TreeWAS – Variant ID: rs17541203

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S82.60 Fracture of lateral malleolus (closed)	0.017	0.983	0.000
S82.6 Fracture of lateral malleolus	0.012	0.988	0.000
S82.61 Fracture of lateral malleolus (open)	0.009	0.991	0.000
S82 Fracture of lower leg, including ankle	0.009	0.991	0.000
S82.0 Fracture of patella	0.008	0.992	0.000
S82.4 Fracture of fibula alone	0.008	0.992	0.000
S82.00 Fracture of patella (closed)	0.008	0.992	0.000
E66.8 Other obesity	0.000	0.993	0.007
S82.3 Fracture of lower end of tibia	0.007	0.993	0.000
S82.8 Fractures of other parts of lower leg	0.007	0.993	0.000
S82.40 Fracture of fibula alone (closed)	0.007	0.993	0.000
S82.01 Fracture of patella (open)	0.007	0.993	0.000
S82.9 Fracture of lower leg, part unspecified	0.007	0.993	0.000
S82.7 Multiple fractures of lower leg	0.007	0.993	0.000
M43.16 Spondylolisthesis (Lumbar region)	0.007	0.993	0.000
S82.5 Fracture of medial malleolus	0.007	0.993	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.007	0.993	0.000
E66.9 Obesity, unspecified	0.000	0.994	0.006
S82.80 Fractures of other parts of lower leg (closed)	0.006	0.994	0.000
E66 Obesity	0.000	0.994	0.006
S82.1 Fracture of upper end of tibia	0.006	0.994	0.000
S82.41 Fracture of fibula alone (open)	0.006	0.994	0.000
K11.2 Sialoadenitis	0.000	0.994	0.006
S82.31 Fracture of lower end of tibia (open)	0.006	0.994	0.000
S82.30 Fracture of lower end of tibia (closed)	0.005	0.994	0.000
M43.1 Spondylolisthesis	0.005	0.995	0.000
S82.86 Maisonneuve's fracture	0.005	0.995	0.000
S82.2 Fracture of shaft of tibia	0.005	0.995	0.000
M43.12 Spondylolisthesis (Cervical region)	0.005	0.995	0.000
Z03.4 Observation for suspected myocardial infarction	0.005	0.995	0.000
S82.71 Multiple fractures of lower leg (open)	0.005	0.995	0.000
S82.70 Multiple fractures of lower leg (closed)	0.005	0.995	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.005	0.995	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.005	0.995	0.000
S82.51 Fracture of medial malleolus (open)	0.005	0.995	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
S82.50 Fracture of medial malleolus (closed)	0.005	0.995	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.995	0.004
E66.1 Drug-induced obesity	0.000	0.995	0.004
N35.9 Urethral stricture, unspecified	0.005	0.995	0.000
S82.11 Fracture of upper end of tibia (open)	0.004	0.995	0.000
S82.81 Fractures of other parts of lower leg (open)	0.004	0.995	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.004	0.996	0.000
E66.0 Obesity due to excess calories	0.000	0.996	0.004
M43.19 Spondylolisthesis (Site unspecified)	0.004	0.996	0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.004	0.996	0.000
M43.15 Spondylolisthesis (Thoracolumbar region)	0.004	0.996	0.000
M43.14 Spondylolisthesis (Thoracic region)	0.004	0.996	0.000
M43.13 Spondylolisthesis (Cervicothoracic region)	0.004	0.996	0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.004	0.996	0.000
M43.10 Spondylolisthesis (Multiple sites in spine)	0.004	0.996	0.000
S82.21 Fracture of shaft of tibia (open)	0.004	0.996	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
M43.17 Spondylolisthesis (Lumbosacral region)	0.004	0.996	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.000	0.996	0.004
S82.10 Fracture of upper end of tibia (closed)	0.004	0.996	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
I63.9 Cerebral infarction, unspecified	0.004	0.996	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
K11 Diseases of salivary glands	0.000	0.997	0.003
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.003	0.997	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
M43 Other deforming dorsopathies	0.003	0.997	0.000
I69.3 Sequelae of cerebral infarction	0.003	0.997	0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.000	0.997	0.003
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.003	0.997	0.000
K11.6 Mucocele of salivary gland	0.000	0.997	0.003
K11.9 Disease of salivary gland, unspecified	0.000	0.997	0.003
S80-S89 Injuries to the knee and lower leg	0.003	0.997	0.000
D47.1 Chronic myeloproliferative disease	0.003	0.997	0.000
M06.9 Rheumatoid arthritis, unspecified	0.003	0.997	0.000
S89.9 Unspecified injury of lower leg	0.003	0.997	0.000
I63 Cerebral infarction	0.003	0.997	0.000
S89 Other and unspecified injuries of lower leg	0.003	0.997	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.003	0.997	0.000
I63.8 Other cerebral infarction	0.003	0.997	0.000
M43.6 Torticollis	0.003	0.997	0.000
S86 Injury of muscle and tendon at lower leg level	0.003	0.997	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.003	0.997	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.003	0.997	0.000
E65-E68 Obesity and other hyperalimentation	0.000	0.997	0.003
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.003	0.997	0.000
K11.7 Disturbances of salivary secretion	0.000	0.997	0.002
K11.4 Fistula of salivary gland	0.000	0.997	0.002
K11.3 Abscess of salivary gland	0.000	0.997	0.002
K11.0 Atrophy of salivary gland	0.000	0.997	0.002
D44.3 Pituitary gland	0.003	0.997	0.000
H54.0 Blindness, both eyes	0.000	0.997	0.003
M43.9 Deforming dorsopathy, unspecified	0.002	0.997	0.000
M43.8 Other specified deforming dorsopathies	0.002	0.997	0.000
M43.5 Other recurrent vertebral subluxation	0.002	0.997	0.000
M43.4 Other recurrent atlantoaxial subluxation	0.002	0.997	0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.002	0.997	0.000
M43.2 Other fusion of spine	0.002	0.997	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.002	0.997	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.003	0.997	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.003	0.997	0.000
D47.4 Osteomyelofibrosis	0.002	0.997	0.000
S82.20 Fracture of shaft of tibia (closed)	0.002	0.997	0.000
A04.5 Campylobacter enteritis	0.003	0.997	0.000
K11.8 Other diseases of salivary glands	0.000	0.997	0.002
M06.0 Seronegative rheumatoid arthritis	0.002	0.997	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.002	0.998	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.002	0.998	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.002	0.998	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.002	0.998	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.002	0.998	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.002	0.998	0.000
M43.0 Spondylolysis	0.002	0.998	0.000
K11.1 Hypertrophy of salivary gland	0.000	0.998	0.002
M43.62 Torticollis-Cervical	0.002	0.998	0.000
K11.5 Sialolithiasis	0.000	0.998	0.002
I69 Sequelae of cerebrovascular disease	0.002	0.998	0.000
C90.0 Multiple myeloma	0.002	0.998	0.000
S88 Traumatic amputation of lower leg	0.002	0.998	0.000
S87 Crushing injury of lower leg	0.002	0.998	0.000
S85 Injury of blood vessels at lower leg level	0.002	0.998	0.000
S84 Injury of nerves at lower leg level	0.002	0.998	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.002	0.998	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.002	0.998	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.002	0.998	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.002	0.998	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.002	0.998	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.002	0.998	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.002	0.998	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.998	0.002
S89.8 Other specified injuries of lower leg	0.002	0.998	0.000
S89.7 Multiple injuries of lower leg	0.002	0.998	0.000
S89.1 Other specified injuries of lower leg	0.002	0.998	0.000
S89.0 Multiple injuries of lower leg	0.002	0.998	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.002	0.998	0.000
M06 Other rheumatoid arthritis	0.002	0.998	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.002	0.998	0.000
D46 Myelodysplastic syndromes	0.002	0.998	0.000
D45 Polycythaemia vera	0.002	0.998	0.000
M43.69 Torticollis-Site unspe	0.002	0.998	0.000
M43.68 Torticollis-Sacral/sacrococ	0.002	0.998	0.000
M43.67 Torticollis-Lumbosacral	0.002	0.998	0.000
M43.66 Torticollis-Lumbar	0.002	0.998	0.000
M43.65 Torticollis-Thoracolumbar	0.002	0.998	0.000
M43.64 Torticollis-Thoracic	0.002	0.998	0.000
M43.63 Torticollis-Cervicothoracic	0.002	0.998	0.000
M43.61 Torticollis-Occipit-atl-axl	0.002	0.998	0.000
M43.60 Torticollis-Mult site	0.002	0.998	0.000
S86.0 Injury of Achilles tendon	0.002	0.998	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.002	0.998	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.002	0.998	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.002	0.998	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.002	0.998	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.002	0.998	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.002	0.998	0.000
E67 Other hyperalimentation	0.000	0.998	0.002
E68 Sequelae of hyperalimentation	0.000	0.998	0.002
E65 Localised adiposity	0.000	0.998	0.002
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
S80 Superficial injury of lower leg	0.002	0.998	0.000
M43.29 Other fusion of spine (Site unspecified)	0.002	0.998	0.000
M43.28 Other fusion of spine (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M43.27 Other fusion of spine (Lumbosacral region)	0.002	0.998	0.000
M43.26 Other fusion of spine (Lumbar region)	0.002	0.998	0.000
M43.25 Other fusion of spine (Thoracolumbar region)	0.002	0.998	0.000
M43.24 Other fusion of spine (Thoracic region)	0.002	0.998	0.000
M43.23 Other fusion of spine (Cervicothoracic region)	0.002	0.998	0.000
M43.22 Other fusion of spine (Cervical region)	0.002	0.998	0.000
M43.21 Other fusion of spine (Occipito-atlanto-axial region)	0.002	0.998	0.000
M43.20 Other fusion of spine (Multiple sites in spine)	0.002	0.998	0.000
M43.39 Recurrent atlantoaxial subluxation with myelopathy (Site unspecified)	0.002	0.998	0.000
M43.38 Recurrent atlantoaxial subluxation with myelopathy (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M43.37 Recurrent atlantoaxial subluxation with myelopathy (Lumbosacral region)	0.002	0.998	0.000
M43.36 Recurrent atlantoaxial subluxation with myelopathy (Lumbar region)	0.002	0.998	0.000
M43.35 Recurrent atlantoaxial subluxation with myelopathy (Thoracolumbar region)	0.002	0.998	0.000
M43.34 Recurrent atlantoaxial subluxation with myelopathy (Thoracic region)	0.002	0.998	0.000
M43.33 Recurrent atlantoaxial subluxation with myelopathy (Cervicothoracic region)	0.002	0.998	0.000
M43.32 Recurrent atlantoaxial subluxation with myelopathy (Cervical region)	0.002	0.998	0.000
M43.31 Recurrent atlantoaxial subluxation with myelopathy (Occipito-atlanto-axial region)	0.002	0.998	0.000
M43.30 Recurrent atlantoaxial subluxation with myelopathy (Multiple sites in spine)	0.002	0.998	0.000
M43.49 Other recurrent atlantoaxial subluxation-Site unspe	0.002	0.998	0.000
M43.48 Other recurrent atlantoaxial subluxation-Sacral/sacrococ	0.002	0.998	0.000
M43.47 Other recurrent atlantoaxial subluxation-Lumbosacral	0.002	0.998	0.000
M43.46 Other recurrent atlantoaxial subluxation-Lumbar	0.002	0.998	0.000
M43.45 Other recurrent atlantoaxial subluxation-Thoracolumbar	0.002	0.998	0.000
M43.44 Other recurrent atlantoaxial subluxation-Thoracic	0.002	0.998	0.000
M43.43 Other recurrent atlantoaxial subluxation-Cervicothoracic	0.002	0.998	0.000
M43.42 Other recurrent atlantoaxial subluxation-Cervical	0.002	0.998	0.000
M43.41 Other recurrent atlantoaxial subluxation-Occipit-atl-axl	0.002	0.998	0.000
M43.40 Other recurrent atlantoaxial subluxation-Mult site	0.002	0.998	0.000
M43.59 Other recurrent vertebral subluxation (Site unspecified)	0.002	0.998	0.000
M43.58 Other recurrent vertebral subluxation (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M43.57 Other recurrent vertebral subluxation (Lumbosacral region)	0.002	0.998	0.000
M43.56 Other recurrent vertebral subluxation (Lumbar region)	0.002	0.998	0.000
M43.55 Other recurrent vertebral subluxation (Thoracolumbar region)	0.002	0.998	0.000
M43.54 Other recurrent vertebral subluxation (Thoracic region)	0.002	0.998	0.000
M43.53 Other recurrent vertebral subluxation (Cervicothoracic region)	0.002	0.998	0.000
M43.52 Other recurrent vertebral subluxation (Cervical region)	0.002	0.998	0.000
M43.51 Other recurrent vertebral subluxation-Occipit-atl-axl	0.002	0.998	0.000
M43.50 Other recurrent vertebral subluxation (Multiple sites in spine)	0.002	0.998	0.000
M43.89 Other specified deforming dorsopathies (Site unspecified)	0.002	0.998	0.000
M43.88 Other specified deforming dorsopathies (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M43.87 Other specified deforming dorsopathies (Lumbosacral region)	0.002	0.998	0.000
M43.86 Other specified deforming dorsopathies (Lumbar region)	0.002	0.998	0.000
M43.85 Other specified deforming dorsopathies (Thoracolumbar region)	0.002	0.998	0.000
M43.84 Other specified deforming dorsopathies (Thoracic region)	0.002	0.998	0.000
M43.83 Other specified deforming dorsopathies (Cervicothoracic region)	0.002	0.998	0.000
M43.82 Other specified deforming dorsopathies (Cervical region)	0.002	0.998	0.000
M43.81 Other specified deforming dorsopathies (Occipito-atlanto-axial region)	0.002	0.998	0.000
M43.80 Other specified deforming dorsopathies (Multiple sites in spine)	0.002	0.998	0.000
M43.99 Deforming dorsopathy, unspecified (Site unspecified)	0.002	0.998	0.000
M43.98 Deforming dorsopathy, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M43.97 Deforming dorsopathy, unspecified (Lumbosacral region)	0.002	0.998	0.000
M43.96 Deforming dorsopathy, unspecified (Lumbar region)	0.002	0.998	0.000
M43.95 Deforming dorsopathy, unspecified (Thoracolumbar region)	0.002	0.998	0.000
M43.94 Deforming dorsopathy, unspecified (Thoracic region)	0.002	0.998	0.000
M43.93 Deforming dorsopathy, unspecified (Cervicothoracic region)	0.002	0.998	0.000
M43.92 Deforming dorsopathy, unspecified (Cervical region)	0.002	0.998	0.000
M43.91 Deforming dorsopathy, unspecified (Occipito-atlanto-axial region)	0.002	0.998	0.000
M43.90 Deforming dorsopathy, unspecified (Multiple sites in spine)	0.002	0.998	0.000
Z83.5 Family history of eye and ear disorders	0.002	0.998	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.002	0.998	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.002	0.998	0.000
M43.06 Spondylolysis (Lumbar region)	0.002	0.998	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.002	0.998	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.002	0.998	0.000
E55.9 Vitamin D deficiency, unspecified	0.000	0.998	0.002
M06.08 Seronegative rheumatoid arthritis (Other)	0.002	0.998	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.002	0.998	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.002	0.998	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.002	0.998	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.002	0.998	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.002	0.998	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.002	0.998	0.000
M54.49 Lumbago with sciatica (Site unspecified)	0.002	0.998	0.000
M07.3 Other psoriatic arthropathies	0.002	0.998	0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.002	0.998	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.002	0.998	0.000
D44.9 Endocrine gland, unspecified	0.002	0.998	0.000
D44.8 Pluriglandular involvement	0.002	0.998	0.000
D44.7 Aortic body and other paraganglia	0.002	0.998	0.000
D44.6 Carotid body	0.002	0.998	0.000
D44.5 Pineal gland	0.002	0.998	0.000
D44.4 Craniopharyngeal duct	0.002	0.998	0.000
D44.2 Parathyroid gland	0.002	0.998	0.000
D44.1 Adrenal gland	0.002	0.998	0.000
D44.0 Thyroid gland	0.002	0.998	0.000
G43.9 Migraine, unspecified	0.000	0.998	0.002
S80.0 Contusion of knee	0.002	0.998	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.002	0.998	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
M43.09 Spondylolysis (Site unspecified)	0.002	0.998	0.000
M43.08 Spondylolysis (Sacral and sacrococcygeal region)	0.002	0.998	0.000
M43.07 Spondylolysis (Lumbosacral region)	0.002	0.998	0.000
M43.05 Spondylolysis (Thoracolumbar region)	0.002	0.998	0.000
M43.04 Spondylolysis (Thoracic region)	0.002	0.998	0.000
M43.03 Spondylolysis (Cervicothoracic region)	0.002	0.998	0.000
M43.01 Spondylolysis (Occipito-atlanto-axial region)	0.002	0.998	0.000
M43.00 Spondylolysis (Multiple sites in spine)	0.002	0.998	0.000
C54.1 Endometrium	0.002	0.998	0.000
D39.1 Ovary	0.002	0.998	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.002	0.998	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.002	0.998	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.002	0.998	0.000
D48.7 Other specified sites	0.002	0.998	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.002	0.998	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.002	0.998	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.002	0.998	0.000
S84.8 Injury of other nerves at lower leg level	0.002	0.998	0.000
S84.7 Injury of multiple nerves at lower leg level	0.002	0.998	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.002	0.998	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.002	0.998	0.000
S84.0 Injury of tibial nerve at lower leg level	0.002	0.998	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.002	0.998	0.000
S85.8 Injury of other blood vessels at lower leg level	0.002	0.998	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.002	0.998	0.000
S85.5 Injury of popliteal vein	0.002	0.998	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.002	0.998	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.002	0.998	0.000
S85.2 Injury of peroneal artery	0.002	0.998	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.002	0.998	0.000
S85.0 Injury of popliteal artery	0.002	0.998	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.002	0.998	0.000
S87.0 Crushing injury of knee	0.002	0.998	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.002	0.998	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.002	0.998	0.000
S88.0 Traumatic amputation at knee level	0.002	0.998	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.002	0.998	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.002	0.998	0.000
Z35.8 Supervision of other high-risk pregnancies	0.002	0.998	0.000
Z40 Prophylactic surgery	0.000	0.998	0.002
H57.1 Ocular pain	0.000	0.998	0.002
M06.8 Other specified rheumatoid arthritis	0.002	0.998	0.000
M06.4 Inflammatory polyarthropathy	0.002	0.998	0.000
M06.2 Rheumatoid bursitis	0.002	0.998	0.000
M06.1 Adult-onset Still's disease	0.002	0.998	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.002	0.998	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.002	0.998	0.000
D46.7 Other myelodysplastic syndromes	0.002	0.998	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.002	0.998	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.002	0.998	0.000
D46.4 Refractory anaemia, unspecified	0.002	0.998	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.002	0.998	0.000
D46.2 Refractory anaemia with excess of blasts	0.002	0.998	0.000
D46.1 Refractory anaemia with sideroblasts	0.002	0.998	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.002	0.998	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.000	0.998	0.002
Q23.1 Congenital insufficiency of aortic valve	0.002	0.998	0.000
J92.9 Pleural plaque without asbestos	0.000	0.998	0.002
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.002	0.998	0.000
D48.1 Connective and other soft tissue	0.002	0.998	0.000
Z03.8 Observation for other suspected diseases and conditions	0.000	0.998	0.002
S86.00 Unspecified injury of Achilles tendon	0.002	0.998	0.000
D40.1 Testis	0.002	0.998	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.002	0.998	0.000
C90.2 Plasmacytoma, extramedullary	0.002	0.998	0.000
E67.8 Other specified hyperalimentation	0.000	0.998	0.002
E67.3 Hypervitaminosis D	0.000	0.998	0.002
E67.2 Megavitamin-B6 syndrome	0.000	0.998	0.002
E67.1 Hypercarotenaemia	0.000	0.998	0.002
E67.0 Hypervitaminosis A	0.000	0.998	0.002
Z36 Antenatal screening	0.002	0.998	0.000
C82.0 Small cleaved cell, follicular	0.002	0.998	0.000
D48.0 Bone and articular cartilage	0.002	0.998	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.002	0.998	0.000
N35 Urethral stricture	0.002	0.998	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.002	0.998	0.000
D39.9 Female genital organ, unspecified	0.002	0.998	0.000
D39.7 Other female genital organs	0.002	0.998	0.000
D39.2 Placenta	0.002	0.998	0.000
D39.0 Uterus	0.002	0.998	0.000
D40.0 Prostate	0.002	0.998	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.002	0.998	0.000
D48.4 Peritoneum	0.002	0.998	0.000
D48.3 Retroperitoneum	0.002	0.998	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.002	0.998	0.000
S80.7 Multiple superficial injuries of lower leg	0.002	0.998	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.002	0.998	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.002	0.998	0.000
D48.5 Skin	0.002	0.998	0.000
Z40.8 Other prophylactic surgery	0.000	0.998	0.002
G62.9 Polyneuropathy, unspecified	0.000	0.998	0.002
H54.4 Blindness, one eye	0.000	0.998	0.002
N80.1 Endometriosis of ovary	0.002	0.998	0.000
M07.38 Other psoriatic arthropathies (Other)	0.002	0.998	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.002	0.998	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.002	0.998	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.002	0.998	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.002	0.998	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.002	0.998	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.002	0.998	0.000
D40.9 Male genital organ, unspecified	0.002	0.998	0.000
D40.7 Other male genital organs	0.002	0.998	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.002	0.998	0.000
M06.3 Rheumatoid nodule	0.002	0.998	0.000
Z50.5 Speech therapy	0.002	0.998	0.000
D38.1 Trachea, bronchus and lung	0.002	0.998	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.002	0.998	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.002	0.998	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.002	0.998	0.000
C90.3 Solitary plasmacytoma	0.002	0.998	0.000
C90.1 Plasma cell leukaemia	0.002	0.998	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.002	0.998	0.000
D38.6 Respiratory organ, unspecified	0.001	0.998	0.000
D38.5 Other respiratory organs	0.001	0.998	0.000
D38.4 Thymus	0.001	0.998	0.000
D38.3 Mediastinum	0.001	0.998	0.000
D38.2 Pleura	0.001	0.998	0.000
D38.0 Larynx	0.001	0.998	0.000
H43.1 Vitreous haemorrhage	0.002	0.998	0.000
S50.9 Superficial injury of forearm, unspecified	0.002	0.998	0.000
S80.9 Superficial injury of lower leg, unspecified	0.002	0.998	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.002	0.998	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.002	0.998	0.000
M43.02 Spondylolysis (Cervical region)	0.001	0.998	0.000
H54.9 Unspecified visual impairment (binocular)	0.000	0.998	0.002
Z40.9 Prophylactic surgery, unspecified	0.000	0.998	0.002
A04 Other bacterial intestinal infections	0.002	0.998	0.000
C88 Malignant immunoproliferative diseases	0.002	0.998	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.001	0.998	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.001	0.998	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.001	0.998	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.001	0.998	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.001	0.998	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.001	0.998	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.001	0.998	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.001	0.998	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.001	0.998	0.000
C93.1 Chronic monocytic leukaemia	0.002	0.998	0.000
D42.9 Meninges, unspecified	0.001	0.998	0.000
D42.1 Spinal meninges	0.001	0.998	0.000
D42.0 Cerebral meninges	0.001	0.998	0.000
M20.4 Other hammer toe(s) (acquired)	0.002	0.998	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.002	0.998	0.000
C54 Malignant neoplasm of corpus uteri	0.002	0.998	0.000
Z83 Family history of other specific disorders	0.002	0.998	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.001	0.998	0.000
M06.18 Adult-onset Still's disease (Other)	0.001	0.998	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.001	0.998	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.001	0.998	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.001	0.998	0.000
M06.14 Adult-onset Still's disease (Hand)	0.001	0.998	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.001	0.998	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.001	0.998	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.001	0.998	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.001	0.998	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.001	0.998	0.000
M06.28 Rheumatoid bursitis (Other)	0.001	0.998	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.001	0.998	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.001	0.998	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.001	0.998	0.000
M06.24 Rheumatoid bursitis (Hand)	0.001	0.998	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.001	0.998	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.001	0.998	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.001	0.998	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.001	0.998	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.001	0.998	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.001	0.998	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.001	0.998	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.001	0.998	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.001	0.998	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.001	0.998	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.001	0.998	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.001	0.998	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.001	0.998	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.001	0.998	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.001	0.998	0.000
K04.7 Periapical abscess without sinus	0.000	0.998	0.002
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.002	0.998	0.000
D37.5 Rectum	0.002	0.998	0.000
D47.2 Monoclonal gammopathy	0.001	0.998	0.000
M31.6 Other giant cell arteritis	0.002	0.998	0.000
U80.1 Methicillin resistant agent	0.000	0.998	0.002
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.002	0.998	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.002	0.998	0.000
A04.9 Bacterial intestinal infection, unspecified	0.002	0.998	0.000
C53.9 Cervix uteri, unspecified	0.002	0.998	0.000
C54.9 Corpus uteri, unspecified	0.002	0.998	0.000
H43.3 Other vitreous opacities	0.002	0.998	0.000
L28.0 Lichen simplex chronicus	0.002	0.998	0.000
Z36.8 Other antenatal screening	0.002	0.998	0.000
H54 Blindness and low vision	0.000	0.998	0.002
A04.8 Other specified bacterial intestinal infections	0.002	0.998	0.000
C83.1 Small cleaved cell (diffuse)	0.001	0.998	0.000
D48.6 Breast	0.001	0.998	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.002	0.998	0.000
M54.4 Lumbago with sciatica	0.002	0.998	0.000
Z36.5 Antenatal screening for isoimmunisation	0.001	0.998	0.000
C93 Monocytic leukaemia	0.002	0.998	0.000
M07 Psoriatic and enteropathic arthropathies	0.002	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.002	0.998	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.001	0.998	0.000
C83.7 Burkitt's tumour	0.001	0.998	0.000
C83.6 Undifferentiated (diffuse)	0.001	0.998	0.000
C83.5 Lymphoblastic (diffuse)	0.001	0.998	0.000
C83.4 Immunoblastic (diffuse)	0.001	0.998	0.000
C83.2 Mixed small and large cell (diffuse)	0.001	0.998	0.000
N35.1 Postinfective urethral stricture, not elsewhere classified	0.001	0.998	0.000
N35.0 Posttraumatic urethral stricture	0.001	0.998	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.001	0.998	0.000
O97 Death from sequelae of direct obstetric causes	0.001	0.998	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.001	0.998	0.000
O95 Obstetric death of unspecified cause	0.001	0.998	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.001	0.998	0.000
N02.9 Unspecified	0.002	0.998	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.001	0.998	0.000
E83.1 Disorders of iron metabolism	0.002	0.998	0.000
H43.2 Crystalline deposits in vitreous body	0.001	0.998	0.000
Q21.1 Atrial septal defect	0.002	0.998	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.001	0.998	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.001	0.998	0.000
H43 Disorders of vitreous body	0.002	0.998	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.001	0.998	0.000
M06.38 Rheumatoid nodule (Other)	0.001	0.998	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.001	0.998	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.001	0.998	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.001	0.998	0.000
M06.33 Rheumatoid nodule (Forearm)	0.001	0.998	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.001	0.998	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.001	0.998	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.001	0.998	0.000
D43.9 Central nervous system, unspecified	0.001	0.998	0.000
D43.7 Other parts of central nervous system	0.001	0.998	0.000
D43.4 Spinal cord	0.001	0.998	0.000
D43.3 Cranial nerves	0.001	0.998	0.000
D43.1 Brain, infratentorial	0.001	0.998	0.000
N80.0 Endometriosis of uterus	0.002	0.998	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.998	0.002
Z35 Supervision of high-risk pregnancy	0.002	0.998	0.000
D43.0 Brain, supratentorial	0.001	0.998	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.001	0.998	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.001	0.998	0.000
Z83.1 Family history of other infectious and parasitic diseases	0.001	0.998	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.001	0.998	0.000
Q23.0 Congenital stenosis of aortic valve	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations