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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs185580150
log Bayes Factor = 0.118488
Chromosome 2   position 27,730,367  (GRCh37) Explore rs185580150 on Ensembl!
Variant rs185580150 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.237 0.763 0.000
Chapter XXI Factors influencing health status and contact with health services
0.235 0.765 0.000
Z85 Personal history of malignant neoplasm
0.230 0.770 0.000
# Top node
0.229 0.771 0.000
Chapter II Neoplasms
0.223 0.777 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.223 0.777 0.000
Chapter X Diseases of the respiratory system
0.217 0.783 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.212 0.788 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.209 0.791 0.000
Z80 Family history of malignant neoplasm
0.205 0.795 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.204 0.796 0.000
J30-J39 Other diseases of upper respiratory tract
0.196 0.804 0.000
J40-J47 Chronic lower respiratory diseases
0.194 0.806 0.000
C60-C63 Malignant neoplasms of male genital organs
0.193 0.807 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.193 0.807 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.193 0.807 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.190 0.810 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.189 0.811 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.187 0.813 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.183 0.817 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.181 0.818 0.000
C50-C50 Malignant neoplasm of breast
0.181 0.819 0.000
Z88.6 Personal history of allergy to analgesic agent
0.180 0.820 0.000
C15-C26 Malignant neoplasms of digestive organs
0.180 0.820 0.000
C64-C68 Malignant neoplasms of urinary tract
0.180 0.820 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.180 0.820 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.178 0.822 0.000
J45 Asthma
0.178 0.822 0.000
Chapter V Mental and behavioural disorders
0.176 0.824 0.000
Z90.7 Acquired absence of genital organ(s)
0.176 0.824 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.175 0.824 0.000
Chapter VII Diseases of the eye and adnexa
0.173 0.827 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.172 0.828 0.000
Z87 Personal history of other diseases and conditions
0.172 0.828 0.000
C61 Malignant neoplasm of prostate
0.172 0.828 0.000
Z80.3 Family history of malignant neoplasm of breast
0.171 0.829 0.000
Z92 Personal history of medical treatment
0.171 0.829 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.171 0.829 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.170 0.830 0.000
Z98 Other postsurgical states
0.170 0.830 0.000
Z97 Presence of other devices
0.170 0.830 0.000
Z94 Transplanted organ and tissue status
0.170 0.830 0.000
Z93 Artificial opening status
0.170 0.830 0.000
Z89 Acquired absence of limb
0.170 0.830 0.000
Z84 Family history of other conditions
0.170 0.830 0.000
Z83 Family history of other specific disorders
0.170 0.830 0.000
Z81 Family history of mental and behavioural disorders
0.170 0.830 0.000
D10-D36 Benign neoplasms
0.170 0.830 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.169 0.831 0.000
Chapter VI Diseases of the nervous system
0.169 0.831 0.000
Z13 Special screening examination for other diseases and disorders
0.169 0.831 0.000
Z88.5 Personal history of allergy to narcotic agent
0.167 0.833 0.000
C51-C58 Malignant neoplasms of female genital organs
0.167 0.833 0.000
J45.9 Asthma, unspecified
0.166 0.834 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.166 0.834 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.166 0.834 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.165 0.835 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.165 0.835 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.165 0.835 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.165 0.835 0.000
Z85.6 Personal history of leukaemia
0.165 0.835 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.165 0.835 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.165 0.835 0.000
Chapter XIV Diseases of the genitourinary system
0.165 0.835 0.000
Chapter XXII Codes for special purposes
0.164 0.836 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.164 0.836 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.164 0.836 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.164 0.836 0.000
Z86 Personal history of certain other diseases
0.163 0.837 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.163 0.837 0.000
J30 Vasomotor and allergic rhinitis
0.163 0.837 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.160 0.840 0.000
D00-D09 In situ neoplasms
0.160 0.840 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.160 0.840 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.160 0.840 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.160 0.840 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.160 0.840 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.160 0.840 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.160 0.840 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.160 0.840 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.160 0.840 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.160 0.840 0.000
Chapter XX External causes of morbidity and mortality
0.160 0.840 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.160 0.840 0.000
Z10 Routine general health check-up of defined subpopulation
0.160 0.840 0.000
Z04 Examination and observation for other reasons
0.160 0.840 0.000
Z02 Examination and encounter for administrative purposes
0.160 0.840 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.160 0.840 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.160 0.840 0.000
Chapter I Certain infectious and parasitic diseases
0.159 0.841 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.158 0.842 0.000
Z90.1 Acquired absence of breast(s)
0.158 0.842 0.000
Z03.4 Observation for suspected myocardial infarction
0.158 0.842 0.000
Z12 Special screening examination for neoplasms
0.158 0.842 0.000
J95-J99 Other diseases of the respiratory system
0.157 0.843 0.000
Chapter VIII Diseases of the ear and mastoid process
0.157 0.843 0.000
Z90.5 Acquired absence of kidney
0.157 0.843 0.000
J34 Other disorders of nose and nasal sinuses
0.157 0.843 0.000
J09-J18 Influenza and pneumonia
0.156 0.844 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.156 0.844 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.156 0.844 0.000
J90-J94 Other diseases of pleura
0.156 0.844 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.156 0.844 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.156 0.844 0.000
J60-J70 Lung diseases due to external agents
0.156 0.844 0.000
J00-J06 Acute upper respiratory infections
0.156 0.844 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.153 0.847 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.153 0.847 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.153 0.847 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.153 0.847 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.153 0.847 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.151 0.848 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.151 0.849 0.000
C50 Malignant neoplasm of breast
0.150 0.850 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.150 0.850 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.150 0.850 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.150 0.850 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.150 0.850 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.150 0.850 0.000
Z88.2 Personal history of allergy to sulphonamides
0.150 0.850 0.000
Z95.0 Presence of cardiac pacemaker
0.150 0.850 0.000
C18 Malignant neoplasm of colon
0.149 0.851 0.000
C67 Malignant neoplasm of bladder
0.149 0.851 0.000
J33 Nasal polyp
0.148 0.852 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.148 0.852 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.147 0.853 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.147 0.853 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.147 0.853 0.000
Z80.6 Family history of leukaemia
0.147 0.853 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.147 0.853 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.147 0.853 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.147 0.853 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.147 0.853 0.000
Z90.8 Acquired absence of other organs
0.146 0.854 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.146 0.854 0.000
Z90.3 Acquired absence of part of stomach
0.146 0.854 0.000
Z90.2 Acquired absence of lung [part of]
0.146 0.854 0.000
Z90.0 Acquired absence of part of head and neck
0.146 0.854 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.146 0.854 0.000
L60-L75 Disorders of skin appendages
0.146 0.854 0.000
J20-J22 Other acute lower respiratory infections
0.145 0.855 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.145 0.855 0.000
S00-S09 Injuries to the head
0.144 0.856 0.000
Z92.3 Personal history of irradiation
0.144 0.856 0.000
N30-N39 Other diseases of urinary system
0.144 0.856 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.143 0.857 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.142 0.858 0.000
J39 Other diseases of upper respiratory tract
0.140 0.860 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.140 0.860 0.000
J37 Chronic laryngitis and laryngotracheitis
0.140 0.860 0.000
J35 Chronic diseases of tonsils and adenoids
0.140 0.860 0.000
J32 Chronic sinusitis
0.140 0.860 0.000
J36 Peritonsillar abscess
0.140 0.860 0.000
J47 Bronchiectasis
0.139 0.860 0.000
J44 Other chronic obstructive pulmonary disease
0.139 0.861 0.000
J41 Simple and mucopurulent chronic bronchitis
0.139 0.861 0.000
J46 Status asthmaticus
0.139 0.861 0.000
J42 Unspecified chronic bronchitis
0.139 0.861 0.000
J40 Bronchitis, not specified as acute or chronic
0.139 0.861 0.000
J30.1 Allergic rhinitis due to pollen
0.139 0.861 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.139 0.861 0.000
C62 Malignant neoplasm of testis
0.139 0.861 0.000
C60 Malignant neoplasm of penis
0.139 0.861 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.139 0.861 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.139 0.861 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.139 0.861 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.139 0.861 0.000
C79 Secondary malignant neoplasm of other sites
0.139 0.861 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.139 0.861 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.138 0.862 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.137 0.862 0.000
J43 Emphysema
0.137 0.863 0.000
S60-S69 Injuries to the wrist and hand
0.137 0.863 0.000
S80-S89 Injuries to the knee and lower leg
0.137 0.863 0.000
Z03.8 Observation for other suspected diseases and conditions
0.137 0.863 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.136 0.863 0.000
T79-T79 Certain early complications of trauma
0.136 0.863 0.000
T66-T78 Other and unspecified effects of external causes
0.136 0.863 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.136 0.863 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.136 0.863 0.000
T33-T35 Frostbite
0.136 0.863 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.136 0.863 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.136 0.863 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.136 0.863 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.136 0.863 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.136 0.863 0.000
T00-T07 Injuries involving multiple body regions
0.136 0.863 0.000
S90-S99 Injuries to the ankle and foot
0.136 0.863 0.000
S70-S79 Injuries to the hip and thigh
0.136 0.863 0.000
S40-S49 Injuries to the shoulder and upper arm
0.136 0.863 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.136 0.863 0.000
S20-S29 Injuries to the thorax
0.136 0.863 0.000
S10-S19 Injuries to the neck
0.136 0.863 0.000
Z86.4 Personal history of psychoactive substance abuse
0.136 0.864 0.000
Z87.0 Personal history of diseases of the respiratory system
0.136 0.864 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.135 0.864 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.135 0.864 0.000
Z03.3 Observation for suspected nervous system disorder
0.135 0.864 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.135 0.864 0.000
Z03.1 Observation for suspected malignant neoplasm
0.135 0.864 0.000
Z03.0 Observation for suspected tuberculosis
0.135 0.864 0.000
O80-O84 Delivery
0.135 0.865 0.000
S50-S59 Injuries to the elbow and forearm
0.134 0.866 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.133 0.867 0.000
Z88.0 Personal history of allergy to penicillin
0.133 0.867 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.132 0.867 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.132 0.868 0.000
R07 Pain in throat and chest
0.132 0.868 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.131 0.868 0.000
H40-H42 Glaucoma
0.131 0.869 0.000
O85-O92 Complications predominantly related to the puerperium
0.131 0.869 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.131 0.869 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.131 0.869 0.000
O00-O08 Pregnancy with abortive outcome
0.131 0.869 0.000
H30-H36 Disorders of choroid and retina
0.131 0.869 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.131 0.869 0.000
C80 Malignant neoplasm without specification of site
0.130 0.870 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.130 0.870 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.130 0.870 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.129 0.871 0.000
C25 Malignant neoplasm of pancreas
0.129 0.871 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.129 0.871 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.129 0.871 0.000
C21 Malignant neoplasm of anus and anal canal
0.129 0.871 0.000
C17 Malignant neoplasm of small intestine
0.129 0.871 0.000
C16 Malignant neoplasm of stomach
0.129 0.871 0.000
C15 Malignant neoplasm of oesophagus
0.129 0.871 0.000
C23 Malignant neoplasm of gallbladder
0.129 0.871 0.000
C20 Malignant neoplasm of rectum
0.129 0.871 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.129 0.871 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.129 0.871 0.000
C66 Malignant neoplasm of ureter
0.129 0.871 0.000
C65 Malignant neoplasm of renal pelvis
0.129 0.871 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.129 0.871 0.000
G40-G47 Episodic and paroxysmal disorders
0.129 0.871 0.000
Z09.7 Follow-up examination after combined treatment for other conditions
0.129 0.871 0.000
Z09.4 Follow-up examination after treatment of fracture
0.129 0.871 0.000
Z09.3 Follow-up examination after psychotherapy
0.129 0.871 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.129 0.871 0.000
Z09.1 Follow-up examination after radiotherapy for other conditions
0.129 0.871 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.129 0.871 0.000
C50.9 Breast, unspecified
0.129 0.871 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.128 0.872 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.128 0.872 0.000
N10-N16 Renal tubulo-interstitial diseases
0.128 0.872 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.128 0.872 0.000
Z95.4 Presence of other heart-valve replacement
0.128 0.872 0.000
Z95.3 Presence of xenogenic heart valve
0.128 0.872 0.000
Z95.2 Presence of prosthetic heart valve
0.128 0.872 0.000
J45.8 Mixed asthma
0.127 0.872 0.000
J45.1 Nonallergic asthma
0.127 0.872 0.000
J45.0 Predominantly allergic asthma
0.127 0.872 0.000
D18 Haemangioma and lymphangioma, any site
0.127 0.872 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.127 0.873 0.000
Z47 Other orthopaedic follow-up care
0.127 0.873 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.127 0.873 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.127 0.873 0.000
F99-F99 Unspecified mental disorder
0.127 0.873 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.127 0.873 0.000
F80-F89 Disorders of psychological development
0.127 0.873 0.000
F70-F79 Mental retardation
0.127 0.873 0.000
F60-F69 Disorders of adult personality and behaviour
0.127 0.873 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.127 0.873 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.127 0.873 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.127 0.873 0.000
C54 Malignant neoplasm of corpus uteri
0.126 0.873 0.000
C67.9 Bladder, unspecified
0.126 0.874 0.000
T81 Complications of procedures, not elsewhere classified
0.126 0.874 0.000
O60-O75 Complications of labour and delivery
0.125 0.874 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.125 0.874 0.000
H55-H59 Other disorders of eye and adnexa
0.124 0.875 0.000
H53-H54 Visual disturbances and blindness
0.124 0.875 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.124 0.875 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.124 0.875 0.000
H43-H45 Disorders of vitreous body and globe
0.124 0.875 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.124 0.875 0.000
H10-H13 Disorders of conjunctiva
0.124 0.875 0.000
C77.2 Intra-abdominal lymph nodes
0.124 0.875 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.124 0.876 0.000
L40-L45 Papulosquamous disorders
0.124 0.876 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.124 0.876 0.000
L50-L54 Urticaria and erythema
0.124 0.876 0.000
L20-L30 Dermatitis and eczema
0.124 0.876 0.000
L10-L14 Bullous disorders
0.124 0.876 0.000
Z87.8 Personal history of other specified conditions
0.124 0.876 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.124 0.876 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.124 0.876 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.124 0.876 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.124 0.876 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.124 0.876 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.123 0.876 0.000
Z96 Presence of other functional implants
0.123 0.877 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.123 0.877 0.000
J31.0 Chronic rhinitis
0.123 0.877 0.000
R07.4 Chest pain, unspecified
0.123 0.877 0.000
Z92.9 Personal history of medical treatment, unspecified
0.123 0.877 0.000
Z92.8 Personal history of other medical treatment
0.123 0.877 0.000
Z92.5 Personal history of rehabilitation measures
0.123 0.877 0.000
Z92.0 Personal history of contraception
0.123 0.877 0.000
M20-M25 Other joint disorders
0.123 0.877 0.000
N39 Other disorders of urinary system
0.123 0.877 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.123 0.877 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.122 0.877 0.000
Z91.7 Personal history of female genital mutilation
0.122 0.877 0.000
Z91.6 Personal history of other physical trauma
0.122 0.877 0.000
Z91.5 Personal history of self-harm
0.122 0.877 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.122 0.877 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.122 0.877 0.000
Z91.2 Personal history of poor personal hygiene
0.122 0.877 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.122 0.877 0.000
Z81.8 Family history of other mental and behavioural disorders
0.122 0.878 0.000
Z81.4 Family history of other substance abuse
0.122 0.878 0.000
Z81.3 Family history of other psychoactive substance abuse
0.122 0.878 0.000
Z81.2 Family history of tobacco abuse
0.122 0.878 0.000
Z81.1 Family history of alcohol abuse
0.122 0.878 0.000
Z81.0 Family history of mental retardation
0.122 0.878 0.000
Z83.7 Family history of diseases of the digestive system
0.122 0.878 0.000
Z83.6 Family history of diseases of the respiratory system
0.122 0.878 0.000
Z83.5 Family history of eye and ear disorders
0.122 0.878 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.122 0.878 0.000
Z83.3 Family history of diabetes mellitus
0.122 0.878 0.000
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.122 0.878 0.000
Z83.1 Family history of other infectious and parasitic diseases
0.122 0.878 0.000
Z83.0 Family history of human immunodeficiency virus [HIV]
0.122 0.878 0.000
Z84.8 Family history of other specified conditions
0.122 0.878 0.000
Z84.3 Family history of consanguinity
0.122 0.878 0.000
Z84.2 Family history of other diseases of the genito-urinary system
0.122 0.878 0.000
Z84.1 Family history of disorders of the kidney and ureter
0.122 0.878 0.000
Z84.0 Family history of diseases of the skin and subcutaneous tissue
0.122 0.878 0.000
Z89.9 Acquired absence of limb, unspecified
0.122 0.878 0.000
Z89.8 Acquired absence of upper and lower limbs [any level]
0.122 0.878 0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]
0.122 0.878 0.000
Z89.6 Acquired absence of leg above knee
0.122 0.878 0.000
Z89.5 Acquired absence of leg at or below knee
0.122 0.878 0.000
Z89.4 Acquired absence of foot and ankle
0.122 0.878 0.000
Z89.3 Acquired absence of both upper limbs [any level]
0.122 0.878 0.000
Z89.2 Acquired absence of upper limb above wrist
0.122 0.878 0.000
Z89.1 Acquired absence of hand and wrist
0.122 0.878 0.000
Z89.0 Acquired absence of finger(s) [including thumb], unilateral
0.122 0.878 0.000
Z93.9 Artificial opening status, unspecified
0.122 0.878 0.000
Z93.8 Other artificial opening status
0.122 0.878 0.000
Z93.6 Other artificial openings of urinary tract status
0.122 0.878 0.000
Z93.5 Cystostomy status
0.122 0.878 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.122 0.878 0.000
Z93.3 Colostomy status
0.122 0.878 0.000
Z93.2 Ileostomy status
0.122 0.878 0.000
Z93.1 Gastrostomy status
0.122 0.878 0.000
Z93.0 Tracheostomy status
0.122 0.878 0.000
Z94.9 Transplanted organ and tissue status, unspecified
0.122 0.878 0.000
Z94.8 Other transplanted organ and tissue status
0.122 0.878 0.000
Z94.7 Corneal transplant status
0.122 0.878 0.000
Z94.6 Bone transplant status
0.122 0.878 0.000
Z94.5 Skin transplant status
0.122 0.878 0.000
Z94.4 Liver transplant status
0.122 0.878 0.000
Z94.3 Heart and lungs transplant status
0.122 0.878 0.000
Z94.2 Lung transplant status
0.122 0.878 0.000
Z94.1 Heart transplant status
0.122 0.878 0.000
Z94.0 Kidney transplant status
0.122 0.878 0.000
Z97.8 Presence of other specified devices
0.122 0.878 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.122 0.878 0.000
Z97.4 Presence of external hearing-aid
0.122 0.878 0.000
Z97.3 Presence of spectacles and contact lenses
0.122 0.878 0.000
Z97.2 Presence of dental prosthetic device (complete)(partial)
0.122 0.878 0.000
Z97.1 Presence of artificial limb (complete)(partial)
0.122 0.878 0.000
Z97.0 Presence of artificial eye
0.122 0.878 0.000
Z98.8 Other specified postsurgical states
0.122 0.878 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.122 0.878 0.000
Z98.1 Arthrodesis status
0.122 0.878 0.000
Z98.0 Intestinal bypass and anastomosis status
0.122 0.878 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.122 0.878 0.000
Z99.8 Dependence on other enabling machines and devices
0.122 0.878 0.000
Z99.4 Dependence on artificial heart
0.122 0.878 0.000
Z99.3 Dependence on wheelchair
0.122 0.878 0.000
Z99.2 Dependence on renal dialysis
0.122 0.878 0.000
Z99.1 Dependence on respirator
0.122 0.878 0.000
Z99.0 Dependence on aspirator
0.122 0.878 0.000
D36 Benign neoplasm of other and unspecified sites
0.122 0.878 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.122 0.878 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.122 0.878 0.000
D32 Benign neoplasm of meninges
0.122 0.878 0.000
D31 Benign neoplasm of eye and adnexa
0.122 0.878 0.000
D30 Benign neoplasm of urinary organs
0.122 0.878 0.000
D29 Benign neoplasm of male genital organs
0.122 0.878 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.122 0.878 0.000
D26 Other benign neoplasms of uterus
0.122 0.878 0.000
D23 Other benign neoplasms of skin
0.122 0.878 0.000
D22 Melanocytic naevi
0.122 0.878 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.122 0.878 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.122 0.878 0.000
D19 Benign neoplasm of mesothelial tissue
0.122 0.878 0.000
D16 Benign neoplasm of bone and articular cartilage
0.122 0.878 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.122 0.878 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.122 0.878 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.122 0.878 0.000
D11 Benign neoplasm of major salivary glands
0.122 0.878 0.000
D10 Benign neoplasm of mouth and pharynx
0.122 0.878 0.000
D34 Benign neoplasm of thyroid gland
0.122 0.878 0.000
D27 Benign neoplasm of ovary
0.122 0.878 0.000
D24 Benign neoplasm of breast
0.122 0.878 0.000
R00 Abnormalities of heart beat
0.122 0.878 0.000
C77.3 Axillary and upper limb lymph nodes
0.122 0.878 0.000
C18.0 Caecum
0.122 0.878 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.122 0.878 0.000
Z29 Need for other prophylactic measures
0.121 0.879 0.000
Z28 Immunisation not carried out
0.121 0.879 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.121 0.879 0.000
Z26 Need for immunisation against other single infectious diseases
0.121 0.879 0.000
Z25 Need for immunisation against other single viral diseases
0.121 0.879 0.000
Z24 Need for immunisation against certain single viral diseases
0.121 0.879 0.000
Z23 Need for immunisation against single bacterial diseases
0.121 0.879 0.000
Z22 Carrier of infectious disease
0.121 0.879 0.000
Z20 Contact with and exposure to communicable diseases
0.121 0.879 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.121 0.879 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.121 0.879 0.000
G90-G99 Other disorders of the nervous system
0.121 0.879 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.121 0.879 0.000
G70-G73 Diseases of myoneural junction and muscle
0.121 0.879 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.121 0.879 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.121 0.879 0.000
G30-G32 Other degenerative diseases of the nervous system
0.121 0.879 0.000
G20-G26 Extrapyramidal and movement disorders
0.121 0.879 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.121 0.879 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.121 0.879 0.000
Z45 Adjustment and management of implanted device
0.121 0.879 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.121 0.879 0.000
Z13.9 Special screening examination, unspecified
0.121 0.879 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.121 0.879 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.121 0.879 0.000
Z13.5 Special screening examination for eye and ear disorders
0.121 0.879 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.121 0.879 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.121 0.879 0.000
Z13.2 Special screening examination for nutritional disorders
0.121 0.879 0.000
Z13.1 Special screening examination for diabetes mellitus
0.121 0.879 0.000
F30-F39 Mood [affective] disorders
0.121 0.879 0.000
N40-N51 Diseases of male genital organs
0.120 0.879 0.000
J34.3 Hypertrophy of nasal turbinates
0.120 0.880 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.120 0.880 0.000
C53 Malignant neoplasm of cervix uteri
0.120 0.880 0.000
C51 Malignant neoplasm of vulva
0.120 0.880 0.000
C58 Malignant neoplasm of placenta
0.120 0.880 0.000
C56 Malignant neoplasm of ovary
0.120 0.880 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.120 0.880 0.000
C52 Malignant neoplasm of vagina
0.120 0.880 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.119 0.881 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.119 0.881 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.119 0.881 0.000
R47-R49 Symptoms and signs involving speech and voice
0.119 0.881 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.119 0.881 0.000
D17 Benign lipomatous neoplasm
0.119 0.881 0.000
H25-H28 Disorders of lens
0.119 0.881 0.000
B25-B34 Other viral diseases
0.119 0.881 0.000
Z85.02 Personal history of malignant neoplasm of stomach
0.118 0.881 0.000
N99-N99 Other disorders of the genitourinary system
0.118 0.881 0.000
N60-N64 Disorders of breast
0.118 0.881 0.000
N25-N29 Other disorders of kidney and ureter
0.118 0.881 0.000
N00-N08 Glomerular diseases
0.118 0.881 0.000
Z51 Other medical care
0.118 0.882 0.000
P90-P96 Other disorders originating in the perinatal period
0.118 0.882 0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.118 0.882 0.000
P75-P78 Digestive system disorders of fetus and newborn
0.118 0.882 0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.118 0.882 0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.118 0.882 0.000
P35-P39 Infections specific to the perinatal period
0.118 0.882 0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.118 0.882 0.000
P10-P15 Birth trauma
0.118 0.882 0.000
P05-P08 Disorders related to length of gestation and fetal growth
0.118 0.882 0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.118 0.882 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.118 0.882 0.000
Q80-Q89 Other congenital malformations
0.118 0.882 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.118 0.882 0.000
Q60-Q64 Congenital malformations of the urinary system
0.118 0.882 0.000
Q50-Q56 Congenital malformations of genital organs
0.118 0.882 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.118 0.882 0.000
Q35-Q37 Cleft lip and cleft palate
0.118 0.882 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.118 0.882 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.118 0.882 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.118 0.882 0.000
Q00-Q07 Congenital malformations of the nervous system
0.118 0.882 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.118 0.882 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.118 0.882 0.000
O48 Prolonged pregnancy
0.118 0.882 0.000
Z65 Problems related to other psychosocial circumstances
0.118 0.882 0.000
Z64 Problems related to certain psychosocial circumstances
0.118 0.882 0.000
Z63 Other problems related to primary support group, including family circumstances
0.118 0.882 0.000
Z62 Other problems related to upbringing
0.118 0.882 0.000
Z61 Problems related to negative life events in childhood
0.118 0.882 0.000
Z59 Problems related to housing and economic circumstances
0.118 0.882 0.000
Z58 Problems related to physical environment
0.118 0.882 0.000
Z57 Occupational exposure to risk-factors
0.118 0.882 0.000
Z56 Problems related to employment and unemployment
0.118 0.882 0.000
Z55 Problems related to education and literacy
0.118 0.882 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.117 0.883 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.117 0.883 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.117 0.883 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.117 0.883 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.117 0.883 0.000
J30.4 Allergic rhinitis, unspecified
0.117 0.883 0.000
J30.3 Other allergic rhinitis
0.117 0.883 0.000
J30.2 Other seasonal allergic rhinitis
0.117 0.883 0.000
J30.0 Vasomotor rhinitis
0.117 0.883 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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