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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17528414
log Bayes Factor = 17.7734
Chromosome 12   position 32,352,055  (GRCh37) Explore rs17528414 on Ensembl!
Variant rs17528414 is part of Cluster X0197

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
E70-E90 Metabolic disorders
0.997 0.003 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.997 0.003 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.995 0.005 0.000
Chapter XX External causes of morbidity and mortality
0.994 0.006 0.000
L89 Decubitus ulcer
0.994 0.006 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.990 0.010 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.989 0.011 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.989 0.011 0.000
Chapter XXI Factors influencing health status and contact with health services
0.988 0.012 0.000
R60.0 Localised oedema
0.988 0.012 0.000
R50-R69 General symptoms and signs
0.988 0.012 0.000
S00-S09 Injuries to the head
0.988 0.012 0.000
R60 Oedema, not elsewhere classified
0.988 0.012 0.000
Chapter VIII Diseases of the ear and mastoid process
0.987 0.013 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.983 0.017 0.000
S01 Open wound of head
0.976 0.024 0.000
Z51 Other medical care
0.976 0.024 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.975 0.025 0.000
Z51.0 Radiotherapy session
0.974 0.026 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.972 0.028 0.000
Z51.5 Palliative care
0.969 0.031 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.966 0.034 0.000
H65-H75 Diseases of middle ear and mastoid
0.964 0.036 0.000
F41 Other anxiety disorders
0.963 0.037 0.000
L08 Other local infections of skin and subcutaneous tissue
0.962 0.038 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.962 0.038 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.960 0.040 0.000
R40 Somnolence, stupor and coma
0.956 0.044 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.955 0.045 0.000
R40.2 Coma, unspecified
0.950 0.050 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.949 0.051 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.948 0.052 0.000
F41.2 Mixed anxiety and depressive disorder
0.948 0.052 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.946 0.054 0.000
E83 Disorders of mineral metabolism
0.944 0.056 0.000
R53 Malaise and fatigue
0.943 0.057 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.942 0.058 0.000
W00-W19 Falls
0.940 0.060 0.000
L60-L75 Disorders of skin appendages
0.939 0.061 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.936 0.064 0.000
E86 Volume depletion
0.935 0.065 0.000
Z60 Problems related to social environment
0.935 0.065 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.932 0.068 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.932 0.068 0.000
Chapter X Diseases of the respiratory system
0.931 0.069 0.000
L50-L54 Urticaria and erythema
0.931 0.069 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.931 0.069 0.000
J44 Other chronic obstructive pulmonary disease
0.931 0.069 0.000
J40-J47 Chronic lower respiratory diseases
0.930 0.070 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.926 0.074 0.000
R47-R49 Symptoms and signs involving speech and voice
0.924 0.076 0.000
E83.5 Disorders of calcium metabolism
0.923 0.077 0.000
S10-S19 Injuries to the neck
0.922 0.078 0.000
Q60-Q64 Congenital malformations of the urinary system
0.918 0.082 0.000
F30-F39 Mood [affective] disorders
0.917 0.083 0.000
Z60.2 Living alone
0.917 0.083 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.915 0.085 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.914 0.086 0.000
H66 Suppurative and unspecified otitis media
0.909 0.091 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.908 0.092 0.000
L89.2 Stage III decubitus ulcer
0.903 0.097 0.000
R47 Speech disturbances, not elsewhere classified
0.902 0.098 0.000
H60-H62 Diseases of external ear
0.901 0.099 0.000
S00 Superficial injury of head
0.897 0.103 0.000
S01.4 Open wound of cheek and temporomandibular area
0.896 0.104 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.895 0.105 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.894 0.106 0.000
E89.0 Postprocedural hypothyroidism
0.890 0.110 0.000
E40-E46 Malnutrition
0.888 0.112 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.887 0.113 0.000
L60 Nail disorders
0.886 0.114 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.886 0.114 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.885 0.115 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.883 0.117 0.000
S01.0 Open wound of scalp
0.881 0.119 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.880 0.120 0.000
S01.3 Open wound of ear
0.877 0.123 0.000
L89.1 Stage II decubitus ulcer
0.875 0.125 0.000
R63 Symptoms and signs concerning food and fluid intake
0.873 0.127 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.872 0.128 0.000
J42 Unspecified chronic bronchitis
0.871 0.129 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.871 0.129 0.000
L20-L30 Dermatitis and eczema
0.870 0.130 0.000
M20-M25 Other joint disorders
0.869 0.131 0.000
Q80-Q89 Other congenital malformations
0.869 0.131 0.000
S70-S79 Injuries to the hip and thigh
0.868 0.132 0.000
M20 Acquired deformities of fingers and toes
0.866 0.134 0.000
L53 Other erythematous conditions
0.864 0.136 0.000
E87.7 Fluid overload
0.863 0.137 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.863 0.137 0.000
H66.9 Otitis media, unspecified
0.862 0.138 0.000
T43.2 Other and unspecified antidepressants
0.860 0.140 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.860 0.140 0.000
Z73 Problems related to life-management difficulty
0.859 0.141 0.000
Z75 Problems related to medical facilities and other health care
0.859 0.141 0.000
M20.5 Other deformities of toe(s) (acquired)
0.857 0.143 0.000
R47.0 Dysphasia and aphasia
0.857 0.143 0.000
F60-F69 Disorders of adult personality and behaviour
0.856 0.144 0.000
F10.2 Dependence syndrome
0.856 0.144 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.855 0.145 0.000
W19 Unspecified fall
0.855 0.145 0.000
S00.8 Superficial injury of other parts of head
0.851 0.149 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.850 0.150 0.000
F10.0 Acute intoxication
0.848 0.152 0.000
Y52 Agents primarily affecting the cardiovascular system
0.847 0.153 0.000
X60-X84 Intentional self-harm
0.845 0.155 0.000
R45 Symptoms and signs involving emotional state
0.844 0.156 0.000
Z51.8 Other specified medical care
0.844 0.156 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.842 0.158 0.000
L91 Hypertrophic disorders of skin
0.842 0.158 0.000
L81 Other disorders of pigmentation
0.842 0.158 0.000
Q61 Cystic kidney disease
0.840 0.160 0.000
Z49 Care involving dialysis
0.840 0.160 0.000
R68 Other general symptoms and signs
0.839 0.161 0.000
H71 Cholesteatoma of middle ear
0.839 0.161 0.000
E87.0 Hyperosmolality and hypernatraemia
0.834 0.166 0.000
E20-E35 Disorders of other endocrine glands
0.832 0.168 0.000
R54 Senility
0.829 0.171 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.824 0.176 0.000
S01.9 Open wound of head, part unspecified
0.823 0.177 0.000
F99-F99 Unspecified mental disorder
0.821 0.179 0.000
L53.9 Erythematous condition, unspecified
0.820 0.180 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.818 0.182 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.816 0.184 0.000
H70 Mastoiditis and related conditions
0.816 0.184 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.816 0.184 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.813 0.187 0.000
S90-S99 Injuries to the ankle and foot
0.812 0.188 0.000
E46 Unspecified protein-energy malnutrition
0.809 0.191 0.000
E10-E14 Diabetes mellitus
0.808 0.192 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.805 0.195 0.000
W19.9 Unspecified place
0.805 0.195 0.000
M86-M90 Other osteopathies
0.803 0.197 0.000
Z74 Problems related to care-provider dependency
0.802 0.198 0.000
L94 Other localised connective tissue disorders
0.800 0.200 0.000
R47.1 Dysarthria and anarthria
0.799 0.201 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.798 0.202 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.797 0.203 0.000
L60.2 Onychogryphosis
0.797 0.203 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.795 0.205 0.000
R63.0 Anorexia
0.795 0.205 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.794 0.206 0.000
T21 Burn and corrosion of trunk
0.792 0.208 0.000
E87.6 Hypokalaemia
0.792 0.208 0.000
T66-T78 Other and unspecified effects of external causes
0.791 0.209 0.000
J46 Status asthmaticus
0.790 0.210 0.000
R57 Shock, not elsewhere classified
0.790 0.210 0.000
Z73.9 Problem related to life-management difficulty, unspecified
0.790 0.210 0.000
H60 Otitis externa
0.789 0.211 0.000
S19 Other and unspecified injuries of neck
0.788 0.212 0.000
L91.8 Other hypertrophic disorders of skin
0.788 0.212 0.000
F40 Phobic anxiety disorders
0.786 0.214 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.782 0.218 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.778 0.222 0.000
Q61.3 Polycystic kidney, unspecified
0.778 0.222 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.777 0.223 0.000
F41.1 Generalised anxiety disorder
0.777 0.223 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.775 0.225 0.000
L60.0 Ingrowing nail
0.773 0.227 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.773 0.227 0.000
E85 Amyloidosis
0.772 0.228 0.000
L04 Acute lymphadenitis
0.771 0.229 0.000
T79-T79 Certain early complications of trauma
0.771 0.229 0.000
L93 Lupus erythematosus
0.770 0.230 0.000
M34 Systemic sclerosis
0.769 0.231 0.000
W07 Fall involving chair
0.769 0.231 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.768 0.232 0.000
S72 Fracture of femur
0.767 0.232 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.767 0.233 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.767 0.233 0.000
T00-T07 Injuries involving multiple body regions
0.767 0.233 0.000
M33 Dermatopolymyositis
0.765 0.235 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.764 0.236 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.764 0.236 0.000
T51 Toxic effect of alcohol
0.762 0.238 0.000
Z51.9 Medical care, unspecified
0.762 0.238 0.000
H61 Other disorders of external ear
0.762 0.238 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.760 0.240 0.000
V01-V09 Pedestrian injured in transport accident
0.760 0.240 0.000
Z49.1 Extracorporeal dialysis
0.760 0.240 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.760 0.240 0.000
Q40 Other congenital malformations of upper alimentary tract
0.760 0.240 0.000
E89.2 Postprocedural hypoparathyroidism
0.758 0.242 0.000
Z50 Care involving use of rehabilitation procedures
0.758 0.242 0.000
E65-E68 Obesity and other hyperalimentation
0.757 0.243 0.000
F80-F89 Disorders of psychological development
0.754 0.245 0.000
F44 Dissociative [conversion] disorders
0.754 0.246 0.000
V40-V49 Car occupant injured in transport accident
0.753 0.246 0.000
L50 Urticaria
0.753 0.247 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.752 0.248 0.000
F11 Mental and behavioural disorders due to use of opioids
0.751 0.249 0.000
M89 Other disorders of bone
0.751 0.249 0.000
L10-L14 Bullous disorders
0.751 0.249 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.751 0.249 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.750 0.250 0.000
F34 Persistent mood [affective] disorders
0.750 0.250 0.000
F29 Unspecified nonorganic psychosis
0.750 0.250 0.000
Z75.5 Holiday relief care
0.749 0.251 0.000
M80-M85 Disorders of bone density and structure
0.749 0.251 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.748 0.252 0.000
E21.3 Hyperparathyroidism, unspecified
0.747 0.253 0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.747 0.253 0.000
Y57 Other and unspecified drugs and medicaments
0.746 0.254 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.746 0.254 0.000
Z76 Persons encountering health services in other circumstances
0.744 0.256 0.000
L89.3 Stage IV decubitus ulcer
0.744 0.256 0.000
Q82 Other congenital malformations of skin
0.743 0.257 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.743 0.257 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.743 0.257 0.000
E83.4 Disorders of magnesium metabolism
0.742 0.258 0.000
X10-X19 Contact with heat and hot substances
0.740 0.260 0.000
R64 Cachexia
0.739 0.261 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.739 0.261 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.738 0.262 0.000
F30 Manic episode
0.738 0.262 0.000
Z63 Other problems related to primary support group, including family circumstances
0.738 0.262 0.000
F60 Specific personality disorders
0.738 0.262 0.000
W17 Other fall from one level to another
0.737 0.263 0.000
S01.2 Open wound of nose
0.736 0.264 0.000
L29 Pruritus
0.736 0.264 0.000
S01.8 Open wound of other parts of head
0.735 0.265 0.000
S40-S49 Injuries to the shoulder and upper arm
0.735 0.265 0.000
V20-V29 Motorcycle rider injured in transport accident
0.734 0.266 0.000
F41.9 Anxiety disorder, unspecified
0.734 0.266 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.734 0.266 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.732 0.268 0.000
S10 Superficial injury of neck
0.732 0.268 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.731 0.269 0.000
Z50.2 Alcohol rehabilitation
0.731 0.269 0.000
Y44 Agents primarily affecting blood constituents
0.731 0.269 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.731 0.269 0.000
T14 Injury of unspecified body region
0.731 0.269 0.000
E89.3 Postprocedural hypopituitarism
0.730 0.270 0.000
F32 Depressive episode
0.729 0.271 0.000
H74 Other disorders of middle ear and mastoid
0.729 0.271 0.000
E00-E07 Disorders of thyroid gland
0.728 0.272 0.000
E11 Non-insulin-dependent diabetes mellitus
0.728 0.272 0.000
J81 Pulmonary oedema
0.727 0.273 0.000
H90-H95 Other disorders of ear
0.726 0.274 0.000
Z40 Prophylactic surgery
0.726 0.274 0.000
R63.1 Polydipsia
0.724 0.276 0.000
F45 Somatoform disorders
0.724 0.276 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.724 0.276 0.000
T42.4 Benzodiazepines
0.723 0.277 0.000
T36 Poisoning by systemic antibiotics
0.722 0.278 0.000
R60.9 Oedema, unspecified
0.721 0.279 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.721 0.279 0.000
T56 Toxic effect of metals
0.721 0.279 0.000
F33 Recurrent depressive disorder
0.720 0.280 0.000
R45.0 Nervousness
0.720 0.280 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.719 0.281 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.718 0.281 0.000
R45.2 Unhappiness
0.718 0.282 0.000
E74 Other disorders of carbohydrate metabolism
0.718 0.282 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
R68.8 Other specified general symptoms and signs
0.717 0.283 0.000
F25 Schizoaffective disorders
0.716 0.284 0.000
Z47 Other orthopaedic follow-up care
0.716 0.284 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.715 0.285 0.000
E84 Cystic fibrosis
0.715 0.285 0.000
E79 Disorders of purine and pyrimidine metabolism
0.715 0.285 0.000
E77 Disorders of glycoprotein metabolism
0.715 0.285 0.000
E76 Disorders of glycosaminoglycan metabolism
0.715 0.285 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.715 0.285 0.000
E72 Other disorders of amino-acid metabolism
0.715 0.285 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.715 0.285 0.000
E70 Disorders of aromatic amino-acid metabolism
0.715 0.285 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.715 0.285 0.000
S70 Superficial injury of hip and thigh
0.715 0.285 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.715 0.285 0.000
L87 Transepidermal elimination disorders
0.715 0.285 0.000
L88 Pyoderma gangrenosum
0.715 0.285 0.000
L86 Keratoderma in diseases classified elsewhere
0.715 0.285 0.000
L80 Vitiligo
0.715 0.285 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.714 0.286 0.000
W05 Fall involving wheelchair
0.714 0.286 0.000
Z74.0 Reduced mobility
0.714 0.286 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.713 0.287 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.713 0.287 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.713 0.287 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.713 0.287 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.287 0.000
Y10-Y34 Event of undetermined intent
0.713 0.287 0.000
X85-X99 Assault
0.713 0.287 0.000
X30-X39 Exposure to forces of nature
0.713 0.287 0.000
X00-X09 Exposure to smoke, fire and flames
0.713 0.287 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.713 0.287 0.000
W75-W84 Other accidental threats to breathing
0.713 0.287 0.000
W65-W74 Accidental drowning and submersion
0.713 0.287 0.000
V98-V99 Other and unspecified transport accidents
0.713 0.287 0.000
V95-V97 Air and space transport accidents
0.713 0.287 0.000
V90-V94 Water transport accidents
0.713 0.287 0.000
V70-V79 Bus occupant injured in transport accident
0.713 0.287 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.287 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.713 0.287 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.287 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.712 0.288 0.000
W13 Fall from, out of or through building or structure
0.712 0.288 0.000
F42 Obsessive-compulsive disorder
0.711 0.289 0.000
S06 Intracranial injury
0.710 0.290 0.000
Y40 Systemic antibiotics
0.710 0.290 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.710 0.290 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.709 0.291 0.000
Q35-Q37 Cleft lip and cleft palate
0.709 0.291 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.709 0.291 0.000
L01 Impetigo
0.709 0.291 0.000
L00 Staphylococcal scalded skin syndrome
0.709 0.291 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.708 0.292 0.000
R62 Lack of expected normal physiological development
0.708 0.292 0.000
Z57 Occupational exposure to risk-factors
0.708 0.292 0.000
S08 Traumatic amputation of part of head
0.708 0.292 0.000
S07 Crushing injury of head
0.708 0.292 0.000
S04 Injury of cranial nerves
0.708 0.292 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.708 0.292 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.707 0.293 0.000
T11 Other injuries of upper limb, level unspecified
0.707 0.293 0.000
E88 Other metabolic disorders
0.707 0.293 0.000
R46 Symptoms and signs involving appearance and behaviour
0.706 0.294 0.000
F48 Other neurotic disorders
0.705 0.295 0.000
Q50-Q56 Congenital malformations of genital organs
0.704 0.295 0.000
Q00-Q07 Congenital malformations of the nervous system
0.704 0.296 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.704 0.296 0.000
Y00-Y09 Assault
0.704 0.296 0.000
L05 Pilonidal cyst
0.704 0.296 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.703 0.297 0.000
J40 Bronchitis, not specified as acute or chronic
0.703 0.297 0.000
R58 Haemorrhage, not elsewhere classified
0.702 0.298 0.000
F10.5 Psychotic disorder
0.702 0.298 0.000
J84 Other interstitial pulmonary diseases
0.702 0.298 0.000
D80-D89 Certain disorders involving the immune mechanism
0.701 0.299 0.000
S31 Open wound of abdomen, lower back and pelvis
0.701 0.299 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.701 0.299 0.000
Z51.6 Desensitisation to allergens
0.699 0.300 0.000
Y59 Other and unspecified vaccines and biological substances
0.699 0.301 0.000
Y58 Bacterial vaccines
0.699 0.301 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.699 0.301 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.699 0.301 0.000
Y48 Anaesthetics and therapeutic gases
0.699 0.301 0.000
R43 Disturbances of smell and taste
0.699 0.301 0.000
S05 Injury of eye and orbit
0.698 0.301 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.698 0.302 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.698 0.302 0.000
Q12 Congenital lens malformations
0.697 0.303 0.000
Z44 Fitting and adjustment of external prosthetic device
0.697 0.303 0.000
Q85 Phakomatoses, not elsewhere classified
0.697 0.303 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.697 0.303 0.000
L83 Acanthosis nigricans
0.696 0.303 0.000
H66.3 Other chronic suppurative otitis media
0.696 0.303 0.000
Z64 Problems related to certain psychosocial circumstances
0.696 0.304 0.000
L65 Other nonscarring hair loss
0.696 0.304 0.000
S32 Fracture of lumbar spine and pelvis
0.696 0.304 0.000
H60.1 Cellulitis of external ear
0.696 0.304 0.000
F99 Mental disorder, not otherwise specified
0.694 0.306 0.000
R60.1 Generalised oedema
0.693 0.307 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.692 0.308 0.000
M40-M43 Deforming dorsopathies
0.692 0.308 0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
0.691 0.309 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.691 0.309 0.000
H68 Eustachian salpingitis and obstruction
0.691 0.309 0.000
H67 Otitis media in diseases classified elsewhere
0.691 0.309 0.000
F41.8 Other specified anxiety disorders
0.691 0.309 0.000
F41.3 Other mixed anxiety disorders
0.691 0.309 0.000
H73 Other disorders of tympanic membrane
0.690 0.309 0.000
E21.0 Primary hyperparathyroidism
0.690 0.310 0.000
L81.9 Disorder of pigmentation, unspecified
0.690 0.310 0.000
L08.1 Erythrasma
0.690 0.310 0.000
L08.0 Pyoderma
0.690 0.310 0.000
F32.9 Depressive episode, unspecified
0.689 0.311 0.000
W50-W64 Exposure to animate mechanical forces
0.689 0.311 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.689 0.311 0.000
S12 Fracture of neck
0.689 0.311 0.000
Z65 Problems related to other psychosocial circumstances
0.688 0.312 0.000
Z62 Other problems related to upbringing
0.688 0.312 0.000
Z61 Problems related to negative life events in childhood
0.688 0.312 0.000
Z59 Problems related to housing and economic circumstances
0.688 0.312 0.000
Z55 Problems related to education and literacy
0.688 0.312 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.688 0.312 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.687 0.313 0.000
M20.3 Other deformity of hallux (acquired)
0.687 0.313 0.000
L21 Seborrhoeic dermatitis
0.686 0.314 0.000
R40.1 Stupor
0.686 0.314 0.000
Z58 Problems related to physical environment
0.685 0.315 0.000
L60.9 Nail disorder, unspecified
0.685 0.315 0.000
S72.4 Fracture of lower end of femur
0.685 0.315 0.000
Y43 Primarily systemic agents
0.685 0.315 0.000
R57.2 Septic shock
0.685 0.315 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.685 0.315 0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.685 0.315 0.000
Z75.3 Unavailability and inaccessibility of health-care facilities
0.685 0.315 0.000
H65 Nonsuppurative otitis media
0.684 0.316 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.683 0.317 0.000
Chapter I Certain infectious and parasitic diseases
0.683 0.317 0.000
W08 Fall involving other furniture
0.683 0.317 0.000
M89.9 Disorder of bone, unspecified
0.682 0.318 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.682 0.318 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.682 0.318 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.681 0.319 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.680 0.319 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.680 0.319 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.680 0.319 0.000
E89.5 Postprocedural testicular hypofunction
0.680 0.319 0.000
E89.4 Postprocedural ovarian failure
0.680 0.319 0.000
E89.1 Postprocedural hypoinsulinaemia
0.680 0.319 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.680 0.320 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.680 0.320 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.680 0.320 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.680 0.320 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.680 0.320 0.000
R47.8 Other and unspecified speech disturbances
0.680 0.320 0.000
M24 Other specific joint derangements
0.679 0.321 0.000
T43.9 Psychotropic drug, unspecified
0.678 0.322 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.678 0.322 0.000
T43.6 Psychostimulants with abuse potential
0.678 0.322 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.678 0.322 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.678 0.322 0.000
E13 Other specified diabetes mellitus
0.678 0.322 0.000
F31 Bipolar affective disorder
0.678 0.322 0.000
M00-M03 Infectious arthropathies
0.677 0.322 0.000
Q63 Other congenital malformations of kidney
0.677 0.323 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.677 0.323 0.000
Y53.1 Other antacids and anti-gastric-secretion drugs
0.677 0.323 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.677 0.323 0.000
E83.8 Other disorders of mineral metabolism
0.677 0.323 0.000
E83.2 Disorders of zinc metabolism
0.677 0.323 0.000
E83.0 Disorders of copper metabolism
0.677 0.323 0.000
R29.6 Tendency to fall, not elsewhere classified
0.677 0.323 0.000
L72.1 Trichilemmal cyst
0.677 0.323 0.000
M60-M63 Disorders of muscles
0.676 0.324 0.000
L25 Unspecified contact dermatitis
0.676 0.324 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.676 0.324 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.675 0.325 0.000
M31 Other necrotising vasculopathies
0.674 0.326 0.000
H72 Perforation of tympanic membrane
0.674 0.326 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.674 0.326 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.674 0.326 0.000
W15 Fall from cliff
0.674 0.326 0.000
W14 Fall from tree
0.674 0.326 0.000
W12 Fall on and from scaffolding
0.674 0.326 0.000
W11 Fall on and from ladder
0.674 0.326 0.000
W09 Fall involving playground equipment
0.674 0.326 0.000
W04 Fall while being carried or supported by other persons
0.674 0.326 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.674 0.326 0.000
W00 Fall on same level involving ice and snow
0.674 0.326 0.000
L75 Apocrine sweat disorders
0.673 0.327 0.000
L74 Eccrine sweat disorders
0.673 0.327 0.000
L70 Acne
0.673 0.327 0.000
L68 Hypertrichosis
0.673 0.327 0.000
L67 Hair colour and hair shaft abnormalities
0.673 0.327 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.673 0.327 0.000
L64 Androgenic alopecia
0.673 0.327 0.000
L63 Alopecia areata
0.673 0.327 0.000
L62 Nail disorders in diseases classified elsewhere
0.673 0.327 0.000
W18 Other fall on same level
0.673 0.327 0.000
Chapter XXII Codes for special purposes
0.672 0.328 0.000
M33.2 Polymyositis
0.671 0.329 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.671 0.329 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.671 0.329 0.000
H70.8 Other mastoiditis and related conditions
0.671 0.329 0.000
S72.0 Fracture of neck of femur
0.671 0.329 0.000
Q61.2 Polycystic kidney, adult type
0.671 0.329 0.000
Z60.9 Problem related to social environment, unspecified
0.670 0.330 0.000
Z60.8 Other problems related to social environment
0.670 0.330 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.670 0.330 0.000
Z60.4 Social exclusion and rejection
0.670 0.330 0.000
Z60.3 Acculturation difficulty
0.670 0.330 0.000
Z60.1 Atypical parenting situation
0.670 0.330 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.670 0.330 0.000
M20.0 Deformity of finger(s)
0.670 0.330 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.670 0.330 0.000
Z56 Problems related to employment and unemployment
0.670 0.330 0.000
F23 Acute and transient psychotic disorders
0.670 0.330 0.000
W06 Fall involving bed
0.669 0.331 0.000
R40.0 Somnolence
0.669 0.331 0.000
S36 Injury of intra-abdominal organs
0.669 0.331 0.000
L73 Other follicular disorders
0.669 0.331 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.668 0.332 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.668 0.332 0.000
T42.3 Barbiturates
0.668 0.332 0.000
T42.2 Succinimides and oxazolidinediones
0.668 0.332 0.000
T42.1 Iminostilbenes
0.668 0.332 0.000
T42.0 Hydantoin derivatives
0.668 0.332 0.000
Z52 Donors of organs and tissues
0.668 0.332 0.000
E87.4 Mixed disorder of acid-base balance
0.668 0.332 0.000
W07.0 Home
0.668 0.332 0.000
V80-V89 Other land transport accidents
0.668 0.332 0.000
L54 Erythema in diseases classified elsewhere
0.667 0.333 0.000
Y52.1 Calcium-channel blockers
0.667 0.333 0.000
L51 Erythema multiforme
0.667 0.333 0.000
X50-X57 Overexertion, travel and privation
0.667 0.333 0.000
E11.4 With neurological complications
0.667 0.333 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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