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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17589290
log Bayes Factor = 2.83438
Chromosome 4   position 112,923,237  (GRCh37) Explore rs17589290 on Ensembl!
Variant rs17589290 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.999 0.001 0.000
Chapter II Neoplasms
0.981 0.019 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.973 0.027 0.000
Chapter IX Diseases of the circulatory system
0.968 0.032 0.000
D10-D36 Benign neoplasms
0.941 0.059 0.000
Chapter VII Diseases of the eye and adnexa
0.940 0.060 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.906 0.094 0.000
Chapter X Diseases of the respiratory system
0.890 0.110 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.883 0.117 0.000
Chapter XX External causes of morbidity and mortality
0.881 0.119 0.000
I20-I25 Ischaemic heart diseases
0.867 0.133 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.865 0.135 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.863 0.137 0.000
Chapter XIV Diseases of the genitourinary system
0.860 0.140 0.000
S00-S09 Injuries to the head
0.835 0.165 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.826 0.174 0.000
D27 Benign neoplasm of ovary
0.825 0.175 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.822 0.178 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.818 0.182 0.000
Chapter XXI Factors influencing health status and contact with health services
0.815 0.185 0.000
T81 Complications of procedures, not elsewhere classified
0.812 0.188 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.809 0.191 0.000
H25-H28 Disorders of lens
0.804 0.196 0.000
Chapter V Mental and behavioural disorders
0.798 0.202 0.000
C51-C58 Malignant neoplasms of female genital organs
0.798 0.202 0.000
D25 Leiomyoma of uterus
0.793 0.207 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.791 0.209 0.000
J20-J22 Other acute lower respiratory infections
0.790 0.210 0.000
Chapter I Certain infectious and parasitic diseases
0.789 0.211 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.783 0.217 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.783 0.217 0.000
Chapter XI Diseases of the digestive system
0.760 0.240 0.000
I30-I52 Other forms of heart disease
0.760 0.240 0.000
I25 Chronic ischaemic heart disease
0.756 0.244 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.751 0.249 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.750 0.250 0.000
I60-I69 Cerebrovascular diseases
0.746 0.253 0.000
J95-J99 Other diseases of the respiratory system
0.745 0.255 0.000
H40-H42 Glaucoma
0.745 0.255 0.000
D12.2 Ascending colon
0.740 0.260 0.000
D00-D09 In situ neoplasms
0.738 0.262 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.736 0.264 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.735 0.265 0.000
H02 Other disorders of eyelid
0.731 0.269 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.730 0.270 0.000
J30-J39 Other diseases of upper respiratory tract
0.729 0.271 0.000
E65-E68 Obesity and other hyperalimentation
0.729 0.271 0.000
S50-S59 Injuries to the elbow and forearm
0.727 0.273 0.000
Z51 Other medical care
0.727 0.273 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.725 0.275 0.000
S01 Open wound of head
0.718 0.282 0.000
J22 Unspecified acute lower respiratory infection
0.718 0.282 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.718 0.282 0.000
O60-O75 Complications of labour and delivery
0.717 0.282 0.000
Chapter XXII Codes for special purposes
0.716 0.284 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.716 0.284 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.716 0.284 0.000
I20 Angina pectoris
0.714 0.286 0.000
I73 Other peripheral vascular diseases
0.711 0.289 0.000
N17-N19 Renal failure
0.705 0.295 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.704 0.296 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.704 0.296 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.704 0.296 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.704 0.296 0.000
C64-C68 Malignant neoplasms of urinary tract
0.704 0.296 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.704 0.296 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.704 0.296 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.704 0.296 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.699 0.300 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.699 0.301 0.000
Chapter VIII Diseases of the ear and mastoid process
0.699 0.301 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.699 0.301 0.000
D17 Benign lipomatous neoplasm
0.699 0.301 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.698 0.302 0.000
T79-T79 Certain early complications of trauma
0.698 0.302 0.000
T66-T78 Other and unspecified effects of external causes
0.698 0.302 0.000
T33-T35 Frostbite
0.698 0.302 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.698 0.302 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.698 0.302 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.698 0.302 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.698 0.302 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.698 0.302 0.000
T00-T07 Injuries involving multiple body regions
0.698 0.302 0.000
S90-S99 Injuries to the ankle and foot
0.698 0.302 0.000
S80-S89 Injuries to the knee and lower leg
0.698 0.302 0.000
S70-S79 Injuries to the hip and thigh
0.698 0.302 0.000
S40-S49 Injuries to the shoulder and upper arm
0.698 0.302 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.698 0.302 0.000
S20-S29 Injuries to the thorax
0.698 0.302 0.000
S10-S19 Injuries to the neck
0.698 0.302 0.000
C50-C50 Malignant neoplasm of breast
0.697 0.303 0.000
I05-I09 Chronic rheumatic heart diseases
0.694 0.306 0.000
I00-I02 Acute rheumatic fever
0.694 0.306 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.693 0.307 0.000
S60-S69 Injuries to the wrist and hand
0.692 0.308 0.000
N10-N16 Renal tubulo-interstitial diseases
0.691 0.309 0.000
Chapter VI Diseases of the nervous system
0.691 0.309 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.689 0.311 0.000
C15-C26 Malignant neoplasms of digestive organs
0.688 0.312 0.000
J60-J70 Lung diseases due to external agents
0.687 0.313 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.682 0.318 0.000
I74 Arterial embolism and thrombosis
0.682 0.318 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.678 0.322 0.000
H30-H36 Disorders of choroid and retina
0.678 0.322 0.000
H26 Other cataract
0.676 0.324 0.000
E70-E90 Metabolic disorders
0.676 0.324 0.000
E50-E64 Other nutritional deficiencies
0.675 0.325 0.000
D36 Benign neoplasm of other and unspecified sites
0.674 0.325 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.674 0.325 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.674 0.325 0.000
D32 Benign neoplasm of meninges
0.674 0.325 0.000
D31 Benign neoplasm of eye and adnexa
0.674 0.325 0.000
D30 Benign neoplasm of urinary organs
0.674 0.325 0.000
D29 Benign neoplasm of male genital organs
0.674 0.325 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.674 0.325 0.000
D26 Other benign neoplasms of uterus
0.674 0.325 0.000
D23 Other benign neoplasms of skin
0.674 0.325 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.674 0.325 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.674 0.325 0.000
D19 Benign neoplasm of mesothelial tissue
0.674 0.325 0.000
D18 Haemangioma and lymphangioma, any site
0.674 0.325 0.000
D16 Benign neoplasm of bone and articular cartilage
0.674 0.325 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.674 0.325 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.674 0.325 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.674 0.325 0.000
D11 Benign neoplasm of major salivary glands
0.674 0.325 0.000
D10 Benign neoplasm of mouth and pharynx
0.674 0.325 0.000
D34 Benign neoplasm of thyroid gland
0.674 0.325 0.000
D24 Benign neoplasm of breast
0.674 0.325 0.000
H55-H59 Other disorders of eye and adnexa
0.674 0.326 0.000
H53-H54 Visual disturbances and blindness
0.674 0.326 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.674 0.326 0.000
H43-H45 Disorders of vitreous body and globe
0.674 0.326 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.674 0.326 0.000
H10-H13 Disorders of conjunctiva
0.674 0.326 0.000
I71 Aortic aneurysm and dissection
0.672 0.328 0.000
E00-E07 Disorders of thyroid gland
0.670 0.330 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.667 0.333 0.000
C54 Malignant neoplasm of corpus uteri
0.666 0.334 0.000
W00-W19 Falls
0.664 0.336 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.662 0.338 0.000
Z45 Adjustment and management of implanted device
0.661 0.338 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.661 0.339 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.660 0.340 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.656 0.344 0.000
I77 Other disorders of arteries and arterioles
0.655 0.344 0.000
D12.3 Transverse colon
0.655 0.345 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.655 0.345 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.654 0.346 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.650 0.350 0.000
K55-K64 Other diseases of intestines
0.649 0.351 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.649 0.351 0.000
T87 Complications peculiar to reattachment and amputation
0.649 0.351 0.000
T86 Failure and rejection of transplanted organs and tissues
0.649 0.351 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.649 0.351 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.649 0.351 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.648 0.352 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.647 0.353 0.000
C79 Secondary malignant neoplasm of other sites
0.646 0.353 0.000
I84 Haemorrhoids
0.644 0.356 0.000
D22 Melanocytic naevi
0.644 0.356 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.643 0.356 0.000
D25.9 Leiomyoma of uterus, unspecified
0.643 0.357 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.642 0.358 0.000
H02.8 Other specified disorders of eyelid
0.642 0.358 0.000
J98 Other respiratory disorders
0.641 0.359 0.000
O00-O08 Pregnancy with abortive outcome
0.639 0.360 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.638 0.362 0.000
J00-J06 Acute upper respiratory infections
0.638 0.362 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.637 0.363 0.000
Z51.2 Other chemotherapy
0.636 0.364 0.000
S09 Other and unspecified injuries of head
0.633 0.367 0.000
D25.1 Intramural leiomyoma of uterus
0.633 0.367 0.000
E40-E46 Malnutrition
0.633 0.367 0.000
E20-E35 Disorders of other endocrine glands
0.633 0.367 0.000
N25-N29 Other disorders of kidney and ureter
0.632 0.368 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.632 0.368 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.632 0.368 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.632 0.368 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.632 0.368 0.000
Y35-Y36 Legal intervention and operations of war
0.632 0.368 0.000
Y10-Y34 Event of undetermined intent
0.632 0.368 0.000
Y00-Y09 Assault
0.632 0.368 0.000
X85-X99 Assault
0.632 0.368 0.000
X60-X84 Intentional self-harm
0.632 0.368 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.632 0.368 0.000
X50-X57 Overexertion, travel and privation
0.632 0.368 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.632 0.368 0.000
X30-X39 Exposure to forces of nature
0.632 0.368 0.000
X20-X29 Contact with venomous animals and plants
0.632 0.368 0.000
X10-X19 Contact with heat and hot substances
0.632 0.368 0.000
X00-X09 Exposure to smoke, fire and flames
0.632 0.368 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.632 0.368 0.000
W75-W84 Other accidental threats to breathing
0.632 0.368 0.000
W65-W74 Accidental drowning and submersion
0.632 0.368 0.000
W50-W64 Exposure to animate mechanical forces
0.632 0.368 0.000
W20-W49 Exposure to inanimate mechanical forces
0.632 0.368 0.000
V98-V99 Other and unspecified transport accidents
0.632 0.368 0.000
V95-V97 Air and space transport accidents
0.632 0.368 0.000
V90-V94 Water transport accidents
0.632 0.368 0.000
V80-V89 Other land transport accidents
0.632 0.368 0.000
V70-V79 Bus occupant injured in transport accident
0.632 0.368 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.632 0.368 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.632 0.368 0.000
V40-V49 Car occupant injured in transport accident
0.632 0.368 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.632 0.368 0.000
V20-V29 Motorcycle rider injured in transport accident
0.632 0.368 0.000
V10-V19 Pedal cyclist injured in transport accident
0.632 0.368 0.000
V01-V09 Pedestrian injured in transport accident
0.632 0.368 0.000
I10-I15 Hypertensive diseases
0.632 0.368 0.000
H25 Senile cataract
0.631 0.369 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.626 0.374 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.626 0.374 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.625 0.375 0.000
I24 Other acute ischaemic heart diseases
0.621 0.378 0.000
I23 Certain current complications following acute myocardial infarction
0.621 0.378 0.000
I22 Subsequent myocardial infarction
0.621 0.378 0.000
F30-F39 Mood [affective] disorders
0.621 0.379 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.620 0.380 0.000
O85-O92 Complications predominantly related to the puerperium
0.620 0.380 0.000
O80-O84 Delivery
0.620 0.380 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.620 0.380 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.620 0.380 0.000
E10-E14 Diabetes mellitus
0.620 0.380 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.619 0.381 0.000
I78 Diseases of capillaries
0.619 0.381 0.000
I72 Other aneurysm
0.619 0.381 0.000
I70 Atherosclerosis
0.619 0.381 0.000
E66 Obesity
0.619 0.381 0.000
L20-L30 Dermatitis and eczema
0.618 0.382 0.000
D12.4 Descending colon
0.618 0.382 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.617 0.383 0.000
N99-N99 Other disorders of the genitourinary system
0.616 0.384 0.000
N60-N64 Disorders of breast
0.616 0.384 0.000
N00-N08 Glomerular diseases
0.616 0.384 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.615 0.385 0.000
I31 Other diseases of pericardium
0.609 0.391 0.000
N40-N51 Diseases of male genital organs
0.608 0.392 0.000
I21 Acute myocardial infarction
0.607 0.393 0.000
Z46 Fitting and adjustment of other devices
0.607 0.393 0.000
S01.8 Open wound of other parts of head
0.607 0.393 0.000
H40 Glaucoma
0.605 0.395 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.605 0.395 0.000
Z51.5 Palliative care
0.603 0.397 0.000
A00-A09 Intestinal infectious diseases
0.602 0.398 0.000
I20.9 Angina pectoris, unspecified
0.600 0.400 0.000
B95-B98 Bacterial, viral and other infectious agents
0.600 0.400 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.600 0.400 0.000
I47 Paroxysmal tachycardia
0.600 0.400 0.000
S08 Traumatic amputation of part of head
0.598 0.401 0.000
S07 Crushing injury of head
0.598 0.401 0.000
S06 Intracranial injury
0.598 0.401 0.000
S05 Injury of eye and orbit
0.598 0.401 0.000
S04 Injury of cranial nerves
0.598 0.401 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.598 0.401 0.000
S02 Fracture of skull and facial bones
0.598 0.401 0.000
S00 Superficial injury of head
0.598 0.401 0.000
N17 Acute renal failure
0.598 0.402 0.000
C60-C63 Malignant neoplasms of male genital organs
0.598 0.402 0.000
Z48 Other surgical follow-up care
0.596 0.403 0.000
N30-N39 Other diseases of urinary system
0.595 0.404 0.000
B35-B49 Mycoses
0.593 0.407 0.000
C80 Malignant neoplasm without specification of site
0.592 0.408 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.592 0.408 0.000
D12.8 Rectum
0.590 0.410 0.000
D12.9 Anus and anal canal
0.589 0.410 0.000
D12.7 Rectosigmoid junction
0.589 0.410 0.000
D12.1 Appendix
0.589 0.410 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.587 0.413 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.587 0.413 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.586 0.413 0.000
H05 Disorders of orbit
0.586 0.413 0.000
H04 Disorders of lachrymal system
0.586 0.413 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.586 0.413 0.000
H01 Other inflammation of eyelid
0.586 0.413 0.000
H00 Hordeolum and chalazion
0.586 0.413 0.000
N92 Excessive, frequent and irregular menstruation
0.586 0.414 0.000
C34 Malignant neoplasm of bronchus and lung
0.586 0.414 0.000
H02.4 Ptosis of eyelid
0.585 0.414 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.584 0.416 0.000
H26.9 Cataract, unspecified
0.584 0.416 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.583 0.417 0.000
I73.0 Raynaud's syndrome
0.583 0.417 0.000
T81.9 Unspecified complication of procedure
0.582 0.417 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.582 0.417 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.582 0.417 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.582 0.417 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.582 0.417 0.000
Z51.0 Radiotherapy session
0.582 0.418 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.581 0.419 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.580 0.420 0.000
C95 Leukaemia of unspecified cell type
0.580 0.420 0.000
C94 Other leukaemias of specified cell type
0.580 0.420 0.000
C93 Monocytic leukaemia
0.580 0.420 0.000
C92 Myeloid leukaemia
0.580 0.420 0.000
C91 Lymphoid leukaemia
0.580 0.420 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.580 0.420 0.000
C88 Malignant immunoproliferative diseases
0.580 0.420 0.000
C86 Other specified types of T/NK-cell lymphoma
0.580 0.420 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.580 0.420 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.580 0.420 0.000
C81 Hodgkin's disease
0.580 0.420 0.000
J32 Chronic sinusitis
0.580 0.420 0.000
D12.6 Colon, unspecified
0.579 0.421 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.578 0.422 0.000
O70 Perineal laceration during delivery
0.578 0.422 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.577 0.423 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.576 0.423 0.000
H27 Other disorders of lens
0.576 0.423 0.000
N93 Other abnormal uterine and vaginal bleeding
0.576 0.424 0.000
I25.1 Atherosclerotic heart disease
0.575 0.425 0.000
D12.0 Caecum
0.574 0.426 0.000
I25.2 Old myocardial infarction
0.574 0.426 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.573 0.427 0.000
F99-F99 Unspecified mental disorder
0.572 0.428 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.572 0.428 0.000
F80-F89 Disorders of psychological development
0.572 0.428 0.000
F70-F79 Mental retardation
0.572 0.428 0.000
F60-F69 Disorders of adult personality and behaviour
0.572 0.428 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.572 0.428 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.572 0.428 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.572 0.428 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.572 0.428 0.000
C53 Malignant neoplasm of cervix uteri
0.572 0.428 0.000
C51 Malignant neoplasm of vulva
0.572 0.428 0.000
C58 Malignant neoplasm of placenta
0.572 0.428 0.000
C56 Malignant neoplasm of ovary
0.572 0.428 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.572 0.428 0.000
C52 Malignant neoplasm of vagina
0.572 0.428 0.000
C54.1 Endometrium
0.572 0.428 0.000
J34 Other disorders of nose and nasal sinuses
0.570 0.430 0.000
Y95 Nosocomial condition
0.568 0.432 0.000
D25.2 Subserosal leiomyoma of uterus
0.568 0.432 0.000
D25.0 Submucous leiomyoma of uterus
0.568 0.432 0.000
N20-N23 Urolithiasis
0.568 0.432 0.000
L50-L54 Urticaria and erythema
0.567 0.433 0.000
L40-L45 Papulosquamous disorders
0.567 0.433 0.000
L10-L14 Bullous disorders
0.567 0.433 0.000
S01.0 Open wound of scalp
0.567 0.433 0.000
T51 Toxic effect of alcohol
0.567 0.433 0.000
J21 Acute bronchiolitis
0.566 0.434 0.000
J20 Acute bronchitis
0.566 0.434 0.000
J98.1 Pulmonary collapse
0.566 0.434 0.000
B99-B99 Other infectious diseases
0.566 0.434 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.566 0.434 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.566 0.434 0.000
B65-B83 Helminthiases
0.566 0.434 0.000
B50-B64 Protozoal diseases
0.566 0.434 0.000
B25-B34 Other viral diseases
0.566 0.434 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.566 0.434 0.000
B15-B19 Viral hepatitis
0.566 0.434 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.566 0.434 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.566 0.434 0.000
A80-A89 Viral infections of the central nervous system
0.566 0.434 0.000
A75-A79 Rickettsioses
0.566 0.434 0.000
A70-A74 Other diseases caused by chlamydiae
0.566 0.434 0.000
A65-A69 Other spirochaetal diseases
0.566 0.434 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.566 0.434 0.000
A20-A28 Certain zoonotic bacterial diseases
0.566 0.434 0.000
A15-A19 Tuberculosis
0.566 0.434 0.000
I51 Complications and ill-defined descriptions of heart disease
0.565 0.435 0.000
D05 Carcinoma in situ of breast
0.564 0.436 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.564 0.436 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.564 0.436 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.561 0.438 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.561 0.438 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.561 0.438 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.561 0.438 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.561 0.438 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.561 0.438 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.561 0.438 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.561 0.438 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.561 0.438 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.561 0.438 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.561 0.438 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.561 0.438 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.561 0.438 0.000
T36 Poisoning by systemic antibiotics
0.561 0.438 0.000
Z54 Convalescence
0.561 0.439 0.000
Z52 Donors of organs and tissues
0.561 0.439 0.000
Z49 Care involving dialysis
0.561 0.439 0.000
Z44 Fitting and adjustment of external prosthetic device
0.561 0.439 0.000
Z43 Attention to artificial openings
0.561 0.439 0.000
Z42 Follow-up care involving plastic surgery
0.561 0.439 0.000
Z41 Procedures for purposes other than remedying health state
0.561 0.439 0.000
Z40 Prophylactic surgery
0.561 0.439 0.000
L60-L75 Disorders of skin appendages
0.561 0.439 0.000
I95 Hypotension
0.559 0.441 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.558 0.442 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.552 0.448 0.000
J90-J94 Other diseases of pleura
0.552 0.448 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.552 0.448 0.000
H25.9 Senile cataract, unspecified
0.551 0.449 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.550 0.450 0.000
S52 Fracture of forearm
0.550 0.450 0.000
T39.1 4-Aminophenol derivatives
0.549 0.451 0.000
N88 Other noninflammatory disorders of cervix uteri
0.548 0.452 0.000
A30-A49 Other bacterial diseases
0.547 0.452 0.000
Y83.9 Surgical procedure, unspecified
0.547 0.452 0.000
K70-K77 Diseases of liver
0.545 0.455 0.000
K35-K38 Diseases of appendix
0.545 0.455 0.000
N80 Endometriosis
0.545 0.455 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.545 0.455 0.000
I52 Other heart disorders in diseases classified elsewhere
0.545 0.455 0.000
I49 Other cardiac arrhythmias
0.545 0.455 0.000
I48 Atrial fibrillation and flutter
0.545 0.455 0.000
I46 Cardiac arrest
0.545 0.455 0.000
I45 Other conduction disorders
0.545 0.455 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.545 0.455 0.000
I42 Cardiomyopathy
0.545 0.455 0.000
I41 Myocarditis in diseases classified elsewhere
0.545 0.455 0.000
I40 Acute myocarditis
0.545 0.455 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.545 0.455 0.000
I37 Pulmonary valve disorders
0.545 0.455 0.000
I36 Nonrheumatic tricuspid valve disorders
0.545 0.455 0.000
I33 Acute and subacute endocarditis
0.545 0.455 0.000
I32 Pericarditis in diseases classified elsewhere
0.545 0.455 0.000
I30 Acute pericarditis
0.545 0.455 0.000
I38 Endocarditis, valve unspecified
0.545 0.455 0.000
K60 Fissure and fistula of anal and rectal regions
0.545 0.455 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.544 0.456 0.000
C83.3 Large cell (diffuse)
0.544 0.456 0.000
I84.1 Internal haemorrhoids with other complications
0.543 0.457 0.000
I25.6 Silent myocardial ischaemia
0.542 0.458 0.000
I25.5 Ischaemic cardiomyopathy
0.542 0.458 0.000
I25.4 Coronary artery aneurysm
0.542 0.458 0.000
I25.3 Aneurysm of heart
0.542 0.458 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.542 0.458 0.000
I44 Atrioventricular and left bundle-branch block
0.542 0.458 0.000
O36 Maternal care for other known or suspected foetal problems
0.541 0.458 0.000
J69 Pneumonitis due to solids and liquids
0.541 0.459 0.000
E86 Volume depletion
0.541 0.459 0.000
N13 Obstructive and reflux uropathy
0.540 0.460 0.000
I73.9 Peripheral vascular disease, unspecified
0.539 0.461 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.538 0.461 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.538 0.461 0.000
C32 Malignant neoplasm of larynx
0.538 0.461 0.000
C31 Malignant neoplasm of accessory sinuses
0.538 0.461 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.538 0.461 0.000
C37 Malignant neoplasm of thymus
0.538 0.461 0.000
C33 Malignant neoplasm of trachea
0.538 0.461 0.000
Z45.8 Adjustment and management of other implanted devices
0.538 0.462 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.537 0.462 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.537 0.463 0.000
J09-J18 Influenza and pneumonia
0.536 0.463 0.000
E66.8 Other obesity
0.537 0.463 0.000
Z51.3 Blood transfusion without reported diagnosis
0.536 0.464 0.000
I69 Sequelae of cerebrovascular disease
0.535 0.465 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.535 0.465 0.000
I67 Other cerebrovascular diseases
0.535 0.465 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.535 0.465 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.535 0.465 0.000
I62 Other nontraumatic intracranial haemorrhage
0.535 0.465 0.000
I61 Intracerebral haemorrhage
0.535 0.465 0.000
I60 Subarachnoid haemorrhage
0.535 0.465 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.535 0.465 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.535 0.465 0.000
O48 Prolonged pregnancy
0.534 0.465 0.000
C77.3 Axillary and upper limb lymph nodes
0.534 0.466 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.534 0.466 0.000
J96 Respiratory failure, not elsewhere classified
0.534 0.466 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.534 0.466 0.000
H42 Glaucoma in diseases classified elsewhere
0.534 0.466 0.000
I34 Nonrheumatic mitral valve disorders
0.533 0.467 0.000
Z50 Care involving use of rehabilitation procedures
0.532 0.468 0.000
Z47 Other orthopaedic follow-up care
0.531 0.468 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.531 0.469 0.000
E83 Disorders of mineral metabolism
0.531 0.469 0.000
I35 Nonrheumatic aortic valve disorders
0.531 0.469 0.000
Z45.2 Adjustment and management of vascular access device
0.530 0.470 0.000
K59 Other functional intestinal disorders
0.530 0.470 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.530 0.470 0.000
D09 Carcinoma in situ of other and unspecified sites
0.529 0.470 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.529 0.470 0.000
D06 Carcinoma in situ of cervix uteri
0.529 0.470 0.000
D04 Carcinoma in situ of skin
0.529 0.470 0.000
D03 Melanoma in situ
0.529 0.470 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.529 0.470 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.529 0.470 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.529 0.470 0.000
T65 Toxic effect of other and unspecified substances
0.528 0.472 0.000
T63 Toxic effect of contact with venomous animals
0.528 0.472 0.000
T62 Toxic effect of other noxious substances eaten as food
0.528 0.472 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.528 0.472 0.000
T60 Toxic effect of pesticides
0.528 0.472 0.000
T59 Toxic effect of other gases, fumes and vapours
0.528 0.472 0.000
T57 Toxic effect of other inorganic substances
0.528 0.472 0.000
T56 Toxic effect of metals
0.528 0.472 0.000
T54 Toxic effect of corrosive substances
0.528 0.472 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.528 0.472 0.000
T52 Toxic effect of organic solvents
0.528 0.472 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.528 0.472 0.000
T58 Toxic effect of carbon monoxide
0.528 0.472 0.000
T55 Toxic effect of soaps and detergents
0.528 0.472 0.000
K65-K67 Diseases of peritoneum
0.527 0.473 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.527 0.473 0.000
I88 Nonspecific lymphadenitis
0.527 0.473 0.000
I87 Other disorders of veins
0.527 0.473 0.000
I86 Varicose veins of other sites
0.527 0.473 0.000
I85 Oesophageal varices
0.527 0.473 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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