TreeWAS – Variant ID: rs17650401

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I51 Complications and ill-defined descriptions of heart disease	0.000	0.019	0.981
I51.8 Other ill-defined heart diseases	0.000	0.019	0.981
I51.7 Cardiomegaly	0.000	0.021	0.979
I30-I52 Other forms of heart disease	0.000	0.033	0.967
I45 Other conduction disorders	0.000	0.055	0.945
I42 Cardiomyopathy	0.000	0.068	0.932
I45.1 Other and unspecified right bundle-branch block	0.000	0.074	0.926
I47 Paroxysmal tachycardia	0.000	0.077	0.923
I47.2 Ventricular tachycardia	0.000	0.094	0.906
I42.0 Dilated cardiomyopathy	0.000	0.103	0.897
I42.9 Cardiomyopathy, unspecified	0.000	0.192	0.808
I33 Acute and subacute endocarditis	0.000	0.203	0.797
I31 Other diseases of pericardium	0.000	0.208	0.792
I37 Pulmonary valve disorders	0.000	0.234	0.766
I45.3 Trifascicular block	0.000	0.246	0.754
I34 Nonrheumatic mitral valve disorders	0.000	0.250	0.750
I36 Nonrheumatic tricuspid valve disorders	0.000	0.278	0.722
I45.5 Other specified heart block	0.000	0.291	0.709
I34.0 Mitral (valve) insufficiency	0.000	0.293	0.707
I51.5 Myocardial degeneration	0.000	0.296	0.704
I51.4 Myocarditis, unspecified	0.000	0.296	0.704
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.296	0.704
I42.8 Other cardiomyopathies	0.000	0.299	0.701
I45.8 Other specified conduction disorders	0.000	0.303	0.697
I47.0 Reentry ventricular arrhythmia	0.000	0.305	0.695
I52 Other heart disorders in diseases classified elsewhere	0.000	0.307	0.693
I48 Atrial fibrillation and flutter	0.000	0.307	0.693
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.307	0.693
I41 Myocarditis in diseases classified elsewhere	0.000	0.307	0.693
I40 Acute myocarditis	0.000	0.307	0.693
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.307	0.693
I32 Pericarditis in diseases classified elsewhere	0.000	0.307	0.693
I31.3 Pericardial effusion (noninflammatory)	0.000	0.313	0.687
I45.0 Right fascicular block	0.000	0.322	0.678
I33.0 Acute and subacute infective endocarditis	0.000	0.325	0.675
I45.4 Nonspecific intraventricular block	0.000	0.329	0.671
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.332	0.668
I42.5 Other restrictive cardiomyopathy	0.000	0.332	0.668
I42.4 Endocardial fibroelastosis	0.000	0.332	0.668
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.332	0.668
I45.2 Bifascicular block	0.000	0.341	0.658
I45.6 Preexcitation syndrome	0.000	0.343	0.656
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.344	0.656
I51.0 Cardiac septal defect, acquired	0.000	0.345	0.655
I45.9 Conduction disorder, unspecified	0.000	0.370	0.630
I42.2 Other hypertrophic cardiomyopathy	0.000	0.374	0.626
I37.1 Pulmonary valve insufficiency	0.000	0.379	0.621
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.380	0.620
I51.6 Cardiovascular disease, unspecified	0.000	0.396	0.604
I42.6 Alcoholic cardiomyopathy	0.000	0.402	0.598
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.402	0.597
I44 Atrioventricular and left bundle-branch block	0.000	0.411	0.589
I38 Endocarditis, valve unspecified	0.000	0.427	0.573
I33.9 Acute endocarditis, unspecified	0.000	0.428	0.571
I31.8 Other specified diseases of pericardium	0.000	0.432	0.568
I31.2 Haemopericardium, not elsewhere classified	0.000	0.432	0.568
I31.1 Chronic constrictive pericarditis	0.000	0.432	0.568
I31.0 Chronic adhesive pericarditis	0.000	0.432	0.568
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.440	0.559
I37.9 Pulmonary valve disorder, unspecified	0.000	0.451	0.549
I37.8 Other pulmonary valve disorders	0.000	0.451	0.549
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.451	0.549
I37.0 Pulmonary valve stenosis	0.000	0.451	0.549
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.454	0.546
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.462	0.537
I31.9 Disease of pericardium, unspecified	0.000	0.474	0.526
I47.1 Supraventricular tachycardia	0.000	0.476	0.524
I49 Other cardiac arrhythmias	0.000	0.477	0.523
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.482	0.517
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.482	0.517
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.482	0.517
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.482	0.517
I50 Heart failure	0.000	0.496	0.504
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.503	0.497
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.503	0.497
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.503	0.497
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.503	0.497
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.503	0.497
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.503	0.497
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.503	0.497
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.503	0.497
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.503	0.497
I40.9 Acute myocarditis, unspecified	0.000	0.503	0.497
I40.8 Other acute myocarditis	0.000	0.503	0.497
I40.1 Isolated myocarditis	0.000	0.503	0.497
I40.0 Infective myocarditis	0.000	0.503	0.497
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.503	0.497
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.503	0.497
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.503	0.497
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.503	0.497
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.503	0.497
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.503	0.497
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.503	0.497
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.503	0.497
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.503	0.497
I48.4 Atypical atrial flutter	0.000	0.503	0.497
I48.3 Typical atrial flutter	0.000	0.503	0.497
I48.2 Chronic atrial fibrillation	0.000	0.503	0.497
I48.1 Persistent atrial fibrillation	0.000	0.503	0.497
I48.0 Paroxysmal atrial fibrillation	0.000	0.503	0.497
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.503	0.497
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.503	0.497
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.503	0.497
I35 Nonrheumatic aortic valve disorders	0.000	0.504	0.496
I30 Acute pericarditis	0.001	0.517	0.482
I44.1 Atrioventricular block, second degree	0.000	0.525	0.475
I51.9 Heart disease, unspecified	0.000	0.531	0.469
I49.1 Atrial premature depolarisation	0.000	0.535	0.465
I44.0 Atrioventricular block, first degree	0.000	0.539	0.461
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.542	0.458
I44.2 Atrioventricular block, complete	0.000	0.542	0.458
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.564	0.435
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.572	0.427
I44.5 Left posterior fascicular block	0.000	0.578	0.422
I44.4 Left anterior fascicular block	0.000	0.578	0.422
I49.0 Ventricular fibrillation and flutter	0.000	0.600	0.400
I44.3 Other and unspecified atrioventricular block	0.000	0.611	0.389
I44.6 Other and unspecified fascicular block	0.000	0.612	0.388
I49.4 Other and unspecified premature depolarisation	0.000	0.612	0.387
I34.1 Mitral (valve) prolapse	0.000	0.622	0.378
I49.2 Junctional premature depolarisation	0.000	0.625	0.375
I49.3 Ventricular premature depolarisation	0.000	0.626	0.374
I50.1 Left ventricular failure	0.000	0.627	0.373
I35.9 Aortic valve disorder, unspecified	0.000	0.638	0.362
I30.8 Other forms of acute pericarditis	0.001	0.654	0.346
I30.0 Acute nonspecific idiopathic pericarditis	0.001	0.654	0.346
I46 Cardiac arrest	0.001	0.657	0.342
I50.0 Congestive heart failure	0.000	0.666	0.334
I35.8 Other aortic valve disorders	0.000	0.670	0.330
I49.9 Cardiac arrhythmia, unspecified	0.000	0.710	0.290
I49.5 Sick sinus syndrome	0.000	0.722	0.278
I30.1 Infective pericarditis	0.001	0.733	0.267
I30.9 Acute pericarditis, unspecified	0.001	0.737	0.262
I46.1 Sudden cardiac death, so described	0.001	0.754	0.245
I50.9 Heart failure, unspecified	0.000	0.799	0.201
I08 Multiple valve diseases	0.000	0.802	0.198
I05-I09 Chronic rheumatic heart diseases	0.000	0.804	0.196
I35.1 Aortic (valve) insufficiency	0.000	0.805	0.194
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.805	0.195
Chapter IX Diseases of the circulatory system	0.000	0.808	0.192
I46.9 Cardiac arrest, unspecified	0.001	0.817	0.182
I35.0 Aortic (valve) stenosis	0.000	0.823	0.177
I60-I69 Cerebrovascular diseases	0.000	0.830	0.170
I07 Rheumatic tricuspid valve diseases	0.000	0.836	0.163
I08.0 Disorders of both mitral and aortic valves	0.000	0.840	0.160
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.000	0.840	0.160
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.843	0.157
I69 Sequelae of cerebrovascular disease	0.000	0.843	0.157
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.845	0.155
I67 Other cerebrovascular diseases	0.000	0.845	0.155
I69.3 Sequelae of cerebral infarction	0.000	0.848	0.152
I05 Rheumatic mitral valve diseases	0.000	0.853	0.147
I65.2 Occlusion and stenosis of carotid artery	0.000	0.856	0.144
I08.8 Other multiple valve diseases	0.000	0.857	0.143
I08.9 Multiple valve disease, unspecified	0.000	0.858	0.142
I09 Other rheumatic heart diseases	0.000	0.859	0.140
I06 Rheumatic aortic valve diseases	0.000	0.859	0.140
I07.1 Tricuspid insufficiency	0.000	0.860	0.140
I67.9 Cerebrovascular disease, unspecified	0.000	0.860	0.140
I00-I02 Acute rheumatic fever	0.000	0.862	0.138
I44.7 Left bundle-branch block, unspecified	0.000	0.863	0.137
I67.8 Other specified cerebrovascular diseases	0.000	0.864	0.136
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.871	0.129
I63 Cerebral infarction	0.000	0.875	0.125
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.878	0.122
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.878	0.122
I62 Other nontraumatic intracranial haemorrhage	0.000	0.878	0.122
I05.0 Mitral stenosis	0.000	0.882	0.118
I07.9 Tricuspid valve disease, unspecified	0.000	0.883	0.117
I07.8 Other tricuspid valve diseases	0.000	0.883	0.117
I07.2 Tricuspid stenosis with insufficiency	0.000	0.883	0.117
I07.0 Tricuspid stenosis	0.000	0.883	0.117
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.884	0.116
I49.8 Other specified cardiac arrhythmias	0.002	0.885	0.113
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.886	0.114
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.887	0.113
I05.1 Rheumatic mitral insufficiency	0.000	0.889	0.111
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.889	0.111
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.889	0.111
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.889	0.111
I65.1 Occlusion and stenosis of basilar artery	0.000	0.889	0.111
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.889	0.111
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.889	0.111
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.889	0.111
I67.5 Moyamoya disease	0.000	0.889	0.111
I67.4 Hypertensive encephalopathy	0.000	0.889	0.111
I67.3 Progressive vascular leukoencephalopathy	0.000	0.889	0.111
I05.8 Other mitral valve diseases	0.000	0.894	0.105
I05.2 Mitral stenosis with insufficiency	0.000	0.895	0.105
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.895	0.105
I63.9 Cerebral infarction, unspecified	0.000	0.895	0.105
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.899	0.101
I06.8 Other rheumatic aortic valve diseases	0.000	0.899	0.101
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.899	0.101
I06.1 Rheumatic aortic insufficiency	0.000	0.899	0.101
I06.0 Rheumatic aortic stenosis	0.000	0.899	0.101
I09.9 Rheumatic heart disease, unspecified	0.000	0.899	0.101
I09.8 Other specified rheumatic heart diseases	0.000	0.899	0.101
I09.2 Chronic rheumatic pericarditis	0.000	0.899	0.101
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.899	0.101
I09.0 Rheumatic myocarditis	0.000	0.899	0.101
I02 Rheumatic chorea	0.000	0.901	0.099
I01 Rheumatic fever with heart involvement	0.000	0.901	0.099
I00 Rheumatic fever without mention of heart involvement	0.000	0.901	0.099
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.902	0.098
I67.1 Cerebral aneurysm, nonruptured	0.000	0.903	0.097
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.903	0.097
I67.2 Cerebral atherosclerosis	0.000	0.909	0.091
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.910	0.090
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.910	0.090
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.910	0.090
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.910	0.090
I05.9 Mitral valve disease, unspecified	0.000	0.911	0.089
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.912	0.087
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.912	0.087
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.912	0.087
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.912	0.087
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.912	0.087
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.912	0.087
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.912	0.087
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.912	0.087
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.912	0.087
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.912	0.087
I68.0 Cerebral amyloid angiopathy	0.000	0.912	0.087
I62.1 Nontraumatic extradural haemorrhage	0.000	0.912	0.087
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.913	0.086
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.916	0.083
I20-I25 Ischaemic heart diseases	0.000	0.919	0.081
I63.8 Other cerebral infarction	0.000	0.919	0.081
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.920	0.080
I24 Other acute ischaemic heart diseases	0.000	0.922	0.078
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.925	0.075
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.925	0.075
S64.4 Injury of digital nerve of other finger	0.000	0.927	0.073
I46.0 Cardiac arrest with successful resuscitation	0.002	0.927	0.071
S61 Open wound of wrist and hand	0.000	0.927	0.073
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.929	0.071
I01.8 Other acute rheumatic heart disease	0.000	0.929	0.071
I01.2 Acute rheumatic myocarditis	0.000	0.929	0.071
I01.1 Acute rheumatic endocarditis	0.000	0.929	0.071
I01.0 Acute rheumatic pericarditis	0.000	0.929	0.071
I02.9 Rheumatic chorea without heart involvement	0.000	0.929	0.071
I02.0 Rheumatic chorea with heart involvement	0.000	0.929	0.071
S64 Injury of nerves at wrist and hand level	0.000	0.930	0.070
I22 Subsequent myocardial infarction	0.000	0.932	0.068
S61.8 Open wound of other parts of wrist and hand	0.000	0.932	0.068
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.932	0.068
S60-S69 Injuries to the wrist and hand	0.000	0.932	0.068
S61.1 Open wound of finger(s) with damage to nail	0.000	0.934	0.066
I28 Other diseases of pulmonary vessels	0.000	0.935	0.065
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.936	0.064
S61.0 Open wound of finger(s) without damage to nail	0.000	0.937	0.063
S60 Superficial injury of wrist and hand	0.000	0.939	0.061
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.939	0.061
I24.8 Other forms of acute ischaemic heart disease	0.000	0.940	0.060
S61.7 Multiple open wounds of wrist and hand	0.000	0.940	0.059
S61.9 Open wound of wrist and hand, part unspecified	0.000	0.941	0.059
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.941	0.059
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.941	0.059
I61 Intracerebral haemorrhage	0.000	0.942	0.058
I22.8 Subsequent myocardial infarction of other sites	0.000	0.943	0.057
I24.1 Dressler's syndrome	0.000	0.944	0.056
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.000	0.945	0.055
I23 Certain current complications following acute myocardial infarction	0.000	0.947	0.053
I27 Other pulmonary heart diseases	0.000	0.947	0.053
S60.9 Superficial injury of wrist and hand, unspecified	0.000	0.948	0.052
S60.8 Other superficial injuries of wrist and hand	0.000	0.948	0.052
S64.2 Injury of radial nerve at wrist and hand level	0.000	0.949	0.051
S64.1 Injury of median nerve at wrist and hand level	0.000	0.949	0.051
I60 Subarachnoid haemorrhage	0.000	0.949	0.050
S66 Injury of muscle and tendon at wrist and hand level	0.000	0.950	0.050
S64.9 Injury of unspecified nerve at wrist and hand level	0.000	0.950	0.050
S64.8 Injury of other nerves at wrist and hand level	0.000	0.950	0.050
S64.7 Injury of multiple nerves at wrist and hand level	0.000	0.950	0.050
S64.3 Injury of digital nerve of thumb	0.000	0.950	0.050
I99 Other and unspecified disorders of circulatory system	0.000	0.951	0.049
S65 Injury of blood vessels at wrist and hand level	0.000	0.951	0.049
S64.0 Injury of ulnar nerve at wrist and hand level	0.000	0.951	0.048
S69 Other and unspecified injuries of wrist and hand	0.000	0.952	0.048
S67 Crushing injury of wrist and hand	0.000	0.952	0.048
S63.6 Sprain and strain of finger(s)	0.000	0.953	0.047
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.953	0.047
I28.8 Other specified diseases of pulmonary vessels	0.000	0.953	0.047
I28.1 Aneurysm of pulmonary artery	0.000	0.953	0.047
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.953	0.047
I27.0 Primary pulmonary hypertension	0.000	0.953	0.047
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.954	0.045
S60.7 Multiple superficial injuries of wrist and hand	0.000	0.956	0.044
S60.1 Contusion of finger(s) with damage to nail	0.000	0.956	0.044
S60.0 Contusion of finger(s) without damage to nail	0.000	0.956	0.044
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.957	0.043
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.958	0.042
S60.2 Contusion of other parts of wrist and hand	0.000	0.958	0.042
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.958	0.042
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.958	0.042
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.958	0.042
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.000	0.958	0.042
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.000	0.959	0.041
I26 Pulmonary embolism	0.000	0.960	0.040
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.000	0.960	0.040
S63.1 Dislocation finger	0.000	0.960	0.039
S63.7 Sprain and strain of other and unspecified parts of hand	0.000	0.960	0.039
S63.5 Sprain and strain of wrist	0.000	0.960	0.039
S63.2 Multiple dislocations of fingers	0.000	0.960	0.039
S66.8 Injury of other muscles and tendons at wrist and hand level	0.000	0.961	0.039
I10-I15 Hypertensive diseases	0.000	0.961	0.039
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.961	0.039
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.962	0.038
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.962	0.038
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.962	0.038
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.962	0.038
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.962	0.038
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.962	0.038
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.962	0.038
I27.1 Kyphoscoliotic heart disease	0.000	0.962	0.038
I61.8 Other intracerebral haemorrhage	0.000	0.962	0.038
S63.0 Dislocation of wrist	0.000	0.962	0.038
I60.8 Other subarachnoid haemorrhage	0.000	0.962	0.038
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.000	0.962	0.038
S63.3 Traumatic rupture of ligament of wrist and carpus	0.000	0.963	0.037
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.963	0.036
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.963	0.036
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.963	0.036
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.963	0.036
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.963	0.036
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.963	0.036
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.964	0.036
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.000	0.964	0.036
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.000	0.964	0.036
S68 Traumatic amputation of wrist and hand	0.000	0.964	0.036
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.964	0.036
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.000	0.964	0.035
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.000	0.965	0.035
S65.8 Injury of other blood vessels at wrist and hand level	0.000	0.965	0.035
S65.7 Injury of multiple blood vessels at wrist and hand level	0.000	0.965	0.035
S65.5 Injury of blood vessel(s) of other finger	0.000	0.965	0.035
S65.4 Injury of blood vessel(s) of thumb	0.000	0.965	0.035
S65.3 Injury of deep palmar arch	0.000	0.965	0.035
S65.2 Injury of superficial palmar arch	0.000	0.965	0.035
S65.1 Injury of radial artery at wrist and hand level	0.000	0.965	0.035
S65.0 Injury of ulnar artery at wrist and hand level	0.000	0.965	0.035
S69.8 Other specified injuries of wrist and hand	0.000	0.965	0.034
S69.7 Multiple injuries of wrist and hand	0.000	0.965	0.034
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.000	0.965	0.034
I27.8 Other specified pulmonary heart diseases	0.000	0.966	0.034
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.966	0.034
S69.9 Unspecified injury of wrist and hand	0.000	0.966	0.034
S67.0 Crushing injury of thumb and other finger(s)	0.000	0.966	0.033
I23.8 Other current complications following acute myocardial infarction	0.000	0.967	0.033
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.000	0.967	0.032
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.968	0.032
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.968	0.032
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.968	0.032
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.969	0.031
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.969	0.031
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.969	0.031
I98.0 Cardiovascular syphilis	0.000	0.969	0.031
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.000	0.969	0.031
I27.2 Other secondary pulmonary hypertension	0.000	0.969	0.030
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.970	0.030
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.971	0.029
I78 Diseases of capillaries	0.000	0.971	0.029
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.000	0.971	0.028
I13 Hypertensive heart and renal disease	0.000	0.972	0.028
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.972	0.028
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.000	0.973	0.027
I78.1 Naevus, nonneoplastic	0.000	0.974	0.026
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.000	0.974	0.026
S68.8 Traumatic amputation of other parts of wrist and hand	0.000	0.974	0.026
S68.4 Traumatic amputation of hand at wrist level	0.000	0.974	0.026
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.000	0.974	0.026
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.000	0.974	0.026
S68.0 Traumatic amputation of thumb (complete)(partial)	0.000	0.974	0.025
I15 Secondary hypertension	0.000	0.975	0.025
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.001	0.975	0.024
I70 Atherosclerosis	0.000	0.976	0.024
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.977	0.023
I97.0 Postcardiotomy syndrome	0.000	0.977	0.023
I11 Hypertensive heart disease	0.000	0.977	0.023
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.977	0.023
I27.9 Pulmonary heart disease, unspecified	0.001	0.977	0.022
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.977	0.022
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.978	0.022
I78.9 Disease of capillaries, unspecified	0.000	0.979	0.021
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.979	0.020
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.979	0.020
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.979	0.020
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.979	0.020
I12 Hypertensive renal disease	0.000	0.979	0.020
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.980	0.020
S62 Fracture at wrist and hand level	0.000	0.980	0.020
I72 Other aneurysm	0.000	0.980	0.020
I78.8 Other diseases of capillaries	0.000	0.981	0.019
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.981	0.019
I70.0 Atherosclerosis of aorta	0.000	0.981	0.019
I15.9 Seconday hypertension, unspecified	0.000	0.981	0.018
I15.8 Other secondary hypertension	0.000	0.981	0.018
I15.2 Hypertension secondary to endocrine disorders	0.000	0.981	0.018
I15.0 Renovascular hypertension	0.000	0.981	0.018
I70.9 Generalised and unspecified atherosclerosis	0.000	0.982	0.017
I70.8 Atherosclerosis of other arteries	0.000	0.982	0.017
I60.9 Subarachnoid haemorrhage, unspecified	0.001	0.982	0.017
I74 Arterial embolism and thrombosis	0.000	0.983	0.017
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.983	0.017
I97.1 Other functional disturbances following cardiac surgery	0.001	0.983	0.016
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.984	0.016
I79.1 Aortitis in diseases classified elsewhere	0.000	0.984	0.016
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.984	0.016
S32.00 Fracture of lumbar vertebra (closed)	0.016	0.984	0.000
I15.1 Hypertension secondary to other renal disorders	0.000	0.984	0.015
I70.1 Atherosclerosis of renal artery	0.000	0.984	0.015
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.984	0.015
I72.0 Aneurysm of carotid artery	0.000	0.985	0.015
S62.4 Multiple fractures of metacarpal bones	0.000	0.985	0.015
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.985	0.015
I72.8 Aneurysm of other specified arteries	0.000	0.985	0.015
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.000	0.985	0.015
S62.5 Fracture of thumb	0.000	0.985	0.015
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.985	0.015
I72.9 Aneurysm of unspecified site	0.000	0.986	0.014
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.986	0.014
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.986	0.014
I72.2 Aneurysm of renal artery	0.000	0.986	0.014
I72.1 Aneurysm of artery of upper extremity	0.000	0.986	0.014
I20 Angina pectoris	0.000	0.986	0.014
S32.0 Fracture of lumbar vertebra	0.014	0.986	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.986	0.014
R04.0 Epistaxis	0.000	0.986	0.014
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.986	0.014
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.986	0.013
S62.0 Fracture of navicular [scaphoid] bone of hand	0.000	0.986	0.013
I12.9 Hypertensive renal disease without renal failure	0.000	0.987	0.013
S62.3 Fracture of other metacarpal bone	0.000	0.987	0.013
S62.1 Fracture of other carpal bone(s)	0.000	0.987	0.013
I77 Other disorders of arteries and arterioles	0.000	0.987	0.013
S32 Fracture of lumbar spine and pelvis	0.013	0.987	0.000
I72.3 Aneurysm of iliac artery	0.000	0.987	0.013
S62.7 Multiple fractures of fingers	0.000	0.987	0.013
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.987	0.013
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.987	0.013
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.987	0.013
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.987	0.013
S62.2 Fracture of first metacarpal bone	0.000	0.987	0.013
I74.5 Embolism and thrombosis of iliac artery	0.000	0.987	0.013
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.987	0.012
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.987	0.012
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.987	0.012
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.987	0.012
S32.4 Fracture of acetabulum	0.012	0.988	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.000	0.988	0.012
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.988	0.012
I74.8 Embolism and thrombosis of other arteries	0.000	0.988	0.012
S62.40 Multiple fractures of metacarpal bones (closed)	0.000	0.988	0.012
I11.9 Hypertensive heart disease without (congestive) heart failure	0.001	0.988	0.012
S32.40 Fracture of acetabulum (closed)	0.012	0.988	0.000
S62.51 Fracture of thumb (open)	0.000	0.988	0.012
I85 Oesophageal varices	0.000	0.988	0.012
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.988	0.011
S32.3 Fracture of ilium	0.011	0.988	0.000
I81 Portal vein thrombosis	0.000	0.989	0.011
S62.41 Multiple fractures of metacarpal bones (open)	0.000	0.989	0.011
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.011	0.989	0.000
I77.0 Arteriovenous fistula, acquired	0.000	0.989	0.010
S32.01 Fracture of lumbar vertebra (open)	0.010	0.990	0.000
S32.1 Fracture of sacrum	0.010	0.990	0.000
S32.30 Fracture of ilium (closed)	0.010	0.990	0.000
S32.5 Fracture of pubis	0.010	0.990	0.000
I88 Nonspecific lymphadenitis	0.000	0.990	0.010
I20.8 Other forms of angina pectoris	0.000	0.990	0.010
I87 Other disorders of veins	0.000	0.990	0.010
I77.6 Arteritis, unspecified	0.000	0.990	0.010
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.000	0.990	0.010
S62.31 Fracture of other metacarpal bone (open)	0.000	0.990	0.010
I72.4 Aneurysm of artery of lower extremity	0.000	0.990	0.010
I77.5 Necrosis of artery	0.000	0.990	0.010
I77.4 Coeliac artery compression syndrome	0.000	0.990	0.010
I77.3 Arterial fibromuscular dysplasia	0.000	0.990	0.010
I77.2 Rupture of artery	0.000	0.990	0.010
S62.11 Fracture of other carpal bone(s) (open)	0.000	0.990	0.009
S62.50 Fracture of thumb (closed)	0.000	0.990	0.010
I12.0 Hypertensive renal disease with renal failure	0.000	0.990	0.010
S32.2 Fracture of coccyx	0.010	0.990	0.000
S62.71 Multiple fractures of fingers (open)	0.000	0.990	0.009
I73 Other peripheral vascular diseases	0.000	0.990	0.010
I80 Phlebitis and thrombophlebitis	0.000	0.990	0.010
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.990	0.009
O72.1 Other immediate postpartum haemorrhage	0.000	0.990	0.010
S62.21 Fracture of first metacarpal bone (open)	0.000	0.990	0.009
I85.9 Oesophageal varices without bleeding	0.000	0.990	0.009
S32.7 Multiple fractures of lumbar spine and pelvis	0.009	0.991	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.009	0.991	0.000
S32.41 Fracture of acetabulum (open)	0.009	0.991	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.000	0.991	0.009
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.991	0.009
I85.0 Oesophageal varices with bleeding	0.000	0.991	0.009
I86 Varicose veins of other sites	0.000	0.991	0.009
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.991	0.009
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.991	0.009
I21 Acute myocardial infarction	0.000	0.991	0.009
S62.10 Fracture of other carpal bone(s) (closed)	0.000	0.991	0.008

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations