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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17863057
log Bayes Factor = 17.0844
Chromosome 7   position 89,897,703  (GRCh37) Explore rs17863057 on Ensembl!
Variant rs17863057 is part of Cluster X0277

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
I63 Cerebral infarction
0.991 0.009 0.000
J90-J94 Other diseases of pleura
0.988 0.012 0.000
I50 Heart failure
0.987 0.013 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.987 0.013 0.000
J92 Pleural plaque
0.984 0.016 0.000
F30-F39 Mood [affective] disorders
0.982 0.018 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.981 0.019 0.000
I63.9 Cerebral infarction, unspecified
0.979 0.021 0.000
F31 Bipolar affective disorder
0.974 0.026 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.966 0.034 0.000
J40-J47 Chronic lower respiratory diseases
0.960 0.040 0.000
J92.0 Pleural plaque with presence of asbestos
0.960 0.040 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.958 0.042 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.957 0.043 0.000
M80-M85 Disorders of bone density and structure
0.956 0.044 0.000
Chapter VI Diseases of the nervous system
0.953 0.047 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.951 0.049 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.949 0.051 0.000
J92.9 Pleural plaque without asbestos
0.948 0.052 0.000
D69 Purpura and other haemorrhagic conditions
0.948 0.052 0.000
I67 Other cerebrovascular diseases
0.944 0.056 0.000
I35 Nonrheumatic aortic valve disorders
0.942 0.058 0.000
I34 Nonrheumatic mitral valve disorders
0.942 0.058 0.000
I60 Subarachnoid haemorrhage
0.940 0.060 0.000
I25.1 Atherosclerotic heart disease
0.937 0.063 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.937 0.063 0.000
J45 Asthma
0.933 0.067 0.000
I50.0 Congestive heart failure
0.933 0.067 0.000
M50-M54 Other dorsopathies
0.933 0.067 0.000
G20-G26 Extrapyramidal and movement disorders
0.928 0.072 0.000
I44 Atrioventricular and left bundle-branch block
0.924 0.076 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.921 0.079 0.000
I45 Other conduction disorders
0.918 0.082 0.000
I50.9 Heart failure, unspecified
0.917 0.083 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.914 0.086 0.000
Y57 Other and unspecified drugs and medicaments
0.914 0.086 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.908 0.092 0.000
F20 Schizophrenia
0.907 0.093 0.000
D69.6 Thrombocytopenia, unspecified
0.904 0.096 0.000
I35.0 Aortic (valve) stenosis
0.902 0.098 0.000
Chapter II Neoplasms
0.900 0.100 0.000
E20-E35 Disorders of other endocrine glands
0.900 0.100 0.000
G20 Parkinson's disease
0.896 0.104 0.000
M81 Osteoporosis without pathological fracture
0.890 0.110 0.000
J42 Unspecified chronic bronchitis
0.888 0.112 0.000
M45-M49 Spondylopathies
0.888 0.112 0.000
I25.2 Old myocardial infarction
0.886 0.114 0.000
E70-E90 Metabolic disorders
0.886 0.114 0.000
J45.9 Asthma, unspecified
0.884 0.116 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.881 0.119 0.000
I25.3 Aneurysm of heart
0.881 0.119 0.000
I05-I09 Chronic rheumatic heart diseases
0.881 0.119 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.874 0.126 0.000
M15-M19 Arthrosis
0.873 0.127 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.873 0.127 0.000
J20-J22 Other acute lower respiratory infections
0.873 0.127 0.000
M54 Dorsalgia
0.868 0.132 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.867 0.133 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.865 0.135 0.000
I67.9 Cerebrovascular disease, unspecified
0.865 0.135 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.864 0.136 0.000
E78.5 Hyperlipidaemia, unspecified
0.863 0.137 0.000
Y57.9 Drug or medicament, unspecified
0.861 0.139 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.859 0.141 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.858 0.142 0.000
Y52 Agents primarily affecting the cardiovascular system
0.857 0.143 0.000
I69 Sequelae of cerebrovascular disease
0.856 0.144 0.000
C34 Malignant neoplasm of bronchus and lung
0.853 0.147 0.000
Chapter XXI Factors influencing health status and contact with health services
0.853 0.147 0.000
I34.0 Mitral (valve) insufficiency
0.849 0.151 0.000
Chapter VII Diseases of the eye and adnexa
0.849 0.151 0.000
Q60-Q64 Congenital malformations of the urinary system
0.849 0.151 0.000
F20.9 Schizophrenia, unspecified
0.848 0.152 0.000
I10-I15 Hypertensive diseases
0.848 0.152 0.000
F40 Phobic anxiety disorders
0.847 0.153 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.841 0.159 0.000
I20 Angina pectoris
0.838 0.162 0.000
F99-F99 Unspecified mental disorder
0.838 0.162 0.000
I44.7 Left bundle-branch block, unspecified
0.837 0.163 0.000
M54.5 Low back pain
0.836 0.164 0.000
I45.9 Conduction disorder, unspecified
0.836 0.164 0.000
F45 Somatoform disorders
0.834 0.166 0.000
Chapter XXII Codes for special purposes
0.834 0.166 0.000
J45.0 Predominantly allergic asthma
0.829 0.171 0.000
M20-M25 Other joint disorders
0.826 0.174 0.000
I24 Other acute ischaemic heart diseases
0.826 0.174 0.000
E78.0 Pure hypercholesterolaemia
0.826 0.174 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.826 0.174 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.824 0.176 0.000
I34.1 Mitral (valve) prolapse
0.823 0.177 0.000
D69.5 Secondary thrombocytopenia
0.822 0.178 0.000
M18 Arthrosis of first carpometacarpal joint
0.822 0.178 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.821 0.179 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.819 0.181 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.819 0.181 0.000
W00-W19 Falls
0.819 0.181 0.000
D68 Other coagulation defects
0.818 0.182 0.000
M19 Other arthrosis
0.816 0.184 0.000
C34.9 Bronchus or lung, unspecified
0.815 0.185 0.000
I50.1 Left ventricular failure
0.813 0.187 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.812 0.188 0.000
E27 Other disorders of adrenal gland
0.811 0.189 0.000
M91-M94 Chondropathies
0.811 0.189 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.808 0.192 0.000
V20-V29 Motorcycle rider injured in transport accident
0.808 0.192 0.000
C51-C58 Malignant neoplasms of female genital organs
0.802 0.198 0.000
I08 Multiple valve diseases
0.801 0.199 0.000
I25.5 Ischaemic cardiomyopathy
0.799 0.201 0.000
M81.9 Osteoporosis, unspecified
0.798 0.202 0.000
Y45.0 Opioids and related analgesics
0.798 0.202 0.000
J09-J18 Influenza and pneumonia
0.796 0.204 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.796 0.204 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.793 0.207 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.793 0.207 0.000
J00-J06 Acute upper respiratory infections
0.790 0.210 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.790 0.210 0.000
J94 Other pleural conditions
0.790 0.210 0.000
M80 Osteoporosis with pathological fracture
0.784 0.216 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.783 0.217 0.000
J22 Unspecified acute lower respiratory infection
0.782 0.218 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.781 0.219 0.000
M45 Ankylosing spondylitis
0.780 0.220 0.000
F43 Reaction to severe stress, and adjustment disorders
0.777 0.223 0.000
M54.57 Low back pain (Lumbosacral region)
0.777 0.223 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.777 0.223 0.000
Y45.1 Salicylates
0.776 0.224 0.000
I12 Hypertensive renal disease
0.775 0.225 0.000
J60-J70 Lung diseases due to external agents
0.775 0.225 0.000
I67.2 Cerebral atherosclerosis
0.775 0.225 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.774 0.226 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.774 0.226 0.000
G90-G99 Other disorders of the nervous system
0.774 0.226 0.000
F40.2 Specific (isolated) phobias
0.773 0.227 0.000
I65.2 Occlusion and stenosis of carotid artery
0.771 0.229 0.000
I95 Hypotension
0.771 0.229 0.000
M50 Cervical disk disorders
0.770 0.230 0.000
M46 Other inflammatory spondylopathies
0.769 0.231 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.768 0.232 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.767 0.233 0.000
F31.9 Bipolar affective disorder, unspecified
0.767 0.233 0.000
I35.9 Aortic valve disorder, unspecified
0.766 0.234 0.000
Y43 Primarily systemic agents
0.765 0.235 0.000
D55-D59 Haemolytic anaemias
0.764 0.235 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.763 0.237 0.000
G24 Dystonia
0.762 0.238 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.761 0.239 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.760 0.240 0.000
M81.4 Drug-induced osteoporosis
0.758 0.242 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.755 0.245 0.000
M85 Other disorders of bone density and structure
0.754 0.246 0.000
F25 Schizoaffective disorders
0.754 0.246 0.000
Q61 Cystic kidney disease
0.753 0.246 0.000
F33 Recurrent depressive disorder
0.753 0.247 0.000
F80-F89 Disorders of psychological development
0.753 0.247 0.000
F20.0 Paranoid schizophrenia
0.752 0.248 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.752 0.248 0.000
D69.0 Allergic purpura
0.749 0.251 0.000
W50-W64 Exposure to animate mechanical forces
0.746 0.253 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.745 0.255 0.000
Q50-Q56 Congenital malformations of genital organs
0.743 0.257 0.000
I63.8 Other cerebral infarction
0.743 0.257 0.000
H40-H42 Glaucoma
0.742 0.258 0.000
I45.6 Preexcitation syndrome
0.742 0.258 0.000
J95-J99 Other diseases of the respiratory system
0.741 0.259 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.739 0.261 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.736 0.264 0.000
I44.2 Atrioventricular block, complete
0.735 0.265 0.000
M86-M90 Other osteopathies
0.733 0.267 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.733 0.267 0.000
C56 Malignant neoplasm of ovary
0.732 0.268 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.731 0.269 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.731 0.269 0.000
H06.2 Dysthyroid exophthalmos
0.731 0.269 0.000
D80-D89 Certain disorders involving the immune mechanism
0.730 0.270 0.000
D46 Myelodysplastic syndromes
0.730 0.270 0.000
I62 Other nontraumatic intracranial haemorrhage
0.729 0.270 0.000
M00-M03 Infectious arthropathies
0.729 0.271 0.000
M40-M43 Deforming dorsopathies
0.729 0.271 0.000
I37 Pulmonary valve disorders
0.728 0.271 0.000
C34.3 Lower lobe, bronchus or lung
0.727 0.273 0.000
V40-V49 Car occupant injured in transport accident
0.726 0.274 0.000
F22 Persistent delusional disorders
0.725 0.275 0.000
F99 Mental disorder, not otherwise specified
0.723 0.277 0.000
M19.9 Arthrosis, unspecified
0.723 0.277 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.722 0.278 0.000
J81 Pulmonary oedema
0.722 0.278 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.722 0.278 0.000
V10-V19 Pedal cyclist injured in transport accident
0.722 0.278 0.000
H04 Disorders of lachrymal system
0.721 0.278 0.000
Q00-Q07 Congenital malformations of the nervous system
0.721 0.279 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.721 0.279 0.000
I61 Intracerebral haemorrhage
0.721 0.279 0.000
I22 Subsequent myocardial infarction
0.720 0.280 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.720 0.280 0.000
I67.8 Other specified cerebrovascular diseases
0.719 0.281 0.000
Y52.1 Calcium-channel blockers
0.719 0.281 0.000
M54.59 Low back pain (Site unspecified)
0.719 0.281 0.000
I44.3 Other and unspecified atrioventricular block
0.718 0.282 0.000
M54.3 Sciatica
0.718 0.282 0.000
I45.3 Trifascicular block
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.717 0.283 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.717 0.283 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
I25.6 Silent myocardial ischaemia
0.715 0.285 0.000
I25.4 Coronary artery aneurysm
0.715 0.285 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.715 0.285 0.000
M60-M63 Disorders of muscles
0.715 0.285 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.714 0.286 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.713 0.286 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.286 0.000
Y10-Y34 Event of undetermined intent
0.713 0.286 0.000
Y00-Y09 Assault
0.713 0.286 0.000
X85-X99 Assault
0.713 0.286 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.713 0.286 0.000
X50-X57 Overexertion, travel and privation
0.713 0.286 0.000
X30-X39 Exposure to forces of nature
0.713 0.286 0.000
X10-X19 Contact with heat and hot substances
0.713 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.713 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.713 0.286 0.000
W75-W84 Other accidental threats to breathing
0.713 0.286 0.000
W65-W74 Accidental drowning and submersion
0.713 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.713 0.286 0.000
V95-V97 Air and space transport accidents
0.713 0.286 0.000
V90-V94 Water transport accidents
0.713 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.713 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.713 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.713 0.286 0.000
I27 Other pulmonary heart diseases
0.713 0.287 0.000
D47.2 Monoclonal gammopathy
0.713 0.287 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.713 0.287 0.000
E26 Hyperaldosteronism
0.713 0.287 0.000
X20-X29 Contact with venomous animals and plants
0.713 0.287 0.000
J40 Bronchitis, not specified as acute or chronic
0.712 0.287 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.712 0.288 0.000
C78.2 Secondary malignant neoplasm of pleura
0.712 0.288 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.711 0.289 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.711 0.289 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.711 0.289 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.711 0.289 0.000
I12.0 Hypertensive renal disease with renal failure
0.710 0.290 0.000
M24 Other specific joint derangements
0.710 0.290 0.000
M65-M68 Disorders of synovium and tendon
0.709 0.291 0.000
Y89 Sequelae of other external causes
0.708 0.292 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.708 0.292 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.708 0.292 0.000
M53 Other dorsopathies, not elsewhere classified
0.708 0.292 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.708 0.292 0.000
M84 Disorders of continuity of bone
0.708 0.292 0.000
Y59 Other and unspecified vaccines and biological substances
0.708 0.292 0.000
Y58 Bacterial vaccines
0.708 0.292 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.708 0.292 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.708 0.292 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.708 0.292 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.708 0.292 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.708 0.292 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.708 0.292 0.000
Y48 Anaesthetics and therapeutic gases
0.708 0.292 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.708 0.292 0.000
Y44 Agents primarily affecting blood constituents
0.708 0.292 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.708 0.292 0.000
Q80-Q89 Other congenital malformations
0.707 0.293 0.000
J43 Emphysema
0.706 0.294 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.706 0.294 0.000
V80-V89 Other land transport accidents
0.706 0.294 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.706 0.294 0.000
I20.9 Angina pectoris, unspecified
0.706 0.294 0.000
E34 Other endocrine disorders
0.705 0.295 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.705 0.295 0.000
G30-G32 Other degenerative diseases of the nervous system
0.705 0.295 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.704 0.296 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.704 0.296 0.000
F38 Other mood [affective] disorders
0.704 0.296 0.000
F34 Persistent mood [affective] disorders
0.704 0.296 0.000
F30 Manic episode
0.704 0.296 0.000
F39 Unspecified mood [affective] disorder
0.704 0.296 0.000
G70-G73 Diseases of myoneural junction and muscle
0.703 0.297 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.703 0.297 0.000
G25 Other extrapyramidal and movement disorders
0.703 0.297 0.000
F23 Acute and transient psychotic disorders
0.700 0.300 0.000
I36 Nonrheumatic tricuspid valve disorders
0.700 0.300 0.000
J84 Other interstitial pulmonary diseases
0.699 0.301 0.000
E27.2 Addisonian crisis
0.699 0.301 0.000
I95.9 Hypotension, unspecified
0.699 0.301 0.000
F31.8 Other bipolar affective disorders
0.698 0.302 0.000
F31.7 Bipolar affective disorder, currently in remission
0.698 0.302 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.698 0.302 0.000
J02 Acute pharyngitis
0.698 0.302 0.000
Y45.2 Propionic acid derivatives
0.698 0.302 0.000
F45.8 Other somatoform disorders
0.696 0.304 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.695 0.305 0.000
M21 Other acquired deformities of limbs
0.695 0.305 0.000
I67.1 Cerebral aneurysm, nonruptured
0.694 0.306 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.694 0.306 0.000
I51 Complications and ill-defined descriptions of heart disease
0.694 0.306 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.694 0.306 0.000
J93 Pneumothorax
0.693 0.307 0.000
Y88 Sequelae of surgical and medical care as external cause
0.692 0.308 0.000
W10 Fall on and from stairs and steps
0.692 0.308 0.000
F45.3 Somatoform autonomic dysfunction
0.691 0.309 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.689 0.311 0.000
J41 Simple and mucopurulent chronic bronchitis
0.688 0.311 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.688 0.312 0.000
D67 Hereditary factor IX deficiency
0.687 0.313 0.000
D66 Hereditary factor VIII deficiency
0.687 0.313 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.687 0.313 0.000
H53-H54 Visual disturbances and blindness
0.687 0.313 0.000
D68.8 Other specified coagulation defects
0.686 0.314 0.000
M19.0 Primary arthrosis of other joints
0.686 0.314 0.000
F28 Other nonorganic psychotic disorders
0.686 0.314 0.000
F24 Induced delusional disorder
0.686 0.314 0.000
F21 Schizotypal disorder
0.686 0.314 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.686 0.314 0.000
E27.1 Primary adrenocortical insufficiency
0.686 0.314 0.000
M83 Adult osteomalacia
0.686 0.314 0.000
M82 Osteoporosis in diseases classified elsewhere
0.686 0.314 0.000
X60-X84 Intentional self-harm
0.685 0.314 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.685 0.315 0.000
I35.1 Aortic (valve) insufficiency
0.684 0.316 0.000
I99 Other and unspecified disorders of circulatory system
0.684 0.316 0.000
I44.6 Other and unspecified fascicular block
0.684 0.316 0.000
F29 Unspecified nonorganic psychosis
0.684 0.316 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.683 0.317 0.000
F48 Other neurotic disorders
0.682 0.318 0.000
F44 Dissociative [conversion] disorders
0.682 0.318 0.000
E78.4 Other hyperlipidaemia
0.681 0.319 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.681 0.319 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.680 0.320 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.680 0.320 0.000
Q35-Q37 Cleft lip and cleft palate
0.680 0.320 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.680 0.320 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.680 0.320 0.000
D69.9 Haemorrhagic condition, unspecified
0.679 0.321 0.000
D69.8 Other specified haemorrhagic conditions
0.679 0.321 0.000
D69.4 Other primary thrombocytopenia
0.679 0.321 0.000
D69.2 Other nonthrombocytopenic purpura
0.679 0.321 0.000
D69.1 Qualitative platelet defects
0.679 0.321 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.679 0.321 0.000
Y86 Sequelae of other accidents
0.679 0.321 0.000
M31 Other necrotising vasculopathies
0.678 0.322 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.677 0.323 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.677 0.323 0.000
I67.5 Moyamoya disease
0.677 0.323 0.000
I67.4 Hypertensive encephalopathy
0.677 0.323 0.000
I67.3 Progressive vascular leukoencephalopathy
0.677 0.323 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.677 0.323 0.000
M25 Other joint disorders, not elsewhere classified
0.676 0.324 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.676 0.324 0.000
I45.2 Bifascicular block
0.675 0.324 0.000
M54.50 Low back pain (Multiple sites in spine)
0.675 0.324 0.000
E23 Hypofunction and other disorders of pituitary gland
0.675 0.325 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.675 0.325 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.675 0.325 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.675 0.325 0.000
I60.8 Other subarachnoid haemorrhage
0.674 0.326 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.674 0.326 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.674 0.326 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.674 0.326 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.674 0.326 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.674 0.326 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.674 0.326 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.674 0.326 0.000
F60-F69 Disorders of adult personality and behaviour
0.674 0.326 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.674 0.326 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.674 0.326 0.000
F42 Obsessive-compulsive disorder
0.673 0.327 0.000
I30 Acute pericarditis
0.672 0.328 0.000
M54.55 Low back pain (Thoracolumbar region)
0.671 0.329 0.000
J91 Pleural effusion in conditions classified elsewhere
0.670 0.330 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.670 0.330 0.000
Y42.7 Androgens and anabolic congeners
0.669 0.331 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.669 0.331 0.000
J45.8 Mixed asthma
0.669 0.331 0.000
J45.1 Nonallergic asthma
0.669 0.331 0.000
Z03.4 Observation for suspected myocardial infarction
0.669 0.331 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.668 0.332 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.667 0.333 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.667 0.333 0.000
I45.5 Other specified heart block
0.666 0.333 0.000
D47.1 Chronic myeloproliferative disease
0.666 0.334 0.000
G23 Other degenerative diseases of basal ganglia
0.665 0.334 0.000
G21 Secondary Parkinsonism
0.665 0.334 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.665 0.334 0.000
G22 Parkinsonism in diseases classified elsewhere
0.665 0.334 0.000
H40 Glaucoma
0.666 0.334 0.000
I24.8 Other forms of acute ischaemic heart disease
0.665 0.335 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.663 0.337 0.000
I44.5 Left posterior fascicular block
0.663 0.337 0.000
I44.4 Left anterior fascicular block
0.663 0.337 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.662 0.338 0.000
I44.1 Atrioventricular block, second degree
0.661 0.339 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.661 0.339 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.661 0.339 0.000
Y45.8 Other analgesics and antipyretics
0.661 0.339 0.000
Y45.5 4-Aminophenol derivatives
0.661 0.339 0.000
Y45.4 Antirheumatics
0.661 0.339 0.000
I33 Acute and subacute endocarditis
0.661 0.339 0.000
Z73 Problems related to life-management difficulty
0.660 0.340 0.000
I46 Cardiac arrest
0.659 0.340 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.659 0.341 0.000
E22 Hyperfunction of pituitary gland
0.659 0.341 0.000
M22 Disorders of patella
0.659 0.341 0.000
I45.8 Other specified conduction disorders
0.658 0.342 0.000
I45.4 Nonspecific intraventricular block
0.658 0.342 0.000
I45.0 Right fascicular block
0.658 0.342 0.000
I97.1 Other functional disturbances following cardiac surgery
0.655 0.345 0.000
Y57.8 Other drugs and medicaments
0.655 0.345 0.000
Y57.7 Vitamins, not elsewhere classified
0.655 0.345 0.000
Y57.6 Other diagnostic agents
0.655 0.345 0.000
Y57.5 X-ray contrast media
0.655 0.345 0.000
Y57.4 Pharmaceutical excipients
0.655 0.345 0.000
Y57.3 Alcohol deterrents
0.655 0.345 0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified
0.655 0.345 0.000
Y57.1 Lipotropic drugs
0.655 0.345 0.000
Y57.0 Appetite depressants [anorectics]
0.655 0.345 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.653 0.347 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.653 0.347 0.000
C34.1 Upper lobe, bronchus or lung
0.652 0.348 0.000
I69.3 Sequelae of cerebral infarction
0.652 0.348 0.000
E40-E46 Malnutrition
0.652 0.348 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.651 0.349 0.000
F20.8 Other schizophrenia
0.650 0.350 0.000
F20.6 Simple schizophrenia
0.650 0.350 0.000
F20.5 Residual schizophrenia
0.650 0.350 0.000
F20.4 Postschizophrenic depression
0.650 0.350 0.000
F20.3 Undifferentiated schizophrenia
0.650 0.350 0.000
F20.2 Catatonic schizophrenia
0.650 0.350 0.000
F20.1 Hebephrenic schizophrenia
0.650 0.350 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.650 0.350 0.000
D45 Polycythaemia vera
0.649 0.351 0.000
D60-D64 Aplastic and other anaemias
0.649 0.351 0.000
G91 Hydrocephalus
0.648 0.352 0.000
E28 Ovarian dysfunction
0.648 0.352 0.000
D68.2 Hereditary deficiency of other clotting factors
0.647 0.352 0.000
F41 Other anxiety disorders
0.646 0.353 0.000
C34.2 Middle lobe, bronchus or lung
0.646 0.354 0.000
I20.8 Other forms of angina pectoris
0.646 0.354 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.645 0.355 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.645 0.355 0.000
E32 Diseases of thymus
0.645 0.355 0.000
E31 Polyglandular dysfunction
0.645 0.355 0.000
E30 Disorders of puberty, not elsewhere classified
0.645 0.355 0.000
E25 Adrenogenital disorders
0.645 0.355 0.000
E24 Cushing's syndrome
0.645 0.355 0.000
E20 Hypoparathyroidism
0.645 0.355 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.645 0.355 0.000
H01 Other inflammation of eyelid
0.645 0.355 0.000
J94.2 Haemothorax
0.645 0.355 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.645 0.355 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.643 0.357 0.000
G24.9 Dystonia, unspecified
0.643 0.357 0.000
E88 Other metabolic disorders
0.642 0.358 0.000
M93 Other osteochondropathies
0.641 0.359 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.640 0.360 0.000
M50.1 Cervical disk disorder with radiculopathy
0.640 0.360 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.638 0.362 0.000
M81.8 Other osteoporosis
0.638 0.362 0.000
M81.6 Localised osteoporosis [Lequesne]
0.638 0.362 0.000
M81.5 Idiopathic osteoporosis
0.638 0.362 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.638 0.362 0.000
M81.2 Osteoporosis of disuse
0.638 0.362 0.000
M81.1 Postoophorectomy osteoporosis
0.638 0.362 0.000
M81.0 Postmenopausal osteoporosis
0.638 0.362 0.000
I42 Cardiomyopathy
0.637 0.363 0.000
C32 Malignant neoplasm of larynx
0.637 0.363 0.000
M49 Spondylopathies in diseases classified elsewhere
0.637 0.363 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.636 0.364 0.000
G95 Other diseases of spinal cord
0.636 0.364 0.000
E85 Amyloidosis
0.636 0.364 0.000
E84 Cystic fibrosis
0.636 0.364 0.000
E79 Disorders of purine and pyrimidine metabolism
0.636 0.364 0.000
E77 Disorders of glycoprotein metabolism
0.636 0.364 0.000
E76 Disorders of glycosaminoglycan metabolism
0.636 0.364 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.636 0.364 0.000
E74 Other disorders of carbohydrate metabolism
0.636 0.364 0.000
E73 Lactose intolerance
0.636 0.364 0.000
E72 Other disorders of amino-acid metabolism
0.636 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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