TreeWAS – Variant ID: rs187650835

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter IX Diseases of the circulatory system	0.998	0.002
# Top node	0.997	0.003
I30-I52 Other forms of heart disease	0.995	0.005
Chapter II Neoplasms	0.995	0.005
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.986	0.014
Chapter XV Pregnancy, childbirth and the puerperium	0.977	0.023
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.966	0.034
I20-I25 Ischaemic heart diseases	0.948	0.052
D10-D36 Benign neoplasms	0.944	0.056
Chapter VI Diseases of the nervous system	0.943	0.057
I50 Heart failure	0.929	0.071
O60-O75 Complications of labour and delivery	0.929	0.071
S40-S49 Injuries to the shoulder and upper arm	0.924	0.076
G90-G99 Other disorders of the nervous system	0.907	0.093
I24 Other acute ischaemic heart diseases	0.904	0.096
I35 Nonrheumatic aortic valve disorders	0.900	0.100
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.898	0.102
D37-D48 Neoplasms of uncertain or unknown behaviour	0.894	0.106
D00-D09 In situ neoplasms	0.883	0.117
S42 Fracture of shoulder and upper arm	0.880	0.120
D24 Benign neoplasm of breast	0.874	0.126
I60-I69 Cerebrovascular diseases	0.874	0.126
D22 Melanocytic naevi	0.873	0.127
I31 Other diseases of pericardium	0.870	0.130
S00-S09 Injuries to the head	0.861	0.139
O68 Labour and delivery complicated by foetal stress [distress]	0.857	0.143
I05-I09 Chronic rheumatic heart diseases	0.857	0.143
C78.0 Secondary malignant neoplasm of lung	0.855	0.145
G93 Other disorders of brain	0.850	0.150
I20 Angina pectoris	0.850	0.150
O00-O08 Pregnancy with abortive outcome	0.846	0.154
Chapter XXI Factors influencing health status and contact with health services	0.842	0.158
I47 Paroxysmal tachycardia	0.839	0.161
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.838	0.162
I50.0 Congestive heart failure	0.837	0.163
S20-S29 Injuries to the thorax	0.836	0.164
S42.2 Fracture of upper end of humerus	0.824	0.176
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.818	0.182
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.808	0.192
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.808	0.192
I24.9 Acute ischaemic heart disease, unspecified	0.807	0.193
C79 Secondary malignant neoplasm of other sites	0.806	0.194
I51 Complications and ill-defined descriptions of heart disease	0.804	0.196
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.802	0.198
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.801	0.199
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.795	0.205
G80-G83 Cerebral palsy and other paralytic syndromes	0.792	0.208
C78.7 Secondary malignant neoplasm of liver	0.789	0.211
S01 Open wound of head	0.787	0.213
I24.8 Other forms of acute ischaemic heart disease	0.786	0.214
I31.3 Pericardial effusion (noninflammatory)	0.784	0.216
S42.20 Fracture of upper end of humerus (closed)	0.784	0.216
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.783	0.217
D06 Carcinoma in situ of cervix uteri	0.783	0.217
I33 Acute and subacute endocarditis	0.780	0.220
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.780	0.220
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.779	0.221
I35.0 Aortic (valve) stenosis	0.775	0.225
D22.5 Melanocytic naevi of trunk	0.775	0.225
I42 Cardiomyopathy	0.774	0.226
C80 Malignant neoplasm without specification of site	0.769	0.231
D45 Polycythaemia vera	0.768	0.232
Chapter XX External causes of morbidity and mortality	0.766	0.234
I67 Other cerebrovascular diseases	0.765	0.235
S10-S19 Injuries to the neck	0.762	0.238
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.762	0.238
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.761	0.239
D29 Benign neoplasm of male genital organs	0.761	0.239
Chapter XXII Codes for special purposes	0.759	0.240
O72 Postpartum haemorrhage	0.759	0.241
G20-G26 Extrapyramidal and movement disorders	0.756	0.244
D22.7 Melanocytic naevi of lower limb, including hip	0.756	0.244
G93.4 Encephalopathy, unspecified	0.753	0.247
S60-S69 Injuries to the wrist and hand	0.752	0.248
D33 Benign neoplasm of brain and other parts of central nervous system	0.752	0.248
O94-O99 Other obstetric conditions, not elsewhere classified	0.750	0.250
I47.2 Ventricular tachycardia	0.748	0.252
I10-I15 Hypertensive diseases	0.746	0.254
C51-C58 Malignant neoplasms of female genital organs	0.745	0.255
Chapter VIII Diseases of the ear and mastoid process	0.745	0.255
I50.9 Heart failure, unspecified	0.742	0.258
I46 Cardiac arrest	0.741	0.259
S42.0 Fracture of clavicle	0.741	0.259
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.740	0.260
I35.1 Aortic (valve) insufficiency	0.739	0.261
I34 Nonrheumatic mitral valve disorders	0.737	0.263
I50.1 Left ventricular failure	0.737	0.263
I44 Atrioventricular and left bundle-branch block	0.734	0.266
D23 Other benign neoplasms of skin	0.732	0.268
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.731	0.268
O64 Obstructed labour due to malposition and malpresentation of foetus	0.731	0.269
O03 Spontaneous abortion	0.730	0.270
D17 Benign lipomatous neoplasm	0.729	0.271
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.728	0.272
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.725	0.275
I95-I99 Other and unspecified disorders of the circulatory system	0.724	0.276
I80 Phlebitis and thrombophlebitis	0.722	0.278
T15-T19 Effects of foreign body entering through natural orifice	0.722	0.278
I08 Multiple valve diseases	0.721	0.279
I20.0 Unstable angina	0.721	0.279
I61 Intracerebral haemorrhage	0.719	0.281
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.716	0.284
I00-I02 Acute rheumatic fever	0.716	0.284
Chapter XVI Certain conditions originating in the perinatal period	0.715	0.285
I38 Endocarditis, valve unspecified	0.715	0.285
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.715	0.285
I52 Other heart disorders in diseases classified elsewhere	0.713	0.287
I48 Atrial fibrillation and flutter	0.713	0.287
I43 Cardiomyopathy in diseases classified elsewhere	0.713	0.287
I41 Myocarditis in diseases classified elsewhere	0.713	0.287
I40 Acute myocarditis	0.713	0.287
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.713	0.287
I37 Pulmonary valve disorders	0.713	0.287
I36 Nonrheumatic tricuspid valve disorders	0.713	0.287
I32 Pericarditis in diseases classified elsewhere	0.713	0.287
I30 Acute pericarditis	0.713	0.287
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.713	0.287
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.713	0.287
C40-C41 Malignant neoplasms of bone and articular cartilage	0.713	0.287
G30-G32 Other degenerative diseases of the nervous system	0.713	0.287
O66 Other obstructed labour	0.713	0.287
I26 Pulmonary embolism	0.712	0.288
D35 Benign neoplasm of other and unspecified endocrine glands	0.712	0.288
I25 Chronic ischaemic heart disease	0.711	0.289
D06.9 Cervix, unspecified	0.711	0.289
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.711	0.289
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.710	0.290
O62 Abnormalities of forces of labour	0.708	0.292
O20-O29 Other maternal disorders predominantly related to pregnancy	0.707	0.293
T79-T79 Certain early complications of trauma	0.707	0.293
T33-T35 Frostbite	0.707	0.293
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.707	0.293
T26-T28 Burns and corrosions confined to eye and internal organs	0.707	0.293
T20-T25 Burns and corrosions of external body surface, specified by site	0.707	0.293
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.707	0.293
T00-T07 Injuries involving multiple body regions	0.707	0.293
S90-S99 Injuries to the ankle and foot	0.707	0.293
S70-S79 Injuries to the hip and thigh	0.705	0.295
O63 Long labour	0.705	0.295
T66-T78 Other and unspecified effects of external causes	0.702	0.298
G99 Other disorders of nervous system in diseases classified elsewhere	0.701	0.299
O85-O92 Complications predominantly related to the puerperium	0.701	0.299
T93 Sequelae of injuries of lower limb	0.698	0.302
S01.8 Open wound of other parts of head	0.698	0.302
