TreeWAS – Variant ID: rs1772408

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I12.0 Hypertensive renal disease with renal failure	0.000	0.693	0.307
I12 Hypertensive renal disease	0.000	0.897	0.103
I12.9 Hypertensive renal disease without renal failure	0.000	0.949	0.051
H74 Other disorders of middle ear and mastoid	0.024	0.976	0.000
H65-H75 Diseases of middle ear and mastoid	0.023	0.977	0.000
H73 Other disorders of tympanic membrane	0.022	0.978	0.000
H73.8 Other specified disorders of tympanic membrane	0.022	0.978	0.000
H69 Other disorders of Eustachian tube	0.022	0.978	0.000
I10-I15 Hypertensive diseases	0.000	0.978	0.022
H74.4 Polyp of middle ear	0.021	0.979	0.000
H74.0 Tympanosclerosis	0.021	0.979	0.000
H70 Mastoiditis and related conditions	0.021	0.979	0.000
H72 Perforation of tympanic membrane	0.021	0.979	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.020	0.980	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.019	0.981	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.019	0.981	0.000
H70.9 Mastoiditis, unspecified	0.019	0.981	0.000
H69.9 Eustachian tube disorder, unspecified	0.019	0.981	0.000
H72.8 Other perforations of tympanic membrane	0.019	0.981	0.000
H74.1 Adhesive middle ear disease	0.018	0.981	0.000
H69.8 Other specified disorders of Eustachian tube	0.018	0.981	0.000
I11 Hypertensive heart disease	0.000	0.982	0.018
H74.8 Other specified disorders of middle ear and mastoid	0.017	0.983	0.000
H72.2 Other marginal perforations of tympanic membrane	0.017	0.983	0.000
I13 Hypertensive heart and renal disease	0.000	0.983	0.017
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.017	0.983	0.000
H67 Otitis media in diseases classified elsewhere	0.017	0.983	0.000
H65 Nonsuppurative otitis media	0.017	0.983	0.000
H66 Suppurative and unspecified otitis media	0.017	0.983	0.000
H72.0 Central perforation of tympanic membrane	0.017	0.983	0.000
H68 Eustachian salpingitis and obstruction	0.016	0.984	0.000
H73.0 Acute myringitis	0.016	0.984	0.000
H69.0 Patulous Eustachian tube	0.016	0.984	0.000
H70.0 Acute mastoiditis	0.016	0.984	0.000
H70.8 Other mastoiditis and related conditions	0.016	0.984	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.015	0.985	0.000
H73.1 Chronic myringitis	0.015	0.985	0.000
H70.2 Petrositis	0.015	0.985	0.000
N19 Unspecified renal failure	0.000	0.985	0.015
H65.0 Acute serous otitis media	0.014	0.986	0.000
H65.2 Chronic serous otitis media	0.014	0.986	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.986	0.014
H72.1 Attic perforation of tympanic membrane	0.014	0.986	0.000
H66.9 Otitis media, unspecified	0.014	0.986	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.986	0.014
H70.1 Chronic mastoiditis	0.014	0.986	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.986	0.014
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.987	0.013
H65.4 Other chronic nonsuppurative otitis media	0.013	0.987	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.987	0.012
H67.8 Otitis media in other diseases classified elsewhere	0.012	0.987	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.012	0.987	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.012	0.987	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.012	0.987	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.012	0.987	0.000
H65.1 Other acute nonsuppurative otitis media	0.012	0.988	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.988	0.012
H66.4 Suppurative otitis media, unspecified	0.012	0.988	0.000
I15 Secondary hypertension	0.000	0.988	0.012
H66.0 Acute suppurative otitis media	0.012	0.988	0.000
D13.1 Stomach	0.000	0.988	0.012
H68.0 Eustachian salpingitis	0.012	0.988	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.012	0.988	0.000
H68.1 Obstruction of Eustachian tube	0.011	0.989	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.011	0.989	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.011	0.989	0.000
H66.3 Other chronic suppurative otitis media	0.010	0.990	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.010	0.990	0.000
N42.8 Other specified disorders of prostate	0.010	0.990	0.000
Z45.0 Adjustment and management of cardiac pacemaker	0.000	0.990	0.010
I15.9 Seconday hypertension, unspecified	0.000	0.991	0.009
I15.2 Hypertension secondary to endocrine disorders	0.000	0.991	0.008
I15.8 Other secondary hypertension	0.000	0.992	0.008
I15.0 Renovascular hypertension	0.000	0.992	0.008
I15.1 Hypertension secondary to other renal disorders	0.000	0.992	0.008
N42.2 Atrophy of prostate	0.008	0.992	0.000
N42 Other disorders of prostate	0.007	0.993	0.000
N05.9 Unspecified	0.000	0.993	0.007
T78.2 Anaphylactic shock, unspecified	0.000	0.993	0.007
R29.6 Tendency to fall, not elsewhere classified	0.000	0.993	0.007
N42.9 Disorder of prostate, unspecified	0.007	0.993	0.000
N05 Unspecified nephritic syndrome	0.000	0.993	0.007
C73 Malignant neoplasm of thyroid gland	0.000	0.994	0.006
H93 Other disorders of ear, not elsewhere classified	0.006	0.994	0.000
H93.9 Disorder of ear, unspecified	0.006	0.994	0.000
N05.2 Diffuse membranous glomerulonephritis	0.000	0.994	0.006
N05.8 Other	0.000	0.994	0.006
N42.3 Dysplasia of prostate	0.006	0.994	0.000
H71 Cholesteatoma of middle ear	0.006	0.994	0.000
Chapter VIII Diseases of the ear and mastoid process	0.006	0.994	0.000
H93.8 Other specified disorders of ear	0.006	0.994	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.006	0.994	0.000
H65.3 Chronic mucoid otitis media	0.006	0.994	0.000
N05.1 Focal and segmental glomerular lesions	0.000	0.994	0.005
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.995	0.005
H93.1 Tinnitus	0.005	0.995	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.005	0.995	0.000
H93.3 Disorders of acoustic nerve	0.005	0.995	0.000
H93.2 Other abnormal auditory perceptions	0.005	0.995	0.000
N17-N19 Renal failure	0.000	0.995	0.005
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.005	0.995	0.000
N18.0 End-stage renal disease	0.000	0.995	0.005
N05.6 Dense deposit disease	0.000	0.995	0.005
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.995	0.005
N05.0 Minor glomerular abnormality	0.000	0.995	0.005
N18.9 Chronic renal failure, unspecified	0.000	0.995	0.005
H93.0 Degenerative and vascular disorders of ear	0.005	0.995	0.000
N18 Chronic renal failure	0.000	0.995	0.005
M89.86 Other specified disorders of bone (Lower leg)	0.000	0.995	0.005
H60-H62 Diseases of external ear	0.005	0.995	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.995	0.005
H61.2 Impacted cerumen	0.005	0.995	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.000	0.995	0.004
N60.0 Solitary cyst of breast	0.000	0.995	0.005
G55.2 Nerve root and plexus compressions in spondylosis	0.005	0.995	0.000
I21.4 Acute subendocardial myocardial infarction	0.004	0.996	0.000
N42.1 Congestion and haemorrhage of prostate	0.004	0.996	0.000
H61 Other disorders of external ear	0.004	0.996	0.000
H90-H95 Other disorders of ear	0.004	0.996	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.000	0.996	0.004
E87.0 Hyperosmolality and hypernatraemia	0.004	0.996	0.000
N42.0 Calculus of prostate	0.004	0.996	0.000
C74 Malignant neoplasm of adrenal gland	0.000	0.996	0.004
N18.4 Chronic kidney disease, stage 4	0.000	0.996	0.004
N18.5 Chronic kidney disease, stage 5	0.000	0.996	0.004
M11.2 Other chondrocalcinosis	0.004	0.996	0.000
N18.2 Chronic kidney disease, stage 2	0.000	0.996	0.004
N18.1 Chronic kidney disease, stage 1	0.000	0.996	0.003
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.000	0.996	0.003
H61.0 Perichondritis of external ear	0.003	0.996	0.000
C74.9 Adrenal gland, unspecified	0.000	0.996	0.003
I34.0 Mitral (valve) insufficiency	0.000	0.996	0.004
M89.8 Other specified disorders of bone	0.000	0.997	0.003
N18.8 Other chronic renal failure	0.000	0.997	0.003
H62 Disorders of external ear in diseases classified elsewhere	0.003	0.997	0.000
C75 Malignant neoplasm of other endocrine glands and related structures	0.000	0.997	0.003
H94 Other disorders of ear in diseases classified elsewhere	0.003	0.997	0.000
H60 Otitis externa	0.003	0.997	0.000
H61.9 Disorder of external ear, unspecified	0.003	0.997	0.000
H61.8 Other specified disorders of external ear	0.003	0.997	0.000
C74.1 Medulla of adrenal gland	0.000	0.997	0.003
M70.6 Trochanteric bursitis	0.003	0.997	0.000
C74.0 Cortex of adrenal gland	0.000	0.997	0.003
H60.0 Abscess of external ear	0.003	0.997	0.000
I51.8 Other ill-defined heart diseases	0.000	0.997	0.003
C75.9 Endocrine gland, unspecified	0.000	0.997	0.003
M11.27 Other chondrocalcinosis (Ankle and foot)	0.003	0.997	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.000	0.997	0.003
H61.1 Non-infective disorders of pinna	0.003	0.997	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.000	0.997	0.003
M89.89 Other specified disorders of bone (Site unspecified)	0.000	0.997	0.003
M11.29 Other chondrocalcinosis (Site unspecified)	0.003	0.997	0.000
M11.28 Other chondrocalcinosis (Other)	0.003	0.997	0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.003	0.997	0.000
M11.24 Other chondrocalcinosis (Hand)	0.003	0.997	0.000
M11.23 Other chondrocalcinosis (Forearm)	0.003	0.997	0.000
M11.22 Other chondrocalcinosis (Upper arm)	0.003	0.997	0.000
M11.21 Other chondrocalcinosis (Shoulder region)	0.003	0.997	0.000
M11.20 Other chondrocalcinosis (Multiple sites)	0.003	0.997	0.000
C75.0 Parathyroid gland	0.000	0.997	0.003
R21 Rash and other nonspecific skin eruption	0.000	0.997	0.003
G55.3 Nerve root and plexus compressions in other dorsopathies	0.003	0.997	0.000
H60.8 Other otitis externa	0.003	0.997	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.997	0.003
M70.69 Trochanteric bursitis-Site unspec	0.003	0.997	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.000	0.997	0.003
M89.80 Other specified disorders of bone (Multiple sites)	0.000	0.997	0.003
G61.0 Guillain-Barre syndrome	0.000	0.997	0.003
H60.9 Otitis externa, unspecified	0.003	0.997	0.000
M89.83 Other specified disorders of bone (Forearm)	0.000	0.997	0.003
H62.8 Other disorders of external ear in diseases classified elsewhere	0.002	0.997	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.002	0.997	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.002	0.997	0.000
H62.2 Otitis externa in mycoses	0.002	0.997	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.002	0.997	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.003	0.997	0.000
C75.8 Pluriglandular involvement, unspecified	0.000	0.997	0.003
C75.4 Carotid body	0.000	0.997	0.003
C75.3 Pineal gland	0.000	0.997	0.003
C75.2 Craniopharyngeal duct	0.000	0.997	0.003
H60.5 Acute otitis externa, non-infective	0.003	0.997	0.000
H61.3 Acquired stenosis of external ear canal	0.003	0.997	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.002	0.997	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.002	0.997	0.000
Q23.1 Congenital insufficiency of aortic valve	0.000	0.997	0.003
C67.9 Bladder, unspecified	0.003	0.997	0.000
C75.5 Aortic body and other paraganglia	0.000	0.997	0.002
M89.87 Other specified disorders of bone (Ankle and foot)	0.000	0.997	0.002
D13.6 Pancreas	0.000	0.997	0.003
M70.68 Trochanteric bursitis-Other	0.002	0.997	0.000
M70.67 Trochanteric bursitis-Ankle/Foot	0.002	0.997	0.000
M70.66 Trochanteric bursitis-Lower Leg	0.002	0.997	0.000
M70.64 Trochanteric bursitis-Hand	0.002	0.997	0.000
M70.63 Trochanteric bursitis-Forearm	0.002	0.997	0.000
M70.62 Trochanteric bursitis-Upper arm	0.002	0.997	0.000
M70.61 Trochanteric bursitis-Shldr region	0.002	0.997	0.000
M70.60 Trochanteric bursitis-Mult sites	0.002	0.997	0.000
R00.1 Bradycardia, unspecified	0.000	0.997	0.003
D13.3 Other and unspecified parts of small intestine	0.000	0.997	0.002
H60.2 Malignant otitis externa	0.002	0.997	0.000
H91 Other hearing loss	0.003	0.997	0.000
C75.1 Pituitary gland	0.000	0.997	0.002
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.002	0.998	0.000
H91.8 Other specified hearing loss	0.002	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.998	0.002
M89.84 Other specified disorders of bone (Hand)	0.000	0.998	0.002
Z49.1 Extracorporeal dialysis	0.000	0.998	0.002
M89.0 Algoneurodystrophy	0.000	0.998	0.002
I34 Nonrheumatic mitral valve disorders	0.000	0.998	0.002
H91.3 Deaf mutism, not elsewhere classified	0.002	0.998	0.000
M89.03 Algoneurodystrophy (Forearm)	0.000	0.998	0.002
C80.9 Malignant neoplasm, unspecified	0.000	0.998	0.002
L28.0 Lichen simplex chronicus	0.002	0.998	0.000
Z94.0 Kidney transplant status	0.000	0.998	0.002
H60.4 Cholesteatoma of external ear	0.002	0.998	0.000
H60.3 Other infective otitis externa	0.002	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.000	0.998	0.002
M89 Other disorders of bone	0.000	0.998	0.002
M48.07 Spinal stenosis (Lumbosacral region)	0.002	0.998	0.000
M89.04 Algoneurodystrophy (Hand)	0.000	0.998	0.002
D13.5 Extrahepatic bile ducts	0.000	0.998	0.002
Z30.5 Surveillance of (intra-uterine) contraceptive device	0.000	0.998	0.002
D13.7 Endocrine pancreas	0.000	0.998	0.002
H92 Otalgia and effusion of ear	0.002	0.998	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.002	0.998	0.000
R41.3 Other amnesia	0.002	0.998	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.002	0.998	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.002	0.998	0.000
C66 Malignant neoplasm of ureter	0.002	0.998	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.000	0.998	0.002
G55.0 Nerve root and plexus compressions in neoplastic disease	0.002	0.998	0.000
Q23.0 Congenital stenosis of aortic valve	0.000	0.998	0.002
C67.2 Lateral wall of bladder	0.002	0.998	0.000
D13.9 Ill-defined sites within the digestive system	0.000	0.998	0.002
G47.1 Disorders of excessive somnolence [hypersomnias]	0.002	0.998	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.998	0.002
Z73.3 Stress, not elsewhere classified	0.000	0.998	0.002
M79.11 Myalgia (Shoulder region)	0.000	0.998	0.002
N30.8 Other cystitis	0.002	0.998	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.002	0.998	0.000
D13.2 Duodenum	0.000	0.998	0.002
Q23.3 Congenital mitral insufficiency	0.000	0.998	0.002
Z49.2 Other dialysis	0.000	0.998	0.002
D10.1 Tongue	0.000	0.998	0.002
M89.4 Other hypertrophic osteo-arthropathy	0.000	0.998	0.002
M89.88 Other specified disorders of bone (Other)	0.001	0.998	0.002
H91.0 Ototoxic hearing loss	0.002	0.998	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.000	0.998	0.002
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.998	0.002
M89.06 Algoneurodystrophy (Lower leg)	0.000	0.998	0.002
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
M89.08 Algoneurodystrophy (Other)	0.000	0.998	0.002
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.000	0.998	0.002
M89.02 Algoneurodystrophy (Upper arm)	0.000	0.998	0.002
M89.00 Algoneurodystrophy (Multiple sites)	0.000	0.998	0.002
I44.0 Atrioventricular block, first degree	0.000	0.998	0.002
C67 Malignant neoplasm of bladder	0.002	0.998	0.000
C64-C68 Malignant neoplasms of urinary tract	0.002	0.998	0.000
M79.19 Myalgia (Site unspecified)	0.000	0.998	0.002
H95.1 Other disorders following mastoidectomy	0.002	0.998	0.000
M89.5 Osteolysis	0.000	0.998	0.002
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
C22.0 Liver cell carcinoma	0.000	0.998	0.002
D13.0 Oesophagus	0.000	0.998	0.002
M89.09 Algoneurodystrophy (Site unspecified)	0.000	0.998	0.002
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.002	0.998	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.000	0.998	0.002
H91.2 Sudden idiopathic hearing loss	0.002	0.998	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.000	0.998	0.002
Q23.8 Other congenital malformations of aortic and mitral valves	0.000	0.998	0.002
Q23.4 Hypoplastic left heart syndrome	0.000	0.998	0.002
Q23.2 Congenital mitral stenosis	0.000	0.998	0.002
M89.6 Osteopathy after poliomyelitis	0.000	0.998	0.002
M89.2 Other disorders of bone development and growth	0.000	0.998	0.002
M89.1 Epiphyseal arrest	0.000	0.998	0.002
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.000	0.998	0.002
C65 Malignant neoplasm of renal pelvis	0.002	0.998	0.000
Z49 Care involving dialysis	0.000	0.998	0.002
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
D13.4 Liver	0.000	0.998	0.002
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.000	0.998	0.002
Z49.0 Preparatory care for dialysis	0.000	0.998	0.002
C51.9 Vulva, unspecified	0.000	0.998	0.002
S89.9 Unspecified injury of lower leg	0.000	0.998	0.002
M89.55 Osteolysis (Pelvic region and thigh)	0.000	0.998	0.002
H92.2 Otorrhagia	0.002	0.998	0.000
C67.5 Bladder neck	0.002	0.998	0.000
M25.84 Other specified joint disorders (Hand)	0.002	0.998	0.000
M88.9 Paget's disease of bone, unspecified	0.000	0.998	0.002
Q27.3 Peripheral arteriovenous malformation	0.000	0.998	0.002
M79.1 Myalgia	0.000	0.998	0.002
Q28.0 Arteriovenous malformation of precerebral vessels	0.000	0.998	0.002
G70.0 Myasthenia gravis	0.002	0.998	0.000
H60.1 Cellulitis of external ear	0.002	0.998	0.000
H91.1 Presbycusis	0.002	0.998	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.000	0.998	0.002
C68 Malignant neoplasm of other and unspecified urinary organs	0.002	0.998	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.000	0.998	0.002
M89.48 Other hypertrophic osteoarthropathy (Other)	0.000	0.998	0.002
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.000	0.998	0.002
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.000	0.998	0.002
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.000	0.998	0.002
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.000	0.998	0.002
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.000	0.998	0.002
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.000	0.998	0.002
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.000	0.998	0.002
Q27 Other congenital malformations of peripheral vascular system	0.000	0.998	0.002
C67.8 Overlapping lesion of bladder	0.002	0.998	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.998	0.002
C67.7 Urachus	0.002	0.998	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.998	0.002
M89.59 Osteolysis (Site unspecified)	0.000	0.998	0.001
M89.58 Osteolysis (Other)	0.000	0.998	0.001
M89.57 Osteolysis (Ankle and foot)	0.000	0.998	0.001
M89.54 Osteolysis (Hand)	0.000	0.998	0.001
M89.53 Osteolysis (Forearm)	0.000	0.998	0.001
M89.52 Osteolysis (Upper arm)	0.000	0.998	0.001
M89.51 Osteolysis (Shoulder region)	0.000	0.998	0.001
M89.50 Osteolysis (Multiple sites)	0.000	0.998	0.001
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.998	0.002
J35.0 Chronic tonsillitis	0.002	0.998	0.000
M79.15 Myalgia (Pelvic region and thigh)	0.000	0.998	0.002
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.000	0.998	0.002
K11.8 Other diseases of salivary glands	0.002	0.998	0.000
K11.5 Sialolithiasis	0.002	0.998	0.000
M89.3 Hypertrophy of bone	0.000	0.998	0.001
R59.0 Localised enlarged lymph nodes	0.002	0.998	0.000
H80-H83 Diseases of inner ear	0.002	0.998	0.000
M79.18 Myalgia (Other)	0.000	0.998	0.002
M89.19 Epiphyseal arrest (Site unspecified)	0.000	0.998	0.001
M89.18 Epiphyseal arrest (Other)	0.000	0.998	0.001
M89.17 Epiphyseal arrest (Ankle and foot)	0.000	0.998	0.001
M89.16 Epiphyseal arrest (Lower leg)	0.000	0.998	0.001
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.000	0.998	0.001
M89.14 Epiphyseal arrest (Hand)	0.000	0.998	0.001
M89.13 Epiphyseal arrest (Forearm)	0.000	0.998	0.001
M89.12 Epiphyseal arrest (Upper arm)	0.000	0.998	0.001
M89.11 Epiphyseal arrest (Shoulder region)	0.000	0.998	0.001
M89.10 Epiphyseal arrest (Multiple sites)	0.000	0.998	0.001
M89.29 Other disorders of bone development and growth (Site unspecified)	0.000	0.998	0.001
M89.28 Other disorders of bone development and growth (Other)	0.000	0.998	0.001
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.000	0.998	0.001
M89.26 Other disorders of bone development and growth (Lower leg)	0.000	0.998	0.001
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.000	0.998	0.001
M89.24 Other disorders of bone development and growth (Hand)	0.000	0.998	0.001
M89.23 Other disorders of bone development and growth (Forearm)	0.000	0.998	0.001
M89.22 Other disorders of bone development and growth (Upper arm)	0.000	0.998	0.001
M89.21 Other disorders of bone development and growth (Shoulder region)	0.000	0.998	0.001
M89.20 Other disorders of bone development and growth (Multiple sites)	0.000	0.998	0.001
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.000	0.998	0.001
M89.68 Osteopathy after poliomyelitis (Other)	0.000	0.998	0.001
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.000	0.998	0.001
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.000	0.998	0.001
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.000	0.998	0.001
M89.64 Osteopathy after poliomyelitis (Hand)	0.000	0.998	0.001
M89.63 Osteopathy after poliomyelitis (Forearm)	0.000	0.998	0.001
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.000	0.998	0.001
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.000	0.998	0.001
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.000	0.998	0.001
C68.9 Urinary organ, unspecified	0.001	0.998	0.000
D89.3 Immune reconstitution syndrome	0.001	0.998	0.000
Q28 Other congenital malformations of circulatory system	0.000	0.998	0.002
C67.3 Anterior wall of bladder	0.002	0.998	0.000
C67.1 Dome of bladder	0.002	0.998	0.000
M88 Paget's disease of bone [osteitis deformans]	0.000	0.998	0.002
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.998	0.002
J38.0 Paralysis of vocal cords and larynx	0.000	0.998	0.002
Q20-Q28 Congenital malformations of the circulatory system	0.000	0.998	0.002
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.000	0.998	0.001
M89.56 Osteolysis (Lower leg)	0.000	0.998	0.001
K82.4 Cholesterolosis of gallbladder	0.000	0.998	0.002
M20.3 Other deformity of hallux (acquired)	0.000	0.998	0.002
M79.16 Myalgia (Lower leg)	0.000	0.998	0.001
M88.98 Paget's disease of bone, unspecified (Other)	0.000	0.998	0.001
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.000	0.998	0.001
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.000	0.998	0.001
M88.94 Paget's disease of bone, unspecified (Hand)	0.000	0.998	0.001
M88.93 Paget's disease of bone, unspecified (Forearm)	0.000	0.998	0.001
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.000	0.998	0.001
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.000	0.998	0.001
D89.9 Disorder involving the immune mechanism, unspecified	0.001	0.998	0.000
K11.7 Disturbances of salivary secretion	0.002	0.998	0.000
Q24.4 Congenital subaortic stenosis	0.000	0.998	0.001
M11 Other crystal arthropathies	0.002	0.998	0.000
Q24 Other congenital malformations of heart	0.000	0.998	0.002
M79.17 Myalgia (Ankle and foot)	0.000	0.998	0.001
M79.14 Myalgia (Hand)	0.000	0.998	0.001
M79.13 Myalgia (Forearm)	0.000	0.998	0.001
M79.12 Myalgia (Upper arm)	0.000	0.998	0.001
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.001	0.998	0.000
Q27.1 Congenital renal artery stenosis	0.000	0.998	0.001
S82.30 Fracture of lower end of tibia (closed)	0.000	0.998	0.002
C68.8 Overlapping lesion of urinary organs	0.001	0.998	0.000
C68.1 Paraurethral glands	0.001	0.998	0.000
D40.1 Testis	0.000	0.998	0.002
E04.9 Non-toxic goitre, unspecified	0.000	0.998	0.002
Q27.4 Congenital phlebectasia	0.000	0.998	0.001
Q27.2 Other congenital malformations of renal artery	0.000	0.998	0.001
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.000	0.998	0.001
D89.1 Cryoglobulinaemia	0.001	0.998	0.000
S82.60 Fracture of lateral malleolus (closed)	0.002	0.998	0.000
C68.0 Urethra	0.001	0.998	0.000
L57.0 Actinic keratosis	0.002	0.998	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.000	0.998	0.001
Q24.0 Dextrocardia	0.000	0.998	0.001
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.000	0.998	0.001
K11 Diseases of salivary glands	0.002	0.998	0.000
K37 Unspecified appendicitis	0.002	0.998	0.000
M89.39 Hypertrophy of bone (Site unspecified)	0.000	0.999	0.001
M89.36 Hypertrophy of bone (Lower leg)	0.000	0.999	0.001
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.000	0.999	0.001
M89.34 Hypertrophy of bone (Hand)	0.000	0.999	0.001
M89.33 Hypertrophy of bone (Forearm)	0.000	0.999	0.001
M89.32 Hypertrophy of bone (Upper arm)	0.000	0.999	0.001
M89.31 Hypertrophy of bone (Shoulder region)	0.000	0.999	0.001
M89.30 Hypertrophy of bone (Multiple sites)	0.000	0.999	0.001
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.001	0.999	0.000
H92.1 Otorrhoea	0.001	0.999	0.000
M88.8 Paget's disease of other bones	0.000	0.999	0.001
H82 Vertiginous syndromes in diseases classified elsewhere	0.001	0.999	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.001	0.999	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.000	0.999	0.001
D89.0 Polyclonal hypergammaglobulinaemia	0.001	0.999	0.000
M88.0 Paget's disease of skull	0.000	0.999	0.001
Q24.6 Congenital heart block	0.000	0.999	0.001
Q28.9 Congenital malformation of circulatory system, unspecified	0.000	0.999	0.001
Q28.8 Other specified congenital malformations of circulatory system	0.000	0.999	0.001
Q28.3 Other malformations of cerebral vessels	0.000	0.999	0.001
Q28.1 Other malformations of precerebral vessels	0.000	0.999	0.001
N17 Acute renal failure	0.000	0.999	0.001
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.000	0.999	0.001
K11.3 Abscess of salivary gland	0.001	0.999	0.000
K11.1 Hypertrophy of salivary gland	0.001	0.999	0.000
K11.0 Atrophy of salivary gland	0.001	0.999	0.000
L50.9 Urticaria, unspecified	0.000	0.999	0.001
Q20 Congenital malformations of cardiac chambers and connexions	0.000	0.999	0.001
M89.38 Hypertrophy of bone (Other)	0.000	0.999	0.001
D41.0 Kidney	0.001	0.999	0.000
L89.1 Stage II decubitus ulcer	0.000	0.999	0.001
M11.9 Crystal arthropathy, unspecified	0.001	0.999	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.999	0.001
Q24.3 Pulmonary infundibular stenosis	0.000	0.999	0.001
Q24.2 Cor triatriatum	0.000	0.999	0.001
Q24.1 Levocardia	0.000	0.999	0.001
Q22 Congenital malformations of pulmonary and tricuspid valves	0.000	0.999	0.001
M86-M90 Other osteopathies	0.000	0.999	0.001
M71.16 Other infective bursitis (Lower leg)	0.001	0.999	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.999	0.001
D10.0 Lip	0.000	0.999	0.001
M11.1 Familial chondrocalcinosis	0.001	0.999	0.000
M11.0 Hydroxyapatite deposition disease	0.001	0.999	0.000
Q26 Congenital malformations of great veins	0.000	0.999	0.001
C67.6 Ureteric orifice	0.001	0.999	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.999	0.001
Q22.1 Congenital pulmonary valve stenosis	0.000	0.999	0.001
Q25 Congenital malformations of great arteries	0.000	0.999	0.001
Q25.7 Other congenital malformations of pulmonary artery	0.000	0.999	0.001
Q27.8 Other specified congenital malformations of peripheral vascular system	0.000	0.999	0.001
M70 Soft tissue disorders related to use, overuse and pressure	0.001	0.999	0.000
M79.46 Hypertrophy of (infrapatellar) fat pad (Lower leg)	0.000	0.999	0.001
M88.88 Paget's disease of other bones (Other)	0.000	0.999	0.001
C67.0 Trigone of bladder	0.001	0.999	0.000
M11.8 Other specified crystal arthropathies	0.001	0.999	0.000
N17.1 Acute renal failure with acute cortical necrosis	0.000	0.999	0.001
M88.00 Paget's disease of skull-Mult sites	0.000	0.999	0.001
M88.89 Paget's disease of other bones (Site unspecified)	0.000	0.999	0.001
M88.87 Paget's disease of other bones (Ankle and foot)	0.000	0.999	0.001
M88.86 Paget's disease of other bones (Lower leg)	0.000	0.999	0.001
M88.85 Paget's disease of other bones (Pelvic region and thigh)	0.000	0.999	0.001
M88.84 Paget's disease of other bones (Hand)	0.000	0.999	0.001
M88.83 Paget's disease of other bones (Forearm)	0.000	0.999	0.001
M88.82 Paget's disease of other bones (Upper arm)	0.000	0.999	0.001
M88.81 Paget's disease of other bones (Shoulder region)	0.000	0.999	0.001
M88.80 Paget's disease of other bones (Multiple sites)	0.000	0.999	0.001
K11.6 Mucocele of salivary gland	0.001	0.999	0.000
K11.4 Fistula of salivary gland	0.001	0.999	0.000
M70.4 Prepatellar bursitis	0.001	0.999	0.000
M25.50 Pain in joint (Multiple sites)	0.000	0.999	0.001
M70.46 Prepatellar bursitis-Lower Leg	0.001	0.999	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.000	0.999	0.001
M88.09 Paget's disease of skull-Site unspec	0.000	0.999	0.001
M88.08 Paget's disease of skull-Other	0.000	0.999	0.001
M88.07 Paget's disease of skull-Ankle/Foot	0.000	0.999	0.001
M88.06 Paget's disease of skull-Lower Leg	0.000	0.999	0.001
M88.05 Paget's disease of skull-Pelvic/Thigh	0.000	0.999	0.001
M88.04 Paget's disease of skull-Hand	0.000	0.999	0.001
M88.03 Paget's disease of skull-Forearm	0.000	0.999	0.001
M88.02 Paget's disease of skull-Upper arm	0.000	0.999	0.001
M88.01 Paget's disease of skull-Shldr region	0.000	0.999	0.001
G70.9 Myoneural disorder, unspecified	0.001	0.999	0.000
I34.1 Mitral (valve) prolapse	0.000	0.999	0.001
L53.0 Toxic erythema	0.000	0.999	0.001
M71.1 Other infective bursitis	0.001	0.999	0.000
N17.2 Acute renal failure with medullary necrosis	0.000	0.999	0.001
R57.0 Cardiogenic shock	0.001	0.999	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.000	0.999	0.001
M71.34 Other bursal cyst (Hand)	0.001	0.999	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.000	0.999	0.001
S32.40 Fracture of acetabulum (closed)	0.001	0.999	0.000
G70.8 Other specified myoneural disorders	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations