358 0.000
S57 Crushing injury of forearm
0.642 0.358 0.000
S55 Injury of blood vessels at forearm level
0.642 0.358 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.642 0.358 0.000
F99-F99 Unspecified mental disorder
0.642 0.358 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.642 0.358 0.000
I67 Other cerebrovascular diseases
0.641 0.359 0.000
M07.3 Other psoriatic arthropathies
0.640 0.360 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.640 0.360 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.639 0.361 0.000
I47 Paroxysmal tachycardia
0.639 0.361 0.000
Q61.9 Cystic kidney disease, unspecified
0.638 0.362 0.000
Q61.8 Other cystic kidney diseases
0.638 0.362 0.000
Q61.5 Medullary cystic kidney
0.638 0.362 0.000
Q61.4 Renal dysplasia
0.638 0.362 0.000
Q61.1 Polycystic kidney, infantile type
0.638 0.362 0.000
V10-V19 Pedal cyclist injured in transport accident
0.638 0.362 0.000
S70-S79 Injuries to the hip and thigh
0.637 0.363 0.000
I06 Rheumatic aortic valve diseases
0.637 0.363 0.000
L80 Vitiligo
0.636 0.364 0.000
T78 Adverse effects, not elsewhere classified
0.636 0.364 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.636 0.364 0.000
E63 Other nutritional deficiencies
0.636 0.364 0.000
E56 Other vitamin deficiencies
0.636 0.364 0.000
E51 Thiamine deficiency
0.636 0.364 0.000
E50 Vitamin A deficiency
0.636 0.364 0.000
E60 Dietary zinc deficiency
0.636 0.364 0.000
E59 Dietary selenium deficiency
0.636 0.364 0.000
E58 Dietary calcium deficiency
0.636 0.364 0.000
E54 Ascorbic acid deficiency
0.636 0.364 0.000
E52 Niacin deficiency [pellagra]
0.636 0.364 0.000
E11.6 With other specified complications
0.636 0.364 0.000
I33 Acute and subacute endocarditis
0.636 0.364 0.000
M10.90 Gout, unspecified (Multiple sites)
0.635 0.365 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.635 0.365 0.000
W00-W19 Falls
0.635 0.365 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.634 0.366 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.633 0.366 0.000
H30 Chorioretinal inflammation
0.633 0.366 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.633 0.367 0.000
J09-J18 Influenza and pneumonia
0.633 0.367 0.000
E61 Deficiency of other nutrient elements
0.633 0.367 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.632 0.368 0.000
M84 Disorders of continuity of bone
0.632 0.368 0.000
T91.3 Sequelae of injury of spinal cord
0.632 0.368 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.631 0.369 0.000
W50-W64 Exposure to animate mechanical forces
0.631 0.369 0.000
L91 Hypertrophic disorders of skin
0.631 0.369 0.000
H53 Visual disturbances
0.631 0.369 0.000
M10.96 Gout, unspecified (Lower leg)
0.630 0.370 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.630 0.370 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.629 0.370 0.000
I85.0 Oesophageal varices with bleeding
0.629 0.371 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.627 0.373 0.000
T25 Burn and corrosion of ankle and foot
0.626 0.374 0.000
T21 Burn and corrosion of trunk
0.626 0.374 0.000
S90 Superficial injury of ankle and foot
0.626 0.374 0.000
B15 Acute hepatitis A
0.626 0.374 0.000
I71 Aortic aneurysm and dissection
0.626 0.374 0.000
F10.9 Unspecified mental and behavioural disorder
0.625 0.375 0.000
J20-J22 Other acute lower respiratory infections
0.625 0.375 0.000
E11.8 With unspecified complications
0.625 0.375 0.000
F42 Obsessive-compulsive disorder
0.625 0.375 0.000
E14 Unspecified diabetes mellitus
0.625 0.375 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.624 0.376 0.000
M40-M43 Deforming dorsopathies
0.624 0.376 0.000
E26.0 Primary hyperaldosteronism
0.624 0.376 0.000
L94 Other localised connective tissue disorders
0.624 0.376 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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