G93.2 Benign intracranial hypertension	0.698	0.302
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.697	0.303
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.696	0.304
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.695	0.305
G93.6 Cerebral oedema	0.694	0.305
I22 Subsequent myocardial infarction	0.693	0.307
I12 Hypertensive renal disease	0.693	0.307
C76 Malignant neoplasm of other and ill-defined sites	0.692	0.308
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.691	0.309
T85 Complications of other internal prosthetic devices, implants and grafts	0.689	0.311
I49 Other cardiac arrhythmias	0.687	0.313
D46 Myelodysplastic syndromes	0.687	0.313
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.686	0.314
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.682	0.318
O36 Maternal care for other known or suspected foetal problems	0.681	0.319
I35.2 Aortic (valve) stenosis with insufficiency	0.681	0.319
G95 Other diseases of spinal cord	0.680	0.320
Z95 Presence of cardiac and vascular implants and grafts	0.680	0.320
I23 Certain current complications following acute myocardial infarction	0.679	0.320
S62 Fracture at wrist and hand level	0.677	0.323
D32 Benign neoplasm of meninges	0.677	0.323
D31 Benign neoplasm of eye and adnexa	0.677	0.323
D30 Benign neoplasm of urinary organs	0.677	0.323
D28 Benign neoplasm of other and unspecified female genital organs	0.677	0.323
D26 Other benign neoplasms of uterus	0.677	0.323
D21 Other benign neoplasms of connective and other soft tissue	0.677	0.323
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.677	0.323
D19 Benign neoplasm of mesothelial tissue	0.677	0.323
D16 Benign neoplasm of bone and articular cartilage	0.677	0.323
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.677	0.323
D14 Benign neoplasm of middle ear and respiratory system	0.677	0.323
D10 Benign neoplasm of mouth and pharynx	0.677	0.323
D34 Benign neoplasm of thyroid gland	0.677	0.323
I07 Rheumatic tricuspid valve diseases	0.677	0.323
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.677	0.323
C60-C63 Malignant neoplasms of male genital organs	0.676	0.324
G70-G73 Diseases of myoneural junction and muscle	0.676	0.324
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.676	0.324
G00-G09 Inflammatory diseases of the central nervous system	0.676	0.324
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.675	0.324
G35-G37 Demyelinating diseases of the central nervous system	0.674	0.325
Z34 Supervision of normal pregnancy	0.673	0.327
I20.9 Angina pectoris, unspecified	0.672	0.328
S29 Other and unspecified injuries of thorax	0.672	0.328
I51.9 Heart disease, unspecified	0.671	0.329
C64-C68 Malignant neoplasms of urinary tract	0.670	0.330
Z35 Supervision of high-risk pregnancy	0.668	0.332
I67.8 Other specified cerebrovascular diseases	0.666	0.334
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.666	0.334
O75 Other complications of labour and delivery, not elsewhere classified	0.666	0.334
O74 Complications of anaesthesia during labour and delivery	0.666	0.334
O73 Retained placenta and membranes, without haemorrhage	0.666	0.334
O71 Other obstetric trauma	0.666	0.334
O69 Labour and delivery complicated by umbilical cord complications	0.666	0.334
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.666	0.334
O65 Obstructed labour due to maternal pelvic abnormality	0.666	0.334
O61 Failed induction of labour	0.666	0.334
O60 Preterm delivery	0.666	0.334
G83 Other paralytic syndromes	0.663	0.337
S49 Other and unspecified injuries of shoulder and upper arm	0.662	0.337
S48 Traumatic amputation of shoulder and upper arm	0.662	0.337
S46 Injury of muscle and tendon at shoulder and upper arm level	0.662	0.337
S45 Injury of blood vessels at shoulder and upper arm level	0.662	0.337
S44 Injury of nerves at shoulder and upper arm level	0.662	0.337
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.662	0.337
S41 Open wound of shoulder and upper arm	0.662	0.337
S40 Superficial injury of shoulder and upper arm	0.662	0.337
S47 Crushing injury of shoulder and upper arm	0.662	0.337
D05 Carcinoma in situ of breast	0.662	0.338
S02 Fracture of skull and facial bones	0.661	0.339
D18 Haemangioma and lymphangioma, any site	0.660	0.340
D07 Carcinoma in situ of other and unspecified genital organs	0.659	0.340
Z40-Z54 Persons encountering health services for specific procedures and health care	0.660	0.340
I20.1 Angina pectoris with documented spasm	0.659	0.341
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.657	0.343
C92 Myeloid leukaemia	0.657	0.343
O02 Other abnormal products of conception	0.656	0.344
D11 Benign neoplasm of major salivary glands	0.655	0.344
I45 Other conduction disorders	0.655	0.344
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.652	0.348
G96 Other disorders of central nervous system	0.650	0.350
G94 Other disorders of brain in diseases classified elsewhere	0.650	0.350
G91 Hydrocephalus	0.650	0.350
G90 Disorders of autonomic nervous system	0.650	0.350
G98 Other disorders of nervous system, not elsewhere classified	0.650	0.350
G92 Toxic encephalopathy	0.650	0.350
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.649	0.351
I24.1 Dressler's syndrome	0.648	0.352
Chapter X Diseases of the respiratory system	0.646	0.354
I35.9 Aortic valve disorder, unspecified	0.645	0.355
I35.8 Other aortic valve disorders	0.645	0.355
S27 Injury of other and unspecified intrathoracic organs	0.645	0.355
S22 Fracture of rib(s), sternum and thoracic spine	0.645	0.355
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.644	0.356
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.644	0.356
C78.4 Secondary malignant neoplasm of small intestine	0.644	0.356
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.644	0.356
C78.1 Secondary malignant neoplasm of mediastinum	0.644	0.356
I12.0 Hypertensive renal disease with renal failure	0.643	0.357
S42.00 Fracture of clavicle (closed)	0.641	0.358
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.641	0.359
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.641	0.359
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.641	0.359
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.641	0.359
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.641	0.359
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.641	0.359
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.641	0.359
S50-S59 Injuries to the elbow and forearm	0.641	0.359
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.641	0.359
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.641	0.359
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.637	0.363
C79.9 Secondary malignant neoplasm, unspecified site	0.634	0.366
D09 Carcinoma in situ of other and unspecified sites	0.633	0.366
D04 Carcinoma in situ of skin	0.633	0.366
D03 Melanoma in situ	0.633	0.366
D02 Carcinoma in situ of middle ear and respiratory system	0.633	0.366
D01 Carcinoma in situ of other and unspecified digestive organs	0.633	0.366
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.633	0.366
S80-S89 Injuries to the knee and lower leg	0.633	0.367
S42.9 Fracture of shoulder girdle, part unspecified	0.631	0.369
S42.8 Fracture of other parts of shoulder and upper arm	0.631	0.369
S42.7 Multiple fractures of clavicle, scapula and humerus	0.631	0.369
S42.4 Fracture of lower end of humerus	0.631	0.369
S42.1 Fracture of scapula	0.631	0.369
Q20-Q28 Congenital malformations of the circulatory system	0.630	0.370
D29.1 Prostate	0.629	0.371
D22.3 Melanocytic naevi of other and unspecified parts of face	0.629	0.371
I08.1 Disorders of both mitral and tricuspid valves	0.629	0.371
I20.8 Other forms of angina pectoris	0.628	0.372
Z95.0 Presence of cardiac pacemaker	0.628	0.372
C80.9 Malignant neoplasm, unspecified	0.628	0.372
S42.3 Fracture of shaft of humerus	0.627	0.372
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.627	0.373
I68 Cerebrovascular disorders in diseases classified elsewhere	0.627	0.373
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.627	0.373
O03.9 Complete or unspecified, without complication	0.626	0.373
I33.0 Acute and subacute infective endocarditis	0.626	0.374
I62 Other nontraumatic intracranial haemorrhage	0.626	0.374
D22.9 Melanocytic naevi, unspecified	0.626	0.374
D22.4 Melanocytic naevi of scalp and neck	0.626	0.374
D22.2 Melanocytic naevi of ear and external auricular canal	0.626	0.374
D22.1 Melanocytic naevi of eyelid, including canthus	0.626	0.374
D22.0 Melanocytic naevi of lip	0.626	0.374
C34 Malignant neoplasm of bronchus and lung	0.625	0.375
I31.8 Other specified diseases of pericardium	0.623	0.376
I31.2 Haemopericardium, not elsewhere classified	0.623	0.376
I31.1 Chronic constrictive pericarditis	0.623	0.376
I31.0 Chronic adhesive pericarditis	0.623	0.376
O00 Ectopic pregnancy	0.623	0.377
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.622	0.378
C77.8 Lymph nodes of multiple regions	0.622	0.378
I27 Other pulmonary heart diseases	0.620	0.380
G97.1 Other reaction to spinal and lumbar puncture	0.620	0.380
S08 Traumatic amputation of part of head	0.617	0.382
S07 Crushing injury of head	0.617	0.382
S05 Injury of eye and orbit	0.617	0.382
S04 Injury of cranial nerves	0.617	0.382
S03 Dislocation, sprain and strain of joints and ligaments of head	0.617	0.382
D27 Benign neoplasm of ovary	0.617	0.383
Z95.5 Presence of coronary angioplasty implant and graft	0.617	0.383
D36 Benign neoplasm of other and unspecified sites	0.616	0.384
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.615	0.385
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.615	0.385
I09 Other rheumatic heart diseases	0.615	0.385
I06 Rheumatic aortic valve diseases	0.615	0.385
I05 Rheumatic mitral valve diseases	0.615	0.385
D33.3 Cranial nerves	0.614	0.386
I25.9 Chronic ischaemic heart disease, unspecified	0.614	0.386
I69 Sequelae of cerebrovascular disease	0.612	0.388
S06 Intracranial injury	0.612	0.388
I31.9 Disease of pericardium, unspecified	0.611	0.389
S00 Superficial injury of head	0.610	0.390
D17.9 Benign lipomatous neoplasm, unspecified	0.610	0.390
G93.9 Disorder of brain, unspecified	0.610	0.390
G93.8 Other specified disorders of brain	0.610	0.390
G93.7 Reye's syndrome	0.610	0.390
G93.5 Compression of brain	0.610	0.390
G93.3 Postviral fatigue syndrome	0.610	0.390
G93.1 Anoxic brain damage, not elsewhere classified	0.610	0.390
G93.0 Cerebral cysts	0.610	0.390
Chapter VII Diseases of the eye and adnexa	0.609	0.391
O72.1 Other immediate postpartum haemorrhage	0.609	0.391
C79.7 Secondary malignant neoplasm of adrenal gland	0.608	0.392
S01.0 Open wound of scalp	0.608	0.392
I64 Stroke, not specified as haemorrhage or infarction	0.607	0.393
C83 Diffuse non-Hodgkin's lymphoma	0.607	0.393
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.607	0.393
O08 Complications following abortion and ectopic and molar pregnancy	0.607	0.393
O07 Failed attempted abortion	0.607	0.393
O06 Unspecified abortion	0.607	0.393
O05 Other abortion	0.607	0.393
O01 Hydatidiform mole	0.607	0.393
I60 Subarachnoid haemorrhage	0.605	0.395
G81 Hemiplegia	0.605	0.395
S01.3 Open wound of ear	0.604	0.396
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.604	0.396
S19 Other and unspecified injuries of neck	0.602	0.398
G20 Parkinson's disease	0.602	0.398
I47.9 Paroxysmal tachycardia, unspecified	0.602	0.398
I47.0 Reentry ventricular arrhythmia	0.602	0.398
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.601	0.399
I28 Other diseases of pulmonary vessels	0.601	0.399
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.600	0.400
I42.9 Cardiomyopathy, unspecified	0.600	0.400
O80-O84 Delivery	0.600	0.400
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.599	0.400
S26 Injury of heart	0.599	0.400
S25 Injury of blood vessels of thorax	0.599	0.400
S24 Injury of nerves and spinal cord at thorax level	0.599	0.400
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.599	0.400
S21 Open wound of thorax	0.599	0.400
S20 Superficial injury of thorax	0.599	0.400
C77.5 Intrapelvic lymph nodes	0.599	0.401
O46 Antepartum haemorrhage, not elsewhere classified	0.597	0.403
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.597	0.403
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.596	0.403
D22.6 Melanocytic naevi of upper limb, including shoulder	0.596	0.404
O48 Prolonged pregnancy	0.596	0.404
S62.6 Fracture of other finger	0.595	0.405
D23.7 Skin of lower limb, including hip	0.595	0.405
Z86 Personal history of certain other diseases	0.593	0.407
C90 Multiple myeloma and malignant plasma cell neoplasms	0.593	0.407
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.592	0.408
Z33 Pregnant state, incidental	0.592	0.408
Z36 Antenatal screening	0.592	0.408
I51.7 Cardiomegaly	0.592	0.408
Z48 Other surgical follow-up care	0.591	0.408
S42.21 Fracture of upper end of humerus (open)	0.591	0.409
X60-X84 Intentional self-harm	0.591	0.409
Z30 Contraceptive management	0.591	0.409
S01.9 Open wound of head, part unspecified	0.590	0.409
J30-J39 Other diseases of upper respiratory tract	0.589	0.411
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.589	0.411
O42 Premature rupture of membranes	0.589	0.411
C77.1 Intrathoracic lymph nodes	0.589	0.411
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.588	0.412
O04 Medical abortion	0.587	0.413
T98 Sequelae of other and unspecified effects of external causes	0.587	0.413
T95 Sequelae of burns, corrosions and frostbite	0.587	0.413
T94 Sequelae of injuries involving multiple and unspecified body regions	0.587	0.413
T92 Sequelae of injuries of upper limb	0.587	0.413
T91 Sequelae of injuries of neck and trunk	0.587	0.413
T90 Sequelae of injuries of head	0.587	0.413
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.587	0.413
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.587	0.413
I44.0 Atrioventricular block, first degree	0.586	0.414
O72.2 Delayed and secondary postpartum haemorrhage	0.585	0.415
S30 Superficial injury of abdomen, lower back and pelvis	0.584	0.416
H60-H62 Diseases of external ear	0.584	0.416
S32 Fracture of lumbar spine and pelvis	0.583	0.417
C54 Malignant neoplasm of corpus uteri	0.581	0.418
C91 Lymphoid leukaemia	0.581	0.418
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.581	0.419
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.581	0.419
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.580	0.420
I63 Cerebral infarction	0.580	0.420
T81 Complications of procedures, not elsewhere classified	0.580	0.420
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.579	0.421
C95 Leukaemia of unspecified cell type	0.579	0.421
C94 Other leukaemias of specified cell type	0.579	0.421
C93 Monocytic leukaemia	0.579	0.421
C88 Malignant immunoproliferative diseases	0.579	0.421
C86 Other specified types of T/NK-cell lymphoma	0.579	0.421
C84 Peripheral and cutaneous T-cell lymphomas	0.579	0.421
C81 Hodgkin's disease	0.579	0.421
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.579	0.421
S37 Injury of urinary and pelvic organs	0.579	0.421
S36 Injury of intra-abdominal organs	0.579	0.421
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.579	0.421
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.579	0.421
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.579	0.421
S31 Open wound of abdomen, lower back and pelvis	0.579	0.421
C79.6 Secondary malignant neoplasm of ovary	0.578	0.422
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.578	0.422
C79.2 Secondary malignant neoplasm of skin	0.578	0.422
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.578	0.422
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.578	0.422
W20-W49 Exposure to inanimate mechanical forces	0.578	0.422
I85 Oesophageal varices	0.577	0.423
C50-C50 Malignant neoplasm of breast	0.577	0.423
I51.6 Cardiovascular disease, unspecified	0.577	0.423
I51.5 Myocardial degeneration	0.577	0.423
I51.4 Myocarditis, unspecified	0.577	0.423
I51.3 Intracardiac thrombosis, not elsewhere classified	0.577	0.423
I51.2 Rupture of papillary muscle, not elsewhere classified	0.577	0.423
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.577	0.423
I51.0 Cardiac septal defect, acquired	0.577	0.423
H80-H83 Diseases of inner ear	0.576	0.423
O16 Unspecified maternal hypertension	0.576	0.424
I67.1 Cerebral aneurysm, nonruptured	0.575	0.425
I88 Nonspecific lymphadenitis	0.575	0.425
I87 Other disorders of veins	0.575	0.425
I86 Varicose veins of other sites	0.575	0.425
I82 Other venous embolism and thrombosis	0.575	0.425
I81 Portal vein thrombosis	0.575	0.425
I42.0 Dilated cardiomyopathy	0.575	0.425
O45 Premature separation of placenta [abruptio placentae]	0.574	0.426
O44 Placenta praevia	0.574	0.426
O43 Placental disorders	0.574	0.426
O41 Other disorders of amniotic fluid and membranes	0.574	0.426
O35 Maternal care for known or suspected foetal abnormality and damage	0.574	0.426
O33 Maternal care for known or suspected disproportion	0.574	0.426
O31 Complications specific to multiple gestation	0.574	0.426
O30 Multiple gestation	0.574	0.426
O40 Polyhydramnios	0.574	0.426
C77.3 Axillary and upper limb lymph nodes	0.573	0.427
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.572	0.428
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.572	0.428
Z94 Transplanted organ and tissue status	0.572	0.428
O47 False labour	0.571	0.429
G25 Other extrapyramidal and movement disorders	0.571	0.429
G83.4 Cauda equina syndrome	0.571	0.429
C78.2 Secondary malignant neoplasm of pleura	0.570	0.430
T88 Other complications of surgical and medical care, not elsewhere classified	0.570	0.430
T87 Complications peculiar to reattachment and amputation	0.570	0.430
T86 Failure and rejection of transplanted organs and tissues	0.570	0.430
T80 Complications following infusion, transfusion and therapeutic injection	0.570	0.430
I67.9 Cerebrovascular disease, unspecified	0.570	0.430
Z22 Carrier of infectious disease	0.569	0.431
G82 Paraplegia and tetraplegia	0.568	0.432
G80 Infantile cerebral palsy	0.568	0.432
I70-I79 Diseases of arteries, arterioles and capillaries	0.567	0.432
Z95.4 Presence of other heart-valve replacement	0.567	0.433
D17.7 Benign lipomatous neoplasm of other sites	0.567	0.433
S01.5 Open wound of lip and oral cavity	0.567	0.433
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.566	0.434
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.565	0.435
S01.7 Multiple open wounds of head	0.564	0.435
S01.4 Open wound of cheek and temporomandibular area	0.564	0.435
S01.2 Open wound of nose	0.564	0.435
T93.2 Sequelae of other fractures of lower limb	0.564	0.435
I49.9 Cardiac arrhythmia, unspecified	0.564	0.436
O03.4 Incomplete, without complication	0.563	0.437
D23.5 Skin of trunk	0.563	0.437
V20-V29 Motorcycle rider injured in transport accident	0.562	0.438
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.562	0.438
Q80-Q89 Other congenital malformations	0.562	0.438
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.562	0.438
Q60-Q64 Congenital malformations of the urinary system	0.562	0.438
Q50-Q56 Congenital malformations of genital organs	0.562	0.438
Q38-Q45 Other congenital malformations of the digestive system	0.562	0.438
Q35-Q37 Cleft lip and cleft palate	0.562	0.438
Q30-Q34 Congenital malformations of the respiratory system	0.562	0.438
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.562	0.438
Q00-Q07 Congenital malformations of the nervous system	0.562	0.438
D06.7 Other parts of cervix	0.561	0.439
D06.1 Exocervix	0.561	0.439
D06.0 Endocervix	0.561	0.439
O36.9 Maternal care for foetal problem, unspecified	0.560	0.440
Z34.8 Supervision of other normal pregnancy	0.560	0.440
I33.9 Acute endocarditis, unspecified	0.559	0.441
I46.0 Cardiac arrest with successful resuscitation	0.559	0.441
Z39 Postpartum care and examination	0.559	0.441
Z38 Liveborn infants according to place of birth	0.559	0.441
Z32 Pregnancy examination and test	0.559	0.441
Z31 Procreative management	0.559	0.441

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations