TreeWAS – Variant ID: rs17540621

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M20.2 Hallux rigidus	0.044	0.956	0.000
R35 Polyuria	0.028	0.972	0.000
N18 Chronic renal failure	0.019	0.981	0.000
N18.3 Chronic kidney disease, stage 3	0.019	0.981	0.000
N18.5 Chronic kidney disease, stage 5	0.018	0.982	0.000
N18.9 Chronic renal failure, unspecified	0.017	0.983	0.000
N18.4 Chronic kidney disease, stage 4	0.016	0.984	0.000
N18.1 Chronic kidney disease, stage 1	0.016	0.984	0.000
N18.2 Chronic kidney disease, stage 2	0.016	0.984	0.000
N18.0 End-stage renal disease	0.015	0.985	0.000
N18.8 Other chronic renal failure	0.014	0.986	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.013	0.987	0.000
C18.9 Colon, unspecified	0.000	0.988	0.012
C18.7 Sigmoid colon	0.000	0.988	0.012
C18 Malignant neoplasm of colon	0.000	0.989	0.011
R01.1 Cardiac murmur, unspecified	0.000	0.989	0.011
M23.8 Other internal derangements of knee	0.010	0.990	0.000
C18.0 Caecum	0.000	0.990	0.010
C18.2 Ascending colon	0.000	0.990	0.010
C18.6 Descending colon	0.000	0.991	0.009
C18.5 Splenic flexure	0.000	0.991	0.009
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.009	0.991	0.000
H65-H75 Diseases of middle ear and mastoid	0.009	0.991	0.000
H71 Cholesteatoma of middle ear	0.009	0.991	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.009	0.991	0.000
C18.8 Overlapping lesion of colon	0.000	0.992	0.008
C18.1 Appendix	0.000	0.992	0.008
H66 Suppurative and unspecified otitis media	0.008	0.992	0.000
H74 Other disorders of middle ear and mastoid	0.008	0.992	0.000
H65 Nonsuppurative otitis media	0.008	0.992	0.000
H66.3 Other chronic suppurative otitis media	0.007	0.993	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.007	0.993	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.007	0.993	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.007	0.993	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.007	0.993	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.007	0.993	0.000
H73 Other disorders of tympanic membrane	0.007	0.993	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.007	0.993	0.000
N80.0 Endometriosis of uterus	0.007	0.993	0.000
C18.3 Hepatic flexure	0.000	0.993	0.007
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.007	0.993	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.007	0.993	0.000
H72 Perforation of tympanic membrane	0.007	0.993	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.006	0.993	0.000
H70 Mastoiditis and related conditions	0.006	0.993	0.000
H68 Eustachian salpingitis and obstruction	0.006	0.993	0.000
H67 Otitis media in diseases classified elsewhere	0.006	0.993	0.000
H65.2 Chronic serous otitis media	0.006	0.993	0.000
H66.9 Otitis media, unspecified	0.006	0.994	0.000
C18.4 Transverse colon	0.000	0.994	0.006
C19 Malignant neoplasm of rectosigmoid junction	0.000	0.994	0.006
H65.3 Chronic mucoid otitis media	0.006	0.994	0.000
H73.8 Other specified disorders of tympanic membrane	0.006	0.994	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.994	0.006
H66.4 Suppurative otitis media, unspecified	0.006	0.994	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.006	0.994	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.006	0.994	0.000
H66.0 Acute suppurative otitis media	0.006	0.994	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.006	0.994	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.006	0.994	0.000
H74.1 Adhesive middle ear disease	0.006	0.994	0.000
C15-C26 Malignant neoplasms of digestive organs	0.000	0.994	0.006
H72.8 Other perforations of tympanic membrane	0.006	0.994	0.000
H65.4 Other chronic nonsuppurative otitis media	0.006	0.994	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.006	0.994	0.000
H65.1 Other acute nonsuppurative otitis media	0.006	0.994	0.000
H65.0 Acute serous otitis media	0.006	0.994	0.000
H69 Other disorders of Eustachian tube	0.006	0.994	0.000
H74.0 Tympanosclerosis	0.006	0.994	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.005	0.995	0.000
H73.1 Chronic myringitis	0.005	0.995	0.000
H73.0 Acute myringitis	0.005	0.995	0.000
H74.4 Polyp of middle ear	0.005	0.995	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.995	0.005
H72.0 Central perforation of tympanic membrane	0.005	0.995	0.000
H72.2 Other marginal perforations of tympanic membrane	0.005	0.995	0.000
H72.1 Attic perforation of tympanic membrane	0.005	0.995	0.000
C20 Malignant neoplasm of rectum	0.000	0.995	0.005
H67.8 Otitis media in other diseases classified elsewhere	0.005	0.995	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.005	0.995	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.005	0.995	0.000
H68.1 Obstruction of Eustachian tube	0.005	0.995	0.000
H68.0 Eustachian salpingitis	0.005	0.995	0.000
H70.9 Mastoiditis, unspecified	0.005	0.995	0.000
H70.8 Other mastoiditis and related conditions	0.005	0.995	0.000
H70.2 Petrositis	0.005	0.995	0.000
H70.1 Chronic mastoiditis	0.005	0.995	0.000
H70.0 Acute mastoiditis	0.005	0.995	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.005	0.995	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.000	0.995	0.005
C26 Malignant neoplasm of other and ill-defined digestive organs	0.000	0.995	0.005
K91.3 Postoperative intestinal obstruction	0.000	0.995	0.005
S62.60 Fracture of other finger (closed)	0.005	0.995	0.000
C16 Malignant neoplasm of stomach	0.000	0.995	0.005
H93.1 Tinnitus	0.005	0.995	0.000
N80 Endometriosis	0.005	0.995	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.995	0.004
C23 Malignant neoplasm of gallbladder	0.000	0.995	0.004
H69.8 Other specified disorders of Eustachian tube	0.004	0.996	0.000
H69.0 Patulous Eustachian tube	0.004	0.996	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.996	0.004
C21 Malignant neoplasm of anus and anal canal	0.000	0.996	0.004
L57.0 Actinic keratosis	0.004	0.996	0.000
K91.4 Colostomy and enterostomy malfunction	0.000	0.996	0.004
H93 Other disorders of ear, not elsewhere classified	0.004	0.996	0.000
R01 Cardiac murmurs and other cardiac sounds	0.000	0.996	0.004
C26.0 Intestinal tract, part unspecified	0.000	0.996	0.004
N80.1 Endometriosis of ovary	0.004	0.996	0.000
C17 Malignant neoplasm of small intestine	0.000	0.996	0.004
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.000	0.996	0.004
H90.0 Conductive hearing loss, bilateral	0.004	0.996	0.000
H90-H95 Other disorders of ear	0.004	0.996	0.000
Chapter VIII Diseases of the ear and mastoid process	0.004	0.996	0.000
N80.2 Endometriosis of Fallopian tube	0.004	0.996	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.996	0.004
K91.5 Postcholecystectomy syndrome	0.000	0.996	0.004
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.996	0.004
K91.1 Postgastric surgery syndromes	0.000	0.996	0.004
M23 Internal derangement of knee	0.004	0.996	0.000
H90 Conductive and sensorineural hearing loss	0.004	0.996	0.000
C16.9 Stomach, unspecified	0.000	0.996	0.004
H72.9 Perforation of tympanic membrane, unspecified	0.004	0.996	0.000
C26.9 Ill-defined sites within the digestive system	0.000	0.996	0.004
C26.8 Overlapping lesion of digestive system	0.000	0.996	0.004
C26.1 Spleen	0.000	0.996	0.004
E87.2 Acidosis	0.000	0.996	0.004
N80.4 Endometriosis of rectovaginal septum and vagina	0.004	0.996	0.000
N80.8 Other endometriosis	0.004	0.996	0.000
H69.9 Eustachian tube disorder, unspecified	0.003	0.996	0.000
C16.8 Overlapping lesion of stomach	0.000	0.996	0.003
C16.6 Greater curvature of stomach, unspecified	0.000	0.996	0.003
C16.5 Lesser curvature of stomach, unspecified	0.000	0.996	0.003
C16.4 Pylorus	0.000	0.996	0.003
C16.3 Pyloric antrum	0.000	0.996	0.003
C16.2 Body of stomach	0.000	0.996	0.003
C16.1 Fundus of stomach	0.000	0.996	0.003
C21.1 Anal canal	0.000	0.996	0.003
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.004	0.996	0.000
N80.9 Endometriosis, unspecified	0.004	0.996	0.000
C22.7 Other specified carcinomas of liver	0.000	0.996	0.003
C22.4 Other sarcomas of liver	0.000	0.996	0.003
C22.3 Angiosarcoma of liver	0.000	0.996	0.003
C22.2 Hepatoblastoma	0.000	0.996	0.003
N80.6 Endometriosis in cutaneous scar	0.003	0.996	0.000
N80.5 Endometriosis of intestine	0.003	0.996	0.000
C22.9 Liver, unspecified	0.000	0.996	0.003
C22.0 Liver cell carcinoma	0.000	0.996	0.003
C22.1 Intrahepatic bile duct carcinoma	0.000	0.997	0.003
M23.6 Other spontaneous disruption of ligament(s) of knee	0.003	0.997	0.000
N17-N19 Renal failure	0.003	0.997	0.000
S62.6 Fracture of other finger	0.003	0.997	0.000
M23.4 Loose body in knee	0.003	0.997	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.997	0.003
C21.2 Cloacogenic zone	0.000	0.997	0.003
M20 Acquired deformities of fingers and toes	0.003	0.997	0.000
C16.0 Cardia	0.000	0.997	0.003
H93.9 Disorder of ear, unspecified	0.003	0.997	0.000
H93.8 Other specified disorders of ear	0.003	0.997	0.000
H93.3 Disorders of acoustic nerve	0.003	0.997	0.000
H93.2 Other abnormal auditory perceptions	0.003	0.997	0.000
H93.0 Degenerative and vascular disorders of ear	0.003	0.997	0.000
R01.2 Other cardiac sounds	0.000	0.997	0.003
M25.86 Other specified joint disorders (Lower leg)	0.003	0.997	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.003	0.997	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.997	0.003
C17.8 Overlapping lesion of small intestine	0.000	0.997	0.003
C17.3 Meckel's diverticulum	0.000	0.997	0.003
C17.1 Jejunum	0.000	0.997	0.003
C17.0 Duodenum	0.000	0.997	0.003
M23.1 Discoid meniscus (congenital)	0.003	0.997	0.000
C24.1 Ampulla of Vater	0.000	0.997	0.003
C24.9 Biliary tract, unspecified	0.000	0.997	0.003
C24.8 Overlapping lesion of biliary tract	0.000	0.997	0.003
M23.9 Internal derangement of knee, unspecified	0.003	0.997	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.003	0.997	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.003	0.997	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.003	0.997	0.000
C17.2 Ileum	0.000	0.997	0.003
R01.0 Benign and innocent cardiac murmurs	0.000	0.997	0.003
H92 Otalgia and effusion of ear	0.003	0.997	0.000
M23.49 Loose body in knee-Unspec lig/men	0.003	0.997	0.000
M23.0 Cystic meniscus	0.003	0.997	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.997	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.003	0.997	0.000
C21.0 Anus, unspecified	0.000	0.997	0.003
C17.9 Small intestine, unspecified	0.000	0.997	0.003
G63.2 Diabetic polyneuropathy	0.003	0.997	0.000
M23.5 Chronic instability of knee	0.003	0.997	0.000
Z47 Other orthopaedic follow-up care	0.000	0.997	0.003
H92.0 Otalgia	0.003	0.997	0.000
C24.0 Extrahepatic bile duct	0.000	0.997	0.003
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.997	0.000
H90.5 Sensorineural hearing loss, unspecified	0.003	0.997	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.003	0.997	0.000
S62.61 Fracture of other finger (open)	0.003	0.997	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.003	0.997	0.000
Z47.8 Other specified orthopaedic follow-up care	0.000	0.997	0.003
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.003	0.997	0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.003	0.997	0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.003	0.997	0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.003	0.997	0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.003	0.997	0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.003	0.997	0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.003	0.997	0.000
M23.47 Loose body in knee-Capsular lig	0.003	0.997	0.000
M23.46 Loose body in knee-O/unsp lat men	0.003	0.997	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.003	0.997	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.003	0.997	0.000
M23.43 Loose body in knee-Med lig/oth men	0.003	0.997	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.003	0.997	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.003	0.997	0.000
M23.40 Loose body in knee-Mult sites	0.003	0.997	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.003	0.997	0.000
H90.2 Conductive hearing loss, unspecified	0.003	0.997	0.000
C25 Malignant neoplasm of pancreas	0.000	0.997	0.002
H90.3 Sensorineural hearing loss, bilateral	0.003	0.997	0.000
M25.8 Other specified joint disorders	0.003	0.997	0.000
C15 Malignant neoplasm of oesophagus	0.000	0.997	0.003
S62.51 Fracture of thumb (open)	0.003	0.997	0.000
S62.5 Fracture of thumb	0.003	0.997	0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.002	0.997	0.000
M23.17 Discoid meniscus (congenital)-Capsular lig	0.002	0.997	0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.002	0.997	0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.997	0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.997	0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.997	0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.997	0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.002	0.997	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.003	0.997	0.000
H80-H83 Diseases of inner ear	0.003	0.997	0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.002	0.997	0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.002	0.997	0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.002	0.997	0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.997	0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.997	0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.997	0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.997	0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.002	0.997	0.000
R30.0 Dysuria	0.000	0.997	0.003
N70.1 Chronic salpingitis and oophoritis	0.003	0.997	0.000
S62.50 Fracture of thumb (closed)	0.003	0.997	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.002	0.997	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.002	0.997	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.002	0.997	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.002	0.997	0.000
H95.1 Other disorders following mastoidectomy	0.002	0.997	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.002	0.997	0.000
H60-H62 Diseases of external ear	0.003	0.997	0.000
M20.4 Other hammer toe(s) (acquired)	0.003	0.997	0.000
H92.2 Otorrhagia	0.002	0.997	0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.002	0.997	0.000
M23.07 Cystic meniscus-Capsular lig	0.002	0.997	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.002	0.997	0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.002	0.997	0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.997	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.997	0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.997	0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.997	0.000
M23.00 Cystic meniscus (Multiple sites)	0.002	0.997	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.002	0.997	0.000
N76.0 Acute vaginitis	0.002	0.997	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.002	0.998	0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.002	0.998	0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.002	0.998	0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
M23.50 Chronic instability of knee (Multiple sites)	0.002	0.998	0.000
L57.4 Cutis laxa senilis	0.002	0.998	0.000
Z47.9 Orthopaedic follow-up care, unspecified	0.000	0.998	0.002
S62 Fracture at wrist and hand level	0.002	0.998	0.000
M25.3 Other instability of joint	0.002	0.998	0.000
M25 Other joint disorders, not elsewhere classified	0.002	0.998	0.000
M25.37 Other instability of joint (Ankle and foot)	0.002	0.998	0.000
M20.0 Deformity of finger(s)	0.002	0.998	0.000
N70 Salpingitis and oophoritis	0.002	0.998	0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.002	0.998	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.002	0.998	0.000
L57.5 Actinic granuloma	0.002	0.998	0.000
L57.3 Poikiloderma of Civatte	0.002	0.998	0.000
L57.2 Cutis rhomboidalis nuchae	0.002	0.998	0.000
L57.1 Actinic reticuloid	0.002	0.998	0.000
N76 Other inflammation of vagina and vulva	0.002	0.998	0.000
C25.8 Overlapping lesion of pancreas	0.000	0.998	0.002
C25.7 Other parts of pancreas	0.000	0.998	0.002
C25.4 Endocrine pancreas	0.000	0.998	0.002
C25.3 Pancreatic duct	0.000	0.998	0.002
C25.2 Tail of pancreas	0.000	0.998	0.002
C25.1 Body of pancreas	0.000	0.998	0.002
N80.3 Endometriosis of pelvic peritoneum	0.002	0.998	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.002	0.998	0.000
M20.3 Other deformity of hallux (acquired)	0.002	0.998	0.000
S62.7 Multiple fractures of fingers	0.002	0.998	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.002	0.998	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.002	0.998	0.000
M25.88 Other specified joint disorders (Other)	0.002	0.998	0.000
M25.83 Other specified joint disorders (Forearm)	0.002	0.998	0.000
M25.82 Other specified joint disorders (Upper arm)	0.002	0.998	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.002	0.998	0.000
C15.8 Overlapping lesion of oesophagus	0.000	0.998	0.002
C15.3 Upper third of oesophagus	0.000	0.998	0.002
C15.2 Abdominal part of oesophagus	0.000	0.998	0.002
C15.1 Thoracic part of oesophagus	0.000	0.998	0.002
C15.0 Cervical part of oesophagus	0.000	0.998	0.002
S62.71 Multiple fractures of fingers (open)	0.002	0.998	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.002	0.998	0.000
M20-M25 Other joint disorders	0.002	0.998	0.000
N76.2 Acute vulvitis	0.002	0.998	0.000
H83 Other diseases of inner ear	0.002	0.998	0.000
M25.34 Other instability of joint (Hand)	0.002	0.998	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.002	0.998	0.000
M25.0 Haemarthrosis	0.002	0.998	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.002	0.998	0.000
O36.8 Maternal care for other specified foetal problems	0.002	0.998	0.000
H91 Other hearing loss	0.002	0.998	0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.002	0.998	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.002	0.998	0.000
M25.9 Joint disorder, unspecified	0.002	0.998	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.002	0.998	0.000
N70.9 Salpingitis and oophoritis, unspecified	0.002	0.998	0.000
N76.3 Subacute and chronic vulvitis	0.002	0.998	0.000
N72 Inflammatory disease of cervix uteri	0.002	0.998	0.000
M25.06 Haemarthrosis (Lower leg)	0.002	0.998	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M23.3 Other meniscus derangements	0.002	0.998	0.000
N75.1 Abscess of Bartholin's gland	0.002	0.998	0.000
T43.2 Other and unspecified antidepressants	0.000	0.998	0.002
H60 Otitis externa	0.002	0.998	0.000
S62.4 Multiple fractures of metacarpal bones	0.002	0.998	0.000
C15.4 Middle third of oesophagus	0.000	0.998	0.002
M25.39 Other instability of joint (Site unspecified)	0.002	0.998	0.000
M25.38 Other instability of joint (Other)	0.002	0.998	0.000
M25.36 Other instability of joint (Lower leg)	0.002	0.998	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.002	0.998	0.000
M25.33 Other instability of joint (Forearm)	0.002	0.998	0.000
M25.32 Other instability of joint (Upper arm)	0.002	0.998	0.000
M25.30 Other instability of joint (Multiple sites)	0.002	0.998	0.000
S62.1 Fracture of other carpal bone(s)	0.002	0.998	0.000
M25.2 Flail joint	0.002	0.998	0.000
M25.1 Fistula of joint	0.002	0.998	0.000
N70.0 Acute salpingitis and oophoritis	0.002	0.998	0.000
H81 Disorders of vestibular function	0.002	0.998	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.002	0.998	0.000
N76.6 Ulceration of vulva	0.002	0.998	0.000
N76.5 Ulceration of vagina	0.002	0.998	0.000
N76.1 Subacute and chronic vaginitis	0.002	0.998	0.000
E10.5 With peripheral circulatory complications	0.002	0.998	0.000
J34.3 Hypertrophy of nasal turbinates	0.002	0.998	0.000
H80 Otosclerosis	0.001	0.998	0.001
N76.8 Other specified inflammation of vagina and vulva	0.002	0.998	0.000
M33 Dermatopolymyositis	0.002	0.998	0.000
S62.70 Multiple fractures of fingers (closed)	0.002	0.998	0.000
M25.31 Other instability of joint (Shoulder region)	0.002	0.998	0.000
M25.71 Osteophyte (Shoulder region)	0.002	0.998	0.000
H92.1 Otorrhoea	0.002	0.998	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.998	0.002
M30 Polyarteritis nodosa and related conditions	0.002	0.998	0.000
H60.5 Acute otitis externa, non-infective	0.002	0.998	0.000
H81.2 Vestibular neuronitis	0.002	0.998	0.000
H83.9 Disease of inner ear, unspecified	0.002	0.998	0.000
H83.8 Other specified diseases of inner ear	0.002	0.998	0.000
H83.3 Noise effects on inner ear	0.002	0.998	0.000
H83.2 Labyrinthine dysfunction	0.002	0.998	0.000
H83.1 Labyrinthine fistula	0.002	0.998	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.998	0.002
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.002	0.998	0.000
M32 Systemic lupus erythematosus	0.002	0.998	0.000
M25.09 Haemarthrosis (Site unspecified)	0.002	0.998	0.000
M25.08 Haemarthrosis (Other)	0.002	0.998	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.002	0.998	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.002	0.998	0.000
M25.04 Haemarthrosis (Hand)	0.002	0.998	0.000
M25.03 Haemarthrosis (Forearm)	0.002	0.998	0.000
M25.02 Haemarthrosis (Upper arm)	0.002	0.998	0.000
M25.01 Haemarthrosis (Shoulder region)	0.002	0.998	0.000
M25.00 Haemarthrosis (Multiple sites)	0.002	0.998	0.000
M25.84 Other specified joint disorders (Hand)	0.002	0.998	0.000
M25.4 Effusion of joint	0.002	0.998	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
M25.97 Joint disorder, unspecified (Ankle and foot)	0.002	0.998	0.000
H60.8 Other otitis externa	0.002	0.998	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.002	0.998	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.002	0.998	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H62.2 Otitis externa in mycoses	0.002	0.998	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.002	0.998	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.002	0.998	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.002	0.998	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.002	0.998	0.000
H83.0 Labyrinthitis	0.002	0.998	0.000
R60.0 Localised oedema	0.000	0.998	0.002
N75 Diseases of Bartholin's gland	0.002	0.998	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.002	0.998	0.000
H91.8 Other specified hearing loss	0.001	0.998	0.000
H91.3 Deaf mutism, not elsewhere classified	0.001	0.998	0.000
H91.2 Sudden idiopathic hearing loss	0.001	0.998	0.000
H91.1 Presbycusis	0.001	0.998	0.000
H91.0 Ototoxic hearing loss	0.001	0.998	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.002	0.998	0.000
N19 Unspecified renal failure	0.002	0.998	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.001	0.998	0.000
S62.2 Fracture of first metacarpal bone	0.002	0.998	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.002	0.998	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.002	0.998	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.002	0.998	0.000
M25.98 Joint disorder, unspecified (Other)	0.002	0.998	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M25.94 Joint disorder, unspecified (Hand)	0.002	0.998	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.002	0.998	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.002	0.998	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.002	0.998	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.002	0.998	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.002	0.998	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.998	0.002
M34 Systemic sclerosis	0.002	0.998	0.000
M23.37 Other meniscus derangements-Capsular lig	0.002	0.998	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
C15.5 Lower third of oesophagus	0.000	0.998	0.002
H60.4 Cholesteatoma of external ear	0.002	0.998	0.000
H60.3 Other infective otitis externa	0.002	0.998	0.000
H60.2 Malignant otitis externa	0.002	0.998	0.000
H60.0 Abscess of external ear	0.002	0.998	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.001	0.998	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.002	0.998	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.001	0.998	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.001	0.998	0.000
S62.3 Fracture of other metacarpal bone	0.002	0.998	0.000
M24 Other specific joint derangements	0.002	0.998	0.000
M25.19 Fistula of joint (Site unspecified)	0.001	0.998	0.000
M25.18 Fistula of joint (Other)	0.001	0.998	0.000
M25.17 Fistula of joint (Ankle and foot)	0.001	0.998	0.000
M25.16 Fistula of joint (Lower leg)	0.001	0.998	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.001	0.998	0.000
M25.14 Fistula of joint (Hand)	0.001	0.998	0.000
M25.13 Fistula of joint (Forearm)	0.001	0.998	0.000
M25.12 Fistula of joint (Upper arm)	0.001	0.998	0.000
M25.11 Fistula of joint (Shoulder region)	0.001	0.998	0.000
M25.10 Fistula of joint (Multiple sites)	0.001	0.998	0.000
M25.29 Flail joint (Site unspecified)	0.001	0.998	0.000
M25.28 Flail joint (Other)	0.001	0.998	0.000
M25.27 Flail joint (Ankle and foot)	0.001	0.998	0.000
M25.26 Flail joint (Lower leg)	0.001	0.998	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.001	0.998	0.000
M25.24 Flail joint (Hand)	0.001	0.998	0.000
M25.23 Flail joint (Forearm)	0.001	0.998	0.000
M25.22 Flail joint (Upper arm)	0.001	0.998	0.000
M25.21 Flail joint (Shoulder region)	0.001	0.998	0.000
M25.20 Flail joint (Multiple sites)	0.001	0.998	0.000
H81.9 Disorder of vestibular function, unspecified	0.001	0.998	0.000
H81.8 Other disorders of vestibular function	0.001	0.998	0.000
H81.4 Vertigo of central origin	0.001	0.998	0.000
H81.3 Other peripheral vertigo	0.001	0.998	0.000
M33.2 Polymyositis	0.001	0.998	0.000
N76.4 Abscess of vulva	0.002	0.998	0.000
N17 Acute renal failure	0.002	0.998	0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.002	0.998	0.000
K90-K93 Other diseases of the digestive system	0.000	0.998	0.002
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.002	0.998	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.002	0.998	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.002	0.998	0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.002	0.998	0.000
K90 Intestinal malabsorption	0.000	0.998	0.002
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.002	0.998	0.000
C25.9 Pancreas, unspecified	0.000	0.998	0.001
C25.0 Head of pancreas	0.001	0.998	0.001
H80.8 Other otosclerosis	0.001	0.998	0.001
H80.2 Cochlear otosclerosis	0.001	0.998	0.001
H80.1 Otosclerosis involving oval window, obliterative	0.001	0.998	0.001
H80.0 Otosclerosis involving oval window, nonobliterative	0.001	0.998	0.001
C50.4 Upper-outer quadrant of breast	0.002	0.998	0.000
M33.9 Dermatopolymyositis, unspecified	0.001	0.998	0.000
M33.1 Other dermatomyositis	0.001	0.998	0.000
M33.0 Juvenile dermatomyositis	0.001	0.998	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.998	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.001	0.998	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.001	0.998	0.000
M30.2 Juvenile polyarteritis	0.001	0.998	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.001	0.998	0.000
M30.0 Polyarteritis nodosa	0.001	0.998	0.000
M25.49 Effusion of joint (Site unspecified)	0.001	0.998	0.000
M25.48 Effusion of joint (Other)	0.001	0.998	0.000
M25.44 Effusion of joint (Hand)	0.001	0.998	0.000
M25.43 Effusion of joint (Forearm)	0.001	0.998	0.000
M25.42 Effusion of joint (Upper arm)	0.001	0.998	0.000
M25.41 Effusion of joint (Shoulder region)	0.001	0.998	0.000
M25.40 Effusion of joint (Multiple sites)	0.001	0.998	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.001	0.998	0.000
M32.8 Other forms of systemic lupus erythematosus	0.001	0.998	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.001	0.998	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.001	0.998	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.001	0.998	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations