TreeWAS – Variant ID: rs1793257

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.017	0.983	0.000
I69 Sequelae of cerebrovascular disease	0.017	0.983	0.000
I69.3 Sequelae of cerebral infarction	0.016	0.984	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.014	0.986	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.013	0.987	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.012	0.988	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.012	0.988	0.000
I60 Subarachnoid haemorrhage	0.012	0.988	0.000
I60-I69 Cerebrovascular diseases	0.012	0.988	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.011	0.989	0.000
I60.8 Other subarachnoid haemorrhage	0.010	0.990	0.000
I62 Other nontraumatic intracranial haemorrhage	0.010	0.990	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.010	0.990	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.009	0.991	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.991	0.009
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.009	0.991	0.000
I67 Other cerebrovascular diseases	0.009	0.991	0.000
I67.1 Cerebral aneurysm, nonruptured	0.009	0.991	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.009	0.991	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.009	0.991	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.009	0.991	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.009	0.991	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.009	0.991	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.009	0.991	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.008	0.991	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.008	0.991	0.000
I61 Intracerebral haemorrhage	0.008	0.992	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.992	0.008
Z95.0 Presence of cardiac pacemaker	0.000	0.992	0.008
Z95.2 Presence of prosthetic heart valve	0.000	0.992	0.008
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.992	0.008
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.007	0.992	0.000
I62.1 Nontraumatic extradural haemorrhage	0.007	0.992	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.992	0.007
C79 Secondary malignant neoplasm of other sites	0.000	0.993	0.007
I63 Cerebral infarction	0.007	0.993	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.007	0.993	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.007	0.993	0.000
J33.9 Nasal polyp, unspecified	0.000	0.993	0.007
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.007	0.993	0.000
Z95.4 Presence of other heart-valve replacement	0.000	0.993	0.007
I67.7 Cerebral arteritis, not elsewhere classified	0.007	0.993	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.007	0.993	0.000
I67.5 Moyamoya disease	0.007	0.993	0.000
I67.4 Hypertensive encephalopathy	0.007	0.993	0.000
I67.3 Progressive vascular leukoencephalopathy	0.007	0.993	0.000
I61.8 Other intracerebral haemorrhage	0.007	0.993	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.994	0.006
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.006	0.994	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.006	0.994	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.006	0.994	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.006	0.994	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.006	0.994	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.006	0.994	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.006	0.994	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.006	0.994	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.006	0.994	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
I68.0 Cerebral amyloid angiopathy	0.006	0.994	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.006	0.994	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.006	0.994	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.006	0.994	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.006	0.994	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.006	0.994	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.006	0.994	0.000
C79.2 Secondary malignant neoplasm of skin	0.000	0.994	0.006
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.006	0.994	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.006	0.994	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
I67.2 Cerebral atherosclerosis	0.006	0.994	0.000
I67.8 Other specified cerebrovascular diseases	0.006	0.994	0.000
Z95.1 Presence of aortocoronary bypass graft	0.000	0.994	0.006
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.994	0.006
C79.6 Secondary malignant neoplasm of ovary	0.000	0.994	0.006
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.994	0.005
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.994	0.005
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.994	0.005
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.005	0.994	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.005	0.994	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.005	0.994	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.005	0.994	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.005	0.995	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.005	0.995	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.005	0.995	0.000
I65.1 Occlusion and stenosis of basilar artery	0.005	0.995	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.005	0.995	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.995	0.005
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.005	0.995	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
C67.9 Bladder, unspecified	0.005	0.995	0.000
I63.9 Cerebral infarction, unspecified	0.005	0.995	0.000
I63.8 Other cerebral infarction	0.005	0.995	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.004	0.995	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.004	0.995	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.004	0.995	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.004	0.995	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.004	0.995	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.004	0.995	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.004	0.995	0.000
Z95.3 Presence of xenogenic heart valve	0.000	0.995	0.004
S80.9 Superficial injury of lower leg, unspecified	0.004	0.996	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.996	0.004
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.004	0.996	0.000
O82.0 Delivery by elective Caesarean section	0.004	0.996	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.996	0.004
M20.5 Other deformities of toe(s) (acquired)	0.004	0.996	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.004	0.996	0.000
C67 Malignant neoplasm of bladder	0.004	0.996	0.000
I65.2 Occlusion and stenosis of carotid artery	0.004	0.996	0.000
I67.9 Cerebrovascular disease, unspecified	0.004	0.996	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.004	0.996	0.000
C67.6 Ureteric orifice	0.004	0.996	0.000
O82 Single delivery by Caesarean section	0.004	0.996	0.000
S80 Superficial injury of lower leg	0.004	0.996	0.000
C77.2 Intra-abdominal lymph nodes	0.000	0.996	0.004
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.996	0.004
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.004	0.996	0.000
S80-S89 Injuries to the knee and lower leg	0.004	0.996	0.000
S83.2 Tear of meniscus, current	0.003	0.996	0.000
C67.0 Trigone of bladder	0.003	0.996	0.000
O80-O84 Delivery	0.004	0.996	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
O97 Death from sequelae of direct obstetric causes	0.003	0.996	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.003	0.996	0.000
O95 Obstetric death of unspecified cause	0.003	0.996	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.003	0.996	0.000
C67.8 Overlapping lesion of bladder	0.003	0.997	0.000
C80 Malignant neoplasm without specification of site	0.000	0.997	0.003
I50.9 Heart failure, unspecified	0.000	0.997	0.003
Chapter XV Pregnancy, childbirth and the puerperium	0.003	0.997	0.000
B34.9 Viral infection, unspecified	0.003	0.997	0.000
S89 Other and unspecified injuries of lower leg	0.003	0.997	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.000	0.997	0.003
M25.76 Osteophyte (Lower leg)	0.003	0.997	0.000
C67.3 Anterior wall of bladder	0.003	0.997	0.000
C77.8 Lymph nodes of multiple regions	0.000	0.997	0.003
S83.7 Injury to multiple structures of knee	0.003	0.997	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.003	0.997	0.000
S83.3 Tear of articular cartilage of knee, current	0.003	0.997	0.000
S83.1 Dislocation of knee	0.003	0.997	0.000
S83.0 Dislocation of patella	0.003	0.997	0.000
C67.7 Urachus	0.003	0.997	0.000
C67.5 Bladder neck	0.003	0.997	0.000
J33 Nasal polyp	0.000	0.997	0.003
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.003	0.997	0.000
C67.1 Dome of bladder	0.003	0.997	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.003	0.997	0.000
O16 Unspecified maternal hypertension	0.003	0.997	0.000
O60-O75 Complications of labour and delivery	0.003	0.997	0.000
S89.9 Unspecified injury of lower leg	0.003	0.997	0.000
S81 Open wound of lower leg	0.003	0.997	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.997	0.003
C67.2 Lateral wall of bladder	0.003	0.997	0.000
T93 Sequelae of injuries of lower limb	0.003	0.997	0.000
C80.9 Malignant neoplasm, unspecified	0.000	0.997	0.003
O82.9 Delivery by Caesarean section, unspecified	0.003	0.997	0.000
O82.8 Other single delivery by Caesarean section	0.003	0.997	0.000
O82.2 Delivery by Caesarean hysterectomy	0.003	0.997	0.000
S80.7 Multiple superficial injuries of lower leg	0.003	0.997	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.003	0.997	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.000	0.997	0.003
C77.9 Lymph node, unspecified	0.000	0.997	0.003
O66 Other obstructed labour	0.003	0.997	0.000
C67.4 Posterior wall of bladder	0.003	0.997	0.000
O82.1 Delivery by emergency Caesarean section	0.003	0.997	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.003	0.997	0.000
S88 Traumatic amputation of lower leg	0.003	0.997	0.000
S87 Crushing injury of lower leg	0.003	0.997	0.000
S86 Injury of muscle and tendon at lower leg level	0.003	0.997	0.000
S85 Injury of blood vessels at lower leg level	0.003	0.997	0.000
S84 Injury of nerves at lower leg level	0.003	0.997	0.000
O80 Single spontaneous delivery	0.003	0.997	0.000
O21 Excessive vomiting in pregnancy	0.003	0.997	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.003	0.997	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.003	0.997	0.000
C77.4 Inguinal and lower limb lymph nodes	0.000	0.997	0.003
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.003	0.997	0.000
O84 Multiple delivery	0.003	0.997	0.000
O83 Other assisted single delivery	0.003	0.997	0.000
O81 Single delivery by forceps and vacuum extractor	0.003	0.997	0.000
S90-S99 Injuries to the ankle and foot	0.003	0.997	0.000
O96.9 Death from unspecified obstetric cause	0.003	0.997	0.000
O96.1 Death from indirect obstetric cause	0.003	0.997	0.000
O96.0 Death from direct obstetric cause	0.003	0.997	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.003	0.997	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.003	0.997	0.000
O97.0 Death from sequelae of direct obstetric cause	0.003	0.997	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
J33.8 Other polyp of sinus	0.000	0.997	0.003
O66.0 Obstructed labour due to shoulder dystocia	0.003	0.997	0.000
O80.9 Single spontaneous delivery, unspecified	0.003	0.997	0.000
S81.8 Open wound of other parts of lower leg	0.003	0.997	0.000
M25.7 Osteophyte	0.003	0.997	0.000
O71 Other obstetric trauma	0.003	0.997	0.000
M25.71 Osteophyte (Shoulder region)	0.003	0.997	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.003	0.997	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.003	0.997	0.000
O72 Postpartum haemorrhage	0.003	0.997	0.000
C77.3 Axillary and upper limb lymph nodes	0.000	0.997	0.003
S81.0 Open wound of knee	0.003	0.997	0.000
O69.8 Labour and delivery complicated by other cord complications	0.003	0.997	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.003	0.997	0.000
O73 Retained placenta and membranes, without haemorrhage	0.003	0.997	0.000
S91 Open wound of ankle and foot	0.003	0.997	0.000
T93.0 Sequelae of open wound of lower limb	0.003	0.997	0.000
S92 Fracture of foot, except ankle	0.003	0.997	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.997	0.003
S80.0 Contusion of knee	0.002	0.997	0.000
S89.8 Other specified injuries of lower leg	0.002	0.997	0.000
S89.7 Multiple injuries of lower leg	0.002	0.997	0.000
S89.1 Other specified injuries of lower leg	0.002	0.997	0.000
S89.0 Multiple injuries of lower leg	0.002	0.997	0.000
S91.3 Open wound of other parts of foot	0.003	0.997	0.000
O62 Abnormalities of forces of labour	0.003	0.997	0.000
C76.8 Overlapping lesion of other and ill-defined sites	0.000	0.997	0.002
C76.7 Other ill-defined sites	0.000	0.997	0.002
C76.5 Lower limb	0.000	0.997	0.002
C76.4 Upper limb	0.000	0.997	0.002
C76.3 Pelvis	0.000	0.997	0.002
C76.2 Abdomen	0.000	0.997	0.002
C76.1 Thorax	0.000	0.997	0.002
C76.0 Head, face and neck	0.000	0.997	0.002
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.997	0.000
O85-O92 Complications predominantly related to the puerperium	0.002	0.997	0.000
S80.8 Other superficial injuries of lower leg	0.002	0.997	0.000
S90 Superficial injury of ankle and foot	0.003	0.997	0.000
C77.5 Intrapelvic lymph nodes	0.000	0.997	0.002
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.997	0.002
C78.7 Secondary malignant neoplasm of liver	0.000	0.997	0.003
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.997	0.003
J33.1 Polypoid sinus degeneration	0.000	0.997	0.002
O75.2 Pyrexia during labour, not elsewhere classified	0.002	0.997	0.000
O61 Failed induction of labour	0.002	0.997	0.000
O71.7 Obstetric haematoma of pelvis	0.002	0.997	0.000
S01.9 Open wound of head, part unspecified	0.003	0.997	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.002	0.997	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.002	0.997	0.000
O15 Eclampsia	0.002	0.997	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.002	0.997	0.000
S01.3 Open wound of ear	0.002	0.997	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.002	0.997	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.002	0.997	0.000
O74 Complications of anaesthesia during labour and delivery	0.002	0.997	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.002	0.997	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.002	0.997	0.000
O60 Preterm delivery	0.002	0.997	0.000
S81.7 Multiple open wounds of lower leg	0.002	0.998	0.000
S92.5 Fracture of other toe	0.002	0.998	0.000
C77.1 Intrathoracic lymph nodes	0.000	0.998	0.002
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.998	0.002
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.998	0.002
C78.1 Secondary malignant neoplasm of mediastinum	0.000	0.998	0.002
O21.0 Mild hyperemesis gravidarum	0.002	0.998	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.002	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.002	0.998	0.000
O46.9 Antepartum haemorrhage, unspecified	0.002	0.998	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.002	0.998	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.002	0.998	0.000
T93.1 Sequelae of fracture of femur	0.002	0.998	0.000
O64.1 Obstructed labour due to breech presentation	0.002	0.998	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.002	0.998	0.000
M25.77 Osteophyte (Ankle and foot)	0.002	0.998	0.000
C78.2 Secondary malignant neoplasm of pleura	0.000	0.998	0.002
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.002	0.998	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.002	0.998	0.000
O24 Diabetes mellitus in pregnancy	0.002	0.998	0.000
T91 Sequelae of injuries of neck and trunk	0.002	0.998	0.000
T90 Sequelae of injuries of head	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
O44 Placenta praevia	0.002	0.998	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.002	0.998	0.000
O66.9 Obstructed labour, unspecified	0.002	0.998	0.000
O66.8 Other specified obstructed labour	0.002	0.998	0.000
O66.4 Failed trial of labour, unspecified	0.002	0.998	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.002	0.998	0.000
O66.2 Obstructed labour due to unusually large foetus	0.002	0.998	0.000
O66.1 Obstructed labour due to locked twins	0.002	0.998	0.000
O28 Abnormal findings on antenatal screening of mother	0.002	0.998	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.998	0.002
O69.2 Labour and delivery complicated by other cord entanglement	0.002	0.998	0.000
S01 Open wound of head	0.002	0.998	0.000
O29 Complications of anaesthesia during pregnancy	0.002	0.998	0.000
O22 Venous complications in pregnancy	0.002	0.998	0.000
O25 Malnutrition in pregnancy	0.002	0.998	0.000
M25.78 Osteophyte (Other)	0.002	0.998	0.000
O80.8 Other single spontaneous delivery	0.002	0.998	0.000
O80.1 Spontaneous breech delivery	0.002	0.998	0.000
S01.4 Open wound of cheek and temporomandibular area	0.002	0.998	0.000
S69.9 Unspecified injury of wrist and hand	0.002	0.998	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.002	0.998	0.000
S84.8 Injury of other nerves at lower leg level	0.002	0.998	0.000
S84.7 Injury of multiple nerves at lower leg level	0.002	0.998	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.002	0.998	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.002	0.998	0.000
S84.0 Injury of tibial nerve at lower leg level	0.002	0.998	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.002	0.998	0.000
S85.8 Injury of other blood vessels at lower leg level	0.002	0.998	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.002	0.998	0.000
S85.5 Injury of popliteal vein	0.002	0.998	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.002	0.998	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.002	0.998	0.000
S85.2 Injury of peroneal artery	0.002	0.998	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.002	0.998	0.000
S85.0 Injury of popliteal artery	0.002	0.998	0.000
S86.0 Injury of Achilles tendon	0.002	0.998	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.002	0.998	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.002	0.998	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.002	0.998	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.002	0.998	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.002	0.998	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.002	0.998	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.002	0.998	0.000
S87.0 Crushing injury of knee	0.002	0.998	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.002	0.998	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.002	0.998	0.000
S88.0 Traumatic amputation at knee level	0.002	0.998	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.002	0.998	0.000
O21.9 Vomiting of pregnancy, unspecified	0.002	0.998	0.000
O21.8 Other vomiting complicating pregnancy	0.002	0.998	0.000
O21.2 Late vomiting of pregnancy	0.002	0.998	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.002	0.998	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.002	0.998	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.002	0.998	0.000
O69.3 Labour and delivery complicated by short cord	0.002	0.998	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
T98 Sequelae of other and unspecified effects of external causes	0.002	0.998	0.000
T95 Sequelae of burns, corrosions and frostbite	0.002	0.998	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
S20-S29 Injuries to the thorax	0.002	0.998	0.000
M25.74 Osteophyte (Hand)	0.002	0.998	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.002	0.998	0.000
O81.5 Delivery by combination of forceps and vacuum extractor	0.002	0.998	0.000
O81.4 Vacuum extractor delivery	0.002	0.998	0.000
O81.3 Other and unspecified forceps delivery	0.002	0.998	0.000
O81.2 Mid-cavity forceps with rotation	0.002	0.998	0.000
O81.1 Mid-cavity forceps delivery	0.002	0.998	0.000
O81.0 Low forceps delivery	0.002	0.998	0.000
O83.9 Assisted single delivery, unspecified	0.002	0.998	0.000
O83.8 Other specified assisted single delivery	0.002	0.998	0.000
O83.4 Destructive operation for delivery	0.002	0.998	0.000
O83.3 Delivery of viable foetus in abdominal pregnancy	0.002	0.998	0.000
O83.2 Other manipulation-assisted delivery	0.002	0.998	0.000
O83.1 Other assisted breech delivery	0.002	0.998	0.000
O83.0 Breech extraction	0.002	0.998	0.000
O84.9 Multiple delivery, unspecified	0.002	0.998	0.000
O84.8 Other multiple delivery	0.002	0.998	0.000
O84.2 Multiple delivery, all by Caesarean section	0.002	0.998	0.000
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.002	0.998	0.000
O84.0 Multiple delivery, all spontaneous	0.002	0.998	0.000
T90.5 Sequelae of intracranial injury	0.002	0.998	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.002	0.998	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.002	0.998	0.000
S99 Other and unspecified injuries of ankle and foot	0.002	0.998	0.000
S98 Traumatic amputation of ankle and foot	0.002	0.998	0.000
S97 Crushing injury of ankle and foot	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.998	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.998	0.002
S92.70 Multiple fractures of foot (closed)	0.002	0.998	0.000
M25.79 Osteophyte (Site unspecified)	0.002	0.998	0.000
M25.73 Osteophyte (Forearm)	0.002	0.998	0.000
M25.72 Osteophyte (Upper arm)	0.002	0.998	0.000
M25.70 Osteophyte (Multiple sites)	0.002	0.998	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.002	0.998	0.000
O71.9 Obstetric trauma, unspecified	0.002	0.998	0.000
O71.8 Other specified obstetric trauma	0.002	0.998	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.002	0.998	0.000
O71.5 Other obstetric injury to pelvic organs	0.002	0.998	0.000
O71.4 Obstetric high vaginal laceration alone	0.002	0.998	0.000
O71.3 Obstetric laceration of cervix	0.002	0.998	0.000
O71.2 Postpartum inversion of uterus	0.002	0.998	0.000
O71.1 Rupture of uterus during labour	0.002	0.998	0.000
O71.0 Rupture of uterus before onset of labour	0.002	0.998	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.002	0.998	0.000
O20 Haemorrhage in early pregnancy	0.002	0.998	0.000
C77.0 Lymph nodes of head, face and neck	0.000	0.998	0.002
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.998	0.002
S10-S19 Injuries to the neck	0.002	0.998	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.002	0.998	0.000
O62.2 Other uterine inertia	0.002	0.998	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.002	0.998	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.002	0.998	0.000
T92 Sequelae of injuries of upper limb	0.002	0.998	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.002	0.998	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.002	0.998	0.000
O62.3 Precipitate labour	0.002	0.998	0.000
O72.3 Postpartum coagulation defects	0.002	0.998	0.000
S12 Fracture of neck	0.002	0.998	0.000
O72.0 Third-stage haemorrhage	0.002	0.998	0.000
O75.9 Complication of labour and delivery, unspecified	0.002	0.998	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.002	0.998	0.000
O75.4 Other complications of obstetric surgery and procedures	0.002	0.998	0.000
O75.3 Other infection during labour	0.002	0.998	0.000
O75.1 Shock during or following labour and delivery	0.002	0.998	0.000
O75.0 Maternal distress during labour and delivery	0.002	0.998	0.000
S91.7 Multiple open wounds of ankle and foot	0.002	0.998	0.000
S91.2 Open wound of toe(s) with damage to nail	0.002	0.998	0.000
S91.1 Open wound of toe(s) without damage to nail	0.002	0.998	0.000
S91.0 Open wound of ankle	0.002	0.998	0.000
S92.3 Fracture of metatarsal bone	0.002	0.998	0.000
S12.1 Fracture of second cervical vertebra	0.002	0.998	0.000
S92.9 Fracture of foot, unspecified	0.002	0.998	0.000
S92.4 Fracture of great toe	0.002	0.998	0.000
S92.1 Fracture of talus	0.002	0.998	0.000
O23 Infections of genito-urinary tract in pregnancy	0.002	0.998	0.000
O61.0 Failed medical induction of labour	0.002	0.998	0.000
O62.9 Abnormality of forces of labour, unspecified	0.002	0.998	0.000
O62.8 Other abnormalities of forces of labour	0.002	0.998	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.002	0.998	0.000
O62.1 Secondary uterine inertia	0.002	0.998	0.000
O62.0 Primary inadequate contractions	0.002	0.998	0.000
T79-T79 Certain early complications of trauma	0.002	0.998	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.002	0.998	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O72.1 Other immediate postpartum haemorrhage	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
T91.1 Sequelae of fracture of spine	0.002	0.998	0.000
T94.1 Sequelae of injuries, not specified by body region	0.002	0.998	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.002	0.998	0.000
O91 Infections of breast associated with childbirth	0.002	0.998	0.000
O89 Complications of anaesthesia during the puerperium	0.002	0.998	0.000
O88 Obstetric embolism	0.002	0.998	0.000
O87 Venous complications in the puerperium	0.002	0.998	0.000
O85 Puerperal sepsis	0.002	0.998	0.000
S22.30 Fracture of rib (closed)	0.002	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.002	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
S90.0 Contusion of ankle	0.002	0.998	0.000
O86 Other puerperal infections	0.002	0.998	0.000
S27 Injury of other and unspecified intrathoracic organs	0.002	0.998	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.002	0.998	0.000
O12.1 Gestational proteinuria	0.002	0.998	0.000
O44.1 Placenta praevia with haemorrhage	0.002	0.998	0.000
J33.0 Polyp of nasal cavity	0.000	0.998	0.002
O61.9 Failed induction of labour, unspecified	0.002	0.998	0.000
O61.8 Other failed induction of labour	0.002	0.998	0.000
O61.1 Failed instrumental induction of labour	0.002	0.998	0.000
O75.8 Other specified complications of labour and delivery	0.002	0.998	0.000
S81.9 Open wound of lower leg, part unspecified	0.002	0.998	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.998	0.002
O15.9 Eclampsia, unspecified as to time period	0.002	0.998	0.000
O15.2 Eclampsia in the puerperium	0.002	0.998	0.000
O15.1 Eclampsia in labour	0.002	0.998	0.000
O15.0 Eclampsia in pregnancy	0.002	0.998	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.002	0.998	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.002	0.998	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.002	0.998	0.000
O64.5 Obstructed labour due to compound presentation	0.002	0.998	0.000
O64.4 Obstructed labour due to shoulder presentation	0.002	0.998	0.000
O64.3 Obstructed labour due to brow presentation	0.002	0.998	0.000
O64.2 Obstructed labour due to face presentation	0.002	0.998	0.000
T90.4 Sequelae of injury of eye and orbit	0.002	0.998	0.000
O12.2 Gestational oedema with proteinuria	0.002	0.998	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.000	0.998	0.002
S69 Other and unspecified injuries of wrist and hand	0.002	0.998	0.000
S40-S49 Injuries to the shoulder and upper arm	0.002	0.998	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.002	0.998	0.000
O60.3 Preterm delivery without spontaneous labour	0.002	0.998	0.000
O60.2 Preterm spontaneous labour with term delivery	0.002	0.998	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.002	0.998	0.000
O60.0 Preterm labour without delivery	0.002	0.998	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.002	0.998	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.002	0.998	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.002	0.998	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.002	0.998	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.002	0.998	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.002	0.998	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.002	0.998	0.000
O65.0 Obstructed labour due to deformed pelvis	0.002	0.998	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.002	0.998	0.000
O67.8 Other intrapartum haemorrhage	0.002	0.998	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.002	0.998	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.002	0.998	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.002	0.998	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.002	0.998	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations