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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs175597
log Bayes Factor = 165.738
Chromosome 6   position 27,810,626  (GRCh37) Explore rs175597 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
D64.9 Anaemia, unspecified
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.000 1.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
N40 Hyperplasia of prostate
0.000 0.000 1.000
M35 Other systemic involvement of connective tissue
1.000 0.000 0.000
D64 Other anaemias
0.999 0.001 0.000
D60-D64 Aplastic and other anaemias
0.999 0.001 0.000
M35.0 Sicca syndrome [Sjogren]
0.999 0.001 0.000
E83.1 Disorders of iron metabolism
0.000 0.001 0.999
K40 Inguinal hernia
0.000 0.001 0.999
Chapter XI Diseases of the digestive system
0.950 0.001 0.049
Chapter XII Diseases of the skin and subcutaneous tissue
0.998 0.002 0.000
K90-K93 Other diseases of the digestive system
0.949 0.003 0.047
E10.3 With ophthalmic complications
0.997 0.003 0.000
D80-D89 Certain disorders involving the immune mechanism
0.996 0.004 0.000
E20-E35 Disorders of other endocrine glands
0.995 0.005 0.000
K40-K46 Hernia
0.001 0.005 0.994
K90 Intestinal malabsorption
0.992 0.005 0.003
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.006 0.994
K44 Diaphragmatic hernia
0.000 0.006 0.994
E27 Other disorders of adrenal gland
0.993 0.007 0.000
H30-H36 Disorders of choroid and retina
0.993 0.007 0.000
E27.1 Primary adrenocortical insufficiency
0.991 0.009 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.989 0.011 0.000
H25-H28 Disorders of lens
0.989 0.011 0.000
D86 Sarcoidosis
0.988 0.012 0.000
H26 Other cataract
0.985 0.015 0.000
H36 Retinal disorders in diseases classified elsewhere
0.985 0.015 0.000
H26.9 Cataract, unspecified
0.984 0.016 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.019 0.981
M05-M14 Inflammatory polyarthropathies
0.981 0.019 0.000
H36.0 Diabetic retinopathy
0.979 0.021 0.000
D86.9 Sarcoidosis, unspecified
0.976 0.024 0.000
N40-N51 Diseases of male genital organs
0.000 0.026 0.974
N42 Other disorders of prostate
0.000 0.029 0.971
L80-L99 Other disorders of the skin and subcutaneous tissue
0.970 0.030 0.000
L20-L30 Dermatitis and eczema
0.969 0.031 0.000
E70-E90 Metabolic disorders
0.965 0.035 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.960 0.040 0.000
E14 Unspecified diabetes mellitus
0.959 0.041 0.000
N32.0 Bladder-neck obstruction
0.000 0.041 0.959
M70-M79 Other soft tissue disorders
0.958 0.042 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.958 0.042 0.000
N39 Other disorders of urinary system
0.000 0.044 0.956
M60-M63 Disorders of muscles
0.955 0.045 0.000
K70-K77 Diseases of liver
0.946 0.045 0.010
N30-N39 Other diseases of urinary system
0.000 0.045 0.955
M23 Internal derangement of knee
0.954 0.046 0.000
N42.8 Other specified disorders of prostate
0.000 0.046 0.954
N32 Other disorders of bladder
0.000 0.048 0.952
M72 Fibroblastic disorders
0.951 0.049 0.000
L50-L54 Urticaria and erythema
0.948 0.052 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.948 0.052 0.000
K75 Other inflammatory liver diseases
0.946 0.053 0.001
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.946 0.054 0.000
N39.8 Other specified disorders of urinary system
0.000 0.054 0.946
K35-K38 Diseases of appendix
0.920 0.055 0.024
K75.4 Autoimmune hepatitis
0.943 0.057 0.000
E78.5 Hyperlipidaemia, unspecified
0.937 0.063 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.935 0.065 0.000
M31 Other necrotising vasculopathies
0.933 0.067 0.000
M11 Other crystal arthropathies
0.928 0.072 0.000
M62 Other disorders of muscle
0.928 0.072 0.000
L30 Other dermatitis
0.926 0.074 0.000
M22 Disorders of patella
0.926 0.074 0.000
E10.1 With ketoacidosis
0.925 0.075 0.000
M10 Gout
0.923 0.077 0.000
H34 Retinal vascular occlusions
0.923 0.077 0.000
N39.0 Urinary tract infection, site not specified
0.000 0.079 0.921
E10.2 With renal complications
0.916 0.084 0.000
M34 Systemic sclerosis
0.914 0.086 0.000
K35 Acute appendicitis
0.913 0.086 0.001
N42.1 Congestion and haemorrhage of prostate
0.000 0.087 0.913
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.907 0.093 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.904 0.096 0.000
E14.3 With ophthalmic complications
0.904 0.096 0.000
K35.9 Acute appendicitis, unspecified
0.902 0.098 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.902 0.098 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.900 0.100 0.000
L30.9 Dermatitis, unspecified
0.897 0.103 0.000
L10-L14 Bullous disorders
0.896 0.104 0.000
L40-L45 Papulosquamous disorders
0.894 0.106 0.000
H43-H45 Disorders of vitreous body and globe
0.892 0.108 0.000
L93 Lupus erythematosus
0.890 0.110 0.000
K90.9 Intestinal malabsorption, unspecified
0.885 0.114 0.001
M62.8 Other specified disorders of muscle
0.882 0.118 0.000
M20.1 Hallux valgus (acquired)
0.000 0.118 0.882
L94 Other localised connective tissue disorders
0.882 0.118 0.000
E10.4 With neurological complications
0.881 0.119 0.000
M20 Acquired deformities of fingers and toes
0.001 0.120 0.879
N39.9 Disorder of urinary system, unspecified
0.000 0.124 0.876
M11.2 Other chondrocalcinosis
0.875 0.125 0.000
L52 Erythema nodosum
0.874 0.126 0.000
M20.5 Other deformities of toe(s) (acquired)
0.000 0.126 0.874
L28 Lichen simplex chronicus and prurigo
0.871 0.129 0.000
N36 Other disorders of urethra
0.000 0.130 0.870
M31.6 Other giant cell arteritis
0.869 0.131 0.000
K72 Hepatic failure, not elsewhere classified
0.865 0.132 0.003
E78.6 Lipoprotein deficiency
0.866 0.134 0.000
K75.8 Other specified inflammatory liver diseases
0.864 0.136 0.000
M15-M19 Arthrosis
0.864 0.136 0.000
M35.3 Polymyalgia rheumatica
0.863 0.137 0.000
H34.8 Other retinal vascular occlusions
0.861 0.139 0.000
L43 Lichen planus
0.861 0.139 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.861 0.139 0.000
K51 Ulcerative colitis
0.000 0.144 0.855
N39.3 Stress incontinence
0.000 0.145 0.855
K51.2 Ulcerative (chronic) proctitis
0.000 0.146 0.854
M17 Gonarthrosis [arthrosis of knee]
0.852 0.148 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.152 0.848
K73 Chronic hepatitis, not elsewhere classified
0.842 0.154 0.004
E16.0 Drug-induced hypoglycaemia without coma
0.844 0.156 0.000
L43.9 Lichen planus, unspecified
0.840 0.160 0.000
M22.3 Other derangements of patella
0.838 0.162 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.838 0.162 0.000
M10.0 Idiopathic gout
0.831 0.169 0.000
H43 Disorders of vitreous body
0.831 0.169 0.000
M17.9 Gonarthrosis, unspecified
0.830 0.170 0.000
M20.4 Other hammer toe(s) (acquired)
0.000 0.172 0.828
E78.9 Disorder of lipoprotein metabolism, unspecified
0.827 0.173 0.000
L27 Dermatitis due to substances taken internally
0.826 0.174 0.000
N34 Urethritis and urethral syndrome
0.000 0.176 0.824
H02 Other disorders of eyelid
0.823 0.177 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.822 0.178 0.000
M23.3 Other meniscus derangements
0.819 0.181 0.000
E20 Hypoparathyroidism
0.819 0.181 0.000
H43.1 Vitreous haemorrhage
0.817 0.183 0.000
L89 Decubitus ulcer
0.814 0.186 0.000
H27 Other disorders of lens
0.813 0.187 0.000
D80 Immunodeficiency with predominantly antibody defects
0.812 0.188 0.000
E83 Disorders of mineral metabolism
0.741 0.189 0.070
E23 Hypofunction and other disorders of pituitary gland
0.810 0.190 0.000
E78.1 Pure hyperglyceridaemia
0.810 0.190 0.000
M75 Shoulder lesions
0.807 0.193 0.000
H46 Optic neuritis
0.806 0.194 0.000
M10.9 Gout, unspecified
0.806 0.194 0.000
N36.2 Urethral caruncle
0.000 0.194 0.806
Q50-Q56 Congenital malformations of genital organs
0.806 0.194 0.000
K35.1 Acute appendicitis with peritoneal abscess
0.805 0.195 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.804 0.196 0.000
E10.5 With peripheral circulatory complications
0.803 0.197 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.802 0.197 0.001
D83 Common variable immunodeficiency
0.803 0.197 0.000
K46 Unspecified abdominal hernia
0.001 0.197 0.802
I70-I79 Diseases of arteries, arterioles and capillaries
0.802 0.198 0.000
M23.9 Internal derangement of knee, unspecified
0.802 0.198 0.000
H26.1 Traumatic cataract
0.801 0.199 0.000
M24 Other specific joint derangements
0.801 0.199 0.000
Chapter XIV Diseases of the genitourinary system
0.002 0.199 0.799
E14.9 Without complications
0.799 0.201 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.201 0.799
M23.6 Other spontaneous disruption of ligament(s) of knee
0.796 0.204 0.000
K72.0 Acute and subacute hepatic failure
0.795 0.204 0.001
H02.5 Other disorders affecting eyelid function
0.795 0.205 0.000
L93.0 Discoid lupus erythematosus
0.795 0.205 0.000
H47.2 Optic atrophy
0.795 0.205 0.000
L92.0 Granuloma annulare
0.791 0.209 0.000
N42.9 Disorder of prostate, unspecified
0.000 0.209 0.791
I73 Other peripheral vascular diseases
0.791 0.209 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.789 0.211 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.789 0.211 0.000
K51.4 Pseudopolyposis of colon
0.000 0.211 0.788
H01 Other inflammation of eyelid
0.788 0.212 0.000
M22.8 Other disorders of patella
0.787 0.213 0.000
E07 Other disorders of thyroid
0.785 0.215 0.000
H02.1 Ectropion of eyelid
0.785 0.215 0.000
D86.8 Sarcoidosis of other and combined sites
0.785 0.215 0.000
M17.1 Other primary gonarthrosis
0.784 0.216 0.000
I73.9 Peripheral vascular disease, unspecified
0.783 0.217 0.000
M23.4 Loose body in knee
0.782 0.218 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.782 0.218 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.781 0.219 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.781 0.219 0.000
H31 Other disorders of choroid
0.781 0.219 0.000
L81 Other disorders of pigmentation
0.779 0.221 0.000
N46 Male infertility
0.000 0.221 0.779
N41 Inflammatory diseases of prostate
0.000 0.222 0.778
E31 Polyglandular dysfunction
0.778 0.222 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.778 0.222 0.000
M75.0 Adhesive capsulitis of shoulder
0.777 0.223 0.000
L80 Vitiligo
0.777 0.223 0.000
D86.1 Sarcoidosis of lymph nodes
0.776 0.224 0.000
M34.1 CR(E)ST syndrome
0.776 0.224 0.000
D50-D53 Nutritional anaemias
0.774 0.226 0.000
H47.3 Other disorders of optic disk
0.774 0.226 0.000
M76 Enthesopathies of lower limb, excluding foot
0.774 0.226 0.000
L28.0 Lichen simplex chronicus
0.774 0.226 0.000
M35.7 Hypermobility syndrome
0.773 0.227 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.227 0.772
E50-E64 Other nutritional deficiencies
0.772 0.228 0.000
M35.1 Other overlap syndromes
0.771 0.229 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.771 0.229 0.000
L50 Urticaria
0.771 0.229 0.000
H26.4 After-cataract
0.770 0.230 0.000
K75.9 Inflammatory liver disease, unspecified
0.769 0.230 0.000
H30 Chorioretinal inflammation
0.768 0.232 0.000
D55-D59 Haemolytic anaemias
0.768 0.232 0.000
E78.4 Other hyperlipidaemia
0.766 0.234 0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.237 0.763
M23.0 Cystic meniscus
0.761 0.239 0.000
D86.3 Sarcoidosis of skin
0.758 0.242 0.000
M32 Systemic lupus erythematosus
0.758 0.242 0.000
E84 Cystic fibrosis
0.758 0.242 0.000
I77 Other disorders of arteries and arterioles
0.758 0.242 0.000
L53 Other erythematous conditions
0.758 0.242 0.000
E78.8 Other disorders of lipoprotein metabolism
0.757 0.243 0.000
N42.0 Calculus of prostate
0.000 0.244 0.756
M65-M68 Disorders of synovium and tendon
0.755 0.245 0.000
M34.9 Systemic sclerosis, unspecified
0.754 0.246 0.000
K36 Other appendicitis
0.738 0.250 0.013
K73.2 Chronic active hepatitis, not elsewhere classified
0.748 0.250 0.002
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.749 0.251 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.251 0.749
E74 Other disorders of carbohydrate metabolism
0.747 0.253 0.000
L94.0 Localised scleroderma [morphea]
0.746 0.254 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.746 0.254 0.000
M62.6 Muscle strain
0.745 0.255 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.745 0.255 0.000
E10.0 With coma
0.743 0.257 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.743 0.257 0.000
E73 Lactose intolerance
0.743 0.257 0.000
E10.6 With other specified complications
0.740 0.260 0.000
L93.2 Other local lupus erythematosus
0.740 0.260 0.000
L13 Other bullous disorders
0.739 0.261 0.000
K35.0 Acute appendicitis with generalised peritonitis
0.738 0.262 0.000
D84 Other immunodeficiencies
0.737 0.263 0.000
H34.2 Other retinal artery occlusions
0.735 0.264 0.000
M10.07 Idiopathic gout (Ankle and foot)
0.735 0.265 0.000
M11.9 Crystal arthropathy, unspecified
0.735 0.265 0.000
E06 Thyroiditis
0.735 0.265 0.000
H01.0 Blepharitis
0.734 0.266 0.000
K50-K52 Noninfective enteritis and colitis
0.172 0.266 0.562
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.734 0.266 0.000
M62.81 Other specified disorders of muscle (Shoulder region)
0.733 0.266 0.000
N45 Orchitis and epididymitis
0.000 0.267 0.733
E80 Disorders of porphyrin and bilirubin metabolism
0.732 0.268 0.000
M22.2 Patellofemoral disorders
0.732 0.268 0.000
E24 Cushing's syndrome
0.732 0.268 0.000
M13 Other arthritis
0.730 0.268 0.001
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.731 0.269 0.000
E13 Other specified diabetes mellitus
0.731 0.269 0.000
Chapter IX Diseases of the circulatory system
0.731 0.269 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.730 0.270 0.000
M62.83 Other specified disorders of muscle (Forearm)
0.730 0.270 0.000
M34.8 Other forms of systemic sclerosis
0.728 0.272 0.000
M31.1 Thrombotic microangiopathy
0.726 0.274 0.000
L11 Other acantholytic disorders
0.724 0.276 0.000
K41 Femoral hernia
0.001 0.277 0.723
M33 Dermatopolymyositis
0.723 0.277 0.000
E14.2 Withrenal complications
0.722 0.277 0.000
L12 Pemphigoid
0.722 0.278 0.000
E27.9 Disorder of adrenal gland, unspecified
0.722 0.278 0.000
E10.8 With unspecified complications
0.720 0.279 0.000
M12 Other specific arthropathies
0.720 0.280 0.000
I74 Arterial embolism and thrombosis
0.719 0.281 0.000
E27.2 Addisonian crisis
0.718 0.282 0.000
M07 Psoriatic and enteropathic arthropathies
0.718 0.282 0.000
H53-H54 Visual disturbances and blindness
0.718 0.282 0.000
L23 Allergic contact dermatitis
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.717 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.717 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.717 0.283 0.000
E16.3 Increased secretion of glucagon
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.717 0.283 0.000
M35.8 Other specified systemic involvement of connective tissue
0.717 0.283 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.717 0.283 0.000
M35.5 Multifocal fibrosclerosis
0.717 0.283 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.717 0.283 0.000
D64.4 Congenital dyserythropoietic anaemia
0.717 0.283 0.000
D64.3 Other sideroblastic anaemias
0.717 0.283 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.717 0.283 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.717 0.283 0.000
D64.0 Hereditary sideroblastic anaemia
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.716 0.283 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.284 0.716
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.284 0.716
M62.80 Other specified disorders of muscle (Multiple sites)
0.715 0.285 0.000
D86.0 Sarcoidosis of lung
0.715 0.285 0.000
N32.1 Vesicointestinal fistula
0.000 0.285 0.715
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.715 0.285 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.681 0.285 0.034
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.285 0.715
D82 Immunodeficiency associated with other major defects
0.714 0.286 0.000
D81 Combined immunodeficiencies
0.714 0.286 0.000
E16.1 Other hypoglycaemia
0.714 0.286 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.713 0.287 0.000
E32 Diseases of thymus
0.713 0.287 0.000
E30 Disorders of puberty, not elsewhere classified
0.713 0.287 0.000
E25 Adrenogenital disorders
0.713 0.287 0.000
K90.3 Pancreatic steatorrhoea
0.711 0.287 0.002
K90.2 Blind loop syndrome, not elsewhere classified
0.711 0.287 0.002
K90.1 Tropical sprue
0.711 0.287 0.002
K44.1 Diaphragmatic hernia with gangrene
0.000 0.287 0.712
E27.5 Adrenomedullary hyperfunction
0.712 0.288 0.000
E27.0 Other adrenocortical overactivity
0.712 0.288 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.712 0.288 0.000
H02.0 Entropion and trichiasis of eyelid
0.712 0.288 0.000
M00-M03 Infectious arthropathies
0.710 0.290 0.000
M06 Other rheumatoid arthritis
0.709 0.291 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.709 0.291 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.709 0.291 0.000
E14.1 With ketoacidosis
0.709 0.291 0.000
K35.2 Acute appendicitis with generalized peritonitis
0.707 0.292 0.001
I70 Atherosclerosis
0.707 0.293 0.000
M62.0 Diastasis of muscle
0.707 0.293 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.706 0.294 0.000
H26.3 Drug-induced cataract
0.706 0.294 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.706 0.294 0.000
N36.3 Prolapsed urethral mucosa
0.000 0.295 0.705
M35.2 Behcet's disease
0.704 0.296 0.000
H47.0 Disorders of optic nerve, not elsewhere classified
0.703 0.297 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.703 0.297 0.000
M08 Juvenile arthritis
0.703 0.297 0.000
M30 Polyarteritis nodosa and related conditions
0.702 0.297 0.000
M10.90 Gout, unspecified (Multiple sites)
0.702 0.298 0.000
L94.2 Calcinosis cutis
0.701 0.299 0.000
I77.6 Arteritis, unspecified
0.701 0.299 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.701 0.299 0.000
N34.2 Other urethritis
0.000 0.300 0.700
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.302 0.698
N44 Torsion of testis
0.000 0.302 0.698
L84 Corns and callosities
0.696 0.303 0.000
D61 Other aplastic anaemias
0.696 0.304 0.000
N42.3 Dysplasia of prostate
0.000 0.304 0.696
L81.9 Disorder of pigmentation, unspecified
0.696 0.304 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.695 0.305 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.695 0.305 0.000
L87 Transepidermal elimination disorders
0.695 0.305 0.000
L88 Pyoderma gangrenosum
0.695 0.305 0.000
L86 Keratoderma in diseases classified elsewhere
0.695 0.305 0.000
L25 Unspecified contact dermatitis
0.695 0.305 0.000
L24 Irritant contact dermatitis
0.695 0.305 0.000
L26 Exfoliative dermatitis
0.695 0.305 0.000
L22 Diaper [napkin] dermatitis
0.695 0.305 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.694 0.306 0.000
E83.5 Disorders of calcium metabolism
0.690 0.306 0.004
E20.9 Hypoparathyroidism, unspecified
0.693 0.307 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.693 0.307 0.000
E79 Disorders of purine and pyrimidine metabolism
0.692 0.308 0.000
E77 Disorders of glycoprotein metabolism
0.692 0.308 0.000
E76 Disorders of glycosaminoglycan metabolism
0.692 0.308 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.692 0.308 0.000
E72 Other disorders of amino-acid metabolism
0.692 0.308 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.692 0.308 0.000
E70 Disorders of aromatic amino-acid metabolism
0.692 0.308 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.692 0.308 0.000
L28.1 Prurigo nodularis
0.692 0.308 0.000
M23.1 Discoid meniscus (congenital)
0.692 0.308 0.000
Q00-Q07 Congenital malformations of the nervous system
0.692 0.308 0.000
Q39 Congenital malformations of oesophagus
0.691 0.309 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.689 0.311 0.000
I77.1 Stricture of artery
0.689 0.311 0.000
E78.3 Hyperchylomicronaemia
0.688 0.312 0.000
E14.8 With unspecified complications
0.688 0.312 0.000
E14.7 With multiple complications
0.688 0.312 0.000
E14.6 With other specified complications
0.688 0.312 0.000
E14.5 With peripheral circulatory complications
0.688 0.312 0.000
E14.0 With coma
0.688 0.312 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.688 0.312 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.687 0.313 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.687 0.313 0.000
Q51 Congenital malformations of uterus and cervix
0.687 0.313 0.000
N39.2 Orthostatic proteinuria, unspecified
0.000 0.314 0.685
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.000 0.315 0.685
M63 Disorders of muscle in diseases classified elsewhere
0.685 0.315 0.000
M61 Calcification and ossification of muscle
0.685 0.315 0.000
K77 Liver disorders in diseases classified elsewhere
0.678 0.315 0.007
K71 Toxic liver disease
0.678 0.315 0.007
N37 Urethral disorders in diseases classified elsewhere
0.000 0.315 0.685
N33 Bladder disorders in diseases classified elsewhere
0.000 0.315 0.685
L89.9 Decubitus ulcer and pressure area, unspecified
0.685 0.315 0.000
L94.9 Localised connective tissue disorder, unspecified
0.684 0.315 0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.683 0.317 0.000
N32.4 Rupture of bladder, nontraumatic
0.000 0.317 0.682
N32.2 Vesical fistula, not elsewhere classified
0.000 0.317 0.682
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.317 0.682
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.318 0.682
M72.9 Fibroblastic disorder, unspecified
0.682 0.318 0.000
M72.8 Other fibroblastic disorders
0.682 0.318 0.000
M72.6 Necrotizing fasciitis
0.682 0.318 0.000
M72.5 Fasciitis, not elsewhere classified
0.682 0.318 0.000
M72.4 Pseudosarcomatous fibromatosis
0.682 0.318 0.000
M72.3 Nodular fasciitis
0.682 0.318 0.000
M72.1 Knuckle pads
0.682 0.318 0.000
K90.8 Other intestinal malabsorption
0.680 0.318 0.002
M24.1 Other articular cartilage disorders
0.682 0.318 0.000
H47.1 Papilloedema, unspecified
0.680 0.319 0.000
L20 Atopic dermatitis
0.680 0.320 0.000
L54 Erythema in diseases classified elsewhere
0.680 0.320 0.000
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec
0.680 0.320 0.000
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other
0.680 0.320 0.000
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot
0.680 0.320 0.000
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg
0.680 0.320 0.000
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh
0.680 0.320 0.000
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm
0.680 0.320 0.000
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm
0.680 0.320 0.000
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region
0.680 0.320 0.000
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites
0.680 0.320 0.000
E11 Non-insulin-dependent diabetes mellitus
0.679 0.321 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.678 0.321 0.001
K75.2 Nonspecific reactive hepatitis
0.678 0.321 0.001
K75.1 Phlebitis of portal vein
0.678 0.321 0.001
M13.0 Polyarthritis, unspecified
0.678 0.321 0.001
N36.0 Urethral fistula
0.000 0.322 0.678
L94.8 Other specified localised connective tissue disorders
0.678 0.322 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.677 0.323 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.676 0.324 0.000
M10.94 Gout, unspecified (Hand)
0.674 0.325 0.000
Q43 Other congenital malformations of intestine
0.674 0.326 0.000
L51 Erythema multiforme
0.674 0.326 0.000
Chapter XX External causes of morbidity and mortality
0.674 0.326 0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)
0.673 0.327 0.000
E05.8 Other thyrotoxicosis
0.671 0.329 0.000
M10.06 Idiopathic gout (Lower leg)
0.671 0.329 0.000
L50.0 Allergic urticaria
0.670 0.330 0.000
M22.0 Recurrent dislocation of patella
0.670 0.330 0.000
M31.9 Necrotising vasculopathy, unspecified
0.669 0.331 0.000
M31.8 Other specified necrotising vasculopathies
0.669 0.331 0.000
M31.7 Microscopic polyangiitis
0.669 0.331 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.669 0.331 0.000
M31.2 Lethal midline granuloma
0.669 0.331 0.000
M31.0 Hypersensitivity angiitis
0.669 0.331 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.669 0.331 0.000
E78.2 Mixed hyperlipidaemia
0.668 0.332 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.667 0.333 0.000
M11.8 Other specified crystal arthropathies
0.665 0.335 0.000
M11.1 Familial chondrocalcinosis
0.665 0.335 0.000
M11.0 Hydroxyapatite deposition disease
0.665 0.335 0.000
M62.9 Disorder of muscle, unspecified
0.665 0.335 0.000
M62.4 Contracture of muscle
0.665 0.335 0.000
M62.3 Immobility syndrome (paraplegic)
0.665 0.335 0.000
M62.2 Ischaemic infarction of muscle
0.665 0.335 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.665 0.335 0.000
D83.9 Common variable immunodeficiency, unspecified
0.665 0.335 0.000
E03.8 Other specified hypothyroidism
0.664 0.336 0.000
L30.5 Pityriasis alba
0.664 0.336 0.000
L30.4 Erythema intertrigo
0.664 0.336 0.000
L30.3 Infective dermatitis
0.664 0.336 0.000
L30.2 Cutaneous autosensitisation
0.664 0.336 0.000
L30.1 Dyshidrosis [pompholyx]
0.664 0.336 0.000
L30.0 Nummular dermatitis
0.664 0.336 0.000
M22.1 Recurrent subluxation of patella
0.664 0.336 0.000
M22.9 Disorder of patella, unspecified
0.664 0.336 0.000
H27.0 Aphakia
0.663 0.337 0.000
K72.9 Hepatic failure, unspecified
0.662 0.337 0.001
M23.49 Loose body in knee-Unspec lig/men
0.663 0.337 0.000
L27.1 Localised skin eruption due to drugs and medicaments
0.663 0.337 0.000
M10.4 Other secondary gout
0.662 0.338 0.000
M10.3 Gout due to impairment of renal function
0.662 0.338 0.000
M10.2 Drug-induced gout
0.662 0.338 0.000
M10.1 Lead-induced gout
0.662 0.338 0.000
H34.9 Retinal vascular occlusion, unspecified
0.661 0.338 0.000
H34.0 Transient retinal artery occlusion
0.661 0.338 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.662 0.338 0.000
M14 Arthropathies in other diseases classified elsewhere
0.661 0.338 0.000
Q53 Undescended testicle
0.661 0.339 0.000
L89.2 Stage III decubitus ulcer
0.661 0.339 0.000
M67 Other disorders of synovium and tendon
0.660 0.340 0.000
L21 Seborrhoeic dermatitis
0.659 0.341 0.000
E14.4 With neurological complications
0.659 0.341 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.658 0.342 0.000
M15 Polyarthrosis
0.658 0.342 0.000
K73.9 Chronic hepatitis, unspecified
0.655 0.343 0.002
M70 Soft tissue disorders related to use, overuse and pressure
0.656 0.344 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.655 0.345 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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