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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17472393
log Bayes Factor = 7.45108
Chromosome 13   position 100,056,531  (GRCh37) Explore rs17472393 on Ensembl!
Variant rs17472393 is part of Cluster X0269

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.998 0.002 0.000
E11 Non-insulin-dependent diabetes mellitus
0.997 0.003 0.000
E11.9 Without complications
0.996 0.004 0.000
J44 Other chronic obstructive pulmonary disease
0.994 0.006 0.000
J45 Asthma
0.991 0.009 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.991 0.009 0.000
J45.9 Asthma, unspecified
0.988 0.012 0.000
J43 Emphysema
0.985 0.015 0.000
Chapter IX Diseases of the circulatory system
0.978 0.022 0.000
J84 Other interstitial pulmonary diseases
0.978 0.022 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.978 0.022 0.000
E70-E90 Metabolic disorders
0.967 0.033 0.000
J95-J99 Other diseases of the respiratory system
0.964 0.036 0.000
J43.9 Emphysema, unspecified
0.963 0.037 0.000
I60-I69 Cerebrovascular diseases
0.962 0.038 0.000
E16 Other disorders of pancreatic internal secretion
0.962 0.038 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.960 0.040 0.000
Chapter VI Diseases of the nervous system
0.959 0.041 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.955 0.045 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.948 0.052 0.000
I63 Cerebral infarction
0.946 0.054 0.000
Chapter VIII Diseases of the ear and mastoid process
0.941 0.059 0.000
J98 Other respiratory disorders
0.936 0.064 0.000
E20-E35 Disorders of other endocrine glands
0.935 0.065 0.000
I63.9 Cerebral infarction, unspecified
0.934 0.066 0.000
E16.2 Hypoglycaemia, unspecified
0.930 0.070 0.000
Chapter VII Diseases of the eye and adnexa
0.920 0.080 0.000
J98.4 Other disorders of lung
0.913 0.087 0.000
G90-G99 Other disorders of the nervous system
0.911 0.089 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.909 0.091 0.000
H65-H75 Diseases of middle ear and mastoid
0.904 0.096 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.895 0.105 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.893 0.107 0.000
H30-H36 Disorders of choroid and retina
0.893 0.107 0.000
J09-J18 Influenza and pneumonia
0.891 0.109 0.000
Chapter XX External causes of morbidity and mortality
0.884 0.116 0.000
E86 Volume depletion
0.883 0.117 0.000
E83 Disorders of mineral metabolism
0.883 0.117 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.878 0.122 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.870 0.130 0.000
E14 Unspecified diabetes mellitus
0.869 0.131 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.866 0.134 0.000
H35 Other retinal disorders
0.864 0.136 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.854 0.146 0.000
J43.2 Centrilobular emphysema
0.853 0.147 0.000
E16.1 Other hypoglycaemia
0.851 0.149 0.000
E83.4 Disorders of magnesium metabolism
0.846 0.154 0.000
I20-I25 Ischaemic heart diseases
0.844 0.156 0.000
E28 Ovarian dysfunction
0.842 0.158 0.000
I10-I15 Hypertensive diseases
0.840 0.160 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.839 0.161 0.000
J84.8 Other specified interstitial pulmonary diseases
0.833 0.167 0.000
H53-H54 Visual disturbances and blindness
0.830 0.170 0.000
E11.8 With unspecified complications
0.828 0.172 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.823 0.177 0.000
G12 Spinal muscular atrophy and related syndromes
0.821 0.179 0.000
H35.8 Other specified retinal disorders
0.814 0.186 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.811 0.188 0.000
G96 Other disorders of central nervous system
0.811 0.189 0.000
G95 Other diseases of spinal cord
0.810 0.190 0.000
H54 Blindness and low vision
0.806 0.194 0.000
J60-J70 Lung diseases due to external agents
0.802 0.197 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.800 0.200 0.000
Q80-Q89 Other congenital malformations
0.799 0.201 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.798 0.202 0.000
E78.0 Pure hypercholesterolaemia
0.797 0.203 0.000
H71 Cholesteatoma of middle ear
0.797 0.203 0.000
J42 Unspecified chronic bronchitis
0.796 0.204 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.794 0.206 0.000
I20 Angina pectoris
0.794 0.206 0.000
I69 Sequelae of cerebrovascular disease
0.793 0.207 0.000
H66 Suppurative and unspecified otitis media
0.793 0.207 0.000
J47 Bronchiectasis
0.793 0.207 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.790 0.210 0.000
I05-I09 Chronic rheumatic heart diseases
0.785 0.215 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.783 0.217 0.000
H60-H62 Diseases of external ear
0.780 0.220 0.000
G12.2 Motor neuron disease
0.779 0.221 0.000
I20.0 Unstable angina
0.779 0.221 0.000
J18 Pneumonia, organism unspecified
0.773 0.227 0.000
E40-E46 Malnutrition
0.769 0.231 0.000
I10 Essential (primary) hypertension
0.768 0.232 0.000
E11.5 With peripheral circulatory complications
0.767 0.233 0.000
H18 Other disorders of cornea
0.766 0.234 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.766 0.234 0.000
I65.2 Occlusion and stenosis of carotid artery
0.763 0.237 0.000
J80 Adult respiratory distress syndrome
0.762 0.238 0.000
E11.0 With coma
0.762 0.238 0.000
E21.3 Hyperparathyroidism, unspecified
0.760 0.240 0.000
Y45.0 Opioids and related analgesics
0.754 0.246 0.000
I24 Other acute ischaemic heart diseases
0.753 0.247 0.000
E28.2 Polycystic ovarian syndrome
0.752 0.248 0.000
J81 Pulmonary oedema
0.751 0.249 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.750 0.250 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.747 0.253 0.000
I62 Other nontraumatic intracranial haemorrhage
0.747 0.253 0.000
E11.1 With ketoacidosis
0.742 0.258 0.000
E11.2 With renal complications
0.742 0.258 0.000
H69 Other disorders of Eustachian tube
0.742 0.258 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.738 0.262 0.000
H15 Disorders of sclera
0.737 0.263 0.000
Y57 Other and unspecified drugs and medicaments
0.736 0.264 0.000
H35.9 Retinal disorder, unspecified
0.735 0.265 0.000
J98.1 Pulmonary collapse
0.735 0.265 0.000
H65 Nonsuppurative otitis media
0.734 0.266 0.000
H35.0 Background retinopathy and retinal vascular changes
0.732 0.268 0.000
H36 Retinal disorders in diseases classified elsewhere
0.730 0.270 0.000
I77 Other disorders of arteries and arterioles
0.730 0.270 0.000
E10 Insulin-dependent diabetes mellitus
0.730 0.270 0.000
G96.0 Cerebrospinal fluid leak
0.729 0.271 0.000
E14.3 With ophthalmic complications
0.727 0.273 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.727 0.273 0.000
J98.8 Other specified respiratory disorders
0.726 0.274 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.725 0.275 0.000
H60 Otitis externa
0.725 0.275 0.000
W50-W64 Exposure to animate mechanical forces
0.725 0.275 0.000
E65-E68 Obesity and other hyperalimentation
0.723 0.277 0.000
E78.8 Other disorders of lipoprotein metabolism
0.720 0.280 0.000
I65.1 Occlusion and stenosis of basilar artery
0.718 0.282 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.284 0.000
E11.7 With multiple complications
0.715 0.285 0.000
E74 Other disorders of carbohydrate metabolism
0.714 0.286 0.000
J18.0 Bronchopneumonia, unspecified
0.714 0.286 0.000
E00-E07 Disorders of thyroid gland
0.713 0.287 0.000
H35.4 Peripheral retinal degeneration
0.712 0.288 0.000
H54.0 Blindness, both eyes
0.712 0.288 0.000
J45.8 Mixed asthma
0.711 0.289 0.000
J45.1 Nonallergic asthma
0.711 0.289 0.000
H90-H95 Other disorders of ear
0.711 0.289 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.711 0.289 0.000
J69 Pneumonitis due to solids and liquids
0.711 0.289 0.000
E14.4 With neurological complications
0.710 0.290 0.000
H54.7 Unspecified visual loss
0.710 0.290 0.000
H31 Other disorders of choroid
0.709 0.291 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.709 0.291 0.000
I69.3 Sequelae of cerebral infarction
0.708 0.292 0.000
Q50-Q56 Congenital malformations of genital organs
0.707 0.293 0.000
J43.8 Other emphysema
0.706 0.294 0.000
J43.1 Panlobular emphysema
0.706 0.294 0.000
J43.0 MacLeod's syndrome
0.706 0.294 0.000
G95.2 Cord compression, unspecified
0.704 0.296 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.703 0.296 0.000
Chapter XXII Codes for special purposes
0.703 0.297 0.000
H74 Other disorders of middle ear and mastoid
0.702 0.298 0.000
I00-I02 Acute rheumatic fever
0.701 0.299 0.000
J84.0 Alveolar and parietoalveolar conditions
0.701 0.299 0.000
E15 Nondiabetic hypoglycaemic coma
0.701 0.299 0.000
E88 Other metabolic disorders
0.700 0.300 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.700 0.300 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.700 0.300 0.000
G91 Hydrocephalus
0.697 0.303 0.000
E83.5 Disorders of calcium metabolism
0.695 0.305 0.000
E78.4 Other hyperlipidaemia
0.694 0.306 0.000
E84 Cystic fibrosis
0.693 0.307 0.000
E79 Disorders of purine and pyrimidine metabolism
0.693 0.307 0.000
E77 Disorders of glycoprotein metabolism
0.693 0.307 0.000
E76 Disorders of glycosaminoglycan metabolism
0.693 0.307 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.693 0.307 0.000
E72 Other disorders of amino-acid metabolism
0.693 0.307 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.693 0.307 0.000
E70 Disorders of aromatic amino-acid metabolism
0.693 0.307 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.693 0.307 0.000
I11 Hypertensive heart disease
0.693 0.307 0.000
J96 Respiratory failure, not elsewhere classified
0.691 0.309 0.000
Q00-Q07 Congenital malformations of the nervous system
0.691 0.309 0.000
E20 Hypoparathyroidism
0.691 0.309 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.690 0.310 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.690 0.310 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.690 0.310 0.000
E16.4 Abnormal secretion of gastrin
0.690 0.310 0.000
E16.3 Increased secretion of glucagon
0.690 0.310 0.000
I22 Subsequent myocardial infarction
0.689 0.311 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.688 0.312 0.000
H66.3 Other chronic suppurative otitis media
0.687 0.313 0.000
E27 Other disorders of adrenal gland
0.684 0.316 0.000
E29 Testicular dysfunction
0.683 0.317 0.000
Y00-Y09 Assault
0.682 0.318 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.682 0.318 0.000
X20-X29 Contact with venomous animals and plants
0.682 0.318 0.000
E83.3 Disorders of phosphorus metabolism
0.680 0.320 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.680 0.320 0.000
I63.8 Other cerebral infarction
0.680 0.320 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.679 0.321 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.679 0.321 0.000
Q85 Phakomatoses, not elsewhere classified
0.679 0.321 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.678 0.322 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.678 0.322 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.678 0.322 0.000
J98.6 Disorders of diaphragm
0.678 0.322 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.677 0.323 0.000
E85 Amyloidosis
0.674 0.326 0.000
J20-J22 Other acute lower respiratory infections
0.673 0.327 0.000
G70-G73 Diseases of myoneural junction and muscle
0.672 0.328 0.000
J98.3 Compensatory emphysema
0.671 0.329 0.000
J98.2 Interstitial emphysema
0.671 0.329 0.000
E23 Hypofunction and other disorders of pituitary gland
0.671 0.329 0.000
V01-V09 Pedestrian injured in transport accident
0.670 0.329 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.670 0.329 0.000
E32 Diseases of thymus
0.670 0.329 0.000
E31 Polyglandular dysfunction
0.670 0.329 0.000
E30 Disorders of puberty, not elsewhere classified
0.670 0.329 0.000
E25 Adrenogenital disorders
0.670 0.329 0.000
E24 Cushing's syndrome
0.670 0.329 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.670 0.330 0.000
J10 Influenza due to identified influenza virus
0.668 0.331 0.000
J00-J06 Acute upper respiratory infections
0.668 0.332 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.668 0.332 0.000
E28.3 Primary ovarian failure
0.667 0.332 0.000
H18.2 Other corneal oedema
0.666 0.334 0.000
I77.6 Arteritis, unspecified
0.665 0.335 0.000
H20 Iridocyclitis
0.662 0.338 0.000
E73 Lactose intolerance
0.662 0.338 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.660 0.340 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.659 0.341 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.659 0.341 0.000
Y44 Agents primarily affecting blood constituents
0.659 0.341 0.000
H54.4 Blindness, one eye
0.658 0.342 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.657 0.343 0.000
X50-X57 Overexertion, travel and privation
0.656 0.344 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.654 0.346 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.653 0.347 0.000
G92 Toxic encephalopathy
0.653 0.347 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.652 0.348 0.000
Q35-Q37 Cleft lip and cleft palate
0.652 0.348 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.652 0.348 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.650 0.350 0.000
G95.9 Disease of spinal cord, unspecified
0.650 0.350 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.649 0.351 0.000
H34 Retinal vascular occlusions
0.649 0.351 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.648 0.352 0.000
H70 Mastoiditis and related conditions
0.648 0.352 0.000
H68 Eustachian salpingitis and obstruction
0.648 0.352 0.000
H67 Otitis media in diseases classified elsewhere
0.648 0.352 0.000
H54.9 Unspecified visual impairment (binocular)
0.648 0.352 0.000
G93 Other disorders of brain
0.647 0.353 0.000
E78.5 Hyperlipidaemia, unspecified
0.646 0.354 0.000
H16 Keratitis
0.646 0.354 0.000
J18.1 Lobar pneumonia, unspecified
0.645 0.355 0.000
J69.0 Pneumonitis due to food and vomit
0.645 0.355 0.000
J11 Influenza, virus not identified
0.644 0.356 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.642 0.358 0.000
Q43 Other congenital malformations of intestine
0.642 0.358 0.000
V40-V49 Car occupant injured in transport accident
0.641 0.359 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.641 0.359 0.000
Y52 Agents primarily affecting the cardiovascular system
0.641 0.359 0.000
J46 Status asthmaticus
0.640 0.359 0.000
E78.6 Lipoprotein deficiency
0.640 0.359 0.000
E78.3 Hyperchylomicronaemia
0.640 0.359 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.640 0.359 0.000
E26 Hyperaldosteronism
0.640 0.360 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.640 0.360 0.000
H30 Chorioretinal inflammation
0.640 0.360 0.000
J17 Pneumonia in diseases classified elsewhere
0.639 0.361 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.639 0.361 0.000
J12 Viral pneumonia, not elsewhere classified
0.639 0.361 0.000
J14 Pneumonia due to Haemophilus influenzae
0.639 0.361 0.000
J09 Influenza due to certain identified influenza virus
0.639 0.361 0.000
V20-V29 Motorcycle rider injured in transport accident
0.639 0.361 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.638 0.361 0.000
H73 Other disorders of tympanic membrane
0.635 0.365 0.000
G90 Disorders of autonomic nervous system
0.634 0.365 0.000
J98.9 Respiratory disorder, unspecified
0.634 0.366 0.000
Y35-Y36 Legal intervention and operations of war
0.634 0.366 0.000
Y10-Y34 Event of undetermined intent
0.634 0.366 0.000
X85-X99 Assault
0.634 0.366 0.000
X30-X39 Exposure to forces of nature
0.634 0.366 0.000
X10-X19 Contact with heat and hot substances
0.634 0.366 0.000
X00-X09 Exposure to smoke, fire and flames
0.634 0.366 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.634 0.366 0.000
W75-W84 Other accidental threats to breathing
0.634 0.366 0.000
W65-W74 Accidental drowning and submersion
0.634 0.366 0.000
V98-V99 Other and unspecified transport accidents
0.634 0.366 0.000
V95-V97 Air and space transport accidents
0.634 0.366 0.000
V90-V94 Water transport accidents
0.634 0.366 0.000
V70-V79 Bus occupant injured in transport accident
0.634 0.366 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.634 0.366 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.634 0.366 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.634 0.366 0.000
E34 Other endocrine disorders
0.633 0.367 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.633 0.367 0.000
E83.8 Other disorders of mineral metabolism
0.633 0.367 0.000
E83.2 Disorders of zinc metabolism
0.633 0.367 0.000
E83.0 Disorders of copper metabolism
0.633 0.367 0.000
R50-R69 General symptoms and signs
0.633 0.367 0.000
E10.4 With neurological complications
0.631 0.369 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.631 0.369 0.000
E21.0 Primary hyperparathyroidism
0.631 0.369 0.000
I67 Other cerebrovascular diseases
0.630 0.370 0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.630 0.370 0.000
G11 Hereditary ataxia
0.630 0.370 0.000
G14 Postpolio syndrome
0.630 0.370 0.000
G10 Huntington's disease
0.630 0.370 0.000
E78.1 Pure hyperglyceridaemia
0.629 0.371 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.629 0.371 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.628 0.372 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.628 0.372 0.000
H55-H59 Other disorders of eye and adnexa
0.628 0.372 0.000
H43-H45 Disorders of vitreous body and globe
0.627 0.373 0.000
I78 Diseases of capillaries
0.625 0.375 0.000
Y57.5 X-ray contrast media
0.625 0.375 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.624 0.376 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.624 0.376 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.624 0.376 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.624 0.376 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.624 0.376 0.000
Q82 Other congenital malformations of skin
0.624 0.376 0.000
H60.0 Abscess of external ear
0.624 0.376 0.000
E14.8 With unspecified complications
0.623 0.377 0.000
E14.7 With multiple complications
0.623 0.377 0.000
E14.6 With other specified complications
0.623 0.377 0.000
E14.5 With peripheral circulatory complications
0.623 0.377 0.000
E14.2 Withrenal complications
0.623 0.377 0.000
E14.1 With ketoacidosis
0.623 0.377 0.000
E14.0 With coma
0.623 0.377 0.000
H66.9 Otitis media, unspecified
0.623 0.377 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.621 0.378 0.000
H60.5 Acute otitis externa, non-infective
0.621 0.379 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.621 0.379 0.000
Y43 Primarily systemic agents
0.621 0.379 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.621 0.379 0.000
G95.8 Other specified diseases of spinal cord
0.620 0.380 0.000
H35.2 Other proliferative retinopathy
0.620 0.380 0.000
H35.1 Retinopathy of prematurity
0.620 0.380 0.000
S20-S29 Injuries to the thorax
0.620 0.380 0.000
R53 Malaise and fatigue
0.620 0.380 0.000
E14.9 Without complications
0.619 0.381 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.618 0.382 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.618 0.382 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.617 0.383 0.000
E13 Other specified diabetes mellitus
0.616 0.384 0.000
J40 Bronchitis, not specified as acute or chronic
0.615 0.385 0.000
H36.0 Diabetic retinopathy
0.614 0.386 0.000
H69.9 Eustachian tube disorder, unspecified
0.613 0.387 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.612 0.388 0.000
Y59 Other and unspecified vaccines and biological substances
0.612 0.388 0.000
Y58 Bacterial vaccines
0.612 0.388 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.612 0.388 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.612 0.388 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.612 0.388 0.000
Y48 Anaesthetics and therapeutic gases
0.612 0.388 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.612 0.388 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.612 0.388 0.000
G03 Meningitis due to other and unspecified causes
0.611 0.388 0.000
H18.8 Other specified disorders of cornea
0.611 0.389 0.000
G96.1 Disorders of meninges, not elsewhere classified
0.610 0.390 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.608 0.392 0.000
I05 Rheumatic mitral valve diseases
0.608 0.392 0.000
R63 Symptoms and signs concerning food and fluid intake
0.607 0.393 0.000
H21 Other disorders of iris and ciliary body
0.607 0.393 0.000
E11.3 With ophthalmic complications
0.606 0.394 0.000
H15.0 Scleritis
0.606 0.394 0.000
V10-V19 Pedal cyclist injured in transport accident
0.606 0.394 0.000
I23 Certain current complications following acute myocardial infarction
0.605 0.394 0.000
Y45.2 Propionic acid derivatives
0.605 0.395 0.000
H18.5 Hereditary corneal dystrophies
0.605 0.395 0.000
H17 Corneal scars and opacities
0.604 0.395 0.000
E46 Unspecified protein-energy malnutrition
0.604 0.396 0.000
E28.9 Ovarian dysfunction, unspecified
0.604 0.396 0.000
E28.8 Other ovarian dysfunction
0.604 0.396 0.000
E28.1 Androgen excess
0.604 0.396 0.000
E28.0 Oestrogen excess
0.604 0.396 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.604 0.396 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.604 0.396 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.603 0.397 0.000
I24.1 Dressler's syndrome
0.603 0.397 0.000
I61 Intracerebral haemorrhage
0.603 0.397 0.000
I13 Hypertensive heart and renal disease
0.602 0.398 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.601 0.399 0.000
E21.4 Other specified disorders of parathyroid gland
0.601 0.399 0.000
E21.2 Other hyperparathyroidism
0.601 0.399 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.601 0.399 0.000
W55 Bitten or struck by other mammals
0.601 0.399 0.000
Q60-Q64 Congenital malformations of the urinary system
0.600 0.399 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.601 0.399 0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.597 0.403 0.000
R61 Hyperhidrosis
0.597 0.403 0.000
E78.2 Mixed hyperlipidaemia
0.596 0.403 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.595 0.405 0.000
G61 Inflammatory polyneuropathy
0.595 0.405 0.000
Y40 Systemic antibiotics
0.593 0.407 0.000
R63.0 Anorexia
0.593 0.407 0.000
E22 Hyperfunction of pituitary gland
0.593 0.407 0.000
J15.1 Pneumonia due to Pseudomonas
0.592 0.408 0.000
I77.1 Stricture of artery
0.591 0.409 0.000
T93 Sequelae of injuries of lower limb
0.590 0.410 0.000
I20.1 Angina pectoris with documented spasm
0.590 0.410 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.590 0.410 0.000
G00 Bacterial meningitis, not elsewhere classified
0.590 0.410 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.590 0.410 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.590 0.410 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.590 0.410 0.000
H15.1 Episcleritis
0.590 0.410 0.000
G12.9 Spinal muscular atrophy, unspecified
0.588 0.412 0.000
G12.8 Other spinal muscular atrophies and related syndromes
0.588 0.412 0.000
G12.1 Other inherited spinal muscular atrophy
0.588 0.412 0.000
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.588 0.412 0.000
I08 Multiple valve diseases
0.588 0.412 0.000
H65.3 Chronic mucoid otitis media
0.588 0.412 0.000
I07 Rheumatic tricuspid valve diseases
0.588 0.412 0.000
H35.6 Retinal haemorrhage
0.587 0.413 0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.587 0.413 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.587 0.413 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.586 0.414 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.585 0.415 0.000
Q39 Congenital malformations of oesophagus
0.584 0.416 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.584 0.416 0.000
G96.9 Disorder of central nervous system, unspecified
0.582 0.418 0.000
G96.8 Other specified disorders of central nervous system
0.582 0.418 0.000
E11.6 With other specified complications
0.581 0.419 0.000
V80-V89 Other land transport accidents
0.581 0.419 0.000
G95.0 Syringomyelia and syringobulbia
0.581 0.419 0.000
I70 Atherosclerosis
0.581 0.419 0.000
E11.4 With neurological complications
0.581 0.419 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.580 0.420 0.000
E04 Other non-toxic goitre
0.580 0.420 0.000
H10-H13 Disorders of conjunctiva
0.580 0.420 0.000
R05 Cough
0.580 0.420 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.579 0.421 0.000
Y57.9 Drug or medicament, unspecified
0.579 0.421 0.000
H54.6 Unqualified visual loss, one eye
0.578 0.422 0.000
H54.5 Low vision, one eye
0.578 0.422 0.000
H54.3 Unqualified visual loss, both eyes
0.578 0.422 0.000
H54.2 Low vision, both eyes
0.578 0.422 0.000
H54.1 Blindness, one eye, low vision, other eye
0.578 0.422 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.576 0.424 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.576 0.424 0.000
J70 Respiratory conditions due to other external agents
0.575 0.424 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.575 0.424 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.575 0.424 0.000
J66 Airway disease due to specific organic dust
0.575 0.424 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.575 0.424 0.000
J62 Pneumoconiosis due to dust containing silica
0.575 0.424 0.000
J65 Pneumoconiosis associated with tuberculosis
0.575 0.424 0.000
J64 Unspecified pneumoconiosis
0.575 0.424 0.000
J60 Coalworker's pneumoconiosis
0.575 0.424 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.574 0.426 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.574 0.426 0.000
Y45.8 Other analgesics and antipyretics
0.574 0.426 0.000
Y45.5 4-Aminophenol derivatives
0.574 0.426 0.000
Y45.4 Antirheumatics
0.574 0.426 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.573 0.427 0.000
Q84 Other congenital malformations of integument
0.573 0.427 0.000
Q83 Congenital malformations of breast
0.573 0.427 0.000
Q81 Epidermolysis bullosa
0.573 0.427 0.000
Q80 Congenital ichthyosis
0.573 0.427 0.000
J95.9 Postprocedural respiratory disorder, unspecified
0.572 0.427 0.000
G54 Nerve root and plexus disorders
0.572 0.428 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.572 0.428 0.000
T93.2 Sequelae of other fractures of lower limb
0.572 0.428 0.000
W00-W19 Falls
0.571 0.429 0.000
R01 Cardiac murmurs and other cardiac sounds
0.570 0.430 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.569 0.431 0.000
H66.4 Suppurative otitis media, unspecified
0.568 0.432 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.568 0.432 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.568 0.432 0.000
H66.0 Acute suppurative otitis media
0.568 0.432 0.000
I71 Aortic aneurysm and dissection
0.568 0.432 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.567 0.433 0.000
H31.0 Chorioretinal scars
0.566 0.434 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.566 0.434 0.000
J86 Pyothorax
0.566 0.434 0.000
G51 Facial nerve disorders
0.566 0.434 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.566 0.434 0.000
G40-G47 Episodic and paroxysmal disorders
0.565 0.435 0.000
I77.0 Arteriovenous fistula, acquired
0.564 0.436 0.000
H60.3 Other infective otitis externa
0.564 0.436 0.000
J00 Acute nasopharyngitis [common cold]
0.563 0.437 0.000
I09 Other rheumatic heart diseases
0.563 0.437 0.000
I06 Rheumatic aortic valve diseases
0.563 0.437 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.562 0.438 0.000
Q85.8 Other phakomatoses, not elsewhere classified
0.561 0.439 0.000
H35.7 Separation of retinal layers
0.560 0.440 0.000
Q51 Congenital malformations of uterus and cervix
0.560 0.440 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.560 0.440 0.000
I24.8 Other forms of acute ischaemic heart disease
0.560 0.440 0.000
I60 Subarachnoid haemorrhage
0.559 0.441 0.000
H74.1 Adhesive middle ear disease
0.559 0.441 0.000
S22.4 Multiple fractures of ribs
0.558 0.442 0.000
H35.3 Degeneration of macula and posterior pole
0.557 0.443 0.000
Q89 Other congenital malformations, not elsewhere classified
0.557 0.443 0.000
H60.9 Otitis externa, unspecified
0.556 0.444 0.000
I15 Secondary hypertension
0.555 0.445 0.000
R61.9 Hyperhidrosis, unspecified
0.555 0.445 0.000
J18.8 Other pneumonia, organism unspecified
0.554 0.446 0.000
J18.2 Hypostatic pneumonia, unspecified
0.554 0.446 0.000
H69.8 Other specified disorders of Eustachian tube
0.553 0.447 0.000
H35.5 Hereditary retinal dystrophy
0.553 0.447 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.552 0.448 0.000
E45 Retarded development following protein-energy malnutrition
0.552 0.448 0.000
E43 Unspecified severe protein-energy malnutrition
0.552 0.448 0.000
E42 Marasmic kwashiorkor
0.552 0.448 0.000
E41 Nutritional marasmus
0.552 0.448 0.000
E40 Kwashiorkor
0.552 0.448 0.000
I22.8 Subsequent myocardial infarction of other sites
0.551 0.449 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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