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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1776897
log Bayes Factor = 0.757666
Chromosome 6   position 34,195,011  (GRCh37) Explore rs1776897 on Ensembl!
Variant rs1776897 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I30-I52 Other forms of heart disease
0.000 0.269 0.731
I34 Nonrheumatic mitral valve disorders
0.000 0.270 0.730
I34.0 Mitral (valve) insufficiency
0.000 0.275 0.725
I49 Other cardiac arrhythmias
0.000 0.296 0.704
I45 Other conduction disorders
0.000 0.298 0.702
Chapter IX Diseases of the circulatory system
0.000 0.328 0.672
I34.1 Mitral (valve) prolapse
0.000 0.333 0.667
I49.5 Sick sinus syndrome
0.000 0.336 0.664
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.340 0.660
I10-I15 Hypertensive diseases
0.000 0.344 0.656
I10 Essential (primary) hypertension
0.000 0.348 0.652
I77 Other disorders of arteries and arterioles
0.000 0.369 0.631
I49.9 Cardiac arrhythmia, unspecified
0.000 0.378 0.622
I35 Nonrheumatic aortic valve disorders
0.000 0.384 0.616
I50 Heart failure
0.000 0.387 0.613
I77.6 Arteritis, unspecified
0.000 0.388 0.612
I71 Aortic aneurysm and dissection
0.000 0.392 0.608
I51 Complications and ill-defined descriptions of heart disease
0.000 0.397 0.603
I45.6 Preexcitation syndrome
0.000 0.406 0.594
I45.5 Other specified heart block
0.000 0.409 0.591
I50.0 Congestive heart failure
0.000 0.411 0.589
I49.1 Atrial premature depolarisation
0.000 0.415 0.585
I49.8 Other specified cardiac arrhythmias
0.000 0.419 0.581
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.424 0.576
I20-I25 Ischaemic heart diseases
0.000 0.425 0.575
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.428 0.572
I35.9 Aortic valve disorder, unspecified
0.000 0.431 0.569
I38 Endocarditis, valve unspecified
0.000 0.431 0.569
I45.9 Conduction disorder, unspecified
0.000 0.433 0.567
I77.1 Stricture of artery
0.000 0.436 0.564
I30 Acute pericarditis
0.000 0.438 0.562
I74 Arterial embolism and thrombosis
0.000 0.442 0.558
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.448 0.552
I13 Hypertensive heart and renal disease
0.000 0.459 0.541
I45.2 Bifascicular block
0.000 0.461 0.539
I45.1 Other and unspecified right bundle-branch block
0.000 0.463 0.537
I47 Paroxysmal tachycardia
0.000 0.464 0.536
I45.3 Trifascicular block
0.000 0.464 0.535
I36 Nonrheumatic tricuspid valve disorders
0.000 0.467 0.533
I45.4 Nonspecific intraventricular block
0.000 0.468 0.532
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.470 0.530
I45.0 Right fascicular block
0.000 0.470 0.530
I72 Other aneurysm
0.000 0.474 0.526
I52 Other heart disorders in diseases classified elsewhere
0.000 0.476 0.524
I48 Atrial fibrillation and flutter
0.000 0.476 0.524
I41 Myocarditis in diseases classified elsewhere
0.000 0.476 0.524
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.476 0.524
I32 Pericarditis in diseases classified elsewhere
0.000 0.476 0.524
I25 Chronic ischaemic heart disease
0.000 0.481 0.519
I40 Acute myocarditis
0.000 0.487 0.513
I70 Atherosclerosis
0.000 0.490 0.510
I49.0 Ventricular fibrillation and flutter
0.000 0.491 0.509
I11 Hypertensive heart disease
0.000 0.491 0.509
I25.1 Atherosclerotic heart disease
0.000 0.493 0.507
I49.2 Junctional premature depolarisation
0.000 0.495 0.504
I05-I09 Chronic rheumatic heart diseases
0.000 0.501 0.499
I37 Pulmonary valve disorders
0.000 0.502 0.497
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.503 0.497
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.506 0.494
I83 Varicose veins of lower extremities
0.000 0.507 0.493
I77.2 Rupture of artery
0.000 0.518 0.482
I51.8 Other ill-defined heart diseases
0.000 0.520 0.480
I74.8 Embolism and thrombosis of other arteries
0.000 0.522 0.478
I51.9 Heart disease, unspecified
0.000 0.523 0.477
I45.8 Other specified conduction disorders
0.000 0.526 0.474
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.528 0.472
I35.1 Aortic (valve) insufficiency
0.000 0.533 0.467
I00-I02 Acute rheumatic fever
0.000 0.534 0.466
I25.2 Old myocardial infarction
0.000 0.534 0.466
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.534 0.465
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.538 0.462
I71.0 Dissection of aorta [any part]
0.000 0.539 0.460
I24 Other acute ischaemic heart diseases
0.000 0.540 0.460
I51.6 Cardiovascular disease, unspecified
0.000 0.543 0.457
I72.3 Aneurysm of iliac artery
0.000 0.543 0.457
I77.0 Arteriovenous fistula, acquired
0.000 0.544 0.456
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.544 0.456
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.546 0.454
I77.5 Necrosis of artery
0.000 0.548 0.452
I77.4 Coeliac artery compression syndrome
0.000 0.548 0.452
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.548 0.451
I51.5 Myocardial degeneration
0.000 0.553 0.447
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.553 0.447
I30.9 Acute pericarditis, unspecified
0.000 0.559 0.441
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.564 0.436
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.564 0.436
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.567 0.433
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.567 0.432
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.569 0.431
I24.8 Other forms of acute ischaemic heart disease
0.000 0.572 0.428
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.573 0.427
I33 Acute and subacute endocarditis
0.000 0.578 0.422
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.579 0.421
I42 Cardiomyopathy
0.000 0.579 0.421
I77.3 Arterial fibromuscular dysplasia
0.000 0.581 0.419
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.581 0.419
I22 Subsequent myocardial infarction
0.000 0.581 0.419
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.584 0.416
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.587 0.413
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.587 0.413
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.588 0.412
I35.0 Aortic (valve) stenosis
0.000 0.588 0.412
I78 Diseases of capillaries
0.000 0.589 0.411
I30.1 Infective pericarditis
0.000 0.590 0.410
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.591 0.409
I88 Nonspecific lymphadenitis
0.000 0.592 0.408
I74.5 Embolism and thrombosis of iliac artery
0.000 0.595 0.404
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.597 0.403
I47.1 Supraventricular tachycardia
0.000 0.599 0.401
I49.4 Other and unspecified premature depolarisation
0.000 0.599 0.400
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.599 0.401
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.602 0.398
I30.8 Other forms of acute pericarditis
0.000 0.602 0.398
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.602 0.397
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.603 0.397
I23 Certain current complications following acute myocardial infarction
0.000 0.603 0.397
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.604 0.396
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.605 0.395
I72.8 Aneurysm of other specified arteries
0.000 0.606 0.394
I47.0 Reentry ventricular arrhythmia
0.000 0.607 0.393
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.608 0.392
I77.8 Other specified disorders of arteries and arterioles
0.000 0.608 0.392
I20 Angina pectoris
0.000 0.609 0.391
I15 Secondary hypertension
0.000 0.610 0.390
I72.1 Aneurysm of artery of upper extremity
0.000 0.612 0.388
I70.0 Atherosclerosis of aorta
0.000 0.612 0.388
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.612 0.388
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.613 0.387
I05 Rheumatic mitral valve diseases
0.000 0.616 0.384
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.617 0.382
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.617 0.382
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.617 0.382
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.617 0.382
I06 Rheumatic aortic valve diseases
0.000 0.619 0.381
I72.4 Aneurysm of artery of lower extremity
0.000 0.620 0.380
I70.1 Atherosclerosis of renal artery
0.000 0.620 0.380
I40.9 Acute myocarditis, unspecified
0.000 0.622 0.377
I44 Atrioventricular and left bundle-branch block
0.000 0.623 0.377
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.623 0.377
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.624 0.376
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.624 0.376
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.624 0.376
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.624 0.376
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.624 0.376
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.624 0.376
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.624 0.376
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.624 0.376
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.624 0.376
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.624 0.376
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.624 0.376
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.624 0.376
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.624 0.376
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.624 0.376
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.624 0.376
I48.4 Atypical atrial flutter
0.000 0.624 0.376
I48.3 Typical atrial flutter
0.000 0.624 0.376
I48.2 Chronic atrial fibrillation
0.000 0.624 0.376
I48.1 Persistent atrial fibrillation
0.000 0.624 0.376
I48.0 Paroxysmal atrial fibrillation
0.000 0.624 0.376
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.624 0.376
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.624 0.376
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.624 0.376
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.625 0.375
I25.6 Silent myocardial ischaemia
0.000 0.627 0.373
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.629 0.371
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.631 0.369
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.631 0.368
I40.8 Other acute myocarditis
0.000 0.632 0.368
I40.1 Isolated myocarditis
0.000 0.632 0.368
I87 Other disorders of veins
0.000 0.632 0.368
I37.0 Pulmonary valve stenosis
0.000 0.632 0.367
I81 Portal vein thrombosis
0.000 0.632 0.367
I51.4 Myocarditis, unspecified
0.000 0.638 0.362
I72.0 Aneurysm of carotid artery
0.000 0.640 0.360
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.641 0.359
I37.9 Pulmonary valve disorder, unspecified
0.000 0.643 0.357
I37.8 Other pulmonary valve disorders
0.000 0.643 0.357
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.643 0.357
I09 Other rheumatic heart diseases
0.000 0.643 0.356
I47.2 Ventricular tachycardia
0.000 0.644 0.356
I72.2 Aneurysm of renal artery
0.000 0.645 0.355
I70.9 Generalised and unspecified atherosclerosis
0.000 0.648 0.352
I20.0 Unstable angina
0.000 0.649 0.351
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.650 0.350
I25.5 Ischaemic cardiomyopathy
0.000 0.652 0.348
I70.8 Atherosclerosis of other arteries
0.000 0.653 0.347
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.653 0.347
I72.9 Aneurysm of unspecified site
0.000 0.653 0.346
I40.0 Infective myocarditis
0.000 0.654 0.346
I86 Varicose veins of other sites
0.000 0.657 0.343
I31 Other diseases of pericardium
0.000 0.659 0.341
I21 Acute myocardial infarction
0.000 0.660 0.340
I07 Rheumatic tricuspid valve diseases
0.000 0.660 0.340
I08 Multiple valve diseases
0.000 0.660 0.340
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.661 0.339
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.663 0.337
I44.7 Left bundle-branch block, unspecified
0.000 0.664 0.336
I02 Rheumatic chorea
0.000 0.666 0.334
I01 Rheumatic fever with heart involvement
0.000 0.666 0.334
I42.6 Alcoholic cardiomyopathy
0.000 0.666 0.334
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.671 0.329
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.672 0.328
I21.9 Acute myocardial infarction, unspecified
0.000 0.679 0.321
I51.7 Cardiomegaly
0.000 0.680 0.320
I24.1 Dressler's syndrome
0.000 0.680 0.320
I00 Rheumatic fever without mention of heart involvement
0.000 0.681 0.319
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.681 0.319
I51.0 Cardiac septal defect, acquired
0.000 0.682 0.318
I05.9 Mitral valve disease, unspecified
0.000 0.682 0.318
I37.1 Pulmonary valve insufficiency
0.000 0.683 0.317
I20.1 Angina pectoris with documented spasm
0.000 0.683 0.317
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.688 0.312
I73 Other peripheral vascular diseases
0.000 0.688 0.312
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.690 0.310
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.691 0.309
I15.8 Other secondary hypertension
0.000 0.694 0.306
I42.4 Endocardial fibroelastosis
0.000 0.695 0.305
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.698 0.302
I85 Oesophageal varices
0.000 0.699 0.301
I05.8 Other mitral valve diseases
0.000 0.699 0.301
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.700 0.300
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.700 0.300
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.703 0.297
I06.0 Rheumatic aortic stenosis
0.000 0.704 0.296
I42.5 Other restrictive cardiomyopathy
0.000 0.705 0.295
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.705 0.295
I50.9 Heart failure, unspecified
0.000 0.706 0.294
I08.0 Disorders of both mitral and aortic valves
0.000 0.707 0.293
I50.1 Left ventricular failure
0.000 0.710 0.290
I44.4 Left anterior fascicular block
0.000 0.710 0.290
I78.8 Other diseases of capillaries
0.000 0.711 0.289
I87.8 Other specified disorders of veins
0.000 0.712 0.288
I78.9 Disease of capillaries, unspecified
0.000 0.712 0.288
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.714 0.286
I42.8 Other cardiomyopathies
0.000 0.715 0.285
I79.1 Aortitis in diseases classified elsewhere
0.000 0.715 0.285
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.715 0.285
I25.4 Coronary artery aneurysm
0.000 0.715 0.284
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.715 0.284
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.715 0.284
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.715 0.284
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.715 0.284
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.715 0.284
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.715 0.284
I42.2 Other hypertrophic cardiomyopathy
0.000 0.716 0.284
I44.1 Atrioventricular block, second degree
0.000 0.717 0.283
I23.8 Other current complications following acute myocardial infarction
0.000 0.717 0.282
I05.0 Mitral stenosis
0.000 0.718 0.282
I15.9 Seconday hypertension, unspecified
0.000 0.720 0.279
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.721 0.278
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.722 0.278
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.722 0.278
I33.9 Acute endocarditis, unspecified
0.000 0.726 0.273
I22.8 Subsequent myocardial infarction of other sites
0.000 0.727 0.273
I06.8 Other rheumatic aortic valve diseases
0.000 0.727 0.273
I87.0 Postphlebitic syndrome
0.000 0.727 0.272
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.727 0.272
I15.0 Renovascular hypertension
0.000 0.728 0.272
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.728 0.272
I89.1 Lymphangitis
0.000 0.729 0.271
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.729 0.271
I44.5 Left posterior fascicular block
0.000 0.729 0.271
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.730 0.270
I35.8 Other aortic valve disorders
0.001 0.730 0.269
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.730 0.269
I06.1 Rheumatic aortic insufficiency
0.000 0.730 0.269
I87.9 Disorder of vein, unspecified
0.000 0.733 0.267
I44.2 Atrioventricular block, complete
0.000 0.735 0.265
I88.8 Other nonspecific lymphadenitis
0.000 0.736 0.264
I15.2 Hypertension secondary to endocrine disorders
0.000 0.738 0.261
I49.3 Ventricular premature depolarisation
0.000 0.739 0.260
I05.2 Mitral stenosis with insufficiency
0.000 0.743 0.257
I09.8 Other specified rheumatic heart diseases
0.000 0.744 0.256
I09.2 Chronic rheumatic pericarditis
0.000 0.744 0.256
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.744 0.256
I09.0 Rheumatic myocarditis
0.000 0.744 0.256
I87.1 Compression of vein
0.000 0.744 0.256
I09.9 Rheumatic heart disease, unspecified
0.000 0.746 0.254
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.747 0.253
I86.8 Varicose veins of other specified sites
0.000 0.750 0.250
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.751 0.249
I86.1 Scrotal varices
0.000 0.752 0.248
I08.9 Multiple valve disease, unspecified
0.000 0.752 0.248
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.752 0.248
I78.1 Naevus, nonneoplastic
0.000 0.753 0.247
I86.2 Pelvic varices
0.000 0.754 0.246
I86.0 Sublingual varices
0.000 0.754 0.246
I31.8 Other specified diseases of pericardium
0.000 0.755 0.245
I31.2 Haemopericardium, not elsewhere classified
0.000 0.755 0.245
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.756 0.244
I07.9 Tricuspid valve disease, unspecified
0.000 0.756 0.244
I07.8 Other tricuspid valve diseases
0.000 0.756 0.244
I07.2 Tricuspid stenosis with insufficiency
0.000 0.756 0.244
I07.0 Tricuspid stenosis
0.000 0.756 0.244
I31.1 Chronic constrictive pericarditis
0.000 0.756 0.244
I33.0 Acute and subacute infective endocarditis
0.000 0.756 0.243
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.757 0.243
I77.9 Disorder of arteries and arterioles, unspecified
0.001 0.759 0.241
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.760 0.240
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.760 0.240
I01.8 Other acute rheumatic heart disease
0.000 0.760 0.240
I01.2 Acute rheumatic myocarditis
0.000 0.760 0.240
I01.1 Acute rheumatic endocarditis
0.000 0.760 0.240
I01.0 Acute rheumatic pericarditis
0.000 0.760 0.240
I02.9 Rheumatic chorea without heart involvement
0.000 0.760 0.240
I02.0 Rheumatic chorea with heart involvement
0.000 0.760 0.240
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.761 0.239
I42.9 Cardiomyopathy, unspecified
0.000 0.761 0.239
I86.3 Vulval varices
0.000 0.761 0.239
I08.8 Other multiple valve diseases
0.000 0.761 0.239
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.764 0.236
I86.4 Gastric varices
0.000 0.765 0.235
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.766 0.234
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.767 0.232
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.770 0.230
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.773 0.227
I07.1 Tricuspid insufficiency
0.000 0.774 0.226
I46 Cardiac arrest
0.001 0.776 0.224
I05.1 Rheumatic mitral insufficiency
0.000 0.779 0.221
I31.0 Chronic adhesive pericarditis
0.000 0.784 0.215
I82 Other venous embolism and thrombosis
0.000 0.787 0.212
I85.9 Oesophageal varices without bleeding
0.000 0.788 0.211
I44.0 Atrioventricular block, first degree
0.000 0.789 0.211
I31.3 Pericardial effusion (noninflammatory)
0.000 0.793 0.207
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.002 0.800 0.198
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.802 0.198
I12 Hypertensive renal disease
0.000 0.802 0.198
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.803 0.196
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.805 0.195
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.805 0.195
I89.0 Lymphoedema, not elsewhere classified
0.000 0.807 0.193
I25.3 Aneurysm of heart
0.001 0.807 0.192
I15.1 Hypertension secondary to other renal disorders
0.001 0.809 0.191
I73.0 Raynaud's syndrome
0.000 0.809 0.191
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.810 0.190
I31.9 Disease of pericardium, unspecified
0.000 0.812 0.188
I20.8 Other forms of angina pectoris
0.000 0.813 0.187
I42.0 Dilated cardiomyopathy
0.000 0.814 0.186
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.816 0.184
I73.9 Peripheral vascular disease, unspecified
0.000 0.817 0.183
I73.8 Other specified peripheral vascular diseases
0.000 0.819 0.180
E21.0 Primary hyperparathyroidism
0.000 0.822 0.178
I21.4 Acute subendocardial myocardial infarction
0.000 0.830 0.170
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.832 0.168
I85.0 Oesophageal varices with bleeding
0.000 0.832 0.167
I44.3 Other and unspecified atrioventricular block
0.001 0.835 0.165
I46.1 Sudden cardiac death, so described
0.001 0.841 0.158
I82.0 Budd-Chiari syndrome
0.000 0.843 0.157
E21.3 Hyperparathyroidism, unspecified
0.000 0.844 0.156
N40 Hyperplasia of prostate
0.000 0.846 0.154
E20-E35 Disorders of other endocrine glands
0.000 0.846 0.154
I82.1 Thrombophlebitis migrans
0.000 0.847 0.152
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.850 0.149
I82.2 Embolism and thrombosis of vena cava
0.000 0.855 0.145
E27 Other disorders of adrenal gland
0.000 0.856 0.144
I28 Other diseases of pulmonary vessels
0.002 0.865 0.133
I82.3 Embolism and thrombosis of renal vein
0.000 0.868 0.132
E25 Adrenogenital disorders
0.000 0.873 0.127
E26 Hyperaldosteronism
0.000 0.873 0.127
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.873 0.127
E21.4 Other specified disorders of parathyroid gland
0.000 0.874 0.126
E24 Cushing's syndrome
0.000 0.875 0.125
I82.8 Embolism and thrombosis of other specified veins
0.000 0.878 0.122
E21.2 Other hyperparathyroidism
0.000 0.881 0.119
E28 Ovarian dysfunction
0.000 0.882 0.118
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.883 0.116
E27.8 Other specified disorders of adrenal gland
0.000 0.885 0.115
E31 Polyglandular dysfunction
0.000 0.887 0.113
E32 Diseases of thymus
0.000 0.888 0.112
E27.2 Addisonian crisis
0.000 0.888 0.112
E23 Hypofunction and other disorders of pituitary gland
0.000 0.889 0.111
E27.1 Primary adrenocortical insufficiency
0.000 0.889 0.111
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.890 0.110
E30 Disorders of puberty, not elsewhere classified
0.000 0.890 0.110
I44.6 Other and unspecified fascicular block
0.002 0.890 0.108
E20 Hypoparathyroidism
0.000 0.891 0.109
E27.9 Disorder of adrenal gland, unspecified
0.000 0.892 0.108
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.892 0.108
E26.0 Primary hyperaldosteronism
0.000 0.892 0.108
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.892 0.108
E28.3 Primary ovarian failure
0.000 0.895 0.105
E29 Testicular dysfunction
0.000 0.895 0.105
E24.9 Cushing's syndrome, unspecified
0.000 0.896 0.104
E27.5 Adrenomedullary hyperfunction
0.000 0.897 0.103
E27.0 Other adrenocortical overactivity
0.000 0.897 0.103
I28.0 Arteriovenous fistula of pulmonary vessels
0.001 0.900 0.098
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.902 0.098
I28.1 Aneurysm of pulmonary artery
0.001 0.903 0.096
E34 Other endocrine disorders
0.000 0.904 0.096
E22 Hyperfunction of pituitary gland
0.000 0.904 0.095
E24.2 Drug-induced Cushing's syndrome
0.000 0.905 0.095
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.905 0.094
E24.8 Other Cushing's syndrome
0.000 0.906 0.094
I20.9 Angina pectoris, unspecified
0.000 0.907 0.093
I28.9 Disease of pulmonary vessels, unspecified
0.001 0.908 0.090
I28.8 Other specified diseases of pulmonary vessels
0.001 0.908 0.090
E25.9 Adrenogenital disorder, unspecified
0.000 0.909 0.091
E25.8 Other adrenogenital disorders
0.000 0.909 0.091
E26.8 Other hyperaldosteronism
0.000 0.909 0.091
E26.1 Secondary hyperaldosteronism
0.000 0.909 0.091
I12.9 Hypertensive renal disease without renal failure
0.001 0.910 0.090
E26.9 Hyperaldosteronism, unspecified
0.000 0.910 0.090
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.910 0.090
E24.3 Ectopic ACTH syndrome
0.000 0.910 0.090
E24.1 Nelson's syndrome
0.000 0.910 0.090
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.911 0.089
I80 Phlebitis and thrombophlebitis
0.000 0.913 0.087
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.913 0.087
I99 Other and unspecified disorders of circulatory system
0.000 0.914 0.085
E28.9 Ovarian dysfunction, unspecified
0.000 0.915 0.085
E28.8 Other ovarian dysfunction
0.000 0.915 0.085
E28.1 Androgen excess
0.000 0.915 0.085
E28.0 Oestrogen excess
0.000 0.915 0.085
E23.7 Disorder of pituitary gland, unspecified
0.000 0.915 0.085
E31.0 Autoimmune polyglandular failure
0.000 0.915 0.084
E32.8 Other diseases of thymus
0.000 0.916 0.083
E31.9 Polyglandular dysfunction, unspecified
0.000 0.918 0.081
E31.8 Other polyglandular dysfunction
0.000 0.918 0.081
E31.1 Polyglandular hyperfunction
0.000 0.918 0.081
E20.8 Other hypoparathyroidism
0.000 0.919 0.081
I46.0 Cardiac arrest with successful resuscitation
0.001 0.919 0.080
E32.1 Abscess of thymus
0.000 0.919 0.081
E32.0 Persistent hyperplasia of thymus
0.000 0.919 0.081
E23.6 Other disorders of pituitary gland
0.000 0.919 0.081
E32.9 Disease of thymus, unspecified
0.000 0.920 0.080
E23.1 Drug-induced hypopituitarism
0.000 0.920 0.080
E23.0 Hypopituitarism
0.000 0.920 0.080
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.920 0.080
E30.9 Disorder of puberty, unspecified
0.000 0.921 0.079
E30.8 Other disorders of puberty
0.000 0.921 0.079
E30.1 Precocious puberty
0.000 0.921 0.079
E30.0 Delayed puberty
0.000 0.921 0.079
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.921 0.079
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.921 0.079
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.921 0.079
E20.0 Idiopathic hypoparathyroidism
0.000 0.921 0.078
E24.0 Pituitary-dependent Cushing's disease
0.000 0.922 0.078
E20.1 Pseudohypoparathyroidism
0.000 0.922 0.078
E29.9 Testicular dysfunction, unspecified
0.000 0.923 0.077
E23.2 Diabetes insipidus
0.000 0.924 0.076
E29.8 Other testicular dysfunction
0.000 0.924 0.075
E29.0 Testicular hyperfunction
0.000 0.924 0.075
E20.9 Hypoparathyroidism, unspecified
0.000 0.925 0.075
I26 Pulmonary embolism
0.002 0.925 0.073
E34.0 Carcinoid syndrome
0.000 0.926 0.074
E22.1 Hyperprolactinaemia
0.000 0.929 0.071
I46.9 Cardiac arrest, unspecified
0.001 0.930 0.069
E34.5 Androgen resistance syndrome
0.000 0.931 0.069
E34.4 Constitutional tall stature
0.000 0.931 0.069
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.931 0.069
E34.1 Other hypersecretion of intestinal hormones
0.000 0.931 0.069
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.931 0.069
E22.8 Other hyperfunction of pituitary gland
0.000 0.931 0.069
E29.1 Testicular hypofunction
0.000 0.932 0.068
I27 Other pulmonary heart diseases
0.003 0.932 0.065
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.933 0.067
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.933 0.067
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.935 0.065
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.936 0.064
E34.3 Short stature, not elsewhere classified
0.000 0.936 0.064
E22.0 Acromegaly and pituitary gigantism
0.000 0.937 0.063
I97.0 Postcardiotomy syndrome
0.000 0.937 0.063
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.937 0.062
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.937 0.062
I98.0 Cardiovascular syphilis
0.000 0.937 0.062
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.938 0.062
E34.9 Endocrine disorder, unspecified
0.000 0.938 0.062
E34.8 Other specified endocrine disorders
0.000 0.938 0.061
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.940 0.059
R00.1 Bradycardia, unspecified
0.000 0.943 0.057
I97.1 Other functional disturbances following cardiac surgery
0.000 0.944 0.056
E28.2 Polycystic ovarian syndrome
0.000 0.944 0.055
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.944 0.056
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.945 0.054
I27.1 Kyphoscoliotic heart disease
0.002 0.951 0.047
I27.8 Other specified pulmonary heart diseases
0.002 0.951 0.047
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.002 0.952 0.047
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.952 0.048
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.953 0.046
I27.2 Other secondary pulmonary hypertension
0.002 0.955 0.043
I27.9 Pulmonary heart disease, unspecified
0.002 0.957 0.041
E14.9 Without complications
0.000 0.957 0.043
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.958 0.042
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.959 0.041
N40-N51 Diseases of male genital organs
0.000 0.962 0.038
E14 Unspecified diabetes mellitus
0.000 0.962 0.038
N41 Inflammatory diseases of prostate
0.000 0.963 0.037
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.964 0.036
E10-E14 Diabetes mellitus
0.000 0.964 0.036
N41.1 Chronic prostatitis
0.000 0.966 0.034
N41.0 Acute prostatitis
0.000 0.966 0.034
I95 Hypotension
0.000 0.967 0.033
L72.0 Epidermal cyst
0.000 0.968 0.032
N42 Other disorders of prostate
0.000 0.969 0.031
E10 Insulin-dependent diabetes mellitus
0.000 0.969 0.031
E14.4 With neurological complications
0.000 0.969 0.030
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.971 0.029
N43 Hydrocele and spermatocele
0.000 0.971 0.029
N46 Male infertility
0.000 0.972 0.028
E14.2 Withrenal complications
0.000 0.972 0.028

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